Copper Peptides Explained GHK-Cu, Skincare Routines & Ingredient Conflicts

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Welcome to Where Science Meets Self -Care with
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Ida Fanelli. With over 30 years in beauty and
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wellness and a background in medical science,
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Ida blends clinical knowledge with holistic care.
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Each week, she and her guests share insights
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to help you achieve healthier skin, balanced
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energy, and empowered self -care. Now, here's
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your host, Ida Fi
anelli. Today, we're taking a
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closer look at an element many people just see
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as hardware. A shiny penny or old pipes. But
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copper is actually an essential trace mineral
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that plays a key role in many biological and
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biochemical reactions, including those important
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for healthy skin. When most people hear the word
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copper, they think back to chemistry class and
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the periodic table. Even though elements make
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up everything around us, many people don't realize
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that copper is an essential piece of metal. I
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observed something similar during a manicure.
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A client told me she felt more comfortable when
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it comes into contact with air and moisture.
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Everyone's experience is different and this supports
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many metabolic and physiological processes in
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nearly all tissues. This quick change made her
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want to drink it where the body stores copper.
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Again, her experience is individual and does
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not show a guaranteed effect. You might be surprised
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by how it's distributed. Copper is found throughout
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the body, especially in the liver, muscles, bones,
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and brain. Adults only need a small amount each
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day, and the recommended intake depends on age
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and sex. And this small amount supports some
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of the body's most important cellular functions.
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Let's talk about how copper helps your cells.
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Copper is an essential trace mineral that works
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as a helper for several enzymes involved in normal
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cellular energy metabolism. ATP is the main energy
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carrying molecule that cells use throughout the
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body. Copper sports normal body functions in
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several ways. While electrolytes like sodium
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and potassium help with nerve signalling, copper
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acts as a cofactor for enzymes involved in many
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biological processes, including cellular energy
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metabolism. Getting enough copper supports normal
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function and supports maintaining connective
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tissue, iron metabolism, the nervous system,
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and immune health. Copper is needed for the normal
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function of some antioxic enzymes, such as copper
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containing superoxide dismutase, which is a part
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of the body's antioxidant defence system. Copper
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also supports normal nervous system function.
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Copper plays a role in normal pigmentation. It
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acts as a cofactor for tyrosinase. an enzyme
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that helps produce melanin, the natural pigment
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in your skin, hair and eyes. Tyrosinase helps
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specialized cells called melanocytes make melanin
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from the amino acid tyrosinine. Melanin gives
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your skin its tint, your eyes their colour, and
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determines your natural hair colour. having enough
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copper supports the normal activity of enzymes
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like tyrosinase showing copper's importance in
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pigmentation copper complexes and copper peptides
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are also used in cosmetics depending on the products
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they may help condition the skin and improve
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its texture smoothness and overall appearance
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to understand how vitamin C works it's helpful
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to look at both natural wellness and clinical
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science in holistic health vitamin c is seen
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as part of a mix of plant compounds including
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bioflavonoids and coenzymes with copper also
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playing a role scientifically pure vitamin C
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is called alloscorbic acid Both vitamin C and
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copper support important biological processes,
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such as connective tissue formation, but they
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have different roles and vitamin C does not require
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copper to work. However, getting this chemical
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balance right on the skin can be tricky. L -ascorbic
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acid needs a very acidic pH between 2 .5 and
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3 .5 to be absorbed through the skin. Topical
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vitamin C products must be carefully made with
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the right pH concentration, packaging and ingredients.
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Whether vitamin C and copper -containing products
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work well together depends on their specific
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formulas. What if you want to get this through
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your diet? You'll find high concentrations of
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essential dietary copper in shellfish, seeds
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and nuts, organ meats. wheat bran cereal whole
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grain products and dark chocolate chocolate and
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shellfish are both popular foods and good sources
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of copper but copper's benefits go beyond what
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happens in our bodies as we'll see next the antimicrobial
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shield and the oligodynamic effect Now that
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we have looked at copper's biological role, let's
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explore the antimicrobial properties studied
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in copper -containing materials. This is due
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to a scientific phenomenon called the oligodynamic
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effect. In simple terms, the oligodynamic effect
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means that small amounts of certain metal ions,
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including copper and silver, have demonstrated
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antimicrobial activity under specific conditions.
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These outcomes relate to specific materials and
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exposure conditions and should not automatically
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be interpreted as evidence of a health benefit
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from every copper containing consumer product.
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Historically, humans recognized this long before
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modern medical science even knew what a virus
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or bacteria was. Early traditional practices
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used basic cupric carbonate derived from dark
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green malachite crystals. That dark green color
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is a classic sign of oxidized copper. If you
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look at the periodic table, copper, Cu, silver
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Ag, and gold Au sit in the same vertical group
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and share some chemical characteristics. Although
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their chemical reactivity differs, copper is
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widely recognized for its electrical conductivity
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and its ability to participate in oxidation reduction
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reactions. Metal alloys like brass and bronze
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inherit the same oligodynamic effects. However,
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there's an important detail to remember if you
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want to use this in real life. The antimicrobial
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activity reported for certain copper containing
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surfaces depends on the material, surface condition,
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and environmental conditions. A coating can substantially
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change the interaction between the metal surface
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and the environment. The interaction between
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copper containing surfaces, air, moisture and
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microorganisms can influence surface chemistry
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and the availability of copper ions. If you look
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in the background, you'll see some copper chimes
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I made. They are simulating this exact oxidation
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process, showing how copper naturally tarnishes
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when exposed to the elements. If the metal is
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covered with a clear seal or lacquer, the effect
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is blocked. Now what about silver? The saying,
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born with a silver spoon in their mouth, isn't
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about wealth. It refers to health. Silver has
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a long history of use in household and medical
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contexts. and silver ions have well documented
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antimicrobial properties in specific conditions
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however historical practices should not be seen
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as evidence that silver containing products prevent
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illness health canada has specifically advised
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that colloidal silver and silver salts products
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are not authorized to make health claims and
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has warned consumers about unsubstantiated marketing
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of these products today we know that studies
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have investigated combinations of copper and
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silver ions for antimicrobial activity under
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specific experimental conditions let's look at
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how copper ranks in biocidal strength cuprous
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c plus and cupric c 2 plus copper are different
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oxidation states with different chemical properties.
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Researchers have studied their antimicrobial
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activity under a range of experimental conditions.
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Here is a simulated petri dish simulation showing
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that cupric oxide, cuprous oxide and metallic
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copper can demonstrate different levels of antimicrobial
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activity. their effectiveness can vary depending
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on the form of copper surface characteristics
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the concentration or availability of copper ions
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the microorganism involved and environmental
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conditions copper actively fights bacteria cupric
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ions offer moderate resistance cuprous copper
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shows the highest effectiveness metallic copper
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which is monovalent copper is the least effective
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How is this applied in actual products right
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now? Storing water in copper vessels is an ancient
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practice. Researchers have studied copper surfaces
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for their interactions with microorganisms, although
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results depend on conditions and the specific
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vessel. However, copper vessels should not be
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viewed as a substitute for proper water treatment,
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sanitation, or safe drinking water practices.
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What about textiles and healthcare settings?
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Researchers have studied copper -containing alloys
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for their antimicrobial activity on frequently
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touched surfaces in healthcare settings. Research
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has studied whether these materials may reduce
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microbial contamination under specific conditions.
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Consumer textiles and wearables have exploded
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in popularity. Metal surfaces interact with the
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air, moisture, and the surrounding environment.
