WEBVTT
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Greetings and welcome to the United States Transhumanist Party Virtual
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Enlightenment Salon. My name is Jannati Stolier of the Second
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and I am the Chairman of the US Transhumanist Party.
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Here we hold conversations with some of the world's leading
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thinkers in longevity, science, technology, philosophy, and politics. Like the
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philosophers of the Age of Enlightenment, we aim to connect
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every field of human endeavor and arrive at new insights
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to achieve longer lives, greater rationality, and the progress of
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our civilization.
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Aging is a natural process, but it's a process which
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both our health and wealthy.
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We are lucky to have longevity researchers developing rejuvenation therapies.
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Welcome to Transvision twenty twenty five.
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Now let's move into a real investor.
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A real investor.
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You know, I have known Angel Versetti and what he
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has been doing with his family office and also Dodge
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dot org. And he has a lot of things to
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say about how big this industry is, what will happen
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in terms of investment possibilities, venture capital, and where we
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are going to go with the longevity industry.
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So let's welcome Angel.
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Thank you everyone, it's a pleasure to be here in
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the beautiful city of Madrid. So my presentation is titled
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some Candidate Raw thoughts on the state of longevity as
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an investment. So it's thoughts a lot of them and
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through the prism of our experience as an investor and
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their candidate, meaning that we want to be bullish, but
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then there are some challenges we need to acknowledge.
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So I decided to use the quote here.
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From a Spanish writer and philosopher, Miguel de Unamuno. I
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hope I'm pronouncing it correctly. That explains my style, which
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is minimalistic. I think post child GPT raight. Far too
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many fanciful designs out there, so I try to focus
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on the content and briefly about my journey. I'm a
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serial entrepreneur, having exited four different companies, two of them
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became unicorns in Web three and II domains. I also
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owned dosh dot org, which became the first online community
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for doshcoin, which became one of the most famous cryptocurrencies
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in the world.
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So I host the forum where the.
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First pictures of the dog were shared, and that would
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have been a joke, but that joke turned out to
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be nearly one hundred billion dollar market cap thing. So
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there was a nice joke, and as of this year,
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we've decided to focus entirely on longevity in terms of
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our new ventures. Although I have been in the community
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in various forms as an investor, grant making organization, and
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an entrepreneur for about five and a half years since
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the early days of COVID. So just a few clarifications,
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it's difficult for us to define what exactly we are
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because we're not really a VC. Here, you have some
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you know, what's scratched is what a typical VC is like,
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and what's written is what we have. So a venture
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capital fund will typically have money from limited partners as
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people who give money to the VC to invest. Therefore,
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their mandate tends to be fixed because when you promise
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someone to invest their money in a certain way, you
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kind of have to stick to your promise. A lot
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of VC funds have a particular timeline through which they
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have to return their money to the investors. That makes
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a lot of them sure to meetium term, and that
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is not a problem in many industries like software, but
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that is a problem for the space like longevity, which
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requires much longer timeframes of investment a lot of the
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funds that I have met.
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It's my opinion.
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I'm sure they will disagree, but I felt that they
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spray and pray, meaning that they invest in a bit
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of everything, but they don't have a particular like conviction bets,
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and they tend to source a lot of deals externally.
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In our case, the capital is our own, therefore the
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mandate is flexible.
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We can afford to be long term and we are.
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Happy to support radical moonshots that move the needle. And
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we also have the venture builder approach of which I
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will talk about later. So we're also not a typical
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family office, because family offices tend to be conservative and defensive.
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Their goal is to preserve their wealth rather than grow it.
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As a result, they tend to be diversified and passive allocators.
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In our case, we're entrepreneurial. We're happy to take risks,
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sometimes not too happy and when the results are not
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that great, but that's what we're in for. I guess
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we are focused on wealth growth for ourselves and for
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the industry generally. Therefore, we make concentrated bets, whereby we
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have a lot of skin game and we push the
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companies to really focus on being operationally viable and commercially viable,
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and we are a hands on operator, meaning that we
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like to be very actively involved with our investments. I
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would say around ninety to ninety five percent of family
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offices do not operate this way. Therefore, I'm not even
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sure if the name family office is correct for us.
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And when I started just researching longevity, I read a
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bunch of books by some of the most famous people
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in longevity, and if I were to summarize them in
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five small bullet points, most of them just said eat well, exercise,
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good sleep, no stress.
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No bad habits.
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And while I'm like, Okay, why do I need all
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these Harvard PhDs and Stanford professors and whatnot to really
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tell me what I knew since I was a kid,
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what my parents told me to do. Moreover, when I
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researched a be deeper into the history of longevity, there
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was an ancient Chinese philosopher and physician Gihong who said,
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even if one performs breathing exercises and strength training as
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well as in herbal medicines, this can only extend the
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years of your lifespan, but it will not save you
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from death, So that guy knew about it two thousand
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years ago, and we're still like just repeating the same stuff,
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and we're still struggling in the same way. Although of
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course my personal response to that is that thankfully today
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we have so many technological advancements so that hopefully we
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can move beyond pure wishful thinking. So general, my thesis
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is that longevity is hard. There are a number of
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reasons that we've identified through our research. Again, these are
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mostly opinions. I mean, there are many kind of anecdotal
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stories or specific backing them, but these are mostly my thoughts,
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so don't take them as facts. But it feels that
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their market is still immature and fragmented. People are still
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fighting about like what the definition of longevity should be.
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I know it was a big subject of discussion at
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this year's ARDD in Copenhagen. And therefore, if you don't
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have even the universally accepted definition, of course, is difficult
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for regulatory frameworks and standards to be developed, so they're
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either poorly developed or non existent. They feel this multi
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dimensional and highly complex, and I would say there are
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two big chunks of participants when I look at it
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from the business perspective. On the one side, there are
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I call them hypocrite hygh writers. These are businesses that
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don't really care about longevity, but they use the word
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because it's an attractive investment term. And on the other side,
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I mean, I call them like fanatic dreamers. They religiously
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believe in longevity, they believe in the necessary to radically
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increase lifespan and so on.
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But they are just like they're focused.
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On it like a religion, and you need to find
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some golden means, some middle ground, and then of course,
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I mean it's a no brainer. But biology itself is hard,
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and I say that as a non biology guy coming
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from a different background, and of course that's you know,
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there are many examples where it's not just easy to
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predict what's going to happen. So longevity startups are also hard.
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So when we extrapolate from that to startups in particular, that's.
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What we're focused on.
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So a lot of them have again that's you know,
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what our assessment is from our scientific and due diligence teams,
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but they frequently lack clinical depth on clinical guidelines diverge
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from country to country, so that's difficult for them to
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be comparable to each other. Of course, a lot of
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them have unsustainable margins and economics. We have observed a
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number of high profile failures where when we try to
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analyze what exactly did the team go wrong when the
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company went bankrupt, there was not like particular reason, It
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was not like an obvious failure or mistake, just the
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economics didn't work. There are cases of longevity clinics that failed,
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There are cases of companies that are biotech that failed,
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and a number of others. So the graveyard of startups
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in longevity is huge. A lot of startups engage in
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misleading marketing, which leads to low consumer trust when they
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make some huge statements and the over promise that leads
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to the negative perception of the industry by the media
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and by some of the consumers. It's oftentimes hard to
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measure impact and outcomes, especially when you deal with human lifespan,
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which you know is obviously multi decade long. So how
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can you meaningfully prove to people that it can work
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amongst a lot of users? There is poor retention and
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follow through, so a lot of people that typically are
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excited to start it out, to try it out, to
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do the procedures or take.
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Whatever supplements or some other you know, more more.
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Advanced interventions, but they typically there's very low follow through,
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so it's almost a cliff when we identified a number
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of startups from their first client or first you know
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intervention to the next one. And then generally within the
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market context sees a lot of longevity companies overlap with biotech.
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There is generally a biotech downturn, so it's at historical
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lows over the past couple of decades, so that leads
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to scarcity of capital. And on the next slide, I'm
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sharing a few quotes from a few people. I tried
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to make it a semi anonymous because some of these
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conversations were just private or chatter and rule, but I
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found it to be interesting. And these conversations are all
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from the past three four weeks, by the way.
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So.
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Both from a CEO of a public company who said
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we had to pretend to be a biotech company for
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our i PO and not talk about longevity or else
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the markets would freak out. Then I talked to a
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fund who also says we promised to our LPs to
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allocate to conservative pharma place and just a little bit
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to longevity because otherwise we struggle to raise money. Another
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startup company said we target disease X rather than aging
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to look more credible to investors. And lastly, a you
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know researchers said, we pretend not to work on radical
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longevity because we don't want we want to continue receiving
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research grants. And they also said, we don't want to
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a random religious fanatic to come and shoot us. So
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these are all real like quotes from pretty serious companies,
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people or funds I've met. So it's a lot about perception,
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how the investors perceive it, so we need to change
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the narrative and the perception amongst the investors. And then
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the last bit also of course, talks about personal safety
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of some people who are working on more radical aspects
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of longevity. And I met quite a few people who
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prefer to stay in stealth, for example, because they are saying,
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I'm not sure you know if somebody might come and
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try and shoot us. So these are definitely So the
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previous conversation about the necessary necessity of lobbying definitely is
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important than just generally engaging media, the public opinion and
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so on is equally important. So yeah, when I was
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interviewed after ARDD like, so what's your conclusion from a
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R I said, well, I guess we're all going to die.
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So there is a lot of you know, like, there
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is a lot of course progress. But then at the
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same time, as at LBF whom someone mentioned today, the
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Longevity Biotech Fellowship in which I participated, their you know,
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their main argument is that as of today, there are
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zero credible, credibly verifiable like longevity interventions on the market,
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and it's important to be aware of that that this
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is you know, we still have a lot of things
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to go. But you know, I was asked to be
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optimistic for this presentation.
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Therefore, let me.
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Say why I am here and not just like giving
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up and left. I think the market opportunity for longevity
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is definitely there. I was asked to prepare like estimates
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of the market size and so on.
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I didn't want to give random numbers. I'm not a
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fan of that.
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So I couldn't find any credible estimates of the market.
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And not least because well, when you have no definition
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for what kind of market you're talking about, it's hard
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to find an estimate. So I have seen various attempts
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to extrapolate to biotech space or set up peutics.
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Or farm or healthcare.
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I definitely am not the best person to judge which
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of those is suitable.
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But importantly there are here on champions.
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Like from the previous quote I showed you the company
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that is a public, publicly tradable company that has to
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pretend to be just we're a normal biotech or we're
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a normal pharma company. They are actually the head on
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champions of longevity. And hopefully when it becomes more acceptable
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for the public and investors to support the notion of
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increasing lifespan and health span, they can be more open
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about it and that can create a snowball effect. Secondly, well,
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I think there's just generally speaking, an infinite market size
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because who does not want to be healthier?
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Like if lifespan.
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Extension is maybe there are more people who could argue
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about that. I don't think there's barely anyone in the
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world who would not want to be healthier generally, so
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the health span part of it is a no brainer.
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The whole planet is your market when it comes to
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like living longer and so on. Again, I'm a historian
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by background, actually, so I just observe that like from
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the historical perspect from the times of pharaohs of ancient
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Egypt and the ancient kings and the emperors to the
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wealthy leads of today, a lot of them always sought immortality,
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They sought extension.
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Model of lifespan and so.
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On is deeply embedded into almost all religions, philosophies or folklore.
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The first written kind of like story, the book the
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novel Gilgamesh, you know that we have in the current
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like scnsidicly, the first book written that has stayed until
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the modern times. It deals with questions of seeking, you know, immortality.
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So therefore that leads to a lot of I want
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to believe investors, the optimist investors. Some of them come
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from fields such as crypto or AI, and there have
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been discussions that there are dreamers in a way, but
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it's important to have investors who are dreamers, who are
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not just like conservative, careful people looking for basic things.
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And I also think that a acceleration definitely brings hope
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for a lot of longevity challenges. So when people said
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these trials can take long, we're you know, simulating a
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certain kind of research can take longer, and so on.
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There is some degree of hope there, although I have
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also met a lot of people say so many things
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in biology can't really be meaningfully you know, accelerated using AI.
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And generally I'm also you know, generally looking at cycles
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in the markets. So when something is at the bottom,
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and biotech is set by everyone to be at the bottom,
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then that tends to rise.
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And investors are always.
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Looking for a good bubble, like it's just like people
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always want something that the narrative is there, and then
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they creates a snowball effect. And we are currently in
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the AI bubble obviously, but maybe the next one will
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be a longevity bubble. So briefly about our approach, so
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we tuck all this so since I mentioned that we're
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neither a VC fund nor a proper family office, so
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we take the approach of a longevity venture builder. So
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our goal is to find this promising very early stage
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startups or pre startups that try and move the needle
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on lifespan or health spun. We want them to be
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R and D and science or even not marketing things.
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So it's you know, there are plenty of others who
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can support marketing place, but we look for the evidence
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back to scientific projects and that are grounded in commercial reality,
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and therefore we're looking for such collaborations. We're actively exploring
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them now with universities and with entrepreneurship groups. As mentioned,
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we are an investorpreneur, so we are both investors and entrepreneurs.
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We try and be the founding partner and help startups
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to really focus on their operations, scaling and business growth.
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That's something that most vcs that I talk with, given
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that they have forty fifty companies in their portfolio, you
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can't meaningfully grow forty fifty companies in parallel. Even doing
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four or five companies in parallel is extremely hard. And
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therefore we want to focus on like a small group
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of superheroes. And yeah, we commet our own capital, and
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then I am working with a number of other family
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offices where I know that the principles or the family
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members themselves have a personal interest in this space. I
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like to remind the projects I work with about what
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investment actually means. A lot of them tend to just assume, Okay,
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doing longevity is good for humanity, and therefore you owe
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me money. I think that's the wrong approach, and I
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always try and like say either you know, you should
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say you're a research organization and that's fine, but if
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you're a startup, you should have a commercial model. You
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should be able to explain to your investors are going
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to bring money to them. I know it sounds like
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why is this guy explaining this? But like so many
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companies I meet, somehow just totally ignore that. And Yeah,
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the questions that we ponder upon very often. So what
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niches of longevit are worth investing in, how to do
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risk or discard a project with minimum losses? How to
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achieve both impact and profitability. It's important because we want
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to do both. Ideally, how to predict the future behavior
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of founders, that's a general startup question, not only for longevity.
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And then how to navigate the whole geopolitics and focus
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on progress and in today's world, unfortunately politics are messy,
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a lot of popularism and at least to lack of
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scientific collaboration oftentimes on top of a lot of stigmas
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that longevity itself still has today. So that is something
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we ponder upon, so that instead of you know, saying
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it's not possible to reach the stuffs and forever, we
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will add a yet that we can make it happen.
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Thank you.
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Wow, Angel, that was a powerful presentation, really fantastic. You
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covered most of everything we wanted to have in this session.
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We are very excited to have this panel to talk
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about public advocacy and what different people are doing in
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terms of advocacy. And each one will introduce themselves better
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than I can introduce them, So it is I think
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much much better to hear from them what they're working on.
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We just had a little session to know what they
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are working on, and then we will have some questions
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and debate a little bit in the panel. Okay, so
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let's begin now that we have everybody uh sitting in
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their place, and each one has a different perspective on
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what they are doing and public advocacy for longevity, but
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they are all committed to longevity and biological rejuvenation. So
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let's begin with Carmen Simon. Matteo, you have a microphone.
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You need to turn in green. Now is red. Once
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it is green, you can talk.
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Please, Thank you. An applauch to Carmen.
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So good good afternoon to everyone.
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First, I'm going to introduce myself, So I'm Carmen Simon.
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I'm a scientist.
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I work in the National Center for Biotechnology, which belongs
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to the highest public research institution.
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In Spain, which is called.
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Spanish National Research Council, and I do research. I'm a virologist.
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I work in plan virus. But I'm here because, as
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to have seen before, I found more than ten years
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ago I founded an association which is called a paternal Latentsia.
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Only with the name you already know something about it.
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And we put.
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That name A Patrina latentia because we do care about
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science and we do care about the investment in science.
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So a Vadrina Latentia is a.
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Place that has different parts of interest and along the
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journey maybe I can explain to you later what do
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we do. But the main idea is that we want
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society and also the government's understand that investment in science
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is very very important because finally all the results we
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got with our research, with our investigation finally impact in society.
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Of course, here in this meeting about longevity, so only
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we can increase in longevity and also the well being
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of people by doing research, So the investment has to
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be there, but also we want to really diffuse in
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the society the results we got in our investigations. And
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also not less important is that we are very worried
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because our kids and or young people don't want to
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be scientists, and this is really very very.
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Tough to know.
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And we want to promote the vocation of these people
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to be interested in doing science.
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So that's more or less the main ideas I.
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Wanted to show with to share with you in the
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beginning of my talk.
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Thank you, thank you very much, Carmen. So now let's
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go in a different perspective and Serchio will give us
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a few ideas of what he's doing to advance longevity.
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Cercio, Okay, yeah, I think it's best that we introduced
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ourselves briefly first and then a little longer because we
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have a lot of time. So my name is Sergio
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Martinez Ralga Taretro. I've been in the community, in the
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longevity community for about twenty years. Twenty two years. I
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met has recording a conference like this in Helsinki in
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two thousand and six, so that's nineteen years ago, and
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I've covered many conferences. I really like documenting these events.
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I think they're historical and worth preserving. And I've got
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involved with the community too to help make the ideas
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rich wider audiences. It's still kind of unfortunate that it's
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not more widespread, like Coovery said in his remarks, and
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my main contribution, I think to the community was founding
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the first plashunist political party in the world, Aljanha Patrista
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Alpha in now twelve years ago, almost to the date.
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It's the seventh of October, that's our anniversary. And exactly
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a year later, the Transformitist Party the US was founded,
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which was just chance, and we've basically brought this movement
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to existence, having a political movement around transhumanism, both the
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Allianta Patrista here in Spain and the Transumitist parties which
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were founded in first in the US and then another
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one in England I believe. I don't know if that's
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still going, but yeah, I will advocate for much more
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public investment on longevity science, obviously, which we also do
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our march to push for. But I will talk a
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little bit more about the party in a few minutes.
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I'll let the.
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Next person, beautiful, thank you. Actually we heard first a biologist,
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second assysicist by training, and now we have Clara tell us,
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how about you.
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My experience is an innovation healthcare. Hello everyone, Clara Claire Fernandez.
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I am the longevity clinic in Valencia that Anhel was
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talking about. Because last week Angel d Lan Aubrey, Natalie Ines,
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a lot of the scientists and biotech longevity biotech community,
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we're in my clinic. I hosted the Longevity Biotech Fellowship.
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My clinic is in Valencia, and I'm going to be
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talking about how the unique ecosystem and the unique model
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that we have built and how what is our perspective
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on how to democratize the access of longevity to society.
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Just as a little bit of an introduction, we are
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quite a bit clinic. We have an average of six
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hundred patients per day that stay with us for ten days,
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which has enabled us to create a unique model of
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delivering longevity treatments at a very efficient skill. One of
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the key elements that I'm going to also be talking
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about is the importance of collaboration between longevity clinics and
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the clinical scientific community. As most of the bank Guard
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treatments are happening in longevity clinics, we need to make
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sure that those data are analyzed and are translated to science,
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so we can keep supporting what's happening and publish it
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in scientific papers.
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Thank you so much, Clara.
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So let's hear from Carlos that also travels all the
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time and here's doing many things, not just in Spain,
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but all over Latin America.
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Thank you so much for inviting me. Thank you so much,
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because Luis is always a pleasure. Also from that, I'm
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very honored. I'm amazed by a number of people that
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have been here over the last few days. I'm also
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very thankful to my peers in this pandel because I've
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been hearing from them a few minutes ago. I'm very pressed.
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So my name is Carlos Ruta. I've been in this
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sector for thirty nine years. I basically do a couple
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of things. I am for profit investor, so I'm invested
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in more than eight hundred and fifty.
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Projects all over the place.
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As you said, this is for profit but not for profit,
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which is my most enthusiastic piece of the cake. I'm
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also an investor in developing what I have denominated digital
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health cities. And you would be guessing or thinking.
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What is that about. Well, this is my interpretation.
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It is only our interpretation of what we mean by that,
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but basically we create spaces. So we have in Madrid.
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We launch in Madrid on the fifth of June, the
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first digital city worldwide. We have two campuses. Campus one
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is Last marthadis eighty thousand scare meters and Campus two
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is San Fernando more than one hundred thousand scare meters.
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And what do we do there.
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Let me first very quickly remind everyone that this is
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the only sector in which the consumer, which is called patient,
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is not a decision maker. Let's keep this in mind.
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So I want to buy an iPhone, I go to
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the shop and I buy my iPhone. I'm the decision maker,
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I'm the payer, I'm the user. But in this market,
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I am the patient. But remember, there is a doctor
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who prescribes, there is someone called pharmacist who dispenses, and
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then there is someone called insurer or government who pays
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for this party, especially when we are talking about prescription.
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And then I'm the patient. I'm using these medicine medical men.
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So five six, seven stakeholders for one fact. So what
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we do in these cities is interesting. First, we put
487
00:26:28.839 --> 00:26:33.559
together public and private. This is vital, this is critical.
488
00:26:34.200 --> 00:26:37.680
This is the neurological bit of everything we do. And
489
00:26:37.799 --> 00:26:41.759
once we put together public and private sectors, we put
490
00:26:41.839 --> 00:26:45.599
together a chemist with a doctor, with an association, with
491
00:26:45.640 --> 00:26:49.759
a foundation, with a laboratory, with a distributor, and we
492
00:26:49.799 --> 00:26:51.599
make things happen in those cities.
493
00:26:51.640 --> 00:26:54.240
So our advocacy, as we.
494
00:26:54.079 --> 00:26:57.160
Were meant to say as part of this panel, is
495
00:26:58.000 --> 00:27:01.000
we am not an expert as my peer in longevity.
496
00:27:01.200 --> 00:27:05.480
I must admit actually I was a very very bad student,
497
00:27:05.680 --> 00:27:06.440
if I recall.
498
00:27:07.359 --> 00:27:09.000
But what we do is different.
499
00:27:09.319 --> 00:27:12.880
We try and do something which is in our view necessary,
500
00:27:14.200 --> 00:27:20.519
which is melting together from the entrepreneurship side of things,
501
00:27:21.359 --> 00:27:24.160
all of these people who are enthusiastic and are part
502
00:27:24.160 --> 00:27:28.519
of this ecosystem into one discussion, so we integrate. I
503
00:27:28.559 --> 00:27:31.400
would say, we are integrators, and that's how I would
504
00:27:31.440 --> 00:27:33.640
put it. And then over the next few minutes we
505
00:27:33.680 --> 00:27:36.440
will be talking more about some of the details.
506
00:27:36.559 --> 00:27:38.480
Thank you, Thanks to you, Carlos.
507
00:27:38.839 --> 00:27:42.119
And now let's hear from Marianna that I have the
508
00:27:42.160 --> 00:27:45.559
pleasure to know her for over ten years since the
509
00:27:45.599 --> 00:27:50.160
beginning of Rather First, which is the biggest global event
510
00:27:50.279 --> 00:27:54.119
on longevity revolution against agent and death.
511
00:27:54.319 --> 00:28:00.960
So Marianna and wow, yeah, thank you for the invitation.
512
00:28:01.200 --> 00:28:03.440
Thank you for having this space, thank you for bringing.
513
00:28:03.200 --> 00:28:04.240
All these people together.
514
00:28:05.640 --> 00:28:08.599
So I will be talking to you about two different
515
00:28:08.680 --> 00:28:12.920
arms to different organizations and not for profit and non profit.
516
00:28:13.359 --> 00:28:15.359
And the first one it's what you just mentioned, which
517
00:28:15.359 --> 00:28:17.400
is what brought us together and how we met and
518
00:28:17.440 --> 00:28:19.160
how I've met a lot of you and a lot
519
00:28:19.200 --> 00:28:22.680
of the people that have spoken this weekend. It's the
520
00:28:22.759 --> 00:28:25.559
Coalition for Radical Ethe Extension. It's been and not for
521
00:28:25.599 --> 00:28:30.000
profit created about eleven years ago, and then its main
522
00:28:30.039 --> 00:28:32.920
mission was to bring together and bridge the gap between
523
00:28:33.000 --> 00:28:37.960
scientists and non scientists. So yesterday doctor memmoth Can and
524
00:28:38.000 --> 00:28:41.079
then several of the speaker since then has spoken about
525
00:28:41.119 --> 00:28:44.519
how important and bitle it is to bring non scientists
526
00:28:44.519 --> 00:28:48.359
together with scientists. And that's what RADFST has been very
527
00:28:48.359 --> 00:28:52.680
successful at. We've created and launched and helped and aid
528
00:28:52.759 --> 00:28:57.079
a lot of collaboration between scientists and also bring their
529
00:28:57.200 --> 00:29:00.759
science into the forefront for the people that are actually
530
00:29:00.880 --> 00:29:03.519
the consumers, the people like us, the people that are
531
00:29:03.559 --> 00:29:06.680
sitting here who want these technologies that they need to
532
00:29:06.759 --> 00:29:09.200
know that these are happening, and also people doing the
533
00:29:09.240 --> 00:29:12.599
public advocacy, like I have some people here and Dylan
534
00:29:12.759 --> 00:29:16.599
also as well. And then the People Unlimited is and
535
00:29:16.640 --> 00:29:20.480
not for it's a profit organization, and that is being
536
00:29:20.519 --> 00:29:23.839
the longest standing and most active and most successful community
537
00:29:24.319 --> 00:29:27.720
for individuals who are interested in super longevity and what
538
00:29:27.799 --> 00:29:30.279
they do and what we've done, and I've been a
539
00:29:30.279 --> 00:29:33.640
member for eighteen years. It's to bring people that are
540
00:29:33.759 --> 00:29:36.960
mostly non scientists, but bring them together and to create
541
00:29:37.079 --> 00:29:42.400
spaces of education and inspiration. And really it's been transforming
542
00:29:42.559 --> 00:29:45.160
for all of its members and all the speakers. Actually,
543
00:29:45.599 --> 00:29:49.680
Liss Perish gave her first presentation right after she got
544
00:29:49.720 --> 00:29:53.680
hur gene therapy done first People Unlimited because she was
545
00:29:53.759 --> 00:29:56.400
recommended to it. She knew and they knew that it
546
00:29:56.440 --> 00:29:59.119
was going to be the best and most supportive platform
547
00:29:59.160 --> 00:30:03.079
for her to get started on this path. So again
548
00:30:03.240 --> 00:30:05.920
I'll just be talking about how important it is to
549
00:30:05.960 --> 00:30:07.000
bring us all together.
550
00:30:07.160 --> 00:30:08.240
I do really.
551
00:30:07.960 --> 00:30:12.920
Feel that community is community and people are the scaffolding
552
00:30:13.039 --> 00:30:17.640
of longevity and super longevity medicine and the reason why
553
00:30:17.680 --> 00:30:21.000
we're doing this. And so if you know what is
554
00:30:21.039 --> 00:30:24.799
it that brought us all together, there's a little spark
555
00:30:25.000 --> 00:30:27.039
that sparked in all of us that got us interested
556
00:30:27.160 --> 00:30:30.319
enough in longevity beyond the health system that we know of,
557
00:30:30.839 --> 00:30:34.079
and so that spark and what these organizations are doing,
558
00:30:34.160 --> 00:30:37.839
it's really throwing fire at that you know, trying locks
559
00:30:37.839 --> 00:30:40.920
at that fire, and making sure that they don't extinguish themselves,
560
00:30:41.200 --> 00:30:44.680
that everybody gets seen and supported, and that there's this
561
00:30:44.799 --> 00:30:47.640
African proverb that I really like that it says, if
562
00:30:47.680 --> 00:30:50.279
you want to go fast, go alone, but if you
563
00:30:50.319 --> 00:30:52.000
want to go further, go together.
564
00:30:52.319 --> 00:30:54.160
So that's what I'm going to be talking about today.
565
00:30:55.079 --> 00:30:59.000
Fantastic And I forget to say that Mariana was also
566
00:30:59.119 --> 00:31:03.480
born in my name country, in Venezuela, and she's doing
567
00:31:03.480 --> 00:31:04.319
incredible work.
568
00:31:04.759 --> 00:31:08.880
And the next year we are going to.
569
00:31:08.880 --> 00:31:13.480
Have the Work for Longevity, the March for Longevity in Washington,
570
00:31:13.599 --> 00:31:17.799
d C. Yes, just like we had yesterday in Madrid,
571
00:31:18.480 --> 00:31:20.200
but by by.
572
00:31:20.839 --> 00:31:24.880
Very big because numbers matter and visibility matters, and having
573
00:31:25.079 --> 00:31:27.440
you know what you had yesterday, a full room of
574
00:31:27.480 --> 00:31:30.720
people here makes such a big difference rather than just
575
00:31:30.759 --> 00:31:34.559
having a few people. So imagine having hundreds of people
576
00:31:34.640 --> 00:31:38.880
marching in d C advocating for longevity rights. And like
577
00:31:39.160 --> 00:31:41.440
how we've heard from different people the option to be
578
00:31:41.480 --> 00:31:44.119
able to obtain into some of these treatments and protocols
579
00:31:44.119 --> 00:31:47.279
we've been talking about and learning about. So that is
580
00:31:47.319 --> 00:31:49.400
something that we're working on, and we'll know in a
581
00:31:49.440 --> 00:31:52.279
couple of months if it's ago, but we'll make sure
582
00:31:52.319 --> 00:31:54.480
that everybody knows what. We're very excited about it.
583
00:31:55.160 --> 00:31:57.480
So now you know you all have to come and
584
00:31:57.559 --> 00:32:01.039
join us in Washington, d C. For the March for
585
00:32:01.200 --> 00:32:05.000
Longevity in the capital of the USA and some people
586
00:32:05.039 --> 00:32:09.799
say the capital of the world. Anyway, let's finish with
587
00:32:09.799 --> 00:32:14.119
my dear friend Cody Dean, who is the global ambassador
588
00:32:14.400 --> 00:32:19.200
of a new fantastic initiative called immortali Is, and he's
589
00:32:19.200 --> 00:32:22.119
from Florida, which is a beautiful state.
590
00:32:22.319 --> 00:32:23.759
Sonny in Florida Court.
591
00:32:24.079 --> 00:32:26.640
Thank you, Jose And yes, Florida is very beautiful and
592
00:32:26.759 --> 00:32:29.000
I look forward to being at that march in Washington,
593
00:32:29.079 --> 00:32:31.319
DC next year. I hope to see many of you there.
594
00:32:31.880 --> 00:32:35.519
So I work with Immortalis, which is a global initiative.
595
00:32:35.920 --> 00:32:38.519
We're very focused right now in the United States and
596
00:32:38.720 --> 00:32:42.279
a South American country, both of which we're calling it
597
00:32:42.640 --> 00:32:45.480
Niovia to be a little bit more agreeable to a
598
00:32:45.519 --> 00:32:48.839
more conservative crowd. But what we're trying to do is
599
00:32:49.559 --> 00:32:52.880
advocate for many of you who does have more of
600
00:32:52.880 --> 00:32:57.440
that scientific background, because I don't have a scientific background,
601
00:32:57.440 --> 00:33:00.480
But what I do have is a drive to live healthy,
602
00:33:00.920 --> 00:33:04.680
much much longer than it's currently possible. So I have
603
00:33:04.839 --> 00:33:08.079
been at events like Radfest supporting you for a long
604
00:33:08.119 --> 00:33:11.440
long time. And when I finally connected with the founder
605
00:33:11.559 --> 00:33:15.079
of Immortalis Mark Hamilton, who's over here, I knew I
606
00:33:15.119 --> 00:33:18.240
had to jump on board with that because what we
607
00:33:18.279 --> 00:33:23.720
are doing to help you, help us live is it's incredible.
608
00:33:23.960 --> 00:33:27.480
What we're trying to do is unlock the funding that
609
00:33:27.559 --> 00:33:31.279
so many of you desperately need. And part of the
610
00:33:31.319 --> 00:33:35.319
way we're doing that is by accelerating some of the
611
00:33:35.359 --> 00:33:39.559
regulatory pathways that are slowing things down. So when that happens,
612
00:33:39.839 --> 00:33:44.680
investors will begin to see a better return on their investment,
613
00:33:44.839 --> 00:33:49.440
both in profit margin and in timeline, and so you'll
614
00:33:49.440 --> 00:33:54.440
see an influx of investment opportunity into you into what
615
00:33:54.480 --> 00:33:57.960
you're doing when we successfully unlock a zone, and you'd
616
00:33:57.960 --> 00:34:01.680
be surprised how close we are, even within the United States,
617
00:34:01.680 --> 00:34:05.480
which has been historically tough to get into. So you know,
618
00:34:05.519 --> 00:34:09.320
stay tuned for what's happening there could potentially be you know,
619
00:34:09.440 --> 00:34:11.440
the end of the year early in the next year.
620
00:34:11.760 --> 00:34:16.840
You know, politics is a very interesting landscape, so we'll see.
621
00:34:17.320 --> 00:34:20.840
But once that is unlocked and you're able to come
622
00:34:20.880 --> 00:34:25.440
in and do what you do much much faster and
623
00:34:25.880 --> 00:34:31.400
with more funding behind you and still cheaper, you're going
624
00:34:31.440 --> 00:34:33.559
to be able to save our lives faster, which is
625
00:34:33.599 --> 00:34:35.159
selfishly what I want.
626
00:34:35.679 --> 00:34:41.639
So that's us fantastic Cody, and now I want to
627
00:34:41.679 --> 00:34:45.320
go into a second round to see what they are
628
00:34:45.360 --> 00:34:49.159
doing on their background is related to public advocacy because
629
00:34:49.239 --> 00:34:53.679
part of the International Longevity Summit is to have an impact,
630
00:34:53.800 --> 00:34:56.559
an impact on people, and you have seen we have
631
00:34:56.679 --> 00:35:00.320
had two documentaries. We have been in all all the
632
00:35:00.400 --> 00:35:03.800
media in Spain, you know, the media soon attacking us
633
00:35:03.800 --> 00:35:08.039
by the way, they cannot understand that we believe that
634
00:35:08.119 --> 00:35:11.360
this is science and technology that we are going to
635
00:35:11.440 --> 00:35:16.719
be able to live longer, healthier, better. So I don't
636
00:35:16.800 --> 00:35:19.679
understand how some people can attack this beautiful idea.
637
00:35:19.800 --> 00:35:21.719
But anyway, we are in all media, so.
638
00:35:21.639 --> 00:35:25.320
This is fantastic, all TVs, radio, newspapers. We had the
639
00:35:25.360 --> 00:35:28.440
major of Madrid, I mean we can go much higher,
640
00:35:28.639 --> 00:35:32.320
who is a very important person. And we had the
641
00:35:32.400 --> 00:35:36.480
March for Longevity. We had a lot of things going on,
642
00:35:36.559 --> 00:35:39.440
and we have fantastic speakers in all sessions, including these
643
00:35:39.480 --> 00:35:44.039
beautiful planet So how can we move the movement forward?
644
00:35:44.920 --> 00:35:48.280
How can we impact? So this is the main idea that.
645
00:35:48.559 --> 00:35:53.960
Appears when a Parina Athinia was born. So in escent
646
00:35:54.039 --> 00:35:57.840
Tom which is the vice president, myself and some other scientists,
647
00:35:57.920 --> 00:36:00.800
we wanted really to have an impact, not only with
648
00:36:00.920 --> 00:36:04.440
our research, but also to tell the society how important
649
00:36:04.559 --> 00:36:08.480
is science. So if you pay attention to the richest
650
00:36:08.480 --> 00:36:13.079
countries and the best countries in the world are those
651
00:36:13.159 --> 00:36:17.840
which have invested a lot of money in science, and
652
00:36:17.880 --> 00:36:21.360
because of these results that appeal. Finally they have an
653
00:36:21.400 --> 00:36:25.440
impact and finally the society can really feel the impact
654
00:36:25.480 --> 00:36:29.119
of this research. Something important that I would like to
655
00:36:29.199 --> 00:36:34.079
mention is the importance of do research, do investigation in
656
00:36:34.320 --> 00:36:38.960
every areas of knowledge. So the challenges we have in
657
00:36:39.000 --> 00:36:42.480
front of us in this century and in the centuries
658
00:36:42.559 --> 00:36:46.760
are really important and very big, and only through the
659
00:36:46.840 --> 00:36:52.000
collaboration and interdisciplinarity of all areas of knowledge we can
660
00:36:52.119 --> 00:36:56.000
give an answer to this to solve these problems. So
661
00:36:56.599 --> 00:37:01.519
this is also something that we really focus on when
662
00:37:01.559 --> 00:37:04.280
we are working in a paternal latentia.
663
00:37:04.760 --> 00:37:07.719
And this makes also very singular.
664
00:37:07.519 --> 00:37:12.519
Our associations, so you maybe see another different foundations, many
665
00:37:12.559 --> 00:37:16.800
different associations that pay attention to one specific subject.
666
00:37:17.159 --> 00:37:19.880
In a paternal athentia, we pay attention to all.
667
00:37:19.880 --> 00:37:23.599
Areas of knowledge and this is something singular and also
668
00:37:23.679 --> 00:37:28.519
as strength. Another singular part of patental things and one
669
00:37:28.559 --> 00:37:31.079
of our strengths is that is leaded.
670
00:37:30.719 --> 00:37:32.880
And directed by scientists.
671
00:37:33.360 --> 00:37:37.920
So we are used to manage our group, lead our
672
00:37:37.960 --> 00:37:43.000
group research groups and also we manage the We get
673
00:37:43.039 --> 00:37:47.159
funding from many different funding agencies, not only national but
674
00:37:47.199 --> 00:37:51.159
also international, and we know really which are the problems
675
00:37:51.519 --> 00:37:55.159
and we know very well how with very little amount
676
00:37:55.239 --> 00:37:57.480
of money to have an impact.
677
00:37:57.159 --> 00:37:58.039
In our research.
678
00:37:58.880 --> 00:38:02.599
That's why all the fundly we got we made open
679
00:38:02.679 --> 00:38:06.960
calls and they have all the projects we receive, all
680
00:38:07.119 --> 00:38:11.000
all the proposals are evaluated by scientists. That's why they
681
00:38:11.039 --> 00:38:15.199
impact each much higher. So this is something that I
682
00:38:15.239 --> 00:38:18.199
will want to share you because if you put money
683
00:38:18.280 --> 00:38:22.199
in you, if you make a donation to a Padina Latinia,
684
00:38:22.480 --> 00:38:25.199
you can be sure that all these money are going
685
00:38:25.239 --> 00:38:28.559
to be optimized. It's not a waste of money, but
686
00:38:28.679 --> 00:38:32.400
an investment in science, an investment to get results and
687
00:38:32.559 --> 00:38:36.840
finally an investment to get an impact in the society.
