WEBVTT
1
00:00:00.090 --> 00:00:04.360
Well, prostate cancer, is there ever going to be a cure?
2
00:00:04.960 --> 00:00:08.640
With us today is Ed Randall, and Ed Randall is
3
00:00:08.679 --> 00:00:13.800
in charge of advocacy for finding the cure, and he'll
4
00:00:13.820 --> 00:00:17.000
tell us more about that. And then we have Dr.
5
00:00:17.089 --> 00:00:22.089
Daniel Petrilak, and I hope I said it right, and
6
00:00:22.109 --> 00:00:25.410
he's the professor of medicine and urology at the Yale
7
00:00:25.449 --> 00:00:30.289
School of Medicine. Well, let's start with Ed Randall. Ed Randall,
8
00:00:30.350 --> 00:00:33.250
you want to find a cure and you're putting people
9
00:00:33.289 --> 00:00:39.340
together to talk about it and pray about it. Do
10
00:00:39.799 --> 00:00:42.320
we need the Cardinal to come on his phone call
11
00:00:42.340 --> 00:00:43.740
with us to pray about it?
12
00:00:45.820 --> 00:00:49.880
That can't hurt, John, but before we begin our discussion,
13
00:00:50.200 --> 00:00:54.079
hats off to you, hats off to WABC for bringing
14
00:00:54.159 --> 00:00:59.289
attention to PSA screenings for prostate cancer, not just in
15
00:00:59.329 --> 00:01:04.049
September during Prostate Cancer Awareness Month, but year-round. We are
16
00:01:04.109 --> 00:01:07.879
so grateful, John, for your advocacy. We would love to
17
00:01:07.939 --> 00:01:11.099
have the Cardinals' power of prayer, but I will tell
18
00:01:11.140 --> 00:01:14.859
you that we are in business as a prostate cancer
19
00:01:14.900 --> 00:01:18.120
survivor to get men to go to the doctors to
20
00:01:18.239 --> 00:01:22.780
understand that early detection is everything, that there's a better
21
00:01:22.819 --> 00:01:26.549
than 90% cure rate if prostate cancer is detected early.
22
00:01:27.310 --> 00:01:29.390
Well, you know, we had a very bad situation at
23
00:01:29.569 --> 00:01:35.909
WABC where Sid Rosenberg's co-host never went to the doctor.
24
00:01:36.459 --> 00:01:39.379
never checked, and ended up with a stage four and
25
00:01:39.420 --> 00:01:42.010
he ended up passing away. And he would still be
26
00:01:42.049 --> 00:01:45.530
alive today if he went and was tested.
27
00:01:47.409 --> 00:01:51.739
That's exactly right. And I had a discussion with Bernie
28
00:01:51.760 --> 00:01:56.719
McGurk shortly before his passing, offering him the services of
29
00:01:56.760 --> 00:02:00.819
Fans for the Cure, where we have a medical advisory board, John,
30
00:02:01.180 --> 00:02:04.200
of dozens of the greatest urologists in this country, including
31
00:02:04.260 --> 00:02:06.260
the one that is on the phone with us right now.
32
00:02:07.519 --> 00:02:14.750
Tell us, Dr. Daniel Petrelak, Yale, you have a wonderful
33
00:02:14.810 --> 00:02:17.689
medical school up there. You saved the life of one
34
00:02:17.710 --> 00:02:21.710
of my best friends, Louis Cherivant, the former CEO of
35
00:02:22.319 --> 00:02:23.599
of United Technologies.