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and copper -containing materials can release
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ions under certain conditions. Throughout history,
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specialized copper and bronze alloy tools have
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been used in cosmetic massage practices. When
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used for gentle surface massage, these tools
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can help condition the skin and improve the appearance
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of uneven texture while massage can feel soothing
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on areas with uneven skin or old blemishes cosmetic
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massage tools are intended to improve the outward
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appearance of the skin not to medically treat
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break down or remodel underlying scar tissue
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and now we'll take time for commercial break
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welcome back These material properties have contributed
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to the development of a variety of consumer products
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incorporating copper or other metals. Some consumer
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products using copper and silver containing textile
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fibers because these metals have been studied
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for antimicrobial properties and odor control
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applications. Some copper -containing insoles
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are marketed for their odor control and antimicrobial
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properties. Grounding or earthing shoes use copper's
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electrical conductivity to connect you to the
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earth. You can also support earthing by walking
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barefoot on grass, sand, soil, bare dirt, unsealed
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concrete or brick, and even by swimming in natural
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bodies of water. Health Canada does not establish
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claims that grounding or earthing produces a
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health benefit and should not be presented as
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therapeutic. Copper containing compression garments
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are marketed for athletic and everyday use. I
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visited me for reflexology because he was dealing
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with foot pain. The treatment gave him some short
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-term relief. While I was working on his feet,
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I noticed they looked a bit bluish. Because this
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can happen for many reasons, I suggested he check
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with his health care provider about possible
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circulation problems. I suggested he try copper
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compression socks. Later, he told me the socks
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eased his foot pain, but the pain returned when
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he took them off at night. This was just his
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experience and everyone is different. His story
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does not prove that copper socks or similar products
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treat foot pain. or improve circulation. Some
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specialized dressings and healthcare materials
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incorporate copper -containing components. Wearing
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unsealed raw copper bracelets keeps your skin
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in steady contact with copper ions. I wear these
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bracelets myself and have noticed they help with
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my hand joint discomfort. This is just my own
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observation and does not mean copper bracelets
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relieve joint pain or treat any medical condition.
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The manicure bowl and copper gloves. I observed
00:14:25.690 --> 00:14:28.769
something similar during the manicure. A client
00:14:28.769 --> 00:14:31.730
told me she felt more comfortable while her hands
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soaked in a raw copper bowl. Everyone's experience
00:14:35.870 --> 00:14:38.429
is different and this does not prove copper release
00:14:38.429 --> 00:14:41.590
joint pain. As soon as she took her hands out,
00:14:41.629 --> 00:14:44.830
her pain and stiffness came back. This quick
00:14:44.830 --> 00:14:47.629
change made her want to try copper infused gloves
00:14:47.629 --> 00:14:50.820
at night. Again, her experience is individual
00:14:50.820 --> 00:14:55.039
and does not show a guaranteed effect. It might
00:14:55.039 --> 00:14:58.360
seem like magic, but it's really just chemistry.
00:14:59.159 --> 00:15:03.259
When copper meets air and moisture, it can oxidize
00:15:03.259 --> 00:15:06.899
and release copper ions depending on the material
00:15:06.899 --> 00:15:10.700
and environment. Copper acts as a cofactor for
00:15:10.700 --> 00:15:13.500
several enzymes involved in normal biological
00:15:13.500 --> 00:15:17.779
processes, including antioxidant defense. However,
00:15:17.940 --> 00:15:21.440
just because dietary copper has these roles does
00:15:21.440 --> 00:15:24.679
not mean that using copper on the skin will have
00:15:24.679 --> 00:15:28.440
the same systemic antioxidant effect. Industrial
00:15:28.440 --> 00:15:32.480
and everyday copper formulations. We've covered
00:15:32.480 --> 00:15:35.399
internal health and ancient antimicrobial history.
00:15:35.639 --> 00:15:39.720
Still day -to -day life in the 21st century relies
00:15:39.720 --> 00:15:42.879
on dozens of specialized chemical forms of copper
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that most people interact with without ever realizing
00:15:46.820 --> 00:15:51.159
it. Let's look at some common copper compounds.
00:15:51.980 --> 00:15:55.740
Certain Copper containing compounds and pigments
00:15:55.740 --> 00:15:59.080
have been used in coloring applications, including
00:15:59.080 --> 00:16:02.159
some cosmetic formulations, depending on the
00:16:02.159 --> 00:16:05.179
specific ingredients and pertinent legal requirements.
00:16:06.360 --> 00:16:10.360
Next, copper silicate is utilized heavily in
00:16:10.360 --> 00:16:14.720
high -accuracy optical devices, specialized agricultural
00:16:14.720 --> 00:16:17.960
fertilizers, and industrial -grade paint pigments.
00:16:18.669 --> 00:16:21.509
Different forms of copper show varying levels
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of anti -material effectiveness when disinfecting
00:16:25.190 --> 00:16:28.789
surfaces. Copper oxides are used in a variety
00:16:28.789 --> 00:16:32.149
of industrial and technical applications. They
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exist in two different chemical states, cuprous
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oxide and cupric oxide. They are used as rich
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pigments, agricultural fungicides, and anti -fouling
00:16:45.509 --> 00:16:49.340
marine paints. Furthermore, copper's exceptional
00:16:49.340 --> 00:16:53.620
electrical conductivity makes copper oxides essential
00:16:53.620 --> 00:16:57.840
for semiconductors, solar energy panels, and
00:16:57.840 --> 00:17:02.820
even color -producing fireworks. Next up is copper
00:17:02.820 --> 00:17:06.220
sulfate. which has many uses. Copper sulfate
00:17:06.220 --> 00:17:09.660
has applications in agriculture, animal nutrition,
00:17:09.779 --> 00:17:13.259
and diverse industrial processes. Its property
00:17:13.259 --> 00:17:16.859
and uses depend on the specific formulation and
00:17:16.859 --> 00:17:20.380
application. In the textile and leather industries,
00:17:20.759 --> 00:17:24.359
copper sulfate acts as a color stabilizer during
00:17:24.359 --> 00:17:28.380
dyeing, ensuring fabrics maintain vibrant, durable
00:17:28.380 --> 00:17:33.230
colour over time. However, a major warning for
00:17:33.230 --> 00:17:37.109
builders, active copper causes severe galvanic
00:17:37.109 --> 00:17:40.609
corrosion when it contacts standard metals. Copper
00:17:40.609 --> 00:17:43.329
chloride appears as a brownish yellow powder.
00:17:43.529 --> 00:17:47.730
It is widely used in petroleum refinery, textile
00:17:47.730 --> 00:17:52.349
manufacturing, metallurgy, photography, agricultural
00:17:52.349 --> 00:17:56.009
chemical production, animal feed, fortification,
00:17:56.089 --> 00:18:00.410
and wood preservation. Copper carbonate is used
00:18:00.410 --> 00:18:04.170
for bronze electroplating in aquarium products
00:18:04.170 --> 00:18:07.730
to control algae and may have applications in
00:18:07.730 --> 00:18:11.430
coloring and industrial processes depending on
00:18:11.430 --> 00:18:15.609
the specific compound. Copper gluconate is used
00:18:15.609 --> 00:18:18.609
in dietary supplements and may also be found
00:18:18.609 --> 00:18:22.009
in some cosmetic formulations. In cosmetics,
00:18:22.329 --> 00:18:24.890
its intended role depends on the formulation
00:18:24.890 --> 00:18:30.029
and may include skin conditioning. As for medical
00:18:30.029 --> 00:18:33.569
devices inside the human body, metallic copper
00:18:33.569 --> 00:18:37.910
is used in traditional dental amalgams. Copper
00:18:37.910 --> 00:18:40.690
is also included in certain authorized medical
00:18:40.690 --> 00:18:44.609
devices, including copper-containing intrauterine
00:18:44.609 --> 00:18:48.789
devices. These products are regulated separately
00:18:48.789 --> 00:18:52.890
from cosmetics. Beyond internal devices, topical
00:18:52.890 --> 00:18:56.210
cosmetic formulations containing copper ingredients
00:18:56.210 --> 00:19:00.160
may be formulated. to condition the skin and
00:19:00.160 --> 00:19:03.460
improve the appearance or feel of dry, rough,
00:19:03.539 --> 00:19:07.380
or uneven skin texture. So it's important to
00:19:07.380 --> 00:19:09.880
know the difference. Different copper compounds
00:19:09.880 --> 00:19:13.140
have different properties and safety characteristics.
