Episode 9: Why Standard Cancer Treatments Fail (And How to Fight Back)
What if the way we’ve been treating metastatic cancer is completely backwards? Dr. Dawn Lemanne, an oncologist who’s revolutionizing treatment resistance, challenges everything standard oncology accepts as inevitable. After decades of failed large randomized trials, she’s proving that resistance ca…
31. Rewiring Risk: Fixing ADHD Decreases Alzheimers, Social Jet Lag Ups Cancer Risk, and a theoretical strategy to treat prostate cancer
Treat ADHD, lower Alzheimer’s risk?
The episode explores emerging evidence that simply having ADD/ADHD raises lifetime Alzheimer’s risk—yet appropriately treating it in adults, often with low-dose stimulants, seems to push that risk back down. How can the same class of drugs be both feared as “brai…
32. Exercise: the good news and ... bad?
In this episode we discuss one of our favorite pasttimes – exercise—and the relationship between exercise and health. Of course it’s no surprise that exercise is recommended for its health benefits, for people at any age and any level of fitness. Dr. Gordon and I both prescribe exercise as one of …
33. Ultra Processed Foods, is there a simple solution?
In today's episode, we explore the controversy regarding ultra-processed foods, starting with an attempt to define just what those are. That's actually not been carefully approached yet. Then we look at the more serious attempts to construct ways to measure and precisely discuss the hazards of ult…
34. Brain Expert Tommy Wood: Retirement is bad for your brain, unless you do THIS!
In today's episode, we have the distinct pleasure of speaking with Dr. Tommy Wood, whose new book, The Stimulated Mind, will be available soon. We explore his concept of developing greater head space. That's not hat size, but rather our cognitive reserves as we head into older age. We talk about th…
35. Hormones Reconsidered: What We Got Wrong About Estrogen, Risk, and Replacement
In this episode, we’re joined by Debra Zaslow—author and storyteller—who shares her personal experience with hormone replacement therapy, including some immediate and unexpected effects that took her by surprise.
From that starting point, we explore several unexpected ideas:
Estrogen alone may re…
36. Andy Baxter: Lift Heavy but Let It Down Easy
In today's episode, we welcome back a familiar and popular guest, Andy Baxter, who has an impressive resume as rower, rowing coach, and particularly insightful rehabilitation specialist. What Dr. Lemanne and I have particularly appreciated about his work is his focus on not just rehabbing an injury…
37. Why Cancer Treatments Stop Working—and How Killing More Cancer Cells Can Make It Worse
Cancer treatment is simple, right?
Kill as many cancer cells as possible, as quickly as possible.
In some cases, that may be exactly the wrong approach.
In this episode, Dr. Dawn Lemanne and Dr. Deborah Gordon explore a surprising idea emerging from evolutionary biology, ecology, and mathematical o…
40. The N-of-1 Revolution: The Future of Medicine Will Be Studying One Person at a Time, with Gary Isaac Wolf
We physicians look outside the patient, to an expensive wearable, high-tech blood tests, or a brain MRI, to provide us with insights we hope we can use to relieve our patient's suffering. But what if some of the most powerful insights come from observations only a patient can make?
Gary Isaac Wolf,…
39. When “RUNNING HOT AND COLD” is a GOOD thing!
In this episode, we explore some surprising benefits of hot and cold, including sauna, but also the heat of exercise, and one very surprising types of beneficial heat exposure. We start with the remarkable story of a man with an inherited mutation that gave him an extraordinarily high likelihood of…
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