WEBVTT
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Welcome to Flight Path, the podcast where we explore the journeys behind bold leadership, innovation, and lasting impact.
00:00:10.960 --> 00:00:19.839
Each episode we sit down with leaders, innovators, and rule breakers who build their success by doing the work, learning the lessons, and sometimes ignoring the map altogether.
00:00:20.000 --> 00:00:29.280
Whether you're navigating leadership, healthcare, technology, entrepreneurship, or simply trying to figure out what's next without losing your mind, you're at the right place.
00:00:29.519 --> 00:00:32.960
Before we take flight, we'd like to thank our sponsor, EFAX.
00:00:33.280 --> 00:00:37.759
Helping businesses and professionals stay connected with a secure, convenient document chair.
00:00:38.240 --> 00:00:40.000
Facts online with eFax.
00:00:40.240 --> 00:00:41.600
Now fasten your seatbelt.
00:00:41.840 --> 00:00:47.840
Adjust your altitude and get ready for stories, insights, and conversations that just might change your course.
00:00:48.079 --> 00:00:49.039
Welcome aboard.
00:00:49.200 --> 00:00:50.799
This is Flight Path.
00:00:51.039 --> 00:00:54.799
Hey everyone, and welcome to another episode of Flight Path.
00:00:54.960 --> 00:01:00.960
We are taking our flight to health this year, um, just in uh less than a month.
00:01:01.119 --> 00:01:09.439
And we're super excited to have Noelle on the podcast today to tell us about inflection medicine, which will be at health.
00:01:09.519 --> 00:01:11.439
And I can't wait to meet you in person.
00:01:11.519 --> 00:01:14.079
Um I give tackle hugs, so I hope you're ready.
00:01:14.319 --> 00:01:19.040
Um, why don't you tell us a little bit about yourself and what you all do?
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Yeah, thanks, Rebecca, and thank you for having me on.
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I'm so excited to be chatting with you and talking about inflection and health.
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Um, I love that we're all going to be there.
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And uh I look forward to the hug.
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I also am a hugger, so no problems there.
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Um a little bit about myself.
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I lead the commercial team at Inflection Medicines.
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So my team is responsible for finding, onboarding, and supporting our health system partnerships.
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Um, and what we do at Inflection is we are building the software operating layer to support genome-guided care uh in health systems.
00:02:02.400 --> 00:02:10.319
As you may know, this you know, precision medicine, genomic medicine thing is really taking off right now.
00:02:10.560 --> 00:02:15.759
And one thing we hear all the time is that it's a great idea.
00:02:16.000 --> 00:02:21.919
We want to have this big robust program, but we don't know how to turn it on and scale it.
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Uh, so that's what we built to solve.
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Okay.
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And so what does it do if if if a hospital comes to you and says they want to utilize you, how would they install it?
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And what would be the what would be the process?
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Yeah.
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So we've made it really easy.
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We do have a web-based version that we can turn on the same day that gets you many features, um, but it's definitely meant to be a first step.
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Uh, and then we can do a full EHR integration in as little as six weeks.
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And that's from, you know, first conversation to fully operational uh after testing.
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Obviously, sometimes contracting and some of those things can extend that six weeks.
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Um, but it's it's pretty easy to get going with us, and we're built to support everything from identifying the right patients who qualify for testing based on institutional criteria.
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We don't define that, the system does.
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Um, easy ordering and resulting workflow.
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And then one thing we do that's very unique in this space is we offer uh genomic clinical guidance, uh, which is something that's offered in some parts of precision medicine, but not all of them.
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And we kind of bridge that gap.
00:03:38.479 --> 00:03:43.919
Um, and then we also can follow that patient throughout the lifetime.
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Uh, and this is becomes a living record that the clinician can come back to and consult uh anytime new symptoms arise.
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So are you finding yourself more on the research side still, or are you going over into patient care as well?
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You know, there's definitely a big research component, but we are really pushing forward the uh the clinical side.
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Um, and luckily we've got a couple great partners who are helping us push that ahead in their systems.
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Um, because like you said, in many of these, they're still kind of stuck in research and how do we get it out and get it to more patients?
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Um I mean, I so this is super exciting to me.
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And I just have been like preaching that this is coming.
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And I know everybody's worried about their, you know, their testing and everything being out there in public and security and all of that.
