ABOUT THIS PODCAST 🔗

Hosts:
Update frequency:
daily
Average audio length:
6 minutes
English
United States
120 episodes
since April 27, 2026
episodic

LATEST EPISODE 🔗

In 1922, fourteen-year-old Leonard Thompson was dying of Type 1 diabetes. He was desperately thin, and the treatment keeping him alive was a diet so restrictive it amounted to controlled starvation. Then he received an injection of pancreatic extract. The first attempt did not go well. The extract …

SEARCH PAST EPISODES

Search past episodes of Decoding Disease with Dr. Rue.

PREVIOUS EPISODES

You’ve probably heard that your pancreas makes insulin. But what does “makes insulin” actually mean? It starts with something called preproinsulin, a long chain of amino acids that isn’t ready to do the job yet. Inside a beta cell, that chain is sent to the right place, folded into shape, packaged,…
Inside a tiny cell is an even tinier gate, opening and closing as conditions change. Something so small, yet what happens at that gate can influence a much larger response. In this episode, we explore why this microscopic gate matters and what it reveals about the extraordinary conversation happeni…
Glucose begins to rise in your blood. But how does a single cell know that it’s happening? And how does that tiny cell know it’s time to respond? In this episode, we explore one of the body’s most remarkable sensing systems and what it reveals about the constant conversation happening inside of us.…
Some of the smallest cells in the body carry some of the biggest responsibilities. A tiny population of cells helps determine how we respond to glucose, use energy, and maintain metabolic balance. In this episode, we explore why these cells matter so much and what happens when such a small part of …
Most people think of insulin as the hormone that regulates blood sugar. But that is only one part of a much bigger story. Its influence extends far beyond glucose, affecting how the body uses, stores, and responds to energy. In this episode, we explore what insulin really means for our biology and …
A tiny signal reaches a cell, and what follows can be enormous. One message can trigger a cascade of activity, amplifying that original signal into a much larger cellular response. In this episode, we explore what this amplification means and why something so small can have such a profound effect o…
A message reaches a cell. But how does that message become action? That transition, from receiving a signal to creating a response, is known as signal transduction. In this episode, we explore what signal transduction means and why this constant cellular conversation is fundamental to how our bodie…
Your cells are surrounded by messages. Hormones and other signaling molecules are constantly ringing the doorbell, but not every cell answers every signal. So how does a cell know when a message is meant for it? In this episode, we explore this remarkable cellular conversation and what it reveals a…
If hormones travel throughout the body, why doesn't every cell respond to every hormone? Why can the same signal matter deeply to one tissue and seemingly mean nothing to another? These are the kinds of questions that reveal just how intelligent and selective the human body really is. In this …
Disclaimer: The podcast and artwork embedded on this page are from Rumbidzai Mudzonga, which is the property of its owner and not affiliated with or endorsed by Listen Notes, Inc.