WEBVTT
Kind: captions
Language: en
00:00:04.560 --> 00:00:06.590
Mhm.
00:00:06.600 --> 00:00:07.710
All right, from here your family. I've
00:00:07.720 --> 00:00:09.230
got a hot one for you today. I want to
00:00:09.240 --> 00:00:11.510
talk about GHK copper. GHK copper is one
00:00:11.520 --> 00:00:13.110
of those very interesting compounds that
00:00:13.120 --> 00:00:14.830
actually has a lot of human research,
00:00:14.840 --> 00:00:16.470
which is a very important factor in a
00:00:16.480 --> 00:00:18.670
world with so much preclinical data and
00:00:18.680 --> 00:00:20.350
animal model research. We actually have
00:00:20.360 --> 00:00:22.310
something here with a ton of human data.
00:00:22.320 --> 00:00:23.710
This is a structure that's been studied
00:00:23.720 --> 00:00:24.790
or excuse me, a compound that's been
00:00:24.800 --> 00:00:27.230
studied since the early 1970s. Most of
00:00:27.240 --> 00:00:29.150
the human data does exist with topical
00:00:29.160 --> 00:00:30.950
application, but there are broad
00:00:30.960 --> 00:00:32.830
systems-based applications that can be
00:00:32.840 --> 00:00:34.670
inferred from this with preclinical data
00:00:34.680 --> 00:00:36.950
in addition to a very nice safety
00:00:36.960 --> 00:00:39.030
profile. GHK copper becomes a very
00:00:39.040 --> 00:00:40.830
important structure for repair and
00:00:40.840 --> 00:00:42.550
recovery, and here's why. Think of it
00:00:42.560 --> 00:00:45.070
like a systems-level regulator. So, we
00:00:45.080 --> 00:00:46.790
talk often about how important
00:00:46.800 --> 00:00:48.990
environment is in our ability to
00:00:49.000 --> 00:00:51.310
recover, repair, and have just
00:00:51.320 --> 00:00:53.230
ultimately good cellular function. That
00:00:53.240 --> 00:00:54.910
environment is so important because you
00:00:54.920 --> 00:00:57.030
can put a very good tool in a poor
00:00:57.040 --> 00:00:58.950
environment and it can either not work
00:00:58.960 --> 00:01:01.230
or it can amplify dysfunction. So, let's
00:01:01.240 --> 00:01:04.110
talk about GHK copper itself. So, GHK,
00:01:04.120 --> 00:01:07.030
that first part is glycyl, histidyl, and
00:01:07.040 --> 00:01:09.030
lysyl bound to a copper. Now,
00:01:09.040 --> 00:01:11.310
ultimately, copper is a very potent
00:01:11.320 --> 00:01:13.310
mechanism. If attaching to the incorrect
00:01:13.320 --> 00:01:15.150
tissues at the inappropriate time, it is
00:01:15.160 --> 00:01:18.270
a major redox disrupter. However, this
00:01:18.280 --> 00:01:20.270
glycyl, histidyl, and lysyl creates a
00:01:20.280 --> 00:01:22.830
square planar geometry around copper
00:01:22.840 --> 00:01:24.830
protecting our tissues until just the
00:01:24.840 --> 00:01:26.670
right time. When it goes in, this is the
00:01:26.680 --> 00:01:28.910
cool part. It's a gene modulator. It has
00:01:28.920 --> 00:01:31.230
been proven to uh affect and modulate
00:01:31.240 --> 00:01:34.350
4,000 plus genes in the human. Now, that
00:01:34.360 --> 00:01:35.830
might sound scary at first, but the
00:01:35.840 --> 00:01:37.910
reality is what we found is the majority
00:01:37.920 --> 00:01:39.710
of these are just favorable. They've not
00:01:39.720 --> 00:01:41.670
found any deleterious movements as a
00:01:41.680 --> 00:01:43.270
result of these gene expressions. That
00:01:43.280 --> 00:01:44.990
distribution breaks down into some
00:01:45.000 --> 00:01:46.750
upregulation and some downregulation.
