OM DENNE EPISODE
Carolina Reis Oliveira’s journey is as impressive as her expertise in skin care. In this episode, she dives deep into the science of skin aging. Along with Dr. Stephanie, she explores and explains both intrinsic and extrinsic factors, from cellular processes to environmental exposures. Carolina also shares insights into inflammation, peptide therapy, and the transformative potential of innovative compounds like OS-01.
OneSkin is getting to the root cause of skin aging with OS-01, a novel peptide that targets cellular senescence. OS1 influences cellular repair pathways and increases epidermal thickness. Explore face and body products at https://www.oneskin.co?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use code BETTER at checkout to save 15%.
Drawing from her team's research, Carolina discusses tangible results in reducing skin aging, offering hope for conditions like hyperpigmentation and rosacea. We explore strategies to stay ahead of the aging curve, aiming for what Carolina calls "escape velocity"—a state where we not only halt aging but reverse its effects.
Episode Overview:
0:00 Intro/Teaser
0:01:29 Interview with Carolina Oliveira
0:03:10 Skin Aging Mechanisms and Peptide Therapy
0:04:28 Intrinsic Mechanisms of Skin Aging
0:08:21 Intrinsic Aging Factors and Genetics
0:10:15 Cellular Senescence and Aging
0:13:11 Autophagy and Aging
0:14:37 Xenomorphic vs. Senolytic Compounds
0:16:18 Discovery of OS1 Peptide
0:19:12 Safety and Validation of OS1 Peptide
0:20:53 Human Clinical Studies on OS1 Peptide
0:25:00 Effects of OS1 on Skin Health
0:29:31 Specific Formulations for Eye Cream
0:31:01 Tailored Skincare for Different Areas of Body
0:36:39 The Science of Hyperpigmentation and Skincare
0:40:14 Combining Acids, Peptides, and Skincare
0:44:15 Consumer Awareness and Integrity in Skincare
0:47:57 The Importance of Antioxidants in Skincare
0:51:52 The Future of Skincare: Lip Treatments
0:53:43 Innovations in Sunscreen Technology
0:56:53 Prioritizing Skin Health Over Immediate Results
0:59:26 Maintaining Integrity in the Skincare Industry
Bio:
Carolina Oliveira, CEO and co-founder of OneSkin. Holds a Ph.D. in stem cell biology and tissue engineering, is a co-inventor of 5 patents and co-author of numerous scientific publications. She relocated from Brazil to Silicon Valley in 2016 to found OneSkin, a fast-growing longevity company developing products to promote skin age reversal by targeting a central driver of aging, the accumulation of senescent cells. Carolina and her team are disrupting the outdated anti-aging skincare industry with their groundbreaking research around skin and longevity.
Resources mentioned:
OneSkin: https://www.oneskin.co/ and use code BETTER at checkout to save 15%.
About Carolina Reis Oliveira, Ph.D.: https://www.oneskin.co/pages/our-story
The science: https://www.oneskin.co/pages/science and https://www.oneskin.co/pages/publications
We are grateful to our sponsors:
EMBR
I absolutely love this for my perimenopausal and menopausal women who are experiencing hot flashes and then the shivering that happens afterward. Go to https://embrlabs.com/products/embr-wave-2?rfsn=7896910.951991&discount/DRSTEPHANIE?redirect=/products/embr-wave-2 and use DRSTEPHANIE for 15% off of the Ember Wave 2. It is a bracelet (I got it in rose gold) and I love it.
FATTY15
Essential fatty acids create better skin, hair, nails, repair age-related damage to cells, and activate pathways that regulate sleep and mood. You can get an additional 15% off of their 90-day subscription starter kit if you go to https://fatty15.com/better and use code BETTER at checkout.
BIOPTIMIZERS
If you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.
****************************
P.S. When you're ready, here are two ways Dr. Stephanie can help you:
Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.
Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results.
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