36
00:02:24.599 --> 00:02:28.939
Yes, I know him well. He's a great supporter of Yale,
37
00:02:28.979 --> 00:02:32.500
and we really appreciate him. Well, as Ed has said,
38
00:02:32.560 --> 00:02:36.400
early detection is one of the keys. More than 300,000
39
00:02:36.400 --> 00:02:38.680
men will be diagnosed with prostate cancer in the United
40
00:02:38.750 --> 00:02:42.310
States this year, and more than 36,000 men will die
41
00:02:42.330 --> 00:02:45.930
from metastatic disease. That's the second leading cause of cancer
42
00:02:45.949 --> 00:02:48.870
deaths in men. And, of course, what we'd like to
43
00:02:48.909 --> 00:02:53.659
do is detect disease early. But as you note from stats,
44
00:02:53.919 --> 00:03:00.000
there are some patients, unfortunately, who escape that particular early detection. Generally,
45
00:03:00.039 --> 00:03:03.419
a man who is 50 or higher should have a
46
00:03:03.500 --> 00:03:07.539
PSA performed. If you have family members who have prostate cancer,
47
00:03:07.939 --> 00:03:10.400
you should have your PSAs done earlier at 45. Also,
48
00:03:10.659 --> 00:03:13.740
if you're African-American, there's a higher rate of prostate cancer
49
00:03:13.780 --> 00:03:17.539
in African-Americans. So this is one of the things, detection
50
00:03:17.699 --> 00:03:21.509
of early disease. But If the unfortunate situation happens that
51
00:03:21.550 --> 00:03:24.469
the cancer is spread outside the prostate, we have many
52
00:03:24.530 --> 00:03:26.889
things that we can do to help. And in fact,
53
00:03:26.889 --> 00:03:30.189
22 years ago, I helped develop the first chemotherapy for
54
00:03:30.240 --> 00:03:34.219
prostate cancer, a drug called docetaxel, which helped to improve
55
00:03:34.280 --> 00:03:37.979
survival in men with the most advanced form of prostate cancer.
56
00:03:38.500 --> 00:03:41.960
Since that time, we've had multiple FDA approvals in this disease.
57
00:03:42.500 --> 00:03:44.400
And in fact, we're working on some new drugs at
58
00:03:44.439 --> 00:03:49.080
Yale right now that target what's called the androgen receptor,
59
00:03:49.099 --> 00:03:50.960
which is one of the targets we go after in
60
00:03:50.979 --> 00:03:53.810
prostate cancer in very, very novel ways. We have some
61
00:03:53.830 --> 00:03:56.270
drugs that have been developed at our institution that we're
62
00:03:56.289 --> 00:03:59.810
looking at in clinical trials and really, really excited about
63
00:03:59.830 --> 00:04:01.009
some of the results that we're seeing.
64
00:04:02.590 --> 00:04:03.129
Understood.
65
00:04:04.210 --> 00:04:08.849
And you think with prostate cancer, I think you can
66
00:04:08.930 --> 00:04:14.719
almost have a 100% cure rate if you catch it
67
00:04:14.750 --> 00:04:22.079
in time. What's the latest on early detection? You tell us.
68
00:04:23.500 --> 00:04:25.759
So if you detect the disease early, and there was
69
00:04:25.819 --> 00:04:30.180
always this controversy about whether PSA made a difference, really
70
00:04:30.199 --> 00:04:32.250
the important thing is you talk to your doctor if
71
00:04:32.290 --> 00:04:34.769
you do have the disease detected. Because there are really
72
00:04:34.829 --> 00:04:38.350
two forms of prostate cancer. There's one form that you
73
00:04:38.410 --> 00:04:42.790
die with, not from. It's not aggressive. The best way
74
00:04:42.829 --> 00:04:45.769
to describe it is Gleason 6, which is considered to
75
00:04:45.790 --> 00:04:48.730
be the least aggressive form of prostate cancer. That can
76
00:04:48.769 --> 00:04:52.610
be watched very, very successfully. But there's the other form
77
00:04:52.649 --> 00:04:55.730
as well that you can die from, which is where
78
00:04:55.750 --> 00:04:58.970
the 36,000 men a year fall into play. So if
79
00:04:59.009 --> 00:05:03.470
you can catch the disease early and treat it with
80
00:05:03.529 --> 00:05:07.620
either prostatectomy or radiation therapy, with or without hormone therapy,
81
00:05:08.050 --> 00:05:10.629
that potentially could also lead to a cure in these patients.
82
00:05:11.170 --> 00:05:13.629
So the important thing is talking to your doctor about
83
00:05:13.949 --> 00:05:15.129
what's appropriate for you.
84
00:05:17.089 --> 00:05:22.769
Understood. Anything else you want to tell us? Are you
85
00:05:25.170 --> 00:05:27.769
having any big get-togethers? Well, I'm in New York. In
86
00:05:27.829 --> 00:05:31.689
New York, to be able to talk about it publicly
87
00:05:32.009 --> 00:05:34.410
and to talk and move it publicly.
88
00:05:35.959 --> 00:05:38.759
Well, we have... Go ahead.
