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Send us Fan Mail Blood-brain barrier as a dynamic interface allowing selective passage of nutrients, peptides, and gut hormones. TOPICS DISCUSSED: Blood-Brain Barrier Structure: Capillary endothelial cells with tight junctions, absent fenestrae, and minimal vesicles create a selective interface; s…
Send us Fan Mail GHK-Copper and peptides in skin care, aging, and general health. TOPICS DISCUSSED: Endogenous Decline: GHK-copper levels peak in young adulthood then fall with age, reducing natural support for skin repair and collagen maintenance. Skin Penetration: Effective topical delivery depe…
Send us Fan Mail Ferroptosis, an iron-dependent cell death pathway driven by lipid peroxidation; chronoferoptosis, in which chronic stress sensitizes neurons gradually. TOPICS DISCUSSED: Cell Death Pathways: Apoptosis proceeds through regulated steps with surface “eat me” signals that enable non-i…
Send us Fan Mail Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism. TOPICS DISCUSSED: Mitochondrial Roles: Not just ATP production, but “speaker of the house” via communication molecules that “talk” to the rest of the cell. Origin of Communication: Mitochondri…
Send us Fan Mail Endogenous peptide diversity, GLP-1 drugs, and methods for novel peptide discovery. TOPICS DISCUSSED: Peptide Structure & Production: Short amino acid chains (3-50 residues) cleaved from larger precursors by PCSK enzymes, stored in dense-core vesicles, and released upon stimul…
Ansvarsfraskrivelse: Podkasten og kunstværket, det finnes indlejret på denne siden, er fra Nick Jikomes, som tilhører dens eier og ikke er tilknyttet eller godkjent av Listen Notes, Inc.