00:01:46.760 --> 00:01:48.910
Approximately 30% of the gene
00:01:48.920 --> 00:01:50.590
transcription expressions are
00:01:50.600 --> 00:01:53.230
upregulation of appropriate factors
00:01:53.240 --> 00:01:54.750
promoting healing and recovery and
00:01:54.760 --> 00:01:56.030
repair. The remaining are
00:01:56.040 --> 00:01:57.710
downregulating. So, let's talk about
00:01:57.720 --> 00:01:59.550
some of those factors, some direct
00:01:59.560 --> 00:02:02.030
actions of GHK copper. One is very
00:02:02.040 --> 00:02:04.270
important from an inflammation reduction
00:02:04.280 --> 00:02:06.070
agent is direct suppression of
00:02:06.080 --> 00:02:08.950
NF-kappaB. NF-kappaB is known to be a
00:02:08.960 --> 00:02:11.030
major contributor to pro-inflammatory
00:02:11.040 --> 00:02:14.270
states. NF-kappaB goes into the nuclear
00:02:14.280 --> 00:02:16.910
center, creates cyto- cytokine release.
00:02:16.920 --> 00:02:19.110
So, things like IL-1 beta, tumor
00:02:19.120 --> 00:02:22.070
necrosis factor alpha, IL-6, these other
00:02:22.080 --> 00:02:22.990
factors that are known to be
00:02:23.000 --> 00:02:25.110
pro-inflammatory and create inflammation
00:02:25.120 --> 00:02:26.190
throughout the body. Now, they're not
00:02:26.200 --> 00:02:28.110
always bad, but if inappropriate
00:02:28.120 --> 00:02:30.790
inappropriate state, they can be uh
00:02:30.800 --> 00:02:32.630
negative as a result of excessive
00:02:32.640 --> 00:02:34.750
expression. So, GHK copper goes in to
00:02:34.760 --> 00:02:36.910
suppress that NF-kappaB expression of
00:02:36.920 --> 00:02:38.790
cytokine release. In addition to that,
00:02:38.800 --> 00:02:40.190
so the other side, the protective
00:02:40.200 --> 00:02:41.830
mechanisms. It activates something
00:02:41.840 --> 00:02:44.230
called NRF2, which is the master
00:02:44.240 --> 00:02:46.870
regulator for the antioxidant response
00:02:46.880 --> 00:02:48.910
elements. So, these are things like
00:02:48.920 --> 00:02:51.390
superoxide dismutase, catalase, and then
00:02:51.400 --> 00:02:53.070
one of my favorites, glutathione
00:02:53.080 --> 00:02:54.390
peroxidase. So, these are the things
00:02:54.400 --> 00:02:55.710
that are going out and helping to
00:02:55.720 --> 00:02:58.030
protect you from things like reactive
00:02:58.040 --> 00:03:00.830
oxygen species, free radicals. These bad
00:03:00.840 --> 00:03:02.550
agents that can float in excess
00:03:02.560 --> 00:03:03.910
throughout the body. They're not always
00:03:03.920 --> 00:03:05.670
bad, but if they're left unfettered, if
00:03:05.680 --> 00:03:08.110
they're left to go unregulated, they can
00:03:08.120 --> 00:03:09.790
be very problematic. In addition to
00:03:09.800 --> 00:03:12.070
that, we know that there are direct
00:03:12.080 --> 00:03:14.310
repair mechanisms that GHK copper
00:03:14.320 --> 00:03:16.229
effects that are very unique. Things
00:03:16.239 --> 00:03:18.509
like nerve growth factor, neurotrophin
00:03:18.519 --> 00:03:20.630
3, neurotrophin 4. These have been
00:03:20.640 --> 00:03:23.190
studied in peripheral neuropathy models
00:03:23.200 --> 00:03:25.670
as well as in other nerve injury states.