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But all that aside, like I just got my genomic testing done because I have a natural path that uh her name's Margaret Paquette, she's come on my stages before.
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Um, but got that done and she helped me evaluate it and like what I should be doing, right?
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And then I was so interested and so loud that I actually got my children done.
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And so, like, imagine having their genetic testing done at 11 and 13 and knowing what you should avoid or knowing what could be coming.
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So don't do this or that.
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Um, at 11, like I really think this is just such a game changer for patients to move to welfare instead of this disgusting sick care model that we're in.
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Um, and I mean, I feel better because of that, because we ran those tests, because now I know what to avoid or or or what supplements to have or whatever.
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And um, yeah, you guys are a game changer.
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Game changer.
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And I still think people are so how are you helping people come over that fear, right?
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Because I'm not scared, but people in my family are like, you did that?
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Why would you do that?
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Right?
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Like, how are you helping those people?
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Yeah, and I think, you know, of course people are scared, right?
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It's a it's a big deal.
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And there's been some actors in the space that haven't been great stewards of that information.
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Um, so our biggest thing is the patient and the families always own access to their care.
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So we actually have a family app.
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The patients can go in.
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We will never share the information without explicit consent from the family.
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And if they give consent, they can pull that back anytime.
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And um, you know, it's not like a big like, oh, can we share your information?
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Yes or no.
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It's by group.
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And I think especially in in rare disease where a lot of this is being done right now, um, there is interest in more information sharing because one thing we can connect them with, we can connect them with like biopharma partnerships and make sure that they're getting in the right clinical trials and that kind of thing.
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Um, but patient ownership is very important to us.
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Um, and I think the family app is kind of the unlock to that, right?
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Like you don't have to call us and talk to a support person to know where your information is going.
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You can log into a web page and say yes or no.
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Yeah.
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Yeah.
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I mean, I think we need to move more towards patient first and then as as nervous, right?
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So are you coming to Cambridge a lot?
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Because we have tons of pharma in my on my side of the United States because you're all the way over in Seattle.
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Yeah.
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So Inflection's actually based in Boston.
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So I'm there once a month.
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Um yeah.
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So we've got to find time for you to take a train in and we'll get together.
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Um, but yeah, there's there's a ton of biopharma um there.
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And a lot of our investors are in Boston.
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So we're in that ecosystem pretty heavily, and it's a great ecosystem to be a part of.
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Um, just like the idea sharing and you know, the amount of times we can say, oh, well, I know someone that's kind of working on this.
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Why don't we set up a call and see how we can collaborate?
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It's a really great place to be for sure.
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How did you get involved in all of this?
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What was sort of your undergrad?
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Did you fall into it?
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Or you were like, I'm gonna go straight to genes right out of college.
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Yeah.
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Uh that was definitely not my path.
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I actually majored in political science.
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Um, so very different.
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Uh, and then eventually got into healthcare sales, and that's you know, kind of my path toward this.
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Um for a while I was doing rare disease pharma sales, and that's how I kind of backdoored into genomics.
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Okay.
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Um, you know, for rare disease, one of the biggest challenges is you have to get a diagnosis before you can be treated.
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And for a lot of these, they're genetic.
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So you need access to high-quality genetic testing to even end that diagnostic odyssey these patients go on.
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Um, so from the rare disease pharma, I went to a sequencing lab uh that was doing whole genome sequencing.
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I was in another commercial leadership role there.
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Um, and then when I found out what inflection was doing, I was like, this solves the problem I keep hearing about.
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Um and so luckily had the opportunity to join this team.
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And it's really fun.
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It's really fun being able to go in and say, like, you know, that thing we talked about a couple of years ago, and you know, you didn't know how to overcome it.
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Like, here you go.
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I have a solution.
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I love that.
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I love I journal, I journal.
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I don't know if you journal until like I actually just went back in my book yesterday and I was like, it's happening.
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That that what I wrote, I manifested, that's happening.
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I love it.
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Have you been to health before?
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I have not.
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So this will be my first time and reflection's first time.
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Yes, I'm so excited.
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Okay, so do you guys have a booth?
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Are you walking around?
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What's your approach?
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Yep, we have a booth in the AI zone.
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So I'm very excited about that.
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I don't yet, but I will let you know.
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Um you know, we we might have the number somewhere.