00:19:13.839 --> 00:19:16.960
Cosmetic ingredients must be evaluated in the
00:19:16.960 --> 00:19:20.019
context of their specific formulation, concentration,
00:19:20.480 --> 00:19:25.359
and planned use. The Skin Care Science of Peptides
00:19:25.880 --> 00:19:28.380
now we are entering the cutting -edge domain
00:19:28.380 --> 00:19:32.619
of cosmetic chemistry peptides people hear the
00:19:32.619 --> 00:19:35.380
word peptide thrown around in beauty commercials
00:19:35.380 --> 00:19:39.099
all the time but what is a peptide chemically
00:19:39.099 --> 00:19:43.559
speaking At its core, a peptide is simply a short
00:19:43.559 --> 00:19:46.920
chain of amino acids linked together by peptide
00:19:46.920 --> 00:19:50.920
bonds. There is no universally applicable biological
00:19:50.920 --> 00:19:55.079
cutoff at which every peptide automatically becomes
00:19:55.079 --> 00:19:59.440
a protein. Terminology varies by scientific context.
00:19:59.859 --> 00:20:03.099
Peptides are commonly used in cosmetic formulations
00:20:03.099 --> 00:20:06.240
intended to condition the skin and improve its
00:20:06.240 --> 00:20:09.950
appearance. Peptides are used in a wide variety
00:20:09.950 --> 00:20:13.390
of cosmetic formulations and are often selected
00:20:13.390 --> 00:20:17.130
for their skin conditioning properties. Individual
00:20:17.130 --> 00:20:20.869
products can differ in formulation and tolerability
00:20:20.869 --> 00:20:24.009
so sustainability depends on the finished product
00:20:24.009 --> 00:20:27.890
and the individual. Peptides have been evaluated
00:20:27.890 --> 00:20:31.069
in cosmetic and scientific literature but the
00:20:31.069 --> 00:20:33.730
safety and performance of a finished cosmetic
00:20:33.730 --> 00:20:37.920
depends on its complete formulation. concentration,
00:20:38.240 --> 00:20:42.519
exposure, and planned use. Let's break down four
00:20:42.519 --> 00:20:46.359
classes of peptides. Signal peptides, carrier
00:20:46.359 --> 00:20:50.380
peptides, neurotransmitter inhibitor peptides,
00:20:50.480 --> 00:20:54.960
enzyme inhibitor peptides. Let's tackle signal
00:20:54.960 --> 00:20:59.039
peptides first. Signal peptides are used in cosmetic
00:20:59.039 --> 00:21:02.359
formulations marketed to improve the appearance
00:21:02.359 --> 00:21:05.180
of fine lines and other visible signs of skin
00:21:05.180 --> 00:21:08.480
aging. two of the absolute rock -star signal
00:21:08.480 --> 00:21:12.200
peptides in modern formulations are palmitoy
00:21:12.200 --> 00:21:14.880
tripeptide one and palmitoy tripeptide seven
00:21:14.880 --> 00:21:19.039
palmitoy tripeptide one consists of three amino
00:21:19.039 --> 00:21:24.099
acid sequences glycine histidine lysine bound
00:21:24.099 --> 00:21:27.920
to a fatty acid chain known as palmitic acid
00:21:29.470 --> 00:21:32.829
Attaching a fatty acid can alter a peptide's
00:21:32.829 --> 00:21:35.609
formulation and skin interaction properties.
00:21:36.349 --> 00:21:39.730
Palmitoyl peptides are commonly used in cosmetic
00:21:39.730 --> 00:21:43.269
formulations intended to condition the skin and
00:21:43.269 --> 00:21:46.170
improve the appearance of fine lines and skin
00:21:46.170 --> 00:21:51.750
texture. Palmitoyl tripeptide 7 features a sequence
00:21:51.750 --> 00:21:56.569
of four amino acids, glycine, glutamine, proline,
00:21:57.119 --> 00:22:00.539
arginine attached to palmitic acid researchers
00:22:00.539 --> 00:22:03.460
have studied palmitoy peptides for their effects
00:22:03.460 --> 00:22:07.400
on skin related pathways these peptides are used
00:22:07.400 --> 00:22:10.519
in cosmetic formulations intended to condition
00:22:10.519 --> 00:22:13.339
the skin and improve the appearance of firmness
00:22:13.339 --> 00:22:17.180
smoothness and fine lines A peptide's ability
00:22:17.180 --> 00:22:19.799
to reach different layers of the skin depends
00:22:19.799 --> 00:22:23.079
on its chemical properties, formulation, and
00:22:23.079 --> 00:22:25.940
delivery system. Cosmetic benefits should be
00:22:25.940 --> 00:22:28.440
described according to the evidence available
00:22:28.440 --> 00:22:32.319
for the specific product. Now let's jump into
00:22:32.319 --> 00:22:36.220
enzyme inhibitor peptides. Some peptides have
00:22:36.220 --> 00:22:39.500
been studied for interactions with enzymes involved
00:22:39.500 --> 00:22:43.319
in skin biology and are used in cosmetic formulations
00:22:43.319 --> 00:22:45.720
to improve the appearance and feel of the skin.
00:22:46.400 --> 00:22:49.460
Claims about decreasing irritation, redness,
00:22:49.460 --> 00:22:51.740
or other skin conditions should be supported
00:22:51.740 --> 00:22:55.039
by evidence appropriate to the specific product.
00:22:55.759 --> 00:22:59.319
Where do we source natural peptides? Soybean
00:22:59.319 --> 00:23:02.720
peptides. Some cosmetic formulations use soy
00:23:02.720 --> 00:23:05.900
derived peptides as skin conditioning ingredients.
00:23:06.680 --> 00:23:09.980
Silk peptides derived from silkworm proteins
00:23:09.980 --> 00:23:13.599
are used in some cosmetic formulations as skin
00:23:13.599 --> 00:23:17.220
conditioning ingredients. Rice peptides extracted
00:23:17.220 --> 00:23:20.319
from grain proteins; rice-derived peptides are
00:23:20.319 --> 00:23:23.460
used in some cosmetic formulations as skin conditioning
00:23:23.460 --> 00:23:27.039
ingredients. combining different cosmetic peptides
00:23:27.039 --> 00:23:30.059
can provide complementary skin conditioning benefits
00:23:30.059 --> 00:23:33.880
including improved appearance of smoothness firmness
00:23:33.880 --> 00:23:36.619
and fine lines and now we'll take time for a
00:23:36.619 --> 00:23:40.500
commercial break welcome back revolutionary copper
00:23:40.500 --> 00:23:47.230
peptides ghkcu and ahkcu Understanding the difference
00:23:47.230 --> 00:23:50.170
between biology and cosmetic use is important.
00:23:50.650 --> 00:23:53.789
Copper has essential roles within the human body,
00:23:53.890 --> 00:23:57.390
but those physiological roles should not automatically
00:23:57.390 --> 00:24:00.390
be credited to a topical cosmetic containing
00:24:00.390 --> 00:24:05.369
a copper ingredient. Cosmetic formulations are
00:24:05.369 --> 00:24:07.750
designed for effects such as cleansing, conditioning,
00:24:08.109 --> 00:24:10.690
moisturizing, and improving the appearance of
00:24:10.690 --> 00:24:14.400
the skin. Laboratory or systemic research can
00:24:14.400 --> 00:24:17.359
provide useful scientific backgrounds. However,
00:24:17.619 --> 00:24:20.579
it does not by itself establish that the same
00:24:20.579 --> 00:24:23.839
effect occurs when an ingredient is applied topically
00:24:23.839 --> 00:24:27.559
in a cosmetic product. As a simplified analogy,
00:24:27.980 --> 00:24:31.660
GHKCU is a copper containing peptide complex
00:24:31.660 --> 00:24:36.299
in cosmetic formulations. It is used as an ingredient
00:24:36.299 --> 00:24:39.680
associated with skin conditioning and a healthier
00:24:39.680 --> 00:24:43.480
looking appearance. It is a well -studied naturally
00:24:43.480 --> 00:24:48.819
occurring tripeptide, short for glycol L -histidyl
00:24:48.819 --> 00:24:53.299
L -lysine. Dr. Lauren Pickett isolated it in
00:24:53.299 --> 00:24:57.900
1973. GHK is a naturally occurring tripeptide
00:24:57.900 --> 00:25:02.000
present in human blood plasma, saliva, and urine.
