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[SPEAKER_03]: Hello, and welcome to the C3 Podcast Code Conscious Conversations.
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[SPEAKER_03]: I'm Dr. Lisa Piper, here with Wendy Cona's Born We Are The Founders of Code Health.
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[SPEAKER_02]: Welcome to the C3 Podcast.
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[SPEAKER_02]: Today we are here with our dear friend, Dr. Nathan Brian.
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[SPEAKER_02]: He is an international leader in molecular medicine and nitric oxide biochemistry with over 25 years of research.
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[SPEAKER_02]: He is the founder, chairman, and CEO of Brian Therapeutics Inc., a clinically stage biotechnology company.
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[SPEAKER_02]: with active drug development programs in heart disease, Alzheimer's disease, diabetic ulcers and non-healing wounds.
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[SPEAKER_02]: He also founded Numa Nitric Oxide N101 Nitric Oxide Innovations LLC and Brian Nitracutical's LLC, building a billion dollar enterprise value portfolio.
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[SPEAKER_02]: Dr. Brian was the first scientist to describe nitrite and nitrate as indispensable nutrients and discovered how nitric oxide functions as a critical cellular signaling system.
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[SPEAKER_02]: His patented technology validated in six clinical trials restores the body's natural ability to produce
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[SPEAKER_02]: with out pharmaceutical intervention.
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[SPEAKER_02]: Welcome to the C3 podcast, Dr. Brian.
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[SPEAKER_02]: We are so happy to have you here today.
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[SPEAKER_00]: Linda, Lisa, great to be with you.
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[SPEAKER_00]: And great to see you.
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[SPEAKER_03]: Yeah.
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[SPEAKER_03]: So, you know, we like to start our podcast with a question.
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[SPEAKER_03]: And it's a very special question.
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[SPEAKER_03]: So, tell us, when you hear the word consciousness, what does it mean to you?
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[SPEAKER_03]: And what is one daily habit that helps you stay more conscious in your life, health, or work?
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[SPEAKER_00]: interesting question, you know, consciousness to me means being aware of of your surroundings and and everything that's around you, but I think more as we learn more about this, it's also being aware of things that you otherwise previously weren't aware of because there's so much going on and opening up these neural circuits and understanding and what consciousness is and being able to manifest it and be aware and I think that's how we learn and grow.
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[SPEAKER_00]: And, you know, I've, I've started this, I've been being aware of this for the past couple of years and, you know, I'm a creature of habit, I wake up every morning, do the same things.
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[SPEAKER_00]: But, to answer your question on what I do is, you know, during my 30 minutes in my infrared sauna, I'm meditating, I'm prayer, I'm reading, in prayer, I'm reading scripture, I'm open my Hello app.
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[SPEAKER_00]: But I'm becoming aware and manifesting things and planning my day and you know I got certain things I need to accomplish and how am I going to execute that strategy on a daily basis and I think more importantly is open my mind up to other possibilities.
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[SPEAKER_00]: And I think for me that's what and it's it's really we had a profound effect on my own if and in the success we've had and just being able to see it, plan it and execute these strategies and I think they're so important.
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[SPEAKER_03]: It's so important to be intentional and and then you know, once you set your intention and you put in your effort and you do all your work, it's like the divine grace wants to overflow your life and give you everything your heart desires so it's really beautiful to hear that explanation.
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[SPEAKER_03]: Thank you for sharing.
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[SPEAKER_00]: Yeah, you know, I think it's important to wake up every day with a gratitude because, you know, not every day is promised.
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[SPEAKER_00]: And so to wake up and people to experience this life we have is a blessing each day.
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[SPEAKER_02]: It really is.
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[SPEAKER_02]: Thank you so much for that.
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[SPEAKER_02]: And, you know, talking about gratitude, I'm really just going to say, we are so grateful that we met you and your partners who's in chief for everything that you both are doing is really revolutionary and you are bringing to the world.
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[SPEAKER_02]: The
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[SPEAKER_02]: understanding of what nitric oxide is.
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[SPEAKER_02]: And even before Lisa and I met you, at least for me, I did not even know I heard of nitric oxide.
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[SPEAKER_02]: You talk about it in chemistry class and the compound.
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[SPEAKER_02]: But I thought it was for car racing.
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[SPEAKER_02]: So can you explain to us and our viewers what nitric oxide is and why it is so important for our bodies?
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[SPEAKER_00]: Yeah, I know that that's a foundation of question.