00:03:25.680 --> 00:03:27.710
And it's a phenomenal uh agent as a
00:03:27.720 --> 00:03:29.390
result of that. In addition to that, so
00:03:29.400 --> 00:03:30.750
and this is something that is seen very
00:03:30.760 --> 00:03:32.670
commonly in skin or just in other
00:03:32.680 --> 00:03:34.870
tissues is its ability to modulate
00:03:34.880 --> 00:03:37.030
transforming growth factor beta. Now,
00:03:37.040 --> 00:03:38.790
transforming growth factor beta is very
00:03:38.800 --> 00:03:40.630
important in the recovery process, but
00:03:40.640 --> 00:03:42.990
it can get skewed as a result of
00:03:43.000 --> 00:03:44.670
stabilization of something called metal
00:03:44.680 --> 00:03:47.030
metalloproteinases, we get improved
00:03:47.040 --> 00:03:49.150
deposition of certain types of collagen.
00:03:49.160 --> 00:03:51.150
So, not only just type 1 collagen, which
00:03:51.160 --> 00:03:52.790
tends to be more fibrotic. We get
00:03:52.800 --> 00:03:54.950
appropriate distributions of collagen
00:03:54.960 --> 00:03:57.110
one, collagen three, and there's other
00:03:57.120 --> 00:03:58.910
stabilization mechanisms, which leads
00:03:58.920 --> 00:04:01.430
ultimately to more compliant tissues,
00:04:01.440 --> 00:04:03.350
more bounded tissues, tissues that are
00:04:03.360 --> 00:04:04.430
healthier, that have a better
00:04:04.440 --> 00:04:06.390
extracellular matrix. So, you we've set
00:04:06.400 --> 00:04:08.750
the environment for better healing and
00:04:08.760 --> 00:04:10.670
better recovery of tissues that are more
00:04:10.680 --> 00:04:12.949
durable and more resilient ultimately.
00:04:12.959 --> 00:04:14.270
One of the last things I do want to talk
00:04:14.280 --> 00:04:16.150
about because we get it often is to talk
00:04:16.160 --> 00:04:19.030
about its utility in hair loss. Research
00:04:19.040 --> 00:04:20.390
is mixed with this, meaning that the
00:04:20.400 --> 00:04:22.110
outcomes are mixed. I think if you pick
00:04:22.120 --> 00:04:24.670
the appropriate person, GHK-Cu can be an
00:04:24.680 --> 00:04:26.550
effective hair loss agent. If you look
00:04:26.560 --> 00:04:29.270
at how it works, it helps to stabilize
00:04:29.280 --> 00:04:30.670
something called hepatocyte growth
00:04:30.680 --> 00:04:32.830
factor in the follicular cells. So, in a
00:04:32.840 --> 00:04:35.350
person who has alopecia, who has
00:04:35.360 --> 00:04:37.750
TGF-β1-mediated
00:04:37.760 --> 00:04:40.110
follicle miniaturization, you're going
00:04:40.120 --> 00:04:41.830
to get stabilization of that. In
00:04:41.840 --> 00:04:44.230
addition to, it extends the anagen or
00:04:44.240 --> 00:04:46.190
the growth phase factor of the hair
00:04:46.200 --> 00:04:48.390
follicle. So, you can get more durable
00:04:48.400 --> 00:04:50.270
hair follicles. You can get some
00:04:50.280 --> 00:04:52.150
recovery of the hair follicles as well.
00:04:52.160 --> 00:04:53.590
I wouldn't say that it's robust, but it
00:04:53.600 --> 00:04:55.470
does have an application there that
00:04:55.480 --> 00:04:58.150
people do get some regular benefit over
00:04:58.160 --> 00:05:00.030
time. Remember, most of these things,
00:05:00.040 --> 00:05:01.950
this is the marathon and not a sprint.