00:25:02.519 --> 00:25:07.059
When GHK binds with a divalent copper ion, Cu2
00:25:07.059 --> 00:25:12.119
+, it forms GHK -Cu. Laboratory research has
00:25:12.119 --> 00:25:16.579
studied GHK -CU and its interactions with cells
00:25:16.579 --> 00:25:20.019
associated with hair follicles. In cosmetic products,
00:25:20.380 --> 00:25:23.539
copper peptides may condition the scalp and improve
00:25:23.539 --> 00:25:27.059
the appearance and feel of hair. Here's an interesting
00:25:27.059 --> 00:25:30.500
fact. Pure copper metal looks reddish yellow,
00:25:30.720 --> 00:25:35.779
but when a copper ion, Cu2 +, dissolves in a
00:25:35.779 --> 00:25:39.339
water -based peptide solution, it turns bright
00:25:39.339 --> 00:25:43.089
blue. That's why GHK -Cu is often called the
00:25:43.089 --> 00:25:46.269
blue copper peptide. But what happens to our
00:25:46.269 --> 00:25:49.950
natural GHK -Cu levels as we grow older? Some
00:25:49.950 --> 00:25:52.670
research has reported age -related differences
00:25:52.670 --> 00:25:57.710
in circulating GHK -related peptide levels. Reported
00:25:57.710 --> 00:26:00.750
values vary among studies and populations, so
00:26:00.750 --> 00:26:03.170
these outcomes should be considered research
00:26:03.170 --> 00:26:06.210
observations rather than MESAs for predicting
00:26:06.210 --> 00:26:09.500
an individual's skin condition or determining
00:26:09.500 --> 00:26:13.680
that topical GHK -Cu will reverse age -related
00:26:13.680 --> 00:26:17.319
changes. In preliminary test tube and laboratory
00:26:17.319 --> 00:26:20.720
research, scientists have observed remarkable
00:26:20.720 --> 00:26:26.279
cellular pathways associated with GHK -Cu. Researchers
00:26:26.279 --> 00:26:30.799
have investigated GHKCU interactions with various
00:26:30.799 --> 00:26:35.400
biological pathways. In a cosmetic context, these
00:26:35.400 --> 00:26:38.099
outcomes should not be interpreted as proof that
00:26:38.099 --> 00:26:41.059
a topical product produces the same systemic
00:26:41.059 --> 00:26:44.539
or cellular effects observed in laboratory research.
00:26:45.660 --> 00:26:49.619
GHKCU is used in some cosmetic formulations intended
00:26:49.619 --> 00:26:52.339
to condition the skin and improve the appearance
00:26:52.339 --> 00:26:58.009
of hydration, suppleness, and smoothness. Laboratory
00:26:58.009 --> 00:27:01.869
research has studied GHKCU in relation to matrix,
00:27:02.150 --> 00:27:06.269
metalloproteinase, and other processes associated
00:27:06.269 --> 00:27:09.650
with the skin's extracellular environment. These
00:27:09.650 --> 00:27:12.390
findings deliver scientific context which should
00:27:12.390 --> 00:27:15.529
not be presented as proof that a cosmetic product
00:27:15.529 --> 00:27:19.029
prevents collagen or elastin breakdown in people.
00:27:19.740 --> 00:27:22.819
Copper is involved in antioxidant enzyme systems
00:27:22.819 --> 00:27:26.819
in the body, while GHKCU has also been investigated
00:27:26.819 --> 00:27:30.859
in laboratory research related to oxidative processes.
00:27:31.400 --> 00:27:35.960
Research has studied GHKCU in cellular processes
00:27:35.960 --> 00:27:39.440
related to copper, iron, and oxidative biology.
00:27:40.039 --> 00:27:42.579
Laboratory research has studied interactions
00:27:42.579 --> 00:27:47.019
between GHKCU, ferritin, iron -related processes,
00:27:47.240 --> 00:27:51.150
and oxidative chemistry. These outcomes can help
00:27:51.150 --> 00:27:53.750
researchers understand the compound's biochemical
00:27:53.750 --> 00:27:57.609
properties. However, results observed in test
00:27:57.609 --> 00:28:00.730
tube or cellular studies should not be presented
00:28:00.730 --> 00:28:03.829
as evidence that a topical cosmetic protects
00:28:03.829 --> 00:28:06.930
human cells or tissues from oxidative damage.
00:28:07.369 --> 00:28:11.289
Research has assessed whether GHK -CU interacts
00:28:11.289 --> 00:28:14.029
with biological pathways associated with gene
00:28:14.029 --> 00:28:17.740
expression and tissue biology. These outcomes
00:28:17.740 --> 00:28:20.960
remain part of the research literature and should
00:28:20.960 --> 00:28:24.200
not be translated directly into claims that a
00:28:24.200 --> 00:28:27.019
cosmetic product repairs or regenerates tissue.
00:28:27.779 --> 00:28:31.759
Some animal and laboratory studies have investigated
00:28:31.759 --> 00:28:36.099
GHKCU in relation to nervous system and other
00:28:36.099 --> 00:28:39.740
biological processes. Finding from these studies
00:28:39.740 --> 00:28:42.140
should not be interpreted as evidence that a
00:28:42.140 --> 00:28:45.799
topical cosmetic provides pain relief or treatment
00:28:45.799 --> 00:28:49.079
of a health condition in humans. It is important
00:28:49.079 --> 00:28:52.079
to distinguish laboratory and biological research
00:28:52.079 --> 00:28:57.500
on GHKCU from the cosmetic use of a topical formulation.
00:28:58.079 --> 00:29:01.619
A cosmetic product is intended to provide effects
00:29:01.619 --> 00:29:04.240
such as cleansing, conditioning, moisturizing,
00:29:04.359 --> 00:29:08.000
or improving the appearance of the skin. Now
00:29:08.000 --> 00:29:13.819
what about its sister peptide, AHKCU? AHKCU is
00:29:13.819 --> 00:29:17.920
another copper -binding tripeptide made of alanine,
00:29:17.960 --> 00:29:21.599
histidine, and lysine bound to copper. It also
00:29:21.599 --> 00:29:25.359
ranges from bright blue to light blue. AHKCU
00:29:25.359 --> 00:29:28.319
has been studied in connection with hair and
00:29:28.319 --> 00:29:31.000
follicle biology and may be used in cosmetic
00:29:31.000 --> 00:29:34.059
formulations intended to condition the scalp
00:29:34.059 --> 00:29:36.859
and hair and improve their appearance and feel.
00:29:37.710 --> 00:29:40.809
Master class ingredient complex and safety warnings.
00:29:41.849 --> 00:29:45.930
Let's start by putting everything together. How
00:29:45.930 --> 00:29:48.789
to layer copper peptides? How to mix them with
00:29:48.789 --> 00:29:51.730
zinc? Ingredients you must avoid and crucial
00:29:51.730 --> 00:29:55.329
health regulatory warnings. Let's start with
00:29:55.329 --> 00:29:58.109
a rival ingredient that often confuses consumers.
00:29:58.980 --> 00:30:02.599
Argylline is a peptide commonly used in cosmetic
00:30:02.599 --> 00:30:05.559
formulations marketed to improve the appearance
00:30:05.559 --> 00:30:09.700
of expression lines and fine lines. Argylline,
00:30:09.720 --> 00:30:14.359
acetyl hexapeptide 8, belongs to the neurotransmitter
00:30:14.359 --> 00:30:18.559
inhibitor peptide class. It's a synthetic peptide
00:30:18.559 --> 00:30:22.180
composed of six amino acids. Now let's look at
00:30:22.180 --> 00:30:26.920
its mechanism. Argeline is used in subcosmetic
00:30:26.920 --> 00:30:29.859
formulations intended to improve the appearance
00:30:29.859 --> 00:30:33.460
of fine expression lines. Application. Apply
00:30:33.460 --> 00:30:36.380
it non -invasively as a daily topical cream or
00:30:36.380 --> 00:30:40.559
serum. Duration. The visible cosmetic effects,
00:30:40.640 --> 00:30:43.539
if any, depend on the formulation, directions
00:30:43.539 --> 00:30:46.880
for use, and the individual products supporting
00:30:46.880 --> 00:30:51.400
evidence. Results. Argilline may deliver a mild
00:30:51.400 --> 00:30:55.519
smoothing effect of fine expression lines. Now
00:30:55.519 --> 00:30:58.680
let's address zinc versus copper in both nutrition
00:30:58.680 --> 00:31:03.559
and skin care. Dietary competition. In your diet,
00:31:03.579 --> 00:31:07.460
zinc and copper compete for absorption. If you're
00:31:07.460 --> 00:31:09.940
considering supplementing either, speak with
00:31:09.940 --> 00:31:12.559
a health professional about an appropriate ratio
00:31:12.559 --> 00:31:17.009
for your needs. Depletion factors, certain dietary
00:31:17.009 --> 00:31:20.690
patterns, medications, or other factors may affect
00:31:20.690 --> 00:31:25.369
copper absorption or copper status. Anyone concerned
00:31:25.369 --> 00:31:28.750
about copper intake or nutritional status should
00:31:28.750 --> 00:31:31.410
discuss their individual circumstances with a
00:31:31.410 --> 00:31:34.970
qualified health care professional. Wilson's
00:31:34.970 --> 00:31:38.009
disease is a medical issue involving copper metabolism.