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[SPEAKER_00]: And so nitric oxide is a gas.
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[SPEAKER_00]: It's what we call a signaling molecule.
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[SPEAKER_00]: It's naturally produced in the human body.
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[SPEAKER_00]: We're finding that the order we get the less we make and that's what's responsible for age-related chronic disease.
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[SPEAKER_00]: But when you understand, again, it once it's produced it's gone in less than a second.
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[SPEAKER_00]: And that's been the challenge on developing not only diagnostics, but also safe and effective drug therapy and product technology, because how do you deliver a gas in a product technology that's going in less than a second?
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[SPEAKER_00]: So what we had to do and I did this 25 years ago was when nitric oxide is produced, where does it go, what does it become and how does it signal?
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[SPEAKER_00]: And so that was my early work in academia, published over 100 peer-reviewed papers, kind of on that subject matter, but it dilates blood vessels, right?
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[SPEAKER_00]: So it's improved oxygen delivery and delivery of oxygen by hemoglobin.
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[SPEAKER_00]: It mobilizes our own stem cells.
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[SPEAKER_00]: It activates our mitochondria, the energy producing organelles of the cell.
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[SPEAKER_00]: It prevents, it activates an enzyme called telomerase and prevents the ends of our telomerase and chromosomes from getting shorter.
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[SPEAKER_00]: But I think in terms of mitigating chronic disease, it completely inhibits inflammation, it reduces oxidative stress, and it cracks the immune dysfunction that we see in chronic disease.
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[SPEAKER_00]: So when you look at chronic age-related disease, whether it's cardiovascular disease, Alzheimer's, diabetes, autoimmune disease,
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[SPEAKER_00]: There's always four underlying kind of common denominators.
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[SPEAKER_00]: There's always reduced blood flow.
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[SPEAKER_00]: There's runaway inflammation, excessive oxidative stress, and then immune dysfunction.
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[SPEAKER_00]: In nitric oxide, the deficiency of nitric oxide is what leads to all of this.
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[SPEAKER_00]: Now, if we can restore and recapitulate nitric oxide production and signaling, you basically address the root cause of all age-related chronic disease.
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[SPEAKER_00]: And so that's why this is so foundational in why these conversations are so important because, you know, you guys are perfectly simple, very well-informed, highly educated, but yet you didn't know about this very important topic in health and longevity.
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[SPEAKER_02]: That's right.
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[SPEAKER_02]: Yeah.
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[SPEAKER_02]: That's right.
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[SPEAKER_02]: And so, you know, we are fans of everything that you manufacture, as a matter of fact, at least, and I both take the laws in every day, two times a day, we use, I love the serum.
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[SPEAKER_02]: And that is actually how I learned about how the product worked.
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[SPEAKER_02]: because of that very simple, you know, demonstration that when the serum is put on a hand and you rub it into the hand, it changes color because the blood is flowing to that area.
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[SPEAKER_02]: And it was really at that moment that I thought to myself, well, if a drop of this nitric oxide serum is able to do that and it changes the color of the skin tone,
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[SPEAKER_02]: then what must it possibly do it be doing when you're taking it internally through the lozange.
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[SPEAKER_02]: So I'm just going to hold it up, but we have, you know, our podcast is audio, but we also sometimes show it.
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[SPEAKER_02]: So this is what it looks like and it's a simple lozange and it actually tastes really good.
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[SPEAKER_02]: And Lisa and we both keep it on our desk.
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[SPEAKER_02]: And so I guess by explaining what you did in the technology to get the nitric oxide in this lozenge, and then for it to work and to be stable, that is really what is and what you've done in a pioneering fashion.
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[SPEAKER_02]: And you know what?
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[SPEAKER_02]: Right?
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[UNKNOWN]: Yeah.
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[SPEAKER_00]: Now, like, I mean, how many products out there that people take that are sold and marketed, you can demonstrate an immediate effect, especially in skin care.
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[SPEAKER_00]: I mean, there's a lot of faith, hope, and really a lot of deception that occurs in marketing with a lot of products.
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[SPEAKER_00]: But, you know, nitric oxide, such a potent molecule, if your products produce it and release it, you see the effects.
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[SPEAKER_00]: Your body always responds to nitric oxide.
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[SPEAKER_00]: So the innovations on this was we had to figure out how do we make a shell stable form of nitric oxide gas?
