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Welcome to Longevity. I'm your host, Natalie Nidom. I'm a nutritionist, a human potential
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and epigenetic coach, and I created this podcast to bring you the latest ways to take control
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of your health and longevity. We cover it all from new technology and ancestral health
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practices, to personalize interventions, and a very special interest of mine, peptides
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and bio regulators. Enjoy the show. Welcome back to the show. Everybody, my name is Natalie
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Nidom, and I am your host. Now, before we get started, very quick favor. My Instagram
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account has, well, let's just say it's vanished. And I'd really still love to share and be in
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touch with all of you. So if you want to stay up to date and stay in touch with me, aside
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from signing up for my newsletter at natnidom.com, you can also follow me at my new Instagram
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account, which is at longevity with nat. Okay, let's get into this episode. Kyle Vendor
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Least is back. His story may sound familiar to you, mold illness, love of food of medicine,
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a death of someone near and dear to him in his family, and a drive to engineer formulas
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that actually work. We're digging into how he builds formulas from the ground up, focusing
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on mechanisms, not just ingredients, expect blunt truths about product quality, why you
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should care about bioavailability, and how he balances long-term outcomes with fast
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acting wins for brain and gut health. Now, if you want to learn more about any of Kyle's
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level up formulations, head on over to leveluphealth.com and use code nat for 20% off. And level up has
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no ease in it. L-D-L-U-P-H-E-A-L-T-H.com and use code nat. Next up, we'll thank a couple
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sponsors that make this podcast possible and then we're off. What if doing less actually
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helped your body do more? We're constantly adding things to our routines, more supplements,
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more workouts, more products, more protocols. But if your body is stuck in stress mode,
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none of it really lands the way it should. Your wire tired and never really quite recovering.
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Now one thing I keep coming back to is my infrared sauna, not as a push harder tool, but
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as a reset. A few sessions a week, sometimes short, sometimes longer depending on how I feel,
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and it helps my body shift gears. Infrared sauna therapy uses light energy, not just heat,
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to gently warm your body from the inside out. That supports mitochondrial energy, circulation,
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detoxification pathways, and most importantly, your nervous system. And I use sun lighten because
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they've been leading this space for over 25 years. Their full spectrum infrared plus integrated
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red light makes it a one-stop session. And they have options that actually fit real homes
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and real budgets. Everything from your full cabin sauna to a solo portable version.
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So if you're building a smarter longevity routine, this is a foundational piece.
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Learn more and save up to $1,600 plus get free shipping on your sauna purchase when you visit
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sunlighten.com and use code net longevity. I didn't realize how on edge my body was until it
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finally wasn't. You know that feeling where you're technically sitting still, but your nervous
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system is still sprinting. Like your body didn't get the memo that the workday is over. Well,
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I felt just like that. So instead of piling on more supplements or trying to force relaxation,
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I started using Apollo Neuro as part of my daily routine. Apollo is a wearable device that I
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am now addicted to. You wear it on your wrist or your ankle or even clip to your t-shirt around
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your neck and it delivers vibrations to your body for completely different nervous system needs
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as they come up. So what's different here versus any other vibration wearable is their smart
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vibes tech. It's not just a one size fits all vibration. It actually learns your patterns.
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I can manually manage it or I can leave it and it adjusts based on what my body needs.
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So it feels less like I'm doing something and more like my system is being guided.
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It's literally like a dimmer switch instead of an on-off button. Over time,
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I've noticed I'm more steady during the day, way better at shifting into rest mode at night.
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I sleep better and I even see my HRV numbers improving. So if your nervous system feels like
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it's stuck in overdrive, this is probably worth a try. There are modes for focus, sleep,
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calming anxiety, increasing performance and so much more. Just head on over to ApolloNuro.com
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forward slash NAT and use code NAT and you get to save 99 dollars on your purchase.
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Kyle Vendor Least, welcome back.
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Man, that's eating it. I'm round four. Thank you for having me back.
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Is it round four? Is that it? Four or five. It's kind of a lock of it. It's been a journey over
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the years and it's good to break connect again. It's been a hell of a journey since then and
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your company have exploded incredibly over the last number of years and it's been a total
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honor to watch you expand the way that you have. It's been really amazing. To that end,
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you've gained so much knowledge, insight and experience as you've been going. In your opinion,
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what's the biggest mistake you feel they're people are making when they try to fix their health
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and why do most supplement stacks actually tend to make them worse?
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One of the biggest mistakes, definitely, this is it, is just jumping on Amazon or I have and
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doing a quick GPT or Google search of what can help and then they just go straight to the bottom
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end for the price. One thing I've always had to apologize for but kind of unapologetically,
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it's the reality of the brand is we are expensive for a reason. Every product, every ingredient
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we source goes through rigorous testing, quantitative, qualitative analysis, looking at the
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constituents, quantifying what percentage of the herb actually has that constituent because
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the studies that show that a botanical extract or a vitamin does something for a disease condition
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or for cognitive enhancement or for gut health is very specific to the active found in that botanical.
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And if you just hear the word like cordyceps mushroom or something like, oh, zinc helps and then
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you just go on and you're like, oh, here's the cheapest cordyceps. There's a good chance that
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that's just absolute bug material or the industry has cut it where you get 500 milligrams of a
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cordyceps blend and they've just given you all the useless parts of it and the actual active that
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you'd want in a milligram quantifiable amount is not even in there at all or if it is, it's in my
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program amounts versus milligrams. So that's the biggest mistake that people make and I think
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the industry is getting a little better to this as people wise up to it and as we push the education
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around quality and get deeper into the mechanism of exactly and implicitly what you want from a
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from a supplement and even in solo ingredient ones. It's super simple. The formulas are a bit more
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complicated but yeah, that's probably the biggest mistake I see people make and then on the flip
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side after they try things and they don't work, they just go back to, if that's their entry point
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to supplements, why wouldn't you go back to pharmaceuticals when they hit you and work hard and
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then that supplement did nothing. So it's a it's a cry when people say supplements don't work
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because they absolutely do. There's just a big percentage of supplements on the market that
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actually don't so yeah. Yeah, no, that's a that's such a powerful point. People are chasing
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symptoms but they don't really often understand what the drivers of the symptoms are and so
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you take a supplement to address the symptom that doesn't really get to the reason why the symptom
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is showing up. That's probably the next layer if you will of it didn't work for me and that's
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because it wasn't what you needed. Yeah, exactly right. Symptom chasing is in naturopathy called
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green alapathy where we just replace a drug with a supplement that might alleviate a symptom and
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not really go for the root cause. So if you want to be on supplements for caring to try and manage
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manage a condition at the most downstream part of it, that's fine if that's your choice but
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definitely digging deeper and trying to find the root cause. There's always like if a
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car's broken or an engine like goes on you'd go straight for the problem and try and fix that
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rather than just taping over the light or fixing like a fuse or something in it. So yeah, we can
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definitely do a lot better that way. We've had you on the show a couple times so your origin story
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runs through those previous episodes and will this the episodes in the show notes? But for anybody
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who's new to the show and who doesn't know you, what's your two minute pitch on what you do and why
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you do it? Yeah, so I'm a trained naturopathy nutritionist from Australia. My big why behind starting
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level up is I was a primary my the primary career from my mother who had she passed but she had
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cancer and it was an eight year battle and we tried all of the supplements, all of the peptides,
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all of the biohacking things and my goodness eight years with eight years with that diagnosis that
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she had was it far exceeded any expectations people had with her and that's sort of what sparked
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my interest in supplements is is nutritionist food is medicine. What's in the food that's the medicine
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is when you get isolated supplements where they sort of distill that out of the food and super
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concentrated in in a pill. Beyond that, I've been through health challenges. I've spoken about
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Moldoric in about three of three of the podcast we've been on the first one as much but
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that was a journey and it absolutely tanked my own health and silver lining to that is a formula
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aid at risk. When you have a health problem and you have the accessibility to ingredients and
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that I do as well as the peptides you can figure out some pretty innovative ways to get better a lot
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faster than just relying on other brands attempts at liver detox support formulas or other
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neutropics to get you through it. So there's been a huge expansion of level up health's range basically
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centered around Mold for me but now that I'm not in Mold anymore and thriving I'm kind of looking
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to just have these little upgrades to sort of everyday health products. Nice I love it.
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All right so here's something that a lot of people might not know about you is that you're not
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just pulling from one discipline. You're blending naturopathy biochemistry traditional medicine
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and that discipline that we call biohacking whatever the heck that means anymore. So where did that
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hybrid thinker mindset come from? Like you you really because a lot of people say okay this is
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the way or this is what I'm going to do and you instead are like ah there's a buffet out there.
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Yeah one of my mentors said anyone who claims to have all the answers is that's the biggest red flag.
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Like I am clinic directors, chiropractors, osteopaths they all not all of them are becoming a lot
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more holistic minded but anyone who's ever claimed that this is the thing is just trying to make money
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out of you. I had to try and figure out in supplements or what would work like I have often used
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off-label medicines and stuff like that like no lotus no trexone I've spoken about that's pharmaceutical
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methylene blue technically is pharmaceutical I love both of those things they're fantastic.
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The golmura of a naturopath would usually prevent them from ever touching a pharmaceutical or
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something synthetic and just rely on nature and the herb and then the intelligence of that.
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Yeah didn't really resonate with me as strongly as using things that absolutely you can feel
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and technically and on like blood tests and mold texts organic acid tests or a stool sample you can
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see quantifiably the change happening so much faster than any other thing so that's sort of
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wire blend modalities it's just outcome based rather than you know sticking to a dogma
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of nutritionist or naturopath or whatever the heck you want to call yourself by a hacker.
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All right well how can everyone everyone can be a health coach if they decide to be on their
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profile for that qualification. Yeah no kidding so here's what we thought would be fun for today
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is if we were to discuss some common issues people deal with and the naturopath
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formulators approach to building the formulas that actually help. Are you game?
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Oh yeah oh yeah semi-quick five and I definitely get derailed into tangent so you'll have to
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I'm counting on those tangents that's where the that's where the magic is okay so when you sit down
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to create a formula what's your starting point is it symptoms pathways outcomes where do you
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where do you begin. Usually it's around the mechanism mechanistic drivers like that is the
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high-level thing like what are the key mechanistic drivers of this condition or this problem
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let's just focus it on like stress for example if we look at why someone stressed it could be
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like cortisol is the big one you want to hear it right and then adrenals adrenals might be
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malfunctioning it's stripping it back to what are all of the foundational drivers of
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of the problem you're trying to solve so try to solve the problem not create a product that might
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just happen to help with problems um liver complex that um been selling for a few years now as a
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perfect example of that we've done a whole podcast explaining the methodology behind that but
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essentially with that formula I looked at if the liver is going to detox if you're going to support
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liver health how does the liver work not what ingredients help liver and it's phase three detox
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file flow and then phase two conjugation and then phase one as well as anti-oxidant support and
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glutathione they're like the big ones there's always going to be a mechanism or another pathway that
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makes up a percentage that you just can't hit unless you like your formulas to have 40 ingredients
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which sometimes I've gotten close but generally generally I like to keep it more than like six to
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eight in a product and yeah and then concurrently too it's the next step to it would be all right we
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know the mechanisms what are the candidate ingredients for it let's look at the studies let's look at
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the research let's you know figure out what's moving the needle the most as well as frankly speaking
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I find it as useful as reading a study it's just going on forums seeing people's experience and
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like these out resounding success stories or feedback from people really triggers triggers me to dig
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deep as to how that might have happened a really good naturopathic herb that's triggered the
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shit out of me for a few years it's called indigo naturalis and I found out about that through
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a forum you interviewed Dane from Crones Collider's lifestyle a few years ago yeah he put out like a
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survey amongst this community of all of these products which ones helped you with your flair your
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colliders flares the most and that one topped mine for number two the GI repair and like ridiculous
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as if this silly little herb is helping more than my ultimate GI but I mean the user experience is
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something that's absolutely prompted me to try and bring that out because if that's helping who
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will might argue with the hundreds of people who share the best thing for their their flares for
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their IBD so those user experience things are definitely a huge factor that goes into how I
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formulate the next thing is picking the quality materials that's one of the harder things that
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you need to have a lot of discernment if you're formulating you can't just go on Google you can't
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just go on iHerb and see how the other people are doing it because a multivitamin can have synthetic
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b9 synthetic b6 cyanocabolamin instead of methylcabolamin or adenosylcabolamin and then you just
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might as well not even use the stuff yeah or you might hurt people by giving a material that needs
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methylation or it needs you know certain genetic strengths to convert it to something usable and
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for a lot of people those things can be detrimental to their health and making sure every ingredient I
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select does no harm that is the you know Dossore the doctor mantra basically first do no harm
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that's yeah how to formulate and honestly peptides do you have the ability to do it that's
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why I've started steering a little bit away from them now despite them being the foundations of
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business still mm-hmm yeah I mean the peptide story is well we'll get to it but well actually
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here's here's leads us to an next question so how do you decide between using a peptide
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or a vitamin when they all might target the same issue because the peptides pretty sexy everybody
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wants the peptide right so how do you decide yeah well usually when I formulated it's like let's
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anchor the product around a peptide that's going to do the heavy lifting you might if 100% of the
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formula is effectiveness if the peptide contributes 60 to 70% fantastic that's great let's not overlap
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the mechanism let's not use redundancy like redundant products or redundant ingredients but
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let's have things that sort of if BPC is triggering like epithelial growth factor veg F
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nitric oxide all those other pro healing pathways let's bring in hyaluronic acid which
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BPC doesn't stimulate hyaluronic acid that's a building block let's use PEA which is actually
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going to symptom relief the pain where BPC won't do that that's how I'd like to formulate
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overlapping for the actual outcome but not overlapping the mechanism unless you know you're not
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hitting that mechanism strongly enough with one ingredient yeah so what's something that most
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consumers and even practitioners completely misunderstand about ingredient synergy what what are
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people missing here ingredient synergy well I think I see it in the pre-workout space is synergy
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can be detrimental because if you hit a pathway the best one that I can explain and that I often
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accidentally overdue is acetylcholine as a like metropics so acetylcholine is the is the
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neurotransmitter associated with focus mental clarity speed and just how quickly you can recall
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your words yeah however you can push this too high and there's ingredients like alpha gpc cdp
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colline it's the other one there's a few other colline sources they are like donors of colline
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but then if you take something like hupazine serrata or hupazine A that's acetylcholine esterase
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inhibitor so it keeps that acetylcholine in your in your your own for too long and then you
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kind of overshoot it and then you get these headaches absolutely pounding headaches and all the
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focus that you had has completely been wiped away by the headache so it's really easy to there's
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always a inverse u-shap curve for dosing things and I see people just pushing things way too hard to
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try and like be a race to the claim like who has the most of this ingredient or if you can do it
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the best and the biggest and it's almost like ikawik from the formula I do more than you mine's
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bigger and sort of thing so that's one way that it's going wrong the other thing that
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I noticed is proprietary blends that I'm not even going to get into why they're problematic but
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essentially they hide things yeah in the sense that proprietary blend just allows a business or
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a company to hide expensive ingredients in that proprietary blend and basically use none of it at
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but still be able to climb it on the level yeah yeah yeah I just talked about that in a solo
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episode and the proprietary blend unless they're you know you'd get a proprietary blend that because
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the rule I guess that they made was that you only had the manufacturer only has to give the total
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weight of the blend but doesn't have to assign weight so if you have 10 ingredients in a proprietary