688
00:38:38.599 --> 00:38:40.559
Thank you so stell here.
689
00:38:40.920 --> 00:38:43.679
So I prepare these graphics as I've been doing for
690
00:38:43.719 --> 00:38:47.039
these conferences for the last few years. My name is,
691
00:38:47.199 --> 00:38:50.280
as I said, Sergio Martinaterero, and I'm producing all these
692
00:38:50.360 --> 00:38:54.239
videos on the streaming partly as a donation of a tourista.
693
00:38:54.559 --> 00:38:57.000
I'll let you know that we're changing the logo. It's
694
00:38:57.000 --> 00:39:02.719
a political party. I discussed and fired on these stages
695
00:39:02.760 --> 00:39:06.519
of life picture. We just took you know, the part
696
00:39:06.559 --> 00:39:09.800
after aging, because otherwise it would be too big of
697
00:39:09.880 --> 00:39:12.599
us a logo. But I lived up there for now,
698
00:39:13.239 --> 00:39:16.159
and yes I've covered just as part of this two
699
00:39:16.199 --> 00:39:19.559
thousand and eight, Transmission, twenty one, twenty two, twenty four,
700
00:39:19.840 --> 00:39:23.559
twenty five. Now my friends Jose David Wood and many
701
00:39:23.559 --> 00:39:27.199
others go back over twenty years when I started documenting
702
00:39:27.239 --> 00:39:31.119
events like the Forssight Institute conferences, then Transition two thousand
703
00:39:31.159 --> 00:39:34.159
and six in Helsinki, twenty seven in Chicago with Charlie
704
00:39:34.199 --> 00:39:36.639
cam I don't know if it's still here, and many
705
00:39:36.639 --> 00:39:39.960
other such events. When I was growing up, I was
706
00:39:40.079 --> 00:39:44.039
very concerned about the Cold War in the eighties. This
707
00:39:44.239 --> 00:39:48.760
movie Wargames really touched me, and I thought very good
708
00:39:48.800 --> 00:39:52.800
movies about important subjects could really change the world and
709
00:39:53.000 --> 00:39:56.800
educate people. And everybody gets to hear about ideas to
710
00:39:56.880 --> 00:40:00.480
the end of the world. Everybody knows Rocky Balb and
711
00:40:00.519 --> 00:40:04.360
the Terminator, and you can really reach out with the
712
00:40:04.360 --> 00:40:08.320
film medium. So when I was growing up, I thought
713
00:40:08.320 --> 00:40:10.760
it was easier to influence the world through movies than
714
00:40:11.480 --> 00:40:13.920
doing politics. I had never thought about going into politics
715
00:40:14.000 --> 00:40:14.960
until much much.
716
00:40:14.800 --> 00:40:18.559
Later, many many years later.
717
00:40:19.239 --> 00:40:22.280
In two thousand and two or so, I was studying
718
00:40:22.280 --> 00:40:24.400
how the Best incorporated the idea of my medical evolution
719
00:40:24.559 --> 00:40:28.400
into a script. I inadvertently discovered transhumanism and the prospect
720
00:40:28.440 --> 00:40:33.159
for molecular technology artificial superintelligence changing the world drastically in
721
00:40:33.199 --> 00:40:36.760
a matter of a future decades. I decided to get
722
00:40:36.800 --> 00:40:40.519
involved and to get informed, and to see what I
723
00:40:40.519 --> 00:40:44.679
could do to help this movement to get us there
724
00:40:44.800 --> 00:40:49.000
quicker but safer. I realized that the issues regarding these
725
00:40:49.079 --> 00:40:53.920
ultra technologies like molecular nanotechnology and superintelligence were so grave
726
00:40:54.679 --> 00:40:57.920
and so urgent, while at the same time so promising
727
00:40:57.960 --> 00:41:00.360
and liberating, that I should focus more on how I
728
00:41:00.360 --> 00:41:03.639
could influence their positive development while avoiding the worst risks.
729
00:41:04.239 --> 00:41:07.039
Ever since, I have you know, recorded all these conferences
730
00:41:07.119 --> 00:41:08.960
as part of my effort to help brow the movement
731
00:41:09.400 --> 00:41:12.840
from all the ideas and make the videos look good
732
00:41:12.880 --> 00:41:17.239
hopefully or better every year, and just to document them
733
00:41:17.239 --> 00:41:20.920
for the record. After twenty ten or so, my thoughts
734
00:41:20.960 --> 00:41:23.079
about super moral ais made me give a lot of
735
00:41:23.119 --> 00:41:25.920
thoughts to the Way with three Animals, and I got
736
00:41:26.159 --> 00:41:29.679
interested in animal ethics just to make friends and stuff
737
00:41:29.719 --> 00:41:32.880
and to learn about it. I volunteered for an animal
738
00:41:33.000 --> 00:41:36.239
rights political party, PATMA, and part of the animalist at
739
00:41:36.239 --> 00:41:39.039
PATMA here in Spain for about a year. Then I
740
00:41:39.199 --> 00:41:42.559
realized that something was missing in this party and basically
741
00:41:42.639 --> 00:41:46.000
in every other political party which is a strong feminist component.
742
00:41:47.880 --> 00:41:51.719
I'd witness political debates within the movement for about a decade.
743
00:41:52.599 --> 00:41:57.599
They're very interesting and you know, enlightening and edifying, but
744
00:41:59.119 --> 00:42:02.840
there was any being done. So I decided to start
745
00:42:02.840 --> 00:42:05.239
the first political party with a few friends here in Spain.
746
00:42:05.840 --> 00:42:08.880
Founding it was easy. Then we had to develop the
747
00:42:08.920 --> 00:42:11.440
ideas further and it took time. It took years to
748
00:42:11.480 --> 00:42:14.119
really develop our declaration of principles from a small document
749
00:42:14.159 --> 00:42:19.440
into what it is today and we continued recording videos
750
00:42:19.440 --> 00:42:22.880
and conferences are in twenty fourteen with an AI conference
751
00:42:22.920 --> 00:42:27.039
in Santander were for later organized as well, and just
752
00:42:27.199 --> 00:42:31.000
continued Crionist conferences and this and that, just many many things.
753
00:42:31.280 --> 00:42:35.159
We had an unfortunate passing in the party, Havier with
754
00:42:35.360 --> 00:42:39.320
the past, and we managed to honor his will of
755
00:42:39.360 --> 00:42:44.239
getting him cryonically preserved. But yeah, the party kind of
756
00:42:44.239 --> 00:42:48.880
revived and got new people in. And we also have a,
757
00:42:49.039 --> 00:42:51.519
like I said, a strong animal latist component, and other
758
00:42:51.559 --> 00:42:56.880
dimensions of political discussion that go beyond life extension. We're
759
00:42:56.920 --> 00:43:01.800
also extremely concerned with big global catastrophic risk existential risks
760
00:43:01.800 --> 00:43:05.239
that certain technologies could bring about, and so our Declaration
761
00:43:05.280 --> 00:43:08.920
of principles grew. Let me see if I have just
762
00:43:09.159 --> 00:43:11.280
an image of it. You should take a look at
763
00:43:11.320 --> 00:43:15.159
the document yourself. Yeah, it's from something small to something
764
00:43:15.360 --> 00:43:18.519
that's something like twenty five pages long today, and it's
765
00:43:18.800 --> 00:43:21.000
we're pretty proud of it, and we wrote it every
766
00:43:21.199 --> 00:43:22.920
few months. We have a new update. The last one
767
00:43:23.000 --> 00:43:25.079
is just a few days old, so feel free to
768
00:43:25.079 --> 00:43:33.280
take a look. Yeah, and I would like to read
769
00:43:33.320 --> 00:43:36.320
briefly Kennedy's historian offs from Mars. In a recent email
770
00:43:36.559 --> 00:43:40.280
from the Transhumitist Party in the US, he wrote this
771
00:43:41.320 --> 00:43:43.519
short text. It's nice, so I'll just read it for you.
772
00:43:43.840 --> 00:43:46.719
Aleantha Fatriista and the US Transumitist Party are the true
773
00:43:46.840 --> 00:43:50.280
oldest transhumanist political parties in the world. We have endured
774
00:43:50.320 --> 00:43:52.679
because we are guided by long term goals and enduring
775
00:43:52.760 --> 00:43:56.880
vision of our transhumanist pursuits and transform the human condition
776
00:43:57.000 --> 00:43:59.880
for the better, rather than focusing narrowly on winning election
777
00:44:00.239 --> 00:44:04.039
or beating other political parties. Ultimately, transhumanism is a global
778
00:44:04.039 --> 00:44:07.119
movement that leads to unite humans in our share aspiration
779
00:44:07.360 --> 00:44:13.039
to overcome all age limits of mortality, disease, materialscustody, and irrationality. Therefore,
780
00:44:13.039 --> 00:44:16.280
political success of trust humanists anywhere in the world is
781
00:44:16.320 --> 00:44:19.159
a success for trusumanist everywhere in the world. Any jurisdiction
782
00:44:19.320 --> 00:44:23.239
where transhumanism succeeds in influencing government policy in a direction
783
00:44:23.280 --> 00:44:26.039
that is more open to technological advancement will be a
784
00:44:26.119 --> 00:44:31.360
jurisdiction where research breakthroughs courrecture to benefit humanity. The US
785
00:44:31.519 --> 00:44:34.559
TP considers aliataa Trista to be its key ally in Spain,
786
00:44:34.679 --> 00:44:37.199
and we are eager to see what its efforts can
787
00:44:37.199 --> 00:44:39.679
accomplished to enable Spain to become one of the foremost
788
00:44:40.000 --> 00:44:44.400
prolengevity countries of our time. Ali Asafadrista is welcome. This
789
00:44:44.480 --> 00:44:47.159
has to do with our suggestion that we would sign
790
00:44:47.320 --> 00:44:52.559
their values document and that in our declarations they have
791
00:44:52.639 --> 00:44:57.440
the Transhumitist Party Values and Trushumanists Bill of Rights, and
792
00:44:57.480 --> 00:45:00.159
so we already passed it in our party work sign
793
00:45:00.239 --> 00:45:02.119
this declaration and will add it to this part of
794
00:45:02.199 --> 00:45:05.159
the website in the next few days. It's an announcement
795
00:45:05.199 --> 00:45:09.159
I'm making as more of an interconnection between our two
796
00:45:09.199 --> 00:45:14.199
parties because we should really strongly support each other. And yeah,
797
00:45:14.800 --> 00:45:19.679
now just briefly, I would like to I would like
798
00:45:19.719 --> 00:45:22.159
you all and everyone you know to help these parties,
799
00:45:22.159 --> 00:45:24.000
to help Alianta to this die if you can to
800
00:45:24.039 --> 00:45:27.880
get involved, to get to get to know us, and
801
00:45:29.119 --> 00:45:32.960
there's memberships, there's you can make donations. There's a pretty
802
00:45:33.039 --> 00:45:35.960
high limit in Spain for donations, so if anyone has money,
803
00:45:36.159 --> 00:45:40.159
it can help us grow much faster, and especially human
804
00:45:40.679 --> 00:45:45.639
force human you know members, especially within Spain, so I
805
00:45:45.679 --> 00:45:47.880
know some of you are Spanish or people in Spain
806
00:45:47.920 --> 00:45:51.280
are watching through the subtitles et cetera. So we need
807
00:45:51.440 --> 00:45:54.719
people to have the different areas of the party. If
808
00:45:54.760 --> 00:45:59.480
you like, if yours, especially an expert on any of
809
00:45:59.519 --> 00:46:01.800
the fields we talk about, come to us so you
810
00:46:01.840 --> 00:46:04.280
can head one of the departments or something like that.
811
00:46:05.000 --> 00:46:08.320
And yeah, that's basically. I don't know if I have anymoreuslightes.
812
00:46:08.639 --> 00:46:10.760
We were showing the Bill of Rights and all of
813
00:46:10.800 --> 00:46:13.400
these things briefly, but yeah, there's a code if you
814
00:46:13.440 --> 00:46:15.079
want to reach the website quicker.
815
00:46:15.719 --> 00:46:19.639
Thank you, okay, thank you Serkio for all you are doing.
816
00:46:20.000 --> 00:46:24.360
And now we want to bring back the beautiful, the intelligent,
817
00:46:24.559 --> 00:46:27.639
the expert on all of this, Sabini.
818
00:46:28.800 --> 00:46:29.599
Thank you, thank you.
819
00:46:30.280 --> 00:46:31.639
So are you all energized?
820
00:46:32.239 --> 00:46:37.559
Yes, yes, well we have a little energy left.
821
00:46:37.639 --> 00:46:39.079
We're going to have a few more speakers.
822
00:46:39.079 --> 00:46:41.840
Look at this eminent speaker panel sitting here, it's amazing.
823
00:46:42.239 --> 00:46:44.840
I want to start off by introducing our next speaker,
824
00:46:45.079 --> 00:46:48.239
who really has many engagements in longevity. Two of them
825
00:46:48.360 --> 00:46:52.480
are as CEO of Balerno, the largest longevity clinic in
826
00:46:52.639 --> 00:46:56.599
Europe that can host up to fifteen thousand patients, and also.
827
00:46:56.440 --> 00:46:57.920
CEO pro Jevita.
828
00:46:58.039 --> 00:47:01.360
I hope I can announce that a longevity retreat that
829
00:47:01.440 --> 00:47:04.639
then is more geared towards business people and C suites.
830
00:47:05.000 --> 00:47:08.239
And she's also the co founder of our ex Longevity,
831
00:47:08.280 --> 00:47:11.719
a longevity coach app so she is truly, truly well
832
00:47:11.800 --> 00:47:13.920
versed in the longevity space. Please give it up for
833
00:47:14.000 --> 00:47:22.360
Clara Fernandez Porta.
834
00:47:24.559 --> 00:47:29.039
Hi, everyone, So when Jose asked me to talk about
835
00:47:29.480 --> 00:47:33.639
public advocacy and how our clinic or our model was
836
00:47:33.719 --> 00:47:37.559
working to help push the longevity science, I was very
837
00:47:37.559 --> 00:47:39.800
happy to be here and be able to share you
838
00:47:40.039 --> 00:47:44.039
how I have actually designed the clinic to make sure
839
00:47:44.119 --> 00:47:47.599
that we could become a tool for society, for both
840
00:47:47.760 --> 00:47:52.239
patients and scientists to push up longevity as much as possible.
841
00:47:52.599 --> 00:47:56.480
So I have some slices. So just before you understand
842
00:47:56.519 --> 00:47:58.280
and I'm gonna talk, I'm gonna be I have a
843
00:47:58.320 --> 00:48:01.119
short presentation, but just be or I started telling you
844
00:48:01.519 --> 00:48:04.039
a little bit more about my clinic, I want to
845
00:48:04.039 --> 00:48:07.559
give you some context. So we're in Valencia, in the
846
00:48:07.599 --> 00:48:10.679
middle of the forest. We have over two million square
847
00:48:10.719 --> 00:48:14.400
meters in the middle of the forest, over eighty different buildings.
848
00:48:14.880 --> 00:48:18.880
It is traditionally a historical thermal clinic, which in Europe
849
00:48:18.920 --> 00:48:22.519
is very popular. So it was originally created to create
850
00:48:22.719 --> 00:48:26.360
natural medicine treatment, but over the last thirty years the
851
00:48:26.440 --> 00:48:29.719
company has evolved in the area of healthy aging and
852
00:48:29.800 --> 00:48:33.440
health and longevity. So the company is actually founded by
853
00:48:33.880 --> 00:48:36.199
it's a family company, so it's founded by my father
854
00:48:36.559 --> 00:48:40.119
who is here a doctor, and as a family company,
855
00:48:40.159 --> 00:48:43.079
we have been able to decide and create the strategy
856
00:48:43.119 --> 00:48:45.599
that we thought would have the biggest impact in society.
857
00:48:46.280 --> 00:48:50.559
We are initially focused on people from sixty to seventy
858
00:48:50.639 --> 00:48:55.639
years because we believe that's in the longevity clinic ecosystem.
859
00:48:55.679 --> 00:48:59.840
We believe that is the unique segment that has time
860
00:49:00.559 --> 00:49:05.480
and willingness to dedicate themselves to that to longevity treatments,
861
00:49:06.320 --> 00:49:08.559
and so that has enabled us to create a model
862
00:49:08.880 --> 00:49:11.719
where patients come every day. We have an average of
863
00:49:11.800 --> 00:49:15.440
sixty patients coming every day for ten days staying with us,
864
00:49:15.679 --> 00:49:20.119
with six hundred patients as I mentioned, staying with us together.
865
00:49:20.320 --> 00:49:23.159
And we have been able to create a framework of
866
00:49:23.280 --> 00:49:29.320
treatments that I've been able to democratize longevity treatments. So anyway,
867
00:49:29.320 --> 00:49:31.159
what I was going to tell you is how we
868
00:49:31.239 --> 00:49:33.599
actually have created the ecosystem, because I think it's very
869
00:49:33.679 --> 00:49:37.719
unique and very different to most of the other longevity clinics,
870
00:49:37.719 --> 00:49:41.559
and that has been the core element that has given us.
871
00:49:41.039 --> 00:49:42.599
The unique advantage to.
872
00:49:42.559 --> 00:49:46.280
Both skill or super great. So here you can have
873
00:49:46.360 --> 00:49:50.360
my information also my website. So first of all, the
874
00:49:50.400 --> 00:49:53.559
most important thing that is different, Okay, I told you
875
00:49:53.599 --> 00:49:55.280
so we have an average of one hundred and sixty
876
00:49:55.320 --> 00:49:59.519
thousand patients per year daily patients. That makes us and
877
00:49:59.559 --> 00:50:02.599
the biggest hotel in the province of Valencia, which is
878
00:50:02.639 --> 00:50:06.519
a very touristic hotel. But what actually has the scale
879
00:50:06.519 --> 00:50:09.599
and number of patients has given us is the possibility
880
00:50:09.679 --> 00:50:13.599
to create accessible treatments. And why is this. Most of
881
00:50:13.599 --> 00:50:18.800
the traditional longevity techniques that you know have a smaller scale,
882
00:50:18.800 --> 00:50:21.039
and that makes that most of the cost of the
883
00:50:21.079 --> 00:50:24.840
treatments are not necessarily uniquely the cost of medicine per se,
884
00:50:25.239 --> 00:50:28.280
but the cost of the set up. So being big
885
00:50:28.760 --> 00:50:31.960
is for us from a fundamental part of being able
886
00:50:32.000 --> 00:50:35.760
to have a big scientific a big medical team, a
887
00:50:35.800 --> 00:50:39.239
big scientific team and make sure that we can deliver
888
00:50:39.440 --> 00:50:44.159
treatments at the unique marginal cost in terms of treatments.
889
00:50:44.400 --> 00:50:46.960
Just so that you know, we're strong on red generative
890
00:50:47.000 --> 00:50:51.480
medicine and anti inflammation protocols and patients can either come
891
00:50:51.519 --> 00:50:53.880
to one of our set protocols that is a combination
892
00:50:54.000 --> 00:51:00.119
of stem cell treatments or themolecular medicines, plasma therasis, ozone therapy,
893
00:51:00.519 --> 00:51:03.719
or they can come to one of our personalized protocols.
894
00:51:04.360 --> 00:51:08.320
All of our treatments do a combination of diagnostics, treatments,
895
00:51:08.519 --> 00:51:11.719
and education. And this is also a very important part
896
00:51:11.400 --> 00:51:15.079
that I want to make points on, especially as we're
897
00:51:15.079 --> 00:51:19.039
speaking about public advocacy. Every patient that comes to our
898
00:51:19.079 --> 00:51:24.079
clinic has an average of twenty hours of longevity master classes.
899
00:51:24.639 --> 00:51:27.440
We are making sure that everyone that comes to our
900
00:51:27.519 --> 00:51:32.960
space understands the biology of aging, not only what's available today.
901
00:51:33.199 --> 00:51:38.000
We don't do this education or scientific master classes to
902
00:51:38.360 --> 00:51:43.199
get them more treatments. For us, it is fundamental that
903
00:51:43.320 --> 00:51:47.599
people understand the biology of their aging process and what
904
00:51:47.800 --> 00:51:49.880
is to come in the next years, because we believe
905
00:51:49.960 --> 00:51:52.360
that is the unique way that they're going to spread
906
00:51:52.400 --> 00:51:55.000
the word and that they are going to have an
907
00:51:55.000 --> 00:52:01.039
interest in taking care of their health. Yes, with raker Cell,
908
00:52:01.320 --> 00:52:04.000
he told us in the presentation that he believes that
909
00:52:04.079 --> 00:52:06.800
in just seven years when we might reach the longevity
910
00:52:06.840 --> 00:52:11.199
velocity of escape. Well, that's fundamental that we teach society
911
00:52:11.400 --> 00:52:15.360
because people are not going to take longevity treatments or
912
00:52:15.400 --> 00:52:18.480
their health strategy in the same way if they believe
913
00:52:18.519 --> 00:52:22.760
we are very far from having any impactful results in
914
00:52:22.800 --> 00:52:26.440
our lives, or whether they think that is actually relatively close.
915
00:52:26.719 --> 00:52:30.480
So economiest of skill enables us to have not only
916
00:52:30.719 --> 00:52:33.159
great treatments delivered to the patient, but also to do
917
00:52:33.760 --> 00:52:37.119
very specific master classes and make sure that we invest
918
00:52:37.960 --> 00:52:42.360
in creating the education and the culture that we need
919
00:52:42.400 --> 00:52:47.320
the patients to demand. Finally, because we have a lot
920
00:52:47.320 --> 00:52:49.920
of patients, we have a lot of data. So it's
921
00:52:49.960 --> 00:52:53.559
been almost I think eight years that we decided that
922
00:52:54.079 --> 00:52:57.000
one of the biggest roles that we could have in
923
00:52:57.039 --> 00:53:01.480
the longevity ecosystem was to become a plaque a platform
924
00:53:01.480 --> 00:53:05.559
from scientists, for universities and for companies so that they
925
00:53:05.599 --> 00:53:11.239
could actually research with our patient data, iterate their producals
926
00:53:11.480 --> 00:53:15.360
with our patients, and finally be able to test the
927
00:53:15.400 --> 00:53:19.480
final results. The Human Lab is a space where we
928
00:53:19.519 --> 00:53:23.199
do clinical trials, but it's also a place where we
929
00:53:23.320 --> 00:53:27.639
gather data for patients that we open for the science community,
930
00:53:27.920 --> 00:53:29.440
just so you get a little bit of a scale.
931
00:53:29.519 --> 00:53:32.440
This year we have had two point five million euros
932
00:53:32.480 --> 00:53:36.239
in grants from government from Spain and from Europe. In
933
00:53:36.360 --> 00:53:40.159
protocols that we have designed ourselves. We expect next year
934
00:53:40.199 --> 00:53:42.559
to have more than three million and to double the
935
00:53:42.639 --> 00:53:45.559
number of PhD students that are using our data to
936
00:53:45.679 --> 00:53:49.639
publish scientific research. Also, we have created a model that
937
00:53:49.679 --> 00:53:54.960
it's a digital biobank by which patients can actually leave
938
00:53:55.000 --> 00:53:59.079
their data accessible for science. The data is going to
939
00:53:59.119 --> 00:54:02.599
be sold different startups or companies, and that money is
940
00:54:02.639 --> 00:54:05.320
going to be used as a unique wallet for the
941
00:54:05.400 --> 00:54:09.079
patient that they can reinvest in their longevity treatments for
942
00:54:09.199 --> 00:54:11.639
next year. I didn't mention this, but most of our
943
00:54:11.679 --> 00:54:15.519
patients from every year, the protocols that we design are
944
00:54:15.719 --> 00:54:17.880
designed to be a pit stop, an animal pit stop.
945
00:54:18.239 --> 00:54:21.000
So they come every year, get checked up again, get
946
00:54:21.000 --> 00:54:24.280
boosted with their motivation and their classes, what's happening in
947
00:54:24.280 --> 00:54:27.880
in the biology of aging, make sure that they are
948
00:54:27.920 --> 00:54:31.119
on the right track, redesign their plan and go back home.
949
00:54:31.960 --> 00:54:36.519
So and finally, a human LAP is not just great
950
00:54:36.559 --> 00:54:40.719
because we can push science, but because having access to
951
00:54:40.800 --> 00:54:44.920
clinical trials enables us to deliver unique treatments under the
952
00:54:45.000 --> 00:54:48.480
umbrella of clinical trials. So being in contact with the
953
00:54:48.519 --> 00:54:52.239
scientific community is not just great to push the science,
954
00:54:52.599 --> 00:54:55.000
but it also is the unique way to help us
955
00:54:55.679 --> 00:54:58.239
be on the bank guard of what's happening in longevity.
956
00:54:58.679 --> 00:55:01.559
So this isn't because of because it actually feeds himself
957
00:55:01.599 --> 00:55:04.480
being able to have more clinical trials and unique clients.
958
00:55:04.480 --> 00:55:07.599
It's actually what gives us the more patient base and
959
00:55:07.639 --> 00:55:09.880
more people that are willing to come year after year,
960
00:55:09.920 --> 00:55:12.320
which gives us more economies of scale and more data.
961
00:55:13.320 --> 00:55:15.880
So this was basically the model I wanted to share,
962
00:55:15.920 --> 00:55:17.760
and I think it's very relevant because most of the
963
00:55:17.760 --> 00:55:21.199
longevitic clinics are not articulated in a way in which
964
00:55:21.239 --> 00:55:25.199
they're interrelated to the scientific community, not just the science
965
00:55:25.239 --> 00:55:28.519
that they're pushing themselves, but the general scientific community. And
966
00:55:28.559 --> 00:55:31.039
I think this is a very important message to be
967
00:55:31.079 --> 00:55:34.559
spread more of FAST could be making more treatments, more
968
00:55:34.559 --> 00:55:41.760
democratized and having a bigger impact in society.
969
00:55:48.199 --> 00:55:48.960
Thank you, Clark.
970
00:55:49.079 --> 00:55:51.960
Really interesting to see as an ecosystem thinker, I mean
971
00:55:51.960 --> 00:55:55.039
I found it very interesting. And our next speaker is
972
00:55:55.119 --> 00:55:58.920
CEO for Digital for Health Worldwide and president of mad
973
00:55:59.000 --> 00:56:03.119
eHealth flagship initiated and backed by Madrid City.
974
00:56:02.920 --> 00:56:05.360
Council, and his lifelong mission is.
975
00:56:05.280 --> 00:56:09.000
To really re architect healthcare around the patient, so be
976
00:56:09.119 --> 00:56:14.480
patient centric, fusing public and private integration, open innovation, and
977
00:56:14.559 --> 00:56:18.320
also AI into everyday care and digital health. And with that,
978
00:56:18.400 --> 00:56:22.199
I'd like to hand the word over to Carlos dis Lsa.
979
00:56:23.320 --> 00:56:24.039
Thank you so much.
980
00:56:31.159 --> 00:56:33.920
I have shared something very important with you guys a
981
00:56:33.920 --> 00:56:36.519
few minutes ago. You remember when I told you I
982
00:56:36.559 --> 00:56:41.280
was a very bad student brings a bell. I was
983
00:56:41.320 --> 00:56:44.320
a horrible student. Actually I lied to you. It was horrible,
984
00:56:44.440 --> 00:56:48.199
not bad. But I was doing something, you know, what
985
00:56:48.320 --> 00:56:52.119
I was doing very well, just one thing. Can you
986
00:56:52.159 --> 00:56:58.400
think of what I was doing, just one thing, dreaming
987
00:57:00.679 --> 00:57:03.800
one thing and trying to do it well. So I
988
00:57:03.840 --> 00:57:09.119
spent hours, if you think of university long hours, long studies,
989
00:57:10.360 --> 00:57:13.559
so I spent long hours, as all of you did,
990
00:57:13.639 --> 00:57:18.280
probably dreaming. And today I'm going to share with you,
991
00:57:18.360 --> 00:57:21.960
hopefully one of my last dreams. I've had a lot
992
00:57:21.960 --> 00:57:24.760
of nightmares by the way, also, but this is one
993
00:57:24.800 --> 00:57:26.960
of my last dreams that I have shared with you before.
994
00:57:27.039 --> 00:57:31.199
So this video is a very simple example of what
995
00:57:31.280 --> 00:57:35.960
I dreamed eight years ago, when, as I said before,
996
00:57:36.000 --> 00:57:40.280
we were trying to put together public and private sectors
997
00:57:40.920 --> 00:57:43.840
because we all think that healthcare doesn't have to be
998
00:57:43.920 --> 00:57:44.920
public or private.
999
00:57:45.079 --> 00:57:46.239
It has to be good.
1000
00:57:47.280 --> 00:57:51.000
And as far as I know, the only possible way
1001
00:57:51.119 --> 00:57:55.599
for us to deliver a very good healthcare healthcare system
1002
00:57:55.719 --> 00:58:01.639
is by unifying, putting together both sectorsublic and private. Let
1003
00:58:01.719 --> 00:58:03.880
maybe before we see the video, just say this a
1004
00:58:04.000 --> 00:58:05.320
very little piece of thought.
1005
00:58:06.159 --> 00:58:08.519
So you know healthcare systems.
1006
00:58:08.760 --> 00:58:11.719
So public is probably seventy percent of the total in
1007
00:58:11.800 --> 00:58:15.679
volumes in values. But we need a private and private
1008
00:58:15.760 --> 00:58:41.559
needs public. Are we ready, so let's go for it? Well,
1009
00:58:41.679 --> 00:58:42.480
there is no noise.
1010
00:58:45.480 --> 00:58:46.000
Yes, there is.
1011
01:01:37.920 --> 01:01:44.440
Gee that gave me so.
1012
01:01:47.039 --> 01:01:51.320
Come back, gave you.
1013
01:01:50.119 --> 01:01:50.800
Say it all.
1014
01:01:59.519 --> 01:02:09.639
And thank you so much.
1015
01:02:09.920 --> 01:02:14.719
So this is, as I said before, our last but
1016
01:02:14.880 --> 01:02:19.280
not least dream. We keep dreaming. This is the first
1017
01:02:19.280 --> 01:02:23.880
digital city in the world. We have two campuses. Eight
1018
01:02:23.880 --> 01:02:27.519
thousand square meters is the first one, more than one
1019
01:02:27.599 --> 01:02:30.719
hundred square meters for the second one. We have invested
1020
01:02:30.719 --> 01:02:33.159
more than six hundred million euros, which is a lot
1021
01:02:33.159 --> 01:02:37.719
of money. We are welcoming and I am in discussions
1022
01:02:37.760 --> 01:02:44.039
with the owner of this event, with mister Cordeo, because
1023
01:02:44.079 --> 01:02:48.119
I would really love to keep dreaming, and I dare you,
1024
01:02:49.079 --> 01:02:50.639
all of you to keep dreaming.
1025
01:02:50.800 --> 01:02:52.079
I would like to make.
1026
01:02:52.159 --> 01:02:58.760
This city the center of the European longevity world. We
1027
01:02:58.800 --> 01:03:03.079
should think of it. Nothing stops us from thinking and
1028
01:03:03.159 --> 01:03:08.519
from dreaming. So this is our contribution. You were asking before, Louis,
1029
01:03:09.000 --> 01:03:11.960
what is our contribution to this longevity. I am not
1030
01:03:12.039 --> 01:03:14.480
a doctor. I was a Hord student, as I told
1031
01:03:14.480 --> 01:03:18.800
you many times. But we think that putting together private
1032
01:03:18.840 --> 01:03:23.880
and public is fundamental. Dreaming is fundamental. Integrating all stakeholders
1033
01:03:24.400 --> 01:03:28.199
is fundamental. As I said before, we are not in
1034
01:03:28.400 --> 01:03:31.880
heathcare only one. There is no one decision maker. We
1035
01:03:32.000 --> 01:03:36.320
have many in this sector. By bringing them together and
1036
01:03:36.360 --> 01:03:40.199
making them work together, we can improve. This is our
1037
01:03:40.199 --> 01:03:50.800
contribution to longevity. Thank you so much, thank you, thank you, thank.
1038
01:03:50.559 --> 01:03:51.440
You so much.
1039
01:03:51.559 --> 01:03:54.360
And next up we have head of Outreach and Marketing
1040
01:03:54.440 --> 01:03:57.960
at the Coalition for Radical Life Extension, a non for
1041
01:03:58.079 --> 01:04:03.599
profit providing education, resources and community for longevity. So please
1042
01:04:03.639 --> 01:04:05.719
give it up for Marianna Deceellis.
1043
01:04:14.280 --> 01:04:17.760
Thank you. I don't have slights, but I do want
1044
01:04:17.800 --> 01:04:22.000
to address your question, Jusse. Right after we introduce ourselves,
1045
01:04:22.079 --> 01:04:25.320
what can we do to advocate for ourselves or what
1046
01:04:25.360 --> 01:04:29.000
can we do? Do you want to said that question, Joset,
1047
01:04:30.840 --> 01:04:34.599
because I'd really want to answer it. Well, I'd like
1048
01:04:34.679 --> 01:04:41.760
to say, Okay, so I do want to answer that
1049
01:04:41.840 --> 01:04:44.719
question that you gave us, because so, yeah, I told
1050
01:04:44.760 --> 01:04:47.239
you about the Coalition for Radical Life Extension. We spoke
1051
01:04:47.239 --> 01:04:51.400
about RADFAST, the Rally for Longevity Rights. The coalition is
1052
01:04:51.440 --> 01:04:55.519
also has launched this year it's global initiative, and this
1053
01:04:55.639 --> 01:04:59.440
global initiative wants to take radfast and beyond and really
1054
01:04:59.440 --> 01:05:03.760
clearly create the platform for and just bring advocacy and
1055
01:05:03.920 --> 01:05:07.599
breage the gap between policy and people and bringing the
1056
01:05:07.639 --> 01:05:12.360
funding for actually age reversal, not just extending human life span.
1057
01:05:12.760 --> 01:05:17.599
And then I really let's keep it personal here because
1058
01:05:17.639 --> 01:05:21.519
we're all people who here. Whether you feel longevity or
1059
01:05:21.559 --> 01:05:24.760
immortality for yourself, you feel something more. And so I
1060
01:05:24.800 --> 01:05:27.039
want to ask you which one of you feels like
1061
01:05:27.320 --> 01:05:30.719
you have an advocate or are advocating for yourself on
1062
01:05:30.760 --> 01:05:32.880
a daily basis?
1063
01:05:32.880 --> 01:05:33.440
Anybody?
1064
01:05:33.559 --> 01:05:39.920
Nobody? Okay, So doesn't that make you feel a little like, oh,
1065
01:05:40.000 --> 01:05:43.320
I don't have anybody advocating for me today? Am I
1066
01:05:43.360 --> 01:05:47.760
advocating for myself today? And so what we're doing, what
1067
01:05:47.800 --> 01:05:50.199
I'm doing with the Coalition and with people Limited, which
1068
01:05:50.199 --> 01:05:52.920
I feel so proud of, is that we've really brought
1069
01:05:52.960 --> 01:05:56.159
together people like Jose has done that here, we've done
1070
01:05:56.199 --> 01:05:58.719
that in this panel. How you've done the car with
1071
01:05:58.760 --> 01:06:01.920
the clinic and Sarah here and how you've done it
1072
01:06:02.000 --> 01:06:05.320
also encoding as well in all of our panel here.
1073
01:06:05.639 --> 01:06:08.599
It really bring people together to remind ourselves and support
1074
01:06:08.639 --> 01:06:12.639
each other and really are pursuit for this more health?
1075
01:06:13.079 --> 01:06:15.000
And so what is worth?
1076
01:06:15.119 --> 01:06:18.400
What it's longevity if you're not going there with anybody?
1077
01:06:18.559 --> 01:06:18.760
Right?
1078
01:06:19.159 --> 01:06:21.199
And what do we do when we feel we don't
1079
01:06:21.199 --> 01:06:24.760
feel as supportive, we feel sad or we get bad biomarkers?
1080
01:06:24.960 --> 01:06:25.760
Who do you tell?
1081
01:06:26.199 --> 01:06:29.760
And what do you do after the event over here tonight?
1082
01:06:30.440 --> 01:06:33.719
And so because you feel this boost, you feel excited,
1083
01:06:33.760 --> 01:06:36.719
you feel seen. I've seen from ten years of working
1084
01:06:36.800 --> 01:06:40.559
with Radfast and almost twenty with People Limited, I've seen
1085
01:06:41.800 --> 01:06:46.519
researchers and scientists come into that room feeling sad because
1086
01:06:46.519 --> 01:06:50.199
they've been unfunded, they don't feel seen because the research
1087
01:06:50.239 --> 01:06:52.760
feels too out there. And then they come in into
1088
01:06:52.840 --> 01:06:55.480
rooms like this and meet people like you, and then
1089
01:06:55.519 --> 01:06:58.440
they feel seen. They find somebody that will find them
1090
01:06:58.480 --> 01:07:01.880
because maybe I know somebody else, But that only happens
1091
01:07:01.880 --> 01:07:05.400
when we get together. And so really we've heard about
1092
01:07:05.440 --> 01:07:08.039
all of the tools that we talked about. However, said
1093
01:07:08.119 --> 01:07:10.480
let's throw all the tools together. And I really quite
1094
01:07:10.519 --> 01:07:14.199
agree with that, and what are those tools if we're
1095
01:07:14.280 --> 01:07:16.719
not you know, what are we doing with these tools?
1096
01:07:16.760 --> 01:07:20.360
And I really feel that community and spirituality really makes
1097
01:07:20.440 --> 01:07:24.039
sense of those tools, because then other than that, you know,
1098
01:07:24.119 --> 01:07:27.239
they're just tools. And so I feel that community really
1099
01:07:27.320 --> 01:07:29.800
puts together not only the purpose, but what we're doing
1100
01:07:29.880 --> 01:07:31.599
with those that sense.
1101
01:07:33.159 --> 01:07:33.840
What can we do?
1102
01:07:34.199 --> 01:07:34.559
I don't know.
