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Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.21.352724v1?rss=1
Authors: Anderies, B. J., Yee, S. F., Jackson, P. R., Rickertsen, C. R., Hawkins-Daarud, A. J., Johnston, S. K., Clark-Swanson, K. R., Hoxworth, J. M., Le, Y., Zhou, Y., Pepin, K. M., Massey, S. C., Hu, L. S., Huston, J. R., Swanson, K. R.
Abstract:
Gliomas are brain tumors characterized by highly variable growth patterns. Magnetic resonance imaging (MRI) is the cornerstone of glioma diagnosis and management planning. However, glioma features on MRI do not directly correlate with tumor cell distribution. Additionally, there is evidence that glioma tumor characteristics and prognosis are sex-dependent. Magnetic resonance elastography (MRE) is an imaging technique that allows interrogation of tissue stiffness in-vivo and has found utility in the imaging of several cancers. We investigate the relationship between MRI features, MRE features, and growth parameters derived from an established mathematical model of glioma proliferation and invasion. Results suggest that both the relationship between tumor volume and tumor stiffness as well as the relationship between the parameters derived from the mathematical model and tumor stiffness are sex-dependent. These findings lend evidence to a growing body of knowledge about the clinical importance of sex in the context of cancer diagnosis, prognosis and treatment.
Copy rights belong to original authors. Visit the link for more info
http://biorxiv.org/cgi/content/short/2020.11.21.352724v1?rss=1
Authors: Anderies, B. J., Yee, S. F., Jackson, P. R., Rickertsen, C. R., Hawkins-Daarud, A. J., Johnston, S. K., Clark-Swanson, K. R., Hoxworth, J. M., Le, Y., Zhou, Y., Pepin, K. M., Massey, S. C., Hu, L. S., Huston, J. R., Swanson, K. R.
Abstract:
Gliomas are brain tumors characterized by highly variable growth patterns. Magnetic resonance imaging (MRI) is the cornerstone of glioma diagnosis and management planning. However, glioma features on MRI do not directly correlate with tumor cell distribution. Additionally, there is evidence that glioma tumor characteristics and prognosis are sex-dependent. Magnetic resonance elastography (MRE) is an imaging technique that allows interrogation of tissue stiffness in-vivo and has found utility in the imaging of several cancers. We investigate the relationship between MRI features, MRE features, and growth parameters derived from an established mathematical model of glioma proliferation and invasion. Results suggest that both the relationship between tumor volume and tumor stiffness as well as the relationship between the parameters derived from the mathematical model and tumor stiffness are sex-dependent. These findings lend evidence to a growing body of knowledge about the clinical importance of sex in the context of cancer diagnosis, prognosis and treatment.
Copy rights belong to original authors. Visit the link for more info
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ค้นหาตอนที่ผ่านมาของ PaperPlayer biorxiv biophysics
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Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.18.388561v1?rss=1
Authors: Medina, L., Gonzalez Lizarraga, F., Dominguez Meijide, A., Ploper, D., Parrales, V., Sequeira, S., Cima Omorri, M. S., Zweckstetter, M., del Bel, E., Michel, P. P., Fleming Outeiro, T., Raisman-Vozari, …
Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.19.390005v1?rss=1
Authors: van Krugten, J., Danne, N., Peterman, E. J. G.
Abstract:
Sensing and reacting to the environment is essential for survival and procreation of most organisms. Caenorhabditis elegans senses soluble chem…
Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.18.388066v1?rss=1
Authors: Longhan, X., Wang, Z., Huang, G., Liu, B., Zhou, Z., Liang, B., Liu, Y.
Abstract:
Lower limb assistive robots have a wide range of applications in medical rehabilitation, hiking, and the military. The…
Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.18.388843v1?rss=1
Authors: Van Oort, C. M., Ferrell, J. B., Remington, J. M., Wshah, S., Li, J.
Abstract:
Antibiotic resistance is a critical public health problem. Each year ${sim}2.8$ million resistant infections lead to more…
Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.18.389106v1?rss=1
Authors: Jetta, D., Bahrani Fard, M. R., Sachs, F., Munechika, K., Hua, S. Z.
Abstract:
Adherent cells utilize local environmental cues to make decisions on their growth and movement. We have previously shown …
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