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blend that accounts for 500 milligrams of supplement and two or three of those need 150 or 200
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milligrams to be therapeutic you got a problem yeah and usually in a proprietary blend you'll
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find one ingredient that you probably people probably don't know what's a cheap ingredient what is
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a cheap ingredient and what's an expensive one but usually there's always a cheap ingredient in that
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proprietary blend a perfect example is lion's man mushroom so in lion's man you can have really
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high extract ratio so like a 200 to one or something like that or something standardized to a certain
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amount of an active that you're after but the other thing you can do is just blend in the whole thing
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lion's man's probably a bad example because if you do take the whole mushroom it's fine yeah
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we look at a whole herb maybe the leaf or the root is the only part of that herb that has the
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active that you're after but they'll put the the root in there be able to claim that our
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licorice roots in this yet they'll chuck the whole licorice plant leaves and all and then it
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it dilutes down the um actual part that you're after and essentially makes a product that's not
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going to work well at all but um you know it ticks all the boxes for consumers when they're looking
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to buy it yeah yeah no that's a really good point actually another good example of that is ashwagando
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where you don't want to be using the aerial parts of the plant you don't want to be using the leaves
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because there's toxins in there but that's cheap that's a cheap source of the active ingredients
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you're looking for so the cheap ingredients will use that instead of the root how do you balance
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the trade-offs or how do you think about trade-offs for example faster immediate results which
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everything everybody's after versus long-term adaptation it's always a hard one because the long
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term stuff the long play like one of our products longevity isn't one you feel immediately that
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but it is one of the most accumulative effect one of the best for accumulative effects if you
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continue to use it it's a build up effect another one is PEA it's an anti-inflammatory pain killer
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one yeah if you use it for up to a month that's when you get the best effects you still feel some
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effect in the front end um and for things like BPC or zinc or copper it's definitely
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there are potential trade-offs to long-term use so whenever I talk about taking supplements like
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everything in the range I don't want people to be on these for the rest of their life the only
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exceptions may be creative for example like if you're on that for the rest of your life that's
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probably just a smart investment and making sure your brain in muscle works better but things
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like the neuro formula the ultimate GI anything peptide based I always tell people to take a break from
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because continued use is a trade-off um the what's like an immediate problem in taking things I
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mean you can get I'll give an example we sold some test offensive for a while for like a week that
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shouldn't have done it yeah so like for disclosure we you know you know how do I thought this
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is amazing this is going to be like the next generation weight loss thing and arrival all these
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ozempics and GLP ones and and then I got it made to a high standard and wholly smokes it just
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exposed to me that no one else in the industry does that ingredient properly because when we made
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it and we made it suspect I was sweating profusely for four or five hours because that's the trade-off
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to this thing it increases damage and this is so much as well as um parasympathetic tone that you
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get all these host of side effects and it ended up feeling like horrible pharmaceutical and we
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just pulled that completely from circulation that was a lesson learned for future products to not
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push things too hard too fast and uh make sure that you find that nice balance point again similar
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to how I said like every ingredient has its optimal dose on the inverse U shaped curve well every
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ingredient that I put into them I kind of figure out where that needs to be based on evidence and also
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you know potential for long term harm or accumulative effects for example might be detrimental like
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zinc we could put more zinc in ultimate GI or higher doses but then the zinc to copper
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ratios will be thrown out so much faster yeah there's there's like a um definitely a balancing
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act everything let's talk about the zinc in ultimate GI because the number next to zinc is not
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the actual amount of zinc you're getting and that's very confusing to people people
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I've had comments from people saying oh I can't take that there's way too much zinc in there
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do you want to explain a little bit about the type of zinc that you're using and why it looks
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like it's a lot but really it's not I'll go a bigger picture at the start every single um mineral
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is killated or bound to something magnesium copper zinc sodium all of the electrolytes are bound
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to something always potassium citrate magnesium glycinate zinc alkanacene zinc piculinate or
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zinc this glycinate there's always something you don't ever get the thing in isolation it has to
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be you in supplements at least it's bound to things in diet it might be different but
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so zinc alkanacene which we use in GI repair that specific form of zinc alkanacene is selected
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because the alkanacene that the zinc is bound to is super beneficial for gut inflammation
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and all the alkanacene also allows the zinc to essentially hang around and elicit its effects in
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the gut for a lot longer and doesn't drive systemic absorption as much as it as it promotes
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local zinc saturation in the lumen so for taking a zinc supplement to rectify zinc deficiency
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for example a zinc alkanacene is not going to be as beneficial as a piculinate or a gluconate
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or something like that because it is targeted and designed for the gut it will get in circulation
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it's not to say that's a useless form but there are better forms of doing it magnesium is a fantastic
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second example because it's still a mineral and there's many different forms of which many
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people are interested in magnesium al3n8 I'll use to explain what you said about the dosing
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the dose for magnesium al3n8 is 2,100 milligrams and of that only 151 milligrams is actually
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magnesium the rest of that complex of that pairing of magnesium and al3n8 is al3n8 so
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different forms have different percentages and this is always a consideration for formulating
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because if you want to deliver an elemental amount so when you're looking at minerals you
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want to see the elemental yield or the elemental amount or equivalency that is the actual amount
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you want so like for magnesium I always like to aim for 350 to 400 milligrams if you were to try
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and get that exact amount from al3n8 you're going to have to take 4 grams worth of magnesium al3n8
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to get that amount of magnesium in circulation there's other forms you can use like magnesium oxide
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terrible absorption but 50% magnesium and the reason it doesn't absorb and gives you the runs
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is there's just too much magnesium relative to oxide and it pulled water into the into the
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gut and then you end up having the runs you can make a form of magnesium oxide called sucrezone
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or magnesium where they take that magnesium oxide that almost 50% blend of magnesium to oxide
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and then encapsulated in a sucrezone like a sucrose like lipozone and then that gets it into
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circulation and then if that you know once the magnesium oxide is in circulation then you've got
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a huge amount of magnesium that's actually made it into circulation and not caused all the GI
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upset but anyway in short the reason why you don't have to the the thing to look for and when
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dosing is the elemental amount for that the other caveat to it is when you're looking at ingredients
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like phosphatidal colon phosphatidal serine this is something manufacturers and supplement companies
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often do is you can select the percentage yield of that active like phosphatidal serine for example
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amazing for stress and focus and cortisol regulation when selecting material you can choose a 50%
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phosphatidal serine blend and basically the other 50% of that would be phospholipids and
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unfortunately and we have to spend a lot of time now excluding material suppliers often the other
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50% of that material that you're putting into your product is rice flour or cellulose or something
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like that so a lot of supplement companies whether they know it or they're just ignorant to it
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we're trying to give you 250 milligrams of phosphatidal serine but they haven't dug into the report
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from the supplier or they haven't done the third party testing to say that all that 250 milligrams
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is only 50% so the amount that you're delivering is actually meant to say 125 and this is
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something that you know we nearly got tripped up on with that particular ingredient and phosphatidal
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colon as well when the higher you go in the yield and the active the more expensive it gets because
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you are just getting what you want and what you know what is the ingredient you should deliver so
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that's another thing to to look for and often if you take a supplement that seems
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like for like versus another one and one works and the other one doesn't that's probably because
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the one that doesn't work is part of those complexes or those blends so when you're looking at someone's
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supplement stack what's a green flag versus a red flag for you what are the flags you're looking for
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I always like to see people have a magnesium in their stack I think everybody kind of needs
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magnesium nowadays making sure that they've got good forms or a blend of magnesium like we do
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one bio optimizers do a good one shout out for them for doing something well in the industry as well
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I always like a myth related if you need it I'm sort of on the edge of maybe not universally recommending
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methylated bees to everyone because I have heard a small percentage of people have problems but
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comparative to the other cheap ingredients on there that's a lot safer so yeah yeah I mean if you're
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curious about whether you need methylated bees or not which frankly most people do is just get
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your genetics run it's a one-time test and then you know and then you know what you need
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so let's say someone handed you a list of 20 supplements that they're taking how do you start
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even begin to simplify it there's plenty of people taking fistful of sub fistfuls of supplements and
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like bragging about how many they take Brian Johnson, Dave Asprey, etc in the past when I had
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mold issues oh my goodness the amount I had to take in a day was insane but um essentially just
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reverse engineer the whole thing what are you actually trying to achieve with this what do you
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goal what do you what's your intention is is foundational do you have a disease that you're trying
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to prevent or rectify or do you have struggles like I don't think anyone should if they've got
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their foundations right need to take more than like four or five supplements a day and then you
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cycle them as needed so magnesium always I always take that before sleep it just quantify
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improve my sleep so I have the justification and the rationale for that one creatine I work out a
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lot I have need the mental focus so I always take that. Neutropics are an add-on they're not
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necessarily foundational although some of the botanicals certainly help with the
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neural infrastructure and the neurogenesis and the ability to retain the information that you
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learn so I consider them foundational for you know how I live my life um but then what would
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you need to take like do you have hormonal issues as a man or a woman do you need to take something
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to support hormonal clearance if there's too much estrogen or um ones that stimulate it like
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viatex if there's not enough progesterone for a woman for a man is your testosterone mo have you
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done the blood test to see that and if yes then you know consider a tribulus or a tonka dali or
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something like that and um yeah that's it's really a case of there's so much confusion that people
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like myself in the past just through shit at the wall and saw it stuck and then often you just
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end up creating like interaction problems and too much of one b vitamin or too much of a
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acetyl a acetylcholine donor and headaches you can definitely do what people do with drugs where
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you just take too many things and they kind of canna balance each other you can do that with
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supplements there's just so much more room for error versus pharmaceuticals where there's
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you know adverse reactions inside effects yeah for sure and I think one of the things and you kind
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of alluded to it is repetition of the same compound across different supplements and now all of
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a sudden you're taking way too much of you know like even a b12 can have neurological problems if
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you're overloaded but certainly the fat soluble vitamin is the ade k you can overdo those and um
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and timing as well when you take them is important like too much b12 before bed can keep someone
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up or nine they wouldn't know why I've had a couple of people in my membership community telling
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me that they've entered all of their supplements into their chat tpt and it has come back with some
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really interesting information about well you shouldn't be taking these two things at the same time
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or did you know you're actually taking you know whatever the total milligrams is of a certain
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ingredient that is overkill so I do think that you know AI love it or hate it it's here if we
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that that would be one good use of it and then there's also a company called subcoe if you heard
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of them yeah it's an app okay yeah yeah yeah they merge with another company recently I believe but
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yeah they're just like tracking of it as well and even like full script do it as well for practitioners
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who use it they can you know when you're presenting your script to patients it often can tell you
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what you're overlapping or giving two of things so there's there's a lot of ways to prevent this
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overlap but goodness if you're just shopping on Instagram or and you know just go to a supplement
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store and it's up to you then it's it's pretty hard to monitor all that I'm definitely guilty
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aceto colon being the one that I do regularly accidentally trying different pre workouts and trying
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different new tropics and brain boosters that yeah that one always sneaks up on me yeah well
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everybody loves it right all right let's let's talk about the brain a little bit when somebody says
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brain fog what what are the actual root buckets you think through first and I'm using the word
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buckets because brain fog can be due to many different things so what's your what's your list of
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things you're going to go through for those people usually when people say they have brain fog they
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say brain frog because their brains not working better so I always just have a little trick brain fog
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what's contributing to that usually there's a huge amount of stress from something that's such an
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obvious thing that I just can't not say it you know when I had brain fog brain frog the mold
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the microtoxins were getting into my brain if people aren't sleeping well that's an obvious one
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as well if they're not eating enough food if they're nutrient deficient honestly let's touch on
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that for a second nutrient deficiency with GLP1 use that's a big one that's becoming more prevalent
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not enough calories because you don't have appetite and then also not enough micro nutrients
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because you're simply not eating enough this is horrible when I'm seeing it and you know
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those epic faces is real and a lot of it's you lost weight too fast so you've got detox reaction
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but the other part of it is you just melt nourished so yeah all right you're gonna have brain fog
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from that too that's for sure the other ones can be if you're in pharmaceutical drugs for example
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SSRI's it's a big one that can sort of make or break people and more often break and then cause
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brain fog and another one for men particularly women are affected by it too is what your hormones
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are doing like estrogen and testosterone specifically to testosterone and dopamine have a really
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strong interconnected relationship so usually the higher you dopamine is the better your
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sorry the better your testosterone is the higher you dopamine is the more motivated you are the more
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you know driven and focused you can be the other ones that go into it would just be inflammation
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that's the biggest one like when you're stressed you're inflamed when you've got mold you're inflamed
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when you've got gut issues you're inflamed uh liver issues there's so many things that
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inflame us in the world it's like the inflammatory world we live in now unfortunately that um I
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hate that that's true I really wish we didn't have to fight these things all the time but just
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looking at inflammatory markers and making sure that you're not consuming excessive seed oils and
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pesticides and alcohol all of the all the things we call them basically that's sort of the root
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cause of that beyond fixing those things like if you fix them and you still got um brain fog
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of always recommended and I think I've recommended it in a previous podcast is doing the
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braverment test just to see where your neurotransmitters are at if I don't take things to help stimulate
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my brain and get it into a certain neurochemical position I am more serotonin dominant so
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everyone has like a fingerprint for what their neurotransmitters are doing at any point in time
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you do that braverment test it takes you 20 minutes and it's pretty darn accurate because I've
391
00:37:06.800 --> 00:37:11.920
compared it versus organic acids and the organic acids give you your neurotransmitter metabolites
392
00:37:11.920 --> 00:37:16.240
so kind of gives you that ratio of dopamine de serotonin and what your seed or colleague and
393
00:37:16.240 --> 00:37:22.320
your glutamine and gather all doing so that one's a cheap easy and I think free maybe not if you go
394
00:37:22.320 --> 00:37:27.440
the wrong website but uh I really get way to see where you're at with that and then if you want
395
00:37:27.440 --> 00:37:32.000
to push one of those pathways you can you can just do that based and but because you know what
396
00:37:32.000 --> 00:37:39.040
you baseline's at so yeah so then you can measure again exactly yeah and I think I mean to your
397
00:37:39.040 --> 00:37:45.840
point maybe one of the one of the tips we can give people is know your baselines like get some
398
00:37:45.840 --> 00:37:51.280
testing done before you start throwing a million things at your body all right so let's say you're
399
00:37:51.280 --> 00:37:58.800
seeing you know you're seeing all these issues in one person hair health skin thyroid brain function
400
00:37:58.880 --> 00:38:03.920
like how do you connect them into one system like how do you start to make sense of it
401
00:38:05.360 --> 00:38:11.200
well yeah you can't isolate one system and try and fix that like you mentioned all those symptoms
402
00:38:11.200 --> 00:38:16.000
my immediate thing is oh it's probably iron deficiency if your thyroid's got a problem
403
00:38:16.000 --> 00:38:21.520
brain hell you know energy and ions a huge one and honestly I think that more and more I feel
404
00:38:21.520 --> 00:38:25.840
like iron deficiency especially in women is one of the root cause drivers of thyroid issues
405
00:38:25.840 --> 00:38:31.360
thinning of hair and all that so interesting not to not to narrow in on an example like
406
00:38:31.360 --> 00:38:38.320
there's always a root cause to things and that's where I really like the accessibility of blood
407
00:38:38.320 --> 00:38:42.720
tests especially the ones where you alacard are things that are actually useful for lying on
408
00:38:42.720 --> 00:38:48.560
the standard panel from a doctor's gonna completely it's useful don't get me wrong but you
409
00:38:48.560 --> 00:38:53.600
probably got about 30 to 40 percent more tests that I ideally like to run to try and get into the
410
00:38:53.600 --> 00:39:00.320
functional to get those functional results and those functional markers to see sort of how you
411
00:39:00.320 --> 00:39:05.760
have to do things thyroid's a perfect example like TSH is pretty much all you're gonna get for free
412
00:39:05.760 --> 00:39:11.760
without trying to justify a T4 and forget about T3 and reverse T3 and then she got some issues so
413
00:39:11.760 --> 00:39:17.200
those those last two those type T3 and reverse T3 are the most important in my opinion of that
414
00:39:17.200 --> 00:39:24.560
cascade cholesterol as well like every single blood test has its nuance and there's every within
415
00:39:24.560 --> 00:39:30.320
each one of them there's an interconnected balance of all these things and that's honestly like
416
00:39:30.320 --> 00:39:35.440
I don't think we are at the stage yet where you can upload your blood test to AI and it tell you
417