1103
01:07:34.679 --> 01:07:36.480
I think we all have an answer to what we
1104
01:07:36.599 --> 01:07:39.639
can do for longevity. I think we all have very
1105
01:07:39.760 --> 01:07:43.000
valid answers. I think on this Cove has a very
1106
01:07:43.079 --> 01:07:46.880
beautiful answer. I think Clara has very beautiful answers. David
1107
01:07:46.960 --> 01:07:50.119
would present that aful beautiful answers. I think we all
1108
01:07:50.199 --> 01:07:52.880
have very valuable answers to what we can do to
1109
01:07:53.000 --> 01:07:56.719
advocate for super longevity, age reversal, and immortality. But I
1110
01:07:56.800 --> 01:07:59.480
can tell you what you can do for me with
1111
01:07:59.719 --> 01:08:02.199
us so that we can help you. I think you
1112
01:08:02.280 --> 01:08:04.599
need to show up like you have here. We need
1113
01:08:04.679 --> 01:08:06.440
to show up to events like this. We need to
1114
01:08:06.480 --> 01:08:08.679
show up to radfast, we need to show up online,
1115
01:08:08.719 --> 01:08:12.239
we need to show up in person, people Limited needs
1116
01:08:12.400 --> 01:08:16.479
twice a week. I've been meeting twice a week for
1117
01:08:16.640 --> 01:08:20.920
eighteen years with people like you that want this, and
1118
01:08:21.359 --> 01:08:24.119
we meet online or in person. We have people that
1119
01:08:24.319 --> 01:08:27.039
have joined us from all over the world, in Africa
1120
01:08:27.279 --> 01:08:30.800
and Asia and all over and these are all people
1121
01:08:30.960 --> 01:08:33.680
like you who are very passionate and really want to
1122
01:08:33.760 --> 01:08:36.600
see this come through. And so I really invite you
1123
01:08:36.760 --> 01:08:39.640
to show up to come and join me. So for
1124
01:08:39.760 --> 01:08:43.439
people Limited that websites people limited ink dot com, for
1125
01:08:43.920 --> 01:08:48.239
Radfast that's ratfest dot com, for the Global Initiative, and
1126
01:08:48.479 --> 01:08:50.880
what we're doing with the coalition, that's our l E
1127
01:08:51.119 --> 01:08:53.800
Coalition dot com. And if you have any questions you
1128
01:08:53.840 --> 01:08:54.920
can come and ask me.
1129
01:08:55.159 --> 01:09:02.479
Thank you, Marianna.
1130
01:09:02.560 --> 01:09:04.680
I think that was a perfect way to sort of
1131
01:09:04.760 --> 01:09:07.640
show that we need a humane aspect when we also
1132
01:09:07.760 --> 01:09:10.680
talk about longevity, and especially when we talk about advocacy,
1133
01:09:11.199 --> 01:09:13.439
because each and one of us are an advocate for
1134
01:09:13.560 --> 01:09:16.800
our own health, there is a sense of sovereignty needed
1135
01:09:16.960 --> 01:09:18.640
and this can then have ripple effects.
1136
01:09:19.079 --> 01:09:20.279
And I think community and.
1137
01:09:20.399 --> 01:09:24.199
Role models are key because we're talking about health. I mean,
1138
01:09:24.279 --> 01:09:26.960
we've been talking about that since, you know, since the
1139
01:09:27.039 --> 01:09:28.880
Stone Age, because we all want to live healthy, but
1140
01:09:28.920 --> 01:09:31.479
I think we need to have a common vision. Why
1141
01:09:31.600 --> 01:09:35.359
do we want to live a long, healthy life? Well,
1142
01:09:35.399 --> 01:09:38.199
presumably not in the way the world looks today. So
1143
01:09:38.279 --> 01:09:40.720
there's so many factors, and I think community is a
1144
01:09:40.800 --> 01:09:44.439
really important one. Infrastructure is another one. But let's hear
1145
01:09:44.560 --> 01:09:48.079
more from a law speaker, Cody Dean, who is an
1146
01:09:48.199 --> 01:09:53.039
entrepreneur and public voice in immortality and longevity culture, especially
1147
01:09:53.119 --> 01:09:55.800
as content creator for the Immortalists.
1148
01:09:55.840 --> 01:09:57.399
So please give it up for Cody.
1149
01:10:01.840 --> 01:10:02.159
Thank you.
1150
01:10:03.199 --> 01:10:05.760
But I also did not come prepared with slides, so
1151
01:10:05.880 --> 01:10:08.520
I apologize for those of you who are visual. You're
1152
01:10:08.560 --> 01:10:10.439
going to have to just power through and listen. Here.
1153
01:10:11.359 --> 01:10:14.000
I want to address the question that Jose posed earlier
1154
01:10:14.119 --> 01:10:16.439
before we started these presentations of how do we move
1155
01:10:16.520 --> 01:10:20.159
this movement forward? And if you really boil it down,
1156
01:10:20.239 --> 01:10:24.279
there's a challenge of supply and demand, which seems simple enough,
1157
01:10:24.399 --> 01:10:26.760
but how do we break that down a little bit more.
1158
01:10:27.279 --> 01:10:30.840
There's a few aspects to this. There's the problem of science,
1159
01:10:30.960 --> 01:10:34.319
which many of you are working on, so you know
1160
01:10:34.399 --> 01:10:38.000
there's that, But why is science why has it not
1161
01:10:38.279 --> 01:10:40.840
achieved a cure to aging and most of these age
1162
01:10:40.880 --> 01:10:44.079
related diseases yet? Is it just because the science isn't there.
1163
01:10:45.039 --> 01:10:47.960
That's a questionable thing. But if we look a little
1164
01:10:48.000 --> 01:10:52.000
bit further back, there's a challenge of funding, which many
1165
01:10:52.079 --> 01:10:55.319
of you have addressed and asked about and talked about.
1166
01:10:55.720 --> 01:11:00.239
And there's also a challenge of potentially outdated policy and
1167
01:11:00.359 --> 01:11:01.640
politics at play here.
1168
01:11:02.399 --> 01:11:03.119
But if you take.
1169
01:11:03.039 --> 01:11:06.279
Another step back, you can see there's an element of
1170
01:11:07.000 --> 01:11:09.960
this is where the demand comes in. It's people who
1171
01:11:10.159 --> 01:11:12.560
want it. You know, we see this crowd here and
1172
01:11:12.920 --> 01:11:17.319
there's a decent number of people watching live and virtually
1173
01:11:17.399 --> 01:11:20.920
around the world, and you know, up to hundreds of
1174
01:11:20.960 --> 01:11:25.199
people who show up to Radfest and Aubrey's event in Dublin.
1175
01:11:25.520 --> 01:11:29.039
You know, there is a community for this, but the
1176
01:11:29.159 --> 01:11:32.920
demand is not to a level where the voice is
1177
01:11:33.000 --> 01:11:37.319
heard loud enough to affect change on a political and
1178
01:11:37.439 --> 01:11:41.079
policy level. And if that were to happen, if enough
1179
01:11:41.119 --> 01:11:43.199
people were to advocate, and this is where the public
1180
01:11:43.359 --> 01:11:45.960
advocacy comes in, we all need to be louder, we
1181
01:11:46.000 --> 01:11:48.800
all need to talk to more people, and in doing so,
1182
01:11:49.399 --> 01:11:53.560
that voice becomes more unified. I've given an analogy before
1183
01:11:53.640 --> 01:11:57.079
of a symphony. How many people have seen the symphony before?
1184
01:11:57.199 --> 01:11:59.279
Or I at least know what that is, so you
1185
01:11:59.479 --> 01:12:02.399
probably at least know what a symphony is when you
1186
01:12:02.520 --> 01:12:05.000
go to a concert, and if you haven't been, just
1187
01:12:05.119 --> 01:12:08.800
imagine you walk into the auditorium similar to this, and
1188
01:12:08.920 --> 01:12:13.000
down in this area is a large orchestra with lots
1189
01:12:13.039 --> 01:12:17.319
of different instruments, and when you get there early enough,
1190
01:12:17.439 --> 01:12:20.399
you see them all warming up. The conductor is off
1191
01:12:20.479 --> 01:12:23.720
the stage and everyone's warming up their instruments, getting tuned.
1192
01:12:24.239 --> 01:12:26.319
And if you look down and you pay attention to
1193
01:12:26.439 --> 01:12:28.720
the flutes, you can kind of hear what the flutes
1194
01:12:28.760 --> 01:12:31.720
are doing. Their scales is very high pitched, very airy,
1195
01:12:32.399 --> 01:12:35.720
and then there's also a cacophony of sound that's secondary
1196
01:12:35.800 --> 01:12:38.680
behind that because you're focused on the flute section. But
1197
01:12:38.840 --> 01:12:41.640
then you shift your attention over to the French horns
1198
01:12:41.880 --> 01:12:45.680
or the trumpets or whichever other instrument, and now that's
1199
01:12:45.720 --> 01:12:48.159
what you hear. You hear them doing their scales, and
1200
01:12:48.199 --> 01:12:50.439
you hear the tone and the tamera of that instrument,
1201
01:12:51.239 --> 01:12:54.039
and then again just a cacophony of sound that the
1202
01:12:54.079 --> 01:12:56.560
flutes have now blended into. And when you don't focus
1203
01:12:56.640 --> 01:13:00.239
on any instrument, it's just a cacophony of sound. Don't
1204
01:13:00.319 --> 01:13:03.920
really hear any particular thing. But when the director comes
1205
01:13:04.000 --> 01:13:06.000
back out and stands at the front and brings his
1206
01:13:06.119 --> 01:13:09.359
hands up, the entire orchestra comes to attention. And when
1207
01:13:09.600 --> 01:13:12.680
the director moves his hands and the song starts, now
1208
01:13:12.800 --> 01:13:15.680
all of a sudden, you hear a unified piece of
1209
01:13:15.880 --> 01:13:19.680
music and it's beautiful. And that's how we need to
1210
01:13:19.800 --> 01:13:22.640
imagine this community and this movement. We need to come
1211
01:13:22.720 --> 01:13:25.640
together and unify that voice so that way it is
1212
01:13:25.840 --> 01:13:29.399
heard as one song, and that will be beautiful and
1213
01:13:29.520 --> 01:13:33.600
it will be heard by the audience, the policy makers,
1214
01:13:33.680 --> 01:13:37.199
the regulators, the governments around the world, and when it's heard,
1215
01:13:38.359 --> 01:13:41.399
they understand that we as a community, as a people,
1216
01:13:41.600 --> 01:13:44.560
not just a longevity of community, but a human community.
1217
01:13:45.159 --> 01:13:48.079
We are the voter base, so they're going to listen
1218
01:13:48.119 --> 01:13:50.680
to us if they want to keep their jobs. So
1219
01:13:51.279 --> 01:13:56.560
when that happens, policy can be adjusted and streamlined in
1220
01:13:56.760 --> 01:14:01.039
order to maintain safety and efficacy, which we we absolutely need.
1221
01:14:01.239 --> 01:14:05.600
Nobody wants fraudsters coming into this space selling snake oil
1222
01:14:05.720 --> 01:14:07.800
and killing a bunch of people because they want to
1223
01:14:07.840 --> 01:14:10.960
make a bunch of money on longevity. We definitely need
1224
01:14:11.119 --> 01:14:15.439
a standard of safety and efficacy, but we can streamline
1225
01:14:15.479 --> 01:14:19.960
regulation so that we were not holding back beneficial therapies
1226
01:14:20.000 --> 01:14:22.520
for ten to fifteen years that could be saving lives
1227
01:14:22.920 --> 01:14:27.399
much sooner because they can prove themselves much faster. So
1228
01:14:27.479 --> 01:14:31.800
when that policy can be streamlined and adjusted, then investors
1229
01:14:32.159 --> 01:14:35.800
see the potential if they see their potential investment having
1230
01:14:35.840 --> 01:14:39.399
a higher profit margin and having that return come back sooner.
1231
01:14:39.920 --> 01:14:42.000
And that's why in a space like what we're doing
1232
01:14:42.079 --> 01:14:46.279
with Neovia, we want to have a proof of concept
1233
01:14:46.439 --> 01:14:49.840
in a city model first and then of course expand
1234
01:14:49.920 --> 01:14:52.319
from there. We'll have a sister city in South America,
1235
01:14:52.840 --> 01:14:55.880
and then maybe eventually one here in Madrid. You know,
1236
01:14:56.760 --> 01:15:00.399
who knows what the future potential holds there. Even just
1237
01:15:00.439 --> 01:15:04.760
starting with one proof of concept, we see that we
1238
01:15:04.880 --> 01:15:09.479
will see that this streamline regulation is going to speed
1239
01:15:09.600 --> 01:15:12.000
up processes. It's going to make more investment come in.
1240
01:15:12.359 --> 01:15:16.079
But parallel to more money coming in and funding your projects,
1241
01:15:16.239 --> 01:15:18.640
there's also going to be a reduction of the cost
1242
01:15:18.720 --> 01:15:21.800
to go through those trials because there won't be as
1243
01:15:21.920 --> 01:15:25.600
much regulatory red tape to go through, and the regulation
1244
01:15:25.760 --> 01:15:31.319
that is there is actually there to promote safety and efficacy.
1245
01:15:31.479 --> 01:15:36.000
We'll have positive regulation and streamline way through it with
1246
01:15:36.359 --> 01:15:39.840
approval processes that happen as trials are happening, and are
1247
01:15:39.920 --> 01:15:43.920
tailored to each therapy and trial that you're trying to do,
1248
01:15:44.119 --> 01:15:47.319
because in this space there are so many different things
1249
01:15:47.439 --> 01:15:52.119
with genetic editing, with a cellular rejuvenation, with stem cells,
1250
01:15:52.479 --> 01:15:56.000
they all require a different way of looking at it
1251
01:15:56.159 --> 01:16:00.439
and proving it safety and efficacy. That one blanket finition
1252
01:16:00.600 --> 01:16:03.319
of that can't be used to cover everything, and that's
1253
01:16:03.319 --> 01:16:07.439
a big challenge we're running into. So as more funding
1254
01:16:07.560 --> 01:16:09.800
rolls in and as the cost of trials come down,
1255
01:16:10.239 --> 01:16:13.560
then we'll finally reach that point where we're five to
1256
01:16:13.720 --> 01:16:16.560
ten years away or three to five years away from
1257
01:16:16.680 --> 01:16:20.760
having a major breakthrough in curing age related diseases and
1258
01:16:21.399 --> 01:16:25.039
ending humans suffering as a result of that is actually
1259
01:16:25.159 --> 01:16:29.520
going to be three to five years away, as where
1260
01:16:29.920 --> 01:16:32.680
we are now. We've heard three to five years, we've
1261
01:16:32.720 --> 01:16:35.439
heard five to ten years, we've heard ten to twenty years.
1262
01:16:36.000 --> 01:16:38.680
For the last forty or fifty years, we need to
1263
01:16:38.720 --> 01:16:41.079
get to a point where three to five years means
1264
01:16:41.119 --> 01:16:44.920
three to five years on the slow end. We think
1265
01:16:44.960 --> 01:16:48.119
we could make things happen much much faster, and that's
1266
01:16:48.159 --> 01:16:51.159
what we plan on doing. But the major goal is
1267
01:16:51.279 --> 01:16:57.119
to open up the funding opportunities, the investment opportunities, into
1268
01:16:57.279 --> 01:17:01.479
your scientific community, into the trial as you are doing again,
1269
01:17:01.600 --> 01:17:04.560
like I said earlier, because selfishly, I want to live
1270
01:17:04.680 --> 01:17:06.600
and I want to be healthy. I don't want to
1271
01:17:06.640 --> 01:17:10.439
grow up older and then die from being sick or
1272
01:17:10.560 --> 01:17:14.159
just getting old. Because we're just dealing with the things
1273
01:17:14.199 --> 01:17:17.279
we're dealing with now. So how do we move this
1274
01:17:17.439 --> 01:17:20.920
movement forward? To break it down to the most simple thing,
1275
01:17:21.640 --> 01:17:26.720
advocate talk to people that demand will through as I
1276
01:17:26.880 --> 01:17:30.199
just discussed, hit all the different points where finally the
1277
01:17:30.319 --> 01:17:32.279
supply will have to be there.
1278
01:17:33.279 --> 01:17:44.079
Thank you, Thank you to all of you great advocates.
1279
01:17:44.359 --> 01:17:47.199
Does anyone have any questions when it comes to advocacy
1280
01:17:47.239 --> 01:17:50.079
because this is actually a topic that relates to each
1281
01:17:50.159 --> 01:17:53.359
and every one of us, so you know, no questions
1282
01:17:53.439 --> 01:17:54.239
are too small.
1283
01:17:57.800 --> 01:18:00.119
Oh you know, could we just have a short does
1284
01:18:00.279 --> 01:18:01.840
mad what the question was in English?
1285
01:18:02.439 --> 01:18:04.279
So maybe the audience not I one in Spanish?
1286
01:18:07.479 --> 01:18:12.079
I think I think you were asking about that all
1287
01:18:12.159 --> 01:18:13.680
tel question on whether.
1288
01:18:13.720 --> 01:18:14.600
You know what happens?
1289
01:18:15.439 --> 01:18:18.319
You know, do you distribute money first to guns or
1290
01:18:18.399 --> 01:18:21.840
do they go to fiting? And how do we and
1291
01:18:22.359 --> 01:18:24.319
what are kind of alliances are we going to make
1292
01:18:24.319 --> 01:18:27.039
sure to make so that we know that that money's
1293
01:18:27.079 --> 01:18:27.760
been distributed?
1294
01:18:27.840 --> 01:18:28.000
Right?
1295
01:18:29.000 --> 01:18:32.119
If I can take that question first, I will say,
1296
01:18:32.840 --> 01:18:35.680
until we solve aging, there's always going to be worse.
1297
01:18:36.520 --> 01:18:38.800
I mean, I think there's always going to be death.
1298
01:18:38.960 --> 01:18:42.039
But once we cure aging, there's going to be a
1299
01:18:42.119 --> 01:18:44.800
huge culture shift. I mean, we're looking at the biggest
1300
01:18:44.920 --> 01:18:50.439
paradigm shift we've ever seen has humanity. And unfortunately people
1301
01:18:50.560 --> 01:18:53.359
see death like part of a circle. That's not how
1302
01:18:53.439 --> 01:18:56.640
I feel, that's not what I see. I feel differently.
1303
01:18:56.760 --> 01:18:59.880
But once we cure death and the diseases of aging,
1304
01:19:00.119 --> 01:19:03.239
the whole paradigm that we've known so far as humans
1305
01:19:03.279 --> 01:19:05.920
and culture are completely going to change. So the question
1306
01:19:06.039 --> 01:19:09.039
we posed so far and the way we've treated each
1307
01:19:09.079 --> 01:19:12.000
other so far are going to change. Because if you're
1308
01:19:12.079 --> 01:19:14.960
not just getting rid of ten years worth of living
1309
01:19:15.039 --> 01:19:17.720
of a human, you're getting rid of five hundred years.
1310
01:19:18.319 --> 01:19:23.439
So yeah, hopefully we're expanding our consciousness and seeing other
1311
01:19:23.520 --> 01:19:26.520
things worthwhile than what we've seen in the last decade
1312
01:19:26.560 --> 01:19:28.800
of man hurting man.
1313
01:19:28.960 --> 01:19:32.960
Yes, actually Spanish scientists who got the Nobel Price and
1314
01:19:33.039 --> 01:19:37.199
Teago Ramonica help so he gave classes here. By the way,
1315
01:19:37.479 --> 01:19:41.880
Santiago Ramonica Hall lectured here our first Nobel prize in
1316
01:19:42.960 --> 01:19:46.199
nineteen o six or something like that.
1317
01:19:46.520 --> 01:19:47.960
I was not born at the time.
1318
01:19:48.399 --> 01:19:49.000
There we have one.
1319
01:19:49.640 --> 01:19:52.600
I think you have to make a ratio between how
1320
01:19:52.720 --> 01:19:57.680
much money is spent in health and in weapons per
1321
01:19:57.840 --> 01:20:02.640
year for Washington and the radio property is going to
1322
01:20:02.760 --> 01:20:07.079
be two minutes of defense expenditure in one year is
1323
01:20:07.159 --> 01:20:08.439
less than what we're spending here.
1324
01:20:08.960 --> 01:20:11.439
Yeah, we need the politicians at the table so we
1325
01:20:11.520 --> 01:20:12.800
can ask that question.
1326
01:20:14.159 --> 01:20:14.680
Marianna.
1327
01:20:14.920 --> 01:20:18.479
Since you are organized in the march, they're running in Washington,
1328
01:20:18.600 --> 01:20:21.399
d see, what are you going to tell President Trump.
1329
01:20:24.199 --> 01:20:24.800
I'm not going to.
1330
01:20:24.800 --> 01:20:28.640
Answer that, but I will answer is that the march
1331
01:20:28.840 --> 01:20:33.479
is focusing on longevity rights because we don't want this
1332
01:20:33.680 --> 01:20:35.760
to be something that can be used against us.
1333
01:20:35.840 --> 01:20:38.159
We spoke about safety and security before.
1334
01:20:38.640 --> 01:20:40.720
So one of the biggest focus of the Coalition and
1335
01:20:40.800 --> 01:20:43.640
the March is going to be to really make this
1336
01:20:44.000 --> 01:20:47.359
about everybody and not just about longevity and immortality, but
1337
01:20:47.520 --> 01:20:50.119
really about all of us being able to get access
1338
01:20:50.199 --> 01:20:52.479
to all of this medicine. And we feel that that
1339
01:20:52.600 --> 01:20:55.039
it will be the first door to open and then
1340
01:20:55.079 --> 01:20:57.039
all of this will be because I also have the
1341
01:20:57.159 --> 01:21:00.479
same concerns as we do. So I'm glad you're putting
1342
01:21:00.520 --> 01:21:01.000
that out there.
1343
01:21:02.840 --> 01:21:03.680
Any more questions.
1344
01:21:04.920 --> 01:21:07.079
I mean, all of you are are advocates, So if
1345
01:21:07.119 --> 01:21:10.119
we would sort of summarize and maybe hand the tool
1346
01:21:10.199 --> 01:21:11.800
of advocacy to people.
1347
01:21:11.680 --> 01:21:14.720
Here, if you could each share, you know, your own sort.
1348
01:21:14.520 --> 01:21:18.439
Of nugget on advocacy. How do how do we create
1349
01:21:18.479 --> 01:21:22.760
a narrative around longevity? I mean some say immortality, some
1350
01:21:22.960 --> 01:21:27.239
say radical life extensions, some say hell, some say living forever.
1351
01:21:27.680 --> 01:21:30.880
You know, if we're going to unify this advocacy, if
1352
01:21:30.960 --> 01:21:31.279
each and.
1353
01:21:31.319 --> 01:21:34.199
Every one of you know, did you have like a tagline,
1354
01:21:34.640 --> 01:21:36.920
and then we can get some inspiration when it comes
1355
01:21:37.000 --> 01:21:41.279
to longevity or eternal living, flourishing.
1356
01:21:40.960 --> 01:21:42.640
Joy, spam, whatever it might be.
1357
01:21:44.119 --> 01:21:44.319
Yeah.
1358
01:21:44.520 --> 01:21:46.840
Well, to finish, I'm going to be a little bit
1359
01:21:46.960 --> 01:21:47.640
more general.
1360
01:21:47.960 --> 01:21:53.000
So my main advice I cannot avoid to give advices
1361
01:21:53.039 --> 01:21:56.520
because I'm mother for two daughters and one son, and
1362
01:21:56.680 --> 01:21:58.640
I used to do advices.
1363
01:21:59.319 --> 01:22:03.600
So my many advice is to support science and to
1364
01:22:03.720 --> 01:22:05.560
pay attention to scientists.
1365
01:22:05.640 --> 01:22:10.039
It's very important to have critical thinking talking about longevity,
1366
01:22:10.199 --> 01:22:13.800
about health, about many other things. We pay attention to
1367
01:22:14.720 --> 01:22:21.119
people that really don't give advices support it by science data.
1368
01:22:21.319 --> 01:22:24.880
So this is very important to develop the critical thinking.
1369
01:22:25.399 --> 01:22:28.800
So this is one of my first advices. The other
1370
01:22:28.920 --> 01:22:33.359
one is as a citizen, we can really support companies
1371
01:22:33.600 --> 01:22:36.960
that support science instead many other things like.
1372
01:22:37.000 --> 01:22:37.880
Weapons or whatever.
1373
01:22:38.479 --> 01:22:42.279
So we should develop also our critical thinking to see
1374
01:22:42.880 --> 01:22:48.600
which companies we like and we don't, So this is important.
1375
01:22:48.640 --> 01:22:52.479
And for the companies, I will advise you to use
1376
01:22:52.640 --> 01:22:57.960
your responsibility to support science for example through a patinal,
1377
01:22:58.000 --> 01:23:01.840
a TENTFIA and as a citizens also I mean something
1378
01:23:01.920 --> 01:23:04.920
that we want to be to be.
1379
01:23:05.039 --> 01:23:10.079
Happy, to be healthy and happy. And one that of
1380
01:23:10.199 --> 01:23:13.439
the things that make us very happy is the generosity.
1381
01:23:13.960 --> 01:23:16.800
So when you find a course, you find a purpose
1382
01:23:16.880 --> 01:23:21.079
in your life and you really support it by a
1383
01:23:21.159 --> 01:23:24.239
donation or by a collaboration with it. So we are
1384
01:23:24.399 --> 01:23:29.239
here to have you. You are happy and finally you
1385
01:23:29.399 --> 01:23:32.439
are you are better in life.
1386
01:23:32.640 --> 01:23:36.720
So please I hope many of you find a paternal
1387
01:23:36.760 --> 01:23:41.199
athenia a good way to really put your donation or
1388
01:23:41.279 --> 01:23:44.520
do your collaboration to support science that finally is going
1389
01:23:44.600 --> 01:23:45.359
to impact in.
1390
01:23:45.560 --> 01:23:46.600
All our lives.
1391
01:23:47.079 --> 01:23:50.479
And also you have the possibility to reduce the taxes
1392
01:23:50.560 --> 01:23:52.439
because a parentalth Infia.
1393
01:23:52.600 --> 01:23:57.960
Got the position of Tilda public. So please you are
1394
01:23:58.000 --> 01:24:01.560
welcome to come to visitors. I think, thank you.
1395
01:24:02.039 --> 01:24:02.600
I just want to.
1396
01:24:02.600 --> 01:24:05.840
Support her idea. It's the law of life is really
1397
01:24:05.880 --> 01:24:09.079
what defines the community. We love life so deeply, we
1398
01:24:09.279 --> 01:24:11.760
really want to extend it. We find it extremely unfair,
1399
01:24:12.520 --> 01:24:13.479
and I think.
1400
01:24:13.319 --> 01:24:16.079
It's not hard to drive this feeling into everyone.
1401
01:24:16.600 --> 01:24:19.399
We really I think that the problem is most people have.
1402
01:24:19.479 --> 01:24:22.880
Not heard that this is even possible. Honestly, most people
1403
01:24:22.960 --> 01:24:25.760
that I talk about it with and just regular people,
1404
01:24:25.800 --> 01:24:30.239
most people are supportive of life extension. And I think
1405
01:24:30.279 --> 01:24:32.640
it's more of a marketing and a media effort. And
1406
01:24:32.720 --> 01:24:36.960
as soon as we all everybody realizes life is so valuable,
1407
01:24:37.039 --> 01:24:39.359
so important that who wants to kill each other to
1408
01:24:39.439 --> 01:24:43.720
have arguments, to have fights to discuss silly political part
1409
01:24:43.760 --> 01:24:45.680
also the trend of the right and the left, and
1410
01:24:46.680 --> 01:24:48.600
so we're so sick of it that we have to
1411
01:24:48.680 --> 01:24:52.880
move past this period. It's really annoying and frustrating that
1412
01:24:53.439 --> 01:24:56.399
the debates are not more more enlivening.
1413
01:24:57.720 --> 01:25:00.319
There needs to be a mirroring the weapon here in
1414
01:25:00.399 --> 01:25:02.880
health here, and there's a mirror because everybody wants initially
1415
01:25:02.960 --> 01:25:05.479
what you're saying, But we're living in a world where fear.
1416
01:25:05.279 --> 01:25:07.800
And scarcity is but nobody knows what transhuman is.
1417
01:25:07.840 --> 01:25:08.159
Amiss.
1418
01:25:08.239 --> 01:25:08.439
Yeah.
1419
01:25:11.000 --> 01:25:13.399
On a similar tone, I don't tend to speak to
1420
01:25:13.479 --> 01:25:17.960
my patients about immortality, but I always try to ask
1421
01:25:18.039 --> 01:25:21.319
them like, do you want to die tomorrow? They usually
1422
01:25:21.359 --> 01:25:24.840
say no, and then it comes like what makes you
1423
01:25:24.960 --> 01:25:28.279
think that you will want to die someday if you're
1424
01:25:28.279 --> 01:25:31.560
a great health. So I think that for the general
1425
01:25:31.640 --> 01:25:35.600
society talking about infinity immortality, it's just like concepts. They
1426
01:25:35.640 --> 01:25:37.960
can really grass no exactly, but when they put it
1427
01:25:38.039 --> 01:25:41.640
into the perspective of today, no one wants to die tomorrow,
1428
01:25:42.079 --> 01:25:44.199
and eventually that means that you don't want to die
1429
01:25:44.239 --> 01:25:46.800
at some point if you're in great health. And as
1430
01:25:46.800 --> 01:25:49.119
we're talking about advocacy and I don't want to extend
1431
01:25:49.119 --> 01:25:51.319
because I know it's too long, I would love to
1432
01:25:51.359 --> 01:25:54.279
make a small remark, especially going back to the science part,
1433
01:25:54.800 --> 01:25:58.680
that we need to do more research on female longevity definitely.
1434
01:25:59.039 --> 01:26:05.960
So it's if longevity has little funding, female longevity as
1435
01:26:06.079 --> 01:26:10.840
lost to none and women age differently than men exactly.
1436
01:26:10.880 --> 01:26:12.119
So as an.
1437
01:26:12.039 --> 01:26:15.119
Advocate and having a microphone in my hand. This fun
1438
01:26:15.279 --> 01:26:17.520
female research, female angevity research.
1439
01:26:19.560 --> 01:26:23.199
And to add to that, there is something in the making,
1440
01:26:23.560 --> 01:26:26.319
the launch of Superwoman, which is going to be dedicated
1441
01:26:26.439 --> 01:26:29.159
just to that. So I'm really getting all the women
1442
01:26:29.239 --> 01:26:32.239
I can find to get together and make that happen.
1443
01:26:32.439 --> 01:26:36.039
As I said before, we need to keep pushting, developing
1444
01:26:36.359 --> 01:26:40.640
and fostering public and private collaboration because we need a
1445
01:26:40.680 --> 01:26:43.760
better system that prevents, not just cares what prevents.
1446
01:26:45.000 --> 01:26:45.319
Thank you.
1447
01:26:46.119 --> 01:26:50.000
I think we cannot be afraid of spirituality and the
1448
01:26:50.079 --> 01:26:52.279
divinity of the body, and we need to remind each
1449
01:26:52.319 --> 01:26:54.920
other of that. I think that when people think of
1450
01:26:55.039 --> 01:26:57.279
cure and aging, they think you're trying to play God.
1451
01:26:57.479 --> 01:26:59.720
And I don't see anything wrong with that statement.
1452
01:26:59.840 --> 01:27:02.600
I think we are and I think we all here.
1453
01:27:03.039 --> 01:27:05.119
Of something in common, and it's that we do all
1454
01:27:05.239 --> 01:27:08.800
feel the value of human life, of our bodies and
1455
01:27:08.960 --> 01:27:13.119
some other people's bodies that we've lost, and so for
1456
01:27:13.640 --> 01:27:16.000
all of us to not forget why we're doing this,
1457
01:27:16.159 --> 01:27:18.720
and it really is the celebration of the divinity of
1458
01:27:18.800 --> 01:27:19.199
the body.
1459
01:27:20.000 --> 01:27:20.359
Thank you.
1460
01:27:21.960 --> 01:27:25.319
To go back to the original question of immortality versus
1461
01:27:25.520 --> 01:27:28.520
radical life, extension versus longevity, and how do we combine
1462
01:27:28.600 --> 01:27:32.159
all of that. To me, the common denominator is do
1463
01:27:32.359 --> 01:27:36.439
you want to live healthier, longer period. If the answer
1464
01:27:36.520 --> 01:27:38.920
is yes, you're a part of this community. After that,
1465
01:27:39.199 --> 01:27:41.960
it's a personal choice on the individual level of how
1466
01:27:42.079 --> 01:27:42.960
much longer.
1467
01:27:42.760 --> 01:27:46.279
Do you want? And I really think, you know, I
1468
01:27:46.399 --> 01:27:48.600
think that the purpose is also we need to find
1469
01:27:48.680 --> 01:27:51.399
purpose and meaning in our own lives and in sort
1470
01:27:51.399 --> 01:27:53.920
of the life in general. And I think when we
1471
01:27:54.039 --> 01:27:57.680
start to navigate, whether it's spirituality, divinity, I mean, these
1472
01:27:57.880 --> 01:28:00.600
concepts are getting much more into the life now. A
1473
01:28:00.640 --> 01:28:02.560
few years ago when you spoke about this, it was
1474
01:28:02.600 --> 01:28:04.720
a bit woo woo, but this is actually, you know,
1475
01:28:05.119 --> 01:28:08.000
self evolvement. We're here for a great adventure called life.
1476
01:28:08.079 --> 01:28:10.720
Of course, we want to live, enjoy and happiness, but
1477
01:28:10.840 --> 01:28:13.039
we also need to be sovereign and start to maybe
1478
01:28:13.119 --> 01:28:13.640
demand that.
1479
01:28:13.800 --> 01:28:15.880
And it comes from you know, the people.
1480
01:28:16.359 --> 01:28:20.960
And longevity is an amazing, amazing, you know occurrence that
1481
01:28:21.079 --> 01:28:25.319
it's happened now because advocacy has never been stronger, because
1482
01:28:25.359 --> 01:28:27.920
people are voicing up. The science is there, and I
1483
01:28:28.000 --> 01:28:29.760
think it's going to you know, accelerate more and more
1484
01:28:30.000 --> 01:28:31.000
thanks to people like you.
1485
01:28:31.199 --> 01:28:33.319
So round of applause for all of our advocates.
1486
01:28:33.359 --> 01:28:34.319
A leader is thank you.
1487
01:28:38.960 --> 01:28:39.319
Thank you.
1488
01:28:43.720 --> 01:28:49.239
So with that, ladies and gentlemen and advocates of longevity
1489
01:28:49.279 --> 01:28:54.159
and pioneers, our final keynote speaker is truly a pioneer herself,
1490
01:28:54.279 --> 01:28:57.560
both as a leader how she came into the longevity space,
1491
01:28:57.880 --> 01:29:00.800
which many times happen because you have a person issue
1492
01:29:00.880 --> 01:29:03.359
with which she had with her son. But she's a
1493
01:29:03.439 --> 01:29:06.680
pioneer within gene therapy and one of the boldest voices
1494
01:29:06.760 --> 01:29:09.560
in the field as well, because she allows also to
1495
01:29:09.680 --> 01:29:10.600
be provocative.
1496
01:29:10.960 --> 01:29:12.720
Not Lisa's gene therapy.
1497
01:29:12.720 --> 01:29:15.520
As we know, is not accessible, but she's really traveling
1498
01:29:15.880 --> 01:29:19.600
the globe around to really make this accessible in certain
1499
01:29:19.640 --> 01:29:22.640
parts of the world. She's the founder and CEO of Bioviva,
1500
01:29:23.000 --> 01:29:27.319
a driven humanitarian entrepreneur and a leading voice for genetic cures,
1501
01:29:27.600 --> 01:29:32.159
and she's championing gene therapies as a path to human rejuvenation.
1502
01:29:32.479 --> 01:29:34.760
And here we can talk about human trials because she
1503
01:29:35.439 --> 01:29:38.399
is doing this on herself. Please give it up if
1504
01:29:38.439 --> 01:29:41.359
she's with us, Liz perish.
1505
01:29:42.640 --> 01:29:49.479
Hopefully, Okay, fantastic.
1506
01:29:49.680 --> 01:29:52.279
It's nice to be here everyone, and so let me
1507
01:29:52.359 --> 01:29:53.520
get my slides ready.
1508
01:29:54.279 --> 01:29:59.359
I have the Hi Jose how are you awesome?
1509
01:30:00.000 --> 01:30:03.159
I just okay, great, I can share my slides. It
1510
01:30:03.239 --> 01:30:06.920
looks like and so we'll get on that. I hope
1511
01:30:06.960 --> 01:30:09.560
everyone's enjoying the conference. It looks like you guys had
1512
01:30:09.600 --> 01:30:15.600
a terrific March two for the Death of Death, so
1513
01:30:15.960 --> 01:30:20.840
fantastic and congratulations on that. Okay, fantastic. So we're going
1514
01:30:20.920 --> 01:30:23.720
to talk about the evolution of gene therapy, where we've
1515
01:30:23.800 --> 01:30:24.119
been and.
1516
01:30:24.159 --> 01:30:25.079
Where we are going.
1517
01:30:25.760 --> 01:30:28.000
As you know, Bioviva has had a little bit of
1518
01:30:28.079 --> 01:30:34.119
a rocky road this year because of what's called hands
1519
01:30:34.239 --> 01:30:35.079
off research.
1520
01:30:36.479 --> 01:30:36.640
Hi.
1521
01:30:38.399 --> 01:30:42.479
I can see everyone in the audience. Hey, everyone, whoo,
1522
01:30:43.279 --> 01:30:45.760
shake it up, get your body moving. I know it's
1523
01:30:46.119 --> 01:30:48.479
evening for you, but it's early in the morning for me.
1524
01:30:49.159 --> 01:30:55.880
You guys all look fantastic, So let me proceed in
1525
01:30:56.039 --> 01:30:58.399
hands off research. What we do is we pay a
1526
01:30:58.560 --> 01:31:02.239
university to do research, and then sometimes there are things
1527
01:31:02.319 --> 01:31:07.239
called detractors, and sometimes there are things called missteps in science.
1528
01:31:07.720 --> 01:31:10.119
And right now we have a paper that's under review
1529
01:31:10.319 --> 01:31:11.039
for just that.
1530
01:31:11.479 --> 01:31:13.760
And I imagine the infernos.
1531
01:31:13.199 --> 01:31:17.000
Of hell are going to be burning bright in the
1532
01:31:17.119 --> 01:31:20.399
near future for one side or the other. So we
1533
01:31:20.520 --> 01:31:23.960
can't talk too much about that today because that's under investigation.
1534
01:31:24.800 --> 01:31:28.479
But I'll let you know that our company is dedicated
1535
01:31:28.600 --> 01:31:32.960
to science and science working for humans. We are translational
1536
01:31:33.079 --> 01:31:35.960
engine and that's what we're going to get into today.
1537
01:31:36.399 --> 01:31:39.960
If science can't translate to humans, then we are all
1538
01:31:40.159 --> 01:31:42.960
going to die. And I'm going to show you how
1539
01:31:43.119 --> 01:31:46.079
we have proven that science has already translated and that
1540
01:31:46.159 --> 01:31:47.119
we can build upon it.
1541
01:31:47.840 --> 01:31:49.720
But if we are detracted from.
