WEBVTT
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Bye. Your biology may not be the same in your
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40s as it was in your 20s, but your standards
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and goals can be even bigger. We're at a time
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where we have more tools and methods to not just
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live longer, but also healthier with better results as we age.
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Aging is no longer viewed as a decline. It's about
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optimization and time efficiency. Training smarter and more efficient is
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a new standard, and we now know how to get
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more from the workouts we are already doing. Now, chances
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are your supplement stack is missing a much healthier foundation.
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So enhance it with MitoPure, a targeted supplement that revitalizes
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your mitochondria, the powerhouse of your cells. Mitochondria are crucial
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to overall health, not just energy production. Protein builds muscle.
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Creatine supports power. MitoPure helps support the cellular engines that
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power both. When your cells thrive, everything follows. So claim
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your free aging muscle protocol guide and free sample of
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might appear gummies from timeline at timeline.com slash Dylan. It's
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the science back breakdown of exactly what's happening to your
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muscles as you age and how to fight back. All right, everybody,
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welcome back to the Dylan Gemelli podcast. So, you know,
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one of the huge benefits that you get when you
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interview so many different people is that you get introductions
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you really weren't ready for, weren't aware were coming. And
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that's what happened with me and my guest today. I
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did several interviews there back and forth with Dr. Daniel Pompa,
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and he said, well, I got a couple people I
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think are going to be of significant interest to you.
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And I, of course, I'm going to take his his recommendations.
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But this one in particular stood out to me of
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the ones that he sent me. And I have been
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excited for this interview ever since we talked. And I
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think that you're going to see very quickly as to why. Now,
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my guest today serves as the chief development and science
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officer for Restem Group. And he has extensive knowledge in
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all aspects of cellular biology, regenerative medicine, biology. and the
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key to longevity, maintaining immune health. And he has several
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patents and leads multiple clinical studies, which we're going to
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talk about today because he's got some new information that
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he wants to provide that I can't wait to hear about.
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And I specifically didn't have him tell me so I
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could learn right with you guys in the brand new.
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But he developed an immune-based therapy using natural killer cells
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in the context of longevity. And it demonstrated one of
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the first of its kind methods to reduce immunity immunosenescence
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in humans. And he's also produced a regenerative medicine exosome
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topical that's disrupted the cosmetic rejuvenation space. So we're going
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to get into all this and plenty more. My friends,
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welcome Dr. Rafael Gonzalez. Dylan, thank you for having me here.
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Pleasure to be here and love to educate as you do.
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It's a lot of fun to do, especially when we
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talk about the most important thing in our body, the
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immune system.
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I am so stoked. You know, I've actually had some
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pretty strong discussions.
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Dr.
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Jeffrey Bland and I had a really good one on
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the immune system, Dr. William Lee, all highlighting the importance
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of it. And I know that you have an extreme
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expertise in that. And so my knowledge base is bigger
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than when you and I talked, and I'm ready for
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you to enhance it to the highest extent amongst everything
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else that you talk about. So once again, thanks for
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coming in here to see me. I really value anybody's time,
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especially yours, because I know the extent of where we're
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going today. So let's lead into that with some of
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the discussion on the immune system. But you made it
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very clear in what you just said, the most important.
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Why do you say that? The main reason is because
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every single disease has an immune component to it. Believe
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it or not, and some people say out there, well, no,
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if I have a genetic disease, it does not. No,
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there's an immune component. to the progression of that disease.
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Always is. For a simple example of such is something
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such as pediatric Duchenne muscular dystrophy, which is a devastating
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thing for pediatric kids. It's awful. Yet, if I can
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help control some of the immune destruction in there, I
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can slow down the progression of that disease. That's why
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the immune system is so powerful. There's every single disease.
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Neurological diseases, we take them for granted. It's mostly an
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immune system issue. The immune system has gone awry. It's
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not doing what it's supposed to do. And it causes
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a neurological issue. Would you say that progressively over time
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that immune system health has declined? Significantly. Okay. And why
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would that be? One of the biggest burdens is a
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lot of things. Number one is diet, what's going on,
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what we're being fed, what we're being dealt with on
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a daily basis. Two, the environment is really, really bad.
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And three, your immune system, as you age, every cell
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in your body ages, no matter however you think about it.
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It's something called the Hayflick limit. Every cell in your
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body has a finite amount of divisions, and at some juncture,
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it stops dividing and doesn't do much. This is the
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Hayflick limit. But the biggest problem as you age, and
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you can see this as you're developing is on a
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daily basis, your immune system is challenged. Well, what happened
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six years ago? Six was a six, seven. It's been
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a long time now. Six years ago, COVID.
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Right.
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We got hit with another challenge to our immune system. Yes. Yes.
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And it was a devastating challenge to the immune system.
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And the simple analogy that I talk about a lot
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of times is, listen, the UFC fighter is going to
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beat a standard two, three, four people on the street.
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But when seven, eight, ten people come at him, he's
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not going to win. And it's what happens on a
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regular basis with your immune system. It's really bad because
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you're challenged with daily bacteria. You're challenged with daily mold, toxins, fungus, microplastics,
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which is a nightmare, metals, which are a nightmare, the environment,
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the pollutants, everything. Your immune system has to deal with that.
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And if your immune system gets overwhelmed, it's a big problem.
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The biggest issue we're having is, we go back to
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the COVID, is the virus. And a lot of people
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don't understand. They think a bug is a bug is
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a bug. No. A virus is something that requires a host.
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You are the host while this alien has come into
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you And it's crazy, if you look at images of it,
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it looks like a little spaceship that basically shoots its
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DNA into your cells and then replicates and it lives there.
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So this thing knows ways of, since you're required for
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it to live, it knows ways how to hide and
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how to cause havoc. And if your immune system is
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challenged or you're dealing with, eight, 10 other things, this
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thing is going to be a massive burden. Like there's
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many diseases now and there's more and more evidence coming out,
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especially autoimmune diseases, which are becoming really problematic, not only
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in the US, but worldwide. More and more of them
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are surfacing. More individuals that think they only have rheumatoid
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arthritis have an ankylosis spondylitis, have ulcerative colitis, have all
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these different autoimmune diseases sort of combined in one. It's
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because the immune system has become somewhat hijacked in many instances.
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And the hijacking many times are these viruses, where we
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finally identified at least one so far that is multiple
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sclerosis that is hijacked by Epstein-Barr virus is what causes it.
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So these viruses are what's causing a lot of problems.
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Don't get me wrong. There are good viruses, like there's
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good bacteria that we have to live symbiotically with. But
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the majority of them, specific ones, are really, really bad
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and detrimental to our system.
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What's the direct cause to your cells that then in
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turn weakens the immune system?
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What ends up happening is the immune system, especially in
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the context of an autoimmune disease, it becomes exhausted. You know,
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cells divide and turn over on a regular basis.
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Right.
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Your body, especially when you have an autoimmune disease, your
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body has now saw something as it is foreign. So
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if it sees something as foreign, it goes on to
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overdrive to attack that foreign entity. For instance, in a
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particular disease that we have a clinical study for, it's
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called polymyositis dermatomyositis, myo meaning muscle, muscle, it attacks muscle,
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it attacks skin. Eventually these patients will have issues with
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their lungs because it'll start wiping out lung tissue also.
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which they end up succumbing to the lung portion of
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it because of it. And it sees your own skin,
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your own muscle as foreign. It's killing it. And it's
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on overdrive. It's not balanced. It's not in what's called
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a regulatory state, which is the way your immune system
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is supposed to be. Our body's supposedly consistently in a
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regulated state, which is called homeostasis. And we want to
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be in homeostasis. When the immune system is consistently on
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overdrive and cells are dividing, at some juncture, we talked
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about the first thing we talked about earlier, that hayflake limit,
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the cells are no longer going to be able to
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function correctly. and then the system says well wait a
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second how do i because your immune systems works in
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one particular way it is attack try to remove try
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to eliminate which is inflammation and then to the opposite spectrum,
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which is called a TH1 inflammatory response. And then to
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the opposite spectrum, it has to heal, which is a
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TH2 anti-inflammatory response. But if you have too much of this,
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which is that inflammatory response, this healing cannot respond. It
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can't do anything. The weird thing about the immune system
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is cancer. I was going to ask about that, but
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I'll let you go first. Is cancer. That cancer patient,
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completely opposite from that autoimmune patient, does not mount a
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killing response. That individual that has cancer, we now know,
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has a high amount of regulation, so there's no killing.
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That's one aspect of it, besides the cancer's ability to hide. Right.
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It finds a way to hide, to get away from anything,
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and to do it. but you don't have an appropriate
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mounting killing response. In those patients, you normally have a
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healing response, but you can't heal anything without eliminating it.
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Could you just explain what causes cancer to start like cellularly,
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how it actually begins? There's many, well, there's many different
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things that happen, mostly mutations. So if you think of
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on a daily basis, you go outside, and you're exposed
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to UV light, and you most likely will get a
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mutation in your skin. Your immune system, the first responder
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to that, believe it or not, one of the first
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responders is called the natural killer cell. It is supposed
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to target, it is supposed to eliminate that immediately. That's
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when your immune system's optimized. If it is not, then
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this thing goes unchecked. That unchecked has a possibility, just
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in the context of let's say skin, to go into
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the blood system. What people don't understand is that we're
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not quite there in the technology of the testing aspect.
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Somebody will go and they'll go get a full body scan.
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My body scan is completely clear. The problem is to
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you identify a million cells in a ball and being
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a cell biologist, I see this is a speck on
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a table. There is no technology out there that's really
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going to identify that speck on the table. We have
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to talk about a billion cells in a ball, which
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is the end of my fingertip, which is not much.
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That's a problem. That's something that might be identifiable. But
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even that's a little bit difficult to identify. Because when
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you talk about people have, you know, a millimeter, you know,
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that's what they normally catch is a millimeter, two millimeters,
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a centimeter. You know, a centimeter is billions of cells
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in a ball. It's massive. I know. And then what
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people don't know, the other thing that we don't understand,
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which now they're starting to get a little bit more
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progressive on the testing aspect of it, is looking at
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those cells that are in, like you find in a
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lesion or something like that, those cells that are found
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have the propensity to release cells. And these are called
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circulating tumor cells. And those cells, there's some testing now
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that you can actually detect those, which people are now
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getting smarter, smarter with detections of it. That is the
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problem when you talk about somebody who's had cancer and
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you talk about more than anything else, no evidence of
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disease versus in remission of disease. You couldn't find disease
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versus in remission of disease because you don't really know.
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And it's hard to detect if this stuff has been
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circulating and if it's going to come big comeback. The
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key to all of this is maintaining immune health. Would
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you say in all your years of, of understanding and observation,
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And I think I know the answer, but I want
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to know from you that a weakened immune system will
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make you more susceptible to developing cancer or cancerous cells.
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A thousand percent. Okay. All right.
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So that's why I wanted you to give the full
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explanation of how it got caused and then relate it
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to the immune system in general.
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Yeah. Something in the body has gone awry and the
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immune system hasn't detected it, hasn't killed it. The immune
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system is not working optimally. So if you were say
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around cancer causing aspects, whether, and people can argue what
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those are anymore, but let's just say you're around heavy,
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heavy chemicals that would potentially cause cancer, microplastics, et cetera.
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If you have a very strong immune system, you have
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a far greater chance of not developing cancer as opposed
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to somebody that's got a weakened one or has kind
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of suffered some sort of some alterations with their immune system.
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A thousand percent.
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Yep.
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Okay. Correct. All right. So it's, It's a cellular problem,
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but the immune system is.
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Going to play a huge role into preventing or at
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least mitigating the potential spread or growth of that.
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Yeah, well, the immune system is the one that's got
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to take care of the immune cells, the immune system
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in general, whether it's part of the innate, the immediate response,
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or the secondary response, which is the military. Those have
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to be able to work together and eliminate and kill, regulate,
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and heal. They are the key to recovery. all aspects
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of longevity, including, believe it or not, your skin, what
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your appearance is, whether you look healthy, you're not healthy,
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and it's an issue. And one of the things he
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has talked about, for instance, if you get burdened with
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massive metal toxicity, what does the immune system have to do?
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The immune system has to now go and direct it
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towards that. The entire immune system has to go, especially
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when you're older, has to go and direct it towards that.
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It doesn't even mount a correct short response, like when
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you were young. But what happened to everything else that's
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going on in your body, the other viruses and everything else? Now,
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all of these things are opportunistic. That's where these things,
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you know, surface. The simplest example of this is when
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you look at chickenpox, or when you look at basically,
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you know, the age-associated aspects of chickenpox, which is shingles,
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is it's an opportunistic virus. Your immune system becomes weakened,
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or you have Stress, stress is a killer. You get
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stress and the immune system becomes dampened, weakened. This now surfaces.
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Your immune system has to figure out how to remove
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it to clear it.
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When my dad passed away, my mom got shingles and
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she got psoriasis and those are extremely stress related problems.
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And that weakens your immune system and boom.
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Wow. Okay.
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Now. we kind of covered that cellular side of it.
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I want to shift a little bit now. There's a
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couple of things that I want to get into with
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the immune system, but first you brought up diet. And
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so I want to shift to the problems in our
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everyday diet and how that relates to our immune system.
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Certainly the buildup of inflammation is really the center of
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all diseases. And I'm sure that just rashes our immune system,
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but can you, can you correlate that with the foods
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that we're eating and then maybe touch on some of
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the foods that you would say are are beneficial to
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our immune system and then others that are just destroying it.
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The problem with the.
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Food is the gut houses about 60% of the immune system.
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It's a massive immune component. And what people don't understand,
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if you should know this, is when you eat too
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much or when you eat processed stuff or you eat
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bad stuff, why do you feel, number one is, why
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do you feel sick? It's because there's what's called a
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neural gut access. There's an inflammation that happens in the gut,
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and then it sparks your brain to tell you, I'm sick.
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I need to stop eating. That's another aspect of nausea, vomiting.
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It's telling you, your system is telling you to stop eating.
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When you feel nausea or you don't feel well, your
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system is telling you, stop. Or it's telling you, you
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ate something that's bad. It's a big issue because it
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taps the immune system and puts you in an inflamed state.
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Putting you in an inflamed state is basically trying to
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resolve a gut issue when the immune system should be
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dealing with everything else. It should be dealing with pathogens
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in your vasculature, in your blood system, in your tissue.
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It should be dealing with all of the viruses that
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are there, keeping them at bay. It should be regulating
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the entire system, not focused on the gut. And that's
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one of the things I learned was how the immune
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system works. proportionally was so intertwined into the gut because
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I really wasn't aware of that.
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And that's when I've been getting more into the discussion
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of gut, leaky gut. So I've covered the basis on
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that a lot. But when it comes to learning about
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how it all ties together, I think that you're going
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to have more expertise than anybody that I've talked to
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about that. And that's why my concern with the diet
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especially is leading to so many other problems because now
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I understand it's the tie into the immune system. And
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if you're making your immune system work one direction, you're
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leaving yourself wide open. It's like you're sending all your
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troops one way and there's no army on the other side.
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So if your diet is really bad and it's causing
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you this slew of problems over here, you get a virus,
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you get a COVID, you get something else. My assumption
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is it's a hundred times worse than what it should
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have been.
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Yep. You're going to feel bad. It's going to take
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you longer to recover, especially as you age, because the
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immune system is not functioning correctly. And it's going to be,
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you know, a problem. The process, for me personally, the
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worst thing are the processed breads, carbohydrates. There's probably nothing worse.
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Like here in, at least in the US. I avoid
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bread the only bread I'll eat is like an organic
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sourdough that's the extent of it because I know it
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has you know good bacteria in it it's done well
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but other than that I notice when I touch any
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form of bread I don't feel right I feel off
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there's pastas that are similar There's grains and rice that
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are similar. There's even people talking about oatmeal being good.
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These are oats. Yeah, it's not, you know, all has
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cholesterol benefits. These are oats that tap your gut and
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your microbiome significantly. You know, I just, I focus on
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what's called clean, organic eating as much as possible. Eat clean.
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I'm not a pescatarian, vegetarian, vegan, carnivore. It's an individual thing.
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You might suit well with being a vegetarian. I might
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be an omnivore. I'll eat everything and I switch it
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up and I change it around. I don't, you know,
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I cannot go vegetarian. I don't feel well. I cannot
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go carnivore. I do not feel well. If you don't
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feel well, that diet's not for you. You have to
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find that right fix that you feel homeostatic. You feel
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fine on a daily basis that you're energized and you
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feel well. And the other big thing that nobody focuses
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on is people eat way too late. Yes.
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I used to do it all the time. All the
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time I did. It's you don't understand you sleep for
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a reason. You're sleeping to heal. If you're eating, where's
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all your energy going.
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At nine o'clock at night or eight o'clock at night
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and you went to bed at nine 30 or something
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like that, your food is still digesting and your, your
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body doesn't have that opportunity to heal. You need that
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opportunity to heal. That's what sleeping is for. It helps
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your immune system relax. It helps your gut, your digestive system.
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Your metabolic function, which is so important, has to be
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dimmed down. The other thing is there's only one thing
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that ages you. It's what we just talked about. The
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biggest thing is the Hayflick limit. Cells divide, stop dividing.
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When you eat excessively, what ends up happening? Your liver
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has to process all that. Cells have to divide. Cells
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have to work on overdrive. Cells age. You got to
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cut it down. You got to eat clean. You got
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to cut it down. You know, the focus has always
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got to be diet, sleep, exercise. Yes. If you're not moving,
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you're going to lose it. And the crazy thing about
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it that people don't understand is those are simple. People
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talk about, oh, it costs too much money to live
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longer to do that. No. Those are three things that
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you have full control over. There's no excuses. I blew
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00:22:34.220 --> 00:22:37.680
my knee out. Hey, guess what? I have arms. I
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00:22:37.720 --> 00:22:40.920
can do a cycle with my arms. I can lift
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00:22:40.940 --> 00:22:43.500
with my arms. I can do exercise with my arms.
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I can do breathing exercises. Those are exercises. I don't
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need my knee to do that. Vice versa. I blow
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my arm. I mess up my back. I have legs
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to walk with. These are simple things that anybody could
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do on a daily basis. Set a routine of sleeping
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at a certain time. Stop eating at a certain time.
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You have full control over all that. And that doesn't
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cost you anything. No, I agree. I don't even want
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to tell you how I used to eat late at
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night for so many years. I did the same thing.
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It's terrible. It's absolutely terrible. And then you wonder why
401
00:23:10.289 --> 00:23:12.289
you don't sleep well and don't feel well in the morning.
402
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403
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404
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419
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Yeah.
420
00:24:13.839 --> 00:24:15.880
You know, and it's funny, you brought up the oatmeal.
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So I was like a 15 year, never missed a
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day of oatmeal. And I had several people over years
423
00:24:22.160 --> 00:24:24.180
tell me, you need to cut it out. And you know,
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00:24:24.539 --> 00:24:26.900
you get used to something and they start believing your
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own BS. And I'm a freaking nutritionist. And as soon
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as I stopped eating it, man, I feel so much better.
427
00:24:33.009 --> 00:24:37.019
You know, it makes you feel like heavy. And I don't,
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like you said, there's a lot of things that you
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can do to improve your cholesterol aside from freaking oatmeal,
430
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you know, and you get these people that get so angry.
431
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I told my friend, Ben Azadi, the oatmeal mafia was
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going to come for us because they get so pissed
433
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about it. And it's like, and it's the greatest. I love,
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00:24:52.460 --> 00:24:55.039
you know, he's great. We had a, we had a good, good,
435
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deep conversation that we just studied or sat on oats.
436
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It was great.
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Cause it's, It's a polarizing thing like so many other things.
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But I'm glad you pointed that out. Could you give
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00:25:06.200 --> 00:25:09.220
a few foods that you would recommend for improving your
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immune system that are, you know, and whatever they are,
441
00:25:12.559 --> 00:25:15.029
it doesn't matter what diet it falls under. It's just
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00:25:15.089 --> 00:25:19.470
simply these are good foods for your gut or immune system. Yeah, there's,
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I mean, there's quite a few of them. You can
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discuss some fruit. Things that increase vitamins, like vitamin C,
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vitamin D. Depending on if you can tolerate specific types
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00:25:30.700 --> 00:25:35.230
of dairy, they work well. Things that have, like for instance,
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00:25:35.349 --> 00:25:39.109
probiotics in them are really phenomenal. You know, like yogurt,
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00:25:39.150 --> 00:25:41.970
Greek yogurt is phenomenal. High in protein.
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You know, people that can tolerate the dairy aspect of
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cottage cheese, it's actually another thing that's actually really, really
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00:25:48.190 --> 00:25:57.450
good for you. Specific fruits, things that have strong antioxidants. pomegranates, blueberries, strawberries, raspberry,
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as long as they're organic, because it's crazy. You know,
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00:26:00.509 --> 00:26:02.490
these things are sprayed very, and they're, and they're all,
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they're part of what's called the dirty dozen. You have
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to watch those too. But as long as they're organic
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and they're clean, lean meats are good. As long as
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they're lean, because they provide the basis of proteins, amino acids,
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which our body functions on are really good. Specific fishes,
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00:26:17.579 --> 00:26:19.400
fish you have to be careful with too. Some people
460
00:26:19.420 --> 00:26:21.609
say I stay away from it. busy oceans plagued with
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mercury and there's a bunch of other issues, parasites, but
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eat clean, organic and read what you're doing. And then
463
00:26:27.049 --> 00:26:29.910
ultimately what it boils down to personally, I think is
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how it makes you feel. If you ate something that
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you don't, if somebody told you that something is healthy
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and then you eat it and you didn't feel well,
467
00:26:39.619 --> 00:26:41.960
then it's not for you. Like for instance, I don't
468
00:26:42.220 --> 00:26:46.450
tolerate almonds. And I noticed, I found out actually later
469
00:26:46.470 --> 00:26:49.039
because I love almonds, that it's actually the skin. So
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00:26:49.079 --> 00:26:52.460
I can do a Marcona almond perfectly fine. But if
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I do the other ones, my gut messes up and
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I actually get body aches, which is what's weird too
473
00:26:58.799 --> 00:27:00.849
from it because I don't tolerate it. And there's certain
474
00:27:00.880 --> 00:27:02.789
fishes I know that I can't tolerate either. I don't
475
00:27:02.849 --> 00:27:04.990
eat them. I stay away from them. But, you know,
476
00:27:05.009 --> 00:27:06.789
there's a lot of good eggs are fantastic.
