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Basic medical science insights from a final year medical student
Apple podcast: https://itunes.apple.com/gb/podcast/basic-medical-science-insights/id1439016520
DISCLAIMER:
I am a UK medical student and am neither a qualified doctor nor a professional scientist (yet).
The content in this channel may contain factual errors.
I do not intend to profess myself as an expert on any of the topics discussed and further information should be sought on accredited platforms, such as BMJ Best Practice and PubMed/COCHRANE. Medical advice should be sought from your physician.
Apple podcast: https://itunes.apple.com/gb/podcast/basic-medical-science-insights/id1439016520
DISCLAIMER:
I am a UK medical student and am neither a qualified doctor nor a professional scientist (yet).
The content in this channel may contain factual errors.
I do not intend to profess myself as an expert on any of the topics discussed and further information should be sought on accredited platforms, such as BMJ Best Practice and PubMed/COCHRANE. Medical advice should be sought from your physician.
فرکانس به روز رسانی:
every 11 hours
میانگین طول صدا:
9 minutes
انگلیسی
ایالات متحده آمریکا
52 قسمت
از سال 20 سپتامبر 2018
episodic
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Insights:
Sepsis 6
Encapsulated bacteria (ANTIBIOTICS)
Hemodynamic problem (increased vasc permeability by loosening tight junctions between ECs) (FLUIDS, MEASURE URINE OUTPUT)
Metabolic disturbances (hyperglycaemia, insulin resistance, high cortisol, lactic acidosis (OXYGEN, VBG)
Acute kidney in…
Insights:
Concept of sepsis as an overwhelming infection where our body CANNOT mount a sufficient antibody response against it (usually in SPLEEN if bacteraemia). The course of damage occurs due to release of overwhelming amount of pro-inflammatory cytokines.
First it’s TNFalpha and IL-1b that ki…
Insights:
Cranial has its own origin, migration pattern and differentiation.
Circumpharyngeal has a special distribution around pharyngeal arches, has two key branches (cardiac and vagal) and runs anteriorly to supply hypoglossal nerve (video says vagus by mistake)
Trunk has unique directions o…
Insights:
Increased susceptibility to encapsulated bacterial sepsis (side note, in Bruton agam, also increased risk of this)
Child greater than adults (fewer memory B cells)
Immune reasons: fewer antibody responses to blood bourne pathogens, fewer phagocytes (side note, in Bruton agam, also incr…
Insights:
The skull is a unique structure, organised by pharyngeal arches and reinforced with neural crest cells.
The skull is divided into neurocranium and viscerocranium. They are further subdivided into a membranous cranium (where bones form via intramembranous ossification) and cartilaginous …
Insights:
Neural crest cells have a variety of fates, including teeth, skull bones, melanocytes, sympathetic ganglia, Schwaan cells and adrenal medulla.
Neural cells undergo induction, migration and differentiation to form the full variety of tissue they form. Induction depends on exposure to in…
Insights:
The placenta needs to make oestrogens and progesterone to maintain pregnancy and prepare mother for postpartum period. The fetus needs to make cortisol for organ maturation.
Fetus cannot make oestrogens and progesterons, but placenta can. Placenta has 3betaHSD that can make progesterone…
Insights:
Vasculitides can be characterised by hypersensitivity reactions: type 1 (Churg-Strauss), type 2 (Kawasaki), type 3 (polyarteritis nodosa) and type 4 (granulomatosis with polyangiitis).
Endothelial dysfunction can lead to a hypercoagulable state, endothelial hyperplasia narrows the lume…
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