00:31:38.839 --> 00:31:42.960
People diagnosed with Wilson's disease must follow
00:31:42.960 --> 00:31:45.859
their health care professional's dietary and
00:31:45.859 --> 00:31:50.000
treatment recommendations rather than changing
00:31:50.000 --> 00:31:53.519
their copper intake on their own. Zinc and copper
00:31:53.519 --> 00:31:56.420
have different chemical properties and compatibility
00:31:56.420 --> 00:32:00.740
can vary between formulations. Rather than assuming
00:32:00.740 --> 00:32:03.420
that all zinc and copper peptide products are
00:32:03.420 --> 00:32:06.359
incompatible, follow the manufacturer's directions
00:32:06.359 --> 00:32:09.519
and consider the formulation as a whole. Here's
00:32:09.519 --> 00:32:12.339
one example of a cosmetic skincare layering routine.
00:32:13.759 --> 00:32:16.960
Morning Routine Cosmetic Skin Conditioning and
00:32:16.960 --> 00:32:21.000
Protection Cleanse your face. Start with a fresh
00:32:21.000 --> 00:32:24.700
canvas. Apply a zinc -containing cosmetic serum
00:32:24.700 --> 00:32:28.259
as directed by the manufacturer. depending on
00:32:28.259 --> 00:32:30.740
the formulation it may condition the skin and
00:32:30.740 --> 00:32:33.240
improve the appearance of texture and coloration
00:32:33.240 --> 00:32:37.619
pair with vitamin c or niacinamide vitamin c
00:32:37.619 --> 00:32:40.380
is commonly included in cosmetic formulations
00:32:40.380 --> 00:32:43.440
intended to improve the appearance of skin brightness
00:32:43.440 --> 00:32:48.180
and uneven whether it is appropriate to combine
00:32:48.180 --> 00:32:51.200
it with a particular zinc containing product
00:32:51.200 --> 00:32:55.119
depends on the individual formulation niacinamide
00:32:55.119 --> 00:32:58.240
is commonly used in cosmetic formulations to
00:32:58.240 --> 00:33:00.539
condition the skin and improve the appearance
00:33:00.539 --> 00:33:04.559
of texture and uneven tone moisturize and sunscreen
00:33:04.559 --> 00:33:08.630
lock it in Note that while peptide products are
00:33:08.630 --> 00:33:11.789
cosmetic and help condition and smooth the appearance
00:33:11.789 --> 00:33:15.109
of skin, they do not replace daily skincare and
00:33:15.109 --> 00:33:19.210
appropriate sun protection practices. Night Routine
00:33:19.690 --> 00:33:22.329
cleanse your face apply copper peptide serum
00:33:22.329 --> 00:33:27.369
ghkcu apply your ghkcu copper peptide serum as
00:33:27.369 --> 00:33:30.630
directed by the product manufacturer some cosmetic
00:33:30.630 --> 00:33:33.210
formulations use copper peptides to condition
00:33:33.210 --> 00:33:35.450
the skin and improve the appearance of texture
00:33:35.450 --> 00:33:39.549
and smoothness pair with niacinamide
00:33:39.549 --> 00:33:42.809
is widely used cosmetic formulations to support
00:33:42.809 --> 00:33:44.910
skin conditioning and improve the appearance
00:33:44.910 --> 00:33:48.269
of hydration uneven tone and visible skin texture
00:33:48.990 --> 00:33:52.349
lock it in with a barrier moisturizer the ultimate
00:33:52.349 --> 00:33:55.930
night routine advanced pairing cleanse your face
00:33:55.930 --> 00:34:00.009
always start with a completely fresh canvas apply
00:34:00.009 --> 00:34:04.170
copper peptide serum ghkcu after cleansing as
00:34:04.170 --> 00:34:07.789
directed by the product manufacturer Pair with
00:34:07.789 --> 00:34:11.489
hyaluronic acid or sodium hyaluronate. Hyaluronic
00:34:11.489 --> 00:34:14.489
acid is a humectant commonly used in cosmetic
00:34:14.489 --> 00:34:17.409
formulations to help increase and maintain the
00:34:17.409 --> 00:34:20.349
skin's surface hydration. Sodium hyaluronate
00:34:20.349 --> 00:34:23.110
is a form of hyaluronic acid used in cosmetic
00:34:23.110 --> 00:34:26.070
formulations to help improve the skin's moisture
00:34:26.070 --> 00:34:28.809
content and the appearance of suppleness and
00:34:28.809 --> 00:34:32.110
smoothness. Its behaviour in skin depends on its
00:34:32.110 --> 00:34:35.500
molecular characteristics and formulation. Cosmetic
00:34:35.500 --> 00:34:39.079
formulations containing sodium hyaluronate are
00:34:39.079 --> 00:34:41.940
commonly used for skin conditioning and moisturizing.
00:34:42.519 --> 00:34:45.800
Individual products should be evaluated according
00:34:45.800 --> 00:34:48.880
to their design, directions, and supporting safety
00:34:48.880 --> 00:34:54.219
information. GHKCU and sodium hyaluronate may
00:34:54.219 --> 00:34:57.139
be used together in a cosmetic routine intended
00:34:57.139 --> 00:35:00.159
to condition the skin and improve the appearance
00:35:00.159 --> 00:35:04.670
of surface suppleness and hydration. Pair with
00:35:04.670 --> 00:35:09.469
niacinamide, vitamin B3. Niacinamide is a multifunctional
00:35:09.469 --> 00:35:12.269
cosmetic ingredient commonly used in formulations
00:35:12.269 --> 00:35:14.849
intended to improve the appearance of skin texture,
00:35:14.989 --> 00:35:19.090
tone, plus visible signs of aging. Pair with
00:35:19.090 --> 00:35:22.670
plant -based retinoid alternatives. Bakchual
00:35:22.670 --> 00:35:25.989
is a plant -derived cosmetic ingredient commonly
00:35:25.989 --> 00:35:28.650
used in formulations intended to improve the
00:35:28.650 --> 00:35:31.329
appearance of fine lines, texture, and other
00:35:31.329 --> 00:35:34.920
visible signs of skin aging. Rosehip seed oil
00:35:34.920 --> 00:35:37.940
additionally nourishes the skin barrier. Both
00:35:37.940 --> 00:35:41.559
are common in cosmetic formulations, but compatibility
00:35:41.559 --> 00:35:45.019
depends on the specific products and their formulations.