1542
01:31:49.840 --> 01:31:53.640
And science is blocked, that would be the responsibility of
1543
01:31:53.680 --> 01:31:55.119
the murder of millions of people.
1544
01:31:55.520 --> 01:31:58.159
And so we also have to watch that side of
1545
01:31:58.279 --> 01:31:58.760
the aisle.
1546
01:32:00.159 --> 01:32:04.760
Let's get into an exciting presentation in which I think
1547
01:32:04.840 --> 01:32:05.560
you can all.
1548
01:32:05.520 --> 01:32:07.399
Agree we need the cure aging.
1549
01:32:08.680 --> 01:32:11.640
So we're going to go back really quick historically into
1550
01:32:11.760 --> 01:32:13.439
the death records of humans.
1551
01:32:13.560 --> 01:32:15.600
And this is because I want to show you that
1552
01:32:15.760 --> 01:32:17.520
science is already working.
1553
01:32:17.800 --> 01:32:24.039
We have basically elucidated many different scientific advances to extend
1554
01:32:24.159 --> 01:32:25.479
human lifespan.
1555
01:32:25.399 --> 01:32:27.359
And these records are evidence of that.
1556
01:32:27.960 --> 01:32:32.000
So in sixteen sixty five, we vastly died of infectious disease,
1557
01:32:32.640 --> 01:32:35.439
and because we took it so seriously, by the year
1558
01:32:35.600 --> 01:32:39.039
of nineteen hundred, we got that infectious disease rate down
1559
01:32:39.119 --> 01:32:41.920
to almost fifty percent of the population. And that was
1560
01:32:42.000 --> 01:32:46.359
because we used science, a technology that's rigorous that tests
1561
01:32:46.479 --> 01:32:51.359
whether or not something will work to circumvent maybe in
1562
01:32:51.479 --> 01:32:55.439
this case, a death outcome. And this is fantastic because
1563
01:32:55.520 --> 01:32:58.479
this made it so that we could live longer and healthier.
1564
01:32:59.000 --> 01:33:03.680
But if you notice graph, we start to see the.
1565
01:33:03.800 --> 01:33:07.960
Expansion of diseases that we didn't have on the original graph,
1566
01:33:08.199 --> 01:33:10.119
and that is because we started to.
1567
01:33:11.039 --> 01:33:13.880
Name aging associate diseases.
1568
01:33:14.239 --> 01:33:17.680
So by the year twenty ten, only three percent of
1569
01:33:17.760 --> 01:33:20.359
the population is dying of infectious disease.
1570
01:33:20.720 --> 01:33:21.760
And this is science.
1571
01:33:21.920 --> 01:33:26.199
This is science showing that already it's working on life expansion.
1572
01:33:26.319 --> 01:33:30.920
So longevity science started way back, probably around the eighteen
1573
01:33:31.039 --> 01:33:34.920
hundreds and has advanced beautifully since then. So if people
1574
01:33:35.039 --> 01:33:39.720
say that it is science fiction to extend lifespan, actually
1575
01:33:40.199 --> 01:33:43.119
most of the population has already benefited from that.
1576
01:33:44.560 --> 01:33:45.680
So when we look at.
1577
01:33:45.600 --> 01:33:48.840
Old medicine, we looked at symptom management, and we still
1578
01:33:48.920 --> 01:33:52.079
have a lot of this, mostly in the healthcare system,
1579
01:33:52.600 --> 01:33:55.720
not so much in medical tourism. But we do what's
1580
01:33:55.760 --> 01:34:00.399
called symptom management, and we use tools and we look
1581
01:34:00.439 --> 01:34:02.960
at herbal remedies and natural things that we can do,
1582
01:34:03.520 --> 01:34:06.800
and this is really still where diet and exercise lies.
1583
01:34:07.039 --> 01:34:09.680
It's powerful technology and you can see that it got
1584
01:34:09.800 --> 01:34:13.239
us a long ways. Then as we advanced, we worked
1585
01:34:13.279 --> 01:34:17.119
into diagnostics. How did we actually diagnose something before it
1586
01:34:17.319 --> 01:34:20.560
happened instead of waiting for it to happen, And this
1587
01:34:20.920 --> 01:34:24.239
really opened the realm of regeederative medicine to step in.
1588
01:34:24.479 --> 01:34:28.319
And that is really the third stage, which is using
1589
01:34:28.399 --> 01:34:32.239
regenerative medicine to create a cell that stays in homeostasis,
1590
01:34:32.880 --> 01:34:37.399
that ages as slowly as possible, or maybe even reversus aging.
1591
01:34:37.920 --> 01:34:39.680
So I'm going to talk about.
1592
01:34:39.600 --> 01:34:43.479
Our modalities of how we work, and we work at
1593
01:34:43.560 --> 01:34:48.920
Bioviva in genetics and in gene therapy. So our mission
1594
01:34:49.159 --> 01:34:52.680
is to find gene therapies that will modulate the aging
1595
01:34:52.800 --> 01:34:56.560
process and keep the body in homeostasis. How I became
1596
01:34:56.680 --> 01:35:00.720
a GMO and why I think you will too was
1597
01:35:00.800 --> 01:35:03.760
a long journey that I've had over twelve years in
1598
01:35:03.840 --> 01:35:07.880
regenerative medicine in ten years with the company Bioviva, and
1599
01:35:08.399 --> 01:35:11.680
the evidence that we've shown that probably actually working with
1600
01:35:11.920 --> 01:35:14.800
genetic therapeutics is the best way to move forward for
1601
01:35:14.920 --> 01:35:18.199
most of the population because then you can set a
1602
01:35:18.319 --> 01:35:22.359
lot of your biological aging therapies and forget them at
1603
01:35:22.439 --> 01:35:24.479
least for ten to fifteen years.
1604
01:35:24.680 --> 01:35:26.880
And that's an unimaginably powerful tool.
1605
01:35:27.079 --> 01:35:30.359
We will probably need other tools alongside this technology, and
1606
01:35:30.439 --> 01:35:33.760
we'll talk about those as we go. So why I
1607
01:35:33.920 --> 01:35:37.359
became a GMO is I was working regenerative medicine for
1608
01:35:37.439 --> 01:35:40.239
two years and my son was diagnosed with type one
1609
01:35:40.319 --> 01:35:42.319
diabetes in twenty thirteen.
1610
01:35:43.159 --> 01:35:45.640
So after working in the regenerative medicine.
1611
01:35:45.239 --> 01:35:48.039
Space, I thought that once I ended up in the
1612
01:35:48.079 --> 01:35:52.279
hospital or a loved one did, that this regenerative medicine
1613
01:35:52.319 --> 01:35:55.399
technology would be available for us, that we would not
1614
01:35:55.680 --> 01:35:58.560
be fighting diseases with palliative care.
1615
01:35:59.199 --> 01:36:00.680
But in fact I was wrong.
1616
01:36:01.000 --> 01:36:04.880
This type of technology was not translating quickly, not quickly
1617
01:36:05.039 --> 01:36:07.720
enough for most patients on the hills of Going to
1618
01:36:07.840 --> 01:36:11.520
a SENSE conference later that year to meet the professor
1619
01:36:11.560 --> 01:36:14.680
of genetics at Harvard, George Church, which eventually joined the
1620
01:36:14.760 --> 01:36:17.960
company as a founder, I found out that by treating
1621
01:36:18.039 --> 01:36:23.680
biological aging and treating the genetic basis of biological aging,
1622
01:36:23.760 --> 01:36:26.760
we could actually expedite cures for these kids. And so
1623
01:36:27.159 --> 01:36:30.199
my company, Bioviva, every gene we have chosen since then
1624
01:36:30.279 --> 01:36:33.239
will actually treat both ends of the spectrum, so the
1625
01:36:33.399 --> 01:36:37.760
aging population and the young population, basically taking care of
1626
01:36:37.840 --> 01:36:39.840
the critical care for the most.
1627
01:36:39.760 --> 01:36:41.960
Vulnerable populations on the planet.
1628
01:36:43.199 --> 01:36:46.680
And why do we need to do that because both
1629
01:36:47.439 --> 01:36:52.000
vulnerable ends of the population drain a lot in resources.
1630
01:36:52.159 --> 01:36:53.399
So when you're young, you.
1631
01:36:53.439 --> 01:36:56.439
Don't have a job, makes sense, society pays for you
1632
01:36:56.720 --> 01:36:59.760
to grow up. Then you're in your earning stages, in
1633
01:36:59.800 --> 01:37:03.079
wh you are profitable in the sense that you're above
1634
01:37:03.199 --> 01:37:07.000
what it costs to live, and then as you age, unfortunately,
1635
01:37:07.119 --> 01:37:10.159
you fall back below this line. And this is really
1636
01:37:10.279 --> 01:37:14.279
critical because many people who are in this age group
1637
01:37:14.319 --> 01:37:17.159
of around fifty five still have dreams.
1638
01:37:17.239 --> 01:37:20.199
There are still things they want to do. But these
1639
01:37:20.439 --> 01:37:22.800
estimates in earning versus.
1640
01:37:22.640 --> 01:37:25.279
Eating would tell us that your dreams are over and
1641
01:37:25.439 --> 01:37:29.800
you better breaks for the future of really high costs
1642
01:37:29.920 --> 01:37:30.600
and healthcare.
1643
01:37:31.479 --> 01:37:34.159
We want to change that. So what does that look like.
1644
01:37:34.319 --> 01:37:37.600
Let's go back to sixteen sixty five. Infectious disease. You're
1645
01:37:37.640 --> 01:37:40.479
going along, you get an infectious disease, you die fast.
1646
01:37:41.840 --> 01:37:44.399
The middle graph is what happens today. That is the
1647
01:37:44.479 --> 01:37:48.600
death curve, the slow death curve, and decline into in
1648
01:37:48.760 --> 01:37:52.119
stage diseases, and what happens is you get a symptom
1649
01:37:52.640 --> 01:37:56.000
and then we try to recover you with today's medicine,
1650
01:37:56.079 --> 01:37:58.960
but generally we put you back on the death curve
1651
01:37:59.560 --> 01:38:03.039
and your health continues to decline, but you continue to
1652
01:38:03.239 --> 01:38:06.319
consume these drugs that at least keep you alive. The
1653
01:38:06.439 --> 01:38:09.479
graph on the right we call tomorrow's medicine, but it's
1654
01:38:09.520 --> 01:38:13.880
already started about ten years ago when we started. And
1655
01:38:14.439 --> 01:38:19.079
this is what happens when we look at genetics, the
1656
01:38:19.199 --> 01:38:23.520
ability to potentially restore the body to a healthy state.
1657
01:38:23.680 --> 01:38:26.600
I was just at Harvard with David Sinclair a couple
1658
01:38:26.600 --> 01:38:30.039
of days ago, and he has amazing research also going
1659
01:38:30.119 --> 01:38:32.840
on in gene therapy. Some of the things that we
1660
01:38:33.119 --> 01:38:37.399
do it bio viva as well, and incorporating all of
1661
01:38:37.479 --> 01:38:42.159
these things looks incredibly promising to maybe deliver on this
1662
01:38:42.359 --> 01:38:43.279
graph that I'm showing you.
1663
01:38:44.000 --> 01:38:45.960
So what is gene therapy.
1664
01:38:46.279 --> 01:38:49.960
With gene therapy today, we use AAV It's a deno
1665
01:38:50.039 --> 01:38:53.640
associate virus. It is what used to be a virus
1666
01:38:53.720 --> 01:38:56.319
and it's now attenuated and called a vector.
1667
01:38:56.439 --> 01:38:58.079
It can no longer get you sick.
1668
01:38:58.800 --> 01:39:02.439
But what's really great about these vectors is nature has
1669
01:39:02.520 --> 01:39:07.560
designed them eloquently to deliver to your cell's genetic material
1670
01:39:07.680 --> 01:39:11.279
to the nucleus for long term expression. So we can
1671
01:39:11.359 --> 01:39:14.279
take something that used to get you sick and turn
1672
01:39:14.359 --> 01:39:19.840
it into something that delivers healthy genes that are required
1673
01:39:20.000 --> 01:39:24.840
for sustained gene expression of youthful bodies. And basically we
1674
01:39:25.000 --> 01:39:29.479
call that a regain of function and a restoration to
1675
01:39:30.520 --> 01:39:34.640
healthy and therapeutic benefit of these genes. So what you'll
1676
01:39:34.680 --> 01:39:38.720
see is it delivers that gene sequence into the nucleus
1677
01:39:38.760 --> 01:39:41.720
of the cell and then it's transcribed and it creates
1678
01:39:41.760 --> 01:39:45.680
a protein. And those proteins are what make you up.
1679
01:39:45.880 --> 01:39:50.039
So those proteins are very important for the health of
1680
01:39:50.159 --> 01:39:57.199
your body. They're given by IV, intramuscular injection, intranasal injection,
1681
01:39:58.119 --> 01:40:03.279
organ delivery directly, and there are some gene therapies that
1682
01:40:03.319 --> 01:40:06.359
are given topical for children with rare skin disorders.
1683
01:40:06.479 --> 01:40:09.399
We don't do topical gene therapy at this point, but
1684
01:40:09.520 --> 01:40:12.000
we do every other type of delivery.
1685
01:40:13.840 --> 01:40:18.720
Actually, this is an image that was just pulled because
1686
01:40:18.760 --> 01:40:20.920
it was a beautiful image, but actually that's a lot
1687
01:40:21.000 --> 01:40:24.279
what gene therapy looks like. It's a clear liquid I
1688
01:40:24.359 --> 01:40:27.319
think a lot of people wonder what their injection would
1689
01:40:27.319 --> 01:40:30.159
look like, and it is a clear liquid and not
1690
01:40:30.479 --> 01:40:31.560
very scary.
1691
01:40:31.760 --> 01:40:33.159
But very wonderful.
1692
01:40:35.039 --> 01:40:37.920
Now Here is where we're going to show the benefit
1693
01:40:38.000 --> 01:40:41.760
of gene therapy. That's already happening. So on the left side,
1694
01:40:41.840 --> 01:40:45.920
this boy has muscular dystrophy and he's trying to climb stairs.
1695
01:40:46.960 --> 01:40:50.079
And the first place that full of.
1696
01:40:50.119 --> 01:40:52.760
Statin, the gene full of statin that's now often used
1697
01:40:52.800 --> 01:40:56.560
in medical tourism for an aging population was used was
1698
01:40:56.600 --> 01:40:59.800
Induchines and Becker's muscular dystrophy. And this was one of
1699
01:40:59.800 --> 01:41:03.680
the patients. This was him three months after gene therapy.
1700
01:41:05.279 --> 01:41:09.279
Now we're hypothesizing that patients over the age of seventy
1701
01:41:09.439 --> 01:41:12.520
will also need a secondary gene therapy that we're going
1702
01:41:12.600 --> 01:41:15.880
to start using with fullostatin to increase their muscle mass
1703
01:41:15.960 --> 01:41:20.760
and strength due to other delterious effects of biological aging.
1704
01:41:20.840 --> 01:41:22.760
And so you're going to hear about that soon.
1705
01:41:23.199 --> 01:41:27.000
But already we have showed a myriad of successes in
1706
01:41:27.199 --> 01:41:34.159
patients with this gene. Again, according to studies and Chemophilia B,
1707
01:41:35.039 --> 01:41:39.239
with this delivery method, patients thirteen years later are still
1708
01:41:40.520 --> 01:41:45.399
showing expression of gene function, So that's fantastic. So, first
1709
01:41:45.479 --> 01:41:49.800
of all, the area of gene therapy started in fixing
1710
01:41:49.960 --> 01:41:53.399
underlying genetic problems, and this is where it really went
1711
01:41:53.560 --> 01:41:57.960
to show its major successes and what made us realize
1712
01:41:58.000 --> 01:42:03.720
that it had the propensity to problem treat diseases that
1713
01:42:03.960 --> 01:42:09.159
are more complex in order. And these are the therapies
1714
01:42:09.239 --> 01:42:12.680
that are already approved in the gene therapy space.
1715
01:42:12.840 --> 01:42:16.000
So if you think that this is up and coming technology,
1716
01:42:16.039 --> 01:42:16.439
it is not.
1717
01:42:16.720 --> 01:42:21.720
It's already approved by the FDA for thirteen therapies. So
1718
01:42:22.600 --> 01:42:27.039
these are all the therapies that are available now. They
1719
01:42:27.119 --> 01:42:30.239
come with an enormous price take because when you treat
1720
01:42:30.279 --> 01:42:34.680
a small population, you create a very expensive technology. But
1721
01:42:34.800 --> 01:42:39.359
by treating biological aging, we could actually make making these
1722
01:42:39.479 --> 01:42:43.680
type of therapies just free for young patients and patients
1723
01:42:43.680 --> 01:42:45.680
who just need to come up to the line of
1724
01:42:45.760 --> 01:42:54.800
stability with the rest of the population. Preventative medicine is
1725
01:42:54.880 --> 01:42:58.439
probably the best place for gene therapy in those conditions
1726
01:42:58.479 --> 01:43:01.239
that I just showed you. You could consider the gene
1727
01:43:01.319 --> 01:43:04.680
therapy itself a preventative medicine that keeps those children from
1728
01:43:04.760 --> 01:43:09.800
having the outcome of those diseases. If we catch patients earlier,
1729
01:43:09.920 --> 01:43:12.960
we will probably have much more benefit with gene therapy,
1730
01:43:13.319 --> 01:43:18.279
and so I believe that as this technology is shown safe, it.
1731
01:43:18.359 --> 01:43:22.600
Will be used with younger and younger patients.
1732
01:43:24.319 --> 01:43:27.119
On the longevity side, what we can do today is
1733
01:43:27.239 --> 01:43:30.600
we can lengthen your tilomeres. We have so many patients
1734
01:43:30.760 --> 01:43:33.119
data now that shows that we can do that, and
1735
01:43:33.279 --> 01:43:37.000
that's wonderful, and that includes the shortest tilomeres, which are
1736
01:43:37.199 --> 01:43:38.399
very important to target.
1737
01:43:39.000 --> 01:43:41.319
We can increase muscle masks. Definitely.
1738
01:43:41.399 --> 01:43:44.119
I did not work out today, so I'm probably not
1739
01:43:44.239 --> 01:43:48.239
all pumped up, but that is something we can do,
1740
01:43:48.800 --> 01:43:53.239
and that is a beautiful consequence of follostatin gene therapy.
1741
01:43:53.960 --> 01:43:57.239
Now in aging patients who are over a certain.
1742
01:43:57.039 --> 01:43:59.840
Age who don't have precursor stem cells, we are still
1743
01:44:00.000 --> 01:44:04.439
waiting to see how well we can do cognitive enhancement.
1744
01:44:04.720 --> 01:44:09.760
We can accomplish this. I don't want to make any claims.
1745
01:44:09.319 --> 01:44:13.279
Here, but when we do alpha CLOTHO gene therapy, we
1746
01:44:13.439 --> 01:44:18.159
have seen an average increase in a standard deviation of
1747
01:44:18.880 --> 01:44:23.399
IQ tes on IQ tests and that's pretty powerful because
1748
01:44:23.439 --> 01:44:25.600
that could take people who are really low on the
1749
01:44:25.680 --> 01:44:28.880
spectrum and make them more functioning, and people who are
1750
01:44:28.920 --> 01:44:33.720
really high, well it can make them even more awesome. Okay,
1751
01:44:33.920 --> 01:44:38.640
so we need more of those people. So kidney protection,
1752
01:44:39.479 --> 01:44:43.039
that is something that we can do with two gene therapies.
1753
01:44:42.640 --> 01:44:43.079
That we have.
1754
01:44:44.159 --> 01:44:48.119
Mitochondrial therapy. We have a therapy that is specifically for that.
1755
01:44:49.159 --> 01:44:53.279
We are working into five new candidates that we will
1756
01:44:53.319 --> 01:44:57.159
be launching in actually the next six months and getting
1757
01:44:57.159 --> 01:45:01.640
the first human data on, and they all benefit minochondria
1758
01:45:01.680 --> 01:45:05.039
as well. Cardiovascular protection is something we can do with
1759
01:45:05.159 --> 01:45:08.760
one of our gene therapies, metabolic health. Several of our
1760
01:45:08.800 --> 01:45:13.600
gene therapies target metabolic health. Nerve regeneration is something in
1761
01:45:13.720 --> 01:45:17.439
the process, and there's a wonderful gene that is associated
1762
01:45:17.479 --> 01:45:21.760
with re scaffolding. Also, there is evidence that the OSK
1763
01:45:22.039 --> 01:45:24.239
factors benefit.
1764
01:45:24.319 --> 01:45:25.680
Nerve regeneration as well.
1765
01:45:26.159 --> 01:45:29.359
And then of course epigenetic reprogramming that's been all over
1766
01:45:29.640 --> 01:45:31.960
the news and we have our own proprietary form of
1767
01:45:32.079 --> 01:45:32.359
doing that.
1768
01:45:33.000 --> 01:45:35.840
Okay, all right, it's fun to be home because I
1769
01:45:35.880 --> 01:45:38.199
can kind of play around here. So sorry, I've got
1770
01:45:38.279 --> 01:45:39.239
too much energy for you.
1771
01:45:39.920 --> 01:45:43.079
So in ever changing world, we need to genetically modify
1772
01:45:43.199 --> 01:45:49.479
to basically survive the future, survive a dying of death
1773
01:45:49.560 --> 01:45:55.199
and disease, and Jose is definitely behind the crusade to
1774
01:45:55.279 --> 01:45:59.199
make sure that you are aware of our enemies.
1775
01:46:00.079 --> 01:46:04.680
Environment is also an enemy. Living in extreme conditions is
1776
01:46:04.800 --> 01:46:09.800
also an enemy, and so we need to work towards that.
1777
01:46:10.319 --> 01:46:14.199
Enhancing and continual repair is critical for us to get
1778
01:46:14.199 --> 01:46:18.600
the most out of life. We definitely want to stick
1779
01:46:18.720 --> 01:46:21.039
with being able to get out and do the things
1780
01:46:21.079 --> 01:46:24.960
that we love. And I am a huge proponent of
1781
01:46:25.079 --> 01:46:30.640
gene therapy for that integrating technology. Sam Altman was talking
1782
01:46:30.720 --> 01:46:34.520
about how they're looking for genes now to basically help
1783
01:46:34.680 --> 01:46:39.520
integrate technology into you, making it so you don't have
1784
01:46:39.680 --> 01:46:43.840
to maybe lose your devices. Your devices might become part
1785
01:46:43.880 --> 01:46:48.439
of your body. This is fantastic and exciting. And then
1786
01:46:48.520 --> 01:46:52.920
of course exploration of different environments. We know that going
1787
01:46:52.960 --> 01:46:57.159
to space causes accelerated aging. We know that the detriments
1788
01:46:57.720 --> 01:47:01.279
of deep atmospheres also caused damage to our body, and
1789
01:47:01.479 --> 01:47:04.520
so we want to make sure that we're on top
1790
01:47:04.720 --> 01:47:07.399
of that and that we don't limit where we can
1791
01:47:07.479 --> 01:47:12.560
go and who we can go with. So now I'm
1792
01:47:12.640 --> 01:47:15.720
going to talk about some human data, and all of
1793
01:47:15.800 --> 01:47:18.199
this will be my data, because right now I don't
1794
01:47:18.279 --> 01:47:21.760
have permission from patients to release their data. But I
1795
01:47:21.840 --> 01:47:23.920
want to show you what we can do now and
1796
01:47:24.079 --> 01:47:26.720
what we have seen, not just in my body, but
1797
01:47:26.960 --> 01:47:30.119
in other people's bodies as well. So years ago we
1798
01:47:30.279 --> 01:47:34.479
released a paper on my data. We showed that since
1799
01:47:34.520 --> 01:47:37.720
my first gene therapy and my second gene therapy which
1800
01:47:37.760 --> 01:47:39.960
gave me a little bit of a boost of telomeri's
1801
01:47:40.000 --> 01:47:44.079
reverse transcript case. This is a gene therapy that lengthens
1802
01:47:44.119 --> 01:47:48.680
the caps at the ends of the chromosomes. These shortening
1803
01:47:48.920 --> 01:47:52.399
of these caps are associated with a myriad of disease.
1804
01:47:52.960 --> 01:47:54.720
As a matter of fact, all the diseases of.
1805
01:47:54.760 --> 01:48:01.279
Aging and critically short telomeres lead to increase risk of
1806
01:48:01.399 --> 01:48:07.159
genomics instability, which causes cancer. There are a lot of
1807
01:48:07.359 --> 01:48:09.880
different things that I can tell you, but this would
1808
01:48:09.920 --> 01:48:12.880
be a talk all on its own. Since my gene
1809
01:48:12.920 --> 01:48:17.359
therapy is in twenty twenty five, my tilomere length has
1810
01:48:18.319 --> 01:48:21.159
lengthened by an average of five point three years for
1811
01:48:21.319 --> 01:48:25.279
every year I've lived, and my tilimeres are longer since
1812
01:48:25.359 --> 01:48:28.920
these results, and I need to get this year's tilomere
1813
01:48:29.000 --> 01:48:32.479
test done so then we'll have twenty four and twenty
1814
01:48:32.560 --> 01:48:35.439
five and then a release more information.
1815
01:48:35.880 --> 01:48:41.039
Very important short tilomeres in your immune system, which are
1816
01:48:41.079 --> 01:48:42.800
the tilomeres that we actually test.
1817
01:48:43.640 --> 01:48:50.119
Short tilomeres were associated with deaths in COVID nineteen. Number
1818
01:48:50.159 --> 01:48:52.439
one association was immune senescence.
1819
01:48:52.960 --> 01:48:55.840
Whether you're young or you're old, you need.
1820
01:48:55.800 --> 01:48:59.279
To have cellular division in the immune cells or they
1821
01:48:59.399 --> 01:49:04.960
cannot divide to attack an infection. So it goes beyond
1822
01:49:05.239 --> 01:49:11.600
just chromosomal stability and living longer in certain benefits of that. Also,
1823
01:49:12.239 --> 01:49:17.760
things like lobsters and certain clams, they may be living
1824
01:49:17.840 --> 01:49:20.840
as long as they do, which is in extremely long
1825
01:49:20.920 --> 01:49:24.399
time hundreds of years due to having to lameris turned
1826
01:49:24.479 --> 01:49:26.960
on in every cell. So I am a proponent of this.
1827
01:49:28.039 --> 01:49:30.720
We have not seen drawbacks or adverse drug events, and
1828
01:49:30.800 --> 01:49:32.920
we've watched patients for over five years.
1829
01:49:35.359 --> 01:49:36.119
Full of satin.
1830
01:49:36.520 --> 01:49:39.439
We can increase our muscle mass as long as you
1831
01:49:39.520 --> 01:49:42.319
have precursor stem cells, and we'll be able to increase
1832
01:49:42.359 --> 01:49:44.920
your strength even if you don't. And we'll talk about
1833
01:49:44.920 --> 01:49:47.399
a company that is going to help replace those stem cells.
1834
01:49:47.439 --> 01:49:51.560
Anyway, this is my results that were put out.
1835
01:49:51.880 --> 01:49:57.000
This is my MRI image and my muscle mass increased,
1836
01:49:57.119 --> 01:50:01.359
and my intramuscular fat went down. Full of statin comes
1837
01:50:01.399 --> 01:50:03.119
with a bunch of benefits. If you look at the
1838
01:50:03.199 --> 01:50:07.760
literature review around it, it's kind of crazy. It helps
1839
01:50:07.800 --> 01:50:12.239
with tissue repair, regeneration, It turns down inflammatory markers. We
1840
01:50:12.359 --> 01:50:15.880
believe that re establishing the immune system is dependent on
1841
01:50:16.039 --> 01:50:19.600
turning down these markers. That the things that we used
1842
01:50:19.640 --> 01:50:22.880
to think actually major immune system really strong, which was
1843
01:50:23.039 --> 01:50:27.760
stressors and inflammation, actually keep it from rebuilding your body.
1844
01:50:28.479 --> 01:50:30.000
And I'm working with a.
1845
01:50:30.039 --> 01:50:32.520
New company that's going to be showing that in human
1846
01:50:32.640 --> 01:50:34.279
data over the coming year and a.
1847
01:50:34.279 --> 01:50:37.319
Half, So this is really important.
1848
01:50:37.760 --> 01:50:41.000
It may actually even have a protective role that's full
1849
01:50:41.039 --> 01:50:44.279
of statin in prostate and breast cancer, and that's something
1850
01:50:44.359 --> 01:50:47.600
that we're going to want to watch and see. And
1851
01:50:47.720 --> 01:50:53.119
of course, increase muscle mass is associated with insulin sensitivity,
1852
01:50:53.279 --> 01:50:57.760
which is vital to not have type two diabetes. Again,
1853
01:50:58.000 --> 01:51:01.119
we will have growing evidence there. When we talk about
1854
01:51:01.199 --> 01:51:04.680
brain health, we often talk about alpha CLOTHO and one
1855
01:51:04.720 --> 01:51:07.560
of the things that my company wanted to do starting
1856
01:51:08.000 --> 01:51:13.000
in maybe two thousand and sixteen or seventeen after I
1857
01:51:13.119 --> 01:51:16.920
was treated, is learn how to redose aav We're the
1858
01:51:17.079 --> 01:51:20.439
only company in the world that can do it that
1859
01:51:20.600 --> 01:51:23.439
we know of, and we wanted to prove that we
1860
01:51:23.560 --> 01:51:27.840
were having a therapeutic effect even with redosing events. So
1861
01:51:28.880 --> 01:51:32.119
on the left side you see my alpha CLOTHO levels.
1862
01:51:32.199 --> 01:51:36.119
This was after I had already been treated in twenty twenty.
1863
01:51:37.000 --> 01:51:39.960
But what it shows is that I'm in the ninetieth
1864
01:51:40.079 --> 01:51:44.319
percental for alpha CLOTHO for my age, and that's fantastic.
1865
01:51:44.439 --> 01:51:47.199
That means the first gene therapy probably worked.
1866
01:51:48.880 --> 01:51:52.840
Then we did a redosing protocol and on the right
1867
01:51:53.000 --> 01:51:56.399
side that is an increase to the ninety fifth percental
1868
01:51:56.560 --> 01:51:57.439
for alpha clotho.
1869
01:51:57.960 --> 01:52:00.760
And since then, I think my school or because we.
1870
01:52:00.800 --> 01:52:06.279
Did it again, I just keep doing it and now
1871
01:52:06.359 --> 01:52:09.920
it's one thy three hundred and I think twenty eight.
1872
01:52:10.159 --> 01:52:14.159
So now I'm basically hovering in the top area.
1873
01:52:14.600 --> 01:52:17.039
I don't really want to go over that where we
1874
01:52:17.159 --> 01:52:19.920
want to get the alpha clotho in the maximum area.
1875
01:52:20.279 --> 01:52:23.279
We don't want to take it over what would be
1876
01:52:23.720 --> 01:52:27.680
natural for a human homeostasis at this point, so I
1877
01:52:27.880 --> 01:52:30.520
will be working on some other.
1878
01:52:30.479 --> 01:52:31.960
Data years ago.
1879
01:52:32.319 --> 01:52:36.000
Let's see, this was in twenty twenty one we launched
1880
01:52:36.000 --> 01:52:38.880
a paper of a safety study with h turt and
1881
01:52:38.960 --> 01:52:43.520
alpha CLOTHO and patients with dementia and we saw a benefit.
1882
01:52:43.840 --> 01:52:46.840
And I actually took this to the US FDA and
1883
01:52:46.960 --> 01:52:49.319
did a pre I ind on it, and they asked
1884
01:52:49.399 --> 01:52:52.479
for eight million dollars worth of animal studies even though
1885
01:52:52.520 --> 01:52:55.520
we had human data. So that was at the point
1886
01:52:55.600 --> 01:52:58.399
that we tipped, and we started licensing out to other
1887
01:52:58.560 --> 01:53:01.399
companies who could use it in the locations they were in,
1888
01:53:02.199 --> 01:53:05.479
or could they had the aptitude and the fortitude to
1889
01:53:05.640 --> 01:53:08.560
raise the money to get into the US FDA. And
1890
01:53:08.800 --> 01:53:10.880
I'm happy to tell you we've got new two new
1891
01:53:10.960 --> 01:53:14.319
groups coming on to use this therapy and patients with dementia,
1892
01:53:14.359 --> 01:53:16.000
one in the US and one in the Bahamas.
1893
01:53:16.000 --> 01:53:19.000
But we'll talk about some more coming up here. But
1894
01:53:19.159 --> 01:53:19.880
what happened.
1895
01:53:20.720 --> 01:53:24.479
Cognitive scores went up and biological age went down.
1896
01:53:25.039 --> 01:53:28.560
It was not a cure, but it did offer.
1897
01:53:28.399 --> 01:53:31.640
Hope for some of these patients, and one patient went
1898
01:53:31.720 --> 01:53:34.720
from living in assisted living to living on their own.
1899
01:53:36.039 --> 01:53:38.680
We really want to work this towards a medical cure.
1900
01:53:39.239 --> 01:53:42.600
These were incredibly low doses. We're hoping with higher doses
1901
01:53:42.800 --> 01:53:46.479
and the insertion of a third gene that we want
1902
01:53:46.560 --> 01:53:51.720
to use, we're going to get better results. So what
1903
01:53:52.079 --> 01:53:56.199
happens if we keep curing mice, but we can't get
1904
01:53:56.239 --> 01:53:59.359
things to humans. As you know, all of you probably
1905
01:53:59.479 --> 01:54:03.279
know not get into this industry to do research and development.
1906
01:54:03.439 --> 01:54:06.199
I got into this industry to help patients, and that's
1907
01:54:06.239 --> 01:54:07.600
why scientific.
1908
01:54:07.239 --> 01:54:11.119
Accuracy is so important for me. We're a different beast.
1909
01:54:11.760 --> 01:54:14.199
We believe that if you've got good medicine, you'd be
1910
01:54:14.359 --> 01:54:17.800
using it, and if you're not, we're going to put
1911
01:54:17.840 --> 01:54:19.720
you to the challenge of getting it up there.
1912
01:54:20.560 --> 01:54:23.680
I've spent about a third of my time in regulations.
1913
01:54:24.000 --> 01:54:27.960
I worked in a myriad of zones, one zone that
1914
01:54:28.880 --> 01:54:32.960
actually approved their regulations last year to use gene and
1915
01:54:33.039 --> 01:54:36.640
cell therapy, and I will continue to push for new
1916
01:54:36.880 --> 01:54:40.039
innovative areas to open up for the use and access
1917
01:54:40.079 --> 01:54:44.840
of these technologies, including the United States. We work with
1918
01:54:45.439 --> 01:54:50.840
several concierge medicine companies, and these are healthcare companies that
1919
01:54:51.119 --> 01:54:54.720
basically you're given a special person who handles your dossier
1920
01:54:55.279 --> 01:54:58.800
and they help you get access to technology.
1921
01:54:58.359 --> 01:55:00.479
All over the world. This is a Swiss group.
1922
01:55:00.640 --> 01:55:04.239
They have clinics in Switzerland and we also work with
1923
01:55:04.399 --> 01:55:07.399
clinics all over the world with gene and cell technology
1924
01:55:08.239 --> 01:55:13.079
and almost anything that is very high value that would
1925
01:55:13.119 --> 01:55:16.399
be hard to get through a normal system. We also
1926
01:55:16.560 --> 01:55:20.039
have these four licensing partners on top of a couple
1927
01:55:20.199 --> 01:55:23.439
other ones. We've just added. Future Health is in China.
1928
01:55:24.159 --> 01:55:26.840
They're a fantastic group. They're starting to work with a
1929
01:55:26.920 --> 01:55:30.640
Chinese government in ninety two hospitals to move technologies forward.
1930
01:55:31.439 --> 01:55:34.600
On the upper right side is an Unlimited Bio. They've
1931
01:55:34.600 --> 01:55:39.960
been working in Honduras and they treated a Kardashian. Hey,
1932
01:55:40.159 --> 01:55:43.239
that is really cool. They're a cool group, very cool group.
1933
01:55:44.279 --> 01:55:47.119
On the bottom left is Integrative Health Systems. They have
1934
01:55:47.239 --> 01:55:51.039
treated over three hundred patients without an adverse drug event
1935
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and knock onward. We're very proud of them and they're
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an incredible group of thirteen medical doctors and a concierge
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system that helps with all the pre impost and all
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the travel arrangements.
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And on the bottom right is a group I was
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going to talk about. That's re gen Cell.
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They're working on replacing your stem cells, but not just
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replacing your stem cells, reprogramming them and adding genetic function
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01:56:17.000 --> 01:56:19.760
to them. And so you're going to hear more about
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them over the next couple of years. And that is
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a super benefit because for people over the age of
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sixty five, they're down to five percent of their stem cells.
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And without these stem cells, you cannot regenerate your body.
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So these are very very important cells to the body.
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So they need to be replaced. And if they're reprogrammed first,
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that's a benefit. And if they have better gene function,
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even cooler. So I know that we move quickly, but
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we are an engine for change. We are humanitarian group
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of scientists, medical doctors and business people who believe that
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we need to spend our time for the betterment of humankind.
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And so I want to leave you with this quote.
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He who rejects change is the architect of decay. The
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only human institution which rejects progress is the cemetery. I
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suggest you don't land there. Thank you so much, thank you,
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thank you very much.
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Liz.
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We we love you, but we have to say goodbye,
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good bye, goodbye, thank you, thank you, bye bye.
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Greetings and welcome to the United States Transhumanist Party Virtual
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Enlightenment Salon. My name is Jannati Stolier of the Second
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and I am the Chairman of the US Transhumanist Party.
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Here we hold conversations with some of the world's leading
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thinkers in longevity, science, technology, philosophy, and politics. Like the
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philosophers of the Age of Enlightenment, we aim to connect
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every field of human endeavor and arrive at new insights
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to achieve longer lives, greater rationality, and the progress of
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our civilization.
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Aging is a natural process, but it's a process which
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both our health and wealthy.
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We are lucky to have longevity researchers developing rejuvenation therapies.
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Welcome to Transvision twenty twenty five.
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Now let's move into a real investor.
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A real investor.
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You know, I have known Angel Versetti and what he
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has been doing with his family office and also Dodge
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dot org. And he has a lot of things to
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say about how big this industry is, what will happen
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in terms of investment possibilities, venture capital, and where we
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are going to go with the longevity industry.
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So let's welcome Angel.
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Thank you everyone, it's a pleasure to be here in
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the beautiful city of Madrid. So my presentation is titled
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some Candidate Raw thoughts on the state of longevity as
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an investment. So it's thoughts a lot of them and
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through the prism of our experience as an investor and
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their candidate, meaning that we want to be bullish, but
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then there are some challenges we need to acknowledge.
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So I decided to use the quote here.