00:39:35.440 --> 00:39:41.280
what a functional coach and someone with 10 five to 10 years of experience in these things
418
00:39:41.920 --> 00:39:47.920
can but it's getting a lot better that's for sure yeah just doing the testing for sure is
419
00:39:47.920 --> 00:39:53.760
is is required I think if you really want to be specific and not just be guessing in your mind
420
00:39:53.760 --> 00:39:57.840
what are the most overlooked drivers of poor focus and cognitive fatigue right now?
421
00:39:59.440 --> 00:40:07.120
dopamine deficiency I think is a big one as well as destruction from just you know email over here
422
00:40:07.200 --> 00:40:12.240
and a ping over there from Instagram and that that's all depleting dopamine and my buddy Lucas
423
00:40:12.240 --> 00:40:17.520
Owen I think you've interviewed him he talks a lot about dopamine resets and ways that you can try
424
00:40:17.520 --> 00:40:23.440
and increase your dopamine for motivation and focus I think that's a huge one that can be
425
00:40:23.440 --> 00:40:29.120
social media and technology detoxing I always you know result back to what I'm good at and that
426
00:40:29.120 --> 00:40:34.960
supplements so ingredients like triacid or urodene or urodene monophosphate have the ability to
427
00:40:34.960 --> 00:40:41.440
resensitize dopamine as well as peptides like cmax and p21 and dihexidae all can really help with
428
00:40:41.440 --> 00:40:47.520
the resensitization of the dopamine urgent neurons in the brain so you don't end up getting burnt
429
00:40:47.520 --> 00:40:52.720
out by or becoming a dopamine deficient person which you know it really sucks I've definitely been
430
00:40:52.720 --> 00:40:57.520
there with a lot of gaming I used to do when I was younger like stimulation from the game you reward
431
00:40:57.520 --> 00:41:02.560
you reward you win all the time and then you know there's so many things that can take away our
432
00:41:02.560 --> 00:41:07.760
dopamine and when that goes then the other ones just don't work as well okay so you it's
433
00:41:07.760 --> 00:41:12.880
almost like is it a depletion of dopamine or the receptors just get overworked and they just
434
00:41:12.880 --> 00:41:18.000
give up the ghost or a little bit about insulin resistance but for dopamine so desensitization
435
00:41:18.000 --> 00:41:23.280
yeah supplementation for sure supplements can do it too like I've definitely felt amazing
436
00:41:23.280 --> 00:41:27.760
drugs cocaine they all hit dopamine very well and you people who've taken those the note they
437
00:41:27.760 --> 00:41:35.360
noted any more of it caffeine same same sort of theory there but I took macuna preens al dopa
438
00:41:35.360 --> 00:41:39.840
which is the direct weakness of the dopamine I took that for ages because I felt amazing actually
439
00:41:39.840 --> 00:41:45.840
kind of felt euphoric on it and then I ate the loss of the sensitivity to it and I felt terrible
440
00:41:45.840 --> 00:41:51.840
and unmotivated and had to basically bring myself back from macuna withdrawals or not withdrawals
441
00:41:51.840 --> 00:41:59.520
but you know yeah yeah no macuna I've heard is it's and he gets thrown around as a supplement
442
00:41:59.520 --> 00:42:04.880
by people and you gotta be really careful with it because you can definitely overdo it yeah
443
00:42:04.880 --> 00:42:08.720
yeah in Australia they actually bend that you can't use it in supplements because of how much
444
00:42:08.720 --> 00:42:14.000
al dopa it has and potential interactions with schizophrenic drugs and honestly it's not the worst
445
00:42:14.000 --> 00:42:20.560
thing but I also I'm not for government saying what you can and can't take I think people can take
446
00:42:20.560 --> 00:42:24.320
it and abuse it and get in cop the ill effects without the government having to tell them they
447
00:42:24.320 --> 00:42:30.160
can't use it at all yeah well I mean you know I think part of it might be anyway I mean could
448
00:42:30.160 --> 00:42:35.200
is there a world where we can educate people enough so that they understand but it's pretty tough
449
00:42:35.200 --> 00:42:40.560
you know as you said before people can get pretty excited about stuff they hop on whatever medium
450
00:42:40.560 --> 00:42:46.720
they're on and start talking about it and you've got people not knowingly using something for too
451
00:42:46.800 --> 00:42:53.040
long or too often or too high a dose and and stuff can really start to go sideways and sometimes
452
00:42:53.040 --> 00:42:57.920
those effects don't go away that quickly where do peptides fit into brain health versus more
453
00:42:57.920 --> 00:43:03.840
traditional tools like herbs or nutrients where do you see peptides fitting in so peptides
454
00:43:03.840 --> 00:43:08.000
for brain health like peptide for gut health they're one of these tools that can achieve
455
00:43:08.000 --> 00:43:14.320
a lot more than I believe naturopathic and nutraceutical nutraceuticals can if we look at
456
00:43:14.320 --> 00:43:20.320
dihexia always compare dihexia as like the peptide equivalent of lion's main mushroom except
457
00:43:20.320 --> 00:43:27.040
it's hundreds of times more powerful for the same reason why you would take lion's main P21
458
00:43:27.040 --> 00:43:33.280
dihexia amazing seeing max is kind of like the peptide version of taking out alpha gpc you know
459
00:43:33.280 --> 00:43:38.480
there's like for like comparisons between them that's very interesting yeah yeah way way way
460
00:43:38.640 --> 00:43:44.480
better than alpha gpc as well and as well as some downstream not downstream but some really
461
00:43:44.480 --> 00:43:50.880
beneficial side effects for side effects I call them that side benefits yeah exactly yeah for
462
00:43:50.880 --> 00:43:55.040
sea max and sea length and all these ones it basically just help the infrastructure of the brain
463
00:43:55.040 --> 00:44:00.320
all the blood flow to it the synapses and all you know everything you'd want for brain health
464
00:44:00.320 --> 00:44:06.480
these peptides can do and really combat potentially combat neurodegenerative diseases versus
465
00:44:06.560 --> 00:44:12.240
taking lions main I feel like it's might give you one or two steps forward but if you you're in
466
00:44:12.240 --> 00:44:16.400
an environment and you do have a disease it might still be two step back so you kind of like
467
00:44:17.120 --> 00:44:22.400
offsetting it but not completely making inroads whereas with peptides they're strong enough as we
468
00:44:22.400 --> 00:44:27.600
know how strong peptides are they're strong enough to synergize with the nutraceuticals or the
469
00:44:27.600 --> 00:44:33.600
naturopathics and actually make progress towards that towards whatever it is you're trying to treat
470
00:44:34.240 --> 00:44:39.760
yeah and you actually do stacks cmax and clink in your in some of your formulas right
471
00:44:39.760 --> 00:44:46.320
not clink but cmax yeah oh cmax yeah cmax with p21 and dihexer in neuro origin and I wouldn't
472
00:44:46.320 --> 00:44:51.600
mind bringing out some clink as well eventually but the peptides have been really hard to source
473
00:44:51.600 --> 00:44:57.920
and do well hey folks there's a new skin care product I need to tell you about clinically
474
00:44:57.920 --> 00:45:04.240
this formula reversed up to eight years of visible aging in just 42 days it's called vampire
475
00:45:04.240 --> 00:45:11.520
exosome from young goose each bottle contains three trillion PRP derived exosomes which is about
476
00:45:11.520 --> 00:45:17.440
three times more than most serums on the market and we all know that exosomes are cellular
477
00:45:17.440 --> 00:45:24.000
messengers they are the same signals that make PRP and in office regenerative treatments so powerful
478
00:45:24.000 --> 00:45:30.640
they instruct your skin how to repair renew and produce more collagen what makes this formula even
479
00:45:30.640 --> 00:45:37.200
more advanced that is also include rejuve NAD designed to support NAD plus levels in the skin
480
00:45:37.760 --> 00:45:42.320
NAD plus is something we talk about all the time in longevity because of its role in cellular
481
00:45:42.320 --> 00:45:48.160
energy and DNA repair now in simple terms this isn't about temporary glow it's about restoring
482
00:45:48.400 --> 00:45:54.160
your skin's ability to renew itself so results build week after week instead of fading overnight
483
00:45:54.720 --> 00:46:00.720
so if you've been curious about exosome skin care this is a product setting a new standard
484
00:46:00.720 --> 00:46:06.720
you can find it at young goose.com and whether you are a new customer or an existing customer
485
00:46:06.720 --> 00:46:13.040
you get to use code NAC 10 for 10% off let's say somebody wants better focus tomorrow
486
00:46:13.680 --> 00:46:19.200
versus someone who wants better brain health 10 years from now how would you design different
487
00:46:19.200 --> 00:46:24.560
strategies for those two people. Immediate focus you can throw all of the nitripics out at the
488
00:46:24.560 --> 00:46:30.000
alpha GPC is going to help a little bit long term but short term as long as that
489
00:46:30.000 --> 00:46:35.920
colline is in your synapse it'll be working it's kind of like a caffeine thing you're not gonna
490
00:46:35.920 --> 00:46:40.320
taking caffeine by itself you know there's antioxidant anti-inflammatory benefits of the
491
00:46:41.120 --> 00:46:46.400
coffee bean that can be a benefit long term but the short term effect the half life of the
492
00:46:46.400 --> 00:46:52.400
ingredient is sort of what gives you that immediate benefit tyrosine is a precursor to dopamine
493
00:46:52.400 --> 00:46:57.920
and neurotransmitters so you can take those ones versus ones that are more of an investment
494
00:46:57.920 --> 00:47:03.120
based thing so lion's mane is more of an investment based thing because of the neurogenesis and
495
00:47:03.120 --> 00:47:07.040
there's there's certain pathways in the brain that are all to do with the architecture and the
496
00:47:07.040 --> 00:47:11.840
health of it and it doesn't just apply to the brain it applies to the whole body really like what's
497
00:47:11.840 --> 00:47:16.640
going to help the mitochondrial support ones if you're supporting mitochondria with mitochondrial
498
00:47:16.640 --> 00:47:22.960
supportive ingredients and MN or uralithin or whatever it is that is basically making the machinery
499
00:47:22.960 --> 00:47:27.840
better to produce more energy the more energy the cell has the better it can structure and function
500
00:47:27.840 --> 00:47:33.920
and then you know also contribute to the organ environment to like one cells functioning well sort
501
00:47:34.560 --> 00:47:38.880
ripple effect helps the other ones and then it's a feed forward effect that way
502
00:47:40.640 --> 00:47:45.760
for brain health the big ones that I really like are lion's mane seven eight dhf which is a
503
00:47:45.760 --> 00:47:53.600
flavonoid that's more powerful than even lion's mane wow I like ginko for blood flow go to collos
504
00:47:53.600 --> 00:47:57.680
also blood flow so improving circulations another good one that's going to help every organ in
505
00:47:57.680 --> 00:48:02.800
the body if you've got good blood flow via nitric oxide and circulatory support as well as the
506
00:48:03.920 --> 00:48:08.960
it's like you pick when I'll cook you 10 that's also fantastic for blood and cart
507
00:48:08.960 --> 00:48:14.320
cardio vascular also you asked a question earlier like how do they interplay like everything
508
00:48:14.320 --> 00:48:19.040
interplays blood flow is like very become very popular and there's lots of companies bringing out
509
00:48:19.600 --> 00:48:24.640
B-dex tracks and ones that help with nitric oxide and I'm really in support of those ones because
510
00:48:24.640 --> 00:48:29.120
blood flow is just going to ripple effect help every organ in the body we need the blood and
511
00:48:29.120 --> 00:48:33.360
the nutrients for them to work probably and that's you know we can go for brain health will
512
00:48:33.360 --> 00:48:38.880
definitely contribute to long-term yeah but the short-term ones are just quick like caffeine just
513
00:48:38.880 --> 00:48:44.000
think of them like caffeine quick it quick it just and that's great quick it's worth don't they
514
00:48:44.000 --> 00:48:49.680
they do but you I think to me you want to do both it's great to do the immediate stuff of course
515
00:48:49.680 --> 00:48:54.800
everybody wants their brain firing but you want to do it in a way that's a think of it as an
516
00:48:54.800 --> 00:49:00.560
investment right like what you're doing for the short-term and I and maybe this is a good question
517
00:49:00.560 --> 00:49:05.200
like are there things that people are doing for short-term gains that might be compromising their
518
00:49:05.200 --> 00:49:13.280
long-term brain health it's a good question I'm just trying to think about what people are doing
519
00:49:14.160 --> 00:49:20.240
yes definitely I think that we if we look to the stimulant space in pre workouts people
520
00:49:20.240 --> 00:49:23.920
depend on caffeine and then they need more and more and more and then they actually
521
00:49:23.920 --> 00:49:28.480
doesn't necessarily hurt their brain health directly but then they'll end up being burnt out
522
00:49:28.480 --> 00:49:32.480
their adrenals aren't functioning right and then when your adrenals go and then your energy
523
00:49:32.480 --> 00:49:38.160
goes to shit then all of the positive habits like exercise and doing all of the things that
524
00:49:38.160 --> 00:49:42.160
contribute to overall health that can really fall off so you don't want to do things that can
525
00:49:42.160 --> 00:49:47.760
potentiate or bring on burnout and nothing that's going to compromise your thyroid to and that
526
00:49:47.760 --> 00:49:53.520
can be prolonged key to genetic diets for example that can be fasting for a week you know every
527
00:49:53.520 --> 00:49:57.280
every month those sort of things that put your body into hibernation mode and shut down your
528
00:49:57.280 --> 00:50:02.480
thyroid like interventionally short-term yes that's fine but not long-term I definitely burnt
529
00:50:02.480 --> 00:50:07.840
myself out with doing keto and carnivore too long I you know make mistakes and then I learned
530
00:50:07.840 --> 00:50:13.280
from them and people I think some can thrive on it but I honestly don't think that would be
531
00:50:13.280 --> 00:50:19.840
beneficial to do for a long period of time and could hurt brain health indirectly yeah well
532
00:50:19.840 --> 00:50:24.560
I think I think that it's it's again it's one of those things it depends what your goals are
533
00:50:24.560 --> 00:50:29.440
right if cancer is a real issue for you maybe that a little more fasting is right but if you're
534
00:50:29.440 --> 00:50:34.960
trying to build muscle for longevity too much fasting is not going to serve those goals
535
00:50:34.960 --> 00:50:39.120
on that query it's like short-term versus long-term well if you've got cancer then the short-term
536
00:50:39.120 --> 00:50:44.720
is the immediate focus and the long-term is like our high will let's deal with it later you do
537
00:50:44.720 --> 00:50:48.480
that right yeah yeah if your thyroid does to go down but you bait and you can say you can fix
538
00:50:48.480 --> 00:50:54.240
the thyroid but you don't want to have to fix the other one yeah yeah a hundred a hundred percent
539
00:50:54.240 --> 00:50:58.880
all right so let's go and move into organs and systems when you zoom out which organ systems do you
540
00:50:58.880 --> 00:51:06.320
think are the higher give us the highest leverage for longevity okay so muscles always the one
541
00:51:06.320 --> 00:51:11.360
that people have to talk about yeah yeah sing into the choir right now like muscle health there's
542
00:51:11.360 --> 00:51:21.840
peptides that are actually coming into the fray now for muscle support is that Luca talking about
543
00:51:21.840 --> 00:51:30.960
TB4 yeah we're not even editing this out you guys how old is Luca Luca is three and a half and
544
00:51:30.960 --> 00:51:35.920
he's a little you know I probably shouldn't admit this he's a peptide baby I'm saying around
545
00:51:35.920 --> 00:51:42.320
like taken some products during her pregnancy and yeah he's three and a half is the apple of my
546
00:51:42.320 --> 00:51:47.440
and he's he's awesome and he also likes his own card thing evidently and he's super cute so you
547
00:51:47.440 --> 00:51:52.880
started with muscle which you know it's the darling of the organ systems for longevity these days
548
00:51:52.880 --> 00:51:59.440
because of all of the benefits and frankly even for the brain what else so how we can help support
549
00:51:59.440 --> 00:52:07.520
the muscle or finish that loop is hmb um lucine you know all these antibiotics um amino acids having
550
00:52:07.520 --> 00:52:13.120
a full spectrum of amino acids is a great way of doing it uh peptis strong peptide dilucines
551
00:52:13.120 --> 00:52:17.760
another one that these are too fully compliant you know you can buy them anywhere peptides
552
00:52:17.760 --> 00:52:22.800
that are not like the other peptides but they're still beneficial that's for sure ones that uh in
553
00:52:22.800 --> 00:52:28.720
like dilucine is just too lucine amino acids put together to make a peptide so it fits under
554
00:52:28.880 --> 00:52:33.520
that category but it's not like the ones that have these um what am I trying to say these
555
00:52:33.520 --> 00:52:39.440
transcription regulatory issues yeah exactly they don't have the regulatory issues but then they
556
00:52:39.440 --> 00:52:45.040
also aren't going to work on multiple multiple different things like a BPC will there's really
557
00:52:45.040 --> 00:52:49.280
specifically for one thing the other thing for longevity that I mentioned earlier was the blood flow
558
00:52:49.280 --> 00:52:54.080
making sure you've got the blood flow and then the bigger one that feeds in concurrently with
559
00:52:54.080 --> 00:52:59.120
blood flow is blood sugar balance so it can be something that can help restore that
560
00:52:59.120 --> 00:53:03.680
anything you do like the muscle and exercise is going to regulate your blood sugars but um
561
00:53:03.680 --> 00:53:08.400
prolonged blood sugar issues like diabetes, circulatory issues all come from from uh
562
00:53:09.520 --> 00:53:16.560
dysregulated insulin and um fasting blood sugars or fasting and fed blood sugars
563
00:53:16.560 --> 00:53:21.040
trying to normalize that blood sugar curve throughout the day and have it not go on massive
564
00:53:21.200 --> 00:53:27.120
excursions up and downs is definitely a beneficial thing for longevity. Yeah I would agree with that for
565
00:53:27.120 --> 00:53:31.600
sure and do you have certain compounds that you think are particularly helpful in helping people
566
00:53:31.600 --> 00:53:37.040
in that world? Yeah um I used to use metformin and I've completely moved away from talking about that
567
00:53:37.040 --> 00:53:41.680
and using it because there are naturopathic ingredients that are better that I think dihydro
568
00:53:41.680 --> 00:53:48.320
burberine would be a candidate as a replacement or an alternative to that one regular burberine
569
00:53:48.320 --> 00:53:54.400
is good too but here's a pharmacokinetic fun fact about regular burberine you need about 500
570
00:53:54.400 --> 00:53:59.360
milligrams to a thousand milligrams of it and of that only about one percent of it of it absorbs
571
00:53:59.360 --> 00:54:04.560
so it's terrible absorption and can cause a lot of GI upset because 99% of it is hanging around
572
00:54:04.560 --> 00:54:11.040
in your gut and then modulating um microbiome and you can have a lot of um die off reaction
573
00:54:11.040 --> 00:54:17.200
potentially from burberine and burberines often use for candida and um intestinal overgrowth because
574
00:54:17.280 --> 00:54:24.960
of that pharmacokinetic fact that it does have anti um microbial effects and if you're taking it
575
00:54:24.960 --> 00:54:29.600
for the purposes of blood sugar regulation you need to be aware that that 1% is going to help so
576
00:54:29.600 --> 00:54:34.480
taking burberine will help too but I'm modified to metabolite a burberine dihydro burberine
577
00:54:35.200 --> 00:54:40.400
absorbs about I think like 50 times better than regular burberine so you don't need to do mount
578
00:54:40.960 --> 00:54:44.800
and it's going to get into circulation so you don't have to worry about the gut issues
579
00:54:44.800 --> 00:54:50.400
and then it's going to have that you know blood sugar regulating um it drops it yeah it just normalizes
580
00:54:50.400 --> 00:54:56.080
blood sugar and works similar to metformin uh other ones grains of paradise is awesome for that one
581
00:54:56.080 --> 00:55:02.880
too um what's the our friend Sean Wells is alive and well in this podcast both of those are uh
582
00:55:02.880 --> 00:55:09.040
dilucine dihydro burberine and grains of paradise those are all Sean Wells molecules
583
00:55:09.040 --> 00:55:11.040
all right I'll get away from Sean chromium
584
00:55:11.120 --> 00:55:16.080
yeah well I actually I think it's great I mean he's he's a great resource in the industry right
585
00:55:16.720 --> 00:55:22.080
chromium b1 they're also beneficial as well and yeah there's there's plenty of other things like
586
00:55:22.080 --> 00:55:28.480
OVA is another one that's a fat burner and helps blood sugar and yeah there's there's an absolute
587
00:55:28.480 --> 00:55:33.200
treasure trove of ingredients that you can use for blood sugar control but when I focus in on the
588
00:55:33.200 --> 00:55:37.840
most hard hitters it's the dihydro burberine for sure the relationship between liver function
589
00:55:37.920 --> 00:55:43.840
hormones and energy from a formulation perspective I'm making it work for today my friend
590
00:55:46.320 --> 00:55:51.920
the relationship between liver hormones and energy right okay that's a big one I it actually
591
00:55:51.920 --> 00:55:56.240
tell people to go back and listen to our liver episode I think we yeah that was a good one
592
00:55:56.240 --> 00:56:01.280
yeah you can't bother it I'll just do it really quickly yeah um liver metabolizes all your hormones
593
00:56:01.280 --> 00:56:06.320
basically it is the clearance house for them estrogen testosterone progesterone cortisol all
594
00:56:06.320 --> 00:56:13.120
them for processed and removed by the liver you need to support liver health to support healthy
595
00:56:13.120 --> 00:56:19.600
hormone clearance and hormones like thyroid for example is converted to T3 primarily by the liver
596
00:56:19.600 --> 00:56:24.400
so if you've got liver congestion if you're a male who's been in the gyms taking exandrolone or
597
00:56:24.400 --> 00:56:29.520
some testosterone thing that's you know all issues with the liver or if you're like me living in
598
00:56:29.520 --> 00:56:33.760
mold and had chronically elevated liver enzymes because of that information then you're not
599
00:56:33.920 --> 00:56:36.880
going to be processing your hormones properly because the liver's overburdened
600
00:56:38.080 --> 00:56:43.360
bile often feeds in hand in hand with the liver and if you're not bile is one of the primary ways
601
00:56:43.360 --> 00:56:49.600
that you clear your hormones so if you want good hormonal health you pretty much as a as a foundation
602
00:56:49.600 --> 00:56:56.400
need good liver health as well um it's not I don't think it's the most common problem that people
603
00:56:56.400 --> 00:57:01.920
will have from a genetic perspective um but it definitely you know how we clear hormones without
604
00:57:02.080 --> 00:57:06.560
like what our methylation was our comps doing and what you know all that conjugate how they were
605
00:57:06.560 --> 00:57:11.440
but how does our body conjugate our hormones and remove them properly that's a huge thing that can
606
00:57:12.000 --> 00:57:16.560
upstream affect what our hormones are actually doing in circulation because of the feedback
607
00:57:16.560 --> 00:57:22.080
loops of the hormones yeah and also gut health feeds into that too because when we clear our hormones
608
00:57:22.080 --> 00:57:28.320
they can end up recirculating if we've got bacterial overgrowth or um you know we deep
609
00:57:28.320 --> 00:57:35.440
deep glucoronidase enzymes in our gut from candida can recirculate a lot of the estridans as well
610
00:57:36.480 --> 00:57:40.800
and then how does that feed into energy or thyroid implicitly linked to energy and how much
611
00:57:40.800 --> 00:57:46.240
how well you feel um even cortisol how that's clear it's affected by the liver too so
612
00:57:46.240 --> 00:57:52.000
you might have a broken diurnal cortisol rhythm because of your body's inability to clear it
613
00:57:52.000 --> 00:57:57.440
or you know overburdening of the enzymes that sort of break it down or make it go back and forward
614
00:57:57.440 --> 00:58:02.960
between um the cortisol and cortisol too if you take care of your liver and as you said like go
615
00:58:02.960 --> 00:58:09.520
back to that liver episode guys because it's at the center of of hormones and energy quite frankly
616
00:58:09.520 --> 00:58:16.800
if your liver is congested nothing's gonna work like it just it's you know we think of so many
617
00:58:16.800 --> 00:58:22.000
other organs as being the most important organ but that organ it's a it's a heavy lifter
618
00:58:22.960 --> 00:58:27.920
yeah absolutely and often when it's not lifting and the skin and the kidneys are the ones that
619
00:58:27.920 --> 00:58:32.080
pick up the slack so if you have those issues then look to live a first and then if your liver's
620
00:58:32.080 --> 00:58:35.920
not resolving look to gut because the gut and the liver access is another one that's huge
621
00:58:36.480 --> 00:58:41.840
yeah we need to consider yeah and it's funny you say that because you know for even for teenagers
622
00:58:41.840 --> 00:58:47.440
who are dealing with skin issues with acne very few people will say take care of your liver
623
00:58:47.440 --> 00:58:51.520
and delivers busy at that point there's a lot of hormones they're not eating as well as they
624
00:58:51.520 --> 00:58:56.640
should be sometimes taking care of liver and gut health can be the best rather than slapping
625
00:58:56.640 --> 00:59:01.840
something on top your skin can actually be much more effective I'm definitely a fan of skincare
626
00:59:01.840 --> 00:59:06.000
now that we've been trying to bring out skincare for three years but at the same time I'm always
627
00:59:06.000 --> 00:59:11.840
root cause like if your skin's bad you know the the external um approach is not gonna you know
628
00:59:11.840 --> 00:59:15.760
the little long term results and you just be fighting at the whole time versus root cause
629
00:59:15.760 --> 00:59:21.840
yeah start from the inside all right so hard health how do you approach it differently from a
630
00:59:21.840 --> 00:59:28.560
formulation perspective compared to conventional advice heart health all right so blood flow is how
631
00:59:28.560 --> 00:59:33.760
I look at that one um naturopathically I don't I really really really really really really like
632
00:59:33.760 --> 00:59:39.280
TB4 fragments and TB500 for heart health I think that's probably it's most that's probably
633
00:59:39.280 --> 00:59:43.600
the most powerful of all of the peptides for heart health you can correct me if you have a different
634
00:59:43.600 --> 00:59:48.880
opinion but in my opinion those fragments um one of the two I've forgotten which one um is really
635
00:59:48.880 --> 00:59:56.560
good as an anti-fibroidy yeah the heart bioregulators I remember the name of all and there's too many
636
00:59:56.560 --> 01:00:01.040
and they all sound the same this is a heart bioregulator hearty agent hearty agent not
637
01:00:01.040 --> 01:00:06.160
at the heart killer killer heart which is the same as cardiogen only it's the natural versus the
638
01:00:06.160 --> 01:00:12.560
synthetic I didn't need to remember I got you here to help me all good so bioregulators yes
639
01:00:13.280 --> 01:00:20.080
yeah um I I believe naturopathically some of the most powerful things for cardiovascular health
640
01:00:20.080 --> 01:00:25.440
you're gonna look at things like nato kinase and cerepeptase yeah fantastic anti-fibrogenic
641
01:00:26.400 --> 01:00:31.920
enzymes they break down fibrin and they also have the ability to sort of dissolve away any sort of
642
01:00:31.920 --> 01:00:37.760
plaques and any um build-ups of things you don't want in circulation and I'd say heart attacks
643
01:00:37.760 --> 01:00:42.720
is essentially just clots and you know problems that are a circulatory thing that sort of manifest
644
01:00:42.720 --> 01:00:47.680
and find their way into the heart and same with stroke so if we're taking a lot of there's been a
645
01:00:47.680 --> 01:00:52.640
lot of study around low-dose aspirin and I'm not recommending that I'm recommending instead
646
01:00:52.640 --> 01:00:58.000
low-dose nato kinase um for the same benefit of aspirin thins of blood and that's why it's
647
01:00:58.000 --> 01:01:04.160
beneficial right so if we can take something like a nato kinase for example um it can really help
648
01:01:04.160 --> 01:01:09.680
with you know that blood flow purely from the thinning effect it has white willow bark is the
649
01:01:09.680 --> 01:01:14.800
natural alternative to aspirin and you're going to get this with salison from that as well and
650
01:01:14.800 --> 01:01:21.280
that can be that can be beneficial for thinning the blood astrics it's got that inverse you curve
651
01:01:21.280 --> 01:01:24.960
as well too much of that tooth in a blood you get a paper cut and then you bleed for 20 minutes
652
01:01:24.960 --> 01:01:30.800
you probably can take it easy on those ones um but yeah for heart health I also look towards
653
01:01:30.800 --> 01:01:36.160
ubiquinol koki-ten yeah that's really implicitly linked in mitochondria after when your heart
654
01:01:36.160 --> 01:01:40.720
got a very high density of mitochondria it's probably one of the most I think it is the most
