ABOUT THIS PODCAST 🔗
Dr. Buck Joffrey sits down with leading scientists in the field of longevity to explore cutting-edge research, emerging therapies, and what it really takes to live longer—healthier.
Hosts:
Update frequency:
weekly
Average audio length:
33 minutes
English
United States
171 episodes
since May 19, 2023
episodic
LATEST EPISODE 🔗
In this episode, we are joined by Dr. Judith Frydman to explore proteostasis: the tightly regulated systems that ensure proteins are correctly folded, maintained, and cleared before they become toxic.
As these systems degrade with age, misfolded proteins accumulate, cellular signaling falters, and…
SEARCH PAST EPISODES
Search past episodes of Longevity Roadmap.
PREVIOUS EPISODES 🔗
Over the past year, we covered a wide range of ground—from clinicians working directly with patients to top scientists studying the underlying biology of aging. This episode is a chance to look back at some of the more interesting conversations we had on Longevity Roadmap in 2025.
Looking ahead, t…
Aging is usually linked to size, metabolism, and inevitable decline—but bats defy all three.
In this episode, Dr. Buck Joffrey speaks with Dr. Emma Teeling about why bats are rewriting the rules of longevity science.
The discussion explores how bats live far longer than expected for their size wh…
Longevity medicine is moving beyond symptom management—and regenerative therapies are forcing a deeper look at how healing actually works.
In this episode, Dr. Buck Joffrey speaks with the team at BioXcellerator about what separates rigorous regenerative medicine from hype-driven shortcuts.
The c…
Aging begins when cellular quality-control systems lose their precision.
In this episode, Professor Ana Maria Cuervo outlines how chaperone-mediated autophagy (CMA)—a selective lysosomal degradation pathway essential for proteostasis—progressively declines with age, triggering downstream failures …
In this episode, we are joined by Dr. Tony Wyss-Coray to discuss his groundbreaking research on brain resilience and aging.
He explains how systemic factors, particularly proteins in the blood, influence cognitive function and the aging process.
The discussion covers the role of proteomics, machi…
In this episode, we are joined by Dr. Francisco González-Lima to delve into the metabolic mechanisms that drive brain aging and cognitive decline.
He begins by outlining how reductions in cytochrome oxidase activity, disruptions in oxidative phosphorylation, and the accumulation of mitochondrial m…
We are joined by behavioral epidemiologist Dr. Kate Wolin to unpack why so many health interventions collapse outside the lab—and what actually drives lasting change in the real world.
From frictionless habit design and daily self-monitoring to movement, sleep, and the muscle-preserving realities …
In this episode, we are joined by Dr. Jennifer Elisseeff to discuss the evolving field of tissue engineering and its applications in regenerative medicine.
She explains the shift from using stem cells to focusing on immune cells for tissue repair, the challenges of regenerating cartilage, and the …
Dr. Heidi Tissenbaum, a molecular geneticist at UMass Chan Medical School, joins Dr. Buck Joffrey to explore what C. elegans worms have revealed about the biology of aging.
She explains how these simple organisms helped uncover key longevity pathways—like insulin/IGF-1 signaling and sirtuins—that …
Disclaimer: The podcast and artwork embedded on this page are from Buck Joffrey, which is the property of its owner and not affiliated with or endorsed by Listen Notes, Inc.
PODCAST SEARCH ENGINE
You can use our website to search 3,831,485 podcasts and 196,819,601 episodes by people, places, or topics.
If I have seen further than others, it is by listening to podcasts and standing upon the shoulders of
giants.
‐ Isaac "Llamacorn" Newton
SEARCH PAST EPISODES
Search past episodes of Longevity Roadmap.
CLAIM THIS PODCAST
Why to claim podcasts?
If you are a podcaster, the best way to manage your podcasts on Listen Notes is by claiming your Listen Notes
podcast pages.
It is a great, free way to engage the podcast community and increase the visibility of your podcasts.
After claiming your Listen Notes podcast pages, you will be able to:
✓
Manually refresh the RSS feed to sync up
✓
Get a verified badge (
✓
) alongside with your podcast name on Listen Notes
✓
Post classified ads for sponsorship,
guests, co-hosts,
cross-promotion...
✓
Respond to listener comments on Listen Notes
✓
Use speech-to-text techniques to transcribe your show and
edit transcripts
✓
Improve the presence of your podcasts, e.g., self-service
podcaster interview...
✓
If you share your Listen Notes page and at-mention @ListenNotes
on X (formerly Twitter),
our official X (formerly Twitter) account will retweet to promote
your show to our followers.
Coming soon:
◯ Self-service promotion on Listen Notes
◯ Track your podcast stats on Listen
Notes, e.g., listens, page
views...
◯ Manage episodes
EDIT
Thank you for helping to keep the podcast database up to date.