477
00:27:07.089 --> 00:27:07.269
Yeah.
478
00:27:07.329 --> 00:27:09.529
And I love that you said that. And I learned
479
00:27:09.589 --> 00:27:12.299
that with the almonds as well several years ago. But yeah,
480
00:27:12.339 --> 00:27:12.559
I mean.
481
00:27:13.279 --> 00:27:15.400
I was kind of curious too, if, if there was
482
00:27:15.960 --> 00:27:21.160
any like comparison there in terms of is protein better
483
00:27:21.180 --> 00:27:23.400
or fats better or carbs better when it comes to
484
00:27:23.440 --> 00:27:25.579
immune system, or is it just really based on the food?
485
00:27:25.640 --> 00:27:28.740
Not so much the, the macro or micronutrient of it.
486
00:27:29.059 --> 00:27:31.839
You know, what's, what's the funniest thing about it is
487
00:27:32.039 --> 00:27:34.079
you want your immune system to be active, but you
488
00:27:34.119 --> 00:27:37.369
don't want your immune system to be overactive. And this
489
00:27:37.430 --> 00:27:40.210
is sort of, something crazy. So we have, we work
490
00:27:40.230 --> 00:27:43.069
with natural killer cells and we will collect people's blood
491
00:27:43.450 --> 00:27:46.750
to work with it. And the unusual aspect is a
492
00:27:46.769 --> 00:27:49.410
lot of people talk about keto diets and keto diets
493
00:27:49.430 --> 00:27:52.089
are great. Don't get me wrong. But when I get
494
00:27:52.410 --> 00:27:56.329
blood from an individual that's in ketosis, what does ketosis
495
00:27:56.349 --> 00:28:00.150
sort of do? It works great in the context of
496
00:28:00.230 --> 00:28:04.220
maintaining health, but it also puts your system, your immune
497
00:28:04.259 --> 00:28:06.849
system a little bit in a quiescent state. So I
498
00:28:06.930 --> 00:28:11.410
can't grow cells really well. But when I ask somebody,
499
00:28:11.670 --> 00:28:15.390
and we've tested this before, to before I collect your blood,
500
00:28:15.410 --> 00:28:19.109
I need you to do me a favor and have
501
00:28:19.130 --> 00:28:26.039
some yogurt, Greek yogurt, have basically some sourdough toast. Or
502
00:28:26.130 --> 00:28:29.619
bring in some good complex carbohydrates into the picture. Then
503
00:28:29.640 --> 00:28:31.660
I'll grab your blood. Then I have a little bit
504
00:28:31.700 --> 00:28:34.420
more of an active immune system and I can collect better.
505
00:28:35.079 --> 00:28:38.140
So it's something that we've noticed with it. It is
506
00:28:38.220 --> 00:28:44.210
diet specific. Individuals that do too much carnivore in the
507
00:28:44.250 --> 00:28:47.710
context of the immune system too, you have to watch that.
508
00:28:48.269 --> 00:28:51.430
Although it's done one important thing, you will have people
509
00:28:51.450 --> 00:28:55.640
with autoimmune diseases that'll go strictly carnivore. Those people that
510
00:28:55.680 --> 00:29:01.039
go strictly carnivore with autoimmune diseases do really well because
511
00:29:01.079 --> 00:29:04.900
it quiesses the immune system. It's very subjective. That is
512
00:29:04.920 --> 00:29:05.779
a down. Yeah.
513
00:29:05.960 --> 00:29:06.240
Yeah.
514
00:29:06.339 --> 00:29:08.119
But if you want something that's going to make your
515
00:29:08.140 --> 00:29:12.559
immune system more active, you need to introduce complex carbs
516
00:29:12.619 --> 00:29:15.420
and good carbs to it. So going with that, I'm
517
00:29:15.529 --> 00:29:21.089
not specific to any specific type of diet. Like for instance, keto, carnivore,
518
00:29:21.809 --> 00:29:24.029
they're all different and they're dependent on you. I eat
519
00:29:24.329 --> 00:29:27.910
all foods, all different types. I switch it up. I'll
520
00:29:27.950 --> 00:29:30.569
go different depending on, you know, what I want. And
521
00:29:30.609 --> 00:29:36.470
the reason why... I'm not specific on being vegetarian, on ketogenic,
522
00:29:36.670 --> 00:29:39.130
on any of those is because when I looked at
523
00:29:39.190 --> 00:29:42.450
senescence and when I looked at immune function in patients
524
00:29:42.490 --> 00:29:48.549
from blood, I've seen that if I have an individual
525
00:29:48.930 --> 00:29:51.799
that is on ketosis for too long and I pull
526
00:29:51.839 --> 00:29:55.700
his blood, and this makes complete sense, I pull their blood,
527
00:29:56.460 --> 00:30:00.160
their NK cells are not that active. But it's like
528
00:30:00.200 --> 00:30:02.859
that for a reason. And it's like that for a
529
00:30:03.019 --> 00:30:07.740
good reason because the immune system is somewhat quiescent. It's healthy,
530
00:30:07.900 --> 00:30:10.960
but it's quiescent. But when I want to remove and
531
00:30:11.000 --> 00:30:13.920
eliminate senescence, I need something that's a little bit more
532
00:30:14.099 --> 00:30:17.500
active that I can grow. That's why I tell individuals
533
00:30:17.519 --> 00:30:19.480
when we're going to go collect their blood is I
534
00:30:19.519 --> 00:30:22.180
tell them, please do me a favor and eat something
535
00:30:22.240 --> 00:30:25.180
like an organic sourdough bread, which is the only type
536
00:30:25.220 --> 00:30:26.700
of bread that I would eat here in the United
537
00:30:26.740 --> 00:30:30.369
States because the other one's serve, they're bad. They're really
538
00:30:30.410 --> 00:30:32.089
bad for you. A lot of stuff here in the U.S.
539
00:30:32.130 --> 00:30:35.069
is really bad for you. Eat some eggs. Eat some
540
00:30:35.190 --> 00:30:39.349
complex carbohydrates. Ones that are good. Ones that are organic.
541
00:30:39.990 --> 00:30:43.039
Ones that are not bad. I talk about, you know,
542
00:30:43.059 --> 00:30:45.380
the oatmeal's are bad. Stuff like that is people do
543
00:30:45.400 --> 00:30:49.380
not understand. Even, you know, I went to a conference
544
00:30:49.599 --> 00:30:55.099
on autism and pediatric disorders and it's crazy what I
545
00:30:55.140 --> 00:30:59.509
learned there because a lot of people, including me, I
546
00:30:59.589 --> 00:31:05.460
thought that grain rice and all these rices were good. No,
547
00:31:05.500 --> 00:31:08.519
they're loaded with arsenic. I tell you to stay away
548
00:31:08.559 --> 00:31:10.099
from those. The only type of rice you should be
549
00:31:10.180 --> 00:31:13.619
eating for kids that have autism, that have cerebral palsy,
550
00:31:13.640 --> 00:31:19.450
that have all these different issues, are California-grade white rice
551
00:31:19.990 --> 00:31:24.950
or sushi-grade white rice. That's the extent of it. But those,
552
00:31:25.029 --> 00:31:27.980
if you think of the context of longevity, those are
553
00:31:28.000 --> 00:31:31.339
not good for you because... They convert to sugars a
554
00:31:31.380 --> 00:31:33.680
lot too. So that's why we discuss avoiding them as
555
00:31:33.720 --> 00:31:37.109
we age. We discuss avoiding them. But I'm more focused
556
00:31:37.119 --> 00:31:41.630
on eating everything, switching it up. For me personally, I
557
00:31:41.670 --> 00:31:44.910
can't stay on a vegetarian diet. I can't stay on
558
00:31:44.930 --> 00:31:47.250
a carnivore diet. I don't feel well on all of them.
559
00:31:47.410 --> 00:31:51.109
I switch it up. I can't eat almonds. I found
560
00:31:51.170 --> 00:31:53.250
out I can't eat almonds. I removed the skin from them.
561
00:31:53.289 --> 00:31:54.730
I found out after I can eat more corn because
562
00:31:54.769 --> 00:31:57.190
I love almonds. It would cause me pain, cause me
563
00:31:57.210 --> 00:32:00.619
gut issues. So- Some fishes I don't eat. Lean meats
564
00:32:00.680 --> 00:32:03.869
I love. Lean meats, I'll eat them as long as
565
00:32:03.890 --> 00:32:06.809
they're clean, they're good for you. And it's the way
566
00:32:06.849 --> 00:32:08.809
I feel good. And then the big thing is always,
567
00:32:08.849 --> 00:32:11.430
like we talked about earlier, is stop eating at a
568
00:32:11.750 --> 00:32:13.769
certain time frame. Yeah. To go to sleep.
569
00:32:13.930 --> 00:32:16.809
Yeah. Oh, yeah. And I found some blockage in my
570
00:32:16.849 --> 00:32:18.880
heart that I talked to you about on the phone prior,
571
00:32:18.940 --> 00:32:21.539
and I implemented pomegranates. I used to try to help
572
00:32:21.619 --> 00:32:25.900
reverse plaque or at least stabilize and help, but pomegranates also...
573
00:32:26.480 --> 00:32:28.349
And I know this from, like I told you, I
574
00:32:28.390 --> 00:32:30.950
worked with Timeline, which made me study cellular health. But
575
00:32:30.970 --> 00:32:34.779
the pomegranates then relates to urolithin A, which is something
576
00:32:34.799 --> 00:32:37.240
that I use and have come to the understanding of
577
00:32:37.299 --> 00:32:42.039
stimulating mitophagy. So we talked about, you know, different aspects
578
00:32:42.400 --> 00:32:46.509
of cellular health and care. Do you think pomegranates serve
579
00:32:46.529 --> 00:32:49.849
that purpose well too in cellular health? Aside from our
580
00:32:49.869 --> 00:32:52.509
immune system, I'm looking this more on a cellular side.
581
00:32:52.630 --> 00:32:55.730
Is that something that you would recommend for cellular health?
582
00:32:55.730 --> 00:32:57.710
100% because, I mean, I know people that just focus
583
00:32:57.750 --> 00:32:58.829
on pomegranate. Yeah.
584
00:32:59.029 --> 00:33:04.569
Because it's so high in antioxidants. Oxidation is what causes inflammation. Right.
585
00:33:05.049 --> 00:33:07.630
And we all know that. And this is a preemptive
586
00:33:07.990 --> 00:33:12.210
cursor to inflammation is oxidation. The formation of free radicals,
587
00:33:13.470 --> 00:33:17.140
If you reduce them, which is what berries and especially
588
00:33:17.259 --> 00:33:20.960
pomegranate does, you will keep the immune system that it
589
00:33:21.119 --> 00:33:23.000
has an ability to do what it needs to do.
590
00:33:23.420 --> 00:33:23.829
I love it.
591
00:33:24.119 --> 00:33:26.710
Here's the thing, though, that sucks, like you said, is
592
00:33:26.849 --> 00:33:28.890
a lot of these are dirty dozen or they're sprayed
593
00:33:28.950 --> 00:33:31.170
and it's like you're eating these that are supposed to
594
00:33:31.230 --> 00:33:33.549
serve you a purpose and they're actually causing you an
595
00:33:33.650 --> 00:33:36.269
adverse effect if you're not eating the right ones, right?
596
00:33:36.789 --> 00:33:39.369
So we got to be careful on when you and
597
00:33:39.430 --> 00:33:41.650
I say that, and I always preface it just like
598
00:33:41.690 --> 00:33:43.519
you do, make sure they're organic, make sure they're as
599
00:33:43.579 --> 00:33:46.339
clean as you can possibly get, because otherwise you're really
600
00:33:46.519 --> 00:33:49.019
actually causing more problem by what you think you were
601
00:33:49.059 --> 00:33:52.500
doing right, you know, and it sucks that we're involved
602
00:33:52.539 --> 00:33:54.980
in that and around it. But one of the things
603
00:33:55.049 --> 00:33:56.970
I wanted to ask you, because you brought this up
604
00:33:57.029 --> 00:34:00.630
about looking at blood work, because everything I do revolves
605
00:34:00.670 --> 00:34:02.890
around data, blood panels, everything. I do a lot of
606
00:34:02.910 --> 00:34:07.299
hormone optimization. So if we're looking at judging or gauging
607
00:34:07.500 --> 00:34:11.440
a healthy or unhealthy immune system. What blood markers are
608
00:34:11.460 --> 00:34:13.500
we looking for that could potentially be off that might
609
00:34:13.559 --> 00:34:15.199
indicate your immune system screwed up?
610
00:34:15.519 --> 00:34:18.980
I published a paper in 2015 on this, on aging
611
00:34:19.139 --> 00:34:22.960
and the immune system. And the three important ones are,
612
00:34:23.139 --> 00:34:24.480
one of them is not that easy to access, but
613
00:34:24.500 --> 00:34:27.739
you can get it, is high sensitivity CRP. Very easy
614
00:34:27.780 --> 00:34:30.449
to test. Probably the most important one. The second one
615
00:34:30.610 --> 00:34:33.650
is tumor necrosis factor alpha. Tumor necrosis factor alpha is
616
00:34:33.690 --> 00:34:38.030
indicative of A chronic inflammatory state, a state of not
617
00:34:38.110 --> 00:34:41.230
functioning correctly. That's why actually there's a drug out there
618
00:34:41.329 --> 00:34:44.550
for autoimmune diseases that cuts that off. The problem with
619
00:34:44.610 --> 00:34:48.119
cutting tumor necrosis factor out is basically alpha out is
620
00:34:48.340 --> 00:34:51.039
you put yourself in an immune suppressed state. You put
621
00:34:51.059 --> 00:34:54.599
yourself more susceptible to the big C word cancer we
622
00:34:54.619 --> 00:34:57.820
talked about earlier. And that's a bad one. The last
623
00:34:57.900 --> 00:35:00.920
one is interleukin-6. The IL-6 is a lot harder to
624
00:35:01.139 --> 00:35:03.739
test too, but you can go out there, there's tests
625
00:35:03.780 --> 00:35:06.989
available that you can actually look at it because those
626
00:35:07.090 --> 00:35:12.809
three are indicative of age-associated diseases. And there's thousands, there's
627
00:35:12.849 --> 00:35:15.809
a ton of papers out there, published peer-reviewed data on
628
00:35:16.269 --> 00:35:21.769
thousands of patients that if these are inflamed, you are
629
00:35:22.110 --> 00:35:25.769
either in or you're heading towards a neurodegenerative disease or
630
00:35:25.809 --> 00:35:26.909
a cardiovascular disease.
631
00:35:27.570 --> 00:35:30.449
Yeah, it's wild how every single thing that you're looking
632
00:35:30.489 --> 00:35:34.469
for revolves around inflammation. It seems like every single problem,
633
00:35:34.539 --> 00:35:38.400
if you're looking for an indicator, that the high-sensitivity C-reactive
634
00:35:38.420 --> 00:35:39.719
protein tells you a lot.
635
00:35:39.940 --> 00:35:42.420
Yep, it tells you a ton. And there's, you know,
636
00:35:42.460 --> 00:35:45.440
other simple ones is you can look at a sedimentation rate,
637
00:35:46.219 --> 00:35:49.719
you can look at fibrinogen, And you can look at homocysteine.
638
00:35:49.760 --> 00:35:52.420
Homocysteine is too a big one that people don't spend
639
00:35:52.460 --> 00:35:54.659
enough time testing and looking at too. If you look
640
00:35:54.699 --> 00:35:57.929
at those, all of those together, you got a complete
641
00:35:58.119 --> 00:36:00.409
package of some good blood work. And then the other
642
00:36:00.429 --> 00:36:02.630
thing is understanding is that if they tell you you're
643
00:36:02.650 --> 00:36:04.750
within range, where are you at within that range? Because
644
00:36:04.789 --> 00:36:08.409
blood exams have this massive range of individuals that are
645
00:36:08.449 --> 00:36:11.880
really young and individuals that are really old. Well, guess what?
646
00:36:11.909 --> 00:36:15.679
If you're 40 years old and, or 45 years old,
647
00:36:15.800 --> 00:36:18.800
and you're close to the top of that range, something's
648
00:36:18.820 --> 00:36:19.480
not quite right.
649
00:36:19.519 --> 00:36:21.980
You shouldn't be there. And the way they judge these
650
00:36:22.079 --> 00:36:24.079
ranges anymore. And once again, cause I do a lot
651
00:36:24.119 --> 00:36:26.769
of stuff with testosterone for men and women, and some
652
00:36:26.789 --> 00:36:29.269
of these ranges are just out of fricking control.
653
00:36:29.349 --> 00:36:30.250
It makes me mad.
654
00:36:30.849 --> 00:36:33.750
I mean, telling somebody that you're functionable or doing good
655
00:36:33.769 --> 00:36:36.949
with like 190 or 200 testosterone level is just out
656
00:36:36.969 --> 00:36:39.420
of line. And I'm wondering how do they, how do
657
00:36:39.460 --> 00:36:43.449
they gauge? And because you know this, they're constantly changing
658
00:36:43.489 --> 00:36:45.809
the ratios and where you fall. How are they gauging
659
00:36:45.849 --> 00:36:48.579
this and coming up with what falls into being acceptable
660
00:36:49.159 --> 00:36:49.539
in range?
661
00:36:49.760 --> 00:36:53.039
Well, I mean, it's all age. They've gone through all
662
00:36:53.059 --> 00:36:55.820
the way from pediatric adults and they come up with
663
00:36:55.840 --> 00:36:58.820
the reference range. And that's where they'll gauge you between, well,
664
00:36:58.840 --> 00:37:01.909
you're somewhere between here, you're healthy. Based on these individuals
665
00:37:01.949 --> 00:37:05.610
being relatively healthy, anything out of this range, you're not healthy.
666
00:37:05.670 --> 00:37:08.190
But exactly what you just said, I don't want to
667
00:37:08.230 --> 00:37:10.969
be a 50 or a six, I'm a six, I'm
668
00:37:10.969 --> 00:37:13.050
60 years old. I don't want to be 60 and
669
00:37:13.110 --> 00:37:17.130
have the testosterone of 150 because they're telling me you're
670
00:37:17.170 --> 00:37:20.309
within your age. I want to be feeling like my
671
00:37:20.349 --> 00:37:22.030
testosterone is when I was 30.
672
00:37:22.030 --> 00:37:22.309
Yeah.
673
00:37:22.469 --> 00:37:24.530
When I was 35, 40, like that's when I want
674
00:37:24.550 --> 00:37:26.369
to be, I want to be in that range. And
675
00:37:26.409 --> 00:37:29.389
that's a healthier range, I believe for me to sustain
676
00:37:29.869 --> 00:37:32.739
that youthfulness. That's, it's the same thing with the testing.
677
00:37:33.110 --> 00:37:34.739
You want to be in a better range. It's one
678
00:37:34.760 --> 00:37:37.289
that you want it a little bit more pinpointed in
679
00:37:37.329 --> 00:37:41.289
that median area where it's a safer bet to look at.
680
00:37:42.449 --> 00:37:44.570
Okay, I'm going to shift here. I'm going to ask
681
00:37:44.610 --> 00:37:46.300
you a number here, and I'm sure you know it.
682
00:37:47.019 --> 00:37:48.960
And this is one of the things that just fascinated
683
00:37:49.000 --> 00:37:50.940
the hell out of me when I really put my
684
00:37:51.119 --> 00:37:54.320
efforts into studying more biology and cellular biology.
685
00:37:54.719 --> 00:37:57.340
How many cells do we have in our body? I
686
00:37:57.380 --> 00:37:59.840
don't know the exact number. It's trillions. It's trillions, yeah.
687
00:37:59.920 --> 00:38:03.739
It's insane. It's an insane number of cells, because if
688
00:38:03.780 --> 00:38:08.199
you think of just in... In blood flow, apoptosis, natural
689
00:38:08.219 --> 00:38:14.239
cell death, happens about 300 billion times a day. So
690
00:38:14.449 --> 00:38:17.239
it's trillions and trillions. I believe in the brain alone,
691
00:38:17.260 --> 00:38:22.710
a trillion cells. There's an insane amount of cells and
692
00:38:22.909 --> 00:38:26.889
the complex processes of cells in our body that happens
693
00:38:26.949 --> 00:38:32.050
on a daily basis to maintain that appropriate temperature, that
694
00:38:32.070 --> 00:38:35.300
appropriate pH, It's this crazy.
695
00:38:35.539 --> 00:38:37.719
When I started to look at science more of like
696
00:38:37.760 --> 00:38:41.650
this was God's design as opposed to me misconstruing everything
697
00:38:41.670 --> 00:38:43.789
that it was. And I realized the intricacy of how
698
00:38:43.869 --> 00:38:47.889
detailed our body is put together and understanding that structure
699
00:38:48.090 --> 00:38:52.409
and what it goes through on a second by second basis.
700
00:38:52.449 --> 00:38:53.969
I don't even want to say a daily basis, like
701
00:38:54.110 --> 00:38:56.860
every second from the heart to the cells to everything else.