655
01:01:40.720 --> 01:01:45.680
dense organ for mitochondria so anything that's going to support mitochondria will help your heart
656
01:01:45.680 --> 01:01:49.920
and I think yoga months another one that's really good like a cut of your protective and circulatory
657
01:01:49.920 --> 01:01:58.480
supporting one yeah yeah beautiful all right so in your opinion what's one system in the body
658
01:01:58.480 --> 01:02:03.760
that you think is quietly driving a lot of dysfunction but doesn't get nearly enough attention
659
01:02:05.040 --> 01:02:14.000
what are we overlooking it's a good one um look for my personal experience lung health and that one
660
01:02:14.000 --> 01:02:19.680
is a hard one effect now oxygen and I was talking about blood flow but upstream the blood flow
661
01:02:19.680 --> 01:02:25.120
where does it come from your lungs and your your ability to breathe properly I think a lot of the
662
01:02:25.120 --> 01:02:30.880
winds are for improving cardiovascular health and lung health come from doing exercise doing breath
663
01:02:30.880 --> 01:02:36.240
training uh it's the pentagre breathing I've forgotten the guy's name but he has the oxygen
664
01:02:36.240 --> 01:02:42.800
advantage book all that sort of stuff as well uh James nester is that James nester or the other guy
665
01:02:43.520 --> 01:02:50.480
or patric patric yeah patric yeah training your breath and making sure you're not shallow breathing
666
01:02:50.480 --> 01:02:58.080
nasal strips um mouth tape uh and then honestly my biggest lung issue came from the molds I had
667
01:02:58.080 --> 01:03:02.880
like lung issues because of the mold and a lot of people do as well um but yeah lung health is a
668
01:03:02.880 --> 01:03:07.600
huge one that I think is upstream to all of this oxygenation we're looking for yeah and
669
01:03:07.600 --> 01:03:11.760
we still improve it there's not too many supplements there's a few that I'm been looking at I'm
670
01:03:11.760 --> 01:03:18.480
going to be bringing out quarter seps is fantastic for anything that improves like athletic VO2 max
671
01:03:18.480 --> 01:03:22.960
yeah high hypothesized what it's going to help your lungs if it's helping with that
672
01:03:22.960 --> 01:03:27.920
be it from circulation or from improving lung health so that's um a product I'm bringing out soon
673
01:03:27.920 --> 01:03:33.200
called VO2 max with quarter seps a really good quarter sepses extract as well as a patented
674
01:03:33.200 --> 01:03:40.480
ingredient called oxygen which um helps with oxygen delivery so yeah there's a non blood flow
675
01:03:40.480 --> 01:03:45.920
enhancing ways of improving you know your circulatory and lung health those are some big ones that
676
01:03:45.920 --> 01:03:51.200
I really um think upstream quite a quite a few systems well it's interesting you're bringing up
677
01:03:51.200 --> 01:03:56.240
quarter seps for lung because the first time I learned about quarter seps was my husband was going
678
01:03:56.240 --> 01:04:01.760
to climb Kilimanjaro and I was looking for is there anything in this supplement world that can
679
01:04:01.760 --> 01:04:08.640
help with altitude high altitude training or function and it turns out quarter seps is one of the
680
01:04:08.720 --> 01:04:13.120
is one of those things that can actually help so there you go and I love that you brought
681
01:04:13.120 --> 01:04:18.240
up lungs because nobody talks about lungs when do you reach for peptides over herbs and when do
682
01:04:18.240 --> 01:04:27.040
you avoid them completely oh good one um for testosterone I don't see any peptides that do is
683
01:04:27.040 --> 01:04:32.400
what do a good a job of increasing that as herbs yeah I think we'll outperform them um everyone
684
01:04:32.400 --> 01:04:36.240
talks about are you going to take tessamoraline or kiss peptine and this will help with that will
685
01:04:36.240 --> 01:04:42.320
help and I just don't ever I've never seen a compelling blood panel to say that peptides help with
686
01:04:42.320 --> 01:04:49.200
hormones yeah well directly anyway um women's hormones men's hormones I think it's kind of a
687
01:04:49.200 --> 01:04:54.640
relevant I don't see peptides working there I always will look for peptides for gut health because
688
01:04:54.640 --> 01:05:00.800
I have used them for years and I know how well they work and how fast yeah um it's the speed really
689
01:05:01.600 --> 01:05:07.120
yeah yeah anything instant far instant fast results so for a brain formula I want it to work now
690
01:05:07.120 --> 01:05:12.720
today when I take it so I'll reach for them uh interchangeably with the new new tropic
691
01:05:12.720 --> 01:05:16.640
naturopathic stuff so it's kind of like like for like you can take one you take the other you can
692
01:05:16.640 --> 01:05:20.480
take them together there's no sort of nuance but for gut health like if I was to just take one
693
01:05:20.480 --> 01:05:26.480
ingredient for it it'd be BPC so there's that case versus glutamine it's not going to do much um for
694
01:05:26.480 --> 01:05:31.280
you to be honest it'll help but over a couple months sort of thing it takes time people get
695
01:05:31.280 --> 01:05:36.880
uh they people get frustrated before they really get the results yeah and then back to herbs too
696
01:05:36.880 --> 01:05:41.520
I always go for herbs it's still a hormone for cortisol burn out herbs in vitamins are going to
697
01:05:41.520 --> 01:05:48.800
work a lot better for burnout for stress management um so like a ashwagandha or a holy basil or
698
01:05:48.800 --> 01:05:55.280
a rodeo much better for modulating your stress and giving you sort of energy yeah yeah those are
699
01:05:55.360 --> 01:05:59.200
sort of some use cases for it we could probably go through every system and say would you take a
700
01:05:59.200 --> 01:06:05.360
peptide for brain or a rodeo it'll be lungs and I'll be like yes to know maybe yeah is there do you
701
01:06:05.360 --> 01:06:11.120
ever avoid them completely peptides are there any situations where you're just like yeah no I'm
702
01:06:11.120 --> 01:06:16.160
avoiding GLP ones because I'm stubborn and I would like to find naturopathic ways in neutral
703
01:06:16.160 --> 01:06:20.240
natural way to try and rival them and I'm playing around with multiple different
704
01:06:20.800 --> 01:06:24.400
delivery mechanisms of different metabolites and this and that and
705
01:06:25.120 --> 01:06:30.080
all right I'm not getting close but it's maybe if we can get a third as effective and I'll be happy
706
01:06:30.080 --> 01:06:35.360
with that but yeah I'm not doing GLP ones for many reasons even though they they are an amazing
707
01:06:35.360 --> 01:06:40.000
shortcut and certainly work and everyone knows it because you know just look at like
708
01:06:40.000 --> 01:06:43.680
Debbie Moore for example how strong they can be when they're overused and you know
709
01:06:43.680 --> 01:06:48.000
these are stories from people who've done a mile and you know Tina Moore had had to help
710
01:06:48.000 --> 01:06:52.160
these educating people properly and how to dose them too so I just haven't personally reached
711
01:06:52.160 --> 01:06:57.760
for them because I'm not at the stage where I need to try all these other things first I don't
712
01:06:57.760 --> 01:07:03.280
need the confounder of oh my you know my natural GLP one worked really well I took for a
713
01:07:03.280 --> 01:07:11.600
separate time too but yeah yeah no I mean listen if you don't need them why why even go there I mean
714
01:07:11.600 --> 01:07:16.960
you know there is a storyline that they may be a very good tool for longevity down the road but
715
01:07:17.040 --> 01:07:23.600
I don't believe that unless you have like dysregulated metabolic markers or you have that need so
716
01:07:25.040 --> 01:07:30.800
you know a healthy balance system will take it over something like that any day it's just that so
717
01:07:30.800 --> 01:07:36.640
few people have that healthy balance system right now um so which leads to our next question you
718
01:07:36.640 --> 01:07:41.280
know do you think we're over relying on peptides as a shortcut or do you think they're genuinely
719
01:07:41.280 --> 01:07:48.560
a next evolution in health optimization uh over relying on them probably I will we become more
720
01:07:48.560 --> 01:07:54.720
relying on them definitely especially now they've recategorized p-cost to p-moss that now opens up
721
01:07:55.440 --> 01:08:01.360
a PCOS yeah yeah PCOS is now I've forgotten the exact way they've done it but they're basically
722
01:08:01.360 --> 01:08:06.560
described as a metabolic problem rather than a ovarian problem and interestingly a friend of mine
723
01:08:06.800 --> 01:08:11.760
shared this it's because now that now that they've made it a metabolic thing they will be able to
724
01:08:11.760 --> 01:08:16.960
probably prescribe the GLP runs for treatment of that which opens up a whole new market so we
725
01:08:16.960 --> 01:08:23.200
will be using them a lot more but I am not in I'm not against the use of them um because they are
726
01:08:23.200 --> 01:08:28.320
going to shortcut results and then if you come off of them heck I'll take that 50% reduction in
727
01:08:28.320 --> 01:08:33.840
the time it takes and the effort it takes to you know rectify a problem um and they provided you
728
01:08:33.840 --> 01:08:38.080
you can't get off them this is this is the new ones to it is you need to be able to do it properly
729
01:08:38.080 --> 01:08:41.680
not help yourself when you're on them and then be able to get off them and live your life without
730
01:08:41.680 --> 01:08:45.920
them that's that's the overall alliance problem that I see and it will it will be a problem
731
01:08:46.560 --> 01:08:53.520
yeah for sure so what's your hierarchy if someone had to choose between lifestyle supplements
732
01:08:53.520 --> 01:08:59.760
and biohacks how do you prioritize between those three lifestyle supplements and biohacks like
733
01:08:59.760 --> 01:09:04.080
a lifestyle biohacks and then supplements in that like descending order the supplements supplement
734
01:09:04.080 --> 01:09:12.000
the other things the other things feed into foundations the foundations like lifestyle if you're
735
01:09:12.000 --> 01:09:17.040
not saving properly relationships all of the things we we we talk about it ad nauseam that's
736
01:09:17.040 --> 01:09:24.560
definitely the the order to it um my my hierarchy of healing is there's foundations there's digestion
737
01:09:24.640 --> 01:09:29.840
and then there's detoxification it's like top three immune system number four hormones and then
738
01:09:29.840 --> 01:09:35.200
all of the biohacking optimizing your lipids dihexas all those other things are at the bottom of it
739
01:09:35.200 --> 01:09:40.160
because you don't need them to function really well but when you're already functioning really well
740
01:09:40.160 --> 01:09:44.960
and you just like come on and then just want to keep push it and see how good it can get that's
741
01:09:44.960 --> 01:09:51.440
when they come in yeah yeah I love that all right what's one simple intervention that consistently
742
01:09:51.440 --> 01:09:56.640
outperforms more complex stacks botanical indigo naturalis that was annoying to hear and all
743
01:09:57.200 --> 01:10:04.000
what's it called botanical what botanical GI IBD supportive one the indigo naturalis
744
01:10:04.480 --> 01:10:10.080
indigo naturalis yeah yeah that one's really good um it does have long term use problems so
745
01:10:10.080 --> 01:10:15.040
that's like a quick interventional thing that does outperform a lot of peptides which is pretty
746
01:10:15.440 --> 01:10:23.920
um ingredients themselves I've really am very strong on this new ingredient that's already in
747
01:10:23.920 --> 01:10:27.680
existence but it's not been done properly and we're working on it so I'll sneak peak what we're
748
01:10:27.680 --> 01:10:33.520
working on it's called a moden yeah yeah a moden clears cortisol to cortisol and really strongly
749
01:10:33.520 --> 01:10:43.920
it up regulates the enzyme 11 beta hydroxy something cortisol anyway yeah so it lowers cortisol
750
01:10:44.000 --> 01:10:49.120
it lowers cortisol so powerfully but the biggest limitation to it is the bioavailability being
751
01:10:49.120 --> 01:10:54.560
like 0.1% and then being cleared out by your kidney super fast so if anyone ever tries a moden
752
01:10:54.560 --> 01:10:59.600
they will notice their p looks bright orange like a blood orange because that's the moden itself
753
01:10:59.600 --> 01:11:05.120
that's the flow they um the constituents of the moden being cleared by the kidneys but it
754
01:11:05.120 --> 01:11:10.080
definitely definitely is um a moden and camp for all of the two really promising ones that I'm
755
01:11:10.160 --> 01:11:14.400
looking up for stress management that outperform all the other stress management farmers who
756
01:11:14.400 --> 01:11:20.400
are like with the anias and alphanines all right quick fire this is a game of if this than that
757
01:11:20.960 --> 01:11:31.520
okay so if someone has constant brain fog then if brain fog then alpha g pc and lion's main all
758
01:11:31.520 --> 01:11:38.080
lions main try one or the other or and even higher and probably more beneficial for everything
759
01:11:38.080 --> 01:11:41.840
would be try creatine first before those other creatine because it doesn't help your brain fog it
760
01:11:41.840 --> 01:11:46.080
will help other things that's for sure well and your creatine has so much stuff built into it
761
01:11:46.080 --> 01:11:51.360
that I think that you know you're gonna hit the mark somewhere if someone has low energy but normal
762
01:11:51.360 --> 01:12:00.480
labs then low energy and but normal labs then look to thyroid normal labs would imply normal
763
01:12:00.880 --> 01:12:07.040
yeah yeah I don't know many people who have normal labs that have low energy to be fair so
764
01:12:07.040 --> 01:12:15.040
I would definitely dig dig deeper into thyroid and then I would also look at your organic acids test
765
01:12:15.040 --> 01:12:19.440
do one of them that's not a normal test see where you might a condry or your crypt cycle might be
766
01:12:19.440 --> 01:12:26.400
broken from that cool if someone wants better skin and hair first up a g h k g h k g h k
767
01:12:26.480 --> 01:12:29.920
if someone is dealing with joint pain
768
01:12:31.600 --> 01:12:38.720
sister squadrangularis that one's amazing it's one I actually added to Wolverine because that
769
01:12:38.720 --> 01:12:44.320
was one of those annoying little herbs that was getting kind of comparative compared to like
770
01:12:44.320 --> 01:12:49.520
hyaluronic acid and bpc for how much it helped with recovery and joint pain the other one
771
01:12:49.520 --> 01:12:54.720
that I really like for rheumatoid arthritis is devil's claw that's an amazing herb botanical
772
01:12:54.720 --> 01:13:03.440
for rheumatoid pain and hyaluronic acid too for the lubrication that's awesome stuff
773
01:13:03.440 --> 01:13:07.360
beautiful if someone's overwhelmed with supplements what's your advice to them
774
01:13:08.720 --> 01:13:17.840
just take 50 at once just don't count yeah well just don't count exactly if they're overwhelmed by
775
01:13:17.840 --> 01:13:24.880
it honestly you said it just run through your what you're taking through chat GPT and just say
776
01:13:24.880 --> 01:13:29.840
look I'm there's too many things help me break it down or in lieu of chat GPT and probably a
777
01:13:29.840 --> 01:13:33.840
better option is work with someone who knows what they're doing it's yeah it's so hard to figure it
778
01:13:33.840 --> 01:13:38.240
out yourself I've figured out a lot but I've also worked with a lot of people prior who've helped
779
01:13:38.240 --> 01:13:42.000
me figure it out so there's no shame in asking for help with this stuff it's it's complicated it's
780
01:13:42.480 --> 01:13:47.840
so beautiful if someone wants to invest in one high impact upgrade for their health this year
781
01:13:47.840 --> 01:13:55.200
what would you suggest the just one one money no factor I get a HBOT hey hyperbaric oxygen
782
01:13:55.200 --> 01:14:01.920
I'm so bullish on HBOT at the moment I love them my local gyms just got one so I'm going to be
783
01:14:01.920 --> 01:14:06.320
investing in doing hyperbaric oxygen and you've interviewed scotcher for people who want to
784
01:14:06.320 --> 01:14:10.720
listen more about that I won't even try and attempt to give you one tenth of the information he's
785
01:14:10.720 --> 01:14:16.480
capable of who's there oh scotcher yeah no he's amazing what does the future formulation look
786
01:14:16.480 --> 01:14:21.760
like in the next five to ten years are you working on something that is super exciting too you're
787
01:14:21.760 --> 01:14:26.080
always working on something exciting but working on too many things that that's why I'm working on
788
01:14:26.080 --> 01:14:34.080
a stress formula the future of supplements I believe it will be led by brands like mine and there
789
01:14:34.080 --> 01:14:40.000
are plenty of other ones out there like phone who are doing and spending the money to test their
790
01:14:40.000 --> 01:14:46.160
products and to prove them and our transparent with what they put in it there's too many too many too
791
01:14:46.160 --> 01:14:53.040
many too many brands out there who are not do not care do not test do not prove the purity and
792
01:14:53.040 --> 01:14:57.840
luckily Amazon has started to be aware of that they really copped some bad press over the last
793
01:14:57.840 --> 01:15:02.320
few years for basically buying supplements on there and now that we're getting level up on
794
01:15:02.320 --> 01:15:06.720
now I'm like wow how did all this stuff get past this is really hard to pass these hurdles and
795
01:15:06.720 --> 01:15:12.320
we're already doing very high very high amounts of testing but it's come to the point where you
796
01:15:12.320 --> 01:15:16.960
just there was no hurdle for it you could just sell on it so now we have to test every single
797
01:15:16.960 --> 01:15:22.240
ingredient in every formula get full certificates of analysis like we do a lot of that anyway but for
798
01:15:22.240 --> 01:15:28.480
every ingredient it's not something we've necessarily have to do every time so it's become a lot
799
01:15:28.480 --> 01:15:33.040
more expensive as well which is an unfortunate reality we already expensive and then we've got to
800
01:15:33.040 --> 01:15:39.760
spend like 20,000 dollars testing each product so that's going to be a barrier to it and as
801
01:15:39.760 --> 01:15:47.520
the supplement industry changes I think there'll be a huge discrepancy between the top-end
802
01:15:47.520 --> 01:15:53.200
businesses who've kind of done all of that pre all that expensive work for a long time and then
803
01:15:53.200 --> 01:15:57.520
always fly by night ones who come in and like oh you know it's a billion dollar industry I'm just
804
01:15:57.520 --> 01:16:01.760
going to start making stuff and then they don't realize all of the requirements to it and I think
805
01:16:01.760 --> 01:16:05.440
those requirements are only going to grow not necessarily from government but from these
806
01:16:06.400 --> 01:16:11.120
essential mediums for sale of them so what are you working on that's really exciting you're
807
01:16:11.120 --> 01:16:16.640
right now I'm working on might not excite your audience but I work out a lot I've been work I had
808
01:16:16.640 --> 01:16:21.120
a pre-workout and it was disgusting yeah you ditched it yeah ditched it I've been working on that
809
01:16:21.120 --> 01:16:27.440
for about a year now reformulating it using every single patented material that I possibly could
810
01:16:27.440 --> 01:16:32.000
testing everything and just making the best pre-workout that you can take as a daily even if you
811
01:16:32.000 --> 01:16:39.680
don't work out yeah and what else am I working on a b a b vitamin a daily b with all of the
812
01:16:39.680 --> 01:16:45.040
essentials like the ubiquinoles the coq tens and all of the minerals just something that people
813
01:16:45.040 --> 01:16:49.200
can take daily is like that if you were to take only one thing I'd make it that one you know I
814
01:16:49.200 --> 01:16:53.520
don't like milking formulas and products that people have to take every day but if you're going
815
01:16:53.680 --> 01:16:59.360
if you want to then that one's probably the real foundational one and beyond that I was another 20
816
01:16:59.360 --> 01:17:04.080
or so coming out all right we don't have to list them all you got to keep some stuff secret
817
01:17:04.080 --> 01:17:08.320
are we heading toward a world where people self-experiment too much without understanding the
818
01:17:08.320 --> 01:17:15.200
fundamentals yeah probably TLP ones are definitely evidence of that and I think they're a gateway
819
01:17:15.200 --> 01:17:18.400
drug to the other ones to be honest if people have already gotten over the barrier to entry of
820
01:17:18.400 --> 01:17:24.000
injecting with JLP is more likely to try all the other ones so definitely yeah it's getting there
821
01:17:24.640 --> 01:17:28.560
what's one trend in the health space that excites you and one that concerns you
822
01:17:30.560 --> 01:17:35.200
I'm really liking the extreme influences are starting to be less extreme Brian Johnson's
823
01:17:35.200 --> 01:17:39.600
a really good example of that he's done all the things he's taken the handfuls the supplements
824
01:17:39.600 --> 01:17:44.640
but then he started to look at like meditation and prayer and psychedelics and all these other
825
01:17:44.640 --> 01:17:49.040
things like yeah yeah you getting back in the middle and the center of this whole balance thing
826
01:17:49.040 --> 01:17:52.560
well he was starting to look like he needed to honestly so I'm glad that he's
827
01:17:54.320 --> 01:17:59.360
yeah I definitely think balance is something that never was sexy and never really was click
828
01:17:59.360 --> 01:18:05.680
baby but I'm starting to see that messaging come up through with influences and I think it's just
829
01:18:06.320 --> 01:18:11.840
the the burnout potential for trying to be perfect all the time actually creates the opposite
830
01:18:11.840 --> 01:18:16.000
effect that what you're going for it just doesn't work if you're trying to be perfect all the time so
831
01:18:16.640 --> 01:18:22.800
yeah acceptance of imperfection in biohacking and health this is something I'm actually all for
832
01:18:22.800 --> 01:18:26.960
life life's meant to be lived and if you if you get a 70-sleeve school one day just don't
833
01:18:26.960 --> 01:18:33.680
throw it about it and chuck it chuck a tantrum like some people can get older yeah love it all right
834
01:18:33.680 --> 01:18:38.720
last question my friend if you could remove one piece of bad advice from the health industry entirely
835
01:18:38.800 --> 01:18:45.200
what would it be these chat GPT prompted influences who pretend to be experts that's really annoying
836
01:18:45.200 --> 01:18:51.040
and there's nothing stopping it other than I guess the counter to it is the people who aren't experts
837
01:18:51.040 --> 01:18:57.200
just don't believe everything in influencer myself included if you need to audit what I
838
01:18:57.200 --> 01:19:00.960
please audit what I say to be true before you just go ahead and change your whole life based on it
839
01:19:00.960 --> 01:19:07.280
like I do my best to deliver factual information based on over 10 years of looking into this stuff
840
01:19:07.280 --> 01:19:12.240
versus it's trendy to talk about peptides now and you got an affiliate code to sling in and
841
01:19:12.240 --> 01:19:17.120
sling in some injectables so I'll just get chat GPT or Claude to make a script for me and pretend
842
01:19:17.120 --> 01:19:24.080
I'm an expert at my gripe yeah okay it's a good one it's a really good one all right Kyle van
843
01:19:24.080 --> 01:19:32.240
release tell people where to find you I don't know I'm dead we've been killed by the power to be
844
01:19:32.720 --> 01:19:37.520
social media but I always like the evergreen line our email list is how we're communicating now
845
01:19:37.520 --> 01:19:44.080
considering we are so stifled by meta so media and meta and even Google and all the other ones
846
01:19:44.080 --> 01:19:49.920
don't really like how accessible peptide information is from both our platforms and both our
847
01:19:49.920 --> 01:19:54.640
ourselves so yeah we're level up health calm and you should probably get a pop-up that's
848
01:19:54.640 --> 01:19:58.560
from you to join it that's probably the best way to do it getting on that like that's where we
849
01:19:58.560 --> 01:20:03.040
communicate all the time now and yeah we'll have to figure out some other ways to get the message
850
01:20:03.040 --> 01:20:08.160
out there now that suppression's rampant and are pretty debilitating to the business unfortunately
851
01:20:08.160 --> 01:20:12.240
that's been a challenge over the past few months is when you can't speak and share your message
852
01:20:12.240 --> 01:20:18.000
and your product it does actually affect obviously while the business is doing so it's been a
853
01:20:18.000 --> 01:20:22.960
challenge but yeah getting on that email list is the way that you can support and be informed
854
01:20:22.960 --> 01:20:27.760
of all these new product drops and all the educational stuff that we've been working on for the past
855
01:20:27.760 --> 01:20:34.720
year and all beautiful and folks if you decide to shop while you're you're you're signing up for
856
01:20:34.720 --> 01:20:42.320
the newsletter on the website what's our latest code is it net 10 net 15 net we want you out
857
01:20:42.320 --> 01:20:49.280
from 10 and net 15 or just not one of those are work for sure so net or net 15 and you get to
858
01:20:49.280 --> 01:20:56.080
save 15% off either one thank you so much for all your time and thank you for letting me
859
01:20:56.080 --> 01:21:01.680
ring out your brain today and just pepper you with questions and I'm looking forward actually
860
01:21:01.680 --> 01:21:06.560
looking forward to our next interview which will be for the bioregulator and peptide summit that
861
01:21:06.560 --> 01:21:11.920
comes out in August you actually triggered my response to a previous question black pep is my
862
01:21:11.920 --> 01:21:20.080
crop in the industry I hate that stuff yeah I put you with questions there you go so black pepper
863
01:21:20.560 --> 01:21:27.280
that people use for biotech of ingredients yep yep creates permeability of the garden inhibits
864
01:21:27.280 --> 01:21:34.480
glucoronodation a critical liver detoxification step and on that note and on that note thank you so
865
01:21:34.480 --> 01:21:40.960
much and we'll see you again soon if folks just a quick reminder that all of the information presented
866
01:21:40.960 --> 01:21:48.560
in this podcast is for information purposes only no medical advice no diagnosing no treatments
867
01:21:48.560 --> 01:21:53.520
suggested here before you try anything that you hear about or learn about here make sure that
868
01:21:53.520 --> 01:21:57.120
you check with your medical provider
1
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Welcome to Longevity. I'm your host, Natalie Nidom. I'm a nutritionist, a human potential
2
00:00:11.800 --> 00:00:16.560
and epigenetic coach, and I created this podcast to bring you the latest ways to take control
3
00:00:16.560 --> 00:00:20.920
of your health and longevity. We cover it all from new technology and ancestral health
4
00:00:20.920 --> 00:00:25.760
practices, to personalize interventions, and a very special interest of mine, peptides
5
00:00:25.760 --> 00:00:32.040
and bio regulators. Enjoy the show. Welcome back to the show. Everybody, my name is Natalie
6
00:00:32.040 --> 00:00:38.640
Nidom, and I am your host. Now, before we get started, very quick favor. My Instagram
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00:00:38.640 --> 00:00:44.120
account has, well, let's just say it's vanished. And I'd really still love to share and be in
8
00:00:44.120 --> 00:00:49.120
touch with all of you. So if you want to stay up to date and stay in touch with me, aside
9
00:00:49.120 --> 00:00:54.840
from signing up for my newsletter at natnidom.com, you can also follow me at my new Instagram
10
00:00:54.840 --> 00:01:01.320
account, which is at longevity with nat. Okay, let's get into this episode. Kyle Vendor
11
00:01:01.320 --> 00:01:07.080
Least is back. His story may sound familiar to you, mold illness, love of food of medicine,
12
00:01:07.080 --> 00:01:12.320
a death of someone near and dear to him in his family, and a drive to engineer formulas
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that actually work. We're digging into how he builds formulas from the ground up, focusing
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on mechanisms, not just ingredients, expect blunt truths about product quality, why you
15
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should care about bioavailability, and how he balances long-term outcomes with fast
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acting wins for brain and gut health. Now, if you want to learn more about any of Kyle's
17
00:01:31.560 --> 00:01:40.600
level up formulations, head on over to leveluphealth.com and use code nat for 20% off. And level up has
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00:01:40.600 --> 00:01:49.760
no ease in it. L-D-L-U-P-H-E-A-L-T-H.com and use code nat. Next up, we'll thank a couple
19
00:01:49.760 --> 00:01:55.720
sponsors that make this podcast possible and then we're off. What if doing less actually
20
00:01:55.720 --> 00:02:01.200
helped your body do more? We're constantly adding things to our routines, more supplements,
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00:02:01.200 --> 00:02:06.960
more workouts, more products, more protocols. But if your body is stuck in stress mode,
22
00:02:06.960 --> 00:02:12.960
none of it really lands the way it should. Your wire tired and never really quite recovering.