89
00:05:40.079 --> 00:05:42.980
I was going to say, John, that we're proud to
90
00:05:43.019 --> 00:05:45.779
tell you that last week in Yankee Stadium, fans for
91
00:05:45.800 --> 00:05:50.199
the Cure screened for free more than 200 men, 206
92
00:05:50.199 --> 00:05:52.810
to be exact, with a PSA exam. It was our
93
00:05:52.850 --> 00:05:59.389
14th annual event. free screening inside Yankee Stadium before and
94
00:05:59.430 --> 00:06:04.009
during their game, and we have screened now well over 2,000 men,
95
00:06:04.050 --> 00:06:09.540
and we're very proud of that. And just to add
96
00:06:09.600 --> 00:06:14.240
something that the doctor said, less than 50% of American men, John,
97
00:06:14.819 --> 00:06:20.410
know that a simple PSA exam is the initial diagnostic
98
00:06:20.529 --> 00:06:25.290
tool to detect prostate cancer. I was diagnosed at 47
99
00:06:25.290 --> 00:06:29.110
with a routine PSA blood test. So our job at
100
00:06:29.189 --> 00:06:35.009
Fans for the Cure is to increase that 50% exponentially
101
00:06:35.269 --> 00:06:38.160
so all men go to the doctors every year to
102
00:06:38.199 --> 00:06:42.060
get a simple PSA blood test that can potentially save
103
00:06:42.100 --> 00:06:42.540
their life.
104
00:06:43.620 --> 00:06:46.680
Thank you both for coming on this call today and
105
00:06:46.720 --> 00:06:50.959
making more people aware. Bernie McGurk made a zillion people
106
00:06:51.019 --> 00:06:56.269
aware of prostate cancer. And God, you know, we had 5,000
107
00:06:56.269 --> 00:06:59.600
people at St. Patrick's Day that day when we remembered him.
108
00:07:00.220 --> 00:07:02.959
And thank you all, guys, and we'll talk again real soon.
109
00:07:04.220 --> 00:07:04.620
Thank you.
110
00:07:04.740 --> 00:07:06.420
Thanks for the opportunity, John.
111
00:07:06.439 --> 00:07:08.180
And we're at fansforthecured.org.
1
00:00:00.090 --> 00:00:04.360
Well, prostate cancer, is there ever going to be a cure?
2
00:00:04.960 --> 00:00:08.640
With us today is Ed Randall, and Ed Randall is
3
00:00:08.679 --> 00:00:13.800
in charge of advocacy for finding the cure, and he'll
4
00:00:13.820 --> 00:00:17.000
tell us more about that. And then we have Dr.
5
00:00:17.089 --> 00:00:22.089
Daniel Petrilak, and I hope I said it right, and
6
00:00:22.109 --> 00:00:25.410
he's the professor of medicine and urology at the Yale
7
00:00:25.449 --> 00:00:30.289
School of Medicine. Well, let's start with Ed Randall. Ed Randall,
8
00:00:30.350 --> 00:00:33.250
you want to find a cure and you're putting people
9
00:00:33.289 --> 00:00:39.340
together to talk about it and pray about it. Do
10
00:00:39.799 --> 00:00:42.320
we need the Cardinal to come on his phone call
11
00:00:42.340 --> 00:00:43.740
with us to pray about it?
12
00:00:45.820 --> 00:00:49.880
That can't hurt, John, but before we begin our discussion,
13
00:00:50.200 --> 00:00:54.079
hats off to you, hats off to WABC for bringing
14
00:00:54.159 --> 00:00:59.289
attention to PSA screenings for prostate cancer, not just in
15
00:00:59.329 --> 00:01:04.049
September during Prostate Cancer Awareness Month, but year-round. We are
16
00:01:04.109 --> 00:01:07.879
so grateful, John, for your advocacy. We would love to
17
00:01:07.939 --> 00:01:11.099
have the Cardinals' power of prayer, but I will tell
18
00:01:11.140 --> 00:01:14.859
you that we are in business as a prostate cancer
19
00:01:14.900 --> 00:01:18.120
survivor to get men to go to the doctors to
20
00:01:18.239 --> 00:01:22.780
understand that early detection is everything, that there's a better
21
00:01:22.819 --> 00:01:26.549
than 90% cure rate if prostate cancer is detected early.
