ABOUT THIS PODCAST 🔗
Unscripted with Jeff Pedowitz is a series of honest, long-form conversations with remarkable people from very different worlds: security and science, business and medicine, technology and the arts. The subject is artificial intelligence and where it's taking us, but every episode gets past the headlines to what these people actually think, have built, and have gotten wrong. AI is the focus for now. The bigger thread is the ideas, decisions, and people shaping what comes next.
Hosts:
Update frequency:
every 4 days
Average audio length:
35 minutes
Guest interviews
English
United States
25 episodes
since June 25, 2026
episodic
LATEST EPISODE 🔗
"I've been to space. I've seen Earth from the outside.
And I'm more worried about what's happening down here than anything I saw up there."
Colonel Terry Virts has flown 40 combat missions, piloted the Space Shuttle, commanded the International Space Station, directed a documentary, and earlier t…
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PREVIOUS EPISODES 🔗
Charlotte Duncan has been teaching AI since 2018 — before most people knew they should care. She wrote the first AI course in North Carolina. She helped build the first national K-12 AI guidelines. She trained at MIT. And then Mark Cuban called.
As Chief Learning Officer at the Mark Cuban Foundati…
Nico Ianeselli wanted to be a doctor like his father until he heard it took 11 years, so he earned dual master's degrees in engineering and architecture instead. In this conversation with Jeff Pedowitz, the Chen Moore and Associates technology chief explains why construction's slowness isn't resist…
Jennifer Preston is a biomedical engineer with a PhD who now leads AI strategy for the consultants shaping drug development and commercialization decisions across pharma and biotech. Her firm uses AI to create synthetic patients and synthetic physicians, digital stand-ins that get interviewed and s…
Matthew Guggemos spent more than 20 years as a speech-language pathologist teaching children to communicate — kids for whom language doesn't come free — and now builds AI at scale as CTO of iTherapy, the company behind InnerVoice, an AAC app with over 50,000 users. He's also a conservatory-trained …
Camberley Bates has spent 30-plus years as one of enterprise technology's most respected independent analysts, paid to cut through vendor hype and tell executives what's real. On this episode of Unscripted, she and Jeff unpack what IBM's earnings dip really signals (AI infrastructure spending delay…
Russ Wilcox, CEO of ArtifexAI, went from a broken sewer decision in his Cape Cod hometown to advising the Pentagon and State Department on the US-China AI race. In this episode of Unscripted, he tells Jeff how mining boring public records, zoning codes, meeting minutes, and permit archives, unlocks…
Every impressive AI demo sits on an enormous, expensive, and very unglamorous foundation of data. Keith Pijanowski is one of the people who built it. After a decade-plus at Microsoft (where he helped evangelize Azure before its public release) and data pipeline work at BNY Mellon, he now works on t…
Everyone is promising humanoid robots in every home and factory. Klas Nilsson has spent 40 years on the part that turns out to be hard. The Cognibotics founder, who built one of the first digital robot motion control systems at ABB in the 1980s, explains why less than 1% of the world's work is done…
Lena Smart has spent 30 years securing the systems we genuinely cannot afford to have fail — the power grid, financial markets, and as longtime CISO at MongoDB, one of the most widely used databases on the planet. She's defended more high-stakes infrastructure than most people will ever see. And sh…
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