702
00:38:56.940 --> 00:39:00.820
I mean, it is absolutely mind blowing. And learning about
703
00:39:00.980 --> 00:39:04.349
cell structure and understanding their health is everything. And that's
704
00:39:04.409 --> 00:39:08.989
why we talked about, you know, different cellular health aspects.
705
00:39:09.050 --> 00:39:12.150
And people don't understand what a cell goes through, how
706
00:39:12.230 --> 00:39:14.670
it dies or how it becomes a zombie cell or
707
00:39:14.730 --> 00:39:18.000
sticks around and how when those are off and that
708
00:39:18.079 --> 00:39:21.699
function is off, we're off. Right. So like, for instance, mitochondria,
709
00:39:21.699 --> 00:39:24.199
how important is mitochondria as part of a cell?
710
00:39:24.199 --> 00:39:24.909
And do me this.
711
00:39:24.909 --> 00:39:27.809
Because I'm curious, because that's kind of the big thing
712
00:39:27.809 --> 00:39:30.469
is to talk about mitochondria. and I think rightfully so.
713
00:39:30.530 --> 00:39:32.780
But what are the most important parts of a cell?
714
00:39:32.800 --> 00:39:35.179
Because to me, the cellular membrane would be one of
715
00:39:35.199 --> 00:39:37.409
the most important parts. I mean, isn't that protecting it?
716
00:39:37.639 --> 00:39:40.519
So please, break down a cell structure and what's the
717
00:39:40.579 --> 00:39:42.280
most important parts and how we keep it safe.
718
00:39:42.739 --> 00:39:45.940
I can't... It's really hard to say what's the most
719
00:39:46.000 --> 00:39:50.469
important part because the cell... has a machinery in it
720
00:39:50.849 --> 00:39:54.789
and the cell has to produce proteins, has to be
721
00:39:54.829 --> 00:40:00.769
able to produce functional signaling, functional cues, you know, these
722
00:40:00.809 --> 00:40:03.170
little particles that are called endosomes inside of a cell.
723
00:40:03.630 --> 00:40:07.300
A cell produces a signal for another cell and it's
724
00:40:07.519 --> 00:40:11.179
enveloped in a small type of a membrane and then
725
00:40:11.260 --> 00:40:13.820
it's shot out. And this is how we get long
726
00:40:13.860 --> 00:40:16.900
distance signaling from one cell to another cell. That's really important.
727
00:40:16.940 --> 00:40:18.820
That's the importance of the cell membrane because the cell
728
00:40:18.860 --> 00:40:21.800
membrane is that lipid bilayer. But the mitochondria is the
729
00:40:21.840 --> 00:40:25.000
powerhouse of the cell. Mitochondria is really, really important. The
730
00:40:25.059 --> 00:40:28.760
ribosomes are really, really important. The endoplasmic reticular is really,
731
00:40:28.780 --> 00:40:32.860
really important. All of it has function for protein and
732
00:40:32.980 --> 00:40:38.170
for machinery to sustain life. So the purpose of, you know,
733
00:40:38.179 --> 00:40:39.989
the cells have to turn over on a regular basis
734
00:40:40.030 --> 00:40:42.570
because when a cell doesn't become or if it's not
735
00:40:42.630 --> 00:40:45.630
functioning correctly, it has to naturally turn over. And this
736
00:40:45.670 --> 00:40:49.840
is apoptosis. You know, it has to transpire. It transpires
737
00:40:49.889 --> 00:40:52.739
on a daily basis because it has to. It needs
738
00:40:53.260 --> 00:40:55.039
the correct cells to function appropriately.
739
00:40:55.679 --> 00:40:59.300
Every single cell has all of these important components and structure,
740
00:40:59.320 --> 00:41:01.719
and we got trillions of them. So to think about
741
00:41:01.800 --> 00:41:03.699
what it takes for a cell to function and how
742
00:41:03.739 --> 00:41:06.179
many moving parts there are and how many things we
743
00:41:06.219 --> 00:41:09.139
have to be aware of. So how difficult is it
744
00:41:09.199 --> 00:41:12.610
for us to, the duration of our life to keep
745
00:41:12.690 --> 00:41:16.469
cellular health. I mean, how difficult is that? How important
746
00:41:16.530 --> 00:41:18.730
is that as we age? It's one of the most
747
00:41:18.789 --> 00:41:19.550
important things.
748
00:41:20.449 --> 00:41:21.570
You know, that's why a lot of times we go
749
00:41:21.610 --> 00:41:25.500
back to diet is, you know, one of the only
750
00:41:25.559 --> 00:41:28.760
things that preserves longevity and that we know in the
751
00:41:28.800 --> 00:41:32.820
context of telomeres is basically caloric restriction. And if you
752
00:41:32.880 --> 00:41:35.670
stop eating, you slow down cell division. Believe it or not,
753
00:41:35.690 --> 00:41:40.090
it even decreases IGF, which causes cells to proliferate. It
754
00:41:40.139 --> 00:41:45.809
slows down that process. If you think of animal species
755
00:41:45.829 --> 00:41:49.349
that live long time, what do those animals do? Like turtles,
756
00:41:49.550 --> 00:41:55.179
Darwin turtles. These turtles basically sleep a ton. They eat
757
00:41:55.300 --> 00:41:58.760
very little. And this preserves a long lifespan for them.
758
00:41:58.960 --> 00:42:01.719
Slow and steady, just like the turtle. Slow and steady.
759
00:42:01.880 --> 00:42:06.239
It's very, very similar in the human being of slow
760
00:42:06.280 --> 00:42:09.690
down internally. I'm not talking about stopping exercise or anything.
761
00:42:10.119 --> 00:42:14.659
I'm talking about slowing down internally what's transpiring and that's
762
00:42:14.739 --> 00:42:18.960
done by eating correctly, watching what you're consuming on a
763
00:42:19.019 --> 00:42:24.840
regular basis, sleeping correctly because sleep is the ability to recover.
764
00:42:25.039 --> 00:42:28.199
You have to understand that aspect of it. People that
765
00:42:28.219 --> 00:42:32.960
complain to me about spending money on mattresses, I'm like, no,
766
00:42:33.400 --> 00:42:35.719
double down on having the best mattress you can get
767
00:42:35.840 --> 00:42:38.099
and the best sleep you can get because you need
768
00:42:38.119 --> 00:42:41.429
that for recovery. That is part of longevity that's part
769
00:42:41.469 --> 00:42:43.630
of living well you're not going to recover if you
770
00:42:43.650 --> 00:42:45.869
don't sleep well if you don't eat well you're not
771
00:42:45.889 --> 00:42:48.289
going to recover correctly you're going to feel like.
772
00:42:48.230 --> 00:42:50.389
Crap because it affects your immune system and i've come
773
00:42:50.429 --> 00:42:53.050
to understand this by being a person that never takes
774
00:42:53.090 --> 00:42:55.809
a break or never rests is how important that is
775
00:42:56.449 --> 00:43:01.230
to your vitality your inflammation everything so spending money on
776
00:43:01.250 --> 00:43:03.150
the mattress would make the most sense because you use
777
00:43:03.170 --> 00:43:07.440
it the most forever so man you Some of the
778
00:43:07.500 --> 00:43:09.900
points you bring up may seem obvious at times, but
779
00:43:09.920 --> 00:43:11.980
they're the most important things. And you hit the nail,
780
00:43:12.000 --> 00:43:12.940
like every single time.
781
00:43:12.980 --> 00:43:14.250
I love it, dude. I love it.
782
00:43:15.460 --> 00:43:19.239
So that one more part of cells before we move on,
783
00:43:19.239 --> 00:43:21.099
because I know you had some new studies that you
784
00:43:21.119 --> 00:43:22.860
wanted to talk about, but I would just like to
785
00:43:22.900 --> 00:43:27.119
give a small little breakdown. You know, there's, there's supplements
786
00:43:27.159 --> 00:43:29.250
we can take for cellular health. There's things that we
787
00:43:29.289 --> 00:43:33.170
can do, but I think the understanding.
788
00:43:32.590 --> 00:43:33.429
Is what's missing.
789
00:43:33.809 --> 00:43:36.190
Right? And everybody just wants to take a supplement to
790
00:43:36.230 --> 00:43:39.469
fix this or fix that. Just a simple, you know,
791
00:43:39.489 --> 00:43:43.719
we know like fasting, you said stimulates autophagy. How do
792
00:43:43.739 --> 00:43:47.780
we stimulate mitophagy? How do we stop senescence or mitigate it?
793
00:43:47.840 --> 00:43:51.219
You know, what can we do to take control early on?
794
00:43:51.239 --> 00:43:54.369
Because I'm a big try to tackle this early before
795
00:43:54.409 --> 00:43:57.409
it gets too late guy. So give us some of
796
00:43:57.469 --> 00:44:00.030
your plans or insights on how to keep this going.
797
00:44:00.250 --> 00:44:02.030
Being proactive versus being reactive.
798
00:44:02.090 --> 00:44:07.769
Yes. Basically, Important aspect is fasting is good because fasting
799
00:44:07.909 --> 00:44:11.090
activates autophagy and it gives the body a break. Autophagy
800
00:44:11.690 --> 00:44:15.110
gets rid of those bad signals, those bad things that
801
00:44:15.130 --> 00:44:18.349
are released by those zombie cells, those senescent cells that
802
00:44:18.369 --> 00:44:22.230
are there that cause more havoc. The reason why we
803
00:44:22.289 --> 00:44:24.590
know that those signals are bad is for instance, in
804
00:44:24.630 --> 00:44:27.469
a Petri dish and in our lab, we've done this experiment.
805
00:44:27.949 --> 00:44:31.190
If I mix a zombie, the senescent cell with a
806
00:44:31.289 --> 00:44:34.510
very young cell and I mix it together, what I get,
807
00:44:34.630 --> 00:44:37.570
the physical aspect, what's called the phenotype, the feature I
808
00:44:37.610 --> 00:44:41.130
get from the new cells are old cells. And it's
809
00:44:41.170 --> 00:44:45.300
because those signalers are causing the young cells to become old.
810
00:44:45.800 --> 00:44:49.579
I see. So if we can eliminate that aspect of
811
00:44:49.639 --> 00:44:55.280
some of those signals, which diet helps tremendously, exercise helps tremendously,
812
00:44:56.119 --> 00:44:58.119
there's a lot of things that you can actually do
813
00:44:58.340 --> 00:45:01.739
on a daily basis that really doesn't cost much money
814
00:45:02.059 --> 00:45:05.349
that you can slow down that process of the formation
815
00:45:05.369 --> 00:45:07.909
of senescence, that feeling that you feel bad, you know,
816
00:45:07.929 --> 00:45:11.659
these types of things, even breathing exercises. You know, what
817
00:45:11.679 --> 00:45:14.539
are you doing when you do breathing exercise or what
818
00:45:14.559 --> 00:45:17.699
are you doing when you're sprinting? Why do you feel
819
00:45:17.760 --> 00:45:21.599
so well after you walk or you've sprinted or whatever?
820
00:45:21.880 --> 00:45:25.530
You know why? Because you've increased blood flow through your
821
00:45:25.550 --> 00:45:29.829
body and you've increased your intake of oxygen. I'm going
822
00:45:29.849 --> 00:45:32.130
to give you a I would say rapid fire.
823
00:45:32.150 --> 00:45:33.889
I know it's going to take you a second to
824
00:45:33.989 --> 00:45:36.050
answer these, but I'm going to give you some situations
825
00:45:36.110 --> 00:45:39.550
and scenarios of either things we consume and or do
826
00:45:39.789 --> 00:45:42.239
and practice every day. And you tell me how it
827
00:45:42.300 --> 00:45:45.860
relates to good or bad, like what it does to
828
00:45:45.940 --> 00:45:51.119
our cellular health and maybe in and our immune system, please.
829
00:45:51.139 --> 00:45:53.619
Because I doubt this would be highly beneficial for people
830
00:45:53.659 --> 00:45:56.670
that are doing this shit. Alcohol consumption.
831
00:45:57.289 --> 00:46:03.309
Horrible. It's actually cytotoxic. Cardiac toxic more than anything else,
832
00:46:03.389 --> 00:46:06.090
but it's very cytotoxic for you. It affects your metabolic
833
00:46:06.110 --> 00:46:10.130
function in the liver, which indirectly affects your immune system.
834
00:46:10.409 --> 00:46:12.610
Really bad for you. And it affects your sleep. You
835
00:46:12.650 --> 00:46:14.630
might pass out, fall asleep quickly. You are going to
836
00:46:14.650 --> 00:46:15.000
wake up.
837
00:46:15.010 --> 00:46:17.309
You're going to feel horrible. Taps the hell out of
838
00:46:17.329 --> 00:46:20.769
the liver. Smoking, let's say, cigarettes first.
839
00:46:21.409 --> 00:46:24.769
Cigarettes are basically toxic, completely toxic to the lung, and
840
00:46:24.789 --> 00:46:28.730
then completely toxic to the vasculature system, which then indirectly
841
00:46:28.769 --> 00:46:32.110
affects the immune system also. Smoking in general. I'm even
842
00:46:32.130 --> 00:46:35.099
talking about vaping. That's right. Vaping is bad. All of it.
843
00:46:35.269 --> 00:46:38.260
And any type you're burning something and you're inhaling it,
844
00:46:38.449 --> 00:46:42.389
it's bad. Would that go for marijuana as well? Smoking
845
00:46:42.429 --> 00:46:44.909
marijuana can also be bad for you too. Okay. And
846
00:46:44.929 --> 00:46:47.789
there's more and more studies now coming out with that. Yes. Yeah.
847
00:46:47.849 --> 00:46:49.190
I was one of those that used to try to
848
00:46:49.230 --> 00:46:51.980
tell myself it was okay when I finally realized.
849
00:46:51.679 --> 00:46:52.420
That was bullshit.
850
00:46:52.519 --> 00:46:54.559
But you know, that was, that's one of those things
851
00:46:54.579 --> 00:46:56.679
you convince yourself because you're doing something. So I was
852
00:46:56.719 --> 00:47:01.199
curious about your thought on that. What about pharmaceutical drugs.
853
00:47:02.980 --> 00:47:07.099
And I'm talking, we're talking, let me clarify that. The
854
00:47:07.260 --> 00:47:10.809
pharmaceutical drugs that are narcotic type drugs, like your Vicodins,
855
00:47:10.829 --> 00:47:13.690
your Percocets, you know, things that people abuse, Xanax, some
856
00:47:13.730 --> 00:47:14.690
of those types of things.
857
00:47:14.869 --> 00:47:19.610
Horrible for you. Dependent, temporary master problem, don't deal with
858
00:47:19.670 --> 00:47:23.280
any problem, and cause a ton of secondary effects. When
859
00:47:23.300 --> 00:47:25.739
we talk about secondary effects, we talk about liver toxicity,
860
00:47:25.800 --> 00:47:29.800
we talk about kidney toxicity, cardiovascular toxicity also. in the
861
00:47:29.860 --> 00:47:35.440
vast majority of all of those. Some pharmaceuticals are okay,
862
00:47:35.559 --> 00:47:39.619
but the vast majority out there are basically relatively, you know,
863
00:47:40.079 --> 00:47:41.840
they're bad for you. Some people have to be on
864
00:47:41.889 --> 00:47:44.929
them because of specific diseases and it's ultimately a balance
865
00:47:44.969 --> 00:47:47.269
of quality of life or not. But you have to
866
00:47:47.309 --> 00:47:49.750
look at that balance of what is the trade-off. For instance,
867
00:47:49.769 --> 00:47:52.289
in the context of autoimmune diseases, the majority of them
868
00:47:52.710 --> 00:47:55.849
suppress the immune system. The secondary effect of suppressing the
869
00:47:55.869 --> 00:48:00.679
immune system is basically cancer, other infectious diseases, et cetera,
870
00:48:00.699 --> 00:48:04.860
et cetera. Pick your poison. Tylenol. Bad because, I got
871
00:48:04.900 --> 00:48:11.449
a little story. Well, bad because, so it may possibly
872
00:48:11.530 --> 00:48:17.269
resolve a headache, but it is very kidney toxic and
873
00:48:17.570 --> 00:48:20.010
liver toxic. So much so that I'm not going to
874
00:48:20.050 --> 00:48:23.969
name any companies, but I remember years ago, I was
875
00:48:24.150 --> 00:48:27.130
at a big March event. In a foreign country. And
876
00:48:27.150 --> 00:48:32.170
I was told by somebody, we live off of individuals
877
00:48:32.570 --> 00:48:37.269
that take Tylenol and ibuprofen. Oh, man. And it's because
878
00:48:37.329 --> 00:48:41.980
it wrecks your kidneys and your organs. Sunlight. Phenomenal for you.
879
00:48:42.820 --> 00:48:45.099
Phenomenal for you. One of the best things you can take,
880
00:48:45.179 --> 00:48:48.699
you just have to watch in moderation, especially as you age.
881
00:48:48.840 --> 00:48:51.599
You really have to be cautious with that aspect of it.
882
00:48:52.039 --> 00:48:55.880
But sunlight, there is nothing more important than specific UVs
883
00:48:56.440 --> 00:48:59.070
and the ones in the morning, regardless of it not
884
00:48:59.119 --> 00:49:03.090
being sunny out, get out there during daybreak. It's the
885
00:49:03.190 --> 00:49:07.289
best form of energy you can actually get. Daily walking. Oh, it's,
886
00:49:08.050 --> 00:49:09.250
there is nothing better than walking.
887
00:49:09.269 --> 00:49:10.090
I agree.
888
00:49:10.409 --> 00:49:12.630
Period. There is nothing better. Before, like, you'd get, you know,
889
00:49:12.650 --> 00:49:14.769
you'd get back surgery, you'd have whatever. Oh, no, you
890
00:49:14.789 --> 00:49:16.170
got to be, you got to lay down for a while.
891
00:49:16.489 --> 00:49:18.550
Now it's the complete opposite. It heals you so much quicker.
892
00:49:19.130 --> 00:49:21.550
Get out there and walk. If you have pain, it
893
00:49:21.570 --> 00:49:23.570
increases blood flow. It helps healing.
894
00:49:24.340 --> 00:49:24.679
Walk.
895
00:49:25.019 --> 00:49:26.340
Walking is the best thing you can do.
896
00:49:26.699 --> 00:49:28.679
I walk a lot, but, you know, it's four or
897
00:49:28.719 --> 00:49:30.260
five miles a day. I don't say everybody has to
898
00:49:30.300 --> 00:49:32.079
do that. But when I made that change, because in
899
00:49:32.139 --> 00:49:33.960
my head, I was always like, oh, I got to
900
00:49:33.980 --> 00:49:37.000
do all this hardcore, you know, run, run and all
901
00:49:37.019 --> 00:49:40.280
of this. Dude, it's changed my life. I mean, really,
902
00:49:40.480 --> 00:49:43.780
it really, really has. And multitude of reasons why not.
903
00:49:43.800 --> 00:49:46.519
And the movement and everything is one, but the ability
904
00:49:46.579 --> 00:49:49.920
for me to then really relate with the surroundings and
905
00:49:49.940 --> 00:49:52.659
the earth, I spend it, you know, prayer time doing
906
00:49:52.679 --> 00:49:53.239
that or whatever.
907
00:49:53.280 --> 00:49:55.679
And that's not for everybody. Fine. But that for me, it's,
908
00:49:56.039 --> 00:49:59.139
it's a, like a decompression from everything that's around me.
909
00:49:59.659 --> 00:50:02.300
So it's soothing to the soul on top of the, that,
910
00:50:02.360 --> 00:50:04.539
that makes two of us. I was in the military.
911
00:50:04.559 --> 00:50:07.679
I would run, I was a combat engineer, demolition specialist
912
00:50:07.719 --> 00:50:11.789
in the army. I would run six to 15 miles.
913
00:50:11.849 --> 00:50:14.630
It just range to a day. Yeah. When I left
914
00:50:14.670 --> 00:50:17.809
the military, I still ran, ran, ran at some juncture.
915
00:50:18.389 --> 00:50:21.519
You have to stop because it breaks down the joints.
916
00:50:22.059 --> 00:50:24.360
The switch is exactly what you said. For instance, I
917
00:50:24.420 --> 00:50:26.579
have a wonderful, I love the hell out of my dog.
918
00:50:26.599 --> 00:50:30.639
I have a great Doberman. They're crazy, active dogs. He
919
00:50:30.719 --> 00:50:32.860
forces me every morning to get out there. I live
920
00:50:32.880 --> 00:50:35.780
in the Hills where, you know, walking, running on a
921
00:50:35.820 --> 00:50:39.050
daily basis, hiking through the Hills. It completely, it's the
922
00:50:39.239 --> 00:50:41.840
best way to start off your day. Clears your mind,
923
00:50:42.340 --> 00:50:46.679
you know, get that fresh air, get that atmosphere, look
924
00:50:46.739 --> 00:50:50.559
up in the sky, you're alive, touch the ground, get
925
00:50:50.599 --> 00:50:52.800
the grounding aspect of it. The best way to start
926
00:50:52.840 --> 00:50:55.019
off your day. I talk to my mom all the time.
927
00:50:55.539 --> 00:50:57.960
Like I tell her, mom, did you go outside today?
928
00:50:58.820 --> 00:51:01.260
Did you do some breathing exercises? It's going to shift
929
00:51:01.280 --> 00:51:03.260
your complete mindset and you're going to feel so much better.
930
00:51:03.280 --> 00:51:05.860
I have a big smile because I love animals so much.
931
00:51:05.900 --> 00:51:11.010
That's why I have the huge smile. Last one. There's
932
00:51:11.050 --> 00:51:14.550
nothing more important than being grateful. I mean, and our
933
00:51:14.570 --> 00:51:16.650
common friend, I love when he came up with the,
934
00:51:16.969 --> 00:51:18.269
and it's funny because people don't know what the hell
935
00:51:18.289 --> 00:51:19.949
vitamin G is. You know what's funny?