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Uh, I apologize to everyone at health if you have assigned it to me and you're hearing this.
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Um but we're really excited.
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We've got uh our chief genomics officer and one of our clinical champions from Mayo Clinic are doing a presentation on what we're standing up at Mayo, which I think is going to be really interesting.
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Um, but you know, health obviously, as as you know, you're going to, right?
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It's the place where folks really get together to talk about what's next, what's innovative, what's coming, and then cultivate those partnerships.
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So I'm really looking forward to those conversations.
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That's what I'm I'm excited about.
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I mean, I go to all of the other big conferences, but this one's really drives innovation.
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Um, and you'll walk by a lot of boots and you're like, okay, I don't really actually see that working right.
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But then there's others that are gonna make it, right?
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I mean, that's the whole startup process, right?
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Um there's others that are gonna make it and they're just gonna really change healthcare and for the patient like you were all born.
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So we're super excited to see you at health.
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Um, we're bringing our cameras and our our uh video cameras, so maybe we can do some live uh live videoing there.
00:10:56.720 --> 00:11:05.279
Um, but yeah, thanks for jumping on uh Flight Path and we will take on health for the first time together next month.
00:11:05.600 --> 00:11:06.159
Can't wait.
00:11:06.320 --> 00:11:07.279
Sounds good, Rebecca.
00:11:07.360 --> 00:11:08.159
Thank you.
00:00:04.080 --> 00:00:10.800
Welcome to Flight Path, the podcast where we explore the journeys behind bold leadership, innovation, and lasting impact.
00:00:10.960 --> 00:00:19.839
Each episode we sit down with leaders, innovators, and rule breakers who build their success by doing the work, learning the lessons, and sometimes ignoring the map altogether.
00:00:20.000 --> 00:00:29.280
Whether you're navigating leadership, healthcare, technology, entrepreneurship, or simply trying to figure out what's next without losing your mind, you're at the right place.
00:00:29.519 --> 00:00:32.960
Before we take flight, we'd like to thank our sponsor, EFAX.
00:00:33.280 --> 00:00:37.759
Helping businesses and professionals stay connected with a secure, convenient document chair.
00:00:38.240 --> 00:00:40.000
Facts online with eFax.
00:00:40.240 --> 00:00:41.600
Now fasten your seatbelt.
00:00:41.840 --> 00:00:47.840
Adjust your altitude and get ready for stories, insights, and conversations that just might change your course.
00:00:48.079 --> 00:00:49.039
Welcome aboard.
00:00:49.200 --> 00:00:50.799
This is Flight Path.
00:00:51.039 --> 00:00:54.799
Hey everyone, and welcome to another episode of Flight Path.
00:00:54.960 --> 00:01:00.960
We are taking our flight to health this year, um, just in uh less than a month.
00:01:01.119 --> 00:01:09.439
And we're super excited to have Noelle on the podcast today to tell us about inflection medicine, which will be at health.
00:01:09.519 --> 00:01:11.439
And I can't wait to meet you in person.
00:01:11.519 --> 00:01:14.079
Um I give tackle hugs, so I hope you're ready.
00:01:14.319 --> 00:01:19.040
Um, why don't you tell us a little bit about yourself and what you all do?
00:01:19.680 --> 00:01:22.640
Yeah, thanks, Rebecca, and thank you for having me on.
00:01:22.719 --> 00:01:28.000
I'm so excited to be chatting with you and talking about inflection and health.
00:01:28.159 --> 00:01:30.480
Um, I love that we're all going to be there.
00:01:30.719 --> 00:01:32.879
And uh I look forward to the hug.
00:01:32.959 --> 00:01:36.000
I also am a hugger, so no problems there.
00:01:36.239 --> 00:01:38.560
Um a little bit about myself.
00:01:38.879 --> 00:01:41.920
I lead the commercial team at Inflection Medicines.
00:01:42.000 --> 00:01:49.120
So my team is responsible for finding, onboarding, and supporting our health system partnerships.
00:01:49.359 --> 00:02:02.079
Um, and what we do at Inflection is we are building the software operating layer to support genome-guided care uh in health systems.
00:02:02.400 --> 00:02:10.319
As you may know, this you know, precision medicine, genomic medicine thing is really taking off right now.
00:02:10.560 --> 00:02:15.759
And one thing we hear all the time is that it's a great idea.