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[SPEAKER_00]: So in the serum, we have to create two separate chambers to keep the active separate.
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[SPEAKER_00]: Then when you put the active skitties in right and left, and then the law's in, yeah, the same thing.
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[SPEAKER_00]: So there's a spatial random distribution of active in that law's.
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[SPEAKER_00]: And when you put it in your mouth, it's matrix falls apart and we start to produce nitric oxide gas.
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[SPEAKER_00]: So everything we do is predicate it on the fact that if your body can't make nitric oxide.
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[SPEAKER_00]: because of whatever reason that you live a poor diet, you have an unhealthy lifestyle.
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[SPEAKER_00]: Then we have to do it for you.
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[SPEAKER_00]: But if you're about to can make testosterone or women can make estrogen, then we have to give it to you.
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[SPEAKER_00]: Same thing with nitric oxide.
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[SPEAKER_00]: If you're about to can't produce nitric oxide, taking precursors, substrates, beat powder, originates.
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[SPEAKER_00]: doesn't work.
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[SPEAKER_00]: The reason you're deficient is your body's unable to utilize that.
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[SPEAKER_00]: So it's completely different way of thinking that, you know, because I spent 25 years in academia and science, I understand the biochemistry.
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[SPEAKER_00]: All these other companies out there are just marketing heads.
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[SPEAKER_00]: They have no idea about the science, and so they really have no business creating product technology in a field in which they don't understand.
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[SPEAKER_02]: I'd like to ask you a question.
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[SPEAKER_02]: So if someone, how would someone know if they were deficient in nitric oxide?
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[SPEAKER_00]: Now, look, it's a great question.
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[SPEAKER_00]: We've been trying to answer for 25 years.
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[SPEAKER_00]: And unfortunately, if you go to your doctor, primary care doc, and they do blood draw, it's not part of the standard labs.
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[SPEAKER_00]: And as you girls know, and conventional medicine, doctors think if you can't measure, it's not important.
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[SPEAKER_00]: So, something most important things for our health and wellness are not measured, whether it's energy and electron flow and conductance or nitric oxide.
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[SPEAKER_00]: That's the foundation for health.
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[SPEAKER_00]: So we understand today there's a hierarchy of symptoms that develop when your body gradually loses it's ability to make nitric oxide.
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[SPEAKER_00]: So number one, usually the first sign in symptom is a rectal dysfunction.
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[SPEAKER_00]: And again, this isn't just in men, this is in women.
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[SPEAKER_00]: We have to have an increase in blood flow to the sex organs in order from indigated interaction, from women to get interaction and women to have an organism.
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[SPEAKER_00]: So if you can't make nitric oxide, you can't dilate the blood vessels of sex organs that we call that rectal dysfunction.
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[SPEAKER_00]: Number two, your blood pressure starts to go up, because if you lose the main phase of dildectory molecule in hydrochoxide, your blood vessels constrict and you get the same volume of blood going through smaller pipes, simple laws of physics tell us pressure has to go up.
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[SPEAKER_00]: And two out of three Americans have an unsafe elevation of blood pressure.
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[SPEAKER_00]: Number three, you develop metabolic disease and insulin resistance.
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[SPEAKER_00]: In 2011, we published that nitric oxide is the pindor.
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[SPEAKER_00]: Insulin signaling is dependent upon nitric oxide production.
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[SPEAKER_00]: So insulin resistance is a symptom of nitric oxide deficiency.
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[SPEAKER_00]: And we now know that more than 90% of Americans are metabolically unfit.
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[SPEAKER_00]: Number four, you start to develop exercise intolerance.
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[SPEAKER_00]: So if you can't go out and walk briskly or walk up a five-step without getting short and breath and tightness in your chest,
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[SPEAKER_00]: then your nitric oxide deficient.
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[SPEAKER_00]: And then fifthly, which is kind of the latest stage, is you start to get brain fog, what we call mod cognitive impairment, vasculine mentioned, and eventually Alzheimer's.
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[SPEAKER_02]: I think these are all things that are so prevalent in most people.
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[SPEAKER_02]: And wouldn't it be incredible if the knowledge was out there and the information was received in a way where people just,
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[SPEAKER_02]: had the understanding that there could be this one simple molecule that they could be taking that could be preventative to so many things.
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[SPEAKER_00]: Yeah, that's our goal is to take it because look, you cannot ignore the data in the summit.