00:35:45.539 --> 00:35:50.440
Salon -based electroporation support. Some professional
00:35:50.440 --> 00:35:53.599
cosmetic devices use electrical energy as part
00:35:53.599 --> 00:35:58.860
of topical product application procedures. and
00:35:58.860 --> 00:36:01.460
extent of effect depends on the specific device
00:36:01.460 --> 00:36:05.039
settings formulations and manufacturer's directions
00:36:05.039 --> 00:36:09.019
any representation about the device should remain
00:36:09.019 --> 00:36:12.460
consistent with its proposed use and applicable
00:36:12.460 --> 00:36:16.039
authorization and should be used according to
00:36:16.039 --> 00:36:19.780
the manufacturer's directions. Electroporation
00:36:19.780 --> 00:36:22.280
devices are designed to influence the skin's
00:36:22.280 --> 00:36:25.599
surface properties temporarily and may be used
00:36:25.599 --> 00:36:28.420
in subcosmetic settings as a topical application
00:36:28.420 --> 00:36:33.039
technique when used as intended it is a noninvasive
00:36:33.039 --> 00:36:36.159
cosmetic procedure without needles or intentional
00:36:36.159 --> 00:36:40.340
skin wounding If LED or another cosmetic device
00:36:40.340 --> 00:36:44.199
is incorporated into a skincare routine, follow
00:36:44.199 --> 00:36:46.659
the manufacturer's directions for the specific
00:36:46.659 --> 00:36:50.739
device and products being used. And now we'll
00:36:50.739 --> 00:36:53.920
take time for a commercial break. Welcome back.
00:36:54.360 --> 00:36:57.440
Light -based technology can be discussed from
00:36:57.440 --> 00:37:02.159
both a scientific and cosmetic perspective. But
00:37:02.159 --> 00:37:04.800
those two perspectives should not be confused.
00:37:05.320 --> 00:37:10.429
Red light in... the approximately 630 to 660
00:37:10.429 --> 00:37:14.150
nanometer range is commonly discussed in cosmetic
00:37:14.150 --> 00:37:17.769
light based applications in a cosmetic context
00:37:17.769 --> 00:37:21.030
claims should focus on visible skin appearance
00:37:21.030 --> 00:37:24.309
unless a specific device has authorized therapeutic
00:37:24.309 --> 00:37:29.849
indications near-infrared (NIR) light 800 to 850
00:37:29.849 --> 00:37:33.210
nanometers can interact with tissue differently
00:37:33.210 --> 00:37:36.449
from visible light Research has assessed various
00:37:36.449 --> 00:37:39.030
biological effects, but cosmetic representations
00:37:39.030 --> 00:37:42.510
should remain focused on the appearance and conditioning
00:37:42.510 --> 00:37:45.510
of the skin unless the device has an authorized
00:37:45.510 --> 00:37:50.570
therapeutic indication. Flu light, 450 nanometers,
00:37:50.730 --> 00:37:53.630
has been studied for its interactions with skin
00:37:53.630 --> 00:37:57.050
-associated microorganisms. Claims that a device
00:37:57.050 --> 00:37:59.730
treats blemishes or another skin condition are
00:37:59.730 --> 00:38:03.280
therapeutic claims and should only be made were
00:38:03.280 --> 00:38:06.440
supported by the device authorized indication.
00:38:07.039 --> 00:38:11.500
Green light, 525 nanometers. Wavelengths are
00:38:11.500 --> 00:38:14.119
sometimes discussed in cosmetic light -based
00:38:14.119 --> 00:38:16.519
approaches to the appearance of uneven skin tone.
00:38:16.980 --> 00:38:20.940
Any claim that a device treats a pigment disorder
00:38:20.940 --> 00:38:24.639
or condition would require an appropriate authorized
00:38:24.639 --> 00:38:28.679
therapeutic indication. Yellow or amber light,
00:38:28.880 --> 00:38:32.460
590 nanometers have been studied in various light
00:38:32.780 --> 00:38:36.320
based applications in cosmetic contacts descriptions
00:38:36.320 --> 00:38:39.960
should focus on supported effects on skin's appearance
00:38:39.960 --> 00:38:42.059
rather than claims about treating inflammation
00:38:42.059 --> 00:38:46.780
or promoting wound healing a quick note led session
00:38:46.780 --> 00:38:50.460
durations and frequency vary by device follow
00:38:50.460 --> 00:38:54.300
the manufacturer's directions for use in a cosmetic
00:38:54.300 --> 00:38:57.599
context any claim benefit should be supported
00:38:57.599 --> 00:39:01.000
by evidence appropriate to the specific device
00:39:02.689 --> 00:39:06.650
CoQ10, ubiquinone, and copper are involved in
00:39:06.650 --> 00:39:09.889
different biological processes. In cosmetic formulations,
00:39:10.010 --> 00:39:13.289
products containing these ingredients may condition
00:39:13.289 --> 00:39:16.389
the skin and support the appearance of smoothness
00:39:16.389 --> 00:39:20.150
and firmness. Astaxanthin is a carotenoid with
00:39:20.150 --> 00:39:22.469
antioxidant properties that has been studied
00:39:22.469 --> 00:39:27.090
in cosmetics and nutritional context. C. buckthorn
00:39:27.090 --> 00:39:31.750
oil contains various fatty acids including palmitic
00:39:31.750 --> 00:39:35.159
acid, toluic acid, omega -7, as well as other
00:39:35.159 --> 00:39:37.579
naturally occurring compounds and is used in
00:39:37.579 --> 00:39:40.500
some cosmetic formulations to condition the skin.
00:39:41.480 --> 00:39:46.019
Apply lipid -soluble actives. Because COQ10,
00:39:46.260 --> 00:39:49.460
astaxanthin, and sea buckthorn oil are naturally
00:39:49.460 --> 00:39:52.360
fat-soluble; they are often formulated into
00:39:52.360 --> 00:39:55.960
rich facial serums or botanical oils. You can
00:39:55.960 --> 00:39:59.099
incorporate them into your skincare routine according
00:39:59.099 --> 00:40:02.329
to the formulation's directions. after your water
00:40:02.329 --> 00:40:07.190
-based GHKCU and electroporation steps. Finish
00:40:07.190 --> 00:40:09.329
with a moisturizer appropriate for your skin
00:40:09.329 --> 00:40:12.449
and the manufacturer's directions. Now, what
00:40:12.449 --> 00:40:14.869
should we keep in mind when combining copper
00:40:14.869 --> 00:40:18.090
peptides and other skincare ingredients? Let's
00:40:18.090 --> 00:40:20.190
look at some commonly discussed formulations
00:40:20.190 --> 00:40:23.889
and routine considerations. Vitamin C derivatives.
00:40:24.880 --> 00:40:28.840
Vitamin C is another good example of why an ingredient's
00:40:28.840 --> 00:40:32.239
chemical form matters. Pure vitamin C, also known
00:40:32.239 --> 00:40:36.199
as L -ascorbic acid, is biologically active but
00:40:36.199 --> 00:40:40.360
can be relatively unstable in cosmetic formulations.
00:40:40.400 --> 00:40:43.719
For this reason, skincare products may use different
00:40:43.719 --> 00:40:47.519
vitamin C derivatives such as sodium ascorbyl
00:40:47.519 --> 00:40:51.539
phosphate, magnesium ascorbyl phosphate, ascorbyl
00:40:51.539 --> 00:40:55.920
glucoside, ethyl ascorbic acid, or tetrahexidyl
00:40:55.920 --> 00:40:59.579
ascorbate. These derivatives have different chemical
00:40:59.579 --> 00:41:02.679
properties including differences in water or
00:41:02.679 --> 00:41:07.099
oil solubility and formulation stability. Depending
00:41:07.099 --> 00:41:10.480
on the derivative and formulation, some may convert
00:41:10.480 --> 00:41:14.019
or contribute to vitamin C-related activity in
00:41:14.019 --> 00:41:17.019
the skin. This is why we shouldn't assume that
00:41:17.019 --> 00:41:20.079
every ingredient with vitamin C in its name behaves
00:41:20.079 --> 00:41:24.099
exactly like pure L -ascorbic acid. Some vitamin
00:41:24.099 --> 00:41:27.880
C derivatives are formulated at different pH
00:41:27.880 --> 00:41:31.539
levels and may be compatible with copper peptides.
00:41:31.980 --> 00:41:34.139
Always follow the directions and compatibility
00:41:34.139 --> 00:41:38.139
guidance provided by the manufacturers. Using
00:41:38.139 --> 00:41:41.340
retinol in the same routine. Retinol is a vitamin
00:41:41.340 --> 00:41:44.699
A derivative used in cosmetic and dermatological
00:41:44.699 --> 00:41:47.980
products. Depending on the specific product formulation
00:41:47.980 --> 00:41:52.139
and ethical and legal requirements, it may be discussed
00:41:52.139 --> 00:41:54.599
in relation to the appearance of fine lines,
00:41:54.659 --> 00:41:57.780
texture, and other visible signs of skin aging.