23
00:02:12.960 --> 00:02:18.480
Now one thing I keep coming back to is my infrared sauna, not as a push harder tool, but
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00:02:18.480 --> 00:02:24.240
as a reset. A few sessions a week, sometimes short, sometimes longer depending on how I feel,
25
00:02:24.240 --> 00:02:30.320
and it helps my body shift gears. Infrared sauna therapy uses light energy, not just heat,
26
00:02:30.320 --> 00:02:35.760
to gently warm your body from the inside out. That supports mitochondrial energy, circulation,
27
00:02:35.760 --> 00:02:42.160
detoxification pathways, and most importantly, your nervous system. And I use sun lighten because
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00:02:42.160 --> 00:02:47.840
they've been leading this space for over 25 years. Their full spectrum infrared plus integrated
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00:02:47.840 --> 00:02:53.520
red light makes it a one-stop session. And they have options that actually fit real homes
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00:02:53.520 --> 00:02:59.840
and real budgets. Everything from your full cabin sauna to a solo portable version.
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00:02:59.840 --> 00:03:05.040
So if you're building a smarter longevity routine, this is a foundational piece.
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Learn more and save up to $1,600 plus get free shipping on your sauna purchase when you visit
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sunlighten.com and use code net longevity. I didn't realize how on edge my body was until it
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finally wasn't. You know that feeling where you're technically sitting still, but your nervous
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00:03:23.600 --> 00:03:28.480
system is still sprinting. Like your body didn't get the memo that the workday is over. Well,
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I felt just like that. So instead of piling on more supplements or trying to force relaxation,
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I started using Apollo Neuro as part of my daily routine. Apollo is a wearable device that I
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am now addicted to. You wear it on your wrist or your ankle or even clip to your t-shirt around
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your neck and it delivers vibrations to your body for completely different nervous system needs
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as they come up. So what's different here versus any other vibration wearable is their smart
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00:03:57.040 --> 00:04:02.640
vibes tech. It's not just a one size fits all vibration. It actually learns your patterns.
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I can manually manage it or I can leave it and it adjusts based on what my body needs.
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So it feels less like I'm doing something and more like my system is being guided.
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It's literally like a dimmer switch instead of an on-off button. Over time,
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I've noticed I'm more steady during the day, way better at shifting into rest mode at night.
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I sleep better and I even see my HRV numbers improving. So if your nervous system feels like
47
00:04:28.080 --> 00:04:33.520
it's stuck in overdrive, this is probably worth a try. There are modes for focus, sleep,
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calming anxiety, increasing performance and so much more. Just head on over to ApolloNuro.com
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00:04:39.840 --> 00:04:44.960
forward slash NAT and use code NAT and you get to save 99 dollars on your purchase.
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Kyle Vendor Least, welcome back.
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Man, that's eating it. I'm round four. Thank you for having me back.
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Is it round four? Is that it? Four or five. It's kind of a lock of it. It's been a journey over
53
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the years and it's good to break connect again. It's been a hell of a journey since then and
54
00:05:04.400 --> 00:05:11.360
your company have exploded incredibly over the last number of years and it's been a total
55
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honor to watch you expand the way that you have. It's been really amazing. To that end,
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you've gained so much knowledge, insight and experience as you've been going. In your opinion,
57
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what's the biggest mistake you feel they're people are making when they try to fix their health
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and why do most supplement stacks actually tend to make them worse?
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One of the biggest mistakes, definitely, this is it, is just jumping on Amazon or I have and
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doing a quick GPT or Google search of what can help and then they just go straight to the bottom
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end for the price. One thing I've always had to apologize for but kind of unapologetically,
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it's the reality of the brand is we are expensive for a reason. Every product, every ingredient
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we source goes through rigorous testing, quantitative, qualitative analysis, looking at the
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constituents, quantifying what percentage of the herb actually has that constituent because
65
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the studies that show that a botanical extract or a vitamin does something for a disease condition
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or for cognitive enhancement or for gut health is very specific to the active found in that botanical.
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And if you just hear the word like cordyceps mushroom or something like, oh, zinc helps and then
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you just go on and you're like, oh, here's the cheapest cordyceps. There's a good chance that
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that's just absolute bug material or the industry has cut it where you get 500 milligrams of a
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cordyceps blend and they've just given you all the useless parts of it and the actual active that
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you'd want in a milligram quantifiable amount is not even in there at all or if it is, it's in my
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program amounts versus milligrams. So that's the biggest mistake that people make and I think
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the industry is getting a little better to this as people wise up to it and as we push the education
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around quality and get deeper into the mechanism of exactly and implicitly what you want from a
75
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from a supplement and even in solo ingredient ones. It's super simple. The formulas are a bit more
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complicated but yeah, that's probably the biggest mistake I see people make and then on the flip
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side after they try things and they don't work, they just go back to, if that's their entry point
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to supplements, why wouldn't you go back to pharmaceuticals when they hit you and work hard and
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then that supplement did nothing. So it's a it's a cry when people say supplements don't work
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because they absolutely do. There's just a big percentage of supplements on the market that
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actually don't so yeah. Yeah, no, that's a that's such a powerful point. People are chasing
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symptoms but they don't really often understand what the drivers of the symptoms are and so
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you take a supplement to address the symptom that doesn't really get to the reason why the symptom
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is showing up. That's probably the next layer if you will of it didn't work for me and that's
85
00:07:58.960 --> 00:08:05.600
because it wasn't what you needed. Yeah, exactly right. Symptom chasing is in naturopathy called
86
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green alapathy where we just replace a drug with a supplement that might alleviate a symptom and
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not really go for the root cause. So if you want to be on supplements for caring to try and manage
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manage a condition at the most downstream part of it, that's fine if that's your choice but
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definitely digging deeper and trying to find the root cause. There's always like if a
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car's broken or an engine like goes on you'd go straight for the problem and try and fix that
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rather than just taping over the light or fixing like a fuse or something in it. So yeah, we can
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definitely do a lot better that way. We've had you on the show a couple times so your origin story
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runs through those previous episodes and will this the episodes in the show notes? But for anybody
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who's new to the show and who doesn't know you, what's your two minute pitch on what you do and why
95
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you do it? Yeah, so I'm a trained naturopathy nutritionist from Australia. My big why behind starting
96
00:09:01.200 --> 00:09:07.280
level up is I was a primary my the primary career from my mother who had she passed but she had
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cancer and it was an eight year battle and we tried all of the supplements, all of the peptides,
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all of the biohacking things and my goodness eight years with eight years with that diagnosis that
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she had was it far exceeded any expectations people had with her and that's sort of what sparked
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my interest in supplements is is nutritionist food is medicine. What's in the food that's the medicine
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is when you get isolated supplements where they sort of distill that out of the food and super
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concentrated in in a pill. Beyond that, I've been through health challenges. I've spoken about
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Moldoric in about three of three of the podcast we've been on the first one as much but
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that was a journey and it absolutely tanked my own health and silver lining to that is a formula
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aid at risk. When you have a health problem and you have the accessibility to ingredients and
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that I do as well as the peptides you can figure out some pretty innovative ways to get better a lot
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faster than just relying on other brands attempts at liver detox support formulas or other
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neutropics to get you through it. So there's been a huge expansion of level up health's range basically
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centered around Mold for me but now that I'm not in Mold anymore and thriving I'm kind of looking
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to just have these little upgrades to sort of everyday health products. Nice I love it.
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All right so here's something that a lot of people might not know about you is that you're not
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just pulling from one discipline. You're blending naturopathy biochemistry traditional medicine
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and that discipline that we call biohacking whatever the heck that means anymore. So where did that
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hybrid thinker mindset come from? Like you you really because a lot of people say okay this is
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the way or this is what I'm going to do and you instead are like ah there's a buffet out there.
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Yeah one of my mentors said anyone who claims to have all the answers is that's the biggest red flag.
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Like I am clinic directors, chiropractors, osteopaths they all not all of them are becoming a lot
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more holistic minded but anyone who's ever claimed that this is the thing is just trying to make money
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out of you. I had to try and figure out in supplements or what would work like I have often used
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off-label medicines and stuff like that like no lotus no trexone I've spoken about that's pharmaceutical
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methylene blue technically is pharmaceutical I love both of those things they're fantastic.
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The golmura of a naturopath would usually prevent them from ever touching a pharmaceutical or
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something synthetic and just rely on nature and the herb and then the intelligence of that.
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Yeah didn't really resonate with me as strongly as using things that absolutely you can feel
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and technically and on like blood tests and mold texts organic acid tests or a stool sample you can
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see quantifiably the change happening so much faster than any other thing so that's sort of
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wire blend modalities it's just outcome based rather than you know sticking to a dogma
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of nutritionist or naturopath or whatever the heck you want to call yourself by a hacker.
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All right well how can everyone everyone can be a health coach if they decide to be on their
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profile for that qualification. Yeah no kidding so here's what we thought would be fun for today
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is if we were to discuss some common issues people deal with and the naturopath
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formulators approach to building the formulas that actually help. Are you game?
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Oh yeah oh yeah semi-quick five and I definitely get derailed into tangent so you'll have to
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I'm counting on those tangents that's where the that's where the magic is okay so when you sit down
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to create a formula what's your starting point is it symptoms pathways outcomes where do you
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where do you begin. Usually it's around the mechanism mechanistic drivers like that is the
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high-level thing like what are the key mechanistic drivers of this condition or this problem
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let's just focus it on like stress for example if we look at why someone stressed it could be
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like cortisol is the big one you want to hear it right and then adrenals adrenals might be
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malfunctioning it's stripping it back to what are all of the foundational drivers of
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of the problem you're trying to solve so try to solve the problem not create a product that might
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just happen to help with problems um liver complex that um been selling for a few years now as a
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perfect example of that we've done a whole podcast explaining the methodology behind that but
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essentially with that formula I looked at if the liver is going to detox if you're going to support
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liver health how does the liver work not what ingredients help liver and it's phase three detox
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file flow and then phase two conjugation and then phase one as well as anti-oxidant support and
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glutathione they're like the big ones there's always going to be a mechanism or another pathway that
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makes up a percentage that you just can't hit unless you like your formulas to have 40 ingredients
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which sometimes I've gotten close but generally generally I like to keep it more than like six to
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eight in a product and yeah and then concurrently too it's the next step to it would be all right we
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know the mechanisms what are the candidate ingredients for it let's look at the studies let's look at
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the research let's you know figure out what's moving the needle the most as well as frankly speaking
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I find it as useful as reading a study it's just going on forums seeing people's experience and
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like these out resounding success stories or feedback from people really triggers triggers me to dig
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deep as to how that might have happened a really good naturopathic herb that's triggered the
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shit out of me for a few years it's called indigo naturalis and I found out about that through
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a forum you interviewed Dane from Crones Collider's lifestyle a few years ago yeah he put out like a
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survey amongst this community of all of these products which ones helped you with your flair your
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colliders flares the most and that one topped mine for number two the GI repair and like ridiculous
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as if this silly little herb is helping more than my ultimate GI but I mean the user experience is
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something that's absolutely prompted me to try and bring that out because if that's helping who
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will might argue with the hundreds of people who share the best thing for their their flares for
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their IBD so those user experience things are definitely a huge factor that goes into how I
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formulate the next thing is picking the quality materials that's one of the harder things that
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you need to have a lot of discernment if you're formulating you can't just go on Google you can't
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just go on iHerb and see how the other people are doing it because a multivitamin can have synthetic
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b9 synthetic b6 cyanocabolamin instead of methylcabolamin or adenosylcabolamin and then you just
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might as well not even use the stuff yeah or you might hurt people by giving a material that needs
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methylation or it needs you know certain genetic strengths to convert it to something usable and
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for a lot of people those things can be detrimental to their health and making sure every ingredient I
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select does no harm that is the you know Dossore the doctor mantra basically first do no harm
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that's yeah how to formulate and honestly peptides do you have the ability to do it that's
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why I've started steering a little bit away from them now despite them being the foundations of
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business still mm-hmm yeah I mean the peptide story is well we'll get to it but well actually
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here's here's leads us to an next question so how do you decide between using a peptide
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or a vitamin when they all might target the same issue because the peptides pretty sexy everybody
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wants the peptide right so how do you decide yeah well usually when I formulated it's like let's
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anchor the product around a peptide that's going to do the heavy lifting you might if 100% of the
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formula is effectiveness if the peptide contributes 60 to 70% fantastic that's great let's not overlap
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the mechanism let's not use redundancy like redundant products or redundant ingredients but
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let's have things that sort of if BPC is triggering like epithelial growth factor veg F
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nitric oxide all those other pro healing pathways let's bring in hyaluronic acid which
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BPC doesn't stimulate hyaluronic acid that's a building block let's use PEA which is actually
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going to symptom relief the pain where BPC won't do that that's how I'd like to formulate
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overlapping for the actual outcome but not overlapping the mechanism unless you know you're not
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hitting that mechanism strongly enough with one ingredient yeah so what's something that most
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consumers and even practitioners completely misunderstand about ingredient synergy what what are
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people missing here ingredient synergy well I think I see it in the pre-workout space is synergy
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can be detrimental because if you hit a pathway the best one that I can explain and that I often
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accidentally overdue is acetylcholine as a like metropics so acetylcholine is the is the
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neurotransmitter associated with focus mental clarity speed and just how quickly you can recall
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your words yeah however you can push this too high and there's ingredients like alpha gpc cdp
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colline it's the other one there's a few other colline sources they are like donors of colline
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but then if you take something like hupazine serrata or hupazine A that's acetylcholine esterase
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inhibitor so it keeps that acetylcholine in your in your your own for too long and then you
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kind of overshoot it and then you get these headaches absolutely pounding headaches and all the
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focus that you had has completely been wiped away by the headache so it's really easy to there's
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always a inverse u-shap curve for dosing things and I see people just pushing things way too hard to
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try and like be a race to the claim like who has the most of this ingredient or if you can do it
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the best and the biggest and it's almost like ikawik from the formula I do more than you mine's
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bigger and sort of thing so that's one way that it's going wrong the other thing that
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I noticed is proprietary blends that I'm not even going to get into why they're problematic but
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essentially they hide things yeah in the sense that proprietary blend just allows a business or
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a company to hide expensive ingredients in that proprietary blend and basically use none of it at
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but still be able to climb it on the level yeah yeah yeah I just talked about that in a solo
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episode and the proprietary blend unless they're you know you'd get a proprietary blend that because
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the rule I guess that they made was that you only had the manufacturer only has to give the total
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weight of the blend but doesn't have to assign weight so if you have 10 ingredients in a proprietary
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blend that accounts for 500 milligrams of supplement and two or three of those need 150 or 200
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milligrams to be therapeutic you got a problem yeah and usually in a proprietary blend you'll
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find one ingredient that you probably people probably don't know what's a cheap ingredient what is
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a cheap ingredient and what's an expensive one but usually there's always a cheap ingredient in that
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proprietary blend a perfect example is lion's man mushroom so in lion's man you can have really
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high extract ratio so like a 200 to one or something like that or something standardized to a certain
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amount of an active that you're after but the other thing you can do is just blend in the whole thing
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lion's man's probably a bad example because if you do take the whole mushroom it's fine yeah
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we look at a whole herb maybe the leaf or the root is the only part of that herb that has the
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active that you're after but they'll put the the root in there be able to claim that our
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licorice roots in this yet they'll chuck the whole licorice plant leaves and all and then it
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it dilutes down the um actual part that you're after and essentially makes a product that's not
