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What does it really take for a physician to build a successful health tech company—without abandoning clinical medicine?
In this episode of Startup Physicians, Dr. Alison Curfman sits down with Dr. Osama Hashmi, dermatologist, entrepreneur, and CEO of Empiricus, to unpack his unconventional journey from pre-med student to multi-time founder.
Osama shares how early exposure to healthcare policy, liability, and system inefficiencies sparked a deeper curiosity—not just about treating patients, but about changing the systems that shape patient care.
In this episode, we explore:
- Why understanding the problem matters more than understanding technology
- How Osama started his first company before medical school—with no entrepreneurial background
- The myth that physicians must quit medicine to build startups
- Why starting with manual solutions often leads to better technology later
- The difference between services-based businesses and tech startups
- How Empiricus is rethinking physician–pharma communication
- Why founders bring optimism to a healthcare system facing rapid change
- Practical, low-risk ways physicians can explore entrepreneurship today
This conversation is especially valuable for physicians who feel curious—but unsure—about business, startups, or innovation. Osama breaks down complex ideas into approachable, actionable insights and reminds us that you don’t need to be technical, fearless, or all-in to get started.
“Entrepreneurship doesn’t mean leaving medicine. It means using business as a tool to solve real problems.”
Chapters:
00:00 – From Med School Dreams to System-Level Questions
02:55 – Why Business & Capital Drive Real Change in Healthcare
04:35 – Starting a Company Before Medical School
06:45 – How Physicians Actually Get Started in Entrepreneurship
08:40 – Physicians Are Closer to the Real Problems Than Anyone Else
10:55 – Start Manual, Then Add Technology
14:55 – Services vs Tech: Choosing the Right Business Model
15:25 – The Vision Behind Empiricus & DocUpdate
17:30 – Free E-Prescribing & Physician-Centered Tools
19:00 – Why Physician Communities Matter More Than Ever
21:05 – Founders Think Differently About the Future of Medicine
24:45 – You Don’t Have to Quit Medicine to Be an Entrepreneur
26:20 – Practical Advice for Doctors Curious About Startups
28:10 – Building Teams vs Being the Best Individual Performer
Resources & Links
- Impiricus – Ethical pharma–physician engagement ImpiricusHome
- DocUpdate App – Free e-prescribing & physician tools (iOS & Android) DocupdateHome
- Connect with Dr. Osama Hashmi – LinkedinOsama Hashmi MD MPH - Impiricus | LinkedIn
- Startup Physicians Programs & Community – startupphysicians.com
