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𧎠Rare Variant, Real Risk: EGFR T790M and Lung Cancer
Can lung cancer risk be inheritedâeven in never-smokers? ðŦð
In >3.3 million individuals, germline EGFR T790M was rare (~1 in 15,850) but strongly associated with lung cancer (OR 25.18). The association was particularly striking among never-smokers, and the variant showed remarkable lung-cancer specificity. A Southern Appalachian founder effect also revealed how genes, geography & history can converge on modern disease risk. ðšïļð§Ž
ðĄ A compelling case for refining genetic risk assessment and future targeted screening strategies.
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ðð Myths, Metaphors & Magic: Meet Anne Carson, the 2026 Nobel Literature Laureate!
What happens when ancient Greek myths meet modern love, grief, and imagination? âĻ
Canadian poet Anne Carson has reinvented literature by blending poetry, storytelling, and classical scholarship.
ð Three masterâĶ
ð What can physicians learn from the 2026 Economics Nobel?
Robert E. Hall and Michael Woodford transformed macroeconomics by looking beneath the headline numbersâto the decisions and expectations of households and businesses.
ð§ The lesson feels remarkably clinical: diagnose before you treat.
A dâĶ
ðĨ Protein in India: Myths, Meals & Muscle
Are claims of widespread protein deficiency overlooking calories and food quality? Anura Kurpad and Harshpal Singh Sachdev's newspaper article examines this debate.
ðŠ Its calorie-based estimates translate to ~45 g/day for active adults and up to 60 g/âĶ
ððŧ Ghost Particles, Frozen Ice & Cosmic Secrets!
What if a cubic kilometer of Antarctic ice could unlock the universe's deepest mysteries? ðâïļ
The 2026 Nobel Prize in Physics honors Francis Halzen for pioneering IceCube, a giant observatory that detects elusive neutrinosâtiny particles that tâĶ
𧎠Can your T cells reveal how well you're aging?
A remarkable Immunity study integrated 2,609 people and >12 million cells across 8 cohorts. Researchers identified divergent CD8+ effector-memory T-cell trajectories: a higher GZMK+/GZMB+ ratio tracked healthier aging, while GZMB+ cells were linkâĶ
āļāđāļāļŠāļāļ§āļāļŠāļīāļāļāļīāđ: āļāļāļāđāļāļŠāļāđāđāļĨāļ°āļāļēāļĢāđāļāđāļ§āļīāļĢāđāļāļāļĩāđāļāļąāļāļāļĒāļđāđāđāļāļŦāļāđāļēāļāļĩāđāļĄāļēāļāļēāļ Dr RR Baliga, MD, MBA āļāļķāđāļāđāļāđāļāļāļĢāļąāļāļĒāđāļŠāļīāļāļāļāļāđāļāđāļēāļāļāļāđāļĨāļ°āđāļĄāđāļĄāļĩāļŠāđāļ§āļāđāļāļĩāđāļĒāļ§āļāđāļāļāļŦāļĢāļ·āļāļĢāļąāļāļĢāļāļāđāļāļĒ Listen Notes, Inc.
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