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We pull apart the twisting strands of the science and technology of life itself - from the very first person to hold up a tube of purified DNA in the thick stone walls of a German castle in the 1860s to the revolution of gene editing that sent shockwaves around the world in the 2010s. The history of biotechnology offers us the chance to understand what it takes to change the world.
Presentadores:
Frecuencia de actualización:
every 18 days
Duración media del audio:
31 minutes
Inglés
Estados Unidos
19 episodios
desde 4 de agosto de 2025
episodic
ÚLTIMO EPISODIO 🔗
A short episode to give you a sense of what to expect from this season.
References
https://www.the-independent.com/news/the-strange-case-of-the-rats-the-coverup-and-a-political-hot-potato-1071126.html
https://en.wikipedia.org/wiki/Pusztai_affair
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EPISODIOS ANTERIORES 🔗
A quick update on what to expect from Season 2 and when to expect it.
What is CRISPR-Cas9 and how is it going to revolutionize the world of GMO crops?
References
de Lange, O., Binder, A. and Lahaye, T. (2014), From dead leaf, to new life: TAL effectors as tools for synthetic biology. Plant J
→ Review article on TAL effectors by yours truly
Ishino Y, Shinagaw…
From glowing petunias to purple tomatoes - this episode is a roundup of some of the lesser known GMO crops that are nonetheless out there in our world.
Key references
Glowing plants
I Bought a Glowing Plant. It Led Me Down a Rabbit Hole. Scientific American. 2024
Glowing Plant US Patent
…
From glowing fish to feminizing tofu - the second and final installment of me answering your questions about GMO.
References relevant to Question 1 - Soy Phytoestrogens
Article on use of the term “Soy boy”
Messina, M., Mejia, S. B., Cassidy, A., Duncan, A., Kurzer, M., Nagato, C., … Barnes, S.…
Why did Monsanto take a canadian farmer all the way to the supreme court? And what does this have to do with controversial herbicide glyphosate?
Learn about the science and history of Round Up Ready GMO crops.
Key references
https://decisions.fct-cf.gc.ca/fc-cf/decisions/en/item/38991/index.do
→…
The NewLeaf potato was a failure, appearing and disappearing in under a decade. But it was the first of a new wave of GMO crops that have endured to the present day - Bt crops.
Key references
Insect Resistance in Crops: A Case Study of Bacillus thuringiensis (Bt) and its Transfer to Developing…
How one tomato changed the world? Or was it two? And what is a GMO tomato anyway. Slice into the story of the FlavrSavr tomato.
Key references
Grierson D. Identifying and silencing tomato ripening genes with antisense genes. Plant Biotechnol J. 2016 Mar;14(3):835-8. doi: 10.1111/pbi.12463. Epub…
From hacking bacteria to blasting your way into the heart of the cell, in this episode we explore the ways to get a transgene into a plant cell and go from there to a whole genetically engineered plant.
Key references
Herrera-Estrella L. My journey into the birth of plant transgenesis and its …
How did a few labs in the San Francisco area transform our relationship to life itself?
Guidelines for Hybrid DNA Molecules - Maxine Singer and Dieter Soll - Science, 1973
Potential Biohazards of Recombinant DNA Molecules - Berg et al., Science, 1974
Electron Micrograph of plasmid DNA, 1967
…
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