00:05:01.960 --> 00:05:03.230
This is something that has to be used
00:05:03.240 --> 00:05:05.230
appropriately, and the system has to be
00:05:05.240 --> 00:05:07.030
good. In addition to that, there is that
00:05:07.040 --> 00:05:08.909
anti-inflammatory benefit to the scalp
00:05:08.919 --> 00:05:10.950
in reducing inflammation at the scalp,
00:05:10.960 --> 00:05:12.830
promoting blood flow can be a very
00:05:12.840 --> 00:05:14.030
favorable thing for those hair
00:05:14.040 --> 00:05:15.790
follicles. So, hopefully, after this
00:05:15.800 --> 00:05:17.909
brief overview of how how this agent
00:05:17.919 --> 00:05:19.470
actually works in the body, you can see
00:05:19.480 --> 00:05:21.670
why it's so sought after and why it's
00:05:21.680 --> 00:05:23.670
ultimately so effective if put into the
00:05:23.680 --> 00:05:25.710
right system and ultimately when it's
00:05:25.720 --> 00:05:28.150
used to create favorable changes in a
00:05:28.160 --> 00:05:29.710
system, you're going to see that other
00:05:29.720 --> 00:05:31.550
agents that are used, other peptides,
00:05:31.560 --> 00:05:33.390
other supplements, other lifestyle
00:05:33.400 --> 00:05:35.550
factors are going to be enhanced because
00:05:35.560 --> 00:05:37.070
you've changed that environment. So, I
00:05:37.080 --> 00:05:38.310
hope that this is helpful. You
00:05:38.320 --> 00:05:39.470
definitely want to use these agents
00:05:39.480 --> 00:05:41.510
appropriately. This is preclinical data,
00:05:41.520 --> 00:05:42.790
and this is not something that has been
00:05:42.800 --> 00:05:44.750
done in large patient cohorts. So, we
00:05:44.760 --> 00:05:46.190
have to be very appropriate when we're
00:05:46.200 --> 00:05:47.670
choosing these agents, but they can be
00:05:47.680 --> 00:05:54.110
very impactful. All right, take care.
00:05:54.120 --> 00:05:56.320
Mhm.
Kind: captions
Language: en
00:00:04.560 --> 00:00:06.590
Mhm.
00:00:06.600 --> 00:00:07.710
All right, from here your family. I've
00:00:07.720 --> 00:00:09.230
got a hot one for you today. I want to
00:00:09.240 --> 00:00:11.510
talk about GHK copper. GHK copper is one
00:00:11.520 --> 00:00:13.110
of those very interesting compounds that
00:00:13.120 --> 00:00:14.830
actually has a lot of human research,
00:00:14.840 --> 00:00:16.470
which is a very important factor in a
00:00:16.480 --> 00:00:18.670
world with so much preclinical data and
00:00:18.680 --> 00:00:20.350
animal model research. We actually have
00:00:20.360 --> 00:00:22.310
something here with a ton of human data.