936
00:51:20.469 --> 00:51:22.980
I was moderating a panel at Biohackers World and I
937
00:51:23.019 --> 00:51:25.079
told them, I said, you know, you've given me this,
938
00:51:25.139 --> 00:51:27.760
now I'm stealing. I gave a speech on vitamin G
939
00:51:27.800 --> 00:51:30.539
and the importance of gratitude because it was a panel
940
00:51:30.579 --> 00:51:33.659
discussing what can you do every day that's like not
941
00:51:33.679 --> 00:51:35.429
supposed to cost you a bunch of money or something
942
00:51:35.449 --> 00:51:37.409
that's easy to implement that you're not doing.
943
00:51:37.429 --> 00:51:42.500
And to me, that is number one. It's number one. Yeah. So, okay.
944
00:51:42.840 --> 00:51:45.900
I know we're winding down. Can you give me a
945
00:51:45.940 --> 00:51:48.179
little insight? Because you kind of teased a little bit
946
00:51:48.219 --> 00:51:50.360
before we started talking about some new studies that you
947
00:51:50.400 --> 00:51:51.059
were working on.
948
00:51:51.079 --> 00:51:56.179
Yeah. So we're a company that's focused on regenerative medicine,
949
00:51:56.199 --> 00:51:58.929
cell therapies. We have multiple clinical studies in autoimmune diseases.
950
00:51:59.969 --> 00:52:03.150
And we're now working with the signaling cues of the
951
00:52:03.210 --> 00:52:06.550
different cells, which we have a phenomenal topical that works
952
00:52:06.989 --> 00:52:10.800
in cosmetics. works phenomenal in orthopedics that we're actually going
953
00:52:10.840 --> 00:52:15.000
into clinical studies on too. But we are now working
954
00:52:15.400 --> 00:52:18.519
on the next level, like these natural killer cells that
955
00:52:18.539 --> 00:52:21.719
we briefly mentioned. We're producing the signaling cues from them
956
00:52:21.940 --> 00:52:24.539
and we're seeing some exciting news in the context of,
957
00:52:24.559 --> 00:52:27.059
because it'll make it a lot more affordable for everybody
958
00:52:27.079 --> 00:52:30.239
in the context of senescence. So we're seeing some really,
959
00:52:30.300 --> 00:52:35.119
really exciting news with that, including seeing, for instance, which
960
00:52:35.159 --> 00:52:37.030
would be a game changer. We talked a little bit
961
00:52:37.050 --> 00:52:39.719
about going out in the sun, if you're exposed too much,
962
00:52:39.739 --> 00:52:42.400
that you can possibly get a melanoma is we're seeing
963
00:52:42.500 --> 00:52:46.400
some of these guidance cues wiping out melanoma. And it
964
00:52:46.440 --> 00:52:49.440
would just be as simple as the context is putting
965
00:52:49.460 --> 00:52:52.460
this stuff on skin, getting melanoma and the skin has
966
00:52:52.500 --> 00:52:53.510
to regenerate on its own.
967
00:52:54.030 --> 00:52:54.530
Wow.
968
00:52:54.719 --> 00:52:57.090
Versus getting somebody to carve, which is what they do.
969
00:52:57.429 --> 00:52:59.449
They're removing chunks of your skin out when you have this.
970
00:53:00.150 --> 00:53:02.869
So we have some pretty exciting stuff that we're, you know,
971
00:53:02.889 --> 00:53:05.250
we've been testing and looking at, and it's, it seems
972
00:53:05.269 --> 00:53:07.849
heading in the right direction. How long do you think
973
00:53:07.889 --> 00:53:10.489
something like that to be available? Quite a while or?
974
00:53:10.690 --> 00:53:12.789
Quite a while. Really? Quite a while. But we, our
975
00:53:12.829 --> 00:53:18.179
cell therapeutics, our study that's furthest along, we're hoping with
976
00:53:18.380 --> 00:53:20.639
good results, because we're in what's called the phase two,
977
00:53:20.659 --> 00:53:23.579
three clinical study transition study is within the next couple
978
00:53:23.599 --> 00:53:26.340
of years, we might have an approval. Really? Yeah. So
979
00:53:26.360 --> 00:53:29.739
you've got optimism, man, at least. Yes, we are because
980
00:53:29.760 --> 00:53:33.329
we're seeing a phenomenal safety profile. no adverse events, which
981
00:53:33.389 --> 00:53:36.989
is fantastic, which is rare. And we're seeing some really
982
00:53:37.070 --> 00:53:40.659
good clinical benefit where I found an angel many, many
983
00:53:40.699 --> 00:53:43.920
years ago that helped fund this entire study. She suffered
984
00:53:43.940 --> 00:53:47.239
from the disease. She's actually seen at Brigham and Women's
985
00:53:47.460 --> 00:53:50.940
Hospital in Boston. And she's in remission of disease now
986
00:53:51.000 --> 00:53:53.429
for four years, which she was in bad shape when
987
00:53:53.469 --> 00:53:56.389
I first met her. Off of all her meds, immunosuppressants,
988
00:53:56.610 --> 00:54:00.070
all of that with this particular type of autoimmune disease.
989
00:54:00.929 --> 00:54:03.940
So it's We're getting some promising things in the context
990
00:54:03.960 --> 00:54:06.460
of cell therapeutics. I love it. I love to hear it.
991
00:54:07.090 --> 00:54:09.929
Before we stop, I want to ask and I want
992
00:54:09.949 --> 00:54:14.579
to do immune system first, cellular health second. So and
993
00:54:14.619 --> 00:54:16.460
I want to preface this because we always have to
994
00:54:16.519 --> 00:54:20.539
be careful. Supplements are good. Supplements, meaning they're used to
995
00:54:20.639 --> 00:54:23.679
supplement what we discussed. The things that we discussed first
996
00:54:23.739 --> 00:54:25.880
are the most important, but let's look at this from
997
00:54:25.920 --> 00:54:30.110
a secondary perspective as the enhancement. What type of supplements
998
00:54:30.170 --> 00:54:32.670
would you recommend someone to look at that would maybe
999
00:54:32.730 --> 00:54:36.010
be staples for you for boosting the immune system?
1000
00:54:36.329 --> 00:54:41.110
Anacetylcysteine. I think it's beyond important because it helps clear
1001
00:54:41.920 --> 00:54:44.860
oxidative stress. Okay, good. I take that. Okay. I take
1002
00:54:44.900 --> 00:54:47.599
that too. Yes. It's one of the biggest important ones.
1003
00:54:48.010 --> 00:54:50.449
It's crazy because you OD on what we just talked about,
1004
00:54:50.489 --> 00:54:52.889
Tylenol or Ibuprofen, you go to the hospital, this is
1005
00:54:52.909 --> 00:54:56.719
what they're going to give you. Wow. Okay. To clear it. Sweet.
1006
00:54:56.860 --> 00:55:00.099
That's one of the important ones. Vitamin D is critical.
1007
00:55:00.179 --> 00:55:07.570
I don't care how much time. In combination with K. Yeah. D3, K2. K2. Yeah.
1008
00:55:07.590 --> 00:55:11.210
It's got to be in combination because, and especially good
1009
00:55:11.269 --> 00:55:15.510
for women because it helps sequester hormones. calcium into bone.
1010
00:55:15.690 --> 00:55:18.070
So it's really, really important in that combination, not on
1011
00:55:18.130 --> 00:55:20.929
its own. You got to watch it. Really, really important.
1012
00:55:21.070 --> 00:55:23.289
I take a particular one that I love and I
1013
00:55:23.349 --> 00:55:25.090
swear by it and I have two of my family
1014
00:55:25.110 --> 00:55:30.340
members on it. And it's, it's designed to help basically
1015
00:55:31.059 --> 00:55:36.139
increase or help the vasculature aspect, you know, of it.
1016
00:55:36.239 --> 00:55:40.619
And it's a particular supplement that it's, um, what was
1017
00:55:40.639 --> 00:55:42.579
the name of it? We talked about this when we
1018
00:55:42.619 --> 00:55:46.289
had a call. I remember you talking about it. Arterial cell. Yes.
1019
00:55:46.550 --> 00:55:48.449
I still have it up on my computer to order
1020
00:55:48.489 --> 00:55:51.349
and I never did. Arterial cell. You know, my mom
1021
00:55:51.369 --> 00:55:53.469
started taking it. It helped her blood pressure. I started
1022
00:55:53.489 --> 00:55:55.719
taking it and it helped lower my blood pressure a
1023
00:55:55.719 --> 00:55:57.050
little bit, which my blood pressure was fine, but I
1024
00:55:57.099 --> 00:55:59.320
helped lower it a little bit more. My sister's now
1025
00:55:59.440 --> 00:56:01.320
on it. She's getting the same exact thing from it.
1026
00:56:01.619 --> 00:56:04.780
Several of my colleagues. And it helps with the vasculature,
1027
00:56:04.820 --> 00:56:07.860
the lining help control all the aspects of it. It
1028
00:56:07.900 --> 00:56:11.190
works really well. It's another one that works well. Another
1029
00:56:11.230 --> 00:56:15.159
big one that I think is really important I would
1030
00:56:15.199 --> 00:56:17.860
have to say is, you know, some people are naysayers.
1031
00:56:18.019 --> 00:56:20.219
I like vitamin C because I don't think you get
1032
00:56:20.280 --> 00:56:21.760
enough of it. If you can get it naturally, then
1033
00:56:21.800 --> 00:56:24.210
it's way better. Yeah. Go with that type of approach.
1034
00:56:24.429 --> 00:56:26.750
It's really good for you. What are other ones I take?
1035
00:56:27.130 --> 00:56:29.130
Some people don't like it, but if you can get
1036
00:56:29.170 --> 00:56:32.630
a good omega-3, I'm all about taking omegas. You have
1037
00:56:32.650 --> 00:56:35.420
to be careful. A lot of them are rancid. Yeah.
1038
00:56:36.050 --> 00:56:38.320
I'm really a SEPA dude, so I have it covered
1039
00:56:38.380 --> 00:56:40.079
on my end. Yeah, so you got it.
1040
00:56:40.079 --> 00:56:42.800
Yeah, correct. I'm a big taker. I take them too.
1041
00:56:43.019 --> 00:56:45.400
I use a specific brand that I like that I
1042
00:56:45.440 --> 00:56:47.400
know is not rancid. It doesn't cause any gut issues.
1043
00:56:48.000 --> 00:56:49.800
If you're taking something and you're burping it up, you
1044
00:56:49.820 --> 00:56:52.670
shouldn't be taking it. No, no. You shouldn't be taking it.
1045
00:56:52.800 --> 00:56:55.449
And then what are some of the other ones that...
1046
00:56:55.409 --> 00:56:57.510
Anything cellular-wise that you recommend?
1047
00:56:57.949 --> 00:57:00.670
Like I brought up urolithin A or senolytics or anything
1048
00:57:00.690 --> 00:57:02.250
like that or anything that you recommend.
1049
00:57:02.690 --> 00:57:05.300
I just go with food. with that for me. I
1050
00:57:05.340 --> 00:57:08.500
go with food, with anything like that. I think important
1051
00:57:08.559 --> 00:57:12.139
foods that you want to take for immune function, you know,
1052
00:57:12.179 --> 00:57:14.119
one of the good ones is actually great is colostrum
1053
00:57:14.280 --> 00:57:16.889
and not enough people take it or do anything with it.
1054
00:57:16.889 --> 00:57:19.150
I'm glad you brought that up. It helps increase natural
1055
00:57:19.170 --> 00:57:22.690
killer cell activity. That's proven. Like we said, we talked
1056
00:57:22.710 --> 00:57:26.309
about yogurts. Anything that deals with helping the gut And
1057
00:57:26.369 --> 00:57:29.739
absorption is key. I eat a shitload of Greek yogurt,
1058
00:57:29.780 --> 00:57:31.760
so that's a good thing. So do I now. I
1059
00:57:31.780 --> 00:57:33.159
do too a lot. Full fat.
1060
00:57:33.219 --> 00:57:35.860
You know how many years I ate low-fat Greek yogurt
1061
00:57:35.900 --> 00:57:38.219
and just ruined it? And not only does it taste
1062
00:57:38.260 --> 00:57:40.760
like shit, but it's stripped of everything that you need.
1063
00:57:40.780 --> 00:57:41.239
You need, yeah.
1064
00:57:41.530 --> 00:57:41.800
Yeah.
1065
00:57:42.260 --> 00:57:43.670
No, I love that.
1066
00:57:43.789 --> 00:57:46.349
And it seems like that pops up in everything and
1067
00:57:46.429 --> 00:57:49.650
everybody I ever talk to that comes on here. Yogurt's
1068
00:57:49.710 --> 00:57:52.349
brought up every rip when I talk about something that
1069
00:57:52.389 --> 00:57:53.170
we're eating for health.
1070
00:57:53.429 --> 00:57:56.570
Yep. In some way, especially when it relates to the gut. Yep. Yeah.
1071
00:57:56.670 --> 00:57:58.889
It works fantastic. I love it. That was good. It
1072
00:57:58.929 --> 00:58:00.650
makes you feel good. It's a great way to start.
1073
00:58:01.210 --> 00:58:02.570
It's a great way actually to start your day and
1074
00:58:02.610 --> 00:58:04.690
end your day. If you want something, you know what,
1075
00:58:04.730 --> 00:58:07.699
if you, if you want your something sweet, throw some
1076
00:58:07.739 --> 00:58:09.579
berries in it and have it at night. Like whatever,
1077
00:58:09.599 --> 00:58:12.340
if you have that sweet craving, you know, throw some
1078
00:58:12.360 --> 00:58:13.610
berries in it and go for it.
1079
00:58:14.019 --> 00:58:16.159
You know why I'm laughing? Cause you know what I
1080
00:58:16.199 --> 00:58:18.480
do every day when I stopped eating at night, first
1081
00:58:18.500 --> 00:58:20.019
thing in the morning before I go for a walk,
1082
00:58:20.039 --> 00:58:22.489
cause I don't eat breakfast. I have a, like a
1083
00:58:22.610 --> 00:58:24.929
half a serving of Greek yogurt and it has some
1084
00:58:24.989 --> 00:58:27.170
blueberries in it with a little protein powder. And that's
1085
00:58:27.230 --> 00:58:28.730
the last thing I have before I go to bed.
1086
00:58:29.050 --> 00:58:31.389
Yep. Every night. And you'll sleep better too. I do.
1087
00:58:32.110 --> 00:58:33.769
Because you've got some carbs in there that help you
1088
00:58:33.789 --> 00:58:34.710
sleep better.
1089
00:58:34.750 --> 00:58:35.210
Yep. Yep.
1090
00:58:35.409 --> 00:58:37.480
That's awesome. I love it.
1091
00:58:37.989 --> 00:58:41.050
Well, it's a personal invite to come back because we
1092
00:58:41.070 --> 00:58:43.449
didn't get through a fraction of what I wanted, but
1093
00:58:43.670 --> 00:58:46.349
when they're this good, you don't. the invite is there.
1094
00:58:46.409 --> 00:58:47.969
I hope you'll come back. Absolutely.
1095
00:58:48.590 --> 00:58:49.409
Come back out this way.
1096
00:58:49.809 --> 00:58:51.860
I knew, and I told you this before we started,
1097
00:58:51.920 --> 00:58:53.920
I was really excited to talk to you. And I
1098
00:58:53.980 --> 00:58:55.780
said that in the car right here, my wife can
1099
00:58:55.820 --> 00:58:57.699
attest to that. And this was even better than I
1100
00:58:57.760 --> 00:58:58.579
expected it to be.
1101
00:58:58.980 --> 00:59:01.659
Awesome. Thank you. Pleasure and honor to be here and
1102
00:59:02.139 --> 00:59:05.710
grateful to actually be here because you have to be grateful.
1103
00:59:05.789 --> 00:59:08.619
People do not understand when you're driving down the street
1104
00:59:09.119 --> 00:59:11.320
and you think you have it bad, look at somebody
1105
00:59:11.440 --> 00:59:15.099
else and see how bad they might have it. Understand.
1106
00:59:15.139 --> 00:59:18.659
I tell my kids on a daily basis, stay blessed,
1107
00:59:19.099 --> 00:59:21.320
be blessed. And if you think things are bad for you,
1108
00:59:22.320 --> 00:59:26.389
look around you and be grateful for what you have to,
1109
00:59:26.809 --> 00:59:29.610
you have to have that, that mindset. I want to
1110
00:59:29.630 --> 00:59:30.730
say this in closing.
1111
00:59:30.909 --> 00:59:33.889
And I say this, I have come to the practice
1112
00:59:34.150 --> 00:59:37.039
to thank God when I leave the gym, because it's a,
1113
00:59:37.510 --> 00:59:38.969
it's a grace to be able to work out and
1114
00:59:38.989 --> 00:59:40.750
do what I love to do, or to sometimes when
1115
00:59:40.769 --> 00:59:42.550
I just leave the store or something, because I was
1116
00:59:42.570 --> 00:59:44.760
able to buy the stuff that we needed and the
1117
00:59:44.840 --> 00:59:46.929
things that you take for granted every single day that
1118
00:59:46.969 --> 00:59:50.199
you don't realize until you get sick or something that
1119
00:59:50.260 --> 00:59:52.500
comes up and you can't go do it, how it
1120
00:59:52.559 --> 00:59:55.110
sucks so bad without it. You should be thankful for
1121
00:59:55.130 --> 00:59:58.090
the littlest of smallest things because those accumulate into what
1122
00:59:58.110 --> 00:59:59.869
you do every single day into your whole life. And
1123
00:59:59.909 --> 01:00:01.849
if you can't be grateful for the little things, then
1124
01:00:01.869 --> 01:00:03.010
you just don't deserve anything.
1125
01:00:03.030 --> 01:00:06.420
Yeah, I agree. You just don't. So thank you, Dr. Pompa,
1126
01:00:06.440 --> 01:00:08.480
for the introduction. Thanks to my doctor.
1127
01:00:09.300 --> 01:00:11.440
Tell everybody where to follow you, where to find you
1128
01:00:11.559 --> 01:00:13.460
and link it all in the description.
1129
01:00:13.880 --> 01:00:16.059
I mean, you can check me out on my Instagram,
1130
01:00:16.099 --> 01:00:20.880
which is DrGonzalezPhD, Restem.com. You can actually have a look
1131
01:00:20.940 --> 01:00:24.650
at us and then also ReHealth.com. is one of our
1132
01:00:24.769 --> 01:00:27.010
ex-US entities. Excellent.
1133
01:00:27.090 --> 01:00:29.789
Like I said, this was freaking awesome. And I really
1134
01:00:29.829 --> 01:00:32.789
enjoyed this to the highest extent. So thanks for coming.
1135
01:00:33.550 --> 01:00:35.860
And that wraps up another one, everybody. I hope that
1136
01:00:35.889 --> 01:00:37.860
you take a ton from this. We're going to come
1137
01:00:37.900 --> 01:00:40.559
back for another part two and maybe part three, who knows?
1138
01:00:40.679 --> 01:00:43.500
So that being said, stay tuned for plenty more to come.
1139
01:00:43.760 --> 01:00:45.639
Dylan Gemelli, signing off.
1
00:00:01.199 --> 00:00:19.399
Bye. Your biology may not be the same in your
2
00:00:19.890 --> 00:00:22.210
40s as it was in your 20s, but your standards
3
00:00:22.250 --> 00:00:24.589
and goals can be even bigger. We're at a time
4
00:00:24.629 --> 00:00:26.989
where we have more tools and methods to not just
5
00:00:27.089 --> 00:00:30.589
live longer, but also healthier with better results as we age.
6
00:00:30.769 --> 00:00:33.670
Aging is no longer viewed as a decline. It's about
7
00:00:33.929 --> 00:00:37.880
optimization and time efficiency. Training smarter and more efficient is
8
00:00:37.909 --> 00:00:40.060
a new standard, and we now know how to get
9
00:00:40.140 --> 00:00:42.640
more from the workouts we are already doing. Now, chances
10
00:00:42.700 --> 00:00:46.079
are your supplement stack is missing a much healthier foundation.
11
00:00:46.179 --> 00:00:50.200
So enhance it with MitoPure, a targeted supplement that revitalizes
12
00:00:50.240 --> 00:00:54.539
your mitochondria, the powerhouse of your cells. Mitochondria are crucial
13
00:00:54.600 --> 00:00:58.700
to overall health, not just energy production. Protein builds muscle.
14
00:00:58.799 --> 00:01:02.920
Creatine supports power. MitoPure helps support the cellular engines that
15
00:01:03.000 --> 00:01:06.640
power both. When your cells thrive, everything follows. So claim
16
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your free aging muscle protocol guide and free sample of
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00:01:10.750 --> 00:01:15.030
might appear gummies from timeline at timeline.com slash Dylan. It's
18
00:01:15.090 --> 00:01:18.280
the science back breakdown of exactly what's happening to your
19
00:01:18.319 --> 00:01:21.819
muscles as you age and how to fight back. All right, everybody,
20
00:01:21.859 --> 00:01:24.780
welcome back to the Dylan Gemelli podcast. So, you know,
21
00:01:25.000 --> 00:01:27.969
one of the huge benefits that you get when you
22
00:01:28.010 --> 00:01:30.849
interview so many different people is that you get introductions
23
00:01:30.870 --> 00:01:34.870
you really weren't ready for, weren't aware were coming. And
24
00:01:34.930 --> 00:01:37.370
that's what happened with me and my guest today. I
25
00:01:37.950 --> 00:01:41.480
did several interviews there back and forth with Dr. Daniel Pompa,
26
00:01:41.519 --> 00:01:44.290
and he said, well, I got a couple people I
27
00:01:44.310 --> 00:01:46.370
think are going to be of significant interest to you.
