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When you hear the word testosterone, I'm guessing the first word that comes to your mind probably isn't women's health Maybe it's men or muscle or libido, Or if you have spent five minutes on social media lately, you might think it's the hormone that's apparently going to fix your energy, motivation, sex drive, brain fog, muscle loss, and general enthusiasm for life And that is exactly why we need to talk about it.
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Women absolutely need testosterone We make testosterone naturally.
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It has important roles throughout our body.
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And for some women, testosterone therapy can be incredibly helpful But testosterone is also having a bit of a moment right now, and some of the claims being made about it have gotten ahead of the science So today I want to explain what testosterone actually does in women, what happens to it as we age, when testosterone therapy may be appropriate, and where the evidence isn't nearly as strong as social media would have you believe Before we get into it, for a little bit of context, I'm a physician assistant and I've been practicing for over 20 years, and I am going through this transition myself right now So when I talk about testosterone today, it's coming from both sides of the exam table.
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A little later in this video, I'm going to walk through exactly what this has looked like for me, including where we actually started with hormone replacement therapy and what we deliberately didn't start with Let's start with something surprising few women are ever taught.
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Testosterone is not a male hormone Men have significantly higher levels of testosterone, but women make testosterone too Before menopause, testosterone and other androgens come from both the ovaries and the adrenal glands, the little glands over your kidney And unlike estrogen and progesterone, testosterone doesn't suddenly fall off a cliff when you enter menopause Testosterone levels gradually decline with age.
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That's an important distinction because sometimes you'll hear that menopause causes testosterone deficiency That's not really an accurate way to describe what's happening We also don't have a clearly defined medical condition called female testosterone deficiency, where we can simply check a blood level and see that it's below a certain number and say,"There's the problem." Now, that doesn't mean that the number is meaningless.
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If your testosterone levels come back really low or on the low end of normal and you're dealing with symptoms that fit, that correlation matters.
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It is a piece of the picture that we need to take into account And that brings us to one of the most important things to understand about testosterone.
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A number on a lab report doesn't tell the whole story by itself Because if a testosterone level can't simply tell us whether a woman needs testosterone, how do we know when testosterone is actually part of the problem?
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Before we answer that, we need to understand what testosterone is doing in the first place testosterone is involved in sexual function, bone and muscle physiology, and multiple processes throughout the brain and the body This is where we have to separate two separate questions.
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Number one, what does testosterone do physiologically?
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And two, what have we actually proven testosterone therapy improves?
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Those are not necessarily the same thing, and that's really important We know testosterone is involved in muscle physiology, but that does not automatically mean giving additional testosterone to a midlife woman will build muscle or restore her strength We know androgens interact with the brain.
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That doesn't automatically mean testosterone therapy has been proven to treat brain fog, depression, or low motivation Where the evidence becomes much stronger is with sexual desire Testosterone plays an important role in sexual function, and testosterone therapy has evidence for certain women experiencing persistent low sexual desire that is causing significant distress There's actually a name for this.
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It's called hypoactive sexual desire disorder, or HSDD And no, that does not mean that every woman whose libido has disappeared somewhere between work and teenagers, poor sleep, vaginal discomfort, and the laundry pile has a testosterone deficiency Sexual desire is complicated.
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Hormones are one piece of that picture But they are not the only piece If you are enjoying this Understanding the Hormone series, I'd love for you to subscribe.
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My goal with these videos isn't to convince you that you need hormones or that you don't It is to give you enough information to understand your options and have a much better conversation with your healthcare provider Let's talk about why low libido isn't automatically low testosterone.
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This is probably the most important part of the conversation When women say that their libido has disappeared, there are a lot of things worth considering before assuming testosterone is the answer.
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Are you sleeping?
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Are you exhausted?
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Are you experiencing pain with sex?
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Has vaginal dryness made sex uncomfortable?
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Are medications affecting your sexual function?
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What's happening with your relationship?
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What's happening with stress?
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What are estrogen changes doing to your body?
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Because desire doesn't exist in a hormonal vacuum.
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Sometimes it disappears under the weakest thing in the room, not the biggest.
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The exhaustion that makes sex feel like one more task on a list that nobody's even grading you on.
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And there's another important piece.
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A low testosterone level by itself doesn't diagnose HSDD And a normal testosterone level doesn't necessarily tell us whether testosterone therapy could be helpful in an appropriately selected woman It doesn't mean that the lab is irrelevant.
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When a low or low normal number lines up with the right symptoms, that alignment is exactly what should guide the conversation.
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It's just never the number by itself.
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We need to look at the number and the symptoms and put those things together This is why the conversation has to start with the symptoms and context rather than simply chasing a lab number So if testosterone isn't something we simply replace because the lab says it's low, who actually might benefit from testosterone therapy?