00:00:22.320 --> 00:00:23.710
This is a structure that's been studied
00:00:23.720 --> 00:00:24.790
or excuse me, a compound that's been
00:00:24.800 --> 00:00:27.230
studied since the early 1970s. Most of
00:00:27.240 --> 00:00:29.150
the human data does exist with topical
00:00:29.160 --> 00:00:30.950
application, but there are broad
00:00:30.960 --> 00:00:32.830
systems-based applications that can be
00:00:32.840 --> 00:00:34.670
inferred from this with preclinical data
00:00:34.680 --> 00:00:36.950
in addition to a very nice safety
00:00:36.960 --> 00:00:39.030
profile. GHK copper becomes a very
00:00:39.040 --> 00:00:40.830
important structure for repair and
00:00:40.840 --> 00:00:42.550
recovery, and here's why. Think of it
00:00:42.560 --> 00:00:45.070
like a systems-level regulator. So, we
00:00:45.080 --> 00:00:46.790
talk often about how important
00:00:46.800 --> 00:00:48.990
environment is in our ability to
00:00:49.000 --> 00:00:51.310
recover, repair, and have just
00:00:51.320 --> 00:00:53.230
ultimately good cellular function. That
00:00:53.240 --> 00:00:54.910
environment is so important because you
00:00:54.920 --> 00:00:57.030
can put a very good tool in a poor
00:00:57.040 --> 00:00:58.950
environment and it can either not work
00:00:58.960 --> 00:01:01.230
or it can amplify dysfunction. So, let's
00:01:01.240 --> 00:01:04.110
talk about GHK copper itself. So, GHK,
00:01:04.120 --> 00:01:07.030
that first part is glycyl, histidyl, and
00:01:07.040 --> 00:01:09.030
lysyl bound to a copper. Now,
00:01:09.040 --> 00:01:11.310
ultimately, copper is a very potent
00:01:11.320 --> 00:01:13.310
mechanism. If attaching to the incorrect
00:01:13.320 --> 00:01:15.150
tissues at the inappropriate time, it is
00:01:15.160 --> 00:01:18.270
a major redox disrupter. However, this
00:01:18.280 --> 00:01:20.270
glycyl, histidyl, and lysyl creates a
00:01:20.280 --> 00:01:22.830
square planar geometry around copper
00:01:22.840 --> 00:01:24.830
protecting our tissues until just the
00:01:24.840 --> 00:01:26.670
right time. When it goes in, this is the
00:01:26.680 --> 00:01:28.910
cool part. It's a gene modulator. It has
00:01:28.920 --> 00:01:31.230
been proven to uh affect and modulate
00:01:31.240 --> 00:01:34.350
4,000 plus genes in the human. Now, that
00:01:34.360 --> 00:01:35.830
might sound scary at first, but the
00:01:35.840 --> 00:01:37.910
reality is what we found is the majority
00:01:37.920 --> 00:01:39.710
of these are just favorable. They've not
00:01:39.720 --> 00:01:41.670
found any deleterious movements as a
00:01:41.680 --> 00:01:43.270
result of these gene expressions. That
00:01:43.280 --> 00:01:44.990
distribution breaks down into some
00:01:45.000 --> 00:01:46.750
upregulation and some downregulation.
00:01:46.760 --> 00:01:48.910
Approximately 30% of the gene
00:01:48.920 --> 00:01:50.590
transcription expressions are
00:01:50.600 --> 00:01:53.230
upregulation of appropriate factors
00:01:53.240 --> 00:01:54.750
promoting healing and recovery and
00:01:54.760 --> 00:01:56.030
repair. The remaining are
00:01:56.040 --> 00:01:57.710
downregulating. So, let's talk about
00:01:57.720 --> 00:01:59.550
some of those factors, some direct
00:01:59.560 --> 00:02:02.030
actions of GHK copper. One is very
00:02:02.040 --> 00:02:04.270
important from an inflammation reduction
00:02:04.280 --> 00:02:06.070
agent is direct suppression of
00:02:06.080 --> 00:02:08.950
NF-kappaB. NF-kappaB is known to be a
00:02:08.960 --> 00:02:11.030
major contributor to pro-inflammatory
00:02:11.040 --> 00:02:14.270
states. NF-kappaB goes into the nuclear
00:02:14.280 --> 00:02:16.910
center, creates cyto- cytokine release.
