ABOUT THIS EPISODE
Sans Thakur, CEO and Chairman of Tower Capital Group, joins Jason Feifer to explain why the longevity industry is missing the point. The real frontier is generational health: the science of how your DNA, environment, and choices create cascades that shape your descendants' health for up to 16 generations.
Sans is one of the named pioneers of generational health. She spent decades helping launch 40+ medicines that reached 6 million patients before becoming an investor. In this conversation, she breaks down what's actually possible right now: dementia prevention infusions that cut risk by 50%, bio-AI that can grow a beating heart from a drop of your blood, and why the food you eat is interacting with your cells in ways science is only beginning to understand.
If you've been skeptical of the longevity hype but curious about what real science can do, this episode is for you.
Disclaimer: The science descriptions are ultra simplified for general audience consumption.
Timestamps:
00:00 Cold open
01:25 Why longevity has become "fluffy" and what it used to mean
02:30 What Tower Capital Group actually does
09:12 Defining generational health and the 16-generation cascade
13:53 From Human Genome Project to today's bio-AI breakthroughs
18:00 The dementia prevention infusion that cuts risk by 50%
21:30 Genetic cascades explained: how your choices imprint on your DNA
24:35 Growing a beating heart from a drop of blood
28:30 Bioethics and why this technology isn't available to everyone yet
29:32 Your mother's mitochondria and why maternal health is underfunded
32:00 Why longevity influencers get it wrong
36:38 Food as medicine and the data gap between groceries and clinics
40:12 How much do we actually know about food and the body?
46:13 How to get involved with Tower Capital Group and Uncharted Pitches
52:48 The "spackle" and why small wins matter too
