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Dr. Alfonso Fasano is a leading neurologist and researcher specializing in Parkinson’s disease, deep brain stimulation (DBS), neuromodulation, and freezing of gait. His work has contributed to advancing our understanding of Parkinson’s and the development of new approaches to treatment, including adaptive DBS.
In this episode, he joins Gaia to explore how advances in Parkinson’s treatment can translate into better movement, greater independence, and improved quality of life.
They discuss the latest developments in adaptive DBS, who may benefit from brain stimulation, and why even the most advanced technologies have limitations. They also explore the science behind freezing of gait, the complexities of neuroplasticity, and common misconceptions about levodopa and dyskinesia.
Throughout the conversation, Dr. Fasano emphasizes that treatment is not simply about reducing symptoms. It is about creating opportunities to exercise, remain socially engaged, and continue doing the things that make life meaningful. He also shares powerful reflections from people who have lived with Parkinson’s for more than 30 years.
WHAT WE COVER:
• How adaptive DBS differs from traditional DBS• What adaptive DBS can and cannot improve• Who may be a good candidate for DBS• Why patient expectations matter before surgery• Why DBS is not a cure for Parkinson’s• The limitations of DBS and why it cannot eliminate all motor symptoms• How brain activity and beta waves relate to Parkinson’s symptoms• Why neuroplasticity is not always beneficial• The science behind freezing of gait• How multitasking and cognitive demands affect walking• Levodopa, dyskinesia, and common medication misconceptions• Why delaying medication can sometimes reduce quality of life• When Parkinson’s medication may be necessary• Why treatment adjustments require time and communication• The importance of trust between patients and neurologists• Why exercise and social engagement matter alongside medical treatment• The role of family and caregivers in DBS outcomes• Insights from Reprogramming My Brain, co-authored with Benjamin Stecher• What people living with Parkinson’s for over 30 years would tell their newly diagnosed selves
WHAT’S NEXT:
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