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[SPEAKER_00]: There's over 200,000 publications in the scientific literature on the effects of nitric oxide.
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[SPEAKER_00]: So my goal is to educate and form on the science and inform people, stop doing the things that we know are inhibiting the natural production of nitric oxide, and then start doing the things that you can naturally do to increase its production.
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[SPEAKER_00]: And then remarkably, and we've been doing this for a couple of decades now, blood pressure normalizes sexual function improves cognition improves human performance improves.
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[SPEAKER_00]: People can get off prescription medication for their blood pressure, for their diabetes, all these things.
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[SPEAKER_00]: And so it's the way medicine should be to get to the root cause.
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[SPEAKER_00]: And you know, I think even maybe hypocrisy said at the honours of years ago, that the physician of the future will prescribe no medications.
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[SPEAKER_00]: We've gotten so far away from that original principles of applied physiology in medicine.
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[SPEAKER_00]: And now it's applied pharmacology in medicine and look, it's making no one better right with a sickest people in the earth.
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[SPEAKER_00]: This is all we talk about.
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[SPEAKER_03]: So why do you think nitric oxide levels are depleted worldwide and what factors are interfering with the body's natural ability to produce it?
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[SPEAKER_00]: Well, there are a number of things.
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[SPEAKER_00]: We first had to understand how the human body makes nitric oxide.
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[SPEAKER_00]: We now understand both of those pathways.
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[SPEAKER_00]: There's an enzyme that becomes dysfunctional and then we have bacteria that live in and on our body that are naturally producing nitric oxide.
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[SPEAKER_00]: So, number one, it's the sedentary lifestyle.
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[SPEAKER_00]: We have to exercise if we don't exercise or not activating stimulating nitric oxide production.
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[SPEAKER_00]: Number two, the diet, especially the Western diet, things high in sugar, simple carbohydrates.
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[SPEAKER_00]: Anything that causes an increase in blood sugar,
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[SPEAKER_00]: both changes the oral microbiome and it sticks to the enzymes of sugar and glucose is sticky.
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[SPEAKER_00]: And it sticks to protein, sticks to enzymes, it sticks to hemoglobin.
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[SPEAKER_00]: And we can measure that and we call that hemoglobin A1C.
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[SPEAKER_00]: And so the sugar also sticks to other enzymes like the nitric oxide synthics.
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[SPEAKER_00]: In enzymes and biochemistry have to undergo conformational changes to train for these electrons.
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[SPEAKER_00]: But if glucose and glue is glued together, can't do its job.
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[SPEAKER_00]: So that's the biggest issue is a high sugar, high carbohydrate diet.
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[SPEAKER_00]: And then things like when we're looking at the microbiome, things like antiseptics.
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[SPEAKER_00]: mouthwash.
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[SPEAKER_00]: Two out of three Americans used mouthwash every day and two out of three Americans have a nice evaluation of blood pressure.
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[SPEAKER_00]: Number the big one is fluoride, you know, fluoride in toothpaste, fluoride in drinking water, they put fluoride in toothpaste in drinking water because it kills bacteria.
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[SPEAKER_00]: So when you bathe in it, it kills the bacteria on your skin.
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[SPEAKER_00]: When you drink it, it kills the bacteria in your gut.
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[SPEAKER_00]: When you brush with fluoride toothpaste, it completely sterilizes your mouth, causes dyspiosis.
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[SPEAKER_00]: And now we know that microbial dyspiosis is associated with every single chronic disease in humans.
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[SPEAKER_00]: So now we know antibiotics and overusing antibiotics.
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[SPEAKER_00]: Do you go to the doctor?
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[SPEAKER_00]: Do you get a viral infection?
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[SPEAKER_00]: They won't get it via antibiotics.
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[SPEAKER_00]: I mean, it makes no sense.
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[SPEAKER_00]: And then, you know, the other thing is proton pump inhibitors are anacids.
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[SPEAKER_00]: These drugs completely shut down nitric oxide production.
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[SPEAKER_00]: In the US, there were 200 million prescriptions written every year for anacids.
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[SPEAKER_00]: And now we're finding that two out of three Americans use anacids every day, even without a prescription because these are now over the camera drugs.
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[SPEAKER_00]: And the data are clear that people who have been using proton pump inhibitors for at least three years,
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[SPEAKER_00]: have a 40% greater incidence of heart attack stroke and Alzheimer's.
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[SPEAKER_00]: And you can explain that observation because it's completely inhibiting nitric oxide production.