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From a Spanish writer and philosopher, Miguel de Unamuno. I
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hope I'm pronouncing it correctly. That explains my style, which
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is minimalistic. I think post child GPT raight. Far too
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many fanciful designs out there, so I try to focus
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on the content and briefly about my journey. I'm a
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serial entrepreneur, having exited four different companies, two of them
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became unicorns in Web three and II domains. I also
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owned dosh dot org, which became the first online community
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for doshcoin, which became one of the most famous cryptocurrencies
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in the world.
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So I host the forum where the.
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First pictures of the dog were shared, and that would
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have been a joke, but that joke turned out to
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be nearly one hundred billion dollar market cap thing. So
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there was a nice joke, and as of this year,
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we've decided to focus entirely on longevity in terms of
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our new ventures. Although I have been in the community
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in various forms as an investor, grant making organization, and
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an entrepreneur for about five and a half years since
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the early days of COVID. So just a few clarifications,
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it's difficult for us to define what exactly we are
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because we're not really a VC. Here, you have some
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you know, what's scratched is what a typical VC is like,
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and what's written is what we have. So a venture
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capital fund will typically have money from limited partners as
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people who give money to the VC to invest. Therefore,
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their mandate tends to be fixed because when you promise
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someone to invest their money in a certain way, you
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kind of have to stick to your promise. A lot
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of VC funds have a particular timeline through which they
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have to return their money to the investors. That makes
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a lot of them sure to meetium term, and that
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is not a problem in many industries like software, but
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that is a problem for the space like longevity, which
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requires much longer timeframes of investment a lot of the
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funds that I have met.
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It's my opinion.
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I'm sure they will disagree, but I felt that they
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spray and pray, meaning that they invest in a bit
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of everything, but they don't have a particular like conviction bets,
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and they tend to source a lot of deals externally.
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In our case, the capital is our own, therefore the
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mandate is flexible.
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We can afford to be long term and we are.
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Happy to support radical moonshots that move the needle. And
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we also have the venture builder approach of which I
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will talk about later. So we're also not a typical
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family office, because family offices tend to be conservative and defensive.
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Their goal is to preserve their wealth rather than grow it.
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As a result, they tend to be diversified and passive allocators.
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In our case, we're entrepreneurial. We're happy to take risks,
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sometimes not too happy and when the results are not
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that great, but that's what we're in for. I guess
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we are focused on wealth growth for ourselves and for
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the industry generally. Therefore, we make concentrated bets, whereby we
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have a lot of skin game and we push the
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companies to really focus on being operationally viable and commercially viable,
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and we are a hands on operator, meaning that we
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like to be very actively involved with our investments. I
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would say around ninety to ninety five percent of family
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offices do not operate this way. Therefore, I'm not even
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sure if the name family office is correct for us.
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And when I started just researching longevity, I read a
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bunch of books by some of the most famous people
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in longevity, and if I were to summarize them in
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five small bullet points, most of them just said eat well, exercise,
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good sleep, no stress.
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No bad habits.
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And while I'm like, Okay, why do I need all
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these Harvard PhDs and Stanford professors and whatnot to really
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tell me what I knew since I was a kid,
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what my parents told me to do. Moreover, when I
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researched a be deeper into the history of longevity, there
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was an ancient Chinese philosopher and physician Gihong who said,
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even if one performs breathing exercises and strength training as
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well as in herbal medicines, this can only extend the
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years of your lifespan, but it will not save you
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from death, So that guy knew about it two thousand
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years ago, and we're still like just repeating the same stuff,
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and we're still struggling in the same way. Although of
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course my personal response to that is that thankfully today
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we have so many technological advancements so that hopefully we
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can move beyond pure wishful thinking. So general, my thesis
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is that longevity is hard. There are a number of
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reasons that we've identified through our research. Again, these are
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mostly opinions. I mean, there are many kind of anecdotal
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stories or specific backing them, but these are mostly my thoughts,
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so don't take them as facts. But it feels that
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their market is still immature and fragmented. People are still
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fighting about like what the definition of longevity should be.
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I know it was a big subject of discussion at
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this year's ARDD in Copenhagen. And therefore, if you don't
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have even the universally accepted definition, of course, is difficult
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for regulatory frameworks and standards to be developed, so they're
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either poorly developed or non existent. They feel this multi
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dimensional and highly complex, and I would say there are
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two big chunks of participants when I look at it
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from the business perspective. On the one side, there are
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I call them hypocrite hygh writers. These are businesses that
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don't really care about longevity, but they use the word
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because it's an attractive investment term. And on the other side,
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I mean, I call them like fanatic dreamers. They religiously
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believe in longevity, they believe in the necessary to radically
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increase lifespan and so on.
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But they are just like they're focused.
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On it like a religion, and you need to find
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some golden means, some middle ground, and then of course,
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I mean it's a no brainer. But biology itself is hard,
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and I say that as a non biology guy coming
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from a different background, and of course that's you know,
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there are many examples where it's not just easy to
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predict what's going to happen. So longevity startups are also hard.
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So when we extrapolate from that to startups in particular, that's.
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What we're focused on.
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So a lot of them have again that's you know,
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what our assessment is from our scientific and due diligence teams,
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but they frequently lack clinical depth on clinical guidelines diverge
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from country to country, so that's difficult for them to
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be comparable to each other. Of course, a lot of
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them have unsustainable margins and economics. We have observed a
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number of high profile failures where when we try to
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analyze what exactly did the team go wrong when the
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company went bankrupt, there was not like particular reason, It
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was not like an obvious failure or mistake, just the
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economics didn't work. There are cases of longevity clinics that failed,
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There are cases of companies that are biotech that failed,
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and a number of others. So the graveyard of startups
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in longevity is huge. A lot of startups engage in
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misleading marketing, which leads to low consumer trust when they
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make some huge statements and the over promise that leads
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to the negative perception of the industry by the media
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and by some of the consumers. It's oftentimes hard to
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measure impact and outcomes, especially when you deal with human lifespan,
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which you know is obviously multi decade long. So how
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can you meaningfully prove to people that it can work
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amongst a lot of users? There is poor retention and
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follow through, so a lot of people that typically are
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excited to start it out, to try it out, to
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do the procedures or take.
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Whatever supplements or some other you know, more more.
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Advanced interventions, but they typically there's very low follow through,
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so it's almost a cliff when we identified a number
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of startups from their first client or first you know
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intervention to the next one. And then generally within the
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market context sees a lot of longevity companies overlap with biotech.
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There is generally a biotech downturn, so it's at historical
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lows over the past couple of decades, so that leads
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to scarcity of capital. And on the next slide, I'm
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sharing a few quotes from a few people. I tried
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to make it a semi anonymous because some of these
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conversations were just private or chatter and rule, but I
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found it to be interesting. And these conversations are all
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from the past three four weeks, by the way.
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So.
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Both from a CEO of a public company who said
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we had to pretend to be a biotech company for
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our i PO and not talk about longevity or else
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the markets would freak out. Then I talked to a
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fund who also says we promised to our LPs to
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allocate to conservative pharma place and just a little bit
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to longevity because otherwise we struggle to raise money. Another
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startup company said we target disease X rather than aging
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to look more credible to investors. And lastly, a you
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know researchers said, we pretend not to work on radical
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longevity because we don't want we want to continue receiving
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research grants. And they also said, we don't want to
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a random religious fanatic to come and shoot us. So
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these are all real like quotes from pretty serious companies,
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people or funds I've met. So it's a lot about perception,
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how the investors perceive it, so we need to change
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the narrative and the perception amongst the investors. And then
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the last bit also of course, talks about personal safety
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of some people who are working on more radical aspects
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of longevity. And I met quite a few people who
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prefer to stay in stealth, for example, because they are saying,
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I'm not sure you know if somebody might come and
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try and shoot us. So these are definitely So the
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previous conversation about the necessary necessity of lobbying definitely is
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important than just generally engaging media, the public opinion and
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so on is equally important. So yeah, when I was
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interviewed after ARDD like, so what's your conclusion from a
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R I said, well, I guess we're all going to die.
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So there is a lot of you know, like, there
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is a lot of course progress. But then at the
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same time, as at LBF whom someone mentioned today, the
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Longevity Biotech Fellowship in which I participated, their you know,
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their main argument is that as of today, there are
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zero credible, credibly verifiable like longevity interventions on the market,
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and it's important to be aware of that that this
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is you know, we still have a lot of things
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to go. But you know, I was asked to be
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optimistic for this presentation.
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Therefore, let me.
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Say why I am here and not just like giving
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up and left. I think the market opportunity for longevity
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is definitely there. I was asked to prepare like estimates
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of the market size and so on.
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I didn't want to give random numbers. I'm not a
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fan of that.
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So I couldn't find any credible estimates of the market.
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And not least because well, when you have no definition
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for what kind of market you're talking about, it's hard
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to find an estimate. So I have seen various attempts
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to extrapolate to biotech space or set up peutics.
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Or farm or healthcare.
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I definitely am not the best person to judge which
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of those is suitable.
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But importantly there are here on champions.
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Like from the previous quote I showed you the company
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that is a public, publicly tradable company that has to
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pretend to be just we're a normal biotech or we're
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a normal pharma company. They are actually the head on
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champions of longevity. And hopefully when it becomes more acceptable
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for the public and investors to support the notion of
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increasing lifespan and health span, they can be more open
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about it and that can create a snowball effect. Secondly, well,
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I think there's just generally speaking, an infinite market size
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because who does not want to be healthier?
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Like if lifespan.
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Extension is maybe there are more people who could argue
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about that. I don't think there's barely anyone in the
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world who would not want to be healthier generally, so
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the health span part of it is a no brainer.
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The whole planet is your market when it comes to
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like living longer and so on. Again, I'm a historian
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by background, actually, so I just observe that like from
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the historical perspect from the times of pharaohs of ancient
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Egypt and the ancient kings and the emperors to the
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wealthy leads of today, a lot of them always sought immortality,
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They sought extension.
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Model of lifespan and so.
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On is deeply embedded into almost all religions, philosophies or folklore.
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The first written kind of like story, the book the
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novel Gilgamesh, you know that we have in the current
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like scnsidicly, the first book written that has stayed until
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the modern times. It deals with questions of seeking, you know, immortality.
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So therefore that leads to a lot of I want
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to believe investors, the optimist investors. Some of them come
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from fields such as crypto or AI, and there have
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been discussions that there are dreamers in a way, but
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it's important to have investors who are dreamers, who are
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not just like conservative, careful people looking for basic things.
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And I also think that a acceleration definitely brings hope
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for a lot of longevity challenges. So when people said
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these trials can take long, we're you know, simulating a
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certain kind of research can take longer, and so on.
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There is some degree of hope there, although I have
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also met a lot of people say so many things
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in biology can't really be meaningfully you know, accelerated using AI.
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And generally I'm also you know, generally looking at cycles
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in the markets. So when something is at the bottom,
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and biotech is set by everyone to be at the bottom,
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then that tends to rise.
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And investors are always.
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Looking for a good bubble, like it's just like people
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always want something that the narrative is there, and then
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they creates a snowball effect. And we are currently in
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the AI bubble obviously, but maybe the next one will
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be a longevity bubble. So briefly about our approach, so
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we tuck all this so since I mentioned that we're
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neither a VC fund nor a proper family office, so
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we take the approach of a longevity venture builder. So
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our goal is to find this promising very early stage
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startups or pre startups that try and move the needle
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on lifespan or health spun. We want them to be
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R and D and science or even not marketing things.
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So it's you know, there are plenty of others who
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can support marketing place, but we look for the evidence
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back to scientific projects and that are grounded in commercial reality,
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and therefore we're looking for such collaborations. We're actively exploring
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them now with universities and with entrepreneurship groups. As mentioned,
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we are an investorpreneur, so we are both investors and entrepreneurs.
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We try and be the founding partner and help startups
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to really focus on their operations, scaling and business growth.
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That's something that most vcs that I talk with, given
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that they have forty fifty companies in their portfolio, you
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can't meaningfully grow forty fifty companies in parallel. Even doing
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four or five companies in parallel is extremely hard. And
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therefore we want to focus on like a small group
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of superheroes. And yeah, we commet our own capital, and
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then I am working with a number of other family
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offices where I know that the principles or the family
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members themselves have a personal interest in this space. I
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like to remind the projects I work with about what
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investment actually means. A lot of them tend to just assume, Okay,
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doing longevity is good for humanity, and therefore you owe
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me money. I think that's the wrong approach, and I
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always try and like say either you know, you should
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say you're a research organization and that's fine, but if
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you're a startup, you should have a commercial model. You
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should be able to explain to your investors are going
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to bring money to them. I know it sounds like
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why is this guy explaining this? But like so many
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companies I meet, somehow just totally ignore that. And Yeah,
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the questions that we ponder upon very often. So what
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niches of longevit are worth investing in, how to do
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risk or discard a project with minimum losses? How to
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achieve both impact and profitability. It's important because we want
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to do both. Ideally, how to predict the future behavior
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of founders, that's a general startup question, not only for longevity.
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And then how to navigate the whole geopolitics and focus
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on progress and in today's world, unfortunately politics are messy,
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a lot of popularism and at least to lack of
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scientific collaboration oftentimes on top of a lot of stigmas
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that longevity itself still has today. So that is something
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we ponder upon, so that instead of you know, saying
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it's not possible to reach the stuffs and forever, we
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will add a yet that we can make it happen.
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Thank you.
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Wow, Angel, that was a powerful presentation, really fantastic. You
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covered most of everything we wanted to have in this session.
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We are very excited to have this panel to talk
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about public advocacy and what different people are doing in
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terms of advocacy. And each one will introduce themselves better
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than I can introduce them, So it is I think
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much much better to hear from them what they're working on.
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We just had a little session to know what they
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are working on, and then we will have some questions
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and debate a little bit in the panel. Okay, so
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let's begin now that we have everybody uh sitting in
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their place, and each one has a different perspective on
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what they are doing and public advocacy for longevity, but
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they are all committed to longevity and biological rejuvenation. So
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let's begin with Carmen Simon. Matteo, you have a microphone.
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You need to turn in green. Now is red. Once
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it is green, you can talk.
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Please, Thank you. An applauch to Carmen.
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So good good afternoon to everyone.
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First, I'm going to introduce myself, So I'm Carmen Simon.
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I'm a scientist.
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I work in the National Center for Biotechnology, which belongs
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to the highest public research institution.
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In Spain, which is called.
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Spanish National Research Council, and I do research. I'm a virologist.
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I work in plan virus. But I'm here because, as
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to have seen before, I found more than ten years
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ago I founded an association which is called a paternal Latentsia.
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Only with the name you already know something about it.
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And we put.
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That name A Patrina latentia because we do care about
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science and we do care about the investment in science.
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So a Vadrina Latentia is a.
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Place that has different parts of interest and along the
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journey maybe I can explain to you later what do
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we do. But the main idea is that we want
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society and also the government's understand that investment in science
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is very very important because finally all the results we
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got with our research, with our investigation finally impact in society.
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Of course, here in this meeting about longevity, so only
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we can increase in longevity and also the well being
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of people by doing research, So the investment has to
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be there, but also we want to really diffuse in
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the society the results we got in our investigations. And
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also not less important is that we are very worried
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because our kids and or young people don't want to
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be scientists, and this is really very very.
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Tough to know.
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And we want to promote the vocation of these people
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to be interested in doing science.
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So that's more or less the main ideas I.
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Wanted to show with to share with you in the
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beginning of my talk.
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Thank you, thank you very much, Carmen. So now let's
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go in a different perspective and Serchio will give us
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a few ideas of what he's doing to advance longevity.
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Cercio, Okay, yeah, I think it's best that we introduced
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ourselves briefly first and then a little longer because we
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have a lot of time. So my name is Sergio
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Martinez Ralga Taretro. I've been in the community, in the
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longevity community for about twenty years. Twenty two years. I
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met has recording a conference like this in Helsinki in
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two thousand and six, so that's nineteen years ago, and
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I've covered many conferences. I really like documenting these events.
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I think they're historical and worth preserving. And I've got
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involved with the community too to help make the ideas
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rich wider audiences. It's still kind of unfortunate that it's
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not more widespread, like Coovery said in his remarks, and
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my main contribution, I think to the community was founding
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the first plashunist political party in the world, Aljanha Patrista
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Alpha in now twelve years ago, almost to the date.
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It's the seventh of October, that's our anniversary. And exactly
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a year later, the Transformitist Party the US was founded,
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which was just chance, and we've basically brought this movement
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to existence, having a political movement around transhumanism, both the
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Allianta Patrista here in Spain and the Transumitist parties which
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were founded in first in the US and then another
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one in England I believe. I don't know if that's
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still going, but yeah, I will advocate for much more
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public investment on longevity science, obviously, which we also do
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our march to push for. But I will talk a
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little bit more about the party in a few minutes.
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I'll let the.
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Next person, beautiful, thank you. Actually we heard first a biologist,
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second assysicist by training, and now we have Clara tell us,
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how about you.
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My experience is an innovation healthcare. Hello everyone, Clara Claire Fernandez.
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I am the longevity clinic in Valencia that Anhel was
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talking about. Because last week Angel d Lan Aubrey, Natalie Ines,
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a lot of the scientists and biotech longevity biotech community,
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we're in my clinic. I hosted the Longevity Biotech Fellowship.
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My clinic is in Valencia, and I'm going to be
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talking about how the unique ecosystem and the unique model
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that we have built and how what is our perspective
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on how to democratize the access of longevity to society.
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Just as a little bit of an introduction, we are
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quite a bit clinic. We have an average of six
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hundred patients per day that stay with us for ten days,
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which has enabled us to create a unique model of
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delivering longevity treatments at a very efficient skill. One of
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the key elements that I'm going to also be talking
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about is the importance of collaboration between longevity clinics and
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the clinical scientific community. As most of the bank Guard
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treatments are happening in longevity clinics, we need to make
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sure that those data are analyzed and are translated to science,
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so we can keep supporting what's happening and publish it
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in scientific papers.
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Thank you so much, Clara.
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So let's hear from Carlos that also travels all the
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time and here's doing many things, not just in Spain,
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but all over Latin America.
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Thank you so much for inviting me. Thank you so much,
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because Luis is always a pleasure. Also from that, I'm
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very honored. I'm amazed by a number of people that
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have been here over the last few days. I'm also
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very thankful to my peers in this pandel because I've
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been hearing from them a few minutes ago. I'm very pressed.
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So my name is Carlos Ruta. I've been in this
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sector for thirty nine years. I basically do a couple
459
00:24:47.720 --> 00:24:51.359
of things. I am for profit investor, so I'm invested
460
00:24:51.400 --> 00:24:53.200
in more than eight hundred and fifty.
461
00:24:52.960 --> 00:24:54.720
Projects all over the place.
462
00:24:54.759 --> 00:24:58.599
As you said, this is for profit but not for profit,
463
00:24:58.640 --> 00:25:03.400
which is my most enthusiastic piece of the cake. I'm
464
00:25:03.440 --> 00:25:08.079
also an investor in developing what I have denominated digital
465
00:25:08.119 --> 00:25:12.079
health cities. And you would be guessing or thinking.
466
00:25:11.799 --> 00:25:16.160
What is that about. Well, this is my interpretation.
467
00:25:16.519 --> 00:25:18.759
It is only our interpretation of what we mean by that,
468
00:25:18.839 --> 00:25:21.920
but basically we create spaces. So we have in Madrid.
469
00:25:21.920 --> 00:25:23.680
We launch in Madrid on the fifth of June, the
470
00:25:23.720 --> 00:25:29.400
first digital city worldwide. We have two campuses. Campus one
471
00:25:29.480 --> 00:25:33.359
is Last marthadis eighty thousand scare meters and Campus two
472
00:25:33.440 --> 00:25:36.880
is San Fernando more than one hundred thousand scare meters.
473
00:25:37.200 --> 00:25:38.279
And what do we do there.
474
00:25:38.599 --> 00:25:42.079
Let me first very quickly remind everyone that this is
475
00:25:42.440 --> 00:25:46.720
the only sector in which the consumer, which is called patient,
476
00:25:47.440 --> 00:25:50.240
is not a decision maker. Let's keep this in mind.
477
00:25:50.680 --> 00:25:52.720
So I want to buy an iPhone, I go to
478
00:25:52.759 --> 00:25:55.480
the shop and I buy my iPhone. I'm the decision maker,
479
00:25:55.599 --> 00:25:59.359
I'm the payer, I'm the user. But in this market,
480
00:26:00.079 --> 00:26:02.960
I am the patient. But remember, there is a doctor
481
00:26:03.000 --> 00:26:09.240
who prescribes, there is someone called pharmacist who dispenses, and
482
00:26:09.279 --> 00:26:12.079
then there is someone called insurer or government who pays
483
00:26:12.119 --> 00:26:16.119
for this party, especially when we are talking about prescription.
484
00:26:17.039 --> 00:26:20.279
And then I'm the patient. I'm using these medicine medical men.
485
00:26:20.400 --> 00:26:26.000
So five six, seven stakeholders for one fact. So what
486
00:26:26.079 --> 00:26:28.799
we do in these cities is interesting. First, we put
487
00:26:28.839 --> 00:26:33.559
together public and private. This is vital, this is critical.
488
00:26:34.200 --> 00:26:37.680
This is the neurological bit of everything we do. And
489
00:26:37.799 --> 00:26:41.759
once we put together public and private sectors, we put
490
00:26:41.839 --> 00:26:45.599
together a chemist with a doctor, with an association, with
491
00:26:45.640 --> 00:26:49.759
a foundation, with a laboratory, with a distributor, and we
492
00:26:49.799 --> 00:26:51.599
make things happen in those cities.
493
00:26:51.640 --> 00:26:54.240
So our advocacy, as we.
494
00:26:54.079 --> 00:26:57.160
Were meant to say as part of this panel, is
495
00:26:58.000 --> 00:27:01.000
we am not an expert as my peer in longevity.
496
00:27:01.200 --> 00:27:05.480
I must admit actually I was a very very bad student,
497
00:27:05.680 --> 00:27:06.440
if I recall.
498
00:27:07.359 --> 00:27:09.000
But what we do is different.
499
00:27:09.319 --> 00:27:12.880
We try and do something which is in our view necessary,
500
00:27:14.200 --> 00:27:20.519
which is melting together from the entrepreneurship side of things,
501
00:27:21.359 --> 00:27:24.160
all of these people who are enthusiastic and are part
502
00:27:24.160 --> 00:27:28.519
of this ecosystem into one discussion, so we integrate. I
503
00:27:28.559 --> 00:27:31.400
would say, we are integrators, and that's how I would
504
00:27:31.440 --> 00:27:33.640
put it. And then over the next few minutes we
505
00:27:33.680 --> 00:27:36.440
will be talking more about some of the details.
506
00:27:36.559 --> 00:27:38.480
Thank you, Thanks to you, Carlos.
507
00:27:38.839 --> 00:27:42.119
And now let's hear from Marianna that I have the
508
00:27:42.160 --> 00:27:45.559
pleasure to know her for over ten years since the
509
00:27:45.599 --> 00:27:50.160
beginning of Rather First, which is the biggest global event
510
00:27:50.279 --> 00:27:54.119
on longevity revolution against agent and death.
511
00:27:54.319 --> 00:28:00.960
So Marianna and wow, yeah, thank you for the invitation.
512
00:28:01.200 --> 00:28:03.440
Thank you for having this space, thank you for bringing.
513
00:28:03.200 --> 00:28:04.240
All these people together.
514
00:28:05.640 --> 00:28:08.599
So I will be talking to you about two different
515
00:28:08.680 --> 00:28:12.920
arms to different organizations and not for profit and non profit.
516
00:28:13.359 --> 00:28:15.359
And the first one it's what you just mentioned, which
517
00:28:15.359 --> 00:28:17.400
is what brought us together and how we met and
518
00:28:17.440 --> 00:28:19.160
how I've met a lot of you and a lot
519
00:28:19.200 --> 00:28:22.680
of the people that have spoken this weekend. It's the
520
00:28:22.759 --> 00:28:25.559
Coalition for Radical Ethe Extension. It's been and not for
521
00:28:25.599 --> 00:28:30.000
profit created about eleven years ago, and then its main
522
00:28:30.039 --> 00:28:32.920
mission was to bring together and bridge the gap between
523
00:28:33.000 --> 00:28:37.960
scientists and non scientists. So yesterday doctor memmoth Can and
524
00:28:38.000 --> 00:28:41.079
then several of the speaker since then has spoken about
525
00:28:41.119 --> 00:28:44.519
how important and bitle it is to bring non scientists
526
00:28:44.519 --> 00:28:48.359
together with scientists. And that's what RADFST has been very
527
00:28:48.359 --> 00:28:52.680
successful at. We've created and launched and helped and aid
528
00:28:52.759 --> 00:28:57.079
a lot of collaboration between scientists and also bring their
529
00:28:57.200 --> 00:29:00.759
science into the forefront for the people that are actually
530
00:29:00.880 --> 00:29:03.519
the consumers, the people like us, the people that are
531
00:29:03.559 --> 00:29:06.680
sitting here who want these technologies that they need to
532
00:29:06.759 --> 00:29:09.200
know that these are happening, and also people doing the
533
00:29:09.240 --> 00:29:12.599
public advocacy, like I have some people here and Dylan
534
00:29:12.759 --> 00:29:16.599
also as well. And then the People Unlimited is and
535
00:29:16.640 --> 00:29:20.480
not for it's a profit organization, and that is being
536
00:29:20.519 --> 00:29:23.839
the longest standing and most active and most successful community
537
00:29:24.319 --> 00:29:27.720
for individuals who are interested in super longevity and what
538
00:29:27.799 --> 00:29:30.279
they do and what we've done, and I've been a
539
00:29:30.279 --> 00:29:33.640
member for eighteen years. It's to bring people that are
540
00:29:33.759 --> 00:29:36.960
mostly non scientists, but bring them together and to create
541
00:29:37.079 --> 00:29:42.400
spaces of education and inspiration. And really it's been transforming
542
00:29:42.559 --> 00:29:45.160
for all of its members and all the speakers. Actually,
543
00:29:45.599 --> 00:29:49.680
Liss Perish gave her first presentation right after she got
544
00:29:49.720 --> 00:29:53.680
hur gene therapy done first People Unlimited because she was
545
00:29:53.759 --> 00:29:56.400
recommended to it. She knew and they knew that it
546
00:29:56.440 --> 00:29:59.119
was going to be the best and most supportive platform
547
00:29:59.160 --> 00:30:03.079
for her to get started on this path. So again
548
00:30:03.240 --> 00:30:05.920
I'll just be talking about how important it is to
549
00:30:05.960 --> 00:30:07.000
bring us all together.
550
00:30:07.160 --> 00:30:08.240
I do really.
551
00:30:07.960 --> 00:30:12.920
Feel that community is community and people are the scaffolding
552
00:30:13.039 --> 00:30:17.640
of longevity and super longevity medicine and the reason why
553
00:30:17.680 --> 00:30:21.000
we're doing this. And so if you know what is
554
00:30:21.039 --> 00:30:24.799
it that brought us all together, there's a little spark
555
00:30:25.000 --> 00:30:27.039
that sparked in all of us that got us interested
556
00:30:27.160 --> 00:30:30.319
enough in longevity beyond the health system that we know of,
557
00:30:30.839 --> 00:30:34.079
and so that spark and what these organizations are doing,
558
00:30:34.160 --> 00:30:37.839
it's really throwing fire at that you know, trying locks
559
00:30:37.839 --> 00:30:40.920
at that fire, and making sure that they don't extinguish themselves,
560
00:30:41.200 --> 00:30:44.680
that everybody gets seen and supported, and that there's this
561
00:30:44.799 --> 00:30:47.640
African proverb that I really like that it says, if
562
00:30:47.680 --> 00:30:50.279
you want to go fast, go alone, but if you
563
00:30:50.319 --> 00:30:52.000
want to go further, go together.
564
00:30:52.319 --> 00:30:54.160
So that's what I'm going to be talking about today.
565
00:30:55.079 --> 00:30:59.000
Fantastic And I forget to say that Mariana was also
566
00:30:59.119 --> 00:31:03.480
born in my name country, in Venezuela, and she's doing
567
00:31:03.480 --> 00:31:04.319
incredible work.
568
00:31:04.759 --> 00:31:08.880
And the next year we are going to.
569
00:31:08.880 --> 00:31:13.480
Have the Work for Longevity, the March for Longevity in Washington,
570
00:31:13.599 --> 00:31:17.799
d C. Yes, just like we had yesterday in Madrid,
571
00:31:18.480 --> 00:31:20.200
but by by.
572
00:31:20.839 --> 00:31:24.880
Very big because numbers matter and visibility matters, and having
573
00:31:25.079 --> 00:31:27.440
you know what you had yesterday, a full room of
574
00:31:27.480 --> 00:31:30.720
people here makes such a big difference rather than just
575
00:31:30.759 --> 00:31:34.559
having a few people. So imagine having hundreds of people
576
00:31:34.640 --> 00:31:38.880
marching in d C advocating for longevity rights. And like
577
00:31:39.160 --> 00:31:41.440
how we've heard from different people the option to be
578
00:31:41.480 --> 00:31:44.119
able to obtain into some of these treatments and protocols
579
00:31:44.119 --> 00:31:47.279
we've been talking about and learning about. So that is
580
00:31:47.319 --> 00:31:49.400
something that we're working on, and we'll know in a
581
00:31:49.440 --> 00:31:52.279
couple of months if it's ago, but we'll make sure
582
00:31:52.319 --> 00:31:54.480
that everybody knows what. We're very excited about it.
583
00:31:55.160 --> 00:31:57.480
So now you know you all have to come and
584
00:31:57.559 --> 00:32:01.039
join us in Washington, d C. For the March for
585
00:32:01.200 --> 00:32:05.000
Longevity in the capital of the USA and some people
586
00:32:05.039 --> 00:32:09.799
say the capital of the world. Anyway, let's finish with
587
00:32:09.799 --> 00:32:14.119
my dear friend Cody Dean, who is the global ambassador
588
00:32:14.400 --> 00:32:19.200
of a new fantastic initiative called immortali Is, and he's
589
00:32:19.200 --> 00:32:22.119
from Florida, which is a beautiful state.
590
00:32:22.319 --> 00:32:23.759
Sonny in Florida Court.
591
00:32:24.079 --> 00:32:26.640
Thank you, Jose And yes, Florida is very beautiful and
592
00:32:26.759 --> 00:32:29.000
I look forward to being at that march in Washington,
593
00:32:29.079 --> 00:32:31.319
DC next year. I hope to see many of you there.
594
00:32:31.880 --> 00:32:35.519
So I work with Immortalis, which is a global initiative.
595
00:32:35.920 --> 00:32:38.519
We're very focused right now in the United States and
596
00:32:38.720 --> 00:32:42.279
a South American country, both of which we're calling it
597
00:32:42.640 --> 00:32:45.480
Niovia to be a little bit more agreeable to a
598
00:32:45.519 --> 00:32:48.839
more conservative crowd. But what we're trying to do is
599
00:32:49.559 --> 00:32:52.880
advocate for many of you who does have more of
600
00:32:52.880 --> 00:32:57.440
that scientific background, because I don't have a scientific background,
601
00:32:57.440 --> 00:33:00.480
But what I do have is a drive to live healthy,
602
00:33:00.920 --> 00:33:04.680
much much longer than it's currently possible. So I have
603
00:33:04.839 --> 00:33:08.079
been at events like Radfest supporting you for a long
604
00:33:08.119 --> 00:33:11.440
long time. And when I finally connected with the founder
605
00:33:11.559 --> 00:33:15.079
of Immortalis Mark Hamilton, who's over here, I knew I
606
00:33:15.119 --> 00:33:18.240
had to jump on board with that because what we
607
00:33:18.279 --> 00:33:23.720
are doing to help you, help us live is it's incredible.
608
00:33:23.960 --> 00:33:27.480
What we're trying to do is unlock the funding that
609
00:33:27.559 --> 00:33:31.279
so many of you desperately need. And part of the
610
00:33:31.319 --> 00:33:35.319
way we're doing that is by accelerating some of the
611
00:33:35.359 --> 00:33:39.559
regulatory pathways that are slowing things down. So when that happens,
612
00:33:39.839 --> 00:33:44.680
investors will begin to see a better return on their investment,
613
00:33:44.839 --> 00:33:49.440
both in profit margin and in timeline, and so you'll
614
00:33:49.440 --> 00:33:54.440
see an influx of investment opportunity into you into what
615
00:33:54.480 --> 00:33:57.960
you're doing when we successfully unlock a zone, and you'd
616
00:33:57.960 --> 00:34:01.680
be surprised how close we are, even within the United States,
617
00:34:01.680 --> 00:34:05.480
which has been historically tough to get into. So you know,
618
00:34:05.519 --> 00:34:09.320
stay tuned for what's happening there could potentially be you know,
619
00:34:09.440 --> 00:34:11.440
the end of the year early in the next year.
620
00:34:11.760 --> 00:34:16.840
You know, politics is a very interesting landscape, so we'll see.
621
00:34:17.320 --> 00:34:20.840
But once that is unlocked and you're able to come
622
00:34:20.880 --> 00:34:25.440
in and do what you do much much faster and
623
00:34:25.880 --> 00:34:31.400
with more funding behind you and still cheaper, you're going
624
00:34:31.440 --> 00:34:33.559
to be able to save our lives faster, which is
625
00:34:33.599 --> 00:34:35.159
selfishly what I want.
626
00:34:35.679 --> 00:34:41.639
So that's us fantastic Cody, and now I want to
627
00:34:41.679 --> 00:34:45.320
go into a second round to see what they are
628
00:34:45.360 --> 00:34:49.159
doing on their background is related to public advocacy because
629
00:34:49.239 --> 00:34:53.679
part of the International Longevity Summit is to have an impact,
630
00:34:53.800 --> 00:34:56.559
an impact on people, and you have seen we have
631
00:34:56.679 --> 00:35:00.320
had two documentaries. We have been in all all the
632
00:35:00.400 --> 00:35:03.800
media in Spain, you know, the media soon attacking us
633
00:35:03.800 --> 00:35:08.039
by the way, they cannot understand that we believe that
634
00:35:08.119 --> 00:35:11.360
this is science and technology that we are going to
635
00:35:11.440 --> 00:35:16.719
be able to live longer, healthier, better. So I don't
636
00:35:16.800 --> 00:35:19.679
understand how some people can attack this beautiful idea.
637
00:35:19.800 --> 00:35:21.719
But anyway, we are in all media, so.
638
00:35:21.639 --> 00:35:25.320
This is fantastic, all TVs, radio, newspapers. We had the
639
00:35:25.360 --> 00:35:28.440
major of Madrid, I mean we can go much higher,
640
00:35:28.639 --> 00:35:32.320
who is a very important person. And we had the
641
00:35:32.400 --> 00:35:36.480
March for Longevity. We had a lot of things going on,
642
00:35:36.559 --> 00:35:39.440
and we have fantastic speakers in all sessions, including these
643
00:35:39.480 --> 00:35:44.039
beautiful planet So how can we move the movement forward?
644
00:35:44.920 --> 00:35:48.280
How can we impact? So this is the main idea that.
645
00:35:48.559 --> 00:35:53.960
Appears when a Parina Athinia was born. So in escent
646
00:35:54.039 --> 00:35:57.840
Tom which is the vice president, myself and some other scientists,
647
00:35:57.920 --> 00:36:00.800
we wanted really to have an impact, not only with
648
00:36:00.920 --> 00:36:04.440
our research, but also to tell the society how important
649
00:36:04.559 --> 00:36:08.480
is science. So if you pay attention to the richest
650
00:36:08.480 --> 00:36:13.079
countries and the best countries in the world are those
651
00:36:13.159 --> 00:36:17.840
which have invested a lot of money in science, and
652
00:36:17.880 --> 00:36:21.360
because of these results that appeal. Finally they have an
653
00:36:21.400 --> 00:36:25.440
impact and finally the society can really feel the impact
654
00:36:25.480 --> 00:36:29.119
of this research. Something important that I would like to
655
00:36:29.199 --> 00:36:34.079
mention is the importance of do research, do investigation in
656
00:36:34.320 --> 00:36:38.960
every areas of knowledge. So the challenges we have in
657
00:36:39.000 --> 00:36:42.480
front of us in this century and in the centuries
658
00:36:42.559 --> 00:36:46.760
are really important and very big, and only through the
659
00:36:46.840 --> 00:36:52.000
collaboration and interdisciplinarity of all areas of knowledge we can
660
00:36:52.119 --> 00:36:56.000
give an answer to this to solve these problems. So
661
00:36:56.599 --> 00:37:01.519
this is also something that we really focus on when
662
00:37:01.559 --> 00:37:04.280
we are working in a paternal latentia.
663
00:37:04.760 --> 00:37:07.719
And this makes also very singular.
664
00:37:07.519 --> 00:37:12.519
Our associations, so you maybe see another different foundations, many
665
00:37:12.559 --> 00:37:16.800
different associations that pay attention to one specific subject.
666
00:37:17.159 --> 00:37:19.880
In a paternal athentia, we pay attention to all.
667
00:37:19.880 --> 00:37:23.599
Areas of knowledge and this is something singular and also
668
00:37:23.679 --> 00:37:28.519
as strength. Another singular part of patental things and one
669
00:37:28.559 --> 00:37:31.079
of our strengths is that is leaded.
670
00:37:30.719 --> 00:37:32.880
And directed by scientists.
671
00:37:33.360 --> 00:37:37.920
So we are used to manage our group, lead our
672
00:37:37.960 --> 00:37:43.000
group research groups and also we manage the We get
673
00:37:43.039 --> 00:37:47.159
funding from many different funding agencies, not only national but
674
00:37:47.199 --> 00:37:51.159
also international, and we know really which are the problems
675
00:37:51.519 --> 00:37:55.159
and we know very well how with very little amount
676
00:37:55.239 --> 00:37:57.480
of money to have an impact.
677
00:37:57.159 --> 00:37:58.039
In our research.
678
00:37:58.880 --> 00:38:02.599
That's why all the fundly we got we made open
679
00:38:02.679 --> 00:38:06.960
calls and they have all the projects we receive, all
680
00:38:07.119 --> 00:38:11.000
all the proposals are evaluated by scientists. That's why they
681
00:38:11.039 --> 00:38:15.199
impact each much higher. So this is something that I
682
00:38:15.239 --> 00:38:18.199
will want to share you because if you put money
683
00:38:18.280 --> 00:38:22.199
in you, if you make a donation to a Padina Latinia,
684
00:38:22.480 --> 00:38:25.199
you can be sure that all these money are going
685
00:38:25.239 --> 00:38:28.559
to be optimized. It's not a waste of money, but
686
00:38:28.679 --> 00:38:32.400
an investment in science, an investment to get results and
687
00:38:32.559 --> 00:38:36.840
finally an investment to get an impact in the society.
