Pitstop: Beyond Binders: Evolving the Hyperphosphatemia Playbook

Hyperphosphatemia affects a significant proportion of patients receiving dialysis and remains a complex challenge for kidney care teams. In this episode of Kidney Commute Pit Stop, Anna Gaddy welcomes nephrologist Jessica Kendrick, clinical pharmacist Kimberly Holdener, and renal nutrition expert David St-Jules to explore what phosphorus management looks like in 2026.

The panel discusses the evolution of the "renal diet," emerging evidence on phosphorus bioavailability, the impact of food additives and processing, and how individualized nutrition counseling can improve patient outcomes. They also review traditional phosphorus binders, challenges with adherence and pill burden, and the emerging role of tenapanor, a first-in-class phosphorus blocker. Listeners will gain practical insights for helping patients navigate phosphorus management while maintaining a balanced, patient-centered approach to nutrition and quality of life.

This episode is supported by Ardelyx.

Please click here, to view a clinical bulletin update on managing hyperphosphatemia in patients on dialysis.

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