What happens when weight loss is working, but you still need to protect muscle, performance, and long-term health? And how do GLP-1s, testosterone, peptides, nutrition, and training fit into the bigger picture?
In this episode of Earn Your Protocol presented by HollyFit, Kyle Holland and Dr. Michael Harrington answer questions around GLP-1 medications, nutrition, resistance training, testosterone, peptides, recovery, and more.
They discuss how to preserve muscle while losing weight, why treatment should be individualized, where testosterone may fit into women’s health, and why emerging compounds should be approached with both curiosity and caution. The conversation also gets a little lighter when Kyle puts his medical pronunciation skills to the test.
Throughout the episode, Kyle and Dr. Michael return to a simple principle: understand the individual first, then use the right tools to support sustainable health and performance.
Key Takeaways & Lessons:
- Using a GLP-1 and worried about losing muscle? Learn why resistance training, nutrition, protein intake, and rate of weight loss matter.
- Think a higher medication dose is always better? Hear why treatment should be individualized rather than automatically increased.
- Trying to improve body composition? Understand how nutrition and training can help preserve muscle while reducing body fat.
- Not sure how long to rest between sets? Kyle and Dr. Michael discuss hypertrophy, progressive overload, training to failure, and recovery.
- Wondering where testosterone fits into women’s health? Explore the broader conversation around libido, energy, mood, sleep, and perimenopause.
- Curious about peptides and emerging compounds? Hear why enthusiasm can move faster than the available human research.
- How open should you be with your physician? Learn why honest communication matters when discussing medications, supplements, and treatment decisions.
- Think medical terminology is easy? Kyle discovers that some words are much easier to read than pronounce.
Kyle Holland is the founder and Head Coach of HollyFit, where he combines coaching, nutrition, training, and data-driven health optimization to help people build and sustain healthier lives.
Dr. Michael Harrington is a board-certified internal medicine physician and HollyFit’s medical director. He leads clinical evaluations and makes treatment decisions based on each individual’s labs, history, and clinical needs.
Episode Resources:
Episode Highlights:
- [00:29] GLP-1s, Weight Loss & Preserving Muscle
Kyle and Dr. Michael discuss nutrition, resistance training, weight-loss pace, and protecting muscle while using GLP-1 medications. - [09:09] Talking Honestly With Your Physician
The conversation turns to communication, treatment decisions, and why patients need to feel comfortable discussing what they are actually using. - [12:31] Emerging Compounds, Risk & Evidence
Kyle and Dr. Michael discuss sourcing, purity, risk tolerance, and why personal experiences should not replace good research. - [19:35] Nutrition & Training While Using GLP-1s
They cover protein, carbohydrates, workout nutrition, resistance training, and maintaining performance during weight loss. - [26:42] Hypertrophy, Rest Periods & Cardio
The discussion includes progressive overload, training to failure, rest periods, cardio, Hyrox, and physique goals. - [34:11] Women, Testosterone & Hormone Health
Kyle and Dr. Michael discuss testosterone, libido, energy, mood, sleep, and the broader hormone-health picture. - [37:09] Medical Terms That Are Harder to Say Than They Look
Kyle takes on a few medical terms and discovers that pronunciation can be a workout of its own. - [44:02] Rapid-Fire Q&A
The episode wraps with questions around peptides, blood pressure, stress, sauna, cold exposure, and recovery.
This content is for educational purposes only and is not a substitute for individualized medical advice.