688
00:38:38.599 --> 00:38:40.559
Thank you so stell here.
689
00:38:40.920 --> 00:38:43.679
So I prepare these graphics as I've been doing for
690
00:38:43.719 --> 00:38:47.039
these conferences for the last few years. My name is,
691
00:38:47.199 --> 00:38:50.280
as I said, Sergio Martinaterero, and I'm producing all these
692
00:38:50.360 --> 00:38:54.239
videos on the streaming partly as a donation of a tourista.
693
00:38:54.559 --> 00:38:57.000
I'll let you know that we're changing the logo. It's
694
00:38:57.000 --> 00:39:02.719
a political party. I discussed and fired on these stages
695
00:39:02.760 --> 00:39:06.519
of life picture. We just took you know, the part
696
00:39:06.559 --> 00:39:09.800
after aging, because otherwise it would be too big of
697
00:39:09.880 --> 00:39:12.599
us a logo. But I lived up there for now,
698
00:39:13.239 --> 00:39:16.159
and yes I've covered just as part of this two
699
00:39:16.199 --> 00:39:19.559
thousand and eight, Transmission, twenty one, twenty two, twenty four,
700
00:39:19.840 --> 00:39:23.559
twenty five. Now my friends Jose David Wood and many
701
00:39:23.559 --> 00:39:27.199
others go back over twenty years when I started documenting
702
00:39:27.239 --> 00:39:31.119
events like the Forssight Institute conferences, then Transition two thousand
703
00:39:31.159 --> 00:39:34.159
and six in Helsinki, twenty seven in Chicago with Charlie
704
00:39:34.199 --> 00:39:36.639
cam I don't know if it's still here, and many
705
00:39:36.639 --> 00:39:39.960
other such events. When I was growing up, I was
706
00:39:40.079 --> 00:39:44.039
very concerned about the Cold War in the eighties. This
707
00:39:44.239 --> 00:39:48.760
movie Wargames really touched me, and I thought very good
708
00:39:48.800 --> 00:39:52.800
movies about important subjects could really change the world and
709
00:39:53.000 --> 00:39:56.800
educate people. And everybody gets to hear about ideas to
710
00:39:56.880 --> 00:40:00.480
the end of the world. Everybody knows Rocky Balb and
711
00:40:00.519 --> 00:40:04.360
the Terminator, and you can really reach out with the
712
00:40:04.360 --> 00:40:08.320
film medium. So when I was growing up, I thought
713
00:40:08.320 --> 00:40:10.760
it was easier to influence the world through movies than
714
00:40:11.480 --> 00:40:13.920
doing politics. I had never thought about going into politics
715
00:40:14.000 --> 00:40:14.960
until much much.
716
00:40:14.800 --> 00:40:18.559
Later, many many years later.
717
00:40:19.239 --> 00:40:22.280
In two thousand and two or so, I was studying
718
00:40:22.280 --> 00:40:24.400
how the Best incorporated the idea of my medical evolution
719
00:40:24.559 --> 00:40:28.400
into a script. I inadvertently discovered transhumanism and the prospect
720
00:40:28.440 --> 00:40:33.159
for molecular technology artificial superintelligence changing the world drastically in
721
00:40:33.199 --> 00:40:36.760
a matter of a future decades. I decided to get
722
00:40:36.800 --> 00:40:40.519
involved and to get informed, and to see what I
723
00:40:40.519 --> 00:40:44.679
could do to help this movement to get us there
724
00:40:44.800 --> 00:40:49.000
quicker but safer. I realized that the issues regarding these
725
00:40:49.079 --> 00:40:53.920
ultra technologies like molecular nanotechnology and superintelligence were so grave
726
00:40:54.679 --> 00:40:57.920
and so urgent, while at the same time so promising
727
00:40:57.960 --> 00:41:00.360
and liberating, that I should focus more on how I
728
00:41:00.360 --> 00:41:03.639
could influence their positive development while avoiding the worst risks.
729
00:41:04.239 --> 00:41:07.039
Ever since, I have you know, recorded all these conferences
730
00:41:07.119 --> 00:41:08.960
as part of my effort to help brow the movement
731
00:41:09.400 --> 00:41:12.840
from all the ideas and make the videos look good
732
00:41:12.880 --> 00:41:17.239
hopefully or better every year, and just to document them
733
00:41:17.239 --> 00:41:20.920
for the record. After twenty ten or so, my thoughts
734
00:41:20.960 --> 00:41:23.079
about super moral ais made me give a lot of
735
00:41:23.119 --> 00:41:25.920
thoughts to the Way with three Animals, and I got
736
00:41:26.159 --> 00:41:29.679
interested in animal ethics just to make friends and stuff
737
00:41:29.719 --> 00:41:32.880
and to learn about it. I volunteered for an animal
738
00:41:33.000 --> 00:41:36.239
rights political party, PATMA, and part of the animalist at
739
00:41:36.239 --> 00:41:39.039
PATMA here in Spain for about a year. Then I
740
00:41:39.199 --> 00:41:42.559
realized that something was missing in this party and basically
741
00:41:42.639 --> 00:41:46.000
in every other political party which is a strong feminist component.
742
00:41:47.880 --> 00:41:51.719
I'd witness political debates within the movement for about a decade.
743
00:41:52.599 --> 00:41:57.599
They're very interesting and you know, enlightening and edifying, but
744
00:41:59.119 --> 00:42:02.840
there was any being done. So I decided to start
745
00:42:02.840 --> 00:42:05.239
the first political party with a few friends here in Spain.
746
00:42:05.840 --> 00:42:08.880
Founding it was easy. Then we had to develop the
747
00:42:08.920 --> 00:42:11.440
ideas further and it took time. It took years to
748
00:42:11.480 --> 00:42:14.119
really develop our declaration of principles from a small document
749
00:42:14.159 --> 00:42:19.440
into what it is today and we continued recording videos
750
00:42:19.440 --> 00:42:22.880
and conferences are in twenty fourteen with an AI conference
751
00:42:22.920 --> 00:42:27.039
in Santander were for later organized as well, and just
752
00:42:27.199 --> 00:42:31.000
continued Crionist conferences and this and that, just many many things.
753
00:42:31.280 --> 00:42:35.159
We had an unfortunate passing in the party, Havier with
754
00:42:35.360 --> 00:42:39.320
the past, and we managed to honor his will of
755
00:42:39.360 --> 00:42:44.239
getting him cryonically preserved. But yeah, the party kind of
756
00:42:44.239 --> 00:42:48.880
revived and got new people in. And we also have a,
757
00:42:49.039 --> 00:42:51.519
like I said, a strong animal latist component, and other
758
00:42:51.559 --> 00:42:56.880
dimensions of political discussion that go beyond life extension. We're
759
00:42:56.920 --> 00:43:01.800
also extremely concerned with big global catastrophic risk existential risks
760
00:43:01.800 --> 00:43:05.239
that certain technologies could bring about, and so our Declaration
761
00:43:05.280 --> 00:43:08.920
of principles grew. Let me see if I have just
762
00:43:09.159 --> 00:43:11.280
an image of it. You should take a look at
763
00:43:11.320 --> 00:43:15.159
the document yourself. Yeah, it's from something small to something
764
00:43:15.360 --> 00:43:18.519
that's something like twenty five pages long today, and it's
765
00:43:18.800 --> 00:43:21.000
we're pretty proud of it, and we wrote it every
766
00:43:21.199 --> 00:43:22.920
few months. We have a new update. The last one
767
00:43:23.000 --> 00:43:25.079
is just a few days old, so feel free to
768
00:43:25.079 --> 00:43:33.280
take a look. Yeah, and I would like to read
769
00:43:33.320 --> 00:43:36.320
briefly Kennedy's historian offs from Mars. In a recent email
770
00:43:36.559 --> 00:43:40.280
from the Transhumitist Party in the US, he wrote this
771
00:43:41.320 --> 00:43:43.519
short text. It's nice, so I'll just read it for you.
772
00:43:43.840 --> 00:43:46.719
Aleantha Fatriista and the US Transumitist Party are the true
773
00:43:46.840 --> 00:43:50.280
oldest transhumanist political parties in the world. We have endured
774
00:43:50.320 --> 00:43:52.679
because we are guided by long term goals and enduring
775
00:43:52.760 --> 00:43:56.880
vision of our transhumanist pursuits and transform the human condition
776
00:43:57.000 --> 00:43:59.880
for the better, rather than focusing narrowly on winning election
777
00:44:00.239 --> 00:44:04.039
or beating other political parties. Ultimately, transhumanism is a global
778
00:44:04.039 --> 00:44:07.119
movement that leads to unite humans in our share aspiration
779
00:44:07.360 --> 00:44:13.039
to overcome all age limits of mortality, disease, materialscustody, and irrationality. Therefore,
780
00:44:13.039 --> 00:44:16.280
political success of trust humanists anywhere in the world is
781
00:44:16.320 --> 00:44:19.159
a success for trusumanist everywhere in the world. Any jurisdiction
782
00:44:19.320 --> 00:44:23.239
where transhumanism succeeds in influencing government policy in a direction
783
00:44:23.280 --> 00:44:26.039
that is more open to technological advancement will be a
784
00:44:26.119 --> 00:44:31.360
jurisdiction where research breakthroughs courrecture to benefit humanity. The US
785
00:44:31.519 --> 00:44:34.559
TP considers aliataa Trista to be its key ally in Spain,
786
00:44:34.679 --> 00:44:37.199
and we are eager to see what its efforts can
787
00:44:37.199 --> 00:44:39.679
accomplished to enable Spain to become one of the foremost
788
00:44:40.000 --> 00:44:44.400
prolengevity countries of our time. Ali Asafadrista is welcome. This
789
00:44:44.480 --> 00:44:47.159
has to do with our suggestion that we would sign
790
00:44:47.320 --> 00:44:52.559
their values document and that in our declarations they have
791
00:44:52.639 --> 00:44:57.440
the Transhumitist Party Values and Trushumanists Bill of Rights, and
792
00:44:57.480 --> 00:45:00.159
so we already passed it in our party work sign
793
00:45:00.239 --> 00:45:02.119
this declaration and will add it to this part of
794
00:45:02.199 --> 00:45:05.159
the website in the next few days. It's an announcement
795
00:45:05.199 --> 00:45:09.159
I'm making as more of an interconnection between our two
796
00:45:09.199 --> 00:45:14.199
parties because we should really strongly support each other. And yeah,
797
00:45:14.800 --> 00:45:19.679
now just briefly, I would like to I would like
798
00:45:19.719 --> 00:45:22.159
you all and everyone you know to help these parties,
799
00:45:22.159 --> 00:45:24.000
to help Alianta to this die if you can to
800
00:45:24.039 --> 00:45:27.880
get involved, to get to get to know us, and
801
00:45:29.119 --> 00:45:32.960
there's memberships, there's you can make donations. There's a pretty
802
00:45:33.039 --> 00:45:35.960
high limit in Spain for donations, so if anyone has money,
803
00:45:36.159 --> 00:45:40.159
it can help us grow much faster, and especially human
804
00:45:40.679 --> 00:45:45.639
force human you know members, especially within Spain, so I
805
00:45:45.679 --> 00:45:47.880
know some of you are Spanish or people in Spain
806
00:45:47.920 --> 00:45:51.280
are watching through the subtitles et cetera. So we need
807
00:45:51.440 --> 00:45:54.719
people to have the different areas of the party. If
808
00:45:54.760 --> 00:45:59.480
you like, if yours, especially an expert on any of
809
00:45:59.519 --> 00:46:01.800
the fields we talk about, come to us so you
810
00:46:01.840 --> 00:46:04.280
can head one of the departments or something like that.
811
00:46:05.000 --> 00:46:08.320
And yeah, that's basically. I don't know if I have anymoreuslightes.
812
00:46:08.639 --> 00:46:10.760
We were showing the Bill of Rights and all of
813
00:46:10.800 --> 00:46:13.400
these things briefly, but yeah, there's a code if you
814
00:46:13.440 --> 00:46:15.079
want to reach the website quicker.
815
00:46:15.719 --> 00:46:19.639
Thank you, okay, thank you Serkio for all you are doing.
816
00:46:20.000 --> 00:46:24.360
And now we want to bring back the beautiful, the intelligent,
817
00:46:24.559 --> 00:46:27.639
the expert on all of this, Sabini.
818
00:46:28.800 --> 00:46:29.599
Thank you, thank you.
819
00:46:30.280 --> 00:46:31.639
So are you all energized?
820
00:46:32.239 --> 00:46:37.559
Yes, yes, well we have a little energy left.
821
00:46:37.639 --> 00:46:39.079
We're going to have a few more speakers.
822
00:46:39.079 --> 00:46:41.840
Look at this eminent speaker panel sitting here, it's amazing.
823
00:46:42.239 --> 00:46:44.840
I want to start off by introducing our next speaker,
824
00:46:45.079 --> 00:46:48.239
who really has many engagements in longevity. Two of them
825
00:46:48.360 --> 00:46:52.480
are as CEO of Balerno, the largest longevity clinic in
826
00:46:52.639 --> 00:46:56.599
Europe that can host up to fifteen thousand patients, and also.
827
00:46:56.440 --> 00:46:57.920
CEO pro Jevita.
828
00:46:58.039 --> 00:47:01.360
I hope I can announce that a longevity retreat that
829
00:47:01.440 --> 00:47:04.639
then is more geared towards business people and C suites.
830
00:47:05.000 --> 00:47:08.239
And she's also the co founder of our ex Longevity,
831
00:47:08.280 --> 00:47:11.719
a longevity coach app so she is truly, truly well
832
00:47:11.800 --> 00:47:13.920
versed in the longevity space. Please give it up for
833
00:47:14.000 --> 00:47:22.360
Clara Fernandez Porta.
834
00:47:24.559 --> 00:47:29.039
Hi, everyone, So when Jose asked me to talk about
835
00:47:29.480 --> 00:47:33.639
public advocacy and how our clinic or our model was
836
00:47:33.719 --> 00:47:37.559
working to help push the longevity science, I was very
837
00:47:37.559 --> 00:47:39.800
happy to be here and be able to share you
838
00:47:40.039 --> 00:47:44.039
how I have actually designed the clinic to make sure
839
00:47:44.119 --> 00:47:47.599
that we could become a tool for society, for both
840
00:47:47.760 --> 00:47:52.239
patients and scientists to push up longevity as much as possible.
841
00:47:52.599 --> 00:47:56.480
So I have some slices. So just before you understand
842
00:47:56.519 --> 00:47:58.280
and I'm gonna talk, I'm gonna be I have a
843
00:47:58.320 --> 00:48:01.119
short presentation, but just be or I started telling you
844
00:48:01.519 --> 00:48:04.039
a little bit more about my clinic, I want to
845
00:48:04.039 --> 00:48:07.559
give you some context. So we're in Valencia, in the
846
00:48:07.599 --> 00:48:10.679
middle of the forest. We have over two million square
847
00:48:10.719 --> 00:48:14.400
meters in the middle of the forest, over eighty different buildings.
848
00:48:14.880 --> 00:48:18.880
It is traditionally a historical thermal clinic, which in Europe
849
00:48:18.920 --> 00:48:22.519
is very popular. So it was originally created to create
850
00:48:22.719 --> 00:48:26.360
natural medicine treatment, but over the last thirty years the
851
00:48:26.440 --> 00:48:29.719
company has evolved in the area of healthy aging and
852
00:48:29.800 --> 00:48:33.440
health and longevity. So the company is actually founded by
853
00:48:33.880 --> 00:48:36.199
it's a family company, so it's founded by my father
854
00:48:36.559 --> 00:48:40.119
who is here a doctor, and as a family company,
855
00:48:40.159 --> 00:48:43.079
we have been able to decide and create the strategy
856
00:48:43.119 --> 00:48:45.599
that we thought would have the biggest impact in society.
857
00:48:46.280 --> 00:48:50.559
We are initially focused on people from sixty to seventy
858
00:48:50.639 --> 00:48:55.639
years because we believe that's in the longevity clinic ecosystem.
859
00:48:55.679 --> 00:48:59.840
We believe that is the unique segment that has time
860
00:49:00.559 --> 00:49:05.480
and willingness to dedicate themselves to that to longevity treatments,
861
00:49:06.320 --> 00:49:08.559
and so that has enabled us to create a model
862
00:49:08.880 --> 00:49:11.719
where patients come every day. We have an average of
863
00:49:11.800 --> 00:49:15.440
sixty patients coming every day for ten days staying with us,
864
00:49:15.679 --> 00:49:20.119
with six hundred patients as I mentioned, staying with us together.
865
00:49:20.320 --> 00:49:23.159
And we have been able to create a framework of
866
00:49:23.280 --> 00:49:29.320
treatments that I've been able to democratize longevity treatments. So anyway,
867
00:49:29.320 --> 00:49:31.159
what I was going to tell you is how we
868
00:49:31.239 --> 00:49:33.599
actually have created the ecosystem, because I think it's very
869
00:49:33.679 --> 00:49:37.719
unique and very different to most of the other longevity clinics,
870
00:49:37.719 --> 00:49:41.559
and that has been the core element that has given us.
871
00:49:41.039 --> 00:49:42.599
The unique advantage to.
872
00:49:42.559 --> 00:49:46.280
Both skill or super great. So here you can have
873
00:49:46.360 --> 00:49:50.360
my information also my website. So first of all, the
874
00:49:50.400 --> 00:49:53.559
most important thing that is different, Okay, I told you
875
00:49:53.599 --> 00:49:55.280
so we have an average of one hundred and sixty
876
00:49:55.320 --> 00:49:59.519
thousand patients per year daily patients. That makes us and
877
00:49:59.559 --> 00:50:02.599
the biggest hotel in the province of Valencia, which is
878
00:50:02.639 --> 00:50:06.519
a very touristic hotel. But what actually has the scale
879
00:50:06.519 --> 00:50:09.599
and number of patients has given us is the possibility
880
00:50:09.679 --> 00:50:13.599
to create accessible treatments. And why is this. Most of
881
00:50:13.599 --> 00:50:18.800
the traditional longevity techniques that you know have a smaller scale,
882
00:50:18.800 --> 00:50:21.039
and that makes that most of the cost of the
883
00:50:21.079 --> 00:50:24.840
treatments are not necessarily uniquely the cost of medicine per se,
884
00:50:25.239 --> 00:50:28.280
but the cost of the set up. So being big
885
00:50:28.760 --> 00:50:31.960
is for us from a fundamental part of being able
886
00:50:32.000 --> 00:50:35.760
to have a big scientific a big medical team, a
887
00:50:35.800 --> 00:50:39.239
big scientific team and make sure that we can deliver
888
00:50:39.440 --> 00:50:44.159
treatments at the unique marginal cost in terms of treatments.
889
00:50:44.400 --> 00:50:46.960
Just so that you know, we're strong on red generative
890
00:50:47.000 --> 00:50:51.480
medicine and anti inflammation protocols and patients can either come
891
00:50:51.519 --> 00:50:53.880
to one of our set protocols that is a combination
892
00:50:54.000 --> 00:51:00.119
of stem cell treatments or themolecular medicines, plasma therasis, ozone therapy,
893
00:51:00.519 --> 00:51:03.719
or they can come to one of our personalized protocols.
894
00:51:04.360 --> 00:51:08.320
All of our treatments do a combination of diagnostics, treatments,
895
00:51:08.519 --> 00:51:11.719
and education. And this is also a very important part
896
00:51:11.400 --> 00:51:15.079
that I want to make points on, especially as we're
897
00:51:15.079 --> 00:51:19.039
speaking about public advocacy. Every patient that comes to our
898
00:51:19.079 --> 00:51:24.079
clinic has an average of twenty hours of longevity master classes.
899
00:51:24.639 --> 00:51:27.440
We are making sure that everyone that comes to our
900
00:51:27.519 --> 00:51:32.960
space understands the biology of aging, not only what's available today.
901
00:51:33.199 --> 00:51:38.000
We don't do this education or scientific master classes to
902
00:51:38.360 --> 00:51:43.199
get them more treatments. For us, it is fundamental that
903
00:51:43.320 --> 00:51:47.599
people understand the biology of their aging process and what
904
00:51:47.800 --> 00:51:49.880
is to come in the next years, because we believe
905
00:51:49.960 --> 00:51:52.360
that is the unique way that they're going to spread
906
00:51:52.400 --> 00:51:55.000
the word and that they are going to have an
907
00:51:55.000 --> 00:52:01.039
interest in taking care of their health. Yes, with raker Cell,
908
00:52:01.320 --> 00:52:04.000
he told us in the presentation that he believes that
909
00:52:04.079 --> 00:52:06.800
in just seven years when we might reach the longevity
910
00:52:06.840 --> 00:52:11.199
velocity of escape. Well, that's fundamental that we teach society
911
00:52:11.400 --> 00:52:15.360
because people are not going to take longevity treatments or
912
00:52:15.400 --> 00:52:18.480
their health strategy in the same way if they believe
913
00:52:18.519 --> 00:52:22.760
we are very far from having any impactful results in
914
00:52:22.800 --> 00:52:26.440
our lives, or whether they think that is actually relatively close.
915
00:52:26.719 --> 00:52:30.480
So economiest of skill enables us to have not only
916
00:52:30.719 --> 00:52:33.159
great treatments delivered to the patient, but also to do
917
00:52:33.760 --> 00:52:37.119
very specific master classes and make sure that we invest
918
00:52:37.960 --> 00:52:42.360
in creating the education and the culture that we need
919
00:52:42.400 --> 00:52:47.320
the patients to demand. Finally, because we have a lot
920
00:52:47.320 --> 00:52:49.920
of patients, we have a lot of data. So it's
921
00:52:49.960 --> 00:52:53.559
been almost I think eight years that we decided that
922
00:52:54.079 --> 00:52:57.000
one of the biggest roles that we could have in
923
00:52:57.039 --> 00:53:01.480
the longevity ecosystem was to become a plaque a platform
924
00:53:01.480 --> 00:53:05.559
from scientists, for universities and for companies so that they
925
00:53:05.599 --> 00:53:11.239
could actually research with our patient data, iterate their producals
926
00:53:11.480 --> 00:53:15.360
with our patients, and finally be able to test the
927
00:53:15.400 --> 00:53:19.480
final results. The Human Lab is a space where we
928
00:53:19.519 --> 00:53:23.199
do clinical trials, but it's also a place where we
929
00:53:23.320 --> 00:53:27.639
gather data for patients that we open for the science community,
930
00:53:27.920 --> 00:53:29.440
just so you get a little bit of a scale.
931
00:53:29.519 --> 00:53:32.440
This year we have had two point five million euros
932
00:53:32.480 --> 00:53:36.239
in grants from government from Spain and from Europe. In
933
00:53:36.360 --> 00:53:40.159
protocols that we have designed ourselves. We expect next year
934
00:53:40.199 --> 00:53:42.559
to have more than three million and to double the
935
00:53:42.639 --> 00:53:45.559
number of PhD students that are using our data to
936
00:53:45.679 --> 00:53:49.639
publish scientific research. Also, we have created a model that
937
00:53:49.679 --> 00:53:54.960
it's a digital biobank by which patients can actually leave
938
00:53:55.000 --> 00:53:59.079
their data accessible for science. The data is going to
939
00:53:59.119 --> 00:54:02.599
be sold different startups or companies, and that money is
940
00:54:02.639 --> 00:54:05.320
going to be used as a unique wallet for the
941
00:54:05.400 --> 00:54:09.079
patient that they can reinvest in their longevity treatments for
942
00:54:09.199 --> 00:54:11.639
next year. I didn't mention this, but most of our
943
00:54:11.679 --> 00:54:15.519
patients from every year, the protocols that we design are
944
00:54:15.719 --> 00:54:17.880
designed to be a pit stop, an animal pit stop.
945
00:54:18.239 --> 00:54:21.000
So they come every year, get checked up again, get
946
00:54:21.000 --> 00:54:24.280
boosted with their motivation and their classes, what's happening in
947
00:54:24.280 --> 00:54:27.880
in the biology of aging, make sure that they are
948
00:54:27.920 --> 00:54:31.119
on the right track, redesign their plan and go back home.
949
00:54:31.960 --> 00:54:36.519
So and finally, a human LAP is not just great
950
00:54:36.559 --> 00:54:40.719
because we can push science, but because having access to
951
00:54:40.800 --> 00:54:44.920
clinical trials enables us to deliver unique treatments under the
952
00:54:45.000 --> 00:54:48.480
umbrella of clinical trials. So being in contact with the
953
00:54:48.519 --> 00:54:52.239
scientific community is not just great to push the science,
954
00:54:52.599 --> 00:54:55.000
but it also is the unique way to help us
955
00:54:55.679 --> 00:54:58.239
be on the bank guard of what's happening in longevity.
956
00:54:58.679 --> 00:55:01.559
So this isn't because of because it actually feeds himself
957
00:55:01.599 --> 00:55:04.480
being able to have more clinical trials and unique clients.
958
00:55:04.480 --> 00:55:07.599
It's actually what gives us the more patient base and
959
00:55:07.639 --> 00:55:09.880
more people that are willing to come year after year,
960
00:55:09.920 --> 00:55:12.320
which gives us more economies of scale and more data.
961
00:55:13.320 --> 00:55:15.880
So this was basically the model I wanted to share,
962
00:55:15.920 --> 00:55:17.760
and I think it's very relevant because most of the
963
00:55:17.760 --> 00:55:21.199
longevitic clinics are not articulated in a way in which
964
00:55:21.239 --> 00:55:25.199
they're interrelated to the scientific community, not just the science
965
00:55:25.239 --> 00:55:28.519
that they're pushing themselves, but the general scientific community. And
966
00:55:28.559 --> 00:55:31.039
I think this is a very important message to be
967
00:55:31.079 --> 00:55:34.559
spread more of FAST could be making more treatments, more
968
00:55:34.559 --> 00:55:41.760
democratized and having a bigger impact in society.
969
00:55:48.199 --> 00:55:48.960
Thank you, Clark.
970
00:55:49.079 --> 00:55:51.960
Really interesting to see as an ecosystem thinker, I mean
971
00:55:51.960 --> 00:55:55.039
I found it very interesting. And our next speaker is
972
00:55:55.119 --> 00:55:58.920
CEO for Digital for Health Worldwide and president of mad
973
00:55:59.000 --> 00:56:03.119
eHealth flagship initiated and backed by Madrid City.
974
00:56:02.920 --> 00:56:05.360
Council, and his lifelong mission is.
975
00:56:05.280 --> 00:56:09.000
To really re architect healthcare around the patient, so be
976
00:56:09.119 --> 00:56:14.480
patient centric, fusing public and private integration, open innovation, and
977
00:56:14.559 --> 00:56:18.320
also AI into everyday care and digital health. And with that,
978
00:56:18.400 --> 00:56:22.199
I'd like to hand the word over to Carlos dis Lsa.
979
00:56:23.320 --> 00:56:24.039
Thank you so much.
980
00:56:31.159 --> 00:56:33.920
I have shared something very important with you guys a
981
00:56:33.920 --> 00:56:36.519
few minutes ago. You remember when I told you I
982
00:56:36.559 --> 00:56:41.280
was a very bad student brings a bell. I was
983
00:56:41.320 --> 00:56:44.320
a horrible student. Actually I lied to you. It was horrible,
984
00:56:44.440 --> 00:56:48.199
not bad. But I was doing something, you know, what
985
00:56:48.320 --> 00:56:52.119
I was doing very well, just one thing. Can you
986
00:56:52.159 --> 00:56:58.400
think of what I was doing, just one thing, dreaming
987
00:57:00.679 --> 00:57:03.800
one thing and trying to do it well. So I
988
00:57:03.840 --> 00:57:09.119
spent hours, if you think of university long hours, long studies,
989
00:57:10.360 --> 00:57:13.559
so I spent long hours, as all of you did,
990
00:57:13.639 --> 00:57:18.280
probably dreaming. And today I'm going to share with you,
991
00:57:18.360 --> 00:57:21.960
hopefully one of my last dreams. I've had a lot
992
00:57:21.960 --> 00:57:24.760
of nightmares by the way, also, but this is one
993
00:57:24.800 --> 00:57:26.960
of my last dreams that I have shared with you before.
994
00:57:27.039 --> 00:57:31.199
So this video is a very simple example of what
995
00:57:31.280 --> 00:57:35.960
I dreamed eight years ago, when, as I said before,
996
00:57:36.000 --> 00:57:40.280
we were trying to put together public and private sectors
997
00:57:40.920 --> 00:57:43.840
because we all think that healthcare doesn't have to be
998
00:57:43.920 --> 00:57:44.920
public or private.
999
00:57:45.079 --> 00:57:46.239
It has to be good.
1000
00:57:47.280 --> 00:57:51.000
And as far as I know, the only possible way
1001
00:57:51.119 --> 00:57:55.599
for us to deliver a very good healthcare healthcare system
1002
00:57:55.719 --> 00:58:01.639
is by unifying, putting together both sectorsublic and private. Let
1003
00:58:01.719 --> 00:58:03.880
maybe before we see the video, just say this a
1004
00:58:04.000 --> 00:58:05.320
very little piece of thought.
1005
00:58:06.159 --> 00:58:08.519
So you know healthcare systems.
1006
00:58:08.760 --> 00:58:11.719
So public is probably seventy percent of the total in
1007
00:58:11.800 --> 00:58:15.679
volumes in values. But we need a private and private
1008
00:58:15.760 --> 00:58:41.559
needs public. Are we ready, so let's go for it? Well,
1009
00:58:41.679 --> 00:58:42.480
there is no noise.
1010
00:58:45.480 --> 00:58:46.000
Yes, there is.
1011
01:01:37.920 --> 01:01:44.440
Gee that gave me so.
1012
01:01:47.039 --> 01:01:51.320
Come back, gave you.
1013
01:01:50.119 --> 01:01:50.800
Say it all.
1014
01:01:59.519 --> 01:02:09.639
And thank you so much.
1015
01:02:09.920 --> 01:02:14.719
So this is, as I said before, our last but
1016
01:02:14.880 --> 01:02:19.280
not least dream. We keep dreaming. This is the first
1017
01:02:19.280 --> 01:02:23.880
digital city in the world. We have two campuses. Eight
1018
01:02:23.880 --> 01:02:27.519
thousand square meters is the first one, more than one
1019
01:02:27.599 --> 01:02:30.719
hundred square meters for the second one. We have invested
1020
01:02:30.719 --> 01:02:33.159
more than six hundred million euros, which is a lot
1021
01:02:33.159 --> 01:02:37.719
of money. We are welcoming and I am in discussions
1022
01:02:37.760 --> 01:02:44.039
with the owner of this event, with mister Cordeo, because
1023
01:02:44.079 --> 01:02:48.119
I would really love to keep dreaming, and I dare you,
1024
01:02:49.079 --> 01:02:50.639
all of you to keep dreaming.
1025
01:02:50.800 --> 01:02:52.079
I would like to make.
1026
01:02:52.159 --> 01:02:58.760
This city the center of the European longevity world. We
1027
01:02:58.800 --> 01:03:03.079
should think of it. Nothing stops us from thinking and
1028
01:03:03.159 --> 01:03:08.519
from dreaming. So this is our contribution. You were asking before, Louis,
1029
01:03:09.000 --> 01:03:11.960
what is our contribution to this longevity. I am not
1030
01:03:12.039 --> 01:03:14.480
a doctor. I was a Hord student, as I told
1031
01:03:14.480 --> 01:03:18.800
you many times. But we think that putting together private
1032
01:03:18.840 --> 01:03:23.880
and public is fundamental. Dreaming is fundamental. Integrating all stakeholders
1033
01:03:24.400 --> 01:03:28.199
is fundamental. As I said before, we are not in
1034
01:03:28.400 --> 01:03:31.880
heathcare only one. There is no one decision maker. We
1035
01:03:32.000 --> 01:03:36.320
have many in this sector. By bringing them together and
1036
01:03:36.360 --> 01:03:40.199
making them work together, we can improve. This is our
1037
01:03:40.199 --> 01:03:50.800
contribution to longevity. Thank you so much, thank you, thank you, thank.
1038
01:03:50.559 --> 01:03:51.440
You so much.
1039
01:03:51.559 --> 01:03:54.360
And next up we have head of Outreach and Marketing
1040
01:03:54.440 --> 01:03:57.960
at the Coalition for Radical Life Extension, a non for
1041
01:03:58.079 --> 01:04:03.599
profit providing education, resources and community for longevity. So please
1042
01:04:03.639 --> 01:04:05.719
give it up for Marianna Deceellis.
1043
01:04:14.280 --> 01:04:17.760
Thank you. I don't have slights, but I do want
1044
01:04:17.800 --> 01:04:22.000
to address your question, Jusse. Right after we introduce ourselves,
1045
01:04:22.079 --> 01:04:25.320
what can we do to advocate for ourselves or what
1046
01:04:25.360 --> 01:04:29.000
can we do? Do you want to said that question, Joset,
1047
01:04:30.840 --> 01:04:34.599
because I'd really want to answer it. Well, I'd like
1048
01:04:34.679 --> 01:04:41.760
to say, Okay, so I do want to answer that
1049
01:04:41.840 --> 01:04:44.719
question that you gave us, because so, yeah, I told
1050
01:04:44.760 --> 01:04:47.239
you about the Coalition for Radical Life Extension. We spoke
1051
01:04:47.239 --> 01:04:51.400
about RADFAST, the Rally for Longevity Rights. The coalition is
1052
01:04:51.440 --> 01:04:55.519
also has launched this year it's global initiative, and this
1053
01:04:55.639 --> 01:04:59.440
global initiative wants to take radfast and beyond and really
1054
01:04:59.440 --> 01:05:03.760
clearly create the platform for and just bring advocacy and
1055
01:05:03.920 --> 01:05:07.599
breage the gap between policy and people and bringing the
1056
01:05:07.639 --> 01:05:12.360
funding for actually age reversal, not just extending human life span.
1057
01:05:12.760 --> 01:05:17.599
And then I really let's keep it personal here because
1058
01:05:17.639 --> 01:05:21.519
we're all people who here. Whether you feel longevity or
1059
01:05:21.559 --> 01:05:24.760
immortality for yourself, you feel something more. And so I
1060
01:05:24.800 --> 01:05:27.039
want to ask you which one of you feels like
1061
01:05:27.320 --> 01:05:30.719
you have an advocate or are advocating for yourself on
1062
01:05:30.760 --> 01:05:32.880
a daily basis?
1063
01:05:32.880 --> 01:05:33.440
Anybody?
1064
01:05:33.559 --> 01:05:39.920
Nobody? Okay, So doesn't that make you feel a little like, oh,
1065
01:05:40.000 --> 01:05:43.320
I don't have anybody advocating for me today? Am I
1066
01:05:43.360 --> 01:05:47.760
advocating for myself today? And so what we're doing, what
1067
01:05:47.800 --> 01:05:50.199
I'm doing with the Coalition and with people Limited, which
1068
01:05:50.199 --> 01:05:52.920
I feel so proud of, is that we've really brought
1069
01:05:52.960 --> 01:05:56.159
together people like Jose has done that here, we've done
1070
01:05:56.199 --> 01:05:58.719
that in this panel. How you've done the car with
1071
01:05:58.760 --> 01:06:01.920
the clinic and Sarah here and how you've done it
1072
01:06:02.000 --> 01:06:05.320
also encoding as well in all of our panel here.
1073
01:06:05.639 --> 01:06:08.599
It really bring people together to remind ourselves and support
1074
01:06:08.639 --> 01:06:12.639
each other and really are pursuit for this more health?
1075
01:06:13.079 --> 01:06:15.000
And so what is worth?
1076
01:06:15.119 --> 01:06:18.400
What it's longevity if you're not going there with anybody?
1077
01:06:18.559 --> 01:06:18.760
Right?
1078
01:06:19.159 --> 01:06:21.199
And what do we do when we feel we don't
1079
01:06:21.199 --> 01:06:24.760
feel as supportive, we feel sad or we get bad biomarkers?
1080
01:06:24.960 --> 01:06:25.760
Who do you tell?
1081
01:06:26.199 --> 01:06:29.760
And what do you do after the event over here tonight?
1082
01:06:30.440 --> 01:06:33.719
And so because you feel this boost, you feel excited,
1083
01:06:33.760 --> 01:06:36.719
you feel seen. I've seen from ten years of working
1084
01:06:36.800 --> 01:06:40.559
with Radfast and almost twenty with People Limited, I've seen
1085
01:06:41.800 --> 01:06:46.519
researchers and scientists come into that room feeling sad because
1086
01:06:46.519 --> 01:06:50.199
they've been unfunded, they don't feel seen because the research
1087
01:06:50.239 --> 01:06:52.760
feels too out there. And then they come in into
1088
01:06:52.840 --> 01:06:55.480
rooms like this and meet people like you, and then
1089
01:06:55.519 --> 01:06:58.440
they feel seen. They find somebody that will find them
1090
01:06:58.480 --> 01:07:01.880
because maybe I know somebody else, But that only happens
1091
01:07:01.880 --> 01:07:05.400
when we get together. And so really we've heard about
1092
01:07:05.440 --> 01:07:08.039
all of the tools that we talked about. However, said
1093
01:07:08.119 --> 01:07:10.480
let's throw all the tools together. And I really quite
1094
01:07:10.519 --> 01:07:14.199
agree with that, and what are those tools if we're
1095
01:07:14.280 --> 01:07:16.719
not you know, what are we doing with these tools?
1096
01:07:16.760 --> 01:07:20.360
And I really feel that community and spirituality really makes
1097
01:07:20.440 --> 01:07:24.039
sense of those tools, because then other than that, you know,
1098
01:07:24.119 --> 01:07:27.239
they're just tools. And so I feel that community really
1099
01:07:27.320 --> 01:07:29.800
puts together not only the purpose, but what we're doing
1100
01:07:29.880 --> 01:07:31.599
with those that sense.
1101
01:07:33.159 --> 01:07:33.840
What can we do?
1102
01:07:34.199 --> 01:07:34.559
I don't know.