00:41:58.510 --> 00:42:01.949
If irritation occurs, consider alternating products
00:42:01.949 --> 00:42:05.030
or following the manufacturer's recommended routine.
00:42:05.909 --> 00:42:10.730
Split routine, AM -PM. Apply your GHKCU copper
00:42:10.730 --> 00:42:14.510
peptide serum as directed by the product manufacturer.
00:42:14.650 --> 00:42:17.590
Some cosmetic formulations use copper peptides
00:42:17.590 --> 00:42:20.269
to condition the skin and improve the appearance
00:42:20.269 --> 00:42:23.730
of textures and smoothness. Alternate nights
00:42:23.730 --> 00:42:26.849
rotate your products by using your copper peptides.
00:42:27.360 --> 00:42:29.739
serum one night and your retinol the next night
00:42:29.739 --> 00:42:35.920
strong direct acids: AHAs and BHAs
00:42:35.920 --> 00:42:39.079
are exfoliating ingredients used in various cosmetic
00:42:39.079 --> 00:42:42.260
formulations to help improve the appearance and
00:42:42.260 --> 00:42:46.010
texture of the skin some products containing
00:42:46.010 --> 00:42:48.650
these ingredients may fall under different regulatory
00:42:48.650 --> 00:42:52.269
requirements depending on their composition and
00:42:52.269 --> 00:42:56.110
claims. Strong direct acids, including some AHAs
00:42:56.110 --> 00:42:59.289
and BHAs, may not be compatible with every copper
00:42:59.289 --> 00:43:02.929
peptide formulation because product formulations
00:43:02.929 --> 00:43:05.969
vary. Follow the manufacturer's directions and
00:43:05.969 --> 00:43:08.449
consider separating products if recommended.
00:43:08.929 --> 00:43:12.960
Pro tip. If you accidentally use an acidic toner
00:43:12.960 --> 00:43:16.300
before your copper peptide, don't worry. If you
00:43:16.300 --> 00:43:19.079
are using products with different pH ranges,
00:43:19.460 --> 00:43:22.079
follow the manufacturer's directions rather than
00:43:22.079 --> 00:43:26.559
relying on a universal waiting period. Enzyme
00:43:26.559 --> 00:43:29.260
-based exfoliation options, including bromelain
00:43:29.260 --> 00:43:33.019
from pineapples and papain from papaya, can help
00:43:33.019 --> 00:43:35.940
loosen and remove surface corneocytes, leaving
00:43:35.940 --> 00:43:38.739
skin smoother and improving the appearance of
00:43:38.739 --> 00:43:42.139
surface texture. Because mature or reactive skin
00:43:42.139 --> 00:43:44.659
can be more sensitive, select and use enzyme
00:43:44.659 --> 00:43:47.599
exfoliants according to the product directions.
00:43:48.559 --> 00:43:51.679
Enzyme -based cosmetic formulations help improve
00:43:51.679 --> 00:43:54.539
the appearance and feel of surface texture, but
00:43:54.539 --> 00:43:57.739
individual tolerance differences. I'm not recommending
00:43:57.739 --> 00:44:01.280
applying a concentrated enzyme topically as it
00:44:01.280 --> 00:44:04.280
can be aggressive. Only a properly formulated
00:44:04.280 --> 00:44:08.039
product. Whether a formulation changes the delivery
00:44:08.039 --> 00:44:11.119
or stability of another product depends on the
00:44:11.119 --> 00:44:14.340
specific formulation. The regulatory reality.
00:44:14.639 --> 00:44:18.079
When navigating skincare, separate marketing
00:44:18.079 --> 00:44:23.059
buzzwords from regulatory facts, labels like
00:44:23.059 --> 00:44:26.840
medical grade or cosmeceutical are not officially
00:44:26.840 --> 00:44:31.340
recognized categories under Health Canada. Topical
00:44:31.340 --> 00:44:34.500
copper peptides may be used in cosmetic formulations
00:44:34.500 --> 00:44:38.219
for purposes such as skin conditioning and improving
00:44:38.219 --> 00:44:41.239
the appearance of the skin. However, a particular
00:44:41.239 --> 00:44:44.260
product is not classified solely because it contains
00:44:44.260 --> 00:44:48.059
a copper peptide. Health Canada takes into account
00:44:48.059 --> 00:44:50.760
the product's composition, purpose, intended
00:44:50.760 --> 00:44:54.659
use, and representation or claims. Therapeutic
00:44:54.659 --> 00:44:57.219
representations may result in a product being
00:44:57.219 --> 00:45:00.300
classified under a different regulatory framework.
00:45:00.719 --> 00:45:06.199
Cosmetic copper peptides such as GHKCU and AHKCU
00:45:06.199 --> 00:45:10.320
may be used in cosmetic formulations for skin
00:45:10.320 --> 00:45:13.920
conditioning purposes. Whether a particular product
00:45:13.920 --> 00:45:17.139
qualifies as a cosmetic depends on its composition,
00:45:17.480 --> 00:45:21.269
intended use, and the claims made about it. When
00:45:21.269 --> 00:45:24.090
a product is appropriately classified and marketed
00:45:24.090 --> 00:45:28.369
as a cosmetic, its intended function should remain
00:45:28.369 --> 00:45:31.309
within the cosmetic scope. For example, cleansing,
00:45:31.489 --> 00:45:33.610
moisturizing, conditioning, or improving the
00:45:33.610 --> 00:45:37.070
appearance of the skin. Claims involving a therapeutic
00:45:37.070 --> 00:45:40.070
effect or systemic action can change the regulatory
00:45:40.070 --> 00:45:44.309
classification. Topical exosome regulations.
00:45:45.610 --> 00:45:49.329
exosomes are extracellular vesicles that are
00:45:49.329 --> 00:45:51.849
being investigated for a range of biological
00:45:51.849 --> 00:45:56.170
applications the regulatory classification of
00:45:56.170 --> 00:45:58.989
a topical product containing exosomes relies on
00:45:58.989 --> 00:46:02.889
factors including the source composition representation
00:46:02.889 --> 00:46:06.829
and intended level of action in exosome research
00:46:06.829 --> 00:46:09.730
includes investigations into biological pathways
00:46:09.730 --> 00:46:13.820
associated with the skin and tissue biology These
00:46:13.820 --> 00:46:16.239
research findings should not be presented as
00:46:16.239 --> 00:46:18.940
proof that a topical cosmetic regenerates tissue
00:46:18.940 --> 00:46:22.659
or stimulates collagen in people. Health Canada
00:46:22.659 --> 00:46:26.559
has specific regulatory considerations for topical
00:46:26.559 --> 00:46:29.780
products containing human -derived exosomes,
00:46:29.920 --> 00:46:33.659
human extracellular vesicles, or human cells
00:46:33.659 --> 00:46:37.559
conditioned media. Their classification relies
00:46:37.559 --> 00:46:40.960
on factors including the source, composition
00:46:40.960 --> 00:46:45.059
representation and intended level of action and
00:46:45.059 --> 00:46:48.059
cannot be determined simply by describing a product
00:46:48.059 --> 00:46:52.619
as cosmetic injectable peptides and prescription
00:46:52.619 --> 00:46:56.300
status injectable peptides products are not the
00:46:56.300 --> 00:46:59.280
same regulatory category as topical cosmetic
00:46:59.280 --> 00:47:03.650
peptide products In Canada, injectable peptide
00:47:03.650 --> 00:47:06.349
products may be regulated as prescription drugs
00:47:06.349 --> 00:47:09.269
and require appropriate Health Canada authorization
00:47:09.269 --> 00:47:14.090
before sale. Authorized drug products in Canada
00:47:14.090 --> 00:47:17.150
are assigned the applicable Health Canada authorization
00:47:17.150 --> 00:47:20.750
identifier, such as a drug identification number,
00:47:20.889 --> 00:47:25.090
DIN, where required. Do your due diligence and
00:47:25.090 --> 00:47:27.869
note that injectable peptide products have different
00:47:27.869 --> 00:47:30.429
regulatory acceptance in different countries.