28
00:01:46.430 --> 00:01:49.349
And I, of course, I'm going to take his his recommendations.
29
00:01:49.450 --> 00:01:52.689
But this one in particular stood out to me of
30
00:01:52.790 --> 00:01:54.849
the ones that he sent me. And I have been
31
00:01:54.890 --> 00:01:57.349
excited for this interview ever since we talked. And I
32
00:01:57.530 --> 00:02:00.189
think that you're going to see very quickly as to why. Now,
33
00:02:00.230 --> 00:02:03.159
my guest today serves as the chief development and science
34
00:02:03.239 --> 00:02:06.760
officer for Restem Group. And he has extensive knowledge in
35
00:02:06.900 --> 00:02:11.099
all aspects of cellular biology, regenerative medicine, biology. and the
36
00:02:11.139 --> 00:02:14.740
key to longevity, maintaining immune health. And he has several
37
00:02:14.800 --> 00:02:17.810
patents and leads multiple clinical studies, which we're going to
38
00:02:17.870 --> 00:02:20.090
talk about today because he's got some new information that
39
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he wants to provide that I can't wait to hear about.
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And I specifically didn't have him tell me so I
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could learn right with you guys in the brand new.
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But he developed an immune-based therapy using natural killer cells
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in the context of longevity. And it demonstrated one of
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the first of its kind methods to reduce immunity immunosenescence
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in humans. And he's also produced a regenerative medicine exosome
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topical that's disrupted the cosmetic rejuvenation space. So we're going
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to get into all this and plenty more. My friends,
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welcome Dr. Rafael Gonzalez. Dylan, thank you for having me here.
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Pleasure to be here and love to educate as you do.
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It's a lot of fun to do, especially when we
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talk about the most important thing in our body, the
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immune system.
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I am so stoked. You know, I've actually had some
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pretty strong discussions.
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Dr.
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Jeffrey Bland and I had a really good one on
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the immune system, Dr. William Lee, all highlighting the importance
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of it. And I know that you have an extreme
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expertise in that. And so my knowledge base is bigger
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than when you and I talked, and I'm ready for
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you to enhance it to the highest extent amongst everything
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else that you talk about. So once again, thanks for
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coming in here to see me. I really value anybody's time,
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especially yours, because I know the extent of where we're
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going today. So let's lead into that with some of
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the discussion on the immune system. But you made it
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very clear in what you just said, the most important.
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Why do you say that? The main reason is because
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every single disease has an immune component to it. Believe
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it or not, and some people say out there, well, no,
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if I have a genetic disease, it does not. No,
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there's an immune component. to the progression of that disease.
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Always is. For a simple example of such is something
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such as pediatric Duchenne muscular dystrophy, which is a devastating
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thing for pediatric kids. It's awful. Yet, if I can
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help control some of the immune destruction in there, I
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can slow down the progression of that disease. That's why
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the immune system is so powerful. There's every single disease.
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Neurological diseases, we take them for granted. It's mostly an
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immune system issue. The immune system has gone awry. It's
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not doing what it's supposed to do. And it causes
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a neurological issue. Would you say that progressively over time
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that immune system health has declined? Significantly. Okay. And why
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would that be? One of the biggest burdens is a
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lot of things. Number one is diet, what's going on,
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what we're being fed, what we're being dealt with on
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a daily basis. Two, the environment is really, really bad.
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And three, your immune system, as you age, every cell
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in your body ages, no matter however you think about it.
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It's something called the Hayflick limit. Every cell in your
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body has a finite amount of divisions, and at some juncture,
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it stops dividing and doesn't do much. This is the
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Hayflick limit. But the biggest problem as you age, and
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you can see this as you're developing is on a
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daily basis, your immune system is challenged. Well, what happened
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six years ago? Six was a six, seven. It's been
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a long time now. Six years ago, COVID.
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Right.
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We got hit with another challenge to our immune system. Yes. Yes.
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And it was a devastating challenge to the immune system.
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And the simple analogy that I talk about a lot
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of times is, listen, the UFC fighter is going to
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beat a standard two, three, four people on the street.
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But when seven, eight, ten people come at him, he's
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not going to win. And it's what happens on a
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regular basis with your immune system. It's really bad because
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you're challenged with daily bacteria. You're challenged with daily mold, toxins, fungus, microplastics,
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which is a nightmare, metals, which are a nightmare, the environment,
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the pollutants, everything. Your immune system has to deal with that.
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And if your immune system gets overwhelmed, it's a big problem.
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The biggest issue we're having is, we go back to
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the COVID, is the virus. And a lot of people
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don't understand. They think a bug is a bug is
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a bug. No. A virus is something that requires a host.
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You are the host while this alien has come into
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you And it's crazy, if you look at images of it,
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it looks like a little spaceship that basically shoots its
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DNA into your cells and then replicates and it lives there.
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So this thing knows ways of, since you're required for
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it to live, it knows ways how to hide and
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how to cause havoc. And if your immune system is
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challenged or you're dealing with, eight, 10 other things, this
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thing is going to be a massive burden. Like there's
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many diseases now and there's more and more evidence coming out,
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especially autoimmune diseases, which are becoming really problematic, not only
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in the US, but worldwide. More and more of them
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are surfacing. More individuals that think they only have rheumatoid
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arthritis have an ankylosis spondylitis, have ulcerative colitis, have all
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these different autoimmune diseases sort of combined in one. It's
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because the immune system has become somewhat hijacked in many instances.
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And the hijacking many times are these viruses, where we
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finally identified at least one so far that is multiple
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sclerosis that is hijacked by Epstein-Barr virus is what causes it.
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So these viruses are what's causing a lot of problems.
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Don't get me wrong. There are good viruses, like there's
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good bacteria that we have to live symbiotically with. But
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the majority of them, specific ones, are really, really bad
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and detrimental to our system.
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What's the direct cause to your cells that then in
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turn weakens the immune system?
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What ends up happening is the immune system, especially in
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the context of an autoimmune disease, it becomes exhausted. You know,
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cells divide and turn over on a regular basis.
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Right.
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Your body, especially when you have an autoimmune disease, your
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body has now saw something as it is foreign. So
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if it sees something as foreign, it goes on to
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overdrive to attack that foreign entity. For instance, in a
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particular disease that we have a clinical study for, it's
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called polymyositis dermatomyositis, myo meaning muscle, muscle, it attacks muscle,
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it attacks skin. Eventually these patients will have issues with
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their lungs because it'll start wiping out lung tissue also.
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which they end up succumbing to the lung portion of
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it because of it. And it sees your own skin,
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your own muscle as foreign. It's killing it. And it's
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on overdrive. It's not balanced. It's not in what's called
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a regulatory state, which is the way your immune system
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is supposed to be. Our body's supposedly consistently in a
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regulated state, which is called homeostasis. And we want to
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be in homeostasis. When the immune system is consistently on
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overdrive and cells are dividing, at some juncture, we talked
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about the first thing we talked about earlier, that hayflake limit,
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the cells are no longer going to be able to
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function correctly. and then the system says well wait a
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second how do i because your immune systems works in
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one particular way it is attack try to remove try
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to eliminate which is inflammation and then to the opposite spectrum,
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which is called a TH1 inflammatory response. And then to
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the opposite spectrum, it has to heal, which is a
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TH2 anti-inflammatory response. But if you have too much of this,
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which is that inflammatory response, this healing cannot respond. It
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can't do anything. The weird thing about the immune system
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is cancer. I was going to ask about that, but
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I'll let you go first. Is cancer. That cancer patient,
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completely opposite from that autoimmune patient, does not mount a
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killing response. That individual that has cancer, we now know,
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has a high amount of regulation, so there's no killing.
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That's one aspect of it, besides the cancer's ability to hide. Right.
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It finds a way to hide, to get away from anything,
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and to do it. but you don't have an appropriate
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mounting killing response. In those patients, you normally have a
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healing response, but you can't heal anything without eliminating it.
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Could you just explain what causes cancer to start like cellularly,
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how it actually begins? There's many, well, there's many different
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things that happen, mostly mutations. So if you think of
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on a daily basis, you go outside, and you're exposed
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to UV light, and you most likely will get a
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mutation in your skin. Your immune system, the first responder
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to that, believe it or not, one of the first
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responders is called the natural killer cell. It is supposed
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to target, it is supposed to eliminate that immediately. That's
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when your immune system's optimized. If it is not, then
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this thing goes unchecked. That unchecked has a possibility, just
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in the context of let's say skin, to go into
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the blood system. What people don't understand is that we're
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not quite there in the technology of the testing aspect.
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Somebody will go and they'll go get a full body scan.
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My body scan is completely clear. The problem is to
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you identify a million cells in a ball and being
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a cell biologist, I see this is a speck on
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a table. There is no technology out there that's really
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going to identify that speck on the table. We have
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to talk about a billion cells in a ball, which
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is the end of my fingertip, which is not much.
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That's a problem. That's something that might be identifiable. But
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even that's a little bit difficult to identify. Because when
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you talk about people have, you know, a millimeter, you know,
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that's what they normally catch is a millimeter, two millimeters,
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a centimeter. You know, a centimeter is billions of cells
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in a ball. It's massive. I know. And then what
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people don't know, the other thing that we don't understand,
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which now they're starting to get a little bit more
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progressive on the testing aspect of it, is looking at
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those cells that are in, like you find in a
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lesion or something like that, those cells that are found
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have the propensity to release cells. And these are called
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circulating tumor cells. And those cells, there's some testing now
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that you can actually detect those, which people are now
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getting smarter, smarter with detections of it. That is the
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problem when you talk about somebody who's had cancer and
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you talk about more than anything else, no evidence of
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disease versus in remission of disease. You couldn't find disease
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versus in remission of disease because you don't really know.
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And it's hard to detect if this stuff has been
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circulating and if it's going to come big comeback. The
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key to all of this is maintaining immune health. Would
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you say in all your years of, of understanding and observation,
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And I think I know the answer, but I want
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to know from you that a weakened immune system will
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make you more susceptible to developing cancer or cancerous cells.
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A thousand percent. Okay. All right.
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So that's why I wanted you to give the full
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explanation of how it got caused and then relate it
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to the immune system in general.
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Yeah. Something in the body has gone awry and the
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immune system hasn't detected it, hasn't killed it. The immune
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system is not working optimally. So if you were say
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around cancer causing aspects, whether, and people can argue what
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those are anymore, but let's just say you're around heavy,
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heavy chemicals that would potentially cause cancer, microplastics, et cetera.
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If you have a very strong immune system, you have
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a far greater chance of not developing cancer as opposed
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to somebody that's got a weakened one or has kind
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of suffered some sort of some alterations with their immune system.
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A thousand percent.
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Yep.
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Okay. Correct. All right. So it's, It's a cellular problem,
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but the immune system is.
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Going to play a huge role into preventing or at
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least mitigating the potential spread or growth of that.
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Yeah, well, the immune system is the one that's got
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to take care of the immune cells, the immune system
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in general, whether it's part of the innate, the immediate response,
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or the secondary response, which is the military. Those have
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to be able to work together and eliminate and kill, regulate,
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and heal. They are the key to recovery. all aspects
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of longevity, including, believe it or not, your skin, what
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your appearance is, whether you look healthy, you're not healthy,
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and it's an issue. And one of the things he
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has talked about, for instance, if you get burdened with
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massive metal toxicity, what does the immune system have to do?
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The immune system has to now go and direct it
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towards that. The entire immune system has to go, especially
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when you're older, has to go and direct it towards that.
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It doesn't even mount a correct short response, like when
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you were young. But what happened to everything else that's
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going on in your body, the other viruses and everything else? Now,
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all of these things are opportunistic. That's where these things,
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you know, surface. The simplest example of this is when
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you look at chickenpox, or when you look at basically,
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you know, the age-associated aspects of chickenpox, which is shingles,
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is it's an opportunistic virus. Your immune system becomes weakened,
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or you have Stress, stress is a killer. You get
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stress and the immune system becomes dampened, weakened. This now surfaces.
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Your immune system has to figure out how to remove
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it to clear it.
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When my dad passed away, my mom got shingles and
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she got psoriasis and those are extremely stress related problems.
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And that weakens your immune system and boom.
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Wow. Okay.
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Now. we kind of covered that cellular side of it.
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I want to shift a little bit now. There's a
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couple of things that I want to get into with
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the immune system, but first you brought up diet. And
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so I want to shift to the problems in our
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everyday diet and how that relates to our immune system.
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Certainly the buildup of inflammation is really the center of
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all diseases. And I'm sure that just rashes our immune system,
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but can you, can you correlate that with the foods
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that we're eating and then maybe touch on some of
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the foods that you would say are are beneficial to
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our immune system and then others that are just destroying it.
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The problem with the.
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Food is the gut houses about 60% of the immune system.
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It's a massive immune component. And what people don't understand,
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if you should know this, is when you eat too
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much or when you eat processed stuff or you eat
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bad stuff, why do you feel, number one is, why
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do you feel sick? It's because there's what's called a
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neural gut access. There's an inflammation that happens in the gut,
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and then it sparks your brain to tell you, I'm sick.
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I need to stop eating. That's another aspect of nausea, vomiting.
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It's telling you, your system is telling you to stop eating.
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When you feel nausea or you don't feel well, your
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system is telling you, stop. Or it's telling you, you
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ate something that's bad. It's a big issue because it
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taps the immune system and puts you in an inflamed state.
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Putting you in an inflamed state is basically trying to
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resolve a gut issue when the immune system should be
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dealing with everything else. It should be dealing with pathogens
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in your vasculature, in your blood system, in your tissue.
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It should be dealing with all of the viruses that
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are there, keeping them at bay. It should be regulating
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the entire system, not focused on the gut. And that's
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one of the things I learned was how the immune
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system works. proportionally was so intertwined into the gut because
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I really wasn't aware of that.
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And that's when I've been getting more into the discussion
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of gut, leaky gut. So I've covered the basis on
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00:18:52.000 --> 00:18:55.240
that a lot. But when it comes to learning about
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00:18:55.279 --> 00:18:57.220
how it all ties together, I think that you're going
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to have more expertise than anybody that I've talked to
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about that. And that's why my concern with the diet
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especially is leading to so many other problems because now
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I understand it's the tie into the immune system. And
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if you're making your immune system work one direction, you're
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leaving yourself wide open. It's like you're sending all your
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troops one way and there's no army on the other side.
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So if your diet is really bad and it's causing
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you this slew of problems over here, you get a virus,
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you get a COVID, you get something else. My assumption
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is it's a hundred times worse than what it should
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have been.
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Yep. You're going to feel bad. It's going to take
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00:19:32.970 --> 00:19:35.710
you longer to recover, especially as you age, because the
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immune system is not functioning correctly. And it's going to be,
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you know, a problem. The process, for me personally, the
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00:19:42.109 --> 00:19:46.569
worst thing are the processed breads, carbohydrates. There's probably nothing worse.
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Like here in, at least in the US. I avoid
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bread the only bread I'll eat is like an organic
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sourdough that's the extent of it because I know it
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has you know good bacteria in it it's done well
343
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but other than that I notice when I touch any
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form of bread I don't feel right I feel off
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there's pastas that are similar There's grains and rice that
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are similar. There's even people talking about oatmeal being good.
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00:20:16.359 --> 00:20:20.190
These are oats. Yeah, it's not, you know, all has
348
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cholesterol benefits. These are oats that tap your gut and
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your microbiome significantly. You know, I just, I focus on
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what's called clean, organic eating as much as possible. Eat clean.
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I'm not a pescatarian, vegetarian, vegan, carnivore. It's an individual thing.
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You might suit well with being a vegetarian. I might
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be an omnivore. I'll eat everything and I switch it
354
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up and I change it around. I don't, you know,
355
00:20:51.160 --> 00:20:54.539
I cannot go vegetarian. I don't feel well. I cannot
356
00:20:54.579 --> 00:20:57.579
go carnivore. I do not feel well. If you don't
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feel well, that diet's not for you. You have to
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find that right fix that you feel homeostatic. You feel
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00:21:04.380 --> 00:21:06.519
fine on a daily basis that you're energized and you
360
00:21:06.559 --> 00:21:09.599
feel well. And the other big thing that nobody focuses
361
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on is people eat way too late. Yes.
362
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I used to do it all the time. All the
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00:21:15.269 --> 00:21:18.509
time I did. It's you don't understand you sleep for
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00:21:18.549 --> 00:21:23.609
a reason. You're sleeping to heal. If you're eating, where's
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00:21:23.650 --> 00:21:24.950
all your energy going.
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At nine o'clock at night or eight o'clock at night
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and you went to bed at nine 30 or something
368
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like that, your food is still digesting and your, your
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00:21:31.119 --> 00:21:34.160
body doesn't have that opportunity to heal. You need that
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00:21:34.220 --> 00:21:37.920
opportunity to heal. That's what sleeping is for. It helps
371
00:21:37.960 --> 00:21:41.619
your immune system relax. It helps your gut, your digestive system.
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Your metabolic function, which is so important, has to be
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dimmed down. The other thing is there's only one thing
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that ages you. It's what we just talked about. The
375
00:21:52.609 --> 00:21:55.490
biggest thing is the Hayflick limit. Cells divide, stop dividing.
376
00:21:55.829 --> 00:22:00.190
When you eat excessively, what ends up happening? Your liver
377
00:22:00.230 --> 00:22:04.170
has to process all that. Cells have to divide. Cells
378
00:22:04.210 --> 00:22:08.710
have to work on overdrive. Cells age. You got to
379
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cut it down. You got to eat clean. You got
380
00:22:11.390 --> 00:22:13.690
to cut it down. You know, the focus has always
381
00:22:13.730 --> 00:22:19.150
got to be diet, sleep, exercise. Yes. If you're not moving,
382
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you're going to lose it. And the crazy thing about
383
00:22:21.950 --> 00:22:26.000
it that people don't understand is those are simple. People
384
00:22:26.019 --> 00:22:27.599
talk about, oh, it costs too much money to live
385
00:22:27.640 --> 00:22:29.839
longer to do that. No. Those are three things that
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00:22:29.859 --> 00:22:34.200
you have full control over. There's no excuses. I blew
387
00:22:34.220 --> 00:22:37.680
my knee out. Hey, guess what? I have arms. I
388
00:22:37.720 --> 00:22:40.920
can do a cycle with my arms. I can lift
389
00:22:40.940 --> 00:22:43.500
with my arms. I can do exercise with my arms.
390
00:22:43.940 --> 00:22:46.940
I can do breathing exercises. Those are exercises. I don't
391
00:22:47.000 --> 00:22:49.109
need my knee to do that. Vice versa. I blow
392
00:22:49.150 --> 00:22:51.170
my arm. I mess up my back. I have legs
393
00:22:51.210 --> 00:22:53.809
to walk with. These are simple things that anybody could
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00:22:53.829 --> 00:22:56.470
do on a daily basis. Set a routine of sleeping
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at a certain time. Stop eating at a certain time.
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00:22:59.470 --> 00:23:01.980
You have full control over all that. And that doesn't
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00:23:02.000 --> 00:23:04.500
cost you anything. No, I agree. I don't even want
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00:23:04.539 --> 00:23:05.980
to tell you how I used to eat late at
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00:23:06.019 --> 00:23:07.759
night for so many years. I did the same thing.
400
00:23:07.859 --> 00:23:10.269
It's terrible. It's absolutely terrible. And then you wonder why
401
00:23:10.289 --> 00:23:12.289
you don't sleep well and don't feel well in the morning.
402
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403
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404
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419
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Yeah.
420
00:24:13.839 --> 00:24:15.880
You know, and it's funny, you brought up the oatmeal.
421
00:24:15.900 --> 00:24:18.339
So I was like a 15 year, never missed a
422
00:24:18.380 --> 00:24:21.519
day of oatmeal. And I had several people over years
423
00:24:22.160 --> 00:24:24.180
tell me, you need to cut it out. And you know,
424
00:24:24.539 --> 00:24:26.900
you get used to something and they start believing your
425
00:24:26.940 --> 00:24:29.730
own BS. And I'm a freaking nutritionist. And as soon
426
00:24:29.769 --> 00:24:32.990
as I stopped eating it, man, I feel so much better.
427
00:24:33.009 --> 00:24:37.019
You know, it makes you feel like heavy. And I don't,
428
00:24:37.059 --> 00:24:39.640
like you said, there's a lot of things that you
429
00:24:39.660 --> 00:24:42.440
can do to improve your cholesterol aside from freaking oatmeal,
430
00:24:42.779 --> 00:24:45.759
you know, and you get these people that get so angry.
431
00:24:45.900 --> 00:24:48.599
I told my friend, Ben Azadi, the oatmeal mafia was
432
00:24:48.619 --> 00:24:50.359
going to come for us because they get so pissed
433
00:24:50.839 --> 00:24:52.440
about it. And it's like, and it's the greatest. I love,
434
00:24:52.460 --> 00:24:55.039
you know, he's great. We had a, we had a good, good,
435
00:24:55.119 --> 00:24:58.660
deep conversation that we just studied or sat on oats.
436
00:24:58.700 --> 00:24:59.279
It was great.
437
00:24:59.339 --> 00:25:02.980
Cause it's, It's a polarizing thing like so many other things.
438
00:25:03.039 --> 00:25:06.160
But I'm glad you pointed that out. Could you give
439
00:25:06.200 --> 00:25:09.220
a few foods that you would recommend for improving your
440
00:25:09.259 --> 00:25:12.549
immune system that are, you know, and whatever they are,
441
00:25:12.559 --> 00:25:15.029
it doesn't matter what diet it falls under. It's just
442
00:25:15.089 --> 00:25:19.470
simply these are good foods for your gut or immune system. Yeah, there's,
443
00:25:19.769 --> 00:25:22.089
I mean, there's quite a few of them. You can
444
00:25:22.150 --> 00:25:26.960
discuss some fruit. Things that increase vitamins, like vitamin C,
445
00:25:27.319 --> 00:25:30.640
vitamin D. Depending on if you can tolerate specific types
446
00:25:30.700 --> 00:25:35.230
of dairy, they work well. Things that have, like for instance,
447
00:25:35.349 --> 00:25:39.109
probiotics in them are really phenomenal. You know, like yogurt,
448
00:25:39.150 --> 00:25:41.970
Greek yogurt is phenomenal. High in protein.
