Decoding Omega-3 Benefits: A Discussion with the Godfather of Functional Medicine, Part 1

Fish Oil, Full-Spectrum Omega-3s, and Immunometabolism with Dr. Jeffrey Bland: Dr. Ronald Hoffman interviews Dr. Jeffrey Bland, founder of the Personalized Lifestyle Medicine Institute and Big Bold Health, about fish oil and omega-3 science. Bland recounts becoming involved with commercial fish oil in 1980 while promoting MaxEPA amid the “fat is bad” era and discusses Greenland Inuit research showing high omega-3 blood levels and low heart disease. They contrast whole-food omega-3 intake with highly refined EPA/DHA products, highlighting additional constituents in minimally processed oils (vitamins A and D, astaxanthin) and precursor compounds related to specialized pro-resolving mediators. Bland describes Omega-3 Rejuvenate’s Alaska line-caught sourcing and low-heat, chemical-free processing, and addresses concerns about mercury, microplastics, and vitamin A dosing. The conversation also covers PLMI’s focus on immunometabolism, a CBC-derived SIRI marker, omega-3 insufficiency data from Fullscript, mitochondrial membrane support by DHA, and Bland’s upcoming book, “The Nourished Gene.”