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going to work well at all but um you know it ticks all the boxes for consumers when they're looking
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to buy it yeah yeah no that's a really good point actually another good example of that is ashwagando
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where you don't want to be using the aerial parts of the plant you don't want to be using the leaves
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because there's toxins in there but that's cheap that's a cheap source of the active ingredients
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you're looking for so the cheap ingredients will use that instead of the root how do you balance
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the trade-offs or how do you think about trade-offs for example faster immediate results which
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everything everybody's after versus long-term adaptation it's always a hard one because the long
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term stuff the long play like one of our products longevity isn't one you feel immediately that
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but it is one of the most accumulative effect one of the best for accumulative effects if you
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continue to use it it's a build up effect another one is PEA it's an anti-inflammatory pain killer
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one yeah if you use it for up to a month that's when you get the best effects you still feel some
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effect in the front end um and for things like BPC or zinc or copper it's definitely
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there are potential trade-offs to long-term use so whenever I talk about taking supplements like
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everything in the range I don't want people to be on these for the rest of their life the only
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exceptions may be creative for example like if you're on that for the rest of your life that's
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probably just a smart investment and making sure your brain in muscle works better but things
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like the neuro formula the ultimate GI anything peptide based I always tell people to take a break from
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because continued use is a trade-off um the what's like an immediate problem in taking things I
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mean you can get I'll give an example we sold some test offensive for a while for like a week that
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shouldn't have done it yeah so like for disclosure we you know you know how do I thought this
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is amazing this is going to be like the next generation weight loss thing and arrival all these
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ozempics and GLP ones and and then I got it made to a high standard and wholly smokes it just
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exposed to me that no one else in the industry does that ingredient properly because when we made
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it and we made it suspect I was sweating profusely for four or five hours because that's the trade-off
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to this thing it increases damage and this is so much as well as um parasympathetic tone that you
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get all these host of side effects and it ended up feeling like horrible pharmaceutical and we
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just pulled that completely from circulation that was a lesson learned for future products to not
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push things too hard too fast and uh make sure that you find that nice balance point again similar
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to how I said like every ingredient has its optimal dose on the inverse U shaped curve well every
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ingredient that I put into them I kind of figure out where that needs to be based on evidence and also
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you know potential for long term harm or accumulative effects for example might be detrimental like
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zinc we could put more zinc in ultimate GI or higher doses but then the zinc to copper
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ratios will be thrown out so much faster yeah there's there's like a um definitely a balancing
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act everything let's talk about the zinc in ultimate GI because the number next to zinc is not
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the actual amount of zinc you're getting and that's very confusing to people people
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I've had comments from people saying oh I can't take that there's way too much zinc in there
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do you want to explain a little bit about the type of zinc that you're using and why it looks
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like it's a lot but really it's not I'll go a bigger picture at the start every single um mineral
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is killated or bound to something magnesium copper zinc sodium all of the electrolytes are bound
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to something always potassium citrate magnesium glycinate zinc alkanacene zinc piculinate or
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zinc this glycinate there's always something you don't ever get the thing in isolation it has to
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be you in supplements at least it's bound to things in diet it might be different but
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so zinc alkanacene which we use in GI repair that specific form of zinc alkanacene is selected
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because the alkanacene that the zinc is bound to is super beneficial for gut inflammation
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and all the alkanacene also allows the zinc to essentially hang around and elicit its effects in
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the gut for a lot longer and doesn't drive systemic absorption as much as it as it promotes
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local zinc saturation in the lumen so for taking a zinc supplement to rectify zinc deficiency
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for example a zinc alkanacene is not going to be as beneficial as a piculinate or a gluconate
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or something like that because it is targeted and designed for the gut it will get in circulation
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it's not to say that's a useless form but there are better forms of doing it magnesium is a fantastic
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second example because it's still a mineral and there's many different forms of which many
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people are interested in magnesium al3n8 I'll use to explain what you said about the dosing
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the dose for magnesium al3n8 is 2,100 milligrams and of that only 151 milligrams is actually
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magnesium the rest of that complex of that pairing of magnesium and al3n8 is al3n8 so
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different forms have different percentages and this is always a consideration for formulating
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because if you want to deliver an elemental amount so when you're looking at minerals you
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want to see the elemental yield or the elemental amount or equivalency that is the actual amount
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you want so like for magnesium I always like to aim for 350 to 400 milligrams if you were to try
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and get that exact amount from al3n8 you're going to have to take 4 grams worth of magnesium al3n8
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to get that amount of magnesium in circulation there's other forms you can use like magnesium oxide
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terrible absorption but 50% magnesium and the reason it doesn't absorb and gives you the runs
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is there's just too much magnesium relative to oxide and it pulled water into the into the
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gut and then you end up having the runs you can make a form of magnesium oxide called sucrezone
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or magnesium where they take that magnesium oxide that almost 50% blend of magnesium to oxide
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and then encapsulated in a sucrezone like a sucrose like lipozone and then that gets it into
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circulation and then if that you know once the magnesium oxide is in circulation then you've got
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a huge amount of magnesium that's actually made it into circulation and not caused all the GI
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upset but anyway in short the reason why you don't have to the the thing to look for and when
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dosing is the elemental amount for that the other caveat to it is when you're looking at ingredients
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like phosphatidal colon phosphatidal serine this is something manufacturers and supplement companies
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often do is you can select the percentage yield of that active like phosphatidal serine for example
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amazing for stress and focus and cortisol regulation when selecting material you can choose a 50%
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phosphatidal serine blend and basically the other 50% of that would be phospholipids and
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unfortunately and we have to spend a lot of time now excluding material suppliers often the other
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50% of that material that you're putting into your product is rice flour or cellulose or something
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like that so a lot of supplement companies whether they know it or they're just ignorant to it
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we're trying to give you 250 milligrams of phosphatidal serine but they haven't dug into the report
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from the supplier or they haven't done the third party testing to say that all that 250 milligrams
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is only 50% so the amount that you're delivering is actually meant to say 125 and this is
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something that you know we nearly got tripped up on with that particular ingredient and phosphatidal
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colon as well when the higher you go in the yield and the active the more expensive it gets because
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you are just getting what you want and what you know what is the ingredient you should deliver so
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that's another thing to to look for and often if you take a supplement that seems
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like for like versus another one and one works and the other one doesn't that's probably because
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the one that doesn't work is part of those complexes or those blends so when you're looking at someone's
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supplement stack what's a green flag versus a red flag for you what are the flags you're looking for
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I always like to see people have a magnesium in their stack I think everybody kind of needs
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magnesium nowadays making sure that they've got good forms or a blend of magnesium like we do
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one bio optimizers do a good one shout out for them for doing something well in the industry as well
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I always like a myth related if you need it I'm sort of on the edge of maybe not universally recommending
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methylated bees to everyone because I have heard a small percentage of people have problems but
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comparative to the other cheap ingredients on there that's a lot safer so yeah yeah I mean if you're
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curious about whether you need methylated bees or not which frankly most people do is just get
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your genetics run it's a one-time test and then you know and then you know what you need
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so let's say someone handed you a list of 20 supplements that they're taking how do you start
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even begin to simplify it there's plenty of people taking fistful of sub fistfuls of supplements and
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like bragging about how many they take Brian Johnson, Dave Asprey, etc in the past when I had
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mold issues oh my goodness the amount I had to take in a day was insane but um essentially just
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reverse engineer the whole thing what are you actually trying to achieve with this what do you
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goal what do you what's your intention is is foundational do you have a disease that you're trying
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to prevent or rectify or do you have struggles like I don't think anyone should if they've got
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their foundations right need to take more than like four or five supplements a day and then you
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cycle them as needed so magnesium always I always take that before sleep it just quantify
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improve my sleep so I have the justification and the rationale for that one creatine I work out a
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lot I have need the mental focus so I always take that. Neutropics are an add-on they're not
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necessarily foundational although some of the botanicals certainly help with the
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neural infrastructure and the neurogenesis and the ability to retain the information that you
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learn so I consider them foundational for you know how I live my life um but then what would
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you need to take like do you have hormonal issues as a man or a woman do you need to take something
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to support hormonal clearance if there's too much estrogen or um ones that stimulate it like
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viatex if there's not enough progesterone for a woman for a man is your testosterone mo have you
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done the blood test to see that and if yes then you know consider a tribulus or a tonka dali or
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something like that and um yeah that's it's really a case of there's so much confusion that people
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like myself in the past just through shit at the wall and saw it stuck and then often you just
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end up creating like interaction problems and too much of one b vitamin or too much of a
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acetyl a acetylcholine donor and headaches you can definitely do what people do with drugs where
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you just take too many things and they kind of canna balance each other you can do that with
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supplements there's just so much more room for error versus pharmaceuticals where there's
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you know adverse reactions inside effects yeah for sure and I think one of the things and you kind
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of alluded to it is repetition of the same compound across different supplements and now all of
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a sudden you're taking way too much of you know like even a b12 can have neurological problems if
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you're overloaded but certainly the fat soluble vitamin is the ade k you can overdo those and um
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and timing as well when you take them is important like too much b12 before bed can keep someone
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up or nine they wouldn't know why I've had a couple of people in my membership community telling
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me that they've entered all of their supplements into their chat tpt and it has come back with some
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really interesting information about well you shouldn't be taking these two things at the same time
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or did you know you're actually taking you know whatever the total milligrams is of a certain
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ingredient that is overkill so I do think that you know AI love it or hate it it's here if we
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that that would be one good use of it and then there's also a company called subcoe if you heard
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of them yeah it's an app okay yeah yeah yeah they merge with another company recently I believe but
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yeah they're just like tracking of it as well and even like full script do it as well for practitioners
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who use it they can you know when you're presenting your script to patients it often can tell you
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what you're overlapping or giving two of things so there's there's a lot of ways to prevent this
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overlap but goodness if you're just shopping on Instagram or and you know just go to a supplement
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store and it's up to you then it's it's pretty hard to monitor all that I'm definitely guilty
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aceto colon being the one that I do regularly accidentally trying different pre workouts and trying
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different new tropics and brain boosters that yeah that one always sneaks up on me yeah well
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everybody loves it right all right let's let's talk about the brain a little bit when somebody says
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brain fog what what are the actual root buckets you think through first and I'm using the word
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buckets because brain fog can be due to many different things so what's your what's your list of
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things you're going to go through for those people usually when people say they have brain fog they
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say brain frog because their brains not working better so I always just have a little trick brain fog
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what's contributing to that usually there's a huge amount of stress from something that's such an
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obvious thing that I just can't not say it you know when I had brain fog brain frog the mold
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the microtoxins were getting into my brain if people aren't sleeping well that's an obvious one
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as well if they're not eating enough food if they're nutrient deficient honestly let's touch on
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that for a second nutrient deficiency with GLP1 use that's a big one that's becoming more prevalent
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not enough calories because you don't have appetite and then also not enough micro nutrients
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because you're simply not eating enough this is horrible when I'm seeing it and you know
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those epic faces is real and a lot of it's you lost weight too fast so you've got detox reaction
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but the other part of it is you just melt nourished so yeah all right you're gonna have brain fog
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from that too that's for sure the other ones can be if you're in pharmaceutical drugs for example
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SSRI's it's a big one that can sort of make or break people and more often break and then cause
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brain fog and another one for men particularly women are affected by it too is what your hormones
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are doing like estrogen and testosterone specifically to testosterone and dopamine have a really
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strong interconnected relationship so usually the higher you dopamine is the better your
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sorry the better your testosterone is the higher you dopamine is the more motivated you are the more
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you know driven and focused you can be the other ones that go into it would just be inflammation
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that's the biggest one like when you're stressed you're inflamed when you've got mold you're inflamed
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when you've got gut issues you're inflamed uh liver issues there's so many things that
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inflame us in the world it's like the inflammatory world we live in now unfortunately that um I
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hate that that's true I really wish we didn't have to fight these things all the time but just
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looking at inflammatory markers and making sure that you're not consuming excessive seed oils and
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pesticides and alcohol all of the all the things we call them basically that's sort of the root
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cause of that beyond fixing those things like if you fix them and you still got um brain fog
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of always recommended and I think I've recommended it in a previous podcast is doing the
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braverment test just to see where your neurotransmitters are at if I don't take things to help stimulate
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my brain and get it into a certain neurochemical position I am more serotonin dominant so
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everyone has like a fingerprint for what their neurotransmitters are doing at any point in time
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you do that braverment test it takes you 20 minutes and it's pretty darn accurate because I've
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compared it versus organic acids and the organic acids give you your neurotransmitter metabolites
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so kind of gives you that ratio of dopamine de serotonin and what your seed or colleague and
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your glutamine and gather all doing so that one's a cheap easy and I think free maybe not if you go
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the wrong website but uh I really get way to see where you're at with that and then if you want
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to push one of those pathways you can you can just do that based and but because you know what
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you baseline's at so yeah so then you can measure again exactly yeah and I think I mean to your
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point maybe one of the one of the tips we can give people is know your baselines like get some
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testing done before you start throwing a million things at your body all right so let's say you're
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seeing you know you're seeing all these issues in one person hair health skin thyroid brain function
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like how do you connect them into one system like how do you start to make sense of it
401
00:38:05.360 --> 00:38:11.200
well yeah you can't isolate one system and try and fix that like you mentioned all those symptoms
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00:38:11.200 --> 00:38:16.000
my immediate thing is oh it's probably iron deficiency if your thyroid's got a problem
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brain hell you know energy and ions a huge one and honestly I think that more and more I feel
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00:38:21.520 --> 00:38:25.840
like iron deficiency especially in women is one of the root cause drivers of thyroid issues
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thinning of hair and all that so interesting not to not to narrow in on an example like
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00:38:31.360 --> 00:38:38.320
there's always a root cause to things and that's where I really like the accessibility of blood
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tests especially the ones where you alacard are things that are actually useful for lying on
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the standard panel from a doctor's gonna completely it's useful don't get me wrong but you
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00:38:48.560 --> 00:38:53.600
probably got about 30 to 40 percent more tests that I ideally like to run to try and get into the
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functional to get those functional results and those functional markers to see sort of how you
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have to do things thyroid's a perfect example like TSH is pretty much all you're gonna get for free
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without trying to justify a T4 and forget about T3 and reverse T3 and then she got some issues so
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00:39:11.760 --> 00:39:17.200
those those last two those type T3 and reverse T3 are the most important in my opinion of that
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cascade cholesterol as well like every single blood test has its nuance and there's every within
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each one of them there's an interconnected balance of all these things and that's honestly like
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I don't think we are at the stage yet where you can upload your blood test to AI and it tell you
