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Dr. Refky Nicola speaks with Dr. Lyndon Luk about the principles behind imaging screening programs, including disease selection, diagnostic performance, technical quality, overdiagnosis, and cost effectiveness. Together, they explore how radiologists balance early detection with patient safety, evaluate screening outcomes, manage incidental findings, and prepare for the growing role of artificial intelligence in screening imaging. Screening with Imaging: Principles, TechnicalAspects, and Cost-effectiveness. Luk et al. RadioGraphics 2026; 46(10):e260145.
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