00:02:16.000 --> 00:02:21.919
We want to have this big robust program, but we don't know how to turn it on and scale it.
00:02:22.000 --> 00:02:24.560
Uh, so that's what we built to solve.
00:02:24.879 --> 00:02:25.120
Okay.
00:02:25.280 --> 00:02:32.879
And so what does it do if if if a hospital comes to you and says they want to utilize you, how would they install it?
00:02:33.039 --> 00:02:35.680
And what would be the what would be the process?
00:02:36.000 --> 00:02:36.479
Yeah.
00:02:36.800 --> 00:02:38.800
So we've made it really easy.
00:02:38.960 --> 00:02:49.199
We do have a web-based version that we can turn on the same day that gets you many features, um, but it's definitely meant to be a first step.
00:02:49.280 --> 00:02:54.400
Uh, and then we can do a full EHR integration in as little as six weeks.
00:02:54.560 --> 00:03:01.199
And that's from, you know, first conversation to fully operational uh after testing.
00:03:01.360 --> 00:03:06.319
Obviously, sometimes contracting and some of those things can extend that six weeks.
00:03:06.479 --> 00:03:18.479
Um, but it's it's pretty easy to get going with us, and we're built to support everything from identifying the right patients who qualify for testing based on institutional criteria.
00:03:18.639 --> 00:03:20.879
We don't define that, the system does.
00:03:21.039 --> 00:03:24.000
Um, easy ordering and resulting workflow.
00:03:24.240 --> 00:03:36.319
And then one thing we do that's very unique in this space is we offer uh genomic clinical guidance, uh, which is something that's offered in some parts of precision medicine, but not all of them.
00:03:36.400 --> 00:03:38.319
And we kind of bridge that gap.
00:03:38.479 --> 00:03:43.919
Um, and then we also can follow that patient throughout the lifetime.
00:03:44.000 --> 00:03:52.000
Uh, and this is becomes a living record that the clinician can come back to and consult uh anytime new symptoms arise.
00:03:52.319 --> 00:04:00.080
So are you finding yourself more on the research side still, or are you going over into patient care as well?
00:04:00.879 --> 00:04:09.759
You know, there's definitely a big research component, but we are really pushing forward the uh the clinical side.
00:04:09.919 --> 00:04:16.800
Um, and luckily we've got a couple great partners who are helping us push that ahead in their systems.
00:04:16.879 --> 00:04:23.680
Um, because like you said, in many of these, they're still kind of stuck in research and how do we get it out and get it to more patients?
00:04:23.839 --> 00:04:27.040
Um I mean, I so this is super exciting to me.
00:04:27.120 --> 00:04:30.480
And I just have been like preaching that this is coming.
00:04:30.560 --> 00:04:37.680
And I know everybody's worried about their, you know, their testing and everything being out there in public and security and all of that.
00:04:37.839 --> 00:04:46.800
But all that aside, like I just got my genomic testing done because I have a natural path that uh her name's Margaret Paquette, she's come on my stages before.
00:04:46.879 --> 00:04:52.240
Um, but got that done and she helped me evaluate it and like what I should be doing, right?
00:04:52.399 --> 00:04:56.480
And then I was so interested and so loud that I actually got my children done.
00:04:56.639 --> 00:05:04.480
And so, like, imagine having their genetic testing done at 11 and 13 and knowing what you should avoid or knowing what could be coming.
00:05:04.560 --> 00:05:06.319
So don't do this or that.
00:05:06.480 --> 00:05:17.360
Um, at 11, like I really think this is just such a game changer for patients to move to welfare instead of this disgusting sick care model that we're in.
00:05:17.600 --> 00:05:28.000
Um, and I mean, I feel better because of that, because we ran those tests, because now I know what to avoid or or or what supplements to have or whatever.
00:05:28.160 --> 00:05:30.959
And um, yeah, you guys are a game changer.
00:05:31.199 --> 00:05:31.839
Game changer.
00:05:31.920 --> 00:05:36.000
And I still think people are so how are you helping people come over that fear, right?
00:05:36.160 --> 00:05:39.519
Because I'm not scared, but people in my family are like, you did that?
00:05:39.600 --> 00:05:40.399
Why would you do that?
00:05:40.560 --> 00:05:40.720
Right?
00:05:40.800 --> 00:05:42.639
Like, how are you helping those people?
00:05:42.879 --> 00:05:45.920
Yeah, and I think, you know, of course people are scared, right?
00:05:46.000 --> 00:05:47.040
It's a it's a big deal.
00:05:47.199 --> 00:05:53.360
And there's been some actors in the space that haven't been great stewards of that information.
00:05:53.439 --> 00:05:58.959
Um, so our biggest thing is the patient and the families always own access to their care.
00:05:59.199 --> 00:06:01.120
So we actually have a family app.
00:06:01.360 --> 00:06:02.720
The patients can go in.
00:06:02.959 --> 00:06:07.600
We will never share the information without explicit consent from the family.
00:06:07.759 --> 00:06:10.879
And if they give consent, they can pull that back anytime.
00:06:11.120 --> 00:06:16.720
And um, you know, it's not like a big like, oh, can we share your information?
00:06:16.879 --> 00:06:17.600
Yes or no.
00:06:17.759 --> 00:06:18.959
It's by group.
00:06:19.040 --> 00:06:36.399
And I think especially in in rare disease where a lot of this is being done right now, um, there is interest in more information sharing because one thing we can connect them with, we can connect them with like biopharma partnerships and make sure that they're getting in the right clinical trials and that kind of thing.
00:06:36.560 --> 00:06:41.199
Um, but patient ownership is very important to us.
00:06:41.360 --> 00:06:45.199
Um, and I think the family app is kind of the unlock to that, right?
00:06:45.279 --> 00:06:51.120
Like you don't have to call us and talk to a support person to know where your information is going.
00:06:51.279 --> 00:06:54.480
You can log into a web page and say yes or no.
00:06:54.800 --> 00:06:55.040
Yeah.
00:06:55.199 --> 00:06:55.519
Yeah.
00:06:55.600 --> 00:07:01.040
I mean, I think we need to move more towards patient first and then as as nervous, right?
00:07:01.199 --> 00:07:02.879
So are you coming to Cambridge a lot?
00:07:02.959 --> 00:07:09.600
Because we have tons of pharma in my on my side of the United States because you're all the way over in Seattle.
00:07:09.839 --> 00:07:10.160
Yeah.
00:07:10.240 --> 00:07:12.399
So Inflection's actually based in Boston.
00:07:12.480 --> 00:07:14.079
So I'm there once a month.
00:07:14.319 --> 00:07:16.079
Um yeah.
00:07:16.319 --> 00:07:20.399
So we've got to find time for you to take a train in and we'll get together.
00:07:21.120 --> 00:07:26.079
Um, but yeah, there's there's a ton of biopharma um there.
00:07:26.160 --> 00:07:29.199
And a lot of our investors are in Boston.
00:07:29.279 --> 00:07:34.560
So we're in that ecosystem pretty heavily, and it's a great ecosystem to be a part of.
00:07:34.639 --> 00:07:42.160
Um, just like the idea sharing and you know, the amount of times we can say, oh, well, I know someone that's kind of working on this.
00:07:42.240 --> 00:07:44.720
Why don't we set up a call and see how we can collaborate?
00:07:44.879 --> 00:07:46.959
It's a really great place to be for sure.
00:07:47.279 --> 00:07:49.040
How did you get involved in all of this?
00:07:49.120 --> 00:07:50.800
What was sort of your undergrad?
00:07:50.879 --> 00:07:51.839
Did you fall into it?
00:07:51.920 --> 00:07:55.920
Or you were like, I'm gonna go straight to genes right out of college.
00:07:56.079 --> 00:07:56.399
Yeah.
00:07:56.879 --> 00:07:59.199
Uh that was definitely not my path.
00:07:59.279 --> 00:08:01.519
I actually majored in political science.
00:08:02.000 --> 00:08:04.079
Um, so very different.
00:08:04.319 --> 00:08:10.879
Uh, and then eventually got into healthcare sales, and that's you know, kind of my path toward this.
00:08:11.120 --> 00:08:19.360
Um for a while I was doing rare disease pharma sales, and that's how I kind of backdoored into genomics.
00:08:19.519 --> 00:08:19.759
Okay.
00:08:20.000 --> 00:08:28.319
Um, you know, for rare disease, one of the biggest challenges is you have to get a diagnosis before you can be treated.
00:08:28.639 --> 00:08:31.279
And for a lot of these, they're genetic.
00:08:31.439 --> 00:08:38.960
So you need access to high-quality genetic testing to even end that diagnostic odyssey these patients go on.
00:08:39.200 --> 00:08:47.360
Um, so from the rare disease pharma, I went to a sequencing lab uh that was doing whole genome sequencing.
00:08:47.519 --> 00:08:50.240
I was in another commercial leadership role there.
00:08:50.399 --> 00:08:57.039
Um, and then when I found out what inflection was doing, I was like, this solves the problem I keep hearing about.
00:08:57.519 --> 00:09:01.440
Um and so luckily had the opportunity to join this team.
00:09:01.679 --> 00:09:03.120
And it's really fun.
00:09:03.279 --> 00:09:10.879
It's really fun being able to go in and say, like, you know, that thing we talked about a couple of years ago, and you know, you didn't know how to overcome it.
00:09:11.039 --> 00:09:11.840
Like, here you go.
00:09:11.919 --> 00:09:12.879
I have a solution.
00:09:13.759 --> 00:09:14.159
I love that.
00:09:14.240 --> 00:09:15.519
I love I journal, I journal.
00:09:15.600 --> 00:09:20.720
I don't know if you journal until like I actually just went back in my book yesterday and I was like, it's happening.
00:09:20.799 --> 00:09:23.600
That that what I wrote, I manifested, that's happening.
00:09:23.840 --> 00:09:24.960
I love it.
00:09:25.200 --> 00:09:27.039
Have you been to health before?
00:09:27.360 --> 00:09:28.000
I have not.
00:09:28.159 --> 00:09:31.519
So this will be my first time and reflection's first time.
00:09:31.679 --> 00:09:33.039
Yes, I'm so excited.
00:09:33.279 --> 00:09:34.720
Okay, so do you guys have a booth?
00:09:34.799 --> 00:09:35.679
Are you walking around?
00:09:35.759 --> 00:09:36.639
What's your approach?
00:09:36.960 --> 00:09:39.279
Yep, we have a booth in the AI zone.
00:09:39.519 --> 00:09:41.440
So I'm very excited about that.
00:09:41.600 --> 00:09:43.600
I don't yet, but I will let you know.
00:09:44.080 --> 00:09:48.399
Um you know, we we might have the number somewhere.
00:09:48.480 --> 00:09:53.600
Uh, I apologize to everyone at health if you have assigned it to me and you're hearing this.
00:09:53.919 --> 00:09:55.919
Um but we're really excited.
00:09:56.080 --> 00:10:08.320
We've got uh our chief genomics officer and one of our clinical champions from Mayo Clinic are doing a presentation on what we're standing up at Mayo, which I think is going to be really interesting.
00:10:08.559 --> 00:10:12.879
Um, but you know, health obviously, as as you know, you're going to, right?
00:10:13.039 --> 00:10:20.080
It's the place where folks really get together to talk about what's next, what's innovative, what's coming, and then cultivate those partnerships.
00:10:20.320 --> 00:10:23.200
So I'm really looking forward to those conversations.
00:10:23.519 --> 00:10:25.120
That's what I'm I'm excited about.
00:10:25.279 --> 00:10:30.240
I mean, I go to all of the other big conferences, but this one's really drives innovation.
00:10:30.480 --> 00:10:35.440
Um, and you'll walk by a lot of boots and you're like, okay, I don't really actually see that working right.
00:10:35.600 --> 00:10:38.000
But then there's others that are gonna make it, right?
00:10:38.080 --> 00:10:39.919
I mean, that's the whole startup process, right?
00:10:40.240 --> 00:10:46.480
Um there's others that are gonna make it and they're just gonna really change healthcare and for the patient like you were all born.
00:10:46.720 --> 00:10:49.360
So we're super excited to see you at health.
00:10:49.440 --> 00:10:56.480
Um, we're bringing our cameras and our our uh video cameras, so maybe we can do some live uh live videoing there.
00:10:56.720 --> 00:11:05.279
Um, but yeah, thanks for jumping on uh Flight Path and we will take on health for the first time together next month.
00:11:05.600 --> 00:11:06.159
Can't wait.
00:11:06.320 --> 00:11:07.279
Sounds good, Rebecca.
00:11:07.360 --> 00:11:08.159
Thank you.
