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In this episode of Communicable, Thomas Tängdén and Rekha Pai Mangalore return for part 2 of the ‘We will make you love PK/PD’ series. In this round, they are joined by Iris Minichmayr (Austria) and Phil Selby (Australia) for a deep dive into how PK/PD data and principles can be used as integral clinical tools to support dosing decisions. They break down technical concepts of pharmacometrics such as population PK models, Monte Carlo simulations, probability of target attainment (PTA), and cumulative fraction of response (CFR), helping to make these approaches more accessible to everyday clinical practice.
This episode was edited by Kathryn Hostettler. The executive producer of Communicable is Angela Huttner.
Further reading
- Tängdén T, et al. Personalised patient management and infection prevention: current evidence and future perspectives. In: ESCMID Global 2025. Available on ESCMID Media: https://media.escmid.org/videos/01K7HWCJAHZ464H3XXK97SZ842
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Communicable E57: PK/PD, part 2
[00:00:00]
Thomas: Hello and welcome back to Communicable, the podcast brought to you by CMI Communications, ESCMID's open access journal covering infectious diseases and clinical microbiology. My name is Thomas T�ngd�n. I'm an infectious disease physician and professor at Uppsala University, Sweden, and an associate editor at CMI Comms.
This is the second episode of our new series on optimal dosing and PK/PD called We Will Make You Love PK/PD. Today, we'll disc…
[00:00:00]
Thomas: Hello and welcome back to Communicable, the podcast brought to you by CMI Communications, ESCMID's open access journal covering infectious diseases and clinical microbiology. My name is Thomas T�ngd�n. I'm an infectious disease physician and professor at Uppsala University, Sweden, and an associate editor at CMI Comms.
This is the second episode of our new series on optimal dosing and PK/PD called We Will Make You Love PK/PD. Today, we'll disc…
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