Commanders vs Colts Week 4 Preview: Matchups & Prediction

Download the Kalshi app and use code ATOZ to get $20 when you trade $20. Kalshi. Trade on anything. Sign up today: Sponsor Disclosure: Kalshi: 18+ only. Restrictions and eligibility requirements apply. Event contract trading involves risk and may not be suitable for all investors. Kalshi products are not available in all jurisdictions. Prices, values, and available markets may differ from those mentioned. For more information see kalshi.com/regulatory. The Washington Commanders head to London for a huge Week 4 matchup against the Indianapolis Colts, and Sean Anderson breaks down the Colts' offense, defense and the biggest matchups Washington needs to win. After Washington's impressive victory over the Seattle Seahawks, Sean believes the Commanders have a favorable opportunity against Indianapolis. In fact, he believes Washington should win this game. The Colts have played some difficult competition, including the Kansas City Chiefs and Baltimore Ravens, but Sean believes Indianapolis has struggled badly on defense and doesn't present the same level of challenge Washington just faced against Seattle. The biggest problem for Indianapolis could be Daniel Jones. Sean explains why he believes Jones can give Washington opportunities to create turnovers and why the Commanders' defense should be looking to take advantage. Washington has already created two interceptions after a strong defensive performance against Seattle, and Sean believes the Commanders can continue that momentum against Jones. Jonathan Taylor is the biggest threat on Indianapolis' offense. Sean believes Washington needs to make Taylor beat them while relying on its massive defensive line to slow down the Colts' rushing attack. The Commanders' defensive line has been one of the most impressive units on the team this season, and Sean believes the size Washington has added up front gives the team a legitimate chance to control the line of scrimmage. Josh Downs is another player Washington needs to account for. Sean believes Downs is one of the better young receivers in the NFL, but he doesn't see much depth behind him in Indianapolis' receiving corps. Tyler Warren could also be a problem. Washington has struggled against tight ends at times this season, and Sean believes Warren is athletic enough to test the Commanders' defense. On the other side of the ball, Indianapolis has some talented individual defenders, including Sauce Gardner, DeForest Buckner and Arden Key. But Sean believes the Colts' defense is nowhere near the level Washington just faced against Seattle. That could create opportunities for Marcus Mariota and Washington's running game. Sean also identifies a potential matchup to watch involving the Colts' rushing defense, which is allowing 141.3 rushing yards per game and 4.9 yards per carry. Could Washington's running backs have a huge game in London? Can Marcus Mariota take advantage of Indianapolis' struggling defense? Will the Commanders force Daniel Jones into turnovers? And can Washington's defensive line slow down Jonathan Taylor? Sean Anderson breaks down everything Washington needs to know before taking on the Colts in Week 4. Subscribe to A to Z Sports Washington Commanders for daily Commanders news, analysis, reactions, predictions and coverage throughout the 2026 NFL season. 0:00 Commanders vs Colts Week 4 Preview 0:53 Indianapolis' Defense Is A Problem 1:12 Daniel Jones Could Give The Game Away 2:20 Jonathan Taylor Is The Biggest Threat 3:05 Washington's Defensive Line 3:41 Josh Downs Is The Colts' Best Receiver 3:56 Tyler Warren Could Cause Problems 4:45 Indianapolis' Offensive Line 5:05 The Colts Defense vs Washington 5:52 Sauce Gardner vs Terry McLaurin 6:13 Why Washington Should Win 7:08 Commanders vs Colts Prediction 7:46 Marcus Mariota Prop Bet 8:22 Why The Commanders SHOULD Win #Commanders #WashingtonCommanders #Colts #NFL #MarcusMariota Make A to Z Sports your preferred source on Google: Play A to Z Sports Daily Games: Subscribe to the channel if you enjoy the content, and hit that like button! Facebook: Instagram: TikTok: Twitter/X: