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Parkinson's disease (PD) affects more than a million people in the US. Jeanne Loring, professor and the founding director of the Center for Regenerative Medicine at The Scripps Research Institute in La Jolla, discusses current research and potential future therapies for PD. In 2012, a partnership of scientists, clinicians, PD patients, and patient advocates was formed to develop a therapy for PD using patients' own skin cells that can be transformed into dopamine neurons, which can then be transplanted to their brains to restore lost cells. With further support from the foundation and granting agencies, the research and clinical partners hope to transplant cells to the first patient in about three years. This kind of partnership is unprecedented, and is inspiring for both the researchers and the patients, who are working together to develop the first effective therapy for PD. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 30484]
Bahasa Inggeris
Amerika Syarikat
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EPISOD LAIN DALAM PODCAST INI
Organs renew and repair themselves through stem cell systems that respond to injury, microbes, and local signals. Ophir Klein, M.D., Ph.D., of Cedars-Sinai Medical Center explains how the intestine shifts into regenerative states after injury, how long-term changes in the stem cell niche may sha ...
Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for ...
Cognitive resilience depends on how the brain responds to environment, aging, and inflammation. J. Tiago Gonçalves, Ph.D., studies the hippocampus to examine how spatial memory is shaped by factors such as cognitive enrichment, exercise, social interaction, disease, and age. Gonçalves explains h ...
Stem cell health in space matters for astronaut health and cancer research. Jessica Pham, UC San Diego, explains how spaceflight shapes normal hematopoietic stem cells and cancer stem cells through nano bioreactor studies, astronaut blood analysis, and tumor organoid work in low-Earth orbit. Pha ...
Alpha Clinics in California accelerate the development of regenerative medicine therapies that use cells and genes to treat serious diseases. Patient advocate Tara Radcliffe Ghiglieri shares lived experience with gene therapy, while Sheldon Morris, M.D., M.P.H., Mehrdad Abedi, M.D., Daniela A. B ...
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