ABOUT THIS PODCAST 🔗

Update frequency:
every 9 days
Average audio length:
27 minutes
English
United States
45 episodes
since June 18, 2025
episodic

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GRAIL Galleri Test Advances at FDA; PAMA Cuts Threaten Lab Margins In this episode, we discuss two major developments affecting laboratory medicine: GRAIL's Galleri multi-cancer early detection test moving closer to FDA approval, and proposed Medicare reimbursement cuts that could significantly imp…

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Episode: Recent Publications and Our Lab Inspection Debrief Episode Summary In this episode, Dr. Zahner and Dr. Aakash dive into their recent article in The Pathologist, "The Vanishing Middle," exploring the growing structural squeeze between centralized mega-labs and decentralized point-of-care fa…
The Human Side of DMT: Trust, Fragility, and Why "Prove It" Kills Progress Dr. Laposata on the interpersonal realities behind diagnostic management teams — why trust matters, why clinicians engage, and what holds DMTs back from wider adoption. Episode Summary Dr. Laposata shifts the conversation f…
1. The Origin Story — Why Coagulation? Coagulation became the natural birthplace of DMTs because hematology was merging with oncology in the 1980s, leaving bleeding disorders to pathology. This created a perfect storm: clinicians didn’t understand coagulation tests, but needed them urgently. The g…
# Why 95%? The Statistical Convention Behind Reference Intervals — and Why It Misleads Patients ## SummaryChris and Dr. Aakash explain how the 95% reference interval became the standard in laboratory medicine — not from physiology, but from a statistical convention borrowed from astronomy. They sho…
# CMS Proposes Revaluing 88305 RVUs After Maryland Claims Analysis ## SummaryCMS is reconsidering RVUs for pathology codes 88305 and 88307 after the Maryland Health Care Commission analyzed 2023 all-payer claims data using CMS's own 25-minute intraservice time assumption. The analysis found 1,763 p…
# ADLM Signals, Cyclospora Surges, and CLIA Redraws the Lab ## SummaryChris and Aakash break down three major signals from ADLM 2026: simultaneous centralization of high-throughput systems and decentralization of point-of-care testing, AI shifting from demos to implementation reality with data infr…
What is Disruption in the LaboratoryDefining disruption requires looking at workflow and ROI rather than just technical novelty. SummaryMarket disruption in the lab is not automatically signaled by new technologies or game-changing results. True disruption addresses underlying economic, workflow, a…
# After the Cookout: Parasites, Pneumonia, and the Lab’s Summer Surge ## SummaryThe conversation covered outbreaks like Cyclosporiasis and Legionnaires Disease, showing how laboratory testing connects to public health investigations. It also discussed the need for better data integration within lab…
DMT Defined Defining what a DMT is and what it is not. Summary The discussion focuses on defining Diagnostic Management Teams (DMTs) by emphasizing that a true DMT must be expert-driven, patient-specific, and aim to establish a single diagnosis in the context of the patient's illness. It contrasts …
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