Building Impact Through Science and Investment with Jessica Karr, Founder of Coyote Ventures

Join me for an inspiring conversation with Jessica Karr, the heart-centered venture capitalist and founder of Coyote Ventures, who is transforming women's health and wellness through strategic investments. Jessica's journey from biochemist to early team member at Impossible Foods to launching her own impact-focused venture fund is a masterclass in following your values while building wealth.

In this episode, Jessica shares her unconventional path from working in her father's dental practice in Amarillo, Texas, to becoming a force in Silicon Valley venture capital. You'll hear how she navigated stock options as an early employee, the pivotal moments that shaped her investment philosophy, and why she chose to focus exclusively on companies advancing women's health and wellness.

Jessica opens up about the realities of raising a first fund, living capital-efficiently to play the long game, and why being "all in" on private markets aligns with her values—even when wealth managers cringe. Her story illuminates how scientific thinking, patience, and an unwavering commitment to impact can create both financial returns and meaningful change.

Key Topics:

1. Finding alignment between science, sustainability, and personal health through early experiences in healthcare
2. Navigating stock options and secondary markets as an early Impossible Foods employee
3. Transitioning from consulting to venture capital without traditional training
4. Raising your first fund and securing institutional LPs like Bank of America
5. Living capital-efficiently to enable long-term, high-reward opportunities
6. Building a thesis around women's health and wellness investing
7. Creating community and balance while pursuing ambitious career goals
8. Why being "all in" on private markets reflects living in integrity with your mission

Connect with Jessica Karr online:

Website: https://www.coyote.ventures/

LinkedIn: https://www.linkedin.com/in/jessicarkarr/

Instagram: https://www.instagram.com/hellojesskarr/?hl=en

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