ABOUT THIS EPISODE
Pharmaceutical manufacturers working with hazardous and difficult-to-control chemical reactions face challenges in managing process safety, heat transfer, and reaction conditions. Flow chemistry offers an alternative to traditional batch processing in applications where improved mixing, temperature control, and smaller quantities of hazardous materials in the reactor can help reduce operational risks and improve process performance.
In this episode of Off Script, sponsored by Valsynthese, we spoke with Luca Allievi, PhD, R&D Chemist and Project Manager at Valsynthese, about the role of flow chemistry in complex pharmaceutical manufacturing. The conversation explores how flow reactors work, where continuous processing offers advantages over batch production, and how the technology is being applied to azide chemistry, gas-liquid reactions, and highly reactive reagents. Allievi also discusses the practical challenges of implementing flow chemistry and why the future of process development will depend on selecting the right technology for each reaction.