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[SPEAKER_00]: And yet everybody's on these drugs.
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[SPEAKER_00]: You don't even have to have a prescription from and they're very they're not only dangerous.
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[SPEAKER_00]: They're deadly.
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[SPEAKER_03]: They think their doctor is the smarter than them.
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[SPEAKER_03]: They're not.
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[SPEAKER_03]: This isn't, you know, this hasn't become mainstream, so there's people like you, what you're doing, educating people, bringing it to their awareness, I think that's really what's been lacking, I mean, not drop if he used to be the natural way to do medicine and, you know,
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[SPEAKER_03]: Symptom management came a business of a greedy business at that Yeah, there's no money in cures right as we all know.
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[SPEAKER_00]: Yeah, there's money in treatment chronic treatment chronic They found it is the best in the history of the world at getting a customer keeping that cut for the rest of their life And it's it's a great financial model for those companies, but it's at the expense of our own health
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[SPEAKER_02]: You know, with code health, what we have as you know is an alternative to the over the counter in prescription medication.
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[SPEAKER_02]: And everyone asks us, do you have something that we could take instead of an an acid?
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[SPEAKER_02]: Do you have something for digestive issues?
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[SPEAKER_02]: And when we look into the future of our next formula, that is really where we're going because of the need for that.
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[SPEAKER_02]: And you mentioned something else, and I just want to touch upon it, and that is the oral microbiome, because besides,
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[SPEAKER_02]: the nitric oxide lozenge that you have and the skin care, you have a toothpaste and you are creating a mouthwash and we here, you know, Lisa and I here.
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[SPEAKER_02]: the importance of no fluoride and also the antiseptic aspect of it.
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[SPEAKER_02]: You can't kill all of the bacteria because you need those bacteria for certain things.
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[SPEAKER_02]: But you just said something that I didn't even know that it affects the nitric oxide.
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[SPEAKER_02]: So even something like that.
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[SPEAKER_02]: I just learned from you and the importance of not killing, you know, all of the bacteria on your body, we're all used to hand sanitizers and everything, you know, disinfecting things and whatnot and here it is, where it's the nitric oxide that is being depleted.
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[SPEAKER_00]: Yeah.
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[SPEAKER_00]: Now look, it wears me out.
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[SPEAKER_00]: I get on a plane every week and they're still given these anti-bacterial hand wipes.
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[SPEAKER_00]: And it's, it's look, there's no physician in the world.
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[SPEAKER_00]: I can tell you a story that would tell you it's a good idea to take an antibiotic every day for the rest of your life.
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[SPEAKER_00]: Because we know that, you know, a hundred years ago when this was discovered, we didn't know that there was a microbiome.
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[SPEAKER_00]: We thought all bacteria was bad.
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[SPEAKER_00]: Not today.
19:32.934 --> 19:35.918
[SPEAKER_00]: We know humans are 10 times more bacterial than we are humans.
19:35.898 --> 19:43.208
[SPEAKER_00]: So we have to support these bacteria resigned in and on our body to do important things and we as humans can't do and we kill them to our own demise.
19:43.849 --> 19:52.842
[SPEAKER_00]: So what we're finding is, and this was data from probably almost 30 years ago, that if you take, if you eradicate the bacteria, and we were part of some of these studies.
19:52.882 --> 19:57.949
[SPEAKER_00]: So we took, we found that people who have high blood pressure had the least diverse oral microbiome.
19:57.989 --> 20:05.820
[SPEAKER_00]: We published that in 2010, 2011, and then so that wasn't what we call association, right?
20:05.800 --> 20:14.748
[SPEAKER_00]: So then we did another study, we took normal tinted patients that had healthy blood pressure did a four oral exam period exam, and then we gave them mouth wash for seven days.
20:15.109 --> 20:21.795
[SPEAKER_00]: Twice a day for seven days, brought them back, did tongue scrapings, analyzed the bacteria, and then monitored blood pressure.
20:22.375 --> 20:26.779
[SPEAKER_00]: And what we found was these people had normal blood pressure, just simply giving mouth wash.
20:27.000 --> 20:32.905
[SPEAKER_00]: In some people, we saw a 26 millimeter increase in blood pressure in seven days.
20:33.087 --> 20:37.912
[SPEAKER_00]: So that's called, it's completely eradicating the nitric oxide producing bacteria.