00:47:31.690 --> 00:47:34.809
the research only loophole warning calling a
00:47:34.809 --> 00:47:37.809
product for research only does not by itself
00:47:37.809 --> 00:47:41.070
determine its regulatory classification Health
00:47:41.070 --> 00:47:44.190
Canada examines the product's composition purpose
00:47:44.190 --> 00:47:48.519
intended use and representation A label or disclaimer
00:47:48.519 --> 00:47:51.559
should not be relied upon as a substitute for
00:47:51.559 --> 00:47:55.619
appropriate regulatory classification. Consumers
00:47:55.619 --> 00:47:58.320
should be cautious about unauthorized injectable
00:47:58.320 --> 00:48:01.739
products because their identity, purity, sterility,
00:48:01.920 --> 00:48:05.260
concentration, and quality may not be adequately
00:48:05.260 --> 00:48:08.820
established. To move through this space safely,
00:48:09.000 --> 00:48:11.920
always consult a certified healthcare provider
00:48:11.920 --> 00:48:15.599
and source authorized products through regulated
00:48:15.599 --> 00:48:19.300
pharmacies. Do not use unauthorized injectable
00:48:19.300 --> 00:48:22.440
products. Seek advice from a qualified healthcare
00:48:22.440 --> 00:48:25.579
professional or pharmacist regarding appropriate
00:48:25.579 --> 00:48:30.139
handling and disposal. Copper has played an important
00:48:30.139 --> 00:48:33.179
role in our lives, from ancient coins used to
00:48:33.179 --> 00:48:37.000
keep water clean to hospital surfaces. to modern
00:48:37.000 --> 00:48:40.280
blue peptide serums for smoother skin copper
00:48:40.280 --> 00:48:43.840
is important in biochemistry and materials science
00:48:43.840 --> 00:48:47.380
and cosmetics its properties and uses depend
00:48:47.380 --> 00:48:50.559
on its chemical form concentration environment
00:48:50.559 --> 00:48:55.420
and application the value of copper sustainability
00:48:55.420 --> 00:48:59.300
and recycling now we need to talk about the physical
00:48:59.300 --> 00:49:03.320
reality of copper in our modern world as technology
00:49:03.320 --> 00:49:05.880
advances especially with more electrical vehicles
00:49:05.880 --> 00:49:09.360
solar panels and smart electronics the global
00:49:09.360 --> 00:49:12.659
demand for copper has increased making raw materials
00:49:12.659 --> 00:49:17.679
more expensive at the same time people in governments
00:49:17.679 --> 00:49:20.539
are more aware of how mining affects water soil
00:49:20.539 --> 00:49:23.840
and habitats these issues make the copper we
00:49:23.840 --> 00:49:27.539
already have even more valuable One amazing thing
00:49:27.539 --> 00:49:30.099
about copper is that it can be recycled again
00:49:30.099 --> 00:49:33.219
and again without losing its important properties
00:49:33.219 --> 00:49:37.659
like electrical conductivity or strength. Because
00:49:37.659 --> 00:49:40.260
copper is valuable and environmentally friendly
00:49:40.260 --> 00:49:43.920
mining is limited, it's important to reuse what
00:49:43.920 --> 00:49:46.579
we already have. We should think about the full
00:49:46.579 --> 00:49:50.519
life of items that contain copper. This means
00:49:50.519 --> 00:49:53.059
repairing and reusing things like electrical
00:49:53.059 --> 00:49:56.860
tools, electronics, and small appliances whenever
00:49:56.860 --> 00:50:00.260
possible instead of throwing them away. Proper
00:50:00.260 --> 00:50:03.880
disposal is also important when things like batteries,
00:50:04.079 --> 00:50:07.440
old wires, or broken tools can't be used anymore.
00:50:07.940 --> 00:50:11.579
They shouldn't go in the regular trash. Most
00:50:11.579 --> 00:50:14.179
cities have special recycling centers for metals
00:50:14.179 --> 00:50:17.260
and electronic waste to safely recover and reuse
00:50:17.260 --> 00:50:20.320
copper. By recycling, we reduce the environmental
00:50:20.320 --> 00:50:23.699
impact of the mining and help keep copper available
00:50:23.699 --> 00:50:26.719
for future generations, whether for building
00:50:26.719 --> 00:50:30.039
infrastructure or making new skincare products.
00:50:30.920 --> 00:50:34.159
Conclusion. Copper is much more than a common
00:50:34.159 --> 00:50:37.099
industrial metal. It is important in human biology,
00:50:37.300 --> 00:50:40.340
historical sanitation, and modern cosmetic science.
00:50:40.820 --> 00:50:44.300
Copper supports cellular energy and normal pigmentation.
00:50:45.039 --> 00:50:47.940
and it has well -studied chemistry and antimicrobial
00:50:47.940 --> 00:50:51.579
properties under certain conditions. In skincare,
00:50:51.780 --> 00:50:56.579
copper peptides like GHKCU and AHKCU are used
00:50:56.579 --> 00:50:59.780
in some products to condition the skin and improve
00:50:59.780 --> 00:51:03.460
hydration, smoothness, and firmness. Understanding
00:51:03.460 --> 00:51:06.900
copper chemistry and cosmetic formulations helps
00:51:06.900 --> 00:51:09.500
us make better choices about ingredients and
00:51:09.500 --> 00:51:13.659
skincare products. Always consider products compatibility,
00:51:14.340 --> 00:51:17.460
directions for use, and cosmetic claims in the
00:51:17.460 --> 00:51:20.820
context of the specific product. Disclaimer.
00:51:20.920 --> 00:51:23.760
This material is provided for general educational
00:51:23.760 --> 00:51:27.000
and informational purposes only. It is not intended
00:51:27.000 --> 00:51:29.800
to diagnose, treat, cure, or prevent any disease,
00:51:30.059 --> 00:51:33.179
disorder, or medical condition and is not a substitute
00:51:33.179 --> 00:51:37.320
for individual advice from a qualified health
00:51:37.320 --> 00:51:40.420
professional. scientific research discussed in
00:51:40.420 --> 00:51:43.000
this material is provided as educational background
00:51:43.000 --> 00:51:46.019
and should not be interpreted as evidence that
00:51:46.019 --> 00:51:49.079
a particular cosmetic product produces a therapeutic
00:51:49.079 --> 00:51:53.269
pharmacological or systemic effect Evaluate cosmetic
00:51:53.269 --> 00:51:56.530
ingredients and technologies based on their formulation,
00:51:56.869 --> 00:52:00.409
intended use, evidence, representations, and
00:52:00.409 --> 00:52:03.929
applicable legal requirements. Descriptions of
00:52:03.929 --> 00:52:06.670
biological mechanisms are included to explain
00:52:06.670 --> 00:52:09.329
the science behind an ingredient or technology.
00:52:09.769 --> 00:52:12.309
They should not be interpreted as claims that
00:52:12.309 --> 00:52:16.030
a cosmetic product modifies, repairs, restores,
00:52:16.030 --> 00:52:19.679
or treats underlying biological conditions. You
00:52:19.679 --> 00:52:23.840
can view this episode on many platforms. Thank
00:52:23.840 --> 00:52:26.320
you for tuning in to Where Science Meets Self
00:52:26.320 --> 00:52:29.440
-Care with Ida Finelli. Ida bridges clinical
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science with holistic wisdom, guiding you toward
00:52:32.900 --> 00:52:36.579
radiant skin, balanced energy, and lasting well
00:52:36.579 --> 00:52:39.980
-being. Don't forget to subscribe, share the
00:52:39.980 --> 00:52:43.039
show. And join us next time for more inspiration
00:52:43.039 --> 00:52:46.260
and practical tools to help you live beautifully
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inside and out. To connect with Ida, visit linktr.ee
00:52:50.460 --> 00:52:55.780
/idafanelli. Until then, take good care of yourself.
00:52:56.019 --> 00:52:59.400
And remember, self -care is where science and
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soul meet.