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what a functional coach and someone with 10 five to 10 years of experience in these things
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can but it's getting a lot better that's for sure yeah just doing the testing for sure is
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is is required I think if you really want to be specific and not just be guessing in your mind
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what are the most overlooked drivers of poor focus and cognitive fatigue right now?
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dopamine deficiency I think is a big one as well as destruction from just you know email over here
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00:40:07.200 --> 00:40:12.240
and a ping over there from Instagram and that that's all depleting dopamine and my buddy Lucas
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Owen I think you've interviewed him he talks a lot about dopamine resets and ways that you can try
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and increase your dopamine for motivation and focus I think that's a huge one that can be
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social media and technology detoxing I always you know result back to what I'm good at and that
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supplements so ingredients like triacid or urodene or urodene monophosphate have the ability to
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resensitize dopamine as well as peptides like cmax and p21 and dihexidae all can really help with
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the resensitization of the dopamine urgent neurons in the brain so you don't end up getting burnt
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out by or becoming a dopamine deficient person which you know it really sucks I've definitely been
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there with a lot of gaming I used to do when I was younger like stimulation from the game you reward
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00:40:57.520 --> 00:41:02.560
you reward you win all the time and then you know there's so many things that can take away our
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00:41:02.560 --> 00:41:07.760
dopamine and when that goes then the other ones just don't work as well okay so you it's
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almost like is it a depletion of dopamine or the receptors just get overworked and they just
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give up the ghost or a little bit about insulin resistance but for dopamine so desensitization
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00:41:18.000 --> 00:41:23.280
yeah supplementation for sure supplements can do it too like I've definitely felt amazing
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00:41:23.280 --> 00:41:27.760
drugs cocaine they all hit dopamine very well and you people who've taken those the note they
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00:41:27.760 --> 00:41:35.360
noted any more of it caffeine same same sort of theory there but I took macuna preens al dopa
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which is the direct weakness of the dopamine I took that for ages because I felt amazing actually
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00:41:39.840 --> 00:41:45.840
kind of felt euphoric on it and then I ate the loss of the sensitivity to it and I felt terrible
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00:41:45.840 --> 00:41:51.840
and unmotivated and had to basically bring myself back from macuna withdrawals or not withdrawals
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00:41:51.840 --> 00:41:59.520
but you know yeah yeah no macuna I've heard is it's and he gets thrown around as a supplement
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00:41:59.520 --> 00:42:04.880
by people and you gotta be really careful with it because you can definitely overdo it yeah
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00:42:04.880 --> 00:42:08.720
yeah in Australia they actually bend that you can't use it in supplements because of how much
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al dopa it has and potential interactions with schizophrenic drugs and honestly it's not the worst
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thing but I also I'm not for government saying what you can and can't take I think people can take
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it and abuse it and get in cop the ill effects without the government having to tell them they
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can't use it at all yeah well I mean you know I think part of it might be anyway I mean could
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is there a world where we can educate people enough so that they understand but it's pretty tough
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you know as you said before people can get pretty excited about stuff they hop on whatever medium
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they're on and start talking about it and you've got people not knowingly using something for too
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long or too often or too high a dose and and stuff can really start to go sideways and sometimes
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00:42:53.040 --> 00:42:57.920
those effects don't go away that quickly where do peptides fit into brain health versus more
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00:42:57.920 --> 00:43:03.840
traditional tools like herbs or nutrients where do you see peptides fitting in so peptides
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for brain health like peptide for gut health they're one of these tools that can achieve
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a lot more than I believe naturopathic and nutraceutical nutraceuticals can if we look at
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00:43:14.320 --> 00:43:20.320
dihexia always compare dihexia as like the peptide equivalent of lion's main mushroom except
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it's hundreds of times more powerful for the same reason why you would take lion's main P21
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00:43:27.040 --> 00:43:33.280
dihexia amazing seeing max is kind of like the peptide version of taking out alpha gpc you know
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00:43:33.280 --> 00:43:38.480
there's like for like comparisons between them that's very interesting yeah yeah way way way
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better than alpha gpc as well and as well as some downstream not downstream but some really
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00:43:44.480 --> 00:43:50.880
beneficial side effects for side effects I call them that side benefits yeah exactly yeah for
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00:43:50.880 --> 00:43:55.040
sea max and sea length and all these ones it basically just help the infrastructure of the brain
463
00:43:55.040 --> 00:44:00.320
all the blood flow to it the synapses and all you know everything you'd want for brain health
464
00:44:00.320 --> 00:44:06.480
these peptides can do and really combat potentially combat neurodegenerative diseases versus
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00:44:06.560 --> 00:44:12.240
taking lions main I feel like it's might give you one or two steps forward but if you you're in
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00:44:12.240 --> 00:44:16.400
an environment and you do have a disease it might still be two step back so you kind of like
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00:44:17.120 --> 00:44:22.400
offsetting it but not completely making inroads whereas with peptides they're strong enough as we
468
00:44:22.400 --> 00:44:27.600
know how strong peptides are they're strong enough to synergize with the nutraceuticals or the
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00:44:27.600 --> 00:44:33.600
naturopathics and actually make progress towards that towards whatever it is you're trying to treat
470
00:44:34.240 --> 00:44:39.760
yeah and you actually do stacks cmax and clink in your in some of your formulas right
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00:44:39.760 --> 00:44:46.320
not clink but cmax yeah oh cmax yeah cmax with p21 and dihexer in neuro origin and I wouldn't
472
00:44:46.320 --> 00:44:51.600
mind bringing out some clink as well eventually but the peptides have been really hard to source
473
00:44:51.600 --> 00:44:57.920
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00:46:06.720 --> 00:46:13.040
you get to use code NAC 10 for 10% off let's say somebody wants better focus tomorrow
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00:46:13.680 --> 00:46:19.200
versus someone who wants better brain health 10 years from now how would you design different
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00:46:19.200 --> 00:46:24.560
strategies for those two people. Immediate focus you can throw all of the nitripics out at the
488
00:46:24.560 --> 00:46:30.000
alpha GPC is going to help a little bit long term but short term as long as that
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00:46:30.000 --> 00:46:35.920
colline is in your synapse it'll be working it's kind of like a caffeine thing you're not gonna
490
00:46:35.920 --> 00:46:40.320
taking caffeine by itself you know there's antioxidant anti-inflammatory benefits of the
491
00:46:41.120 --> 00:46:46.400
coffee bean that can be a benefit long term but the short term effect the half life of the
492
00:46:46.400 --> 00:46:52.400
ingredient is sort of what gives you that immediate benefit tyrosine is a precursor to dopamine
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00:46:52.400 --> 00:46:57.920
and neurotransmitters so you can take those ones versus ones that are more of an investment
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00:46:57.920 --> 00:47:03.120
based thing so lion's mane is more of an investment based thing because of the neurogenesis and
495
00:47:03.120 --> 00:47:07.040
there's there's certain pathways in the brain that are all to do with the architecture and the
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health of it and it doesn't just apply to the brain it applies to the whole body really like what's
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going to help the mitochondrial support ones if you're supporting mitochondria with mitochondrial
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00:47:16.640 --> 00:47:22.960
supportive ingredients and MN or uralithin or whatever it is that is basically making the machinery
499
00:47:22.960 --> 00:47:27.840
better to produce more energy the more energy the cell has the better it can structure and function
500
00:47:27.840 --> 00:47:33.920
and then you know also contribute to the organ environment to like one cells functioning well sort
501
00:47:34.560 --> 00:47:38.880
ripple effect helps the other ones and then it's a feed forward effect that way
502
00:47:40.640 --> 00:47:45.760
for brain health the big ones that I really like are lion's mane seven eight dhf which is a
503
00:47:45.760 --> 00:47:53.600
flavonoid that's more powerful than even lion's mane wow I like ginko for blood flow go to collos
504
00:47:53.600 --> 00:47:57.680
also blood flow so improving circulations another good one that's going to help every organ in
505
00:47:57.680 --> 00:48:02.800
the body if you've got good blood flow via nitric oxide and circulatory support as well as the
506
00:48:03.920 --> 00:48:08.960
it's like you pick when I'll cook you 10 that's also fantastic for blood and cart
507
00:48:08.960 --> 00:48:14.320
cardio vascular also you asked a question earlier like how do they interplay like everything
508
00:48:14.320 --> 00:48:19.040
interplays blood flow is like very become very popular and there's lots of companies bringing out
509
00:48:19.600 --> 00:48:24.640
B-dex tracks and ones that help with nitric oxide and I'm really in support of those ones because
510
00:48:24.640 --> 00:48:29.120
blood flow is just going to ripple effect help every organ in the body we need the blood and
511
00:48:29.120 --> 00:48:33.360
the nutrients for them to work probably and that's you know we can go for brain health will
512
00:48:33.360 --> 00:48:38.880
definitely contribute to long-term yeah but the short-term ones are just quick like caffeine just
513
00:48:38.880 --> 00:48:44.000
think of them like caffeine quick it quick it just and that's great quick it's worth don't they
514
00:48:44.000 --> 00:48:49.680
they do but you I think to me you want to do both it's great to do the immediate stuff of course
515
00:48:49.680 --> 00:48:54.800
everybody wants their brain firing but you want to do it in a way that's a think of it as an
516
00:48:54.800 --> 00:49:00.560
investment right like what you're doing for the short-term and I and maybe this is a good question
517
00:49:00.560 --> 00:49:05.200
like are there things that people are doing for short-term gains that might be compromising their
518
00:49:05.200 --> 00:49:13.280
long-term brain health it's a good question I'm just trying to think about what people are doing
519
00:49:14.160 --> 00:49:20.240
yes definitely I think that we if we look to the stimulant space in pre workouts people
520
00:49:20.240 --> 00:49:23.920
depend on caffeine and then they need more and more and more and then they actually
521
00:49:23.920 --> 00:49:28.480
doesn't necessarily hurt their brain health directly but then they'll end up being burnt out
522
00:49:28.480 --> 00:49:32.480
their adrenals aren't functioning right and then when your adrenals go and then your energy
523
00:49:32.480 --> 00:49:38.160
goes to shit then all of the positive habits like exercise and doing all of the things that
524
00:49:38.160 --> 00:49:42.160
contribute to overall health that can really fall off so you don't want to do things that can
525
00:49:42.160 --> 00:49:47.760
potentiate or bring on burnout and nothing that's going to compromise your thyroid to and that
526
00:49:47.760 --> 00:49:53.520
can be prolonged key to genetic diets for example that can be fasting for a week you know every
527
00:49:53.520 --> 00:49:57.280
every month those sort of things that put your body into hibernation mode and shut down your
528
00:49:57.280 --> 00:50:02.480
thyroid like interventionally short-term yes that's fine but not long-term I definitely burnt
529
00:50:02.480 --> 00:50:07.840
myself out with doing keto and carnivore too long I you know make mistakes and then I learned
530
00:50:07.840 --> 00:50:13.280
from them and people I think some can thrive on it but I honestly don't think that would be
531
00:50:13.280 --> 00:50:19.840
beneficial to do for a long period of time and could hurt brain health indirectly yeah well
532
00:50:19.840 --> 00:50:24.560
I think I think that it's it's again it's one of those things it depends what your goals are
533
00:50:24.560 --> 00:50:29.440
right if cancer is a real issue for you maybe that a little more fasting is right but if you're
534
00:50:29.440 --> 00:50:34.960
trying to build muscle for longevity too much fasting is not going to serve those goals
535
00:50:34.960 --> 00:50:39.120
on that query it's like short-term versus long-term well if you've got cancer then the short-term
536
00:50:39.120 --> 00:50:44.720
is the immediate focus and the long-term is like our high will let's deal with it later you do
537
00:50:44.720 --> 00:50:48.480
that right yeah yeah if your thyroid does to go down but you bait and you can say you can fix
538
00:50:48.480 --> 00:50:54.240
the thyroid but you don't want to have to fix the other one yeah yeah a hundred a hundred percent
539
00:50:54.240 --> 00:50:58.880
all right so let's go and move into organs and systems when you zoom out which organ systems do you
540
00:50:58.880 --> 00:51:06.320
think are the higher give us the highest leverage for longevity okay so muscles always the one
541
00:51:06.320 --> 00:51:11.360
that people have to talk about yeah yeah sing into the choir right now like muscle health there's
542
00:51:11.360 --> 00:51:21.840
peptides that are actually coming into the fray now for muscle support is that Luca talking about
543
00:51:21.840 --> 00:51:30.960
TB4 yeah we're not even editing this out you guys how old is Luca Luca is three and a half and
544
00:51:30.960 --> 00:51:35.920
he's a little you know I probably shouldn't admit this he's a peptide baby I'm saying around
545
00:51:35.920 --> 00:51:42.320
like taken some products during her pregnancy and yeah he's three and a half is the apple of my
546
00:51:42.320 --> 00:51:47.440
and he's he's awesome and he also likes his own card thing evidently and he's super cute so you
547
00:51:47.440 --> 00:51:52.880
started with muscle which you know it's the darling of the organ systems for longevity these days
548
00:51:52.880 --> 00:51:59.440
because of all of the benefits and frankly even for the brain what else so how we can help support
549
00:51:59.440 --> 00:52:07.520
the muscle or finish that loop is hmb um lucine you know all these antibiotics um amino acids having
550
00:52:07.520 --> 00:52:13.120
a full spectrum of amino acids is a great way of doing it uh peptis strong peptide dilucines
551
00:52:13.120 --> 00:52:17.760
another one that these are too fully compliant you know you can buy them anywhere peptides
552
00:52:17.760 --> 00:52:22.800
that are not like the other peptides but they're still beneficial that's for sure ones that uh in
553
00:52:22.800 --> 00:52:28.720
like dilucine is just too lucine amino acids put together to make a peptide so it fits under
554
00:52:28.880 --> 00:52:33.520
that category but it's not like the ones that have these um what am I trying to say these
555
00:52:33.520 --> 00:52:39.440
transcription regulatory issues yeah exactly they don't have the regulatory issues but then they
556
00:52:39.440 --> 00:52:45.040
also aren't going to work on multiple multiple different things like a BPC will there's really
557
00:52:45.040 --> 00:52:49.280
specifically for one thing the other thing for longevity that I mentioned earlier was the blood flow
558
00:52:49.280 --> 00:52:54.080
making sure you've got the blood flow and then the bigger one that feeds in concurrently with
559
00:52:54.080 --> 00:52:59.120
blood flow is blood sugar balance so it can be something that can help restore that
560
00:52:59.120 --> 00:53:03.680
anything you do like the muscle and exercise is going to regulate your blood sugars but um
561
00:53:03.680 --> 00:53:08.400
prolonged blood sugar issues like diabetes, circulatory issues all come from from uh
562
00:53:09.520 --> 00:53:16.560
dysregulated insulin and um fasting blood sugars or fasting and fed blood sugars
563
00:53:16.560 --> 00:53:21.040
trying to normalize that blood sugar curve throughout the day and have it not go on massive
564
00:53:21.200 --> 00:53:27.120
excursions up and downs is definitely a beneficial thing for longevity. Yeah I would agree with that for
565
00:53:27.120 --> 00:53:31.600
sure and do you have certain compounds that you think are particularly helpful in helping people
566
00:53:31.600 --> 00:53:37.040
in that world? Yeah um I used to use metformin and I've completely moved away from talking about that
567
00:53:37.040 --> 00:53:41.680
and using it because there are naturopathic ingredients that are better that I think dihydro
568
00:53:41.680 --> 00:53:48.320
burberine would be a candidate as a replacement or an alternative to that one regular burberine
569
00:53:48.320 --> 00:53:54.400
is good too but here's a pharmacokinetic fun fact about regular burberine you need about 500
570
00:53:54.400 --> 00:53:59.360
milligrams to a thousand milligrams of it and of that only about one percent of it of it absorbs
571
00:53:59.360 --> 00:54:04.560
so it's terrible absorption and can cause a lot of GI upset because 99% of it is hanging around
572
00:54:04.560 --> 00:54:11.040
in your gut and then modulating um microbiome and you can have a lot of um die off reaction
573
00:54:11.040 --> 00:54:17.200
potentially from burberine and burberines often use for candida and um intestinal overgrowth because
574
00:54:17.280 --> 00:54:24.960
of that pharmacokinetic fact that it does have anti um microbial effects and if you're taking it
575
00:54:24.960 --> 00:54:29.600
for the purposes of blood sugar regulation you need to be aware that that 1% is going to help so
576
00:54:29.600 --> 00:54:34.480
taking burberine will help too but I'm modified to metabolite a burberine dihydro burberine
577
00:54:35.200 --> 00:54:40.400
absorbs about I think like 50 times better than regular burberine so you don't need to do mount
578
00:54:40.960 --> 00:54:44.800
and it's going to get into circulation so you don't have to worry about the gut issues
579
00:54:44.800 --> 00:54:50.400
and then it's going to have that you know blood sugar regulating um it drops it yeah it just normalizes
580
00:54:50.400 --> 00:54:56.080
blood sugar and works similar to metformin uh other ones grains of paradise is awesome for that one
581
00:54:56.080 --> 00:55:02.880
too um what's the our friend Sean Wells is alive and well in this podcast both of those are uh
582
00:55:02.880 --> 00:55:09.040
dilucine dihydro burberine and grains of paradise those are all Sean Wells molecules
583
00:55:09.040 --> 00:55:11.040
all right I'll get away from Sean chromium
584
00:55:11.120 --> 00:55:16.080
yeah well I actually I think it's great I mean he's he's a great resource in the industry right
585
00:55:16.720 --> 00:55:22.080
chromium b1 they're also beneficial as well and yeah there's there's plenty of other things like
586
00:55:22.080 --> 00:55:28.480
OVA is another one that's a fat burner and helps blood sugar and yeah there's there's an absolute
587
00:55:28.480 --> 00:55:33.200
treasure trove of ingredients that you can use for blood sugar control but when I focus in on the
588
00:55:33.200 --> 00:55:37.840
most hard hitters it's the dihydro burberine for sure the relationship between liver function
589
00:55:37.920 --> 00:55:43.840
hormones and energy from a formulation perspective I'm making it work for today my friend
590
00:55:46.320 --> 00:55:51.920
the relationship between liver hormones and energy right okay that's a big one I it actually
591
00:55:51.920 --> 00:55:56.240
tell people to go back and listen to our liver episode I think we yeah that was a good one
592
00:55:56.240 --> 00:56:01.280
yeah you can't bother it I'll just do it really quickly yeah um liver metabolizes all your hormones
593
00:56:01.280 --> 00:56:06.320
basically it is the clearance house for them estrogen testosterone progesterone cortisol all
594
00:56:06.320 --> 00:56:13.120
them for processed and removed by the liver you need to support liver health to support healthy
595
00:56:13.120 --> 00:56:19.600
hormone clearance and hormones like thyroid for example is converted to T3 primarily by the liver
596
00:56:19.600 --> 00:56:24.400
so if you've got liver congestion if you're a male who's been in the gyms taking exandrolone or
597
00:56:24.400 --> 00:56:29.520
some testosterone thing that's you know all issues with the liver or if you're like me living in
598
00:56:29.520 --> 00:56:33.760
mold and had chronically elevated liver enzymes because of that information then you're not
599
00:56:33.920 --> 00:56:36.880
going to be processing your hormones properly because the liver's overburdened
600
00:56:38.080 --> 00:56:43.360
bile often feeds in hand in hand with the liver and if you're not bile is one of the primary ways
601
00:56:43.360 --> 00:56:49.600
that you clear your hormones so if you want good hormonal health you pretty much as a as a foundation
602
00:56:49.600 --> 00:56:56.400
need good liver health as well um it's not I don't think it's the most common problem that people
603
00:56:56.400 --> 00:57:01.920
will have from a genetic perspective um but it definitely you know how we clear hormones without
604
00:57:02.080 --> 00:57:06.560
like what our methylation was our comps doing and what you know all that conjugate how they were
605
00:57:06.560 --> 00:57:11.440
but how does our body conjugate our hormones and remove them properly that's a huge thing that can
606
00:57:12.000 --> 00:57:16.560
upstream affect what our hormones are actually doing in circulation because of the feedback
607
00:57:16.560 --> 00:57:22.080
loops of the hormones yeah and also gut health feeds into that too because when we clear our hormones
608
00:57:22.080 --> 00:57:28.320
they can end up recirculating if we've got bacterial overgrowth or um you know we deep
609
00:57:28.320 --> 00:57:35.440
deep glucoronidase enzymes in our gut from candida can recirculate a lot of the estridans as well
610
00:57:36.480 --> 00:57:40.800
and then how does that feed into energy or thyroid implicitly linked to energy and how much
611
00:57:40.800 --> 00:57:46.240
how well you feel um even cortisol how that's clear it's affected by the liver too so
612
00:57:46.240 --> 00:57:52.000
you might have a broken diurnal cortisol rhythm because of your body's inability to clear it
613
00:57:52.000 --> 00:57:57.440
or you know overburdening of the enzymes that sort of break it down or make it go back and forward
614
00:57:57.440 --> 00:58:02.960
between um the cortisol and cortisol too if you take care of your liver and as you said like go
615
00:58:02.960 --> 00:58:09.520
back to that liver episode guys because it's at the center of of hormones and energy quite frankly
616
00:58:09.520 --> 00:58:16.800
if your liver is congested nothing's gonna work like it just it's you know we think of so many
617
00:58:16.800 --> 00:58:22.000
other organs as being the most important organ but that organ it's a it's a heavy lifter
618
00:58:22.960 --> 00:58:27.920
yeah absolutely and often when it's not lifting and the skin and the kidneys are the ones that
619
00:58:27.920 --> 00:58:32.080
pick up the slack so if you have those issues then look to live a first and then if your liver's
620
00:58:32.080 --> 00:58:35.920
not resolving look to gut because the gut and the liver access is another one that's huge
621
00:58:36.480 --> 00:58:41.840
yeah we need to consider yeah and it's funny you say that because you know for even for teenagers
622
00:58:41.840 --> 00:58:47.440
who are dealing with skin issues with acne very few people will say take care of your liver
623
00:58:47.440 --> 00:58:51.520
and delivers busy at that point there's a lot of hormones they're not eating as well as they
624
00:58:51.520 --> 00:58:56.640
should be sometimes taking care of liver and gut health can be the best rather than slapping
625
00:58:56.640 --> 00:59:01.840
something on top your skin can actually be much more effective I'm definitely a fan of skincare
626
00:59:01.840 --> 00:59:06.000
now that we've been trying to bring out skincare for three years but at the same time I'm always
627
00:59:06.000 --> 00:59:11.840
root cause like if your skin's bad you know the the external um approach is not gonna you know
628
00:59:11.840 --> 00:59:15.760
the little long term results and you just be fighting at the whole time versus root cause
629
00:59:15.760 --> 00:59:21.840
yeah start from the inside all right so hard health how do you approach it differently from a
630
00:59:21.840 --> 00:59:28.560
formulation perspective compared to conventional advice heart health all right so blood flow is how
631
00:59:28.560 --> 00:59:33.760
I look at that one um naturopathically I don't I really really really really really really like
632
00:59:33.760 --> 00:59:39.280
TB4 fragments and TB500 for heart health I think that's probably it's most that's probably
633
00:59:39.280 --> 00:59:43.600
the most powerful of all of the peptides for heart health you can correct me if you have a different
634
00:59:43.600 --> 00:59:48.880
opinion but in my opinion those fragments um one of the two I've forgotten which one um is really
635
00:59:48.880 --> 00:59:56.560
good as an anti-fibroidy yeah the heart bioregulators I remember the name of all and there's too many
636
00:59:56.560 --> 01:00:01.040
and they all sound the same this is a heart bioregulator hearty agent hearty agent not
637
01:00:01.040 --> 01:00:06.160
at the heart killer killer heart which is the same as cardiogen only it's the natural versus the
638
01:00:06.160 --> 01:00:12.560
synthetic I didn't need to remember I got you here to help me all good so bioregulators yes
639
01:00:13.280 --> 01:00:20.080
yeah um I I believe naturopathically some of the most powerful things for cardiovascular health
640
01:00:20.080 --> 01:00:25.440
you're gonna look at things like nato kinase and cerepeptase yeah fantastic anti-fibrogenic
641
01:00:26.400 --> 01:00:31.920