449
00:25:42.289 --> 00:25:44.670
You know, people that can tolerate the dairy aspect of
450
00:25:44.750 --> 00:25:48.170
cottage cheese, it's actually another thing that's actually really, really
451
00:25:48.190 --> 00:25:57.450
good for you. Specific fruits, things that have strong antioxidants. pomegranates, blueberries, strawberries, raspberry,
452
00:25:57.869 --> 00:26:00.490
as long as they're organic, because it's crazy. You know,
453
00:26:00.509 --> 00:26:02.490
these things are sprayed very, and they're, and they're all,
454
00:26:02.529 --> 00:26:04.380
they're part of what's called the dirty dozen. You have
455
00:26:04.390 --> 00:26:06.559
to watch those too. But as long as they're organic
456
00:26:06.599 --> 00:26:09.619
and they're clean, lean meats are good. As long as
457
00:26:09.660 --> 00:26:13.279
they're lean, because they provide the basis of proteins, amino acids,
458
00:26:13.339 --> 00:26:17.099
which our body functions on are really good. Specific fishes,
459
00:26:17.579 --> 00:26:19.400
fish you have to be careful with too. Some people
460
00:26:19.420 --> 00:26:21.609
say I stay away from it. busy oceans plagued with
461
00:26:21.670 --> 00:26:24.390
mercury and there's a bunch of other issues, parasites, but
462
00:26:24.589 --> 00:26:26.990
eat clean, organic and read what you're doing. And then
463
00:26:27.049 --> 00:26:29.910
ultimately what it boils down to personally, I think is
464
00:26:30.769 --> 00:26:32.549
how it makes you feel. If you ate something that
465
00:26:32.589 --> 00:26:36.380
you don't, if somebody told you that something is healthy
466
00:26:36.730 --> 00:26:39.200
and then you eat it and you didn't feel well,
467
00:26:39.619 --> 00:26:41.960
then it's not for you. Like for instance, I don't
468
00:26:42.220 --> 00:26:46.450
tolerate almonds. And I noticed, I found out actually later
469
00:26:46.470 --> 00:26:49.039
because I love almonds, that it's actually the skin. So
470
00:26:49.079 --> 00:26:52.460
I can do a Marcona almond perfectly fine. But if
471
00:26:52.500 --> 00:26:55.079
I do the other ones, my gut messes up and
472
00:26:55.099 --> 00:26:58.140
I actually get body aches, which is what's weird too
473
00:26:58.799 --> 00:27:00.849
from it because I don't tolerate it. And there's certain
474
00:27:00.880 --> 00:27:02.789
fishes I know that I can't tolerate either. I don't
475
00:27:02.849 --> 00:27:04.990
eat them. I stay away from them. But, you know,
476
00:27:05.009 --> 00:27:06.789
there's a lot of good eggs are fantastic.
477
00:27:07.089 --> 00:27:07.269
Yeah.
478
00:27:07.329 --> 00:27:09.529
And I love that you said that. And I learned
479
00:27:09.589 --> 00:27:12.299
that with the almonds as well several years ago. But yeah,
480
00:27:12.339 --> 00:27:12.559
I mean.
481
00:27:13.279 --> 00:27:15.400
I was kind of curious too, if, if there was
482
00:27:15.960 --> 00:27:21.160
any like comparison there in terms of is protein better
483
00:27:21.180 --> 00:27:23.400
or fats better or carbs better when it comes to
484
00:27:23.440 --> 00:27:25.579
immune system, or is it just really based on the food?
485
00:27:25.640 --> 00:27:28.740
Not so much the, the macro or micronutrient of it.
486
00:27:29.059 --> 00:27:31.839
You know, what's, what's the funniest thing about it is
487
00:27:32.039 --> 00:27:34.079
you want your immune system to be active, but you
488
00:27:34.119 --> 00:27:37.369
don't want your immune system to be overactive. And this
489
00:27:37.430 --> 00:27:40.210
is sort of, something crazy. So we have, we work
490
00:27:40.230 --> 00:27:43.069
with natural killer cells and we will collect people's blood
491
00:27:43.450 --> 00:27:46.750
to work with it. And the unusual aspect is a
492
00:27:46.769 --> 00:27:49.410
lot of people talk about keto diets and keto diets
493
00:27:49.430 --> 00:27:52.089
are great. Don't get me wrong. But when I get
494
00:27:52.410 --> 00:27:56.329
blood from an individual that's in ketosis, what does ketosis
495
00:27:56.349 --> 00:28:00.150
sort of do? It works great in the context of
496
00:28:00.230 --> 00:28:04.220
maintaining health, but it also puts your system, your immune
497
00:28:04.259 --> 00:28:06.849
system a little bit in a quiescent state. So I
498
00:28:06.930 --> 00:28:11.410
can't grow cells really well. But when I ask somebody,
499
00:28:11.670 --> 00:28:15.390
and we've tested this before, to before I collect your blood,
500
00:28:15.410 --> 00:28:19.109
I need you to do me a favor and have
501
00:28:19.130 --> 00:28:26.039
some yogurt, Greek yogurt, have basically some sourdough toast. Or
502
00:28:26.130 --> 00:28:29.619
bring in some good complex carbohydrates into the picture. Then
503
00:28:29.640 --> 00:28:31.660
I'll grab your blood. Then I have a little bit
504
00:28:31.700 --> 00:28:34.420
more of an active immune system and I can collect better.
505
00:28:35.079 --> 00:28:38.140
So it's something that we've noticed with it. It is
506
00:28:38.220 --> 00:28:44.210
diet specific. Individuals that do too much carnivore in the
507
00:28:44.250 --> 00:28:47.710
context of the immune system too, you have to watch that.
508
00:28:48.269 --> 00:28:51.430
Although it's done one important thing, you will have people
509
00:28:51.450 --> 00:28:55.640
with autoimmune diseases that'll go strictly carnivore. Those people that
510
00:28:55.680 --> 00:29:01.039
go strictly carnivore with autoimmune diseases do really well because
511
00:29:01.079 --> 00:29:04.900
it quiesses the immune system. It's very subjective. That is
512
00:29:04.920 --> 00:29:05.779
a down. Yeah.
513
00:29:05.960 --> 00:29:06.240
Yeah.
514
00:29:06.339 --> 00:29:08.119
But if you want something that's going to make your
515
00:29:08.140 --> 00:29:12.559
immune system more active, you need to introduce complex carbs
516
00:29:12.619 --> 00:29:15.420
and good carbs to it. So going with that, I'm
517
00:29:15.529 --> 00:29:21.089
not specific to any specific type of diet. Like for instance, keto, carnivore,
518
00:29:21.809 --> 00:29:24.029
they're all different and they're dependent on you. I eat
519
00:29:24.329 --> 00:29:27.910
all foods, all different types. I switch it up. I'll
520
00:29:27.950 --> 00:29:30.569
go different depending on, you know, what I want. And
521
00:29:30.609 --> 00:29:36.470
the reason why... I'm not specific on being vegetarian, on ketogenic,
522
00:29:36.670 --> 00:29:39.130
on any of those is because when I looked at
523
00:29:39.190 --> 00:29:42.450
senescence and when I looked at immune function in patients
524
00:29:42.490 --> 00:29:48.549
from blood, I've seen that if I have an individual
525
00:29:48.930 --> 00:29:51.799
that is on ketosis for too long and I pull
526
00:29:51.839 --> 00:29:55.700
his blood, and this makes complete sense, I pull their blood,
527
00:29:56.460 --> 00:30:00.160
their NK cells are not that active. But it's like
528
00:30:00.200 --> 00:30:02.859
that for a reason. And it's like that for a
529
00:30:03.019 --> 00:30:07.740
good reason because the immune system is somewhat quiescent. It's healthy,
530
00:30:07.900 --> 00:30:10.960
but it's quiescent. But when I want to remove and
531
00:30:11.000 --> 00:30:13.920
eliminate senescence, I need something that's a little bit more
532
00:30:14.099 --> 00:30:17.500
active that I can grow. That's why I tell individuals
533
00:30:17.519 --> 00:30:19.480
when we're going to go collect their blood is I
534
00:30:19.519 --> 00:30:22.180
tell them, please do me a favor and eat something
535
00:30:22.240 --> 00:30:25.180
like an organic sourdough bread, which is the only type
536
00:30:25.220 --> 00:30:26.700
of bread that I would eat here in the United
537
00:30:26.740 --> 00:30:30.369
States because the other one's serve, they're bad. They're really
538
00:30:30.410 --> 00:30:32.089
bad for you. A lot of stuff here in the U.S.
539
00:30:32.130 --> 00:30:35.069
is really bad for you. Eat some eggs. Eat some
540
00:30:35.190 --> 00:30:39.349
complex carbohydrates. Ones that are good. Ones that are organic.
541
00:30:39.990 --> 00:30:43.039
Ones that are not bad. I talk about, you know,
542
00:30:43.059 --> 00:30:45.380
the oatmeal's are bad. Stuff like that is people do
543
00:30:45.400 --> 00:30:49.380
not understand. Even, you know, I went to a conference
544
00:30:49.599 --> 00:30:55.099
on autism and pediatric disorders and it's crazy what I
545
00:30:55.140 --> 00:30:59.509
learned there because a lot of people, including me, I
546
00:30:59.589 --> 00:31:05.460
thought that grain rice and all these rices were good. No,
547
00:31:05.500 --> 00:31:08.519
they're loaded with arsenic. I tell you to stay away
548
00:31:08.559 --> 00:31:10.099
from those. The only type of rice you should be
549
00:31:10.180 --> 00:31:13.619
eating for kids that have autism, that have cerebral palsy,
550
00:31:13.640 --> 00:31:19.450
that have all these different issues, are California-grade white rice
551
00:31:19.990 --> 00:31:24.950
or sushi-grade white rice. That's the extent of it. But those,
552
00:31:25.029 --> 00:31:27.980
if you think of the context of longevity, those are
553
00:31:28.000 --> 00:31:31.339
not good for you because... They convert to sugars a
554
00:31:31.380 --> 00:31:33.680
lot too. So that's why we discuss avoiding them as
555
00:31:33.720 --> 00:31:37.109
we age. We discuss avoiding them. But I'm more focused
556
00:31:37.119 --> 00:31:41.630
on eating everything, switching it up. For me personally, I
557
00:31:41.670 --> 00:31:44.910
can't stay on a vegetarian diet. I can't stay on
558
00:31:44.930 --> 00:31:47.250
a carnivore diet. I don't feel well on all of them.
559
00:31:47.410 --> 00:31:51.109
I switch it up. I can't eat almonds. I found
560
00:31:51.170 --> 00:31:53.250
out I can't eat almonds. I removed the skin from them.
561
00:31:53.289 --> 00:31:54.730
I found out after I can eat more corn because
562
00:31:54.769 --> 00:31:57.190
I love almonds. It would cause me pain, cause me
563
00:31:57.210 --> 00:32:00.619
gut issues. So- Some fishes I don't eat. Lean meats
564
00:32:00.680 --> 00:32:03.869
I love. Lean meats, I'll eat them as long as
565
00:32:03.890 --> 00:32:06.809
they're clean, they're good for you. And it's the way
566
00:32:06.849 --> 00:32:08.809
I feel good. And then the big thing is always,
567
00:32:08.849 --> 00:32:11.430
like we talked about earlier, is stop eating at a
568
00:32:11.750 --> 00:32:13.769
certain time frame. Yeah. To go to sleep.
569
00:32:13.930 --> 00:32:16.809
Yeah. Oh, yeah. And I found some blockage in my
570
00:32:16.849 --> 00:32:18.880
heart that I talked to you about on the phone prior,
571
00:32:18.940 --> 00:32:21.539
and I implemented pomegranates. I used to try to help
572
00:32:21.619 --> 00:32:25.900
reverse plaque or at least stabilize and help, but pomegranates also...
573
00:32:26.480 --> 00:32:28.349
And I know this from, like I told you, I
574
00:32:28.390 --> 00:32:30.950
worked with Timeline, which made me study cellular health. But
575
00:32:30.970 --> 00:32:34.779
the pomegranates then relates to urolithin A, which is something
576
00:32:34.799 --> 00:32:37.240
that I use and have come to the understanding of
577
00:32:37.299 --> 00:32:42.039
stimulating mitophagy. So we talked about, you know, different aspects
578
00:32:42.400 --> 00:32:46.509
of cellular health and care. Do you think pomegranates serve
579
00:32:46.529 --> 00:32:49.849
that purpose well too in cellular health? Aside from our
580
00:32:49.869 --> 00:32:52.509
immune system, I'm looking this more on a cellular side.
581
00:32:52.630 --> 00:32:55.730
Is that something that you would recommend for cellular health?
582
00:32:55.730 --> 00:32:57.710
100% because, I mean, I know people that just focus
583
00:32:57.750 --> 00:32:58.829
on pomegranate. Yeah.
584
00:32:59.029 --> 00:33:04.569
Because it's so high in antioxidants. Oxidation is what causes inflammation. Right.
585
00:33:05.049 --> 00:33:07.630
And we all know that. And this is a preemptive
586
00:33:07.990 --> 00:33:12.210
cursor to inflammation is oxidation. The formation of free radicals,
587
00:33:13.470 --> 00:33:17.140
If you reduce them, which is what berries and especially
588
00:33:17.259 --> 00:33:20.960
pomegranate does, you will keep the immune system that it
589
00:33:21.119 --> 00:33:23.000
has an ability to do what it needs to do.
590
00:33:23.420 --> 00:33:23.829
I love it.
591
00:33:24.119 --> 00:33:26.710
Here's the thing, though, that sucks, like you said, is
592
00:33:26.849 --> 00:33:28.890
a lot of these are dirty dozen or they're sprayed
593
00:33:28.950 --> 00:33:31.170
and it's like you're eating these that are supposed to
594
00:33:31.230 --> 00:33:33.549
serve you a purpose and they're actually causing you an
595
00:33:33.650 --> 00:33:36.269
adverse effect if you're not eating the right ones, right?
596
00:33:36.789 --> 00:33:39.369
So we got to be careful on when you and
597
00:33:39.430 --> 00:33:41.650
I say that, and I always preface it just like
598
00:33:41.690 --> 00:33:43.519
you do, make sure they're organic, make sure they're as
599
00:33:43.579 --> 00:33:46.339
clean as you can possibly get, because otherwise you're really
600
00:33:46.519 --> 00:33:49.019
actually causing more problem by what you think you were
601
00:33:49.059 --> 00:33:52.500
doing right, you know, and it sucks that we're involved
602
00:33:52.539 --> 00:33:54.980
in that and around it. But one of the things
603
00:33:55.049 --> 00:33:56.970
I wanted to ask you, because you brought this up
604
00:33:57.029 --> 00:34:00.630
about looking at blood work, because everything I do revolves
605
00:34:00.670 --> 00:34:02.890
around data, blood panels, everything. I do a lot of
606
00:34:02.910 --> 00:34:07.299
hormone optimization. So if we're looking at judging or gauging
607
00:34:07.500 --> 00:34:11.440
a healthy or unhealthy immune system. What blood markers are
608
00:34:11.460 --> 00:34:13.500
we looking for that could potentially be off that might
609
00:34:13.559 --> 00:34:15.199
indicate your immune system screwed up?
610
00:34:15.519 --> 00:34:18.980
I published a paper in 2015 on this, on aging
611
00:34:19.139 --> 00:34:22.960
and the immune system. And the three important ones are,
612
00:34:23.139 --> 00:34:24.480
one of them is not that easy to access, but
613
00:34:24.500 --> 00:34:27.739
you can get it, is high sensitivity CRP. Very easy
614
00:34:27.780 --> 00:34:30.449
to test. Probably the most important one. The second one
615
00:34:30.610 --> 00:34:33.650
is tumor necrosis factor alpha. Tumor necrosis factor alpha is
616
00:34:33.690 --> 00:34:38.030
indicative of A chronic inflammatory state, a state of not
617
00:34:38.110 --> 00:34:41.230
functioning correctly. That's why actually there's a drug out there
618
00:34:41.329 --> 00:34:44.550
for autoimmune diseases that cuts that off. The problem with
619
00:34:44.610 --> 00:34:48.119
cutting tumor necrosis factor out is basically alpha out is
620
00:34:48.340 --> 00:34:51.039
you put yourself in an immune suppressed state. You put
621
00:34:51.059 --> 00:34:54.599
yourself more susceptible to the big C word cancer we
622
00:34:54.619 --> 00:34:57.820
talked about earlier. And that's a bad one. The last
623
00:34:57.900 --> 00:35:00.920
one is interleukin-6. The IL-6 is a lot harder to
624
00:35:01.139 --> 00:35:03.739
test too, but you can go out there, there's tests
625
00:35:03.780 --> 00:35:06.989
available that you can actually look at it because those
626
00:35:07.090 --> 00:35:12.809
three are indicative of age-associated diseases. And there's thousands, there's
627
00:35:12.849 --> 00:35:15.809
a ton of papers out there, published peer-reviewed data on
628
00:35:16.269 --> 00:35:21.769
thousands of patients that if these are inflamed, you are
629
00:35:22.110 --> 00:35:25.769
either in or you're heading towards a neurodegenerative disease or
630
00:35:25.809 --> 00:35:26.909
a cardiovascular disease.
631
00:35:27.570 --> 00:35:30.449
Yeah, it's wild how every single thing that you're looking
632
00:35:30.489 --> 00:35:34.469
for revolves around inflammation. It seems like every single problem,
633
00:35:34.539 --> 00:35:38.400
if you're looking for an indicator, that the high-sensitivity C-reactive
634
00:35:38.420 --> 00:35:39.719
protein tells you a lot.
635
00:35:39.940 --> 00:35:42.420
Yep, it tells you a ton. And there's, you know,
636
00:35:42.460 --> 00:35:45.440
other simple ones is you can look at a sedimentation rate,
637
00:35:46.219 --> 00:35:49.719
you can look at fibrinogen, And you can look at homocysteine.
638
00:35:49.760 --> 00:35:52.420
Homocysteine is too a big one that people don't spend
639
00:35:52.460 --> 00:35:54.659
enough time testing and looking at too. If you look
640
00:35:54.699 --> 00:35:57.929
at those, all of those together, you got a complete
641
00:35:58.119 --> 00:36:00.409
package of some good blood work. And then the other
642
00:36:00.429 --> 00:36:02.630
thing is understanding is that if they tell you you're
643
00:36:02.650 --> 00:36:04.750
within range, where are you at within that range? Because
644
00:36:04.789 --> 00:36:08.409
blood exams have this massive range of individuals that are
645
00:36:08.449 --> 00:36:11.880
really young and individuals that are really old. Well, guess what?
646
00:36:11.909 --> 00:36:15.679
If you're 40 years old and, or 45 years old,
647
00:36:15.800 --> 00:36:18.800
and you're close to the top of that range, something's
648
00:36:18.820 --> 00:36:19.480
not quite right.
649
00:36:19.519 --> 00:36:21.980
You shouldn't be there. And the way they judge these
650
00:36:22.079 --> 00:36:24.079
ranges anymore. And once again, cause I do a lot
651
00:36:24.119 --> 00:36:26.769
of stuff with testosterone for men and women, and some
652
00:36:26.789 --> 00:36:29.269
of these ranges are just out of fricking control.
653
00:36:29.349 --> 00:36:30.250
It makes me mad.
654
00:36:30.849 --> 00:36:33.750
I mean, telling somebody that you're functionable or doing good
655
00:36:33.769 --> 00:36:36.949
with like 190 or 200 testosterone level is just out
656
00:36:36.969 --> 00:36:39.420
of line. And I'm wondering how do they, how do
657
00:36:39.460 --> 00:36:43.449
they gauge? And because you know this, they're constantly changing
658
00:36:43.489 --> 00:36:45.809
the ratios and where you fall. How are they gauging
659
00:36:45.849 --> 00:36:48.579
this and coming up with what falls into being acceptable
660
00:36:49.159 --> 00:36:49.539
in range?
661
00:36:49.760 --> 00:36:53.039
Well, I mean, it's all age. They've gone through all
662
00:36:53.059 --> 00:36:55.820
the way from pediatric adults and they come up with
663
00:36:55.840 --> 00:36:58.820
the reference range. And that's where they'll gauge you between, well,
664
00:36:58.840 --> 00:37:01.909
you're somewhere between here, you're healthy. Based on these individuals
665
00:37:01.949 --> 00:37:05.610
being relatively healthy, anything out of this range, you're not healthy.
666
00:37:05.670 --> 00:37:08.190
But exactly what you just said, I don't want to
667
00:37:08.230 --> 00:37:10.969
be a 50 or a six, I'm a six, I'm
668
00:37:10.969 --> 00:37:13.050
60 years old. I don't want to be 60 and
669
00:37:13.110 --> 00:37:17.130
have the testosterone of 150 because they're telling me you're
670
00:37:17.170 --> 00:37:20.309
within your age. I want to be feeling like my
671
00:37:20.349 --> 00:37:22.030
testosterone is when I was 30.
672
00:37:22.030 --> 00:37:22.309
Yeah.
673
00:37:22.469 --> 00:37:24.530
When I was 35, 40, like that's when I want
674
00:37:24.550 --> 00:37:26.369
to be, I want to be in that range. And
675
00:37:26.409 --> 00:37:29.389
that's a healthier range, I believe for me to sustain
676
00:37:29.869 --> 00:37:32.739
that youthfulness. That's, it's the same thing with the testing.