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This is where the evidence becomes much narrower than a lot of social media would have you believe Right now, the strongest evidence for testosterone therapy in women is for that hypoactive sexual desire disorder, particularly in women after other contributors of low desire have been evaluated And this doesn't mean that researchers aren't studying testosterone for other things.
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They are and it doesn't mean that women aren't reporting improvements in energy, motivation, strength, and overall wellbeing.
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They do, but we just need more robust research to correlate it all personal experience and scientific evidence are not the same thing at this point, we do not have enough strong evidence to prescribe testosterone specifically to improve cognition, mood, energy, muscle mass, or general well-being in an otherwise healthy midlife woman And I think women need to know that distinction and you deserve to know that distinction because good perimenopause care isn't about being pro-hormone or anti-hormone.
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It's about understanding what we know and what we don't know yet and making an individualized decision from there I want to pause here and share my personal experience because I think it helps to hear how this actually plays out for a real woman, not just in theory And a quick caveat before I do this.
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This is my story.
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It's not a template.
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Your body, your history, your labs, they're going to tell a different story than mine did.
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This is exactly why the conversation with your own provider matters so much.
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No one else's timeline is yours.
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So for me, when I started working on my own perimenopause journey, we ran labs and my testosterone came back really low, but we didn't start replacing the testosterone.
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We started with estrogen and progesterone first, and we let those settle out before deciding what else was needed.
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Partly because sometimes bringing those hormones back into the range does some of the work on its own.
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Once things equilibrated for me, what was left was decreased desire and decreased energy.
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So that's when we made the decision to add testosterone in.
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Now for me, it has made an incredible difference.
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My desire has significantly improved.
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My husband is very thankful and grateful for this.
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But my energy has come back, and honestly, my confidence has come back with it and if I'm being honest, I probably could have used this testosterone boost 10 years earlier.
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But here we are, and that's part of why I wanted to make this video in the first place.
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This is a crazy ride.
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This perimenopausal phase, so much is going on, and we just need that information out there So let's talk about one of the problems that we're experiencing.
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There's another wrinkle here.
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In the United States, there is no currently FDA-approved testosterone product specifically formulated for women That means that clinicians who prescribe testosterone to women are generally using it off-label And because women need significantly smaller dosages than men, that dosing matters.
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More is absolutely not better There's different ways that this is being prescribed.
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There's compounding pharmacies that a lot of women are getting testosterone through.
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There are pellets, which I would advise against, and there is instances where women are being prescribed the medication meant for men and just dosing it down.
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Talk with your provider So going back to the more doesn't mean better, it matters because when you're desperate for relief, you might be tempted to think that more must be doing more.
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Unfortunately, too much of a good thing can cause problems, right?
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So too much testosterone can cause acne, increased facial hair or body hair, scalp hair thinning or other androgenic effects.
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That's also why monitoring matters The goal isn't to push testosterone as high as possible.
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It's to keep levels within physiologic range expected for women while assessing whether the symptoms we're experiencing are actually improving this is also why I'd be cautious about anyone selling testosterone as an anti-aging shortcut or promising that one hormone is gonna fix everything you're experiencing in midlife Hormones are powerful, and that's precisely why we deserve thoughtful use And there's one more reason why I don't think that testosterone should be the first hormone that we reach for.
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Sometimes the symptoms a woman attributes to testosterone are being driven by something else It could be poor sleep, hot flashes, vaginal discomfort, mood changes All of these can absolutely affect energy, motivation, sexual desire, and quality of life So before deciding that testosterone is the missing piece, it makes sense to look at the whole picture.
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What symptoms are actually bothering you?
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What else could be contributing?
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Are your estrogen-related symptoms adequately being addressed?
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Are medications or other health conditions playing a role?
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Before you choose one hormone, it's worth looking at the terrain that hormone is actually operating on.
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Because treating hormones isn't about replacing every number on a lab report until it looks like you're 25 again.
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It's about treating the woman sitting right in front of you If you remember one thing from today's video, let it be this.
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Testosterone matters in women It isn't just a male hormone and it isn't just about sex, but that also doesn't mean testosterone is the missing answer for every woman who feels tired, unmotivated, or different in midlife The science right now is strongest in one particular area, persistent, distressing low sexual desire in appropriately selected women For everything else, we're still learning, and I actually think that's an empowering place to be You don't need someone promising that testosterone will fix everything.
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You need good information, a clinician willing to look at the whole picture, and a treatment plan built around you rather than a specific number on a report next in our Understanding Hormone series, we're gonna tackle one of the most frustrating things that women hear during perimenopause.
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Your labs are normal normal hormone labs do not necessarily mean you aren't in perimenopause, and we are gonna talk about that and explain why Thanks again for watching, and I'll see you next time