# Lewy Body
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Lewy bodies are inclusion bodies – abnormal aggregations of protein – that develop inside neurons affected by Parkinson's disease, the lewy body dementias (Parkinson's disease dementia and dementia with Lewy bodies (DLB)), and in several other disorders such as multiple system atrophy. The defining proteinaceous component of Lewy bodies is alpha-synuclein (α-synuclein), which aggregates to form Lewy bodies within neuronal cell bodies, and Lewy neurites in neuronal processes (axons or dendrites). In some disorders, alpha-synuclein also forms aggregates in glial cells that are referred to as 'glial cytoplasmic inclusions'; together, diseases involving Lewy bodies, Lewy neurites and glial cytoplasmic inclusions are called 'synucleinopathies'.
Caring with Compassion: Finding Light in Dementia | Overcoming Certainty
Kimberly Pellicore is the author of A Guide for Lewy Body Dementia Caregivers: Caring with Compassion. Today we discuss the uncertainties that come with the diagnosis of Lewy Body and other dementia related diseases. Kimberly shares her journey through the caregiving process and how God’s light ke…
Suz talks Wise Women & Wine: Alzheimer's Association Fundraiser 4/19/26
How do you transform a personal tragedy into a community-wide movement? Two years ago, Amber Pepito lost her mother to Lewy Body dementia at just 62 years old. Today, the Cal Poly graduate is leading the charge to fund a cure.
We sit down with Amber and Laura DeLoye, Program & Education Manager fo…
Can a Blood Test Detect Alzheimer’s? Understanding Types and Early Signs
Join us as we delve into the intricate world of dementia caregiving with guest Nancy Treaster, a certified caregiving consultant, who co-founded Caregiver's Journey after navigating dementia care within her own family.
Listeners will gain clarity on the distinctions among the major types of dement…
Remembering Ted Turner with Bill Burke; The Case of the Missing Pee-wee Herman Doll
Nostalgia Tonight with Joe Sibilia | 5-17-2026
Monologue:
Joe Sibilia talks about his family's estate sale and the vintage items Joe couldn't sell.
Guest:
Bill Burke, Former General Manager of Turner Classic Movies, Former President of TBS, co-author of Ted Turner's autobiography, "Call Me Ted"…
The Long Goodbye: 15 Years of Loving My Husband Through Dementia
In this deeply moving episode of Dementia Discussions, I sit down with Mary, a beloved member of my Dementia with Lewy Body support group through the UCLA Mary S. Easton Center. Mary shares the remarkable story of her husband, Dan, and their 15-year journey through dementia—a path marked by uncerta…
TB-006- a new treatment for Alzheimer's
What if Alzheimer’s and Parkinson’s weren’t just protein problems—but inflammatory ones?
In this episode of The Recharge Biomedical Podcast, Dr. Edward Park sits down with Dr. William Gael to discuss TB-006, a first-in-class humanized antibody targeting Galectin-3, a key driver of chronic brain inf…
LATE vs Alzheimer's: Biomarkers, Mixed Dementia, and Clinical Realities with Nate Chin & Sterling Johnson
Up until just a couple years ago, an 85-year-old patient presenting with gradual, amnestic memory loss was almost automatically presumed to have Alzheimer's disease. However, new biomakers and the recognition of conditions like Limbic-predominant age-related TDP-43 encephalopathy (LATE) are reshapi…
Lewy Body, Alzheimer’s & Mixed Dementias Explained | Dr. James Galvin
Lewy body dementia is a form of dementia caused by abnormal protein deposits in the brain known as "Lewy bodies,” with symptoms that can resemble those of Parkinson's disease. Leading neurologist Dr. James E. Galvin explains how to identify early warning signs, distinguish Lewy body dementia from A…
Parkinson's Dementia vs Lewy Body vs Alzheimer's
Dr. Patel shares the signs and symptoms to look for when it comes to Lewy Body Dementia, Parkinson's Dementia and Alzheimers. We originally recorded in 2023 as Ep. 80, remastered in 2026 because it's a topic that has come in up recent conversations with friends in the PD community.Subscribe and nev…
Caring for Aging Parents Without Losing Yourself
What if the most loving thing you can say to an aging parent isn’t “I’ll take over”—but “Let’s decide together”?
In this episode, we navigate the emotional and medical realities of elder care with compassion and clarity. Whether you're managing hospital visits, struggling with sibling dynamics, or …
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