00:02:16.920 --> 00:02:19.110
So, things like IL-1 beta, tumor
00:02:19.120 --> 00:02:22.070
necrosis factor alpha, IL-6, these other
00:02:22.080 --> 00:02:22.990
factors that are known to be
00:02:23.000 --> 00:02:25.110
pro-inflammatory and create inflammation
00:02:25.120 --> 00:02:26.190
throughout the body. Now, they're not
00:02:26.200 --> 00:02:28.110
always bad, but if inappropriate
00:02:28.120 --> 00:02:30.790
inappropriate state, they can be uh
00:02:30.800 --> 00:02:32.630
negative as a result of excessive
00:02:32.640 --> 00:02:34.750
expression. So, GHK copper goes in to
00:02:34.760 --> 00:02:36.910
suppress that NF-kappaB expression of
00:02:36.920 --> 00:02:38.790
cytokine release. In addition to that,
00:02:38.800 --> 00:02:40.190
so the other side, the protective
00:02:40.200 --> 00:02:41.830
mechanisms. It activates something
00:02:41.840 --> 00:02:44.230
called NRF2, which is the master
00:02:44.240 --> 00:02:46.870
regulator for the antioxidant response
00:02:46.880 --> 00:02:48.910
elements. So, these are things like
00:02:48.920 --> 00:02:51.390
superoxide dismutase, catalase, and then
00:02:51.400 --> 00:02:53.070
one of my favorites, glutathione
00:02:53.080 --> 00:02:54.390
peroxidase. So, these are the things
00:02:54.400 --> 00:02:55.710
that are going out and helping to
00:02:55.720 --> 00:02:58.030
protect you from things like reactive
00:02:58.040 --> 00:03:00.830
oxygen species, free radicals. These bad
00:03:00.840 --> 00:03:02.550
agents that can float in excess
00:03:02.560 --> 00:03:03.910
throughout the body. They're not always
00:03:03.920 --> 00:03:05.670
bad, but if they're left unfettered, if
00:03:05.680 --> 00:03:08.110
they're left to go unregulated, they can
00:03:08.120 --> 00:03:09.790
be very problematic. In addition to
00:03:09.800 --> 00:03:12.070
that, we know that there are direct
00:03:12.080 --> 00:03:14.310
repair mechanisms that GHK copper
00:03:14.320 --> 00:03:16.229
effects that are very unique. Things
00:03:16.239 --> 00:03:18.509
like nerve growth factor, neurotrophin
00:03:18.519 --> 00:03:20.630
3, neurotrophin 4. These have been
00:03:20.640 --> 00:03:23.190
studied in peripheral neuropathy models
00:03:23.200 --> 00:03:25.670
as well as in other nerve injury states.
00:03:25.680 --> 00:03:27.710
And it's a phenomenal uh agent as a
00:03:27.720 --> 00:03:29.390
result of that. In addition to that, so
00:03:29.400 --> 00:03:30.750
and this is something that is seen very
00:03:30.760 --> 00:03:32.670
commonly in skin or just in other
00:03:32.680 --> 00:03:34.870
tissues is its ability to modulate
00:03:34.880 --> 00:03:37.030
transforming growth factor beta. Now,
00:03:37.040 --> 00:03:38.790
transforming growth factor beta is very
00:03:38.800 --> 00:03:40.630
important in the recovery process, but
00:03:40.640 --> 00:03:42.990
it can get skewed as a result of
00:03:43.000 --> 00:03:44.670
stabilization of something called metal
00:03:44.680 --> 00:03:47.030
metalloproteinases, we get improved
00:03:47.040 --> 00:03:49.150
deposition of certain types of collagen.
00:03:49.160 --> 00:03:51.150
So, not only just type 1 collagen, which
00:03:51.160 --> 00:03:52.790
tends to be more fibrotic. We get
00:03:52.800 --> 00:03:54.950
appropriate distributions of collagen
00:03:54.960 --> 00:03:57.110
one, collagen three, and there's other
00:03:57.120 --> 00:03:58.910
stabilization mechanisms, which leads
00:03:58.920 --> 00:04:01.430
ultimately to more compliant tissues,
00:04:01.440 --> 00:04:03.350
more bounded tissues, tissues that are
00:04:03.360 --> 00:04:04.430
healthier, that have a better
00:04:04.440 --> 00:04:06.390
extracellular matrix. So, you we've set
00:04:06.400 --> 00:04:08.750
the environment for better healing and
00:04:08.760 --> 00:04:10.670
better recovery of tissues that are more
00:04:10.680 --> 00:04:12.949
durable and more resilient ultimately.