20:38.593 --> 20:45.219
[SPEAKER_00]: So if you use mouthwash, you're killing the nitric oxide producing bacteria, your blood pressure goes up, you lose the cardiovascular benefits of exercise.
20:46.020 --> 20:55.189
[SPEAKER_00]: And it's a slippery slope to chronic disease because eye blood pressure is the number one driver of the number one killer of the mening women worldwide, which is cardiovascular disease.
20:55.209 --> 20:57.412
[SPEAKER_00]: So then the thought was, okay, how do we correct this?
20:58.413 --> 21:01.896
[SPEAKER_00]: And I've known about the dangers of fluoride for probably less 30 years.
21:01.994 --> 21:05.079
[SPEAKER_00]: Because Florence and Nero toxin, it lowers IQ and kids.
21:05.119 --> 21:07.362
[SPEAKER_00]: It's an antiseptic and it shuts down your thyroid function.
21:07.522 --> 21:11.308
[SPEAKER_00]: I mean, there's no way people should be using fluoride these days.
21:12.169 --> 21:22.264
[SPEAKER_00]: So I was looking for fluoride free toothpaste, but you know, I've been using these for 25, 30 years, but there were other things in there that were still detrimental to the oral microbiome.
21:22.244 --> 21:28.631
[SPEAKER_00]: It's like, okay, now we understand the ecologist, these bacteria, we've analyzed them, we've cultured them, we understand what they like.
21:28.671 --> 21:38.422
[SPEAKER_00]: Let's create a toothpaste in an oral line of products where we can support the oral microbiome, we can create an environment that's conducive to their growth and population.
21:39.223 --> 21:47.813
[SPEAKER_00]: And so that was the toothpaste, the cardiovascular smart toothpaste, hydroxy appetite base fluoride-free, we could prebiotics in there and completely change the ecology.
21:47.793 --> 22:02.454
[SPEAKER_00]: And now we're finding, so the next question was, if we take people with high blood pressure, that are non-responsive to anti-hypertensive therapy, which is 50% of population, and we target that oral microbiome, improve their nitric oxide production, can we bring their blood pressure down?
22:03.576 --> 22:05.599
[SPEAKER_00]: And the answer is remarkably yes.
22:06.490 --> 22:08.435
[SPEAKER_00]: and think about the global impact of that.
22:09.216 --> 22:18.959
[SPEAKER_00]: If you can change your oral hygienic practices, give me the fluoride, start using our toothpaste, target the oral microbiome, improve nitric oxide production, blood pressure comes down.
22:19.681 --> 22:25.174
[SPEAKER_00]: And high-predict, cardiovascular disease has been the number one killer of minimum from more than 100 years.
22:25.154 --> 22:26.457
[SPEAKER_00]: and it's not getting any better.
22:26.657 --> 22:27.739
[SPEAKER_00]: So I see the future.
22:27.759 --> 22:35.957
[SPEAKER_00]: I see us finally reducing addressing cardiovascular disease where it's no longer the number one killer because we know how to diagnose it.
22:36.317 --> 22:37.199
[SPEAKER_00]: We know what causes it.
22:37.279 --> 22:38.522
[SPEAKER_00]: We know how to treat it.
22:38.705 --> 22:56.578
[SPEAKER_00]: And then, you know, for those people who like to use a mouth wrench, which is two out of three Americans, we now have an obligation because we know better to give them an alternative to the antiseptics, where you can use a mouth wrench, support the microbiome, improve nitric oxide production, and actually improve your systemic health.
22:56.778 --> 23:04.171
[SPEAKER_00]: So this is going to be a game changer because and you're not everybody's looking for nitric oxide products, but everybody, well, hopefully everybody brushes their teeth every day.
23:04.712 --> 23:07.256
[SPEAKER_00]: And we know that two out of three Americans use mouthwash every day.
23:08.018 --> 23:12.205
[SPEAKER_00]: So let's give them a healthy alternative that's going to improve their health rather than make them sick.
23:13.484 --> 23:15.206
[SPEAKER_02]: Absolutely fantastic.
23:15.226 --> 23:25.640
[SPEAKER_02]: Yeah, it's absolutely fantastic because you know, it's exactly what you said and you hope, but let's just say everyone brushes their teeth, right?
23:27.843 --> 23:31.027
[SPEAKER_02]: So and and two times a day, AM and PM.
23:31.588 --> 23:35.273
[SPEAKER_02]: So just by changing your toothpaste.