enzymes they break down fibrin and they also have the ability to sort of dissolve away any sort of
642
01:00:31.920 --> 01:00:37.760
plaques and any um build-ups of things you don't want in circulation and I'd say heart attacks
643
01:00:37.760 --> 01:00:42.720
is essentially just clots and you know problems that are a circulatory thing that sort of manifest
644
01:00:42.720 --> 01:00:47.680
and find their way into the heart and same with stroke so if we're taking a lot of there's been a
645
01:00:47.680 --> 01:00:52.640
lot of study around low-dose aspirin and I'm not recommending that I'm recommending instead
646
01:00:52.640 --> 01:00:58.000
low-dose nato kinase um for the same benefit of aspirin thins of blood and that's why it's
647
01:00:58.000 --> 01:01:04.160
beneficial right so if we can take something like a nato kinase for example um it can really help
648
01:01:04.160 --> 01:01:09.680
with you know that blood flow purely from the thinning effect it has white willow bark is the
649
01:01:09.680 --> 01:01:14.800
natural alternative to aspirin and you're going to get this with salison from that as well and
650
01:01:14.800 --> 01:01:21.280
that can be that can be beneficial for thinning the blood astrics it's got that inverse you curve
651
01:01:21.280 --> 01:01:24.960
as well too much of that tooth in a blood you get a paper cut and then you bleed for 20 minutes
652
01:01:24.960 --> 01:01:30.800
you probably can take it easy on those ones um but yeah for heart health I also look towards
653
01:01:30.800 --> 01:01:36.160
ubiquinol koki-ten yeah that's really implicitly linked in mitochondria after when your heart
654
01:01:36.160 --> 01:01:40.720
got a very high density of mitochondria it's probably one of the most I think it is the most
655
01:01:40.720 --> 01:01:45.680
dense organ for mitochondria so anything that's going to support mitochondria will help your heart
656
01:01:45.680 --> 01:01:49.920
and I think yoga months another one that's really good like a cut of your protective and circulatory
657
01:01:49.920 --> 01:01:58.480
supporting one yeah yeah beautiful all right so in your opinion what's one system in the body
658
01:01:58.480 --> 01:02:03.760
that you think is quietly driving a lot of dysfunction but doesn't get nearly enough attention
659
01:02:05.040 --> 01:02:14.000
what are we overlooking it's a good one um look for my personal experience lung health and that one
660
01:02:14.000 --> 01:02:19.680
is a hard one effect now oxygen and I was talking about blood flow but upstream the blood flow
661
01:02:19.680 --> 01:02:25.120
where does it come from your lungs and your your ability to breathe properly I think a lot of the
662
01:02:25.120 --> 01:02:30.880
winds are for improving cardiovascular health and lung health come from doing exercise doing breath
663
01:02:30.880 --> 01:02:36.240
training uh it's the pentagre breathing I've forgotten the guy's name but he has the oxygen
664
01:02:36.240 --> 01:02:42.800
advantage book all that sort of stuff as well uh James nester is that James nester or the other guy
665
01:02:43.520 --> 01:02:50.480
or patric patric yeah patric yeah training your breath and making sure you're not shallow breathing
666
01:02:50.480 --> 01:02:58.080
nasal strips um mouth tape uh and then honestly my biggest lung issue came from the molds I had
667
01:02:58.080 --> 01:03:02.880
like lung issues because of the mold and a lot of people do as well um but yeah lung health is a
668
01:03:02.880 --> 01:03:07.600
huge one that I think is upstream to all of this oxygenation we're looking for yeah and
669
01:03:07.600 --> 01:03:11.760
we still improve it there's not too many supplements there's a few that I'm been looking at I'm
670
01:03:11.760 --> 01:03:18.480
going to be bringing out quarter seps is fantastic for anything that improves like athletic VO2 max
671
01:03:18.480 --> 01:03:22.960
yeah high hypothesized what it's going to help your lungs if it's helping with that
672
01:03:22.960 --> 01:03:27.920
be it from circulation or from improving lung health so that's um a product I'm bringing out soon
673
01:03:27.920 --> 01:03:33.200
called VO2 max with quarter seps a really good quarter sepses extract as well as a patented
674
01:03:33.200 --> 01:03:40.480
ingredient called oxygen which um helps with oxygen delivery so yeah there's a non blood flow
675
01:03:40.480 --> 01:03:45.920
enhancing ways of improving you know your circulatory and lung health those are some big ones that
676
01:03:45.920 --> 01:03:51.200
I really um think upstream quite a quite a few systems well it's interesting you're bringing up
677
01:03:51.200 --> 01:03:56.240
quarter seps for lung because the first time I learned about quarter seps was my husband was going
678
01:03:56.240 --> 01:04:01.760
to climb Kilimanjaro and I was looking for is there anything in this supplement world that can
679
01:04:01.760 --> 01:04:08.640
help with altitude high altitude training or function and it turns out quarter seps is one of the
680
01:04:08.720 --> 01:04:13.120
is one of those things that can actually help so there you go and I love that you brought
681
01:04:13.120 --> 01:04:18.240
up lungs because nobody talks about lungs when do you reach for peptides over herbs and when do
682
01:04:18.240 --> 01:04:27.040
you avoid them completely oh good one um for testosterone I don't see any peptides that do is
683
01:04:27.040 --> 01:04:32.400
what do a good a job of increasing that as herbs yeah I think we'll outperform them um everyone
684
01:04:32.400 --> 01:04:36.240
talks about are you going to take tessamoraline or kiss peptine and this will help with that will
685
01:04:36.240 --> 01:04:42.320
help and I just don't ever I've never seen a compelling blood panel to say that peptides help with
686
01:04:42.320 --> 01:04:49.200
hormones yeah well directly anyway um women's hormones men's hormones I think it's kind of a
687
01:04:49.200 --> 01:04:54.640
relevant I don't see peptides working there I always will look for peptides for gut health because
688
01:04:54.640 --> 01:05:00.800
I have used them for years and I know how well they work and how fast yeah um it's the speed really
689
01:05:01.600 --> 01:05:07.120
yeah yeah anything instant far instant fast results so for a brain formula I want it to work now
690
01:05:07.120 --> 01:05:12.720
today when I take it so I'll reach for them uh interchangeably with the new new tropic
691
01:05:12.720 --> 01:05:16.640
naturopathic stuff so it's kind of like like for like you can take one you take the other you can
692
01:05:16.640 --> 01:05:20.480
take them together there's no sort of nuance but for gut health like if I was to just take one
693
01:05:20.480 --> 01:05:26.480
ingredient for it it'd be BPC so there's that case versus glutamine it's not going to do much um for
694
01:05:26.480 --> 01:05:31.280
you to be honest it'll help but over a couple months sort of thing it takes time people get
695
01:05:31.280 --> 01:05:36.880
uh they people get frustrated before they really get the results yeah and then back to herbs too
696
01:05:36.880 --> 01:05:41.520
I always go for herbs it's still a hormone for cortisol burn out herbs in vitamins are going to
697
01:05:41.520 --> 01:05:48.800
work a lot better for burnout for stress management um so like a ashwagandha or a holy basil or
698
01:05:48.800 --> 01:05:55.280
a rodeo much better for modulating your stress and giving you sort of energy yeah yeah those are
699
01:05:55.360 --> 01:05:59.200
sort of some use cases for it we could probably go through every system and say would you take a
700
01:05:59.200 --> 01:06:05.360
peptide for brain or a rodeo it'll be lungs and I'll be like yes to know maybe yeah is there do you
701
01:06:05.360 --> 01:06:11.120
ever avoid them completely peptides are there any situations where you're just like yeah no I'm
702
01:06:11.120 --> 01:06:16.160
avoiding GLP ones because I'm stubborn and I would like to find naturopathic ways in neutral
703
01:06:16.160 --> 01:06:20.240
natural way to try and rival them and I'm playing around with multiple different
704
01:06:20.800 --> 01:06:24.400
delivery mechanisms of different metabolites and this and that and
705
01:06:25.120 --> 01:06:30.080
all right I'm not getting close but it's maybe if we can get a third as effective and I'll be happy
706
01:06:30.080 --> 01:06:35.360
with that but yeah I'm not doing GLP ones for many reasons even though they they are an amazing
707
01:06:35.360 --> 01:06:40.000
shortcut and certainly work and everyone knows it because you know just look at like
708
01:06:40.000 --> 01:06:43.680
Debbie Moore for example how strong they can be when they're overused and you know
709
01:06:43.680 --> 01:06:48.000
these are stories from people who've done a mile and you know Tina Moore had had to help
710
01:06:48.000 --> 01:06:52.160
these educating people properly and how to dose them too so I just haven't personally reached
711
01:06:52.160 --> 01:06:57.760
for them because I'm not at the stage where I need to try all these other things first I don't
712
01:06:57.760 --> 01:07:03.280
need the confounder of oh my you know my natural GLP one worked really well I took for a
713
01:07:03.280 --> 01:07:11.600
separate time too but yeah yeah no I mean listen if you don't need them why why even go there I mean
714
01:07:11.600 --> 01:07:16.960
you know there is a storyline that they may be a very good tool for longevity down the road but
715
01:07:17.040 --> 01:07:23.600
I don't believe that unless you have like dysregulated metabolic markers or you have that need so
716
01:07:25.040 --> 01:07:30.800
you know a healthy balance system will take it over something like that any day it's just that so
717
01:07:30.800 --> 01:07:36.640
few people have that healthy balance system right now um so which leads to our next question you
718
01:07:36.640 --> 01:07:41.280
know do you think we're over relying on peptides as a shortcut or do you think they're genuinely
719
01:07:41.280 --> 01:07:48.560
a next evolution in health optimization uh over relying on them probably I will we become more
720
01:07:48.560 --> 01:07:54.720
relying on them definitely especially now they've recategorized p-cost to p-moss that now opens up
721
01:07:55.440 --> 01:08:01.360
a PCOS yeah yeah PCOS is now I've forgotten the exact way they've done it but they're basically
722
01:08:01.360 --> 01:08:06.560
described as a metabolic problem rather than a ovarian problem and interestingly a friend of mine
723
01:08:06.800 --> 01:08:11.760
shared this it's because now that now that they've made it a metabolic thing they will be able to
724
01:08:11.760 --> 01:08:16.960
probably prescribe the GLP runs for treatment of that which opens up a whole new market so we
725
01:08:16.960 --> 01:08:23.200
will be using them a lot more but I am not in I'm not against the use of them um because they are
726
01:08:23.200 --> 01:08:28.320
going to shortcut results and then if you come off of them heck I'll take that 50% reduction in
727
01:08:28.320 --> 01:08:33.840
the time it takes and the effort it takes to you know rectify a problem um and they provided you
728
01:08:33.840 --> 01:08:38.080
you can't get off them this is this is the new ones to it is you need to be able to do it properly
729
01:08:38.080 --> 01:08:41.680
not help yourself when you're on them and then be able to get off them and live your life without
730
01:08:41.680 --> 01:08:45.920
them that's that's the overall alliance problem that I see and it will it will be a problem
731
01:08:46.560 --> 01:08:53.520
yeah for sure so what's your hierarchy if someone had to choose between lifestyle supplements
732
01:08:53.520 --> 01:08:59.760
and biohacks how do you prioritize between those three lifestyle supplements and biohacks like
733
01:08:59.760 --> 01:09:04.080
a lifestyle biohacks and then supplements in that like descending order the supplements supplement
734
01:09:04.080 --> 01:09:12.000
the other things the other things feed into foundations the foundations like lifestyle if you're
735
01:09:12.000 --> 01:09:17.040
not saving properly relationships all of the things we we we talk about it ad nauseam that's
736
01:09:17.040 --> 01:09:24.560
definitely the the order to it um my my hierarchy of healing is there's foundations there's digestion
737
01:09:24.640 --> 01:09:29.840
and then there's detoxification it's like top three immune system number four hormones and then
738
01:09:29.840 --> 01:09:35.200
all of the biohacking optimizing your lipids dihexas all those other things are at the bottom of it
739
01:09:35.200 --> 01:09:40.160
because you don't need them to function really well but when you're already functioning really well
740
01:09:40.160 --> 01:09:44.960
and you just like come on and then just want to keep push it and see how good it can get that's
741
01:09:44.960 --> 01:09:51.440
when they come in yeah yeah I love that all right what's one simple intervention that consistently
742
01:09:51.440 --> 01:09:56.640
outperforms more complex stacks botanical indigo naturalis that was annoying to hear and all
743
01:09:57.200 --> 01:10:04.000
what's it called botanical what botanical GI IBD supportive one the indigo naturalis
744
01:10:04.480 --> 01:10:10.080
indigo naturalis yeah yeah that one's really good um it does have long term use problems so
745
01:10:10.080 --> 01:10:15.040
that's like a quick interventional thing that does outperform a lot of peptides which is pretty
746
01:10:15.440 --> 01:10:23.920
um ingredients themselves I've really am very strong on this new ingredient that's already in
747
01:10:23.920 --> 01:10:27.680
existence but it's not been done properly and we're working on it so I'll sneak peak what we're
748
01:10:27.680 --> 01:10:33.520
working on it's called a moden yeah yeah a moden clears cortisol to cortisol and really strongly
749
01:10:33.520 --> 01:10:43.920
it up regulates the enzyme 11 beta hydroxy something cortisol anyway yeah so it lowers cortisol
750
01:10:44.000 --> 01:10:49.120
it lowers cortisol so powerfully but the biggest limitation to it is the bioavailability being
751
01:10:49.120 --> 01:10:54.560
like 0.1% and then being cleared out by your kidney super fast so if anyone ever tries a moden
752
01:10:54.560 --> 01:10:59.600
they will notice their p looks bright orange like a blood orange because that's the moden itself
753
01:10:59.600 --> 01:11:05.120
that's the flow they um the constituents of the moden being cleared by the kidneys but it
754
01:11:05.120 --> 01:11:10.080
definitely definitely is um a moden and camp for all of the two really promising ones that I'm
755
01:11:10.160 --> 01:11:14.400
looking up for stress management that outperform all the other stress management farmers who
756
01:11:14.400 --> 01:11:20.400
are like with the anias and alphanines all right quick fire this is a game of if this than that
757
01:11:20.960 --> 01:11:31.520
okay so if someone has constant brain fog then if brain fog then alpha g pc and lion's main all
758
01:11:31.520 --> 01:11:38.080
lions main try one or the other or and even higher and probably more beneficial for everything
759
01:11:38.080 --> 01:11:41.840
would be try creatine first before those other creatine because it doesn't help your brain fog it
760
01:11:41.840 --> 01:11:46.080
will help other things that's for sure well and your creatine has so much stuff built into it
761
01:11:46.080 --> 01:11:51.360
that I think that you know you're gonna hit the mark somewhere if someone has low energy but normal
762
01:11:51.360 --> 01:12:00.480
labs then low energy and but normal labs then look to thyroid normal labs would imply normal
763
01:12:00.880 --> 01:12:07.040
yeah yeah I don't know many people who have normal labs that have low energy to be fair so
764
01:12:07.040 --> 01:12:15.040
I would definitely dig dig deeper into thyroid and then I would also look at your organic acids test
765
01:12:15.040 --> 01:12:19.440
do one of them that's not a normal test see where you might a condry or your crypt cycle might be
766
01:12:19.440 --> 01:12:26.400
broken from that cool if someone wants better skin and hair first up a g h k g h k g h k
767
01:12:26.480 --> 01:12:29.920
if someone is dealing with joint pain
768
01:12:31.600 --> 01:12:38.720
sister squadrangularis that one's amazing it's one I actually added to Wolverine because that
769
01:12:38.720 --> 01:12:44.320
was one of those annoying little herbs that was getting kind of comparative compared to like
770
01:12:44.320 --> 01:12:49.520
hyaluronic acid and bpc for how much it helped with recovery and joint pain the other one
771
01:12:49.520 --> 01:12:54.720
that I really like for rheumatoid arthritis is devil's claw that's an amazing herb botanical
772
01:12:54.720 --> 01:13:03.440
for rheumatoid pain and hyaluronic acid too for the lubrication that's awesome stuff
773
01:13:03.440 --> 01:13:07.360
beautiful if someone's overwhelmed with supplements what's your advice to them
774
01:13:08.720 --> 01:13:17.840
just take 50 at once just don't count yeah well just don't count exactly if they're overwhelmed by
775
01:13:17.840 --> 01:13:24.880
it honestly you said it just run through your what you're taking through chat GPT and just say
776
01:13:24.880 --> 01:13:29.840
look I'm there's too many things help me break it down or in lieu of chat GPT and probably a
777
01:13:29.840 --> 01:13:33.840
better option is work with someone who knows what they're doing it's yeah it's so hard to figure it
778
01:13:33.840 --> 01:13:38.240
out yourself I've figured out a lot but I've also worked with a lot of people prior who've helped
779
01:13:38.240 --> 01:13:42.000
me figure it out so there's no shame in asking for help with this stuff it's it's complicated it's
780
01:13:42.480 --> 01:13:47.840
so beautiful if someone wants to invest in one high impact upgrade for their health this year
781
01:13:47.840 --> 01:13:55.200
what would you suggest the just one one money no factor I get a HBOT hey hyperbaric oxygen
782
01:13:55.200 --> 01:14:01.920
I'm so bullish on HBOT at the moment I love them my local gyms just got one so I'm going to be
783
01:14:01.920 --> 01:14:06.320
investing in doing hyperbaric oxygen and you've interviewed scotcher for people who want to
784
01:14:06.320 --> 01:14:10.720
listen more about that I won't even try and attempt to give you one tenth of the information he's
785
01:14:10.720 --> 01:14:16.480
capable of who's there oh scotcher yeah no he's amazing what does the future formulation look
786
01:14:16.480 --> 01:14:21.760
like in the next five to ten years are you working on something that is super exciting too you're
787
01:14:21.760 --> 01:14:26.080
always working on something exciting but working on too many things that that's why I'm working on
788
01:14:26.080 --> 01:14:34.080
a stress formula the future of supplements I believe it will be led by brands like mine and there
789
01:14:34.080 --> 01:14:40.000
are plenty of other ones out there like phone who are doing and spending the money to test their
790
01:14:40.000 --> 01:14:46.160
products and to prove them and our transparent with what they put in it there's too many too many too
791
01:14:46.160 --> 01:14:53.040
many too many brands out there who are not do not care do not test do not prove the purity and
792
01:14:53.040 --> 01:14:57.840
luckily Amazon has started to be aware of that they really copped some bad press over the last
793
01:14:57.840 --> 01:15:02.320
few years for basically buying supplements on there and now that we're getting level up on
794
01:15:02.320 --> 01:15:06.720
now I'm like wow how did all this stuff get past this is really hard to pass these hurdles and
795
01:15:06.720 --> 01:15:12.320
we're already doing very high very high amounts of testing but it's come to the point where you
796
01:15:12.320 --> 01:15:16.960
just there was no hurdle for it you could just sell on it so now we have to test every single
797
01:15:16.960 --> 01:15:22.240
ingredient in every formula get full certificates of analysis like we do a lot of that anyway but for
798
01:15:22.240 --> 01:15:28.480
every ingredient it's not something we've necessarily have to do every time so it's become a lot
799
01:15:28.480 --> 01:15:33.040
more expensive as well which is an unfortunate reality we already expensive and then we've got to
800
01:15:33.040 --> 01:15:39.760
spend like 20,000 dollars testing each product so that's going to be a barrier to it and as
801
01:15:39.760 --> 01:15:47.520
the supplement industry changes I think there'll be a huge discrepancy between the top-end
802
01:15:47.520 --> 01:15:53.200
businesses who've kind of done all of that pre all that expensive work for a long time and then
803
01:15:53.200 --> 01:15:57.520
always fly by night ones who come in and like oh you know it's a billion dollar industry I'm just
804
01:15:57.520 --> 01:16:01.760
going to start making stuff and then they don't realize all of the requirements to it and I think
805
01:16:01.760 --> 01:16:05.440
those requirements are only going to grow not necessarily from government but from these
806
01:16:06.400 --> 01:16:11.120
essential mediums for sale of them so what are you working on that's really exciting you're
807
01:16:11.120 --> 01:16:16.640
right now I'm working on might not excite your audience but I work out a lot I've been work I had
808
01:16:16.640 --> 01:16:21.120
a pre-workout and it was disgusting yeah you ditched it yeah ditched it I've been working on that
809
01:16:21.120 --> 01:16:27.440
for about a year now reformulating it using every single patented material that I possibly could
810
01:16:27.440 --> 01:16:32.000
testing everything and just making the best pre-workout that you can take as a daily even if you
811
01:16:32.000 --> 01:16:39.680
don't work out yeah and what else am I working on a b a b vitamin a daily b with all of the
812
01:16:39.680 --> 01:16:45.040
essentials like the ubiquinoles the coq tens and all of the minerals just something that people
813
01:16:45.040 --> 01:16:49.200
can take daily is like that if you were to take only one thing I'd make it that one you know I
814
01:16:49.200 --> 01:16:53.520
don't like milking formulas and products that people have to take every day but if you're going
815
01:16:53.680 --> 01:16:59.360
if you want to then that one's probably the real foundational one and beyond that I was another 20
816
01:16:59.360 --> 01:17:04.080
or so coming out all right we don't have to list them all you got to keep some stuff secret
817
01:17:04.080 --> 01:17:08.320
are we heading toward a world where people self-experiment too much without understanding the
818
01:17:08.320 --> 01:17:15.200
fundamentals yeah probably TLP ones are definitely evidence of that and I think they're a gateway
819
01:17:15.200 --> 01:17:18.400
drug to the other ones to be honest if people have already gotten over the barrier to entry of
820
01:17:18.400 --> 01:17:24.000
injecting with JLP is more likely to try all the other ones so definitely yeah it's getting there
821
01:17:24.640 --> 01:17:28.560
what's one trend in the health space that excites you and one that concerns you
822
01:17:30.560 --> 01:17:35.200
I'm really liking the extreme influences are starting to be less extreme Brian Johnson's
823
01:17:35.200 --> 01:17:39.600
a really good example of that he's done all the things he's taken the handfuls the supplements
824
01:17:39.600 --> 01:17:44.640
but then he started to look at like meditation and prayer and psychedelics and all these other
825
01:17:44.640 --> 01:17:49.040
things like yeah yeah you getting back in the middle and the center of this whole balance thing
826
01:17:49.040 --> 01:17:52.560
well he was starting to look like he needed to honestly so I'm glad that he's
827
01:17:54.320 --> 01:17:59.360
yeah I definitely think balance is something that never was sexy and never really was click
828
01:17:59.360 --> 01:18:05.680
baby but I'm starting to see that messaging come up through with influences and I think it's just
829
01:18:06.320 --> 01:18:11.840
the the burnout potential for trying to be perfect all the time actually creates the opposite
830
01:18:11.840 --> 01:18:16.000
effect that what you're going for it just doesn't work if you're trying to be perfect all the time so
831
01:18:16.640 --> 01:18:22.800
yeah acceptance of imperfection in biohacking and health this is something I'm actually all for
832
01:18:22.800 --> 01:18:26.960
life life's meant to be lived and if you if you get a 70-sleeve school one day just don't
833
01:18:26.960 --> 01:18:33.680
throw it about it and chuck it chuck a tantrum like some people can get older yeah love it all right
834
01:18:33.680 --> 01:18:38.720
last question my friend if you could remove one piece of bad advice from the health industry entirely
835
01:18:38.800 --> 01:18:45.200
what would it be these chat GPT prompted influences who pretend to be experts that's really annoying
836
01:18:45.200 --> 01:18:51.040
and there's nothing stopping it other than I guess the counter to it is the people who aren't experts
837
01:18:51.040 --> 01:18:57.200
just don't believe everything in influencer myself included if you need to audit what I
838
01:18:57.200 --> 01:19:00.960
please audit what I say to be true before you just go ahead and change your whole life based on it
839
01:19:00.960 --> 01:19:07.280
like I do my best to deliver factual information based on over 10 years of looking into this stuff
840
01:19:07.280 --> 01:19:12.240
versus it's trendy to talk about peptides now and you got an affiliate code to sling in and
841
01:19:12.240 --> 01:19:17.120
sling in some injectables so I'll just get chat GPT or Claude to make a script for me and pretend
842
01:19:17.120 --> 01:19:24.080
I'm an expert at my gripe yeah okay it's a good one it's a really good one all right Kyle van
843
01:19:24.080 --> 01:19:32.240
release tell people where to find you I don't know I'm dead we've been killed by the power to be
844
01:19:32.720 --> 01:19:37.520
social media but I always like the evergreen line our email list is how we're communicating now
845
01:19:37.520 --> 01:19:44.080
considering we are so stifled by meta so media and meta and even Google and all the other ones
846
01:19:44.080 --> 01:19:49.920
don't really like how accessible peptide information is from both our platforms and both our
847
01:19:49.920 --> 01:19:54.640
ourselves so yeah we're level up health calm and you should probably get a pop-up that's
848
01:19:54.640 --> 01:19:58.560
from you to join it that's probably the best way to do it getting on that like that's where we
849
01:19:58.560 --> 01:20:03.040
communicate all the time now and yeah we'll have to figure out some other ways to get the message
850
01:20:03.040 --> 01:20:08.160
out there now that suppression's rampant and are pretty debilitating to the business unfortunately
851
01:20:08.160 --> 01:20:12.240
that's been a challenge over the past few months is when you can't speak and share your message
852
01:20:12.240 --> 01:20:18.000
and your product it does actually affect obviously while the business is doing so it's been a
853
01:20:18.000 --> 01:20:22.960
challenge but yeah getting on that email list is the way that you can support and be informed
854
01:20:22.960 --> 01:20:27.760
of all these new product drops and all the educational stuff that we've been working on for the past
855
01:20:27.760 --> 01:20:34.720
year and all beautiful and folks if you decide to shop while you're you're you're signing up for
856
01:20:34.720 --> 01:20:42.320
the newsletter on the website what's our latest code is it net 10 net 15 net we want you out
857
01:20:42.320 --> 01:20:49.280
from 10 and net 15 or just not one of those are work for sure so net or net 15 and you get to
858
01:20:49.280 --> 01:20:56.080
save 15% off either one thank you so much for all your time and thank you for letting me
859
01:20:56.080 --> 01:21:01.680
ring out your brain today and just pepper you with questions and I'm looking forward actually
860
01:21:01.680 --> 01:21:06.560
looking forward to our next interview which will be for the bioregulator and peptide summit that
861
01:21:06.560 --> 01:21:11.920
comes out in August you actually triggered my response to a previous question black pep is my
862
01:21:11.920 --> 01:21:20.080
crop in the industry I hate that stuff yeah I put you with questions there you go so black pepper
863
01:21:20.560 --> 01:21:27.280
that people use for biotech of ingredients yep yep creates permeability of the garden inhibits
864
01:21:27.280 --> 01:21:34.480
glucoronodation a critical liver detoxification step and on that note and on that note thank you so
865
01:21:34.480 --> 01:21:40.960
much and we'll see you again soon if folks just a quick reminder that all of the information presented
866
01:21:40.960 --> 01:21:48.560
in this podcast is for information purposes only no medical advice no diagnosing no treatments
867
01:21:48.560 --> 01:21:53.520
suggested here before you try anything that you hear about or learn about here make sure that
868
01:21:53.520 --> 01:21:57.120
you check with your medical provider
