Under Pressure

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What happens to the human body in the most extreme environments? In this episode, we’re joined by Dr. Scott Parazynski – physician, innovator and former NASA astronaut – for a conversation that goes far beyond the operating room. Dr. Parazynski shares insight from his time at NASA, his medical trai…

Dr. Samir Mehta joins Under Pressure for a conversation on orthopaedic trauma, surgical judgment, innovation, and the evolving role of data in medicine. From teaching residents and building expertise in high-pressure environments to advancing personalized approaches for predicting fracture healing,…

In this episode, Dr. William Obremskey joins us for a discussion on how compartment syndrome actually presents in practice, the realities of surgical decompression, and the difficult scenarios surgeons rarely talk about, including what happens when a compartment is no longer viable. We also explore…

Acute compartment syndrome is one of the most feared diagnoses in orthopaedic trauma, yet despite decades of teaching, controversy and uncertainty remain. In this episode, Dr. Andrew Schmidt joins us for a thoughtful and refreshingly candid discussion on why compartment syndrome continues to genera…

When surgeons talk about compartment syndrome, the focus is often on diagnosis and surgical urgency. Far less attention is given to what happens next for the patient. In this episode, Dr. Christopher Doro joins us for a conversation on the downstream realities of acute compartment syndrome, recover…

Trauma care doesn’t happen in a vacuum, and neither does innovation. In this episode, Dr. Jonathan Sackier sits down with Dr. Sandip Tarpada, orthopaedic trauma surgeon at Harlem Hospital Center, to explore how cutting-edge science meets real-world constraints. From his work on DNA methylation as a…

Pediatric trauma brings a unique set of challenges, from subtle clinical signs to children who can’t always articulate what hurts, and injury patterns that behave differently than those of adults. In this episode, Dr. Jonathan Sackier sits down with Dr. Kristin Livingston, pediatric orthopaedic sur…

In this episode of Under Pressure, Dr. O’Toole takes us inside landmark studies like VANCO and PREVENT CLOT, explaining what they mean for infection prevention, VTE prophylaxis, and real-world surgical protocols. He also shares why research consortia like METRC are so critical for answering big cli…

In this episode of Under Pressure, host Dr. Jonathan Sackier speaks with Mr. Dafydd “Taff” Edwards, Consultant Orthopaedic Trauma Surgeon, Clinical Director, and former Army surgeon whose career spans conflict zones, UK major trauma centres, and cutting-edge elective upper limb surgery. Mr. Edwards…