22
00:01:27.310 --> 00:01:29.390
Well, you know, we had a very bad situation at
23
00:01:29.569 --> 00:01:35.909
WABC where Sid Rosenberg's co-host never went to the doctor.
24
00:01:36.459 --> 00:01:39.379
never checked, and ended up with a stage four and
25
00:01:39.420 --> 00:01:42.010
he ended up passing away. And he would still be
26
00:01:42.049 --> 00:01:45.530
alive today if he went and was tested.
27
00:01:47.409 --> 00:01:51.739
That's exactly right. And I had a discussion with Bernie
28
00:01:51.760 --> 00:01:56.719
McGurk shortly before his passing, offering him the services of
29
00:01:56.760 --> 00:02:00.819
Fans for the Cure, where we have a medical advisory board, John,
30
00:02:01.180 --> 00:02:04.200
of dozens of the greatest urologists in this country, including
31
00:02:04.260 --> 00:02:06.260
the one that is on the phone with us right now.
32
00:02:07.519 --> 00:02:14.750
Tell us, Dr. Daniel Petrelak, Yale, you have a wonderful
33
00:02:14.810 --> 00:02:17.689
medical school up there. You saved the life of one
34
00:02:17.710 --> 00:02:21.710
of my best friends, Louis Cherivant, the former CEO of
35
00:02:22.319 --> 00:02:23.599
of United Technologies.
36
00:02:24.599 --> 00:02:28.939
Yes, I know him well. He's a great supporter of Yale,
37
00:02:28.979 --> 00:02:32.500
and we really appreciate him. Well, as Ed has said,
38
00:02:32.560 --> 00:02:36.400
early detection is one of the keys. More than 300,000
39
00:02:36.400 --> 00:02:38.680
men will be diagnosed with prostate cancer in the United
40
00:02:38.750 --> 00:02:42.310
States this year, and more than 36,000 men will die
41
00:02:42.330 --> 00:02:45.930
from metastatic disease. That's the second leading cause of cancer
42
00:02:45.949 --> 00:02:48.870
deaths in men. And, of course, what we'd like to
43
00:02:48.909 --> 00:02:53.659
do is detect disease early. But as you note from stats,
44
00:02:53.919 --> 00:03:00.000
there are some patients, unfortunately, who escape that particular early detection. Generally,
45
00:03:00.039 --> 00:03:03.419
a man who is 50 or higher should have a
46
00:03:03.500 --> 00:03:07.539
PSA performed. If you have family members who have prostate cancer,
47
00:03:07.939 --> 00:03:10.400
you should have your PSAs done earlier at 45. Also,
48
00:03:10.659 --> 00:03:13.740
if you're African-American, there's a higher rate of prostate cancer
49
00:03:13.780 --> 00:03:17.539
in African-Americans. So this is one of the things, detection
50
00:03:17.699 --> 00:03:21.509
of early disease. But If the unfortunate situation happens that
51
00:03:21.550 --> 00:03:24.469
the cancer is spread outside the prostate, we have many
52
00:03:24.530 --> 00:03:26.889
things that we can do to help. And in fact,
53
00:03:26.889 --> 00:03:30.189
22 years ago, I helped develop the first chemotherapy for
54
00:03:30.240 --> 00:03:34.219
prostate cancer, a drug called docetaxel, which helped to improve
55
00:03:34.280 --> 00:03:37.979
survival in men with the most advanced form of prostate cancer.
56
00:03:38.500 --> 00:03:41.960
Since that time, we've had multiple FDA approvals in this disease.
57
00:03:42.500 --> 00:03:44.400
And in fact, we're working on some new drugs at
58
00:03:44.439 --> 00:03:49.080
Yale right now that target what's called the androgen receptor,
59
00:03:49.099 --> 00:03:50.960
which is one of the targets we go after in
60
00:03:50.979 --> 00:03:53.810
prostate cancer in very, very novel ways. We have some
61
00:03:53.830 --> 00:03:56.270
drugs that have been developed at our institution that we're
62
00:03:56.289 --> 00:03:59.810
looking at in clinical trials and really, really excited about
63
00:03:59.830 --> 00:04:01.009
some of the results that we're seeing.
64
00:04:02.590 --> 00:04:03.129
Understood.
65
00:04:04.210 --> 00:04:08.849
And you think with prostate cancer, I think you can
66
00:04:08.930 --> 00:04:14.719
almost have a 100% cure rate if you catch it
67
00:04:14.750 --> 00:04:22.079
in time. What's the latest on early detection? You tell us.
