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Sarah introduces an Evolving Wellness episode on estrogen clearance, perimenopause/menopause, and why estrogen therapy isn’t one-size-fits-all, then interviews John and David from Mera Labs, whose work on sulforaphane began after both of their wives faced breast cancer. They explain how sulforaphane activates NRF2, supporting phase 2/3 detoxification, antioxidant responses, mitochondrial function, and mitophagy, and discuss circadian oscillations of NRF2. Sarah shares her experience of heavy bleeding, PMS, and low ferritin improving after several cycles on their product, with benefits also noted for her autistic teen. The guests differentiate stabilized sulforaphane from glucoraphanin products, describe synergy from added PEITC, discuss dosing timing, toxins/microplastics and endocrine disruptors, DIM questions, stress and vagal regulation, and note a rare microbiome-driven estrogen recycling condition linked to galactorrhea
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Connect with John and David
https://www.instagram.com/themaralabs/
For the next week, Evolving Wellness loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/SARAHK and use code SARAHK at checkout. After one week, the code will return to the standard 15% off.
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Timestamp:
00:00 Microbiome Estrogen Recycling
00:44 Why This Episode Matters
03:14 Podcast Intro and Disclaimers
04:27 Meet the Mera Labs Founders
10:26 Sarah’s Estrogen Clearance Story
14:57 Sulforaphane Science and Nrf2
31:30 DIM vs Sulforaphane Debate
35:09 Minimize Menopause Formula
37:54 Estrogen Therapy Prep
41:58 Stress Epigenetics Reset
44:38 Vagus Nerve Tools
49:42 Sulforaphane Dosing Guide
52:44 Toxins Microplastics Foods
01:05:29 NRF2 Safety Wrap Up
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This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!
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