1103
01:07:34.679 --> 01:07:36.480
I think we all have an answer to what we
1104
01:07:36.599 --> 01:07:39.639
can do for longevity. I think we all have very
1105
01:07:39.760 --> 01:07:43.000
valid answers. I think on this Cove has a very
1106
01:07:43.079 --> 01:07:46.880
beautiful answer. I think Clara has very beautiful answers. David
1107
01:07:46.960 --> 01:07:50.119
would present that aful beautiful answers. I think we all
1108
01:07:50.199 --> 01:07:52.880
have very valuable answers to what we can do to
1109
01:07:53.000 --> 01:07:56.719
advocate for super longevity, age reversal, and immortality. But I
1110
01:07:56.800 --> 01:07:59.480
can tell you what you can do for me with
1111
01:07:59.719 --> 01:08:02.199
us so that we can help you. I think you
1112
01:08:02.280 --> 01:08:04.599
need to show up like you have here. We need
1113
01:08:04.679 --> 01:08:06.440
to show up to events like this. We need to
1114
01:08:06.480 --> 01:08:08.679
show up to radfast, we need to show up online,
1115
01:08:08.719 --> 01:08:12.239
we need to show up in person, people Limited needs
1116
01:08:12.400 --> 01:08:16.479
twice a week. I've been meeting twice a week for
1117
01:08:16.640 --> 01:08:20.920
eighteen years with people like you that want this, and
1118
01:08:21.359 --> 01:08:24.119
we meet online or in person. We have people that
1119
01:08:24.319 --> 01:08:27.039
have joined us from all over the world, in Africa
1120
01:08:27.279 --> 01:08:30.800
and Asia and all over and these are all people
1121
01:08:30.960 --> 01:08:33.680
like you who are very passionate and really want to
1122
01:08:33.760 --> 01:08:36.600
see this come through. And so I really invite you
1123
01:08:36.760 --> 01:08:39.640
to show up to come and join me. So for
1124
01:08:39.760 --> 01:08:43.439
people Limited that websites people limited ink dot com, for
1125
01:08:43.920 --> 01:08:48.239
Radfast that's ratfest dot com, for the Global Initiative, and
1126
01:08:48.479 --> 01:08:50.880
what we're doing with the coalition, that's our l E
1127
01:08:51.119 --> 01:08:53.800
Coalition dot com. And if you have any questions you
1128
01:08:53.840 --> 01:08:54.920
can come and ask me.
1129
01:08:55.159 --> 01:09:02.479
Thank you, Marianna.
1130
01:09:02.560 --> 01:09:04.680
I think that was a perfect way to sort of
1131
01:09:04.760 --> 01:09:07.640
show that we need a humane aspect when we also
1132
01:09:07.760 --> 01:09:10.680
talk about longevity, and especially when we talk about advocacy,
1133
01:09:11.199 --> 01:09:13.439
because each and one of us are an advocate for
1134
01:09:13.560 --> 01:09:16.800
our own health, there is a sense of sovereignty needed
1135
01:09:16.960 --> 01:09:18.640
and this can then have ripple effects.
1136
01:09:19.079 --> 01:09:20.279
And I think community and.
1137
01:09:20.399 --> 01:09:24.199
Role models are key because we're talking about health. I mean,
1138
01:09:24.279 --> 01:09:26.960
we've been talking about that since, you know, since the
1139
01:09:27.039 --> 01:09:28.880
Stone Age, because we all want to live healthy, but
1140
01:09:28.920 --> 01:09:31.479
I think we need to have a common vision. Why
1141
01:09:31.600 --> 01:09:35.359
do we want to live a long, healthy life? Well,
1142
01:09:35.399 --> 01:09:38.199
presumably not in the way the world looks today. So
1143
01:09:38.279 --> 01:09:40.720
there's so many factors, and I think community is a
1144
01:09:40.800 --> 01:09:44.439
really important one. Infrastructure is another one. But let's hear
1145
01:09:44.560 --> 01:09:48.079
more from a law speaker, Cody Dean, who is an
1146
01:09:48.199 --> 01:09:53.039
entrepreneur and public voice in immortality and longevity culture, especially
1147
01:09:53.119 --> 01:09:55.800
as content creator for the Immortalists.
1148
01:09:55.840 --> 01:09:57.399
So please give it up for Cody.
1149
01:10:01.840 --> 01:10:02.159
Thank you.
1150
01:10:03.199 --> 01:10:05.760
But I also did not come prepared with slides, so
1151
01:10:05.880 --> 01:10:08.520
I apologize for those of you who are visual. You're
1152
01:10:08.560 --> 01:10:10.439
going to have to just power through and listen. Here.
1153
01:10:11.359 --> 01:10:14.000
I want to address the question that Jose posed earlier
1154
01:10:14.119 --> 01:10:16.439
before we started these presentations of how do we move
1155
01:10:16.520 --> 01:10:20.159
this movement forward? And if you really boil it down,
1156
01:10:20.239 --> 01:10:24.279
there's a challenge of supply and demand, which seems simple enough,
1157
01:10:24.399 --> 01:10:26.760
but how do we break that down a little bit more.
1158
01:10:27.279 --> 01:10:30.840
There's a few aspects to this. There's the problem of science,
1159
01:10:30.960 --> 01:10:34.319
which many of you are working on, so you know
1160
01:10:34.399 --> 01:10:38.000
there's that, But why is science why has it not
1161
01:10:38.279 --> 01:10:40.840
achieved a cure to aging and most of these age
1162
01:10:40.880 --> 01:10:44.079
related diseases yet? Is it just because the science isn't there.
1163
01:10:45.039 --> 01:10:47.960
That's a questionable thing. But if we look a little
1164
01:10:48.000 --> 01:10:52.000
bit further back, there's a challenge of funding, which many
1165
01:10:52.079 --> 01:10:55.319
of you have addressed and asked about and talked about.
1166
01:10:55.720 --> 01:11:00.239
And there's also a challenge of potentially outdated policy and
1167
01:11:00.359 --> 01:11:01.640
politics at play here.
1168
01:11:02.399 --> 01:11:03.119
But if you take.
1169
01:11:03.039 --> 01:11:06.279
Another step back, you can see there's an element of
1170
01:11:07.000 --> 01:11:09.960
this is where the demand comes in. It's people who
1171
01:11:10.159 --> 01:11:12.560
want it. You know, we see this crowd here and
1172
01:11:12.920 --> 01:11:17.319
there's a decent number of people watching live and virtually
1173
01:11:17.399 --> 01:11:20.920
around the world, and you know, up to hundreds of
1174
01:11:20.960 --> 01:11:25.199
people who show up to Radfest and Aubrey's event in Dublin.
1175
01:11:25.520 --> 01:11:29.039
You know, there is a community for this, but the
1176
01:11:29.159 --> 01:11:32.920
demand is not to a level where the voice is
1177
01:11:33.000 --> 01:11:37.319
heard loud enough to affect change on a political and
1178
01:11:37.439 --> 01:11:41.079
policy level. And if that were to happen, if enough
1179
01:11:41.119 --> 01:11:43.199
people were to advocate, and this is where the public
1180
01:11:43.359 --> 01:11:45.960
advocacy comes in, we all need to be louder, we
1181
01:11:46.000 --> 01:11:48.800
all need to talk to more people, and in doing so,
1182
01:11:49.399 --> 01:11:53.560
that voice becomes more unified. I've given an analogy before
1183
01:11:53.640 --> 01:11:57.079
of a symphony. How many people have seen the symphony before?
1184
01:11:57.199 --> 01:11:59.279
Or I at least know what that is, so you
1185
01:11:59.479 --> 01:12:02.399
probably at least know what a symphony is when you
1186
01:12:02.520 --> 01:12:05.000
go to a concert, and if you haven't been, just
1187
01:12:05.119 --> 01:12:08.800
imagine you walk into the auditorium similar to this, and
1188
01:12:08.920 --> 01:12:13.000
down in this area is a large orchestra with lots
1189
01:12:13.039 --> 01:12:17.319
of different instruments, and when you get there early enough,
1190
01:12:17.439 --> 01:12:20.399
you see them all warming up. The conductor is off
1191
01:12:20.479 --> 01:12:23.720
the stage and everyone's warming up their instruments, getting tuned.
1192
01:12:24.239 --> 01:12:26.319
And if you look down and you pay attention to
1193
01:12:26.439 --> 01:12:28.720
the flutes, you can kind of hear what the flutes
1194
01:12:28.760 --> 01:12:31.720
are doing. Their scales is very high pitched, very airy,
1195
01:12:32.399 --> 01:12:35.720
and then there's also a cacophony of sound that's secondary
1196
01:12:35.800 --> 01:12:38.680
behind that because you're focused on the flute section. But
1197
01:12:38.840 --> 01:12:41.640
then you shift your attention over to the French horns
1198
01:12:41.880 --> 01:12:45.680
or the trumpets or whichever other instrument, and now that's
1199
01:12:45.720 --> 01:12:48.159
what you hear. You hear them doing their scales, and
1200
01:12:48.199 --> 01:12:50.439
you hear the tone and the tamera of that instrument,
1201
01:12:51.239 --> 01:12:54.039
and then again just a cacophony of sound that the
1202
01:12:54.079 --> 01:12:56.560
flutes have now blended into. And when you don't focus
1203
01:12:56.640 --> 01:13:00.239
on any instrument, it's just a cacophony of sound. Don't
1204
01:13:00.319 --> 01:13:03.920
really hear any particular thing. But when the director comes
1205
01:13:04.000 --> 01:13:06.000
back out and stands at the front and brings his
1206
01:13:06.119 --> 01:13:09.359
hands up, the entire orchestra comes to attention. And when
1207
01:13:09.600 --> 01:13:12.680
the director moves his hands and the song starts, now
1208
01:13:12.800 --> 01:13:15.680
all of a sudden, you hear a unified piece of
1209
01:13:15.880 --> 01:13:19.680
music and it's beautiful. And that's how we need to
1210
01:13:19.800 --> 01:13:22.640
imagine this community and this movement. We need to come
1211
01:13:22.720 --> 01:13:25.640
together and unify that voice so that way it is
1212
01:13:25.840 --> 01:13:29.399
heard as one song, and that will be beautiful and
1213
01:13:29.520 --> 01:13:33.600
it will be heard by the audience, the policy makers,
1214
01:13:33.680 --> 01:13:37.199
the regulators, the governments around the world, and when it's heard,
1215
01:13:38.359 --> 01:13:41.399
they understand that we as a community, as a people,
1216
01:13:41.600 --> 01:13:44.560
not just a longevity of community, but a human community.
1217
01:13:45.159 --> 01:13:48.079
We are the voter base, so they're going to listen
1218
01:13:48.119 --> 01:13:50.680
to us if they want to keep their jobs. So
1219
01:13:51.279 --> 01:13:56.560
when that happens, policy can be adjusted and streamlined in
1220
01:13:56.760 --> 01:14:01.039
order to maintain safety and efficacy, which we we absolutely need.
1221
01:14:01.239 --> 01:14:05.600
Nobody wants fraudsters coming into this space selling snake oil
1222
01:14:05.720 --> 01:14:07.800
and killing a bunch of people because they want to
1223
01:14:07.840 --> 01:14:10.960
make a bunch of money on longevity. We definitely need
1224
01:14:11.119 --> 01:14:15.439
a standard of safety and efficacy, but we can streamline
1225
01:14:15.479 --> 01:14:19.960
regulation so that we were not holding back beneficial therapies
1226
01:14:20.000 --> 01:14:22.520
for ten to fifteen years that could be saving lives
1227
01:14:22.920 --> 01:14:27.399
much sooner because they can prove themselves much faster. So
1228
01:14:27.479 --> 01:14:31.800
when that policy can be streamlined and adjusted, then investors
1229
01:14:32.159 --> 01:14:35.800
see the potential if they see their potential investment having
1230
01:14:35.840 --> 01:14:39.399
a higher profit margin and having that return come back sooner.
1231
01:14:39.920 --> 01:14:42.000
And that's why in a space like what we're doing
1232
01:14:42.079 --> 01:14:46.279
with Neovia, we want to have a proof of concept
1233
01:14:46.439 --> 01:14:49.840
in a city model first and then of course expand
1234
01:14:49.920 --> 01:14:52.319
from there. We'll have a sister city in South America,
1235
01:14:52.840 --> 01:14:55.880
and then maybe eventually one here in Madrid. You know,
1236
01:14:56.760 --> 01:15:00.399
who knows what the future potential holds there. Even just
1237
01:15:00.439 --> 01:15:04.760
starting with one proof of concept, we see that we
1238
01:15:04.880 --> 01:15:09.479
will see that this streamline regulation is going to speed
1239
01:15:09.600 --> 01:15:12.000
up processes. It's going to make more investment come in.
1240
01:15:12.359 --> 01:15:16.079
But parallel to more money coming in and funding your projects,
1241
01:15:16.239 --> 01:15:18.640
there's also going to be a reduction of the cost
1242
01:15:18.720 --> 01:15:21.800
to go through those trials because there won't be as
1243
01:15:21.920 --> 01:15:25.600
much regulatory red tape to go through, and the regulation
1244
01:15:25.760 --> 01:15:31.319
that is there is actually there to promote safety and efficacy.
1245
01:15:31.479 --> 01:15:36.000
We'll have positive regulation and streamline way through it with
1246
01:15:36.359 --> 01:15:39.840
approval processes that happen as trials are happening, and are
1247
01:15:39.920 --> 01:15:43.920
tailored to each therapy and trial that you're trying to do,
1248
01:15:44.119 --> 01:15:47.319
because in this space there are so many different things
1249
01:15:47.439 --> 01:15:52.119
with genetic editing, with a cellular rejuvenation, with stem cells,
1250
01:15:52.479 --> 01:15:56.000
they all require a different way of looking at it
1251
01:15:56.159 --> 01:16:00.439
and proving it safety and efficacy. That one blanket finition
1252
01:16:00.600 --> 01:16:03.319
of that can't be used to cover everything, and that's
1253
01:16:03.319 --> 01:16:07.439
a big challenge we're running into. So as more funding
1254
01:16:07.560 --> 01:16:09.800
rolls in and as the cost of trials come down,
1255
01:16:10.239 --> 01:16:13.560
then we'll finally reach that point where we're five to
1256
01:16:13.720 --> 01:16:16.560
ten years away or three to five years away from
1257
01:16:16.680 --> 01:16:20.760
having a major breakthrough in curing age related diseases and
1258
01:16:21.399 --> 01:16:25.039
ending humans suffering as a result of that is actually
1259
01:16:25.159 --> 01:16:29.520
going to be three to five years away, as where
1260
01:16:29.920 --> 01:16:32.680
we are now. We've heard three to five years, we've
1261
01:16:32.720 --> 01:16:35.439
heard five to ten years, we've heard ten to twenty years.
1262
01:16:36.000 --> 01:16:38.680
For the last forty or fifty years, we need to
1263
01:16:38.720 --> 01:16:41.079
get to a point where three to five years means
1264
01:16:41.119 --> 01:16:44.920
three to five years on the slow end. We think
1265
01:16:44.960 --> 01:16:48.119
we could make things happen much much faster, and that's
1266
01:16:48.159 --> 01:16:51.159
what we plan on doing. But the major goal is
1267
01:16:51.279 --> 01:16:57.119
to open up the funding opportunities, the investment opportunities, into
1268
01:16:57.279 --> 01:17:01.479
your scientific community, into the trial as you are doing again,
1269
01:17:01.600 --> 01:17:04.560
like I said earlier, because selfishly, I want to live
1270
01:17:04.680 --> 01:17:06.600
and I want to be healthy. I don't want to
1271
01:17:06.640 --> 01:17:10.439
grow up older and then die from being sick or
1272
01:17:10.560 --> 01:17:14.159
just getting old. Because we're just dealing with the things
1273
01:17:14.199 --> 01:17:17.279
we're dealing with now. So how do we move this
1274
01:17:17.439 --> 01:17:20.920
movement forward? To break it down to the most simple thing,
1275
01:17:21.640 --> 01:17:26.720
advocate talk to people that demand will through as I
1276
01:17:26.880 --> 01:17:30.199
just discussed, hit all the different points where finally the
1277
01:17:30.319 --> 01:17:32.279
supply will have to be there.
1278
01:17:33.279 --> 01:17:44.079
Thank you, Thank you to all of you great advocates.
1279
01:17:44.359 --> 01:17:47.199
Does anyone have any questions when it comes to advocacy
1280
01:17:47.239 --> 01:17:50.079
because this is actually a topic that relates to each
1281
01:17:50.159 --> 01:17:53.359
and every one of us, so you know, no questions
1282
01:17:53.439 --> 01:17:54.239
are too small.
1283
01:17:57.800 --> 01:18:00.119
Oh you know, could we just have a short does
1284
01:18:00.279 --> 01:18:01.840
mad what the question was in English?
1285
01:18:02.439 --> 01:18:04.279
So maybe the audience not I one in Spanish?
1286
01:18:07.479 --> 01:18:12.079
I think I think you were asking about that all
1287
01:18:12.159 --> 01:18:13.680
tel question on whether.
1288
01:18:13.720 --> 01:18:14.600
You know what happens?
1289
01:18:15.439 --> 01:18:18.319
You know, do you distribute money first to guns or
1290
01:18:18.399 --> 01:18:21.840
do they go to fiting? And how do we and
1291
01:18:22.359 --> 01:18:24.319
what are kind of alliances are we going to make
1292
01:18:24.319 --> 01:18:27.039
sure to make so that we know that that money's
1293
01:18:27.079 --> 01:18:27.760
been distributed?
1294
01:18:27.840 --> 01:18:28.000
Right?
1295
01:18:29.000 --> 01:18:32.119
If I can take that question first, I will say,
1296
01:18:32.840 --> 01:18:35.680
until we solve aging, there's always going to be worse.
1297
01:18:36.520 --> 01:18:38.800
I mean, I think there's always going to be death.
1298
01:18:38.960 --> 01:18:42.039
But once we cure aging, there's going to be a
1299
01:18:42.119 --> 01:18:44.800
huge culture shift. I mean, we're looking at the biggest
1300
01:18:44.920 --> 01:18:50.439
paradigm shift we've ever seen has humanity. And unfortunately people
1301
01:18:50.560 --> 01:18:53.359
see death like part of a circle. That's not how
1302
01:18:53.439 --> 01:18:56.640
I feel, that's not what I see. I feel differently.
1303
01:18:56.760 --> 01:18:59.880
But once we cure death and the diseases of aging,
1304
01:19:00.119 --> 01:19:03.239
the whole paradigm that we've known so far as humans
1305
01:19:03.279 --> 01:19:05.920
and culture are completely going to change. So the question
1306
01:19:06.039 --> 01:19:09.039
we posed so far and the way we've treated each
1307
01:19:09.079 --> 01:19:12.000
other so far are going to change. Because if you're
1308
01:19:12.079 --> 01:19:14.960
not just getting rid of ten years worth of living
1309
01:19:15.039 --> 01:19:17.720
of a human, you're getting rid of five hundred years.
1310
01:19:18.319 --> 01:19:23.439
So yeah, hopefully we're expanding our consciousness and seeing other
1311
01:19:23.520 --> 01:19:26.520
things worthwhile than what we've seen in the last decade
1312
01:19:26.560 --> 01:19:28.800
of man hurting man.
1313
01:19:28.960 --> 01:19:32.960
Yes, actually Spanish scientists who got the Nobel Price and
1314
01:19:33.039 --> 01:19:37.199
Teago Ramonica help so he gave classes here. By the way,
1315
01:19:37.479 --> 01:19:41.880
Santiago Ramonica Hall lectured here our first Nobel prize in
1316
01:19:42.960 --> 01:19:46.199
nineteen o six or something like that.
1317
01:19:46.520 --> 01:19:47.960
I was not born at the time.
1318
01:19:48.399 --> 01:19:49.000
There we have one.
1319
01:19:49.640 --> 01:19:52.600
I think you have to make a ratio between how
1320
01:19:52.720 --> 01:19:57.680
much money is spent in health and in weapons per
1321
01:19:57.840 --> 01:20:02.640
year for Washington and the radio property is going to
1322
01:20:02.760 --> 01:20:07.079
be two minutes of defense expenditure in one year is
1323
01:20:07.159 --> 01:20:08.439
less than what we're spending here.
1324
01:20:08.960 --> 01:20:11.439
Yeah, we need the politicians at the table so we
1325
01:20:11.520 --> 01:20:12.800
can ask that question.
1326
01:20:14.159 --> 01:20:14.680
Marianna.
1327
01:20:14.920 --> 01:20:18.479
Since you are organized in the march, they're running in Washington,
1328
01:20:18.600 --> 01:20:21.399
d see, what are you going to tell President Trump.
1329
01:20:24.199 --> 01:20:24.800
I'm not going to.
1330
01:20:24.800 --> 01:20:28.640
Answer that, but I will answer is that the march
1331
01:20:28.840 --> 01:20:33.479
is focusing on longevity rights because we don't want this
1332
01:20:33.680 --> 01:20:35.760
to be something that can be used against us.
1333
01:20:35.840 --> 01:20:38.159
We spoke about safety and security before.
1334
01:20:38.640 --> 01:20:40.720
So one of the biggest focus of the Coalition and
1335
01:20:40.800 --> 01:20:43.640
the March is going to be to really make this
1336
01:20:44.000 --> 01:20:47.359
about everybody and not just about longevity and immortality, but
1337
01:20:47.520 --> 01:20:50.119
really about all of us being able to get access
1338
01:20:50.199 --> 01:20:52.479
to all of this medicine. And we feel that that
1339
01:20:52.600 --> 01:20:55.039
it will be the first door to open and then
1340
01:20:55.079 --> 01:20:57.039
all of this will be because I also have the
1341
01:20:57.159 --> 01:21:00.479
same concerns as we do. So I'm glad you're putting
1342
01:21:00.520 --> 01:21:01.000
that out there.
1343
01:21:02.840 --> 01:21:03.680
Any more questions.
1344
01:21:04.920 --> 01:21:07.079
I mean, all of you are are advocates, So if
1345
01:21:07.119 --> 01:21:10.119
we would sort of summarize and maybe hand the tool
1346
01:21:10.199 --> 01:21:11.800
of advocacy to people.
1347
01:21:11.680 --> 01:21:14.720
Here, if you could each share, you know, your own sort.
1348
01:21:14.520 --> 01:21:18.439
Of nugget on advocacy. How do how do we create
1349
01:21:18.479 --> 01:21:22.760
a narrative around longevity? I mean some say immortality, some
1350
01:21:22.960 --> 01:21:27.239
say radical life extensions, some say hell, some say living forever.
1351
01:21:27.680 --> 01:21:30.880
You know, if we're going to unify this advocacy, if
1352
01:21:30.960 --> 01:21:31.279
each and.
1353
01:21:31.319 --> 01:21:34.199
Every one of you know, did you have like a tagline,
1354
01:21:34.640 --> 01:21:36.920
and then we can get some inspiration when it comes
1355
01:21:37.000 --> 01:21:41.279
to longevity or eternal living, flourishing.
1356
01:21:40.960 --> 01:21:42.640
Joy, spam, whatever it might be.
1357
01:21:44.119 --> 01:21:44.319
Yeah.
1358
01:21:44.520 --> 01:21:46.840
Well, to finish, I'm going to be a little bit
1359
01:21:46.960 --> 01:21:47.640
more general.
1360
01:21:47.960 --> 01:21:53.000
So my main advice I cannot avoid to give advices
1361
01:21:53.039 --> 01:21:56.520
because I'm mother for two daughters and one son, and
1362
01:21:56.680 --> 01:21:58.640
I used to do advices.
1363
01:21:59.319 --> 01:22:03.600
So my many advice is to support science and to
1364
01:22:03.720 --> 01:22:05.560
pay attention to scientists.
1365
01:22:05.640 --> 01:22:10.039
It's very important to have critical thinking talking about longevity,
1366
01:22:10.199 --> 01:22:13.800
about health, about many other things. We pay attention to
1367
01:22:14.720 --> 01:22:21.119
people that really don't give advices support it by science data.
1368
01:22:21.319 --> 01:22:24.880
So this is very important to develop the critical thinking.
1369
01:22:25.399 --> 01:22:28.800
So this is one of my first advices. The other
1370
01:22:28.920 --> 01:22:33.359
one is as a citizen, we can really support companies
1371
01:22:33.600 --> 01:22:36.960
that support science instead many other things like.
1372
01:22:37.000 --> 01:22:37.880
Weapons or whatever.
1373
01:22:38.479 --> 01:22:42.279
So we should develop also our critical thinking to see
1374
01:22:42.880 --> 01:22:48.600
which companies we like and we don't, So this is important.
1375
01:22:48.640 --> 01:22:52.479
And for the companies, I will advise you to use
1376
01:22:52.640 --> 01:22:57.960
your responsibility to support science for example through a patinal,
1377
01:22:58.000 --> 01:23:01.840
a TENTFIA and as a citizens also I mean something
1378
01:23:01.920 --> 01:23:04.920
that we want to be to be.
1379
01:23:05.039 --> 01:23:10.079
Happy, to be healthy and happy. And one that of
1380
01:23:10.199 --> 01:23:13.439
the things that make us very happy is the generosity.
1381
01:23:13.960 --> 01:23:16.800
So when you find a course, you find a purpose
1382
01:23:16.880 --> 01:23:21.079
in your life and you really support it by a
1383
01:23:21.159 --> 01:23:24.239
donation or by a collaboration with it. So we are
1384
01:23:24.399 --> 01:23:29.239
here to have you. You are happy and finally you
1385
01:23:29.399 --> 01:23:32.439
are you are better in life.
1386
01:23:32.640 --> 01:23:36.720
So please I hope many of you find a paternal
1387
01:23:36.760 --> 01:23:41.199
athenia a good way to really put your donation or
1388
01:23:41.279 --> 01:23:44.520
do your collaboration to support science that finally is going
1389
01:23:44.600 --> 01:23:45.359
to impact in.
1390
01:23:45.560 --> 01:23:46.600
All our lives.
1391
01:23:47.079 --> 01:23:50.479
And also you have the possibility to reduce the taxes
1392
01:23:50.560 --> 01:23:52.439
because a parentalth Infia.
1393
01:23:52.600 --> 01:23:57.960
Got the position of Tilda public. So please you are
1394
01:23:58.000 --> 01:24:01.560
welcome to come to visitors. I think, thank you.
1395
01:24:02.039 --> 01:24:02.600
I just want to.
1396
01:24:02.600 --> 01:24:05.840
Support her idea. It's the law of life is really
1397
01:24:05.880 --> 01:24:09.079
what defines the community. We love life so deeply, we
1398
01:24:09.279 --> 01:24:11.760
really want to extend it. We find it extremely unfair,
1399
01:24:12.520 --> 01:24:13.479
and I think.
1400
01:24:13.319 --> 01:24:16.079
It's not hard to drive this feeling into everyone.
1401
01:24:16.600 --> 01:24:19.399
We really I think that the problem is most people have.
1402
01:24:19.479 --> 01:24:22.880
Not heard that this is even possible. Honestly, most people
1403
01:24:22.960 --> 01:24:25.760
that I talk about it with and just regular people,
1404
01:24:25.800 --> 01:24:30.239
most people are supportive of life extension. And I think
1405
01:24:30.279 --> 01:24:32.640
it's more of a marketing and a media effort. And
1406
01:24:32.720 --> 01:24:36.960
as soon as we all everybody realizes life is so valuable,
1407
01:24:37.039 --> 01:24:39.359
so important that who wants to kill each other to
1408
01:24:39.439 --> 01:24:43.720
have arguments, to have fights to discuss silly political part
1409
01:24:43.760 --> 01:24:45.680
also the trend of the right and the left, and
1410
01:24:46.680 --> 01:24:48.600
so we're so sick of it that we have to
1411
01:24:48.680 --> 01:24:52.880
move past this period. It's really annoying and frustrating that
1412
01:24:53.439 --> 01:24:56.399
the debates are not more more enlivening.
1413
01:24:57.720 --> 01:25:00.319
There needs to be a mirroring the weapon here in
1414
01:25:00.399 --> 01:25:02.880
health here, and there's a mirror because everybody wants initially
1415
01:25:02.960 --> 01:25:05.479
what you're saying, But we're living in a world where fear.
1416
01:25:05.279 --> 01:25:07.800
And scarcity is but nobody knows what transhuman is.
1417
01:25:07.840 --> 01:25:08.159
Amiss.
1418
01:25:08.239 --> 01:25:08.439
Yeah.
1419
01:25:11.000 --> 01:25:13.399
On a similar tone, I don't tend to speak to
1420
01:25:13.479 --> 01:25:17.960
my patients about immortality, but I always try to ask
1421
01:25:18.039 --> 01:25:21.319
them like, do you want to die tomorrow? They usually
1422
01:25:21.359 --> 01:25:24.840
say no, and then it comes like what makes you
1423
01:25:24.960 --> 01:25:28.279
think that you will want to die someday if you're
1424
01:25:28.279 --> 01:25:31.560
a great health. So I think that for the general
1425
01:25:31.640 --> 01:25:35.600
society talking about infinity immortality, it's just like concepts. They
1426
01:25:35.640 --> 01:25:37.960
can really grass no exactly, but when they put it
1427
01:25:38.039 --> 01:25:41.640
into the perspective of today, no one wants to die tomorrow,
1428
01:25:42.079 --> 01:25:44.199
and eventually that means that you don't want to die
1429
01:25:44.239 --> 01:25:46.800
at some point if you're in great health. And as
1430
01:25:46.800 --> 01:25:49.119
we're talking about advocacy and I don't want to extend
1431
01:25:49.119 --> 01:25:51.319
because I know it's too long, I would love to
1432
01:25:51.359 --> 01:25:54.279
make a small remark, especially going back to the science part,
1433
01:25:54.800 --> 01:25:58.680
that we need to do more research on female longevity definitely.
1434
01:25:59.039 --> 01:26:05.960
So it's if longevity has little funding, female longevity as
1435
01:26:06.079 --> 01:26:10.840
lost to none and women age differently than men exactly.
1436
01:26:10.880 --> 01:26:12.119
So as an.
1437
01:26:12.039 --> 01:26:15.119
Advocate and having a microphone in my hand. This fun
1438
01:26:15.279 --> 01:26:17.520
female research, female angevity research.
1439
01:26:19.560 --> 01:26:23.199
And to add to that, there is something in the making,
1440
01:26:23.560 --> 01:26:26.319
the launch of Superwoman, which is going to be dedicated
1441
01:26:26.439 --> 01:26:29.159
just to that. So I'm really getting all the women
1442
01:26:29.239 --> 01:26:32.239
I can find to get together and make that happen.
1443
01:26:32.439 --> 01:26:36.039
As I said before, we need to keep pushting, developing
1444
01:26:36.359 --> 01:26:40.640
and fostering public and private collaboration because we need a
1445
01:26:40.680 --> 01:26:43.760
better system that prevents, not just cares what prevents.
1446
01:26:45.000 --> 01:26:45.319
Thank you.
1447
01:26:46.119 --> 01:26:50.000
I think we cannot be afraid of spirituality and the
1448
01:26:50.079 --> 01:26:52.279
divinity of the body, and we need to remind each
1449
01:26:52.319 --> 01:26:54.920
other of that. I think that when people think of
1450
01:26:55.039 --> 01:26:57.279
cure and aging, they think you're trying to play God.
1451
01:26:57.479 --> 01:26:59.720
And I don't see anything wrong with that statement.
1452
01:26:59.840 --> 01:27:02.600
I think we are and I think we all here.
1453
01:27:03.039 --> 01:27:05.119
Of something in common, and it's that we do all
1454
01:27:05.239 --> 01:27:08.800
feel the value of human life, of our bodies and
1455
01:27:08.960 --> 01:27:13.119
some other people's bodies that we've lost, and so for
1456
01:27:13.640 --> 01:27:16.000
all of us to not forget why we're doing this,
1457
01:27:16.159 --> 01:27:18.720
and it really is the celebration of the divinity of
1458
01:27:18.800 --> 01:27:19.199
the body.
1459
01:27:20.000 --> 01:27:20.359
Thank you.
1460
01:27:21.960 --> 01:27:25.319
To go back to the original question of immortality versus
1461
01:27:25.520 --> 01:27:28.520
radical life, extension versus longevity, and how do we combine
1462
01:27:28.600 --> 01:27:32.159
all of that. To me, the common denominator is do
1463
01:27:32.359 --> 01:27:36.439
you want to live healthier, longer period. If the answer
1464
01:27:36.520 --> 01:27:38.920
is yes, you're a part of this community. After that,
1465
01:27:39.199 --> 01:27:41.960
it's a personal choice on the individual level of how
1466
01:27:42.079 --> 01:27:42.960
much longer.
1467
01:27:42.760 --> 01:27:46.279
Do you want? And I really think, you know, I
1468
01:27:46.399 --> 01:27:48.600
think that the purpose is also we need to find
1469
01:27:48.680 --> 01:27:51.399
purpose and meaning in our own lives and in sort
1470
01:27:51.399 --> 01:27:53.920
of the life in general. And I think when we
1471
01:27:54.039 --> 01:27:57.680
start to navigate, whether it's spirituality, divinity, I mean, these
1472
01:27:57.880 --> 01:28:00.600
concepts are getting much more into the life now. A
1473
01:28:00.640 --> 01:28:02.560
few years ago when you spoke about this, it was
1474
01:28:02.600 --> 01:28:04.720
a bit woo woo, but this is actually, you know,
1475
01:28:05.119 --> 01:28:08.000
self evolvement. We're here for a great adventure called life.
1476
01:28:08.079 --> 01:28:10.720
Of course, we want to live, enjoy and happiness, but
1477
01:28:10.840 --> 01:28:13.039
we also need to be sovereign and start to maybe
1478
01:28:13.119 --> 01:28:13.640
demand that.
1479
01:28:13.800 --> 01:28:15.880
And it comes from you know, the people.
1480
01:28:16.359 --> 01:28:20.960
And longevity is an amazing, amazing, you know occurrence that
1481
01:28:21.079 --> 01:28:25.319
it's happened now because advocacy has never been stronger, because
1482
01:28:25.359 --> 01:28:27.920
people are voicing up. The science is there, and I
1483
01:28:28.000 --> 01:28:29.760
think it's going to you know, accelerate more and more
1484
01:28:30.000 --> 01:28:31.000
thanks to people like you.
1485
01:28:31.199 --> 01:28:33.319
So round of applause for all of our advocates.
1486
01:28:33.359 --> 01:28:34.319
A leader is thank you.
1487
01:28:38.960 --> 01:28:39.319
Thank you.
1488
01:28:43.720 --> 01:28:49.239
So with that, ladies and gentlemen and advocates of longevity
1489
01:28:49.279 --> 01:28:54.159
and pioneers, our final keynote speaker is truly a pioneer herself,
1490
01:28:54.279 --> 01:28:57.560
both as a leader how she came into the longevity space,
1491
01:28:57.880 --> 01:29:00.800
which many times happen because you have a person issue
1492
01:29:00.880 --> 01:29:03.359
with which she had with her son. But she's a
1493
01:29:03.439 --> 01:29:06.680
pioneer within gene therapy and one of the boldest voices
1494
01:29:06.760 --> 01:29:09.560
in the field as well, because she allows also to
1495
01:29:09.680 --> 01:29:10.600
be provocative.
1496
01:29:10.960 --> 01:29:12.720
Not Lisa's gene therapy.
1497
01:29:12.720 --> 01:29:15.520
As we know, is not accessible, but she's really traveling
1498
01:29:15.880 --> 01:29:19.600
the globe around to really make this accessible in certain
1499
01:29:19.640 --> 01:29:22.640
parts of the world. She's the founder and CEO of Bioviva,
1500
01:29:23.000 --> 01:29:27.319
a driven humanitarian entrepreneur and a leading voice for genetic cures,
1501
01:29:27.600 --> 01:29:32.159
and she's championing gene therapies as a path to human rejuvenation.
1502
01:29:32.479 --> 01:29:34.760
And here we can talk about human trials because she
1503
01:29:35.439 --> 01:29:38.399
is doing this on herself. Please give it up if
1504
01:29:38.439 --> 01:29:41.359
she's with us, Liz perish.
1505
01:29:42.640 --> 01:29:49.479
Hopefully, Okay, fantastic.
1506
01:29:49.680 --> 01:29:52.279
It's nice to be here everyone, and so let me
1507
01:29:52.359 --> 01:29:53.520
get my slides ready.
1508
01:29:54.279 --> 01:29:59.359
I have the Hi Jose how are you awesome?
1509
01:30:00.000 --> 01:30:03.159
I just okay, great, I can share my slides. It
1510
01:30:03.239 --> 01:30:06.920
looks like and so we'll get on that. I hope
1511
01:30:06.960 --> 01:30:09.560
everyone's enjoying the conference. It looks like you guys had
1512
01:30:09.600 --> 01:30:15.600
a terrific March two for the Death of Death, so
1513
01:30:15.960 --> 01:30:20.840
fantastic and congratulations on that. Okay, fantastic. So we're going
1514
01:30:20.920 --> 01:30:23.720
to talk about the evolution of gene therapy, where we've
1515
01:30:23.800 --> 01:30:24.119
been and.
1516
01:30:24.159 --> 01:30:25.079
Where we are going.
1517
01:30:25.760 --> 01:30:28.000
As you know, Bioviva has had a little bit of
1518
01:30:28.079 --> 01:30:34.119
a rocky road this year because of what's called hands
1519
01:30:34.239 --> 01:30:35.079
off research.
1520
01:30:36.479 --> 01:30:36.640
Hi.
1521
01:30:38.399 --> 01:30:42.479
I can see everyone in the audience. Hey, everyone, whoo,
1522
01:30:43.279 --> 01:30:45.760
shake it up, get your body moving. I know it's
1523
01:30:46.119 --> 01:30:48.479
evening for you, but it's early in the morning for me.
1524
01:30:49.159 --> 01:30:55.880
You guys all look fantastic, So let me proceed in
1525
01:30:56.039 --> 01:30:58.399
hands off research. What we do is we pay a
1526
01:30:58.560 --> 01:31:02.239
university to do research, and then sometimes there are things
1527
01:31:02.319 --> 01:31:07.239
called detractors, and sometimes there are things called missteps in science.
1528
01:31:07.720 --> 01:31:10.119
And right now we have a paper that's under review
1529
01:31:10.319 --> 01:31:11.039
for just that.
1530
01:31:11.479 --> 01:31:13.760
And I imagine the infernos.
1531
01:31:13.199 --> 01:31:17.000
Of hell are going to be burning bright in the
1532
01:31:17.119 --> 01:31:20.399
near future for one side or the other. So we
1533
01:31:20.520 --> 01:31:23.960
can't talk too much about that today because that's under investigation.
1534
01:31:24.800 --> 01:31:28.479
But I'll let you know that our company is dedicated
1535
01:31:28.600 --> 01:31:32.960
to science and science working for humans. We are translational
1536
01:31:33.079 --> 01:31:35.960
engine and that's what we're going to get into today.
1537
01:31:36.399 --> 01:31:39.960
If science can't translate to humans, then we are all
1538
01:31:40.159 --> 01:31:42.960
going to die. And I'm going to show you how
1539
01:31:43.119 --> 01:31:46.079
we have proven that science has already translated and that
1540
01:31:46.159 --> 01:31:47.119
we can build upon it.
1541
01:31:47.840 --> 01:31:49.720
But if we are detracted from.