677
00:37:33.110 --> 00:37:34.739
You want to be in a better range. It's one
678
00:37:34.760 --> 00:37:37.289
that you want it a little bit more pinpointed in
679
00:37:37.329 --> 00:37:41.289
that median area where it's a safer bet to look at.
680
00:37:42.449 --> 00:37:44.570
Okay, I'm going to shift here. I'm going to ask
681
00:37:44.610 --> 00:37:46.300
you a number here, and I'm sure you know it.
682
00:37:47.019 --> 00:37:48.960
And this is one of the things that just fascinated
683
00:37:49.000 --> 00:37:50.940
the hell out of me when I really put my
684
00:37:51.119 --> 00:37:54.320
efforts into studying more biology and cellular biology.
685
00:37:54.719 --> 00:37:57.340
How many cells do we have in our body? I
686
00:37:57.380 --> 00:37:59.840
don't know the exact number. It's trillions. It's trillions, yeah.
687
00:37:59.920 --> 00:38:03.739
It's insane. It's an insane number of cells, because if
688
00:38:03.780 --> 00:38:08.199
you think of just in... In blood flow, apoptosis, natural
689
00:38:08.219 --> 00:38:14.239
cell death, happens about 300 billion times a day. So
690
00:38:14.449 --> 00:38:17.239
it's trillions and trillions. I believe in the brain alone,
691
00:38:17.260 --> 00:38:22.710
a trillion cells. There's an insane amount of cells and
692
00:38:22.909 --> 00:38:26.889
the complex processes of cells in our body that happens
693
00:38:26.949 --> 00:38:32.050
on a daily basis to maintain that appropriate temperature, that
694
00:38:32.070 --> 00:38:35.300
appropriate pH, It's this crazy.
695
00:38:35.539 --> 00:38:37.719
When I started to look at science more of like
696
00:38:37.760 --> 00:38:41.650
this was God's design as opposed to me misconstruing everything
697
00:38:41.670 --> 00:38:43.789
that it was. And I realized the intricacy of how
698
00:38:43.869 --> 00:38:47.889
detailed our body is put together and understanding that structure
699
00:38:48.090 --> 00:38:52.409
and what it goes through on a second by second basis.
700
00:38:52.449 --> 00:38:53.969
I don't even want to say a daily basis, like
701
00:38:54.110 --> 00:38:56.860
every second from the heart to the cells to everything else.
702
00:38:56.940 --> 00:39:00.820
I mean, it is absolutely mind blowing. And learning about
703
00:39:00.980 --> 00:39:04.349
cell structure and understanding their health is everything. And that's
704
00:39:04.409 --> 00:39:08.989
why we talked about, you know, different cellular health aspects.
705
00:39:09.050 --> 00:39:12.150
And people don't understand what a cell goes through, how
706
00:39:12.230 --> 00:39:14.670
it dies or how it becomes a zombie cell or
707
00:39:14.730 --> 00:39:18.000
sticks around and how when those are off and that
708
00:39:18.079 --> 00:39:21.699
function is off, we're off. Right. So like, for instance, mitochondria,
709
00:39:21.699 --> 00:39:24.199
how important is mitochondria as part of a cell?
710
00:39:24.199 --> 00:39:24.909
And do me this.
711
00:39:24.909 --> 00:39:27.809
Because I'm curious, because that's kind of the big thing
712
00:39:27.809 --> 00:39:30.469
is to talk about mitochondria. and I think rightfully so.
713
00:39:30.530 --> 00:39:32.780
But what are the most important parts of a cell?
714
00:39:32.800 --> 00:39:35.179
Because to me, the cellular membrane would be one of
715
00:39:35.199 --> 00:39:37.409
the most important parts. I mean, isn't that protecting it?
716
00:39:37.639 --> 00:39:40.519
So please, break down a cell structure and what's the
717
00:39:40.579 --> 00:39:42.280
most important parts and how we keep it safe.
718
00:39:42.739 --> 00:39:45.940
I can't... It's really hard to say what's the most
719
00:39:46.000 --> 00:39:50.469
important part because the cell... has a machinery in it
720
00:39:50.849 --> 00:39:54.789
and the cell has to produce proteins, has to be
721
00:39:54.829 --> 00:40:00.769
able to produce functional signaling, functional cues, you know, these
722
00:40:00.809 --> 00:40:03.170
little particles that are called endosomes inside of a cell.
723
00:40:03.630 --> 00:40:07.300
A cell produces a signal for another cell and it's
724
00:40:07.519 --> 00:40:11.179
enveloped in a small type of a membrane and then
725
00:40:11.260 --> 00:40:13.820
it's shot out. And this is how we get long
726
00:40:13.860 --> 00:40:16.900
distance signaling from one cell to another cell. That's really important.
727
00:40:16.940 --> 00:40:18.820
That's the importance of the cell membrane because the cell
728
00:40:18.860 --> 00:40:21.800
membrane is that lipid bilayer. But the mitochondria is the
729
00:40:21.840 --> 00:40:25.000
powerhouse of the cell. Mitochondria is really, really important. The
730
00:40:25.059 --> 00:40:28.760
ribosomes are really, really important. The endoplasmic reticular is really,
731
00:40:28.780 --> 00:40:32.860
really important. All of it has function for protein and
732
00:40:32.980 --> 00:40:38.170
for machinery to sustain life. So the purpose of, you know,
733
00:40:38.179 --> 00:40:39.989
the cells have to turn over on a regular basis
734
00:40:40.030 --> 00:40:42.570
because when a cell doesn't become or if it's not
735
00:40:42.630 --> 00:40:45.630
functioning correctly, it has to naturally turn over. And this
736
00:40:45.670 --> 00:40:49.840
is apoptosis. You know, it has to transpire. It transpires
737
00:40:49.889 --> 00:40:52.739
on a daily basis because it has to. It needs
738
00:40:53.260 --> 00:40:55.039
the correct cells to function appropriately.
739
00:40:55.679 --> 00:40:59.300
Every single cell has all of these important components and structure,
740
00:40:59.320 --> 00:41:01.719
and we got trillions of them. So to think about
741
00:41:01.800 --> 00:41:03.699
what it takes for a cell to function and how
742
00:41:03.739 --> 00:41:06.179
many moving parts there are and how many things we
743
00:41:06.219 --> 00:41:09.139
have to be aware of. So how difficult is it
744
00:41:09.199 --> 00:41:12.610
for us to, the duration of our life to keep
745
00:41:12.690 --> 00:41:16.469
cellular health. I mean, how difficult is that? How important
746
00:41:16.530 --> 00:41:18.730
is that as we age? It's one of the most
747
00:41:18.789 --> 00:41:19.550
important things.
748
00:41:20.449 --> 00:41:21.570
You know, that's why a lot of times we go
749
00:41:21.610 --> 00:41:25.500
back to diet is, you know, one of the only
750
00:41:25.559 --> 00:41:28.760
things that preserves longevity and that we know in the
751
00:41:28.800 --> 00:41:32.820
context of telomeres is basically caloric restriction. And if you
752
00:41:32.880 --> 00:41:35.670
stop eating, you slow down cell division. Believe it or not,
753
00:41:35.690 --> 00:41:40.090
it even decreases IGF, which causes cells to proliferate. It
754
00:41:40.139 --> 00:41:45.809
slows down that process. If you think of animal species
755
00:41:45.829 --> 00:41:49.349
that live long time, what do those animals do? Like turtles,
756
00:41:49.550 --> 00:41:55.179
Darwin turtles. These turtles basically sleep a ton. They eat
757
00:41:55.300 --> 00:41:58.760
very little. And this preserves a long lifespan for them.
758
00:41:58.960 --> 00:42:01.719
Slow and steady, just like the turtle. Slow and steady.
759
00:42:01.880 --> 00:42:06.239
It's very, very similar in the human being of slow
760
00:42:06.280 --> 00:42:09.690
down internally. I'm not talking about stopping exercise or anything.
761
00:42:10.119 --> 00:42:14.659
I'm talking about slowing down internally what's transpiring and that's
762
00:42:14.739 --> 00:42:18.960
done by eating correctly, watching what you're consuming on a
763
00:42:19.019 --> 00:42:24.840
regular basis, sleeping correctly because sleep is the ability to recover.
764
00:42:25.039 --> 00:42:28.199
You have to understand that aspect of it. People that
765
00:42:28.219 --> 00:42:32.960
complain to me about spending money on mattresses, I'm like, no,
766
00:42:33.400 --> 00:42:35.719
double down on having the best mattress you can get
767
00:42:35.840 --> 00:42:38.099
and the best sleep you can get because you need
768
00:42:38.119 --> 00:42:41.429
that for recovery. That is part of longevity that's part
769
00:42:41.469 --> 00:42:43.630
of living well you're not going to recover if you
770
00:42:43.650 --> 00:42:45.869
don't sleep well if you don't eat well you're not
771
00:42:45.889 --> 00:42:48.289
going to recover correctly you're going to feel like.
772
00:42:48.230 --> 00:42:50.389
Crap because it affects your immune system and i've come
773
00:42:50.429 --> 00:42:53.050
to understand this by being a person that never takes
774
00:42:53.090 --> 00:42:55.809
a break or never rests is how important that is
775
00:42:56.449 --> 00:43:01.230
to your vitality your inflammation everything so spending money on
776
00:43:01.250 --> 00:43:03.150
the mattress would make the most sense because you use
777
00:43:03.170 --> 00:43:07.440
it the most forever so man you Some of the
778
00:43:07.500 --> 00:43:09.900
points you bring up may seem obvious at times, but
779
00:43:09.920 --> 00:43:11.980
they're the most important things. And you hit the nail,
780
00:43:12.000 --> 00:43:12.940
like every single time.
781
00:43:12.980 --> 00:43:14.250
I love it, dude. I love it.
782
00:43:15.460 --> 00:43:19.239
So that one more part of cells before we move on,
783
00:43:19.239 --> 00:43:21.099
because I know you had some new studies that you
784
00:43:21.119 --> 00:43:22.860
wanted to talk about, but I would just like to
785
00:43:22.900 --> 00:43:27.119
give a small little breakdown. You know, there's, there's supplements
786
00:43:27.159 --> 00:43:29.250
we can take for cellular health. There's things that we
787
00:43:29.289 --> 00:43:33.170
can do, but I think the understanding.
788
00:43:32.590 --> 00:43:33.429
Is what's missing.
789
00:43:33.809 --> 00:43:36.190
Right? And everybody just wants to take a supplement to
790
00:43:36.230 --> 00:43:39.469
fix this or fix that. Just a simple, you know,
791
00:43:39.489 --> 00:43:43.719
we know like fasting, you said stimulates autophagy. How do
792
00:43:43.739 --> 00:43:47.780
we stimulate mitophagy? How do we stop senescence or mitigate it?
793
00:43:47.840 --> 00:43:51.219
You know, what can we do to take control early on?
794
00:43:51.239 --> 00:43:54.369
Because I'm a big try to tackle this early before
795
00:43:54.409 --> 00:43:57.409
it gets too late guy. So give us some of
796
00:43:57.469 --> 00:44:00.030
your plans or insights on how to keep this going.
797
00:44:00.250 --> 00:44:02.030
Being proactive versus being reactive.
798
00:44:02.090 --> 00:44:07.769
Yes. Basically, Important aspect is fasting is good because fasting
799
00:44:07.909 --> 00:44:11.090
activates autophagy and it gives the body a break. Autophagy
800
00:44:11.690 --> 00:44:15.110
gets rid of those bad signals, those bad things that
801
00:44:15.130 --> 00:44:18.349
are released by those zombie cells, those senescent cells that
802
00:44:18.369 --> 00:44:22.230
are there that cause more havoc. The reason why we
803
00:44:22.289 --> 00:44:24.590
know that those signals are bad is for instance, in
804
00:44:24.630 --> 00:44:27.469
a Petri dish and in our lab, we've done this experiment.
805
00:44:27.949 --> 00:44:31.190
If I mix a zombie, the senescent cell with a
806
00:44:31.289 --> 00:44:34.510
very young cell and I mix it together, what I get,
807
00:44:34.630 --> 00:44:37.570
the physical aspect, what's called the phenotype, the feature I
808
00:44:37.610 --> 00:44:41.130
get from the new cells are old cells. And it's
809
00:44:41.170 --> 00:44:45.300
because those signalers are causing the young cells to become old.
810
00:44:45.800 --> 00:44:49.579
I see. So if we can eliminate that aspect of
811
00:44:49.639 --> 00:44:55.280
some of those signals, which diet helps tremendously, exercise helps tremendously,
812
00:44:56.119 --> 00:44:58.119
there's a lot of things that you can actually do
813
00:44:58.340 --> 00:45:01.739
on a daily basis that really doesn't cost much money
814
00:45:02.059 --> 00:45:05.349
that you can slow down that process of the formation
815
00:45:05.369 --> 00:45:07.909
of senescence, that feeling that you feel bad, you know,
816
00:45:07.929 --> 00:45:11.659
these types of things, even breathing exercises. You know, what
817
00:45:11.679 --> 00:45:14.539
are you doing when you do breathing exercise or what
818
00:45:14.559 --> 00:45:17.699
are you doing when you're sprinting? Why do you feel
819
00:45:17.760 --> 00:45:21.599
so well after you walk or you've sprinted or whatever?
820
00:45:21.880 --> 00:45:25.530
You know why? Because you've increased blood flow through your
821
00:45:25.550 --> 00:45:29.829
body and you've increased your intake of oxygen. I'm going
822
00:45:29.849 --> 00:45:32.130
to give you a I would say rapid fire.
823
00:45:32.150 --> 00:45:33.889
I know it's going to take you a second to
824
00:45:33.989 --> 00:45:36.050
answer these, but I'm going to give you some situations
825
00:45:36.110 --> 00:45:39.550
and scenarios of either things we consume and or do
826
00:45:39.789 --> 00:45:42.239
and practice every day. And you tell me how it
827
00:45:42.300 --> 00:45:45.860
relates to good or bad, like what it does to
828
00:45:45.940 --> 00:45:51.119
our cellular health and maybe in and our immune system, please.
829
00:45:51.139 --> 00:45:53.619
Because I doubt this would be highly beneficial for people
830
00:45:53.659 --> 00:45:56.670
that are doing this shit. Alcohol consumption.
831
00:45:57.289 --> 00:46:03.309
Horrible. It's actually cytotoxic. Cardiac toxic more than anything else,
832
00:46:03.389 --> 00:46:06.090
but it's very cytotoxic for you. It affects your metabolic
833
00:46:06.110 --> 00:46:10.130
function in the liver, which indirectly affects your immune system.
834
00:46:10.409 --> 00:46:12.610
Really bad for you. And it affects your sleep. You
835
00:46:12.650 --> 00:46:14.630
might pass out, fall asleep quickly. You are going to
836
00:46:14.650 --> 00:46:15.000
wake up.
837
00:46:15.010 --> 00:46:17.309
You're going to feel horrible. Taps the hell out of
838
00:46:17.329 --> 00:46:20.769
the liver. Smoking, let's say, cigarettes first.
839
00:46:21.409 --> 00:46:24.769
Cigarettes are basically toxic, completely toxic to the lung, and
840
00:46:24.789 --> 00:46:28.730
then completely toxic to the vasculature system, which then indirectly
841
00:46:28.769 --> 00:46:32.110
affects the immune system also. Smoking in general. I'm even
842
00:46:32.130 --> 00:46:35.099
talking about vaping. That's right. Vaping is bad. All of it.
843
00:46:35.269 --> 00:46:38.260
And any type you're burning something and you're inhaling it,
844
00:46:38.449 --> 00:46:42.389
it's bad. Would that go for marijuana as well? Smoking
845
00:46:42.429 --> 00:46:44.909
marijuana can also be bad for you too. Okay. And
846
00:46:44.929 --> 00:46:47.789
there's more and more studies now coming out with that. Yes. Yeah.
847
00:46:47.849 --> 00:46:49.190
I was one of those that used to try to
848
00:46:49.230 --> 00:46:51.980
tell myself it was okay when I finally realized.
849
00:46:51.679 --> 00:46:52.420
That was bullshit.
850
00:46:52.519 --> 00:46:54.559
But you know, that was, that's one of those things
851
00:46:54.579 --> 00:46:56.679
you convince yourself because you're doing something. So I was
852
00:46:56.719 --> 00:47:01.199
curious about your thought on that. What about pharmaceutical drugs.
853
00:47:02.980 --> 00:47:07.099
And I'm talking, we're talking, let me clarify that. The
854
00:47:07.260 --> 00:47:10.809
pharmaceutical drugs that are narcotic type drugs, like your Vicodins,
855
00:47:10.829 --> 00:47:13.690
your Percocets, you know, things that people abuse, Xanax, some
856
00:47:13.730 --> 00:47:14.690
of those types of things.
857
00:47:14.869 --> 00:47:19.610
Horrible for you. Dependent, temporary master problem, don't deal with
858
00:47:19.670 --> 00:47:23.280
any problem, and cause a ton of secondary effects. When
859
00:47:23.300 --> 00:47:25.739
we talk about secondary effects, we talk about liver toxicity,
860
00:47:25.800 --> 00:47:29.800
we talk about kidney toxicity, cardiovascular toxicity also. in the
861
00:47:29.860 --> 00:47:35.440
vast majority of all of those. Some pharmaceuticals are okay,
862
00:47:35.559 --> 00:47:39.619
but the vast majority out there are basically relatively, you know,
863
00:47:40.079 --> 00:47:41.840
they're bad for you. Some people have to be on
864
00:47:41.889 --> 00:47:44.929
them because of specific diseases and it's ultimately a balance
865
00:47:44.969 --> 00:47:47.269
of quality of life or not. But you have to
866
00:47:47.309 --> 00:47:49.750
look at that balance of what is the trade-off. For instance,
867
00:47:49.769 --> 00:47:52.289
in the context of autoimmune diseases, the majority of them
868
00:47:52.710 --> 00:47:55.849
suppress the immune system. The secondary effect of suppressing the
869
00:47:55.869 --> 00:48:00.679
immune system is basically cancer, other infectious diseases, et cetera,
870
00:48:00.699 --> 00:48:04.860
et cetera. Pick your poison. Tylenol. Bad because, I got
871
00:48:04.900 --> 00:48:11.449
a little story. Well, bad because, so it may possibly
872
00:48:11.530 --> 00:48:17.269
resolve a headache, but it is very kidney toxic and
873
00:48:17.570 --> 00:48:20.010
liver toxic. So much so that I'm not going to
874
00:48:20.050 --> 00:48:23.969
name any companies, but I remember years ago, I was
875
00:48:24.150 --> 00:48:27.130
at a big March event. In a foreign country. And
876
00:48:27.150 --> 00:48:32.170
I was told by somebody, we live off of individuals
877
00:48:32.570 --> 00:48:37.269
that take Tylenol and ibuprofen. Oh, man. And it's because
878
00:48:37.329 --> 00:48:41.980
it wrecks your kidneys and your organs. Sunlight. Phenomenal for you.
879
00:48:42.820 --> 00:48:45.099
Phenomenal for you. One of the best things you can take,
880
00:48:45.179 --> 00:48:48.699
you just have to watch in moderation, especially as you age.
881
00:48:48.840 --> 00:48:51.599
You really have to be cautious with that aspect of it.
882
00:48:52.039 --> 00:48:55.880
But sunlight, there is nothing more important than specific UVs
883
00:48:56.440 --> 00:48:59.070
and the ones in the morning, regardless of it not
884
00:48:59.119 --> 00:49:03.090
being sunny out, get out there during daybreak. It's the
885
00:49:03.190 --> 00:49:07.289
best form of energy you can actually get. Daily walking. Oh, it's,
886
00:49:08.050 --> 00:49:09.250
there is nothing better than walking.
887
00:49:09.269 --> 00:49:10.090
I agree.
888
00:49:10.409 --> 00:49:12.630
Period. There is nothing better. Before, like, you'd get, you know,
889
00:49:12.650 --> 00:49:14.769
you'd get back surgery, you'd have whatever. Oh, no, you
890
00:49:14.789 --> 00:49:16.170
got to be, you got to lay down for a while.
891
00:49:16.489 --> 00:49:18.550
Now it's the complete opposite. It heals you so much quicker.
892
00:49:19.130 --> 00:49:21.550
Get out there and walk. If you have pain, it
893
00:49:21.570 --> 00:49:23.570
increases blood flow. It helps healing.
894
00:49:24.340 --> 00:49:24.679
Walk.
895
00:49:25.019 --> 00:49:26.340
Walking is the best thing you can do.
896
00:49:26.699 --> 00:49:28.679
I walk a lot, but, you know, it's four or
897
00:49:28.719 --> 00:49:30.260
five miles a day. I don't say everybody has to
898
00:49:30.300 --> 00:49:32.079
do that. But when I made that change, because in
899
00:49:32.139 --> 00:49:33.960
my head, I was always like, oh, I got to
900
00:49:33.980 --> 00:49:37.000
do all this hardcore, you know, run, run and all
901
00:49:37.019 --> 00:49:40.280
of this. Dude, it's changed my life. I mean, really,
902
00:49:40.480 --> 00:49:43.780
it really, really has. And multitude of reasons why not.
903
00:49:43.800 --> 00:49:46.519
And the movement and everything is one, but the ability
904
00:49:46.579 --> 00:49:49.920
for me to then really relate with the surroundings and
905
00:49:49.940 --> 00:49:52.659
the earth, I spend it, you know, prayer time doing
906
00:49:52.679 --> 00:49:53.239
that or whatever.
907
00:49:53.280 --> 00:49:55.679
And that's not for everybody. Fine. But that for me, it's,
908
00:49:56.039 --> 00:49:59.139
it's a, like a decompression from everything that's around me.
