Disruptive: Confronting Sepsis
Sepsis is a bloodstream infection caused by an uncontrolled spread of pathogens and release of toxins that can lead to systemic inflammation and multi-organ failure. Sepsis is the leading cause of hospital deaths and kills at least eight million people worldwide each year. Current treatment is to a…
Free Forum Q&A: Don Ingber - Innovation Inspired by Nature
Originally Aired 5/6/12After 3.8 billion years of R&D on this planet, failures are fossils. What surrounds us in the natural world is what has succeeded. Nature, imaginative by necessity, has already solved many of the problems we are grappling with. Animals, plants, and microbes are the consummate…
Bone Marrow-on-a-Chip
Wyss Institute Founding Director Don Ingber, Postdoctoral Fellow Yu-suke Torisawa, and Researcher Catherine Spina explain how and why a they built bone marrow-on-a-chip, and how they got it to act like whole living marrow and manufacture blood cells. More information: http://wyss.harvard.edu/viewpr…
Bioinspired Approach to Sepsis Therapy
Wyss Institute Founding Director Don Ingber, Senior Staff Scientist Michael Super and Technology Development Fellow Joo Kang explain how they engineered the Mannose-binding lectin (MBL) protein to bind to a wide range of sepsis-causing pathogens and then safely remove the pathogens from the bloodst…
Preventing the Next Pandemic with Organ Chips
In search for strategies to curb pandemics, scientists strive to understand how pathogens slip past the immune system and wreak havoc on the body. To achieve this goal, researchers study viral infection in models that mimic how different cell types interact with each other, the immune system, or th…
Animal Free Labcast #4 - The Pioneer
World-class pioneer of biomedical research and innovation, Dr Don Ingber, is the founding director of Harvard University’s Wyss Institute for Biologically Inspired Engineering.
In 2010, Dr Ingber developed a lung-on-a-chip - the first of its kind - and has continued to lead the field by developing…
Can Humans Be Made on a Microchip?
Get ready to step into the future of biomedical research with the ground-breaking technology of "body-on-a-chip."
In this exciting episode, we chat with Professor Don Ingber, the incredible mind behind this revolutionary technology, to uncover the potential of miniature "organs-on-a-chip".
By li…
Plastic in our blood? That’s a problem.
Our planet is filled with plastic. On average, we produce 430 million tons every year, most of which is used only for a short period of time and then discarded. But plastic isn’t just in the environment: it’s now in our bodies. Microplastics have been found in our bloodstreams, lungs, and other org…
Wet market SARS CoV-2 origins revisited
Last week, the website covid.gov looked very different, containing information on coping with covid and US research. This week it leads you to a White House webpage outlining the lab-leak hypothesis – that the pandemic was the result of dodgy lab work at the Wuhan Institute of Virology. The scienti…
Building the Wyss Institute, Organs-on-Chips, and Fighting for Science — Don Ingber | Frameshifts Episode #9
The future of human biology isn’t about better animal models - it’s about building human organs on chips that think like the body does.
Don Ingber, founding director of Harvard’s Wyss Institute, has one of the most unconventional origin stories in the field. In 1975, as a Yale undergrad, he took a …
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