1542
01:31:49.840 --> 01:31:53.640
And science is blocked, that would be the responsibility of
1543
01:31:53.680 --> 01:31:55.119
the murder of millions of people.
1544
01:31:55.520 --> 01:31:58.159
And so we also have to watch that side of
1545
01:31:58.279 --> 01:31:58.760
the aisle.
1546
01:32:00.159 --> 01:32:04.760
Let's get into an exciting presentation in which I think
1547
01:32:04.840 --> 01:32:05.560
you can all.
1548
01:32:05.520 --> 01:32:07.399
Agree we need the cure aging.
1549
01:32:08.680 --> 01:32:11.640
So we're going to go back really quick historically into
1550
01:32:11.760 --> 01:32:13.439
the death records of humans.
1551
01:32:13.560 --> 01:32:15.600
And this is because I want to show you that
1552
01:32:15.760 --> 01:32:17.520
science is already working.
1553
01:32:17.800 --> 01:32:24.039
We have basically elucidated many different scientific advances to extend
1554
01:32:24.159 --> 01:32:25.479
human lifespan.
1555
01:32:25.399 --> 01:32:27.359
And these records are evidence of that.
1556
01:32:27.960 --> 01:32:32.000
So in sixteen sixty five, we vastly died of infectious disease,
1557
01:32:32.640 --> 01:32:35.439
and because we took it so seriously, by the year
1558
01:32:35.600 --> 01:32:39.039
of nineteen hundred, we got that infectious disease rate down
1559
01:32:39.119 --> 01:32:41.920
to almost fifty percent of the population. And that was
1560
01:32:42.000 --> 01:32:46.359
because we used science, a technology that's rigorous that tests
1561
01:32:46.479 --> 01:32:51.359
whether or not something will work to circumvent maybe in
1562
01:32:51.479 --> 01:32:55.439
this case, a death outcome. And this is fantastic because
1563
01:32:55.520 --> 01:32:58.479
this made it so that we could live longer and healthier.
1564
01:32:59.000 --> 01:33:03.680
But if you notice graph, we start to see the.
1565
01:33:03.800 --> 01:33:07.960
Expansion of diseases that we didn't have on the original graph,
1566
01:33:08.199 --> 01:33:10.119
and that is because we started to.
1567
01:33:11.039 --> 01:33:13.880
Name aging associate diseases.
1568
01:33:14.239 --> 01:33:17.680
So by the year twenty ten, only three percent of
1569
01:33:17.760 --> 01:33:20.359
the population is dying of infectious disease.
1570
01:33:20.720 --> 01:33:21.760
And this is science.
1571
01:33:21.920 --> 01:33:26.199
This is science showing that already it's working on life expansion.
1572
01:33:26.319 --> 01:33:30.920
So longevity science started way back, probably around the eighteen
1573
01:33:31.039 --> 01:33:34.920
hundreds and has advanced beautifully since then. So if people
1574
01:33:35.039 --> 01:33:39.720
say that it is science fiction to extend lifespan, actually
1575
01:33:40.199 --> 01:33:43.119
most of the population has already benefited from that.
1576
01:33:44.560 --> 01:33:45.680
So when we look at.
1577
01:33:45.600 --> 01:33:48.840
Old medicine, we looked at symptom management, and we still
1578
01:33:48.920 --> 01:33:52.079
have a lot of this, mostly in the healthcare system,
1579
01:33:52.600 --> 01:33:55.720
not so much in medical tourism. But we do what's
1580
01:33:55.760 --> 01:34:00.399
called symptom management, and we use tools and we look
1581
01:34:00.439 --> 01:34:02.960
at herbal remedies and natural things that we can do,
1582
01:34:03.520 --> 01:34:06.800
and this is really still where diet and exercise lies.
1583
01:34:07.039 --> 01:34:09.680
It's powerful technology and you can see that it got
1584
01:34:09.800 --> 01:34:13.239
us a long ways. Then as we advanced, we worked
1585
01:34:13.279 --> 01:34:17.119
into diagnostics. How did we actually diagnose something before it
1586
01:34:17.319 --> 01:34:20.560
happened instead of waiting for it to happen, And this
1587
01:34:20.920 --> 01:34:24.239
really opened the realm of regeederative medicine to step in.
1588
01:34:24.479 --> 01:34:28.319
And that is really the third stage, which is using
1589
01:34:28.399 --> 01:34:32.239
regenerative medicine to create a cell that stays in homeostasis,
1590
01:34:32.880 --> 01:34:37.399
that ages as slowly as possible, or maybe even reversus aging.
1591
01:34:37.920 --> 01:34:39.680
So I'm going to talk about.
1592
01:34:39.600 --> 01:34:43.479
Our modalities of how we work, and we work at
1593
01:34:43.560 --> 01:34:48.920
Bioviva in genetics and in gene therapy. So our mission
1594
01:34:49.159 --> 01:34:52.680
is to find gene therapies that will modulate the aging
1595
01:34:52.800 --> 01:34:56.560
process and keep the body in homeostasis. How I became
1596
01:34:56.680 --> 01:35:00.720
a GMO and why I think you will too was
1597
01:35:00.800 --> 01:35:03.760
a long journey that I've had over twelve years in
1598
01:35:03.840 --> 01:35:07.880
regenerative medicine in ten years with the company Bioviva, and
1599
01:35:08.399 --> 01:35:11.680
the evidence that we've shown that probably actually working with
1600
01:35:11.920 --> 01:35:14.800
genetic therapeutics is the best way to move forward for
1601
01:35:14.920 --> 01:35:18.199
most of the population because then you can set a
1602
01:35:18.319 --> 01:35:22.359
lot of your biological aging therapies and forget them at
1603
01:35:22.439 --> 01:35:24.479
least for ten to fifteen years.
1604
01:35:24.680 --> 01:35:26.880
And that's an unimaginably powerful tool.
1605
01:35:27.079 --> 01:35:30.359
We will probably need other tools alongside this technology, and
1606
01:35:30.439 --> 01:35:33.760
we'll talk about those as we go. So why I
1607
01:35:33.920 --> 01:35:37.359
became a GMO is I was working regenerative medicine for
1608
01:35:37.439 --> 01:35:40.239
two years and my son was diagnosed with type one
1609
01:35:40.319 --> 01:35:42.319
diabetes in twenty thirteen.
1610
01:35:43.159 --> 01:35:45.640
So after working in the regenerative medicine.
1611
01:35:45.239 --> 01:35:48.039
Space, I thought that once I ended up in the
1612
01:35:48.079 --> 01:35:52.279
hospital or a loved one did, that this regenerative medicine
1613
01:35:52.319 --> 01:35:55.399
technology would be available for us, that we would not
1614
01:35:55.680 --> 01:35:58.560
be fighting diseases with palliative care.
1615
01:35:59.199 --> 01:36:00.680
But in fact I was wrong.
1616
01:36:01.000 --> 01:36:04.880
This type of technology was not translating quickly, not quickly
1617
01:36:05.039 --> 01:36:07.720
enough for most patients on the hills of Going to
1618
01:36:07.840 --> 01:36:11.520
a SENSE conference later that year to meet the professor
1619
01:36:11.560 --> 01:36:14.680
of genetics at Harvard, George Church, which eventually joined the
1620
01:36:14.760 --> 01:36:17.960
company as a founder, I found out that by treating
1621
01:36:18.039 --> 01:36:23.680
biological aging and treating the genetic basis of biological aging,
1622
01:36:23.760 --> 01:36:26.760
we could actually expedite cures for these kids. And so
1623
01:36:27.159 --> 01:36:30.199
my company, Bioviva, every gene we have chosen since then
1624
01:36:30.279 --> 01:36:33.239
will actually treat both ends of the spectrum, so the
1625
01:36:33.399 --> 01:36:37.760
aging population and the young population, basically taking care of
1626
01:36:37.840 --> 01:36:39.840
the critical care for the most.
1627
01:36:39.760 --> 01:36:41.960
Vulnerable populations on the planet.
1628
01:36:43.199 --> 01:36:46.680
And why do we need to do that because both
1629
01:36:47.439 --> 01:36:52.000
vulnerable ends of the population drain a lot in resources.
1630
01:36:52.159 --> 01:36:53.399
So when you're young, you.
1631
01:36:53.439 --> 01:36:56.439
Don't have a job, makes sense, society pays for you
1632
01:36:56.720 --> 01:36:59.760
to grow up. Then you're in your earning stages, in
1633
01:36:59.800 --> 01:37:03.079
wh you are profitable in the sense that you're above
1634
01:37:03.199 --> 01:37:07.000
what it costs to live, and then as you age, unfortunately,
1635
01:37:07.119 --> 01:37:10.159
you fall back below this line. And this is really
1636
01:37:10.279 --> 01:37:14.279
critical because many people who are in this age group
1637
01:37:14.319 --> 01:37:17.159
of around fifty five still have dreams.
1638
01:37:17.239 --> 01:37:20.199
There are still things they want to do. But these
1639
01:37:20.439 --> 01:37:22.800
estimates in earning versus.
1640
01:37:22.640 --> 01:37:25.279
Eating would tell us that your dreams are over and
1641
01:37:25.439 --> 01:37:29.800
you better breaks for the future of really high costs
1642
01:37:29.920 --> 01:37:30.600
and healthcare.
1643
01:37:31.479 --> 01:37:34.159
We want to change that. So what does that look like.
1644
01:37:34.319 --> 01:37:37.600
Let's go back to sixteen sixty five. Infectious disease. You're
1645
01:37:37.640 --> 01:37:40.479
going along, you get an infectious disease, you die fast.
1646
01:37:41.840 --> 01:37:44.399
The middle graph is what happens today. That is the
1647
01:37:44.479 --> 01:37:48.600
death curve, the slow death curve, and decline into in
1648
01:37:48.760 --> 01:37:52.119
stage diseases, and what happens is you get a symptom
1649
01:37:52.640 --> 01:37:56.000
and then we try to recover you with today's medicine,
1650
01:37:56.079 --> 01:37:58.960
but generally we put you back on the death curve
1651
01:37:59.560 --> 01:38:03.039
and your health continues to decline, but you continue to
1652
01:38:03.239 --> 01:38:06.319
consume these drugs that at least keep you alive. The
1653
01:38:06.439 --> 01:38:09.479
graph on the right we call tomorrow's medicine, but it's
1654
01:38:09.520 --> 01:38:13.880
already started about ten years ago when we started. And
1655
01:38:14.439 --> 01:38:19.079
this is what happens when we look at genetics, the
1656
01:38:19.199 --> 01:38:23.520
ability to potentially restore the body to a healthy state.
1657
01:38:23.680 --> 01:38:26.600
I was just at Harvard with David Sinclair a couple
1658
01:38:26.600 --> 01:38:30.039
of days ago, and he has amazing research also going
1659
01:38:30.119 --> 01:38:32.840
on in gene therapy. Some of the things that we
1660
01:38:33.119 --> 01:38:37.399
do it bio viva as well, and incorporating all of
1661
01:38:37.479 --> 01:38:42.159
these things looks incredibly promising to maybe deliver on this
1662
01:38:42.359 --> 01:38:43.279
graph that I'm showing you.
1663
01:38:44.000 --> 01:38:45.960
So what is gene therapy.
1664
01:38:46.279 --> 01:38:49.960
With gene therapy today, we use AAV It's a deno
1665
01:38:50.039 --> 01:38:53.640
associate virus. It is what used to be a virus
1666
01:38:53.720 --> 01:38:56.319
and it's now attenuated and called a vector.
1667
01:38:56.439 --> 01:38:58.079
It can no longer get you sick.
1668
01:38:58.800 --> 01:39:02.439
But what's really great about these vectors is nature has
1669
01:39:02.520 --> 01:39:07.560
designed them eloquently to deliver to your cell's genetic material
1670
01:39:07.680 --> 01:39:11.279
to the nucleus for long term expression. So we can
1671
01:39:11.359 --> 01:39:14.279
take something that used to get you sick and turn
1672
01:39:14.359 --> 01:39:19.840
it into something that delivers healthy genes that are required
1673
01:39:20.000 --> 01:39:24.840
for sustained gene expression of youthful bodies. And basically we
1674
01:39:25.000 --> 01:39:29.479
call that a regain of function and a restoration to
1675
01:39:30.520 --> 01:39:34.640
healthy and therapeutic benefit of these genes. So what you'll
1676
01:39:34.680 --> 01:39:38.720
see is it delivers that gene sequence into the nucleus
1677
01:39:38.760 --> 01:39:41.720
of the cell and then it's transcribed and it creates
1678
01:39:41.760 --> 01:39:45.680
a protein. And those proteins are what make you up.
1679
01:39:45.880 --> 01:39:50.039
So those proteins are very important for the health of
1680
01:39:50.159 --> 01:39:57.199
your body. They're given by IV, intramuscular injection, intranasal injection,
1681
01:39:58.119 --> 01:40:03.279
organ delivery directly, and there are some gene therapies that
1682
01:40:03.319 --> 01:40:06.359
are given topical for children with rare skin disorders.
1683
01:40:06.479 --> 01:40:09.399
We don't do topical gene therapy at this point, but
1684
01:40:09.520 --> 01:40:12.000
we do every other type of delivery.
1685
01:40:13.840 --> 01:40:18.720
Actually, this is an image that was just pulled because
1686
01:40:18.760 --> 01:40:20.920
it was a beautiful image, but actually that's a lot
1687
01:40:21.000 --> 01:40:24.279
what gene therapy looks like. It's a clear liquid I
1688
01:40:24.359 --> 01:40:27.319
think a lot of people wonder what their injection would
1689
01:40:27.319 --> 01:40:30.159
look like, and it is a clear liquid and not
1690
01:40:30.479 --> 01:40:31.560
very scary.
1691
01:40:31.760 --> 01:40:33.159
But very wonderful.
1692
01:40:35.039 --> 01:40:37.920
Now Here is where we're going to show the benefit
1693
01:40:38.000 --> 01:40:41.760
of gene therapy. That's already happening. So on the left side,
1694
01:40:41.840 --> 01:40:45.920
this boy has muscular dystrophy and he's trying to climb stairs.
1695
01:40:46.960 --> 01:40:50.079
And the first place that full of.
1696
01:40:50.119 --> 01:40:52.760
Statin, the gene full of statin that's now often used
1697
01:40:52.800 --> 01:40:56.560
in medical tourism for an aging population was used was
1698
01:40:56.600 --> 01:40:59.800
Induchines and Becker's muscular dystrophy. And this was one of
1699
01:40:59.800 --> 01:41:03.680
the patients. This was him three months after gene therapy.
1700
01:41:05.279 --> 01:41:09.279
Now we're hypothesizing that patients over the age of seventy
1701
01:41:09.439 --> 01:41:12.520
will also need a secondary gene therapy that we're going
1702
01:41:12.600 --> 01:41:15.880
to start using with fullostatin to increase their muscle mass
1703
01:41:15.960 --> 01:41:20.760
and strength due to other delterious effects of biological aging.
1704
01:41:20.840 --> 01:41:22.760
And so you're going to hear about that soon.
1705
01:41:23.199 --> 01:41:27.000
But already we have showed a myriad of successes in
1706
01:41:27.199 --> 01:41:34.159
patients with this gene. Again, according to studies and Chemophilia B,
1707
01:41:35.039 --> 01:41:39.239
with this delivery method, patients thirteen years later are still
1708
01:41:40.520 --> 01:41:45.399
showing expression of gene function, So that's fantastic. So, first
1709
01:41:45.479 --> 01:41:49.800
of all, the area of gene therapy started in fixing
1710
01:41:49.960 --> 01:41:53.399
underlying genetic problems, and this is where it really went
1711
01:41:53.560 --> 01:41:57.960
to show its major successes and what made us realize
1712
01:41:58.000 --> 01:42:03.720
that it had the propensity to problem treat diseases that
1713
01:42:03.960 --> 01:42:09.159
are more complex in order. And these are the therapies
1714
01:42:09.239 --> 01:42:12.680
that are already approved in the gene therapy space.
1715
01:42:12.840 --> 01:42:16.000
So if you think that this is up and coming technology,
1716
01:42:16.039 --> 01:42:16.439
it is not.
1717
01:42:16.720 --> 01:42:21.720
It's already approved by the FDA for thirteen therapies. So
1718
01:42:22.600 --> 01:42:27.039
these are all the therapies that are available now. They
1719
01:42:27.119 --> 01:42:30.239
come with an enormous price take because when you treat
1720
01:42:30.279 --> 01:42:34.680
a small population, you create a very expensive technology. But
1721
01:42:34.800 --> 01:42:39.359
by treating biological aging, we could actually make making these
1722
01:42:39.479 --> 01:42:43.680
type of therapies just free for young patients and patients
1723
01:42:43.680 --> 01:42:45.680
who just need to come up to the line of
1724
01:42:45.760 --> 01:42:54.800
stability with the rest of the population. Preventative medicine is
1725
01:42:54.880 --> 01:42:58.439
probably the best place for gene therapy in those conditions
1726
01:42:58.479 --> 01:43:01.239
that I just showed you. You could consider the gene
1727
01:43:01.319 --> 01:43:04.680
therapy itself a preventative medicine that keeps those children from
1728
01:43:04.760 --> 01:43:09.800
having the outcome of those diseases. If we catch patients earlier,
1729
01:43:09.920 --> 01:43:12.960
we will probably have much more benefit with gene therapy,
1730
01:43:13.319 --> 01:43:18.279
and so I believe that as this technology is shown safe, it.
1731
01:43:18.359 --> 01:43:22.600
Will be used with younger and younger patients.
1732
01:43:24.319 --> 01:43:27.119
On the longevity side, what we can do today is
1733
01:43:27.239 --> 01:43:30.600
we can lengthen your tilomeres. We have so many patients
1734
01:43:30.760 --> 01:43:33.119
data now that shows that we can do that, and
1735
01:43:33.279 --> 01:43:37.000
that's wonderful, and that includes the shortest tilomeres, which are
1736
01:43:37.199 --> 01:43:38.399
very important to target.
1737
01:43:39.000 --> 01:43:41.319
We can increase muscle masks. Definitely.
1738
01:43:41.399 --> 01:43:44.119
I did not work out today, so I'm probably not
1739
01:43:44.239 --> 01:43:48.239
all pumped up, but that is something we can do,
1740
01:43:48.800 --> 01:43:53.239
and that is a beautiful consequence of follostatin gene therapy.
1741
01:43:53.960 --> 01:43:57.239
Now in aging patients who are over a certain.
1742
01:43:57.039 --> 01:43:59.840
Age who don't have precursor stem cells, we are still
1743
01:44:00.000 --> 01:44:04.439
waiting to see how well we can do cognitive enhancement.
1744
01:44:04.720 --> 01:44:09.760
We can accomplish this. I don't want to make any claims.
1745
01:44:09.319 --> 01:44:13.279
Here, but when we do alpha CLOTHO gene therapy, we
1746
01:44:13.439 --> 01:44:18.159
have seen an average increase in a standard deviation of
1747
01:44:18.880 --> 01:44:23.399
IQ tes on IQ tests and that's pretty powerful because
1748
01:44:23.439 --> 01:44:25.600
that could take people who are really low on the
1749
01:44:25.680 --> 01:44:28.880
spectrum and make them more functioning, and people who are
1750
01:44:28.920 --> 01:44:33.720
really high, well it can make them even more awesome. Okay,
1751
01:44:33.920 --> 01:44:38.640
so we need more of those people. So kidney protection,
1752
01:44:39.479 --> 01:44:43.039
that is something that we can do with two gene therapies.
1753
01:44:42.640 --> 01:44:43.079
That we have.
1754
01:44:44.159 --> 01:44:48.119
Mitochondrial therapy. We have a therapy that is specifically for that.
1755
01:44:49.159 --> 01:44:53.279
We are working into five new candidates that we will
1756
01:44:53.319 --> 01:44:57.159
be launching in actually the next six months and getting
1757
01:44:57.159 --> 01:45:01.640
the first human data on, and they all benefit minochondria
1758
01:45:01.680 --> 01:45:05.039
as well. Cardiovascular protection is something we can do with
1759
01:45:05.159 --> 01:45:08.760
one of our gene therapies, metabolic health. Several of our
1760
01:45:08.800 --> 01:45:13.600
gene therapies target metabolic health. Nerve regeneration is something in
1761
01:45:13.720 --> 01:45:17.439
the process, and there's a wonderful gene that is associated
1762
01:45:17.479 --> 01:45:21.760
with re scaffolding. Also, there is evidence that the OSK
1763
01:45:22.039 --> 01:45:24.239
factors benefit.
1764
01:45:24.319 --> 01:45:25.680
Nerve regeneration as well.
1765
01:45:26.159 --> 01:45:29.359
And then of course epigenetic reprogramming that's been all over
1766
01:45:29.640 --> 01:45:31.960
the news and we have our own proprietary form of
1767
01:45:32.079 --> 01:45:32.359
doing that.
1768
01:45:33.000 --> 01:45:35.840
Okay, all right, it's fun to be home because I
1769
01:45:35.880 --> 01:45:38.199
can kind of play around here. So sorry, I've got
1770
01:45:38.279 --> 01:45:39.239
too much energy for you.
1771
01:45:39.920 --> 01:45:43.079
So in ever changing world, we need to genetically modify
1772
01:45:43.199 --> 01:45:49.479
to basically survive the future, survive a dying of death
1773
01:45:49.560 --> 01:45:55.199
and disease, and Jose is definitely behind the crusade to
1774
01:45:55.279 --> 01:45:59.199
make sure that you are aware of our enemies.
1775
01:46:00.079 --> 01:46:04.680
Environment is also an enemy. Living in extreme conditions is
1776
01:46:04.800 --> 01:46:09.800
also an enemy, and so we need to work towards that.
1777
01:46:10.319 --> 01:46:14.199
Enhancing and continual repair is critical for us to get
1778
01:46:14.199 --> 01:46:18.600
the most out of life. We definitely want to stick
1779
01:46:18.720 --> 01:46:21.039
with being able to get out and do the things
1780
01:46:21.079 --> 01:46:24.960
that we love. And I am a huge proponent of
1781
01:46:25.079 --> 01:46:30.640
gene therapy for that integrating technology. Sam Altman was talking
1782
01:46:30.720 --> 01:46:34.520
about how they're looking for genes now to basically help
1783
01:46:34.680 --> 01:46:39.520
integrate technology into you, making it so you don't have
1784
01:46:39.680 --> 01:46:43.840
to maybe lose your devices. Your devices might become part
1785
01:46:43.880 --> 01:46:48.439
of your body. This is fantastic and exciting. And then
1786
01:46:48.520 --> 01:46:52.920
of course exploration of different environments. We know that going
1787
01:46:52.960 --> 01:46:57.159
to space causes accelerated aging. We know that the detriments
1788
01:46:57.720 --> 01:47:01.279
of deep atmospheres also caused damage to our body, and
1789
01:47:01.479 --> 01:47:04.520
so we want to make sure that we're on top
1790
01:47:04.720 --> 01:47:07.399
of that and that we don't limit where we can
1791
01:47:07.479 --> 01:47:12.560
go and who we can go with. So now I'm
1792
01:47:12.640 --> 01:47:15.720
going to talk about some human data, and all of
1793
01:47:15.800 --> 01:47:18.199
this will be my data, because right now I don't
1794
01:47:18.279 --> 01:47:21.760
have permission from patients to release their data. But I
1795
01:47:21.840 --> 01:47:23.920
want to show you what we can do now and
1796
01:47:24.079 --> 01:47:26.720
what we have seen, not just in my body, but
1797
01:47:26.960 --> 01:47:30.119
in other people's bodies as well. So years ago we
1798
01:47:30.279 --> 01:47:34.479
released a paper on my data. We showed that since
1799
01:47:34.520 --> 01:47:37.720
my first gene therapy and my second gene therapy which
1800
01:47:37.760 --> 01:47:39.960
gave me a little bit of a boost of telomeri's
1801
01:47:40.000 --> 01:47:44.079
reverse transcript case. This is a gene therapy that lengthens
1802
01:47:44.119 --> 01:47:48.680
the caps at the ends of the chromosomes. These shortening
1803
01:47:48.920 --> 01:47:52.399
of these caps are associated with a myriad of disease.
1804
01:47:52.960 --> 01:47:54.720
As a matter of fact, all the diseases of.
1805
01:47:54.760 --> 01:48:01.279
Aging and critically short telomeres lead to increase risk of
1806
01:48:01.399 --> 01:48:07.159
genomics instability, which causes cancer. There are a lot of
1807
01:48:07.359 --> 01:48:09.880
different things that I can tell you, but this would
1808
01:48:09.920 --> 01:48:12.880
be a talk all on its own. Since my gene
1809
01:48:12.920 --> 01:48:17.359
therapy is in twenty twenty five, my tilomere length has
1810
01:48:18.319 --> 01:48:21.159
lengthened by an average of five point three years for
1811
01:48:21.319 --> 01:48:25.279
every year I've lived, and my tilimeres are longer since
1812
01:48:25.359 --> 01:48:28.920
these results, and I need to get this year's tilomere
1813
01:48:29.000 --> 01:48:32.479
test done so then we'll have twenty four and twenty
1814
01:48:32.560 --> 01:48:35.439
five and then a release more information.
1815
01:48:35.880 --> 01:48:41.039
Very important short tilomeres in your immune system, which are
1816
01:48:41.079 --> 01:48:42.800
the tilomeres that we actually test.
1817
01:48:43.640 --> 01:48:50.119
Short tilomeres were associated with deaths in COVID nineteen. Number
1818
01:48:50.159 --> 01:48:52.439
one association was immune senescence.
1819
01:48:52.960 --> 01:48:55.840
Whether you're young or you're old, you need.
1820
01:48:55.800 --> 01:48:59.279
To have cellular division in the immune cells or they
1821
01:48:59.399 --> 01:49:04.960
cannot divide to attack an infection. So it goes beyond
1822
01:49:05.239 --> 01:49:11.600
just chromosomal stability and living longer in certain benefits of that. Also,
1823
01:49:12.239 --> 01:49:17.760
things like lobsters and certain clams, they may be living
1824
01:49:17.840 --> 01:49:20.840
as long as they do, which is in extremely long
1825
01:49:20.920 --> 01:49:24.399
time hundreds of years due to having to lameris turned
1826
01:49:24.479 --> 01:49:26.960
on in every cell. So I am a proponent of this.
1827
01:49:28.039 --> 01:49:30.720
We have not seen drawbacks or adverse drug events, and
1828
01:49:30.800 --> 01:49:32.920
we've watched patients for over five years.
1829
01:49:35.359 --> 01:49:36.119
Full of satin.
1830
01:49:36.520 --> 01:49:39.439
We can increase our muscle mass as long as you
1831
01:49:39.520 --> 01:49:42.319
have precursor stem cells, and we'll be able to increase
1832
01:49:42.359 --> 01:49:44.920
your strength even if you don't. And we'll talk about
1833
01:49:44.920 --> 01:49:47.399
a company that is going to help replace those stem cells.
1834
01:49:47.439 --> 01:49:51.560
Anyway, this is my results that were put out.
1835
01:49:51.880 --> 01:49:57.000
This is my MRI image and my muscle mass increased,
1836
01:49:57.119 --> 01:50:01.359
and my intramuscular fat went down. Full of statin comes
1837
01:50:01.399 --> 01:50:03.119
with a bunch of benefits. If you look at the
1838
01:50:03.199 --> 01:50:07.760
literature review around it, it's kind of crazy. It helps
1839
01:50:07.800 --> 01:50:12.239
with tissue repair, regeneration, It turns down inflammatory markers. We
1840
01:50:12.359 --> 01:50:15.880
believe that re establishing the immune system is dependent on
1841
01:50:16.039 --> 01:50:19.600
turning down these markers. That the things that we used
1842
01:50:19.640 --> 01:50:22.880
to think actually major immune system really strong, which was
1843
01:50:23.039 --> 01:50:27.760
stressors and inflammation, actually keep it from rebuilding your body.
1844
01:50:28.479 --> 01:50:30.000
And I'm working with a.
1845
01:50:30.039 --> 01:50:32.520
New company that's going to be showing that in human
1846
01:50:32.640 --> 01:50:34.279
data over the coming year and a.
1847
01:50:34.279 --> 01:50:37.319
Half, So this is really important.
1848
01:50:37.760 --> 01:50:41.000
It may actually even have a protective role that's full
1849
01:50:41.039 --> 01:50:44.279
of statin in prostate and breast cancer, and that's something
1850
01:50:44.359 --> 01:50:47.600
that we're going to want to watch and see. And
1851
01:50:47.720 --> 01:50:53.119
of course, increase muscle mass is associated with insulin sensitivity,
1852
01:50:53.279 --> 01:50:57.760
which is vital to not have type two diabetes. Again,
1853
01:50:58.000 --> 01:51:01.119
we will have growing evidence there. When we talk about
1854
01:51:01.199 --> 01:51:04.680
brain health, we often talk about alpha CLOTHO and one
1855
01:51:04.720 --> 01:51:07.560
of the things that my company wanted to do starting
1856
01:51:08.000 --> 01:51:13.000
in maybe two thousand and sixteen or seventeen after I
1857
01:51:13.119 --> 01:51:16.920
was treated, is learn how to redose aav We're the
1858
01:51:17.079 --> 01:51:20.439
only company in the world that can do it that
1859
01:51:20.600 --> 01:51:23.439
we know of, and we wanted to prove that we
1860
01:51:23.560 --> 01:51:27.840
were having a therapeutic effect even with redosing events. So
1861
01:51:28.880 --> 01:51:32.119
on the left side you see my alpha CLOTHO levels.
1862
01:51:32.199 --> 01:51:36.119
This was after I had already been treated in twenty twenty.
1863
01:51:37.000 --> 01:51:39.960
But what it shows is that I'm in the ninetieth
1864
01:51:40.079 --> 01:51:44.319
percental for alpha CLOTHO for my age, and that's fantastic.
1865
01:51:44.439 --> 01:51:47.199
That means the first gene therapy probably worked.
1866
01:51:48.880 --> 01:51:52.840
Then we did a redosing protocol and on the right
1867
01:51:53.000 --> 01:51:56.399
side that is an increase to the ninety fifth percental
1868
01:51:56.560 --> 01:51:57.439
for alpha clotho.
1869
01:51:57.960 --> 01:52:00.760
And since then, I think my school or because we.
1870
01:52:00.800 --> 01:52:06.279
Did it again, I just keep doing it and now
1871
01:52:06.359 --> 01:52:09.920
it's one thy three hundred and I think twenty eight.
1872
01:52:10.159 --> 01:52:14.159
So now I'm basically hovering in the top area.
1873
01:52:14.600 --> 01:52:17.039
I don't really want to go over that where we
1874
01:52:17.159 --> 01:52:19.920
want to get the alpha clotho in the maximum area.
1875
01:52:20.279 --> 01:52:23.279
We don't want to take it over what would be
1876
01:52:23.720 --> 01:52:27.680
natural for a human homeostasis at this point, so I
1877
01:52:27.880 --> 01:52:30.520
will be working on some other.
1878
01:52:30.479 --> 01:52:31.960
Data years ago.
1879
01:52:32.319 --> 01:52:36.000
Let's see, this was in twenty twenty one we launched
1880
01:52:36.000 --> 01:52:38.880
a paper of a safety study with h turt and
1881
01:52:38.960 --> 01:52:43.520
alpha CLOTHO and patients with dementia and we saw a benefit.
1882
01:52:43.840 --> 01:52:46.840
And I actually took this to the US FDA and
1883
01:52:46.960 --> 01:52:49.319
did a pre I ind on it, and they asked
1884
01:52:49.399 --> 01:52:52.479
for eight million dollars worth of animal studies even though
1885
01:52:52.520 --> 01:52:55.520
we had human data. So that was at the point
1886
01:52:55.600 --> 01:52:58.399
that we tipped, and we started licensing out to other
1887
01:52:58.560 --> 01:53:01.399
companies who could use it in the locations they were in,
1888
01:53:02.199 --> 01:53:05.479
or could they had the aptitude and the fortitude to
1889
01:53:05.640 --> 01:53:08.560
raise the money to get into the US FDA. And
1890
01:53:08.800 --> 01:53:10.880
I'm happy to tell you we've got new two new
1891
01:53:10.960 --> 01:53:14.319
groups coming on to use this therapy and patients with dementia,
1892
01:53:14.359 --> 01:53:16.000
one in the US and one in the Bahamas.
1893
01:53:16.000 --> 01:53:19.000
But we'll talk about some more coming up here. But
1894
01:53:19.159 --> 01:53:19.880
what happened.
1895
01:53:20.720 --> 01:53:24.479
Cognitive scores went up and biological age went down.
1896
01:53:25.039 --> 01:53:28.560
It was not a cure, but it did offer.
1897
01:53:28.399 --> 01:53:31.640
Hope for some of these patients, and one patient went
1898
01:53:31.720 --> 01:53:34.720
from living in assisted living to living on their own.
1899
01:53:36.039 --> 01:53:38.680
We really want to work this towards a medical cure.
1900
01:53:39.239 --> 01:53:42.600
These were incredibly low doses. We're hoping with higher doses
1901
01:53:42.800 --> 01:53:46.479
and the insertion of a third gene that we want
1902
01:53:46.560 --> 01:53:51.720
to use, we're going to get better results. So what
1903
01:53:52.079 --> 01:53:56.199
happens if we keep curing mice, but we can't get
1904
01:53:56.239 --> 01:53:59.359
things to humans. As you know, all of you probably
1905
01:53:59.479 --> 01:54:03.279
know not get into this industry to do research and development.
1906
01:54:03.439 --> 01:54:06.199
I got into this industry to help patients, and that's
1907
01:54:06.239 --> 01:54:07.600
why scientific.
1908
01:54:07.239 --> 01:54:11.119
Accuracy is so important for me. We're a different beast.
1909
01:54:11.760 --> 01:54:14.199
We believe that if you've got good medicine, you'd be
1910
01:54:14.359 --> 01:54:17.800
using it, and if you're not, we're going to put
1911
01:54:17.840 --> 01:54:19.720
you to the challenge of getting it up there.
1912
01:54:20.560 --> 01:54:23.680
I've spent about a third of my time in regulations.
1913
01:54:24.000 --> 01:54:27.960
I worked in a myriad of zones, one zone that
1914
01:54:28.880 --> 01:54:32.960
actually approved their regulations last year to use gene and
1915
01:54:33.039 --> 01:54:36.640
cell therapy, and I will continue to push for new
1916
01:54:36.880 --> 01:54:40.039
innovative areas to open up for the use and access
1917
01:54:40.079 --> 01:54:44.840
of these technologies, including the United States. We work with
1918
01:54:45.439 --> 01:54:50.840
several concierge medicine companies, and these are healthcare companies that
1919
01:54:51.119 --> 01:54:54.720
basically you're given a special person who handles your dossier
1920
01:54:55.279 --> 01:54:58.800
and they help you get access to technology.
1921
01:54:58.359 --> 01:55:00.479
All over the world. This is a Swiss group.
1922
01:55:00.640 --> 01:55:04.239
They have clinics in Switzerland and we also work with
1923
01:55:04.399 --> 01:55:07.399
clinics all over the world with gene and cell technology
1924
01:55:08.239 --> 01:55:13.079
and almost anything that is very high value that would
1925
01:55:13.119 --> 01:55:16.399
be hard to get through a normal system. We also
1926
01:55:16.560 --> 01:55:20.039
have these four licensing partners on top of a couple
1927
01:55:20.199 --> 01:55:23.439
other ones. We've just added. Future Health is in China.
1928
01:55:24.159 --> 01:55:26.840
They're a fantastic group. They're starting to work with a
1929
01:55:26.920 --> 01:55:30.640
Chinese government in ninety two hospitals to move technologies forward.
1930
01:55:31.439 --> 01:55:34.600
On the upper right side is an Unlimited Bio. They've
1931
01:55:34.600 --> 01:55:39.960
been working in Honduras and they treated a Kardashian. Hey,
1932
01:55:40.159 --> 01:55:43.239
that is really cool. They're a cool group, very cool group.
1933
01:55:44.279 --> 01:55:47.119
On the bottom left is Integrative Health Systems. They have
1934
01:55:47.239 --> 01:55:51.039
treated over three hundred patients without an adverse drug event
1935
01:55:51.640 --> 01:55:55.039
and knock onward. We're very proud of them and they're
1936
01:55:55.039 --> 01:55:58.520
an incredible group of thirteen medical doctors and a concierge
1937
01:55:58.600 --> 01:56:01.920
system that helps with all the pre impost and all
1938
01:56:02.000 --> 01:56:03.159
the travel arrangements.
1939
01:56:03.680 --> 01:56:05.600
And on the bottom right is a group I was
1940
01:56:05.680 --> 01:56:07.680
going to talk about. That's re gen Cell.
1941
01:56:07.840 --> 01:56:11.399
They're working on replacing your stem cells, but not just
1942
01:56:11.560 --> 01:56:16.680
replacing your stem cells, reprogramming them and adding genetic function
1943
01:56:17.000 --> 01:56:19.760
to them. And so you're going to hear more about
1944
01:56:19.880 --> 01:56:23.720
them over the next couple of years. And that is
1945
01:56:24.000 --> 01:56:27.239
a super benefit because for people over the age of
1946
01:56:27.319 --> 01:56:30.199
sixty five, they're down to five percent of their stem cells.
1947
01:56:30.319 --> 01:56:33.000
And without these stem cells, you cannot regenerate your body.
1948
01:56:33.720 --> 01:56:37.000
So these are very very important cells to the body.
1949
01:56:37.079 --> 01:56:39.880
So they need to be replaced. And if they're reprogrammed first,
1950
01:56:40.960 --> 01:56:43.119
that's a benefit. And if they have better gene function,
1951
01:56:43.399 --> 01:56:49.760
even cooler. So I know that we move quickly, but
1952
01:56:50.279 --> 01:56:54.960
we are an engine for change. We are humanitarian group
1953
01:56:55.319 --> 01:56:59.800
of scientists, medical doctors and business people who believe that
1954
01:57:00.359 --> 01:57:03.600
we need to spend our time for the betterment of humankind.
1955
01:57:04.399 --> 01:57:07.000
And so I want to leave you with this quote.
1956
01:57:07.600 --> 01:57:12.279
He who rejects change is the architect of decay. The
1957
01:57:12.439 --> 01:57:17.359
only human institution which rejects progress is the cemetery. I
1958
01:57:17.600 --> 01:57:29.760
suggest you don't land there. Thank you so much, thank you,
1959
01:57:30.199 --> 01:57:31.159
thank you very much.
1960
01:57:31.359 --> 01:57:31.640
Liz.
1961
01:57:32.199 --> 01:57:37.840
We we love you, but we have to say goodbye,
1962
01:57:39.479 --> 01:57:47.640
good bye, goodbye, thank you, thank you, bye bye.