ABOUT THIS EPISODE
Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse anesthesia residents and CRNAs who want to feel more confident in complex pharmacology, physiology, and real-world anesthesia decision-making.
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In this episode:
- Exactly how PONV happens in the brain, no vague "vomiting center" hand waving
- All 5 real mechanisms behind how dexamethasone actually stops nausea and vomiting
- The practical dosing, timing, and combination strategy that gets the best PONV prevention
References:
- Chu CC, Hsing CH, Shieh JP, Chien CC, Ho CM, Wang JJ. The cellular mechanisms of the antiemetic action of dexamethasone and related glucocorticoids against vomiting. Eur J Pharmacol. 2014;722:48-54.
- Horn CC, Wallisch WJ, Homanics GE, Williams JP. Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting. Eur J Pharmacol. 2014;722:55-66.
- Ho CM, Wu HL, Ho ST, Wang JJ. Dexamethasone prevents postoperative nausea and vomiting: benefit versus risk. Acta Anaesthesiol Taiwan. 2011;49(3):100-104.
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- SEE/NCE Study Plan — a structured, week-by-week plan to pass your boards
- Non-Opioid Pharmacology Cheat Sheet — every non-opioid analgesic you need to know, one page
- GPCR Cheat Sheet — G-protein coupled receptors decoded for anesthesia
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