909
00:49:59.659 --> 00:50:02.300
So it's soothing to the soul on top of the, that,
910
00:50:02.360 --> 00:50:04.539
that makes two of us. I was in the military.
911
00:50:04.559 --> 00:50:07.679
I would run, I was a combat engineer, demolition specialist
912
00:50:07.719 --> 00:50:11.789
in the army. I would run six to 15 miles.
913
00:50:11.849 --> 00:50:14.630
It just range to a day. Yeah. When I left
914
00:50:14.670 --> 00:50:17.809
the military, I still ran, ran, ran at some juncture.
915
00:50:18.389 --> 00:50:21.519
You have to stop because it breaks down the joints.
916
00:50:22.059 --> 00:50:24.360
The switch is exactly what you said. For instance, I
917
00:50:24.420 --> 00:50:26.579
have a wonderful, I love the hell out of my dog.
918
00:50:26.599 --> 00:50:30.639
I have a great Doberman. They're crazy, active dogs. He
919
00:50:30.719 --> 00:50:32.860
forces me every morning to get out there. I live
920
00:50:32.880 --> 00:50:35.780
in the Hills where, you know, walking, running on a
921
00:50:35.820 --> 00:50:39.050
daily basis, hiking through the Hills. It completely, it's the
922
00:50:39.239 --> 00:50:41.840
best way to start off your day. Clears your mind,
923
00:50:42.340 --> 00:50:46.679
you know, get that fresh air, get that atmosphere, look
924
00:50:46.739 --> 00:50:50.559
up in the sky, you're alive, touch the ground, get
925
00:50:50.599 --> 00:50:52.800
the grounding aspect of it. The best way to start
926
00:50:52.840 --> 00:50:55.019
off your day. I talk to my mom all the time.
927
00:50:55.539 --> 00:50:57.960
Like I tell her, mom, did you go outside today?
928
00:50:58.820 --> 00:51:01.260
Did you do some breathing exercises? It's going to shift
929
00:51:01.280 --> 00:51:03.260
your complete mindset and you're going to feel so much better.
930
00:51:03.280 --> 00:51:05.860
I have a big smile because I love animals so much.
931
00:51:05.900 --> 00:51:11.010
That's why I have the huge smile. Last one. There's
932
00:51:11.050 --> 00:51:14.550
nothing more important than being grateful. I mean, and our
933
00:51:14.570 --> 00:51:16.650
common friend, I love when he came up with the,
934
00:51:16.969 --> 00:51:18.269
and it's funny because people don't know what the hell
935
00:51:18.289 --> 00:51:19.949
vitamin G is. You know what's funny?
936
00:51:20.469 --> 00:51:22.980
I was moderating a panel at Biohackers World and I
937
00:51:23.019 --> 00:51:25.079
told them, I said, you know, you've given me this,
938
00:51:25.139 --> 00:51:27.760
now I'm stealing. I gave a speech on vitamin G
939
00:51:27.800 --> 00:51:30.539
and the importance of gratitude because it was a panel
940
00:51:30.579 --> 00:51:33.659
discussing what can you do every day that's like not
941
00:51:33.679 --> 00:51:35.429
supposed to cost you a bunch of money or something
942
00:51:35.449 --> 00:51:37.409
that's easy to implement that you're not doing.
943
00:51:37.429 --> 00:51:42.500
And to me, that is number one. It's number one. Yeah. So, okay.
944
00:51:42.840 --> 00:51:45.900
I know we're winding down. Can you give me a
945
00:51:45.940 --> 00:51:48.179
little insight? Because you kind of teased a little bit
946
00:51:48.219 --> 00:51:50.360
before we started talking about some new studies that you
947
00:51:50.400 --> 00:51:51.059
were working on.
948
00:51:51.079 --> 00:51:56.179
Yeah. So we're a company that's focused on regenerative medicine,
949
00:51:56.199 --> 00:51:58.929
cell therapies. We have multiple clinical studies in autoimmune diseases.
950
00:51:59.969 --> 00:52:03.150
And we're now working with the signaling cues of the
951
00:52:03.210 --> 00:52:06.550
different cells, which we have a phenomenal topical that works
952
00:52:06.989 --> 00:52:10.800
in cosmetics. works phenomenal in orthopedics that we're actually going
953
00:52:10.840 --> 00:52:15.000
into clinical studies on too. But we are now working
954
00:52:15.400 --> 00:52:18.519
on the next level, like these natural killer cells that
955
00:52:18.539 --> 00:52:21.719
we briefly mentioned. We're producing the signaling cues from them
956
00:52:21.940 --> 00:52:24.539
and we're seeing some exciting news in the context of,
957
00:52:24.559 --> 00:52:27.059
because it'll make it a lot more affordable for everybody
958
00:52:27.079 --> 00:52:30.239
in the context of senescence. So we're seeing some really,
959
00:52:30.300 --> 00:52:35.119
really exciting news with that, including seeing, for instance, which
960
00:52:35.159 --> 00:52:37.030
would be a game changer. We talked a little bit
961
00:52:37.050 --> 00:52:39.719
about going out in the sun, if you're exposed too much,
962
00:52:39.739 --> 00:52:42.400
that you can possibly get a melanoma is we're seeing
963
00:52:42.500 --> 00:52:46.400
some of these guidance cues wiping out melanoma. And it
964
00:52:46.440 --> 00:52:49.440
would just be as simple as the context is putting
965
00:52:49.460 --> 00:52:52.460
this stuff on skin, getting melanoma and the skin has
966
00:52:52.500 --> 00:52:53.510
to regenerate on its own.
967
00:52:54.030 --> 00:52:54.530
Wow.
968
00:52:54.719 --> 00:52:57.090
Versus getting somebody to carve, which is what they do.
969
00:52:57.429 --> 00:52:59.449
They're removing chunks of your skin out when you have this.
970
00:53:00.150 --> 00:53:02.869
So we have some pretty exciting stuff that we're, you know,
971
00:53:02.889 --> 00:53:05.250
we've been testing and looking at, and it's, it seems
972
00:53:05.269 --> 00:53:07.849
heading in the right direction. How long do you think
973
00:53:07.889 --> 00:53:10.489
something like that to be available? Quite a while or?
974
00:53:10.690 --> 00:53:12.789
Quite a while. Really? Quite a while. But we, our
975
00:53:12.829 --> 00:53:18.179
cell therapeutics, our study that's furthest along, we're hoping with
976
00:53:18.380 --> 00:53:20.639
good results, because we're in what's called the phase two,
977
00:53:20.659 --> 00:53:23.579
three clinical study transition study is within the next couple
978
00:53:23.599 --> 00:53:26.340
of years, we might have an approval. Really? Yeah. So
979
00:53:26.360 --> 00:53:29.739
you've got optimism, man, at least. Yes, we are because
980
00:53:29.760 --> 00:53:33.329
we're seeing a phenomenal safety profile. no adverse events, which
981
00:53:33.389 --> 00:53:36.989
is fantastic, which is rare. And we're seeing some really
982
00:53:37.070 --> 00:53:40.659
good clinical benefit where I found an angel many, many
983
00:53:40.699 --> 00:53:43.920
years ago that helped fund this entire study. She suffered
984
00:53:43.940 --> 00:53:47.239
from the disease. She's actually seen at Brigham and Women's
985
00:53:47.460 --> 00:53:50.940
Hospital in Boston. And she's in remission of disease now
986
00:53:51.000 --> 00:53:53.429
for four years, which she was in bad shape when
987
00:53:53.469 --> 00:53:56.389
I first met her. Off of all her meds, immunosuppressants,
988
00:53:56.610 --> 00:54:00.070
all of that with this particular type of autoimmune disease.
989
00:54:00.929 --> 00:54:03.940
So it's We're getting some promising things in the context
990
00:54:03.960 --> 00:54:06.460
of cell therapeutics. I love it. I love to hear it.
991
00:54:07.090 --> 00:54:09.929
Before we stop, I want to ask and I want
992
00:54:09.949 --> 00:54:14.579
to do immune system first, cellular health second. So and
993
00:54:14.619 --> 00:54:16.460
I want to preface this because we always have to
994
00:54:16.519 --> 00:54:20.539
be careful. Supplements are good. Supplements, meaning they're used to
995
00:54:20.639 --> 00:54:23.679
supplement what we discussed. The things that we discussed first
996
00:54:23.739 --> 00:54:25.880
are the most important, but let's look at this from
997
00:54:25.920 --> 00:54:30.110
a secondary perspective as the enhancement. What type of supplements
998
00:54:30.170 --> 00:54:32.670
would you recommend someone to look at that would maybe
999
00:54:32.730 --> 00:54:36.010
be staples for you for boosting the immune system?
1000
00:54:36.329 --> 00:54:41.110
Anacetylcysteine. I think it's beyond important because it helps clear
1001
00:54:41.920 --> 00:54:44.860
oxidative stress. Okay, good. I take that. Okay. I take
1002
00:54:44.900 --> 00:54:47.599
that too. Yes. It's one of the biggest important ones.
1003
00:54:48.010 --> 00:54:50.449
It's crazy because you OD on what we just talked about,
1004
00:54:50.489 --> 00:54:52.889
Tylenol or Ibuprofen, you go to the hospital, this is
1005
00:54:52.909 --> 00:54:56.719
what they're going to give you. Wow. Okay. To clear it. Sweet.
1006
00:54:56.860 --> 00:55:00.099
That's one of the important ones. Vitamin D is critical.
1007
00:55:00.179 --> 00:55:07.570
I don't care how much time. In combination with K. Yeah. D3, K2. K2. Yeah.
1008
00:55:07.590 --> 00:55:11.210
It's got to be in combination because, and especially good
1009
00:55:11.269 --> 00:55:15.510
for women because it helps sequester hormones. calcium into bone.
1010
00:55:15.690 --> 00:55:18.070
So it's really, really important in that combination, not on
1011
00:55:18.130 --> 00:55:20.929
its own. You got to watch it. Really, really important.
1012
00:55:21.070 --> 00:55:23.289
I take a particular one that I love and I
1013
00:55:23.349 --> 00:55:25.090
swear by it and I have two of my family
1014
00:55:25.110 --> 00:55:30.340
members on it. And it's, it's designed to help basically
1015
00:55:31.059 --> 00:55:36.139
increase or help the vasculature aspect, you know, of it.
1016
00:55:36.239 --> 00:55:40.619
And it's a particular supplement that it's, um, what was
1017
00:55:40.639 --> 00:55:42.579
the name of it? We talked about this when we
1018
00:55:42.619 --> 00:55:46.289
had a call. I remember you talking about it. Arterial cell. Yes.
1019
00:55:46.550 --> 00:55:48.449
I still have it up on my computer to order
1020
00:55:48.489 --> 00:55:51.349
and I never did. Arterial cell. You know, my mom
1021
00:55:51.369 --> 00:55:53.469
started taking it. It helped her blood pressure. I started
1022
00:55:53.489 --> 00:55:55.719
taking it and it helped lower my blood pressure a
1023
00:55:55.719 --> 00:55:57.050
little bit, which my blood pressure was fine, but I
1024
00:55:57.099 --> 00:55:59.320
helped lower it a little bit more. My sister's now
1025
00:55:59.440 --> 00:56:01.320
on it. She's getting the same exact thing from it.
1026
00:56:01.619 --> 00:56:04.780
Several of my colleagues. And it helps with the vasculature,
1027
00:56:04.820 --> 00:56:07.860
the lining help control all the aspects of it. It
1028
00:56:07.900 --> 00:56:11.190
works really well. It's another one that works well. Another
1029
00:56:11.230 --> 00:56:15.159
big one that I think is really important I would
1030
00:56:15.199 --> 00:56:17.860
have to say is, you know, some people are naysayers.
1031
00:56:18.019 --> 00:56:20.219
I like vitamin C because I don't think you get
1032
00:56:20.280 --> 00:56:21.760
enough of it. If you can get it naturally, then
1033
00:56:21.800 --> 00:56:24.210
it's way better. Yeah. Go with that type of approach.
1034
00:56:24.429 --> 00:56:26.750
It's really good for you. What are other ones I take?
1035
00:56:27.130 --> 00:56:29.130
Some people don't like it, but if you can get
1036
00:56:29.170 --> 00:56:32.630
a good omega-3, I'm all about taking omegas. You have
1037
00:56:32.650 --> 00:56:35.420
to be careful. A lot of them are rancid. Yeah.
1038
00:56:36.050 --> 00:56:38.320
I'm really a SEPA dude, so I have it covered
1039
00:56:38.380 --> 00:56:40.079
on my end. Yeah, so you got it.
1040
00:56:40.079 --> 00:56:42.800
Yeah, correct. I'm a big taker. I take them too.
1041
00:56:43.019 --> 00:56:45.400
I use a specific brand that I like that I
1042
00:56:45.440 --> 00:56:47.400
know is not rancid. It doesn't cause any gut issues.
1043
00:56:48.000 --> 00:56:49.800
If you're taking something and you're burping it up, you
1044
00:56:49.820 --> 00:56:52.670
shouldn't be taking it. No, no. You shouldn't be taking it.
1045
00:56:52.800 --> 00:56:55.449
And then what are some of the other ones that...
1046
00:56:55.409 --> 00:56:57.510
Anything cellular-wise that you recommend?
1047
00:56:57.949 --> 00:57:00.670
Like I brought up urolithin A or senolytics or anything
1048
00:57:00.690 --> 00:57:02.250
like that or anything that you recommend.
1049
00:57:02.690 --> 00:57:05.300
I just go with food. with that for me. I
1050
00:57:05.340 --> 00:57:08.500
go with food, with anything like that. I think important
1051
00:57:08.559 --> 00:57:12.139
foods that you want to take for immune function, you know,
1052
00:57:12.179 --> 00:57:14.119
one of the good ones is actually great is colostrum
1053
00:57:14.280 --> 00:57:16.889
and not enough people take it or do anything with it.
1054
00:57:16.889 --> 00:57:19.150
I'm glad you brought that up. It helps increase natural
1055
00:57:19.170 --> 00:57:22.690
killer cell activity. That's proven. Like we said, we talked
1056
00:57:22.710 --> 00:57:26.309
about yogurts. Anything that deals with helping the gut And
1057
00:57:26.369 --> 00:57:29.739
absorption is key. I eat a shitload of Greek yogurt,
1058
00:57:29.780 --> 00:57:31.760
so that's a good thing. So do I now. I
1059
00:57:31.780 --> 00:57:33.159
do too a lot. Full fat.
1060
00:57:33.219 --> 00:57:35.860
You know how many years I ate low-fat Greek yogurt
1061
00:57:35.900 --> 00:57:38.219
and just ruined it? And not only does it taste
1062
00:57:38.260 --> 00:57:40.760
like shit, but it's stripped of everything that you need.
1063
00:57:40.780 --> 00:57:41.239
You need, yeah.
1064
00:57:41.530 --> 00:57:41.800
Yeah.
1065
00:57:42.260 --> 00:57:43.670
No, I love that.
1066
00:57:43.789 --> 00:57:46.349
And it seems like that pops up in everything and
1067
00:57:46.429 --> 00:57:49.650
everybody I ever talk to that comes on here. Yogurt's
1068
00:57:49.710 --> 00:57:52.349
brought up every rip when I talk about something that
1069
00:57:52.389 --> 00:57:53.170
we're eating for health.
1070
00:57:53.429 --> 00:57:56.570
Yep. In some way, especially when it relates to the gut. Yep. Yeah.
1071
00:57:56.670 --> 00:57:58.889
It works fantastic. I love it. That was good. It
1072
00:57:58.929 --> 00:58:00.650
makes you feel good. It's a great way to start.
1073
00:58:01.210 --> 00:58:02.570
It's a great way actually to start your day and
1074
00:58:02.610 --> 00:58:04.690
end your day. If you want something, you know what,
1075
00:58:04.730 --> 00:58:07.699
if you, if you want your something sweet, throw some
1076
00:58:07.739 --> 00:58:09.579
berries in it and have it at night. Like whatever,
1077
00:58:09.599 --> 00:58:12.340
if you have that sweet craving, you know, throw some
1078
00:58:12.360 --> 00:58:13.610
berries in it and go for it.
1079
00:58:14.019 --> 00:58:16.159
You know why I'm laughing? Cause you know what I
1080
00:58:16.199 --> 00:58:18.480
do every day when I stopped eating at night, first
1081
00:58:18.500 --> 00:58:20.019
thing in the morning before I go for a walk,
1082
00:58:20.039 --> 00:58:22.489
cause I don't eat breakfast. I have a, like a
1083
00:58:22.610 --> 00:58:24.929
half a serving of Greek yogurt and it has some
1084
00:58:24.989 --> 00:58:27.170
blueberries in it with a little protein powder. And that's
1085
00:58:27.230 --> 00:58:28.730
the last thing I have before I go to bed.
1086
00:58:29.050 --> 00:58:31.389
Yep. Every night. And you'll sleep better too. I do.
1087
00:58:32.110 --> 00:58:33.769
Because you've got some carbs in there that help you
1088
00:58:33.789 --> 00:58:34.710
sleep better.
1089
00:58:34.750 --> 00:58:35.210
Yep. Yep.
1090
00:58:35.409 --> 00:58:37.480
That's awesome. I love it.
1091
00:58:37.989 --> 00:58:41.050
Well, it's a personal invite to come back because we
1092
00:58:41.070 --> 00:58:43.449
didn't get through a fraction of what I wanted, but
1093
00:58:43.670 --> 00:58:46.349
when they're this good, you don't. the invite is there.
1094
00:58:46.409 --> 00:58:47.969
I hope you'll come back. Absolutely.
1095
00:58:48.590 --> 00:58:49.409
Come back out this way.
1096
00:58:49.809 --> 00:58:51.860
I knew, and I told you this before we started,
1097
00:58:51.920 --> 00:58:53.920
I was really excited to talk to you. And I
1098
00:58:53.980 --> 00:58:55.780
said that in the car right here, my wife can
1099
00:58:55.820 --> 00:58:57.699
attest to that. And this was even better than I
1100
00:58:57.760 --> 00:58:58.579
expected it to be.
1101
00:58:58.980 --> 00:59:01.659
Awesome. Thank you. Pleasure and honor to be here and
1102
00:59:02.139 --> 00:59:05.710
grateful to actually be here because you have to be grateful.
1103
00:59:05.789 --> 00:59:08.619
People do not understand when you're driving down the street
1104
00:59:09.119 --> 00:59:11.320
and you think you have it bad, look at somebody
1105
00:59:11.440 --> 00:59:15.099
else and see how bad they might have it. Understand.
1106
00:59:15.139 --> 00:59:18.659
I tell my kids on a daily basis, stay blessed,
1107
00:59:19.099 --> 00:59:21.320
be blessed. And if you think things are bad for you,
1108
00:59:22.320 --> 00:59:26.389
look around you and be grateful for what you have to,
1109
00:59:26.809 --> 00:59:29.610
you have to have that, that mindset. I want to
1110
00:59:29.630 --> 00:59:30.730
say this in closing.
1111
00:59:30.909 --> 00:59:33.889
And I say this, I have come to the practice
1112
00:59:34.150 --> 00:59:37.039
to thank God when I leave the gym, because it's a,
1113
00:59:37.510 --> 00:59:38.969
it's a grace to be able to work out and
1114
00:59:38.989 --> 00:59:40.750
do what I love to do, or to sometimes when
1115
00:59:40.769 --> 00:59:42.550
I just leave the store or something, because I was
1116
00:59:42.570 --> 00:59:44.760
able to buy the stuff that we needed and the
1117
00:59:44.840 --> 00:59:46.929
things that you take for granted every single day that
1118
00:59:46.969 --> 00:59:50.199
you don't realize until you get sick or something that
1119
00:59:50.260 --> 00:59:52.500
comes up and you can't go do it, how it
1120
00:59:52.559 --> 00:59:55.110
sucks so bad without it. You should be thankful for
1121
00:59:55.130 --> 00:59:58.090
the littlest of smallest things because those accumulate into what
1122
00:59:58.110 --> 00:59:59.869
you do every single day into your whole life. And
1123
00:59:59.909 --> 01:00:01.849
if you can't be grateful for the little things, then
1124
01:00:01.869 --> 01:00:03.010
you just don't deserve anything.
1125
01:00:03.030 --> 01:00:06.420
Yeah, I agree. You just don't. So thank you, Dr. Pompa,
1126
01:00:06.440 --> 01:00:08.480
for the introduction. Thanks to my doctor.
1127
01:00:09.300 --> 01:00:11.440
Tell everybody where to follow you, where to find you
1128
01:00:11.559 --> 01:00:13.460
and link it all in the description.
1129
01:00:13.880 --> 01:00:16.059
I mean, you can check me out on my Instagram,
1130
01:00:16.099 --> 01:00:20.880
which is DrGonzalezPhD, Restem.com. You can actually have a look
1131
01:00:20.940 --> 01:00:24.650
at us and then also ReHealth.com. is one of our
1132
01:00:24.769 --> 01:00:27.010
ex-US entities. Excellent.
1133
01:00:27.090 --> 01:00:29.789
Like I said, this was freaking awesome. And I really
1134
01:00:29.829 --> 01:00:32.789
enjoyed this to the highest extent. So thanks for coming.
1135
01:00:33.550 --> 01:00:35.860
And that wraps up another one, everybody. I hope that
1136
01:00:35.889 --> 01:00:37.860
you take a ton from this. We're going to come
1137
01:00:37.900 --> 01:00:40.559
back for another part two and maybe part three, who knows?
1138
01:00:40.679 --> 01:00:43.500
So that being said, stay tuned for plenty more to come.
1139
01:00:43.760 --> 01:00:45.639
Dylan Gemelli, signing off.