68
00:04:23.500 --> 00:04:25.759
So if you detect the disease early, and there was
69
00:04:25.819 --> 00:04:30.180
always this controversy about whether PSA made a difference, really
70
00:04:30.199 --> 00:04:32.250
the important thing is you talk to your doctor if
71
00:04:32.290 --> 00:04:34.769
you do have the disease detected. Because there are really
72
00:04:34.829 --> 00:04:38.350
two forms of prostate cancer. There's one form that you
73
00:04:38.410 --> 00:04:42.790
die with, not from. It's not aggressive. The best way
74
00:04:42.829 --> 00:04:45.769
to describe it is Gleason 6, which is considered to
75
00:04:45.790 --> 00:04:48.730
be the least aggressive form of prostate cancer. That can
76
00:04:48.769 --> 00:04:52.610
be watched very, very successfully. But there's the other form
77
00:04:52.649 --> 00:04:55.730
as well that you can die from, which is where
78
00:04:55.750 --> 00:04:58.970
the 36,000 men a year fall into play. So if
79
00:04:59.009 --> 00:05:03.470
you can catch the disease early and treat it with
80
00:05:03.529 --> 00:05:07.620
either prostatectomy or radiation therapy, with or without hormone therapy,
81
00:05:08.050 --> 00:05:10.629
that potentially could also lead to a cure in these patients.
82
00:05:11.170 --> 00:05:13.629
So the important thing is talking to your doctor about
83
00:05:13.949 --> 00:05:15.129
what's appropriate for you.
84
00:05:17.089 --> 00:05:22.769
Understood. Anything else you want to tell us? Are you
85
00:05:25.170 --> 00:05:27.769
having any big get-togethers? Well, I'm in New York. In
86
00:05:27.829 --> 00:05:31.689
New York, to be able to talk about it publicly
87
00:05:32.009 --> 00:05:34.410
and to talk and move it publicly.
88
00:05:35.959 --> 00:05:38.759
Well, we have... Go ahead.
89
00:05:40.079 --> 00:05:42.980
I was going to say, John, that we're proud to
90
00:05:43.019 --> 00:05:45.779
tell you that last week in Yankee Stadium, fans for
91
00:05:45.800 --> 00:05:50.199
the Cure screened for free more than 200 men, 206
92
00:05:50.199 --> 00:05:52.810
to be exact, with a PSA exam. It was our
93
00:05:52.850 --> 00:05:59.389
14th annual event. free screening inside Yankee Stadium before and
94
00:05:59.430 --> 00:06:04.009
during their game, and we have screened now well over 2,000 men,
95
00:06:04.050 --> 00:06:09.540
and we're very proud of that. And just to add
96
00:06:09.600 --> 00:06:14.240
something that the doctor said, less than 50% of American men, John,
97
00:06:14.819 --> 00:06:20.410
know that a simple PSA exam is the initial diagnostic
98
00:06:20.529 --> 00:06:25.290
tool to detect prostate cancer. I was diagnosed at 47
99
00:06:25.290 --> 00:06:29.110
with a routine PSA blood test. So our job at
100
00:06:29.189 --> 00:06:35.009
Fans for the Cure is to increase that 50% exponentially
101
00:06:35.269 --> 00:06:38.160
so all men go to the doctors every year to
102
00:06:38.199 --> 00:06:42.060
get a simple PSA blood test that can potentially save
103
00:06:42.100 --> 00:06:42.540
their life.
104
00:06:43.620 --> 00:06:46.680
Thank you both for coming on this call today and
105
00:06:46.720 --> 00:06:50.959
making more people aware. Bernie McGurk made a zillion people
106
00:06:51.019 --> 00:06:56.269
aware of prostate cancer. And God, you know, we had 5,000
107
00:06:56.269 --> 00:06:59.600
people at St. Patrick's Day that day when we remembered him.
108
00:07:00.220 --> 00:07:02.959
And thank you all, guys, and we'll talk again real soon.
109
00:07:04.220 --> 00:07:04.620
Thank you.
110
00:07:04.740 --> 00:07:06.420
Thanks for the opportunity, John.
111
00:07:06.439 --> 00:07:08.180
And we're at fansforthecured.org.