23:36.215 --> 23:58.240
[SPEAKER_02]: which you're doing anyway, you're brushing your teeth, you're doing so many other positive things for your body and your system on a molecular level on a cellular level, which is preventative, and that's the angle, but how come so many dentists
23:58.220 --> 24:03.167
[SPEAKER_02]: are still giving out samples of toothpaste with fluoride.
24:03.567 --> 24:07.392
[SPEAKER_02]: I mean, this, this is not even being talked about.
24:08.394 --> 24:09.335
[SPEAKER_03]: It's their habit.
24:09.355 --> 24:10.216
[SPEAKER_03]: It's what they know.
24:10.236 --> 24:11.077
[SPEAKER_03]: It's what they do.
24:11.177 --> 24:13.621
[SPEAKER_03]: It's the companies that provide them with the samples.
24:14.502 --> 24:15.764
[SPEAKER_00]: And it's still fine.
24:16.004 --> 24:18.748
[SPEAKER_00]: It's, it's, it's Heather train, but we're making headway.
24:19.248 --> 24:22.793
[SPEAKER_00]: You know, I spoke in Chicago before the American Civil Association,
24:22.773 --> 24:43.431
[SPEAKER_00]: Last year maybe maybe a couple of years ago, but we're finally getting their attention because as you girls know the systemic health begins in the mouth And so we have to get rid of fluoride the risk benefit analysis on fluoride the jury's in there is no benefit and it's it's it's all risk and that's an easy quote You just eliminate your exposure to fluoride
24:44.778 --> 24:51.589
[SPEAKER_00]: But then, you know, we have to start understanding how to not just because like oral pathogens are bad, right?
24:51.609 --> 24:57.278
[SPEAKER_00]: We know there's translocation, a oral bacteria that can cause systemic inflammation and it caused plaque rupture and heart attack and it's true.
24:57.899 --> 25:05.571
[SPEAKER_00]: So the challenge in the dental community is how do you address the oral pathogens without throwing an atomic bomb in the mix and killing everything?
25:06.142 --> 25:16.838
[SPEAKER_00]: And so that's what we're coming in because what we're finding is that nitric oxide, pathogenes are selected or sensitive to nitric oxide, with a non-pathogenic commensals make nitric oxide.
25:17.759 --> 25:30.217
[SPEAKER_00]: So if you restore nitric oxide production or in the best examples the lawzons, we generate nitric oxide gas in the oral cavity, it's selectively kills the oral pathogens and it improves the diversity of the oral microbiome.
25:30.237 --> 25:33.482
[SPEAKER_00]: So just using what we're
25:33.462 --> 25:41.218
[SPEAKER_00]: You know, at the very minimum is going to dramatically transform your health because it's going to improve nitric oxide production.
25:41.238 --> 25:49.395
[SPEAKER_00]: It's going to recouple the enzyme and the lining of the blood vessels and it's going to restore the oral microbiome and improve the natural production of nitric oxide.
25:50.624 --> 26:10.782
[SPEAKER_02]: See, so even something like that, I take the laws and now I'm understanding even more so that by keeping the laws in my mouth and having it, you know, dissipate or dissolve in my mouth, that's adding another benefit to my entire system.
26:10.802 --> 26:14.986
[SPEAKER_00]: So that's how we designed that laws into like that because here's what I wanna do.
26:15.006 --> 26:18.589
[SPEAKER_00]: I never wanna give the body something that it's not used to see.
26:18.839 --> 26:26.701
[SPEAKER_00]: So we had to do a little bit of mathematics, but I understand how much nitric oxide gas is produced in a 24-hour period under optimal conditions.
26:27.303 --> 26:34.603
[SPEAKER_00]: Through dye and through the oral microbiome, through secretion of stomach acid, and through this enzyme nitric oxide synthase.
26:34.685 --> 26:42.698
[SPEAKER_00]: Then we had to do some calculations on how much of that is disturbed or missing in the American population, the global population.
26:43.399 --> 26:47.846
[SPEAKER_00]: And then to develop a dietary supplement, it's meant to supplement what's missing, right?
26:48.026 --> 26:53.976
[SPEAKER_00]: And so that's what we do in supplements, drug therapy is completely different, it's just average safety and efficacy.
26:53.956 --> 26:55.480
[SPEAKER_00]: So we want to create the delta.
