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O TYM ODCINKU
In this episode, we speak to Dr Colin Lindsay, Clinical Senior Lecturer at The Christie and The University of Manchester about the basic biology of lung cancer, focusing on:
- The high incidence of lung cancer here in Manchester
- The differences between non-small cell and small-cell lung cancer
- Oncogenic drivers in lung cancer such as the KRAS mutation
- His work on the drug sotorasib which targets KRAS mutant cancer and has now been approved by the FDA and for use in the UK by NICE
Colin Lindsay's research profile
EPAC-lung: European pooled analysis of the prognostic value of circulating tumour cells
KRAS: Reasons for optimism in lung cancer
On target: Rational approaches to KRAS inhibition for treatment of non-small cell lung carcinoma
Molecular characterization of primary and secondary resistance to RET inhibitors in patients
with advanced NSCLC and RET fusions (2022) https://www.ejcancer.com/article/S0959-8049(22)00871-1/fulltext
Język angielski
Zjednoczone Królestwo
WYSZUKAJ MINIONE ODCINKI
Wyszukaj minione odcinki One in Two.
INNE ODCINKI W TYM PODCASCIE
In this episode, we speak to Professor Caroline Dive, Professor of Cancer Pharmacology at The University of Manchester, Interim Director of the Cancer Research UK Manchester Institute and Director of the CRUK Cancer Biomarker Centre, about cancer biomarkers in lung cancer, focussing on:
Establis…
In this episode, we speak to Dr Emma Woodward and patient Nick Brown, about hereditary cancer predisposition, focusing on:
· Li Fraumeni Syndrome (LFS), a rare cancer predisposing condition which gives a 70% lifetime risk of developing cancer, caused by germline mutations in the TP53 gen…
In this episode, we speak to Corinne Faivre-Finn, a Professor of Thoracic Radiation Oncology about lung cancer clinical trials, focussing on:
· Radiotherapy: what it is and how it’s used to treat lung cancers
· Clinical trials: what are they, who are they for and how are they set up…
In this episode, we speak to Dr Fabio Gomes, a Consultant Medical Oncologist at The Christie NHS Foundation Trust, about lung cancer in never smokers, focusing on:
The commonality of lung cancer in never smokers
Why never smokers are susceptible to lung cancer, and why you only need lungs to ge…
Zastrzeżenie: Podcast i grafika osadzone na tej stronie pochodzą z The University of Manchester, który jest własnością jego właściciela i nie jest powiązany ani wspierany przez Listen Notes, Inc.
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