MENGENAI EPISOD INI
Your cholesterol is rising even though you take care of yourself, and almost no one has explained that the issue might not be on your plate. I am going to show you where the real regulator of that number is, why it decided to increase it, and what you can start looking at starting tomorrow.
You may have been told that it is age, genetics, or that your metabolism has become lazy. But cholesterol does not travel freely through the blood: it travels inside particles called LDL, and it is the liver that removes them from circulation through doors called LDL receptors. The more open doors, the less cholesterol in your blood work.
And here is the key: those doors are opened by a thyroid hormone, T3. When the thyroid slows down, the key turns with less force, the liver stops replacing doors, and the number goes up no matter how much you have emptied your pantry of fat. It is not that your diet has failed: it is that the thermostat of your engine has slowed down.
This was demonstrated by the teams of Onno Bakker in Amsterdam and Gene Ness in Florida, and was intuited much earlier by a 19th-century surgeon, Theodor Kocher, when he removed thyroids and observed what happened afterward. Today we continue to do something similar: we look at the number and turn off the warning light, instead of asking about the engine.
🎯 Why your cholesterol number does not measure what you think: LDL is the truck, not the cargo
🎯 Where the doors that remove cholesterol from your blood are located, and who opens them
🎯 The thyroid as a thermostat: what happens when it slows down
🎯 Why cholesterol rises even when you eat well (and why fat is not to blame)
🎯 The mistake of turning off the warning light: treating the number without checking the engine
🎯 What you can start observing tomorrow and what you should not expect
Key concepts
cholesterol, LDL, LDL receptors, liver, thyroid, T3, T4, hypothyroidism, metabolic thermostat, TSH, Theodor Kocher
Scientific evidence consulted
Transcriptional regulation of rat hepatic low-density lipoprotein receptor by thyroid hormone.
https://doi.org/10.1006/abbi.1995.0061
Thyroid hormone regulation and cholesterol metabolism are connected through SREBP-2.
https://doi.org/10.1074/jbc.M305417200
📚 All sources for this video, one by one, on the blog: https://iky.eu
💎 This channel exists to remain independent. The members are the ones who make it possible: they have access to a closer community and verified resources, chosen one by one by José María. If you want to take that step:
https://www.youtube.com/channel/UCDUt4dfNs1YD0ELwOx4dPLg/join
TABLE OF CONTENTS:
00:00 The blood test: high cholesterol and guilt
03:40 LDL is not cholesterol: the trucks and the doors
06:37 The thyroid: the master thermostat and T3
11:06 The statin and the dashboard light
16:02 Kocher: goiter, the Nobel Prize, and the lesson
19:22 The symptoms no one looks at
22:19 What to do: changing your perspective
25:51 Three days measuring your thermostat
27:21 The end: the series and medical disclaimer
📺 Watch more about cholesterol in this playlist:
https://www.youtube.com/playlist?list=PLMRmP7CE4kf4
📺 And about energy and fatigue, right here:
https://www.youtube.com/playlist?list=PLM3wb3Lvhd2I
#ColesterolAlto #Thyroid #Longevity
You may have been told that it is age, genetics, or that your metabolism has become lazy. But cholesterol does not travel freely through the blood: it travels inside particles called LDL, and it is the liver that removes them from circulation through doors called LDL receptors. The more open doors, the less cholesterol in your blood work.
And here is the key: those doors are opened by a thyroid hormone, T3. When the thyroid slows down, the key turns with less force, the liver stops replacing doors, and the number goes up no matter how much you have emptied your pantry of fat. It is not that your diet has failed: it is that the thermostat of your engine has slowed down.
This was demonstrated by the teams of Onno Bakker in Amsterdam and Gene Ness in Florida, and was intuited much earlier by a 19th-century surgeon, Theodor Kocher, when he removed thyroids and observed what happened afterward. Today we continue to do something similar: we look at the number and turn off the warning light, instead of asking about the engine.
🎯 Why your cholesterol number does not measure what you think: LDL is the truck, not the cargo
🎯 Where the doors that remove cholesterol from your blood are located, and who opens them
🎯 The thyroid as a thermostat: what happens when it slows down
🎯 Why cholesterol rises even when you eat well (and why fat is not to blame)
🎯 The mistake of turning off the warning light: treating the number without checking the engine
🎯 What you can start observing tomorrow and what you should not expect
Key concepts
cholesterol, LDL, LDL receptors, liver, thyroid, T3, T4, hypothyroidism, metabolic thermostat, TSH, Theodor Kocher
Scientific evidence consulted
Transcriptional regulation of rat hepatic low-density lipoprotein receptor by thyroid hormone.
https://doi.org/10.1006/abbi.1995.0061
Thyroid hormone regulation and cholesterol metabolism are connected through SREBP-2.
https://doi.org/10.1074/jbc.M305417200
📚 All sources for this video, one by one, on the blog: https://iky.eu
💎 This channel exists to remain independent. The members are the ones who make it possible: they have access to a closer community and verified resources, chosen one by one by José María. If you want to take that step:
https://www.youtube.com/channel/UCDUt4dfNs1YD0ELwOx4dPLg/join
TABLE OF CONTENTS:
00:00 The blood test: high cholesterol and guilt
03:40 LDL is not cholesterol: the trucks and the doors
06:37 The thyroid: the master thermostat and T3
11:06 The statin and the dashboard light
16:02 Kocher: goiter, the Nobel Prize, and the lesson
19:22 The symptoms no one looks at
22:19 What to do: changing your perspective
25:51 Three days measuring your thermostat
27:21 The end: the series and medical disclaimer
📺 Watch more about cholesterol in this playlist:
https://www.youtube.com/playlist?list=PLMRmP7CE4kf4
📺 And about energy and fatigue, right here:
https://www.youtube.com/playlist?list=PLM3wb3Lvhd2I
#ColesterolAlto #Thyroid #Longevity
Bahasa Inggeris
Amerika Syarikat
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CARI EPISOD LEPAS
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Penafian: Podcast dan karya seni yang dibenamkan pada halaman ini adalah daripada José María Castillejo, yang merupakan hak milik pemiliknya dan tidak bergabung dengan atau disokong oleh Listen Notes, Inc.
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