26:55.981 --> 27:02.398
[SPEAKER_00]: But again, nitric oxide is a gas and we try to mimic the flux and rates of production that would normally occur.
27:03.020 --> 27:09.737
[SPEAKER_00]: So we had to design this only disintegrating tablet that releases a certain amount of nitric oxide over a certain period of time.
27:09.717 --> 27:20.595
[SPEAKER_00]: because you don't want to hit the system with a bolus of nitric oxide that would completely dilate all the blood vessels lead to a loss of blood pressure, profusion and then people get lightheaded, syncopy and pass out.
27:20.635 --> 27:22.899
[SPEAKER_00]: We have to slowly titrate this in.
27:22.939 --> 27:27.207
[SPEAKER_00]: So this laws and is designed to dissolve over five to six, seven minutes.
27:28.048 --> 27:32.215
[SPEAKER_00]: And so you just move it in your mouth and it's slowly dissolved with its releasing nitric oxide.
27:32.195 --> 27:34.418
[SPEAKER_00]: But it's changing the environment in the oral cavity.
27:34.438 --> 27:35.299
[SPEAKER_00]: It's vasoactive.
27:35.319 --> 27:38.263
[SPEAKER_00]: We see dilation of your crotties within 10 or 12 seconds.
27:38.924 --> 27:42.810
[SPEAKER_00]: We see a 20% improvement into the little nitric oxide production within 20 minutes.
27:43.330 --> 27:48.478
[SPEAKER_00]: You know, sexual function improves blood pressure, normalizes, increased number of stem cells in circulation.
27:48.518 --> 27:55.367
[SPEAKER_00]: Everything that nitric oxide is known to do, the law's inch does itself because it's producing nitric oxide.
27:56.073 --> 28:02.500
[SPEAKER_03]: You know, what you're doing sounds like in a different way because you're using actual ingredients.
28:03.101 --> 28:08.347
[SPEAKER_03]: But it sounds like this is very similar to what we do and it's information medicine.
28:08.827 --> 28:15.475
[SPEAKER_03]: You're feeling the body by restoring cellular signals or cellular communication without the chemicals.
28:16.476 --> 28:21.642
[SPEAKER_03]: So why are all the signals getting disrupted to begin with?
28:22.178 --> 28:29.345
[SPEAKER_00]: like there's so many disruptors in the environment in which we live, whether it's 5G or electromagnetic frequencies.
28:29.365 --> 28:35.772
[SPEAKER_00]: And you know, one of molecular, kind of a atomic scale, we have to, you know, there's all this energy flow.
28:35.792 --> 28:38.455
[SPEAKER_00]: There's electron flow and, you know, there's conductance.
28:38.515 --> 28:42.499
[SPEAKER_00]: You know, and, you know, we diagnose death by loss of electrical activity.
28:42.880 --> 28:47.224
[SPEAKER_00]: But, you know, humans aren't like a light switch where you turn it on and off or we're batteries.
28:47.204 --> 28:50.150
[SPEAKER_00]: And so, you know, in your fly side, if you're better, you get slow, you're like this.
28:50.771 --> 28:52.796
[SPEAKER_00]: And our light dims, right?
28:53.277 --> 28:54.800
[SPEAKER_00]: And our body always talks to us.
28:54.880 --> 28:59.871
[SPEAKER_00]: And that dimming of the light and the loss of electrical activity shows up as erectile dysfunction.
28:59.891 --> 29:03.458
[SPEAKER_00]: High blood pressure, autoimmune disease, illness, or disease.
29:03.438 --> 29:18.198
[SPEAKER_00]: And so we've got to get back to the fundamentals and restore these these circuits, the information, whether it's, you know, the nervous system and nerve conductance or whether it's the cardiovascular system delivering oxygen nutrients to every organ tissue and cell on the body.
29:18.599 --> 29:19.660
[SPEAKER_00]: I mean, that's where it all starts.
29:19.700 --> 29:24.687
[SPEAKER_00]: But as you say, we have to restore the flow of information and restore normal signaling.
29:24.667 --> 29:32.658
[SPEAKER_00]: in the signal transduction because since the outside environment can then change the expression of genes and proteins to adapt to that new environment.
29:33.079 --> 29:37.365
[SPEAKER_00]: But that's information that signal transduction that's lost in almost every disease.
29:37.385 --> 29:50.083
[SPEAKER_00]: So if we can restore that through through the code type technology or just improving nitric oxide and circulation and blood flow
29:50.654 