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In this Dementia Researcher Podcast episode, Dr Aitana Sogorb Esteve hosts a discussion with Dr Charlie Arber and Sam Crawford from University College London, discussing their work on familial British dementia (FBD)
FBD is a rare form of dementia affecting only a handful of families. The discussion explores the latest findings from human stem cell models that are helping researchers understand FBD’s unique genetic and pathological features, and how that can inform a wider understanding of familial Alzheimer’s Disease.
Topics covered include:
- Genetic causes and symptoms of familial British dementia
- Use of stem cell models, particularly induced pluripotent stem cells (iPSCs), to study FBD in the lab
- Potential biomarkers and implications for therapeutic research
- How funding from the Race Against Dementia Ignition Fund is supporting advancements in rare dementia research
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