00:04:12.959 --> 00:04:14.270
One of the last things I do want to talk
00:04:14.280 --> 00:04:16.150
about because we get it often is to talk
00:04:16.160 --> 00:04:19.030
about its utility in hair loss. Research
00:04:19.040 --> 00:04:20.390
is mixed with this, meaning that the
00:04:20.400 --> 00:04:22.110
outcomes are mixed. I think if you pick
00:04:22.120 --> 00:04:24.670
the appropriate person, GHK-Cu can be an
00:04:24.680 --> 00:04:26.550
effective hair loss agent. If you look
00:04:26.560 --> 00:04:29.270
at how it works, it helps to stabilize
00:04:29.280 --> 00:04:30.670
something called hepatocyte growth
00:04:30.680 --> 00:04:32.830
factor in the follicular cells. So, in a
00:04:32.840 --> 00:04:35.350
person who has alopecia, who has
00:04:35.360 --> 00:04:37.750
TGF-β1-mediated
00:04:37.760 --> 00:04:40.110
follicle miniaturization, you're going
00:04:40.120 --> 00:04:41.830
to get stabilization of that. In
00:04:41.840 --> 00:04:44.230
addition to, it extends the anagen or
00:04:44.240 --> 00:04:46.190
the growth phase factor of the hair
00:04:46.200 --> 00:04:48.390
follicle. So, you can get more durable
00:04:48.400 --> 00:04:50.270
hair follicles. You can get some
00:04:50.280 --> 00:04:52.150
recovery of the hair follicles as well.
00:04:52.160 --> 00:04:53.590
I wouldn't say that it's robust, but it
00:04:53.600 --> 00:04:55.470
does have an application there that
00:04:55.480 --> 00:04:58.150
people do get some regular benefit over
00:04:58.160 --> 00:05:00.030
time. Remember, most of these things,
00:05:00.040 --> 00:05:01.950
this is the marathon and not a sprint.
00:05:01.960 --> 00:05:03.230
This is something that has to be used
00:05:03.240 --> 00:05:05.230
appropriately, and the system has to be
00:05:05.240 --> 00:05:07.030
good. In addition to that, there is that
00:05:07.040 --> 00:05:08.909
anti-inflammatory benefit to the scalp
00:05:08.919 --> 00:05:10.950
in reducing inflammation at the scalp,
00:05:10.960 --> 00:05:12.830
promoting blood flow can be a very
00:05:12.840 --> 00:05:14.030
favorable thing for those hair
00:05:14.040 --> 00:05:15.790
follicles. So, hopefully, after this
00:05:15.800 --> 00:05:17.909
brief overview of how how this agent
00:05:17.919 --> 00:05:19.470
actually works in the body, you can see
00:05:19.480 --> 00:05:21.670
why it's so sought after and why it's
00:05:21.680 --> 00:05:23.670
ultimately so effective if put into the
00:05:23.680 --> 00:05:25.710
right system and ultimately when it's
00:05:25.720 --> 00:05:28.150
used to create favorable changes in a
00:05:28.160 --> 00:05:29.710
system, you're going to see that other
00:05:29.720 --> 00:05:31.550
agents that are used, other peptides,
00:05:31.560 --> 00:05:33.390
other supplements, other lifestyle
00:05:33.400 --> 00:05:35.550
factors are going to be enhanced because
00:05:35.560 --> 00:05:37.070
you've changed that environment. So, I
00:05:37.080 --> 00:05:38.310
hope that this is helpful. You
00:05:38.320 --> 00:05:39.470
definitely want to use these agents
00:05:39.480 --> 00:05:41.510
appropriately. This is preclinical data,
00:05:41.520 --> 00:05:42.790
and this is not something that has been
00:05:42.800 --> 00:05:44.750
done in large patient cohorts. So, we
00:05:44.760 --> 00:05:46.190
have to be very appropriate when we're
00:05:46.200 --> 00:05:47.670
choosing these agents, but they can be
00:05:47.680 --> 00:05:54.110
very impactful. All right, take care.
00:05:54.120 --> 00:05:56.320
Mhm.
