Polygenic Risk, Polygenic Scores, Polygenic Indices: What Are They? What Should Be Done with Them?

This episode of the Progress Educational Trust (PET) podcast discusses the science and ethics of PGT-P – a controversial form of preimplantation genetic testing that uses polygenic scores, rather than using more traditional forms of genomic data.

The discussion – which originally took place at the PET Annual Conference – is chaired by Dr Philip Ball (science writer and broadcaster), with contributions from:

⚫ Dr Emma Meaburn (Behavioural Geneticist at Birkbeck University of London)

⚫ Dr Dorit Barlevy (Senior Researcher at Baylor College of Medicine)

⚫ Professor Angus Clarke (Emeritus Professor of Clinical Genetics at Cardiff University)

PET is grateful to the British Fertility Society for supporting this discussion.

PET is also grateful to Jon Nicoll, who created the opening and closing music for its podcast.

Register at https://www.progress.org.uk/events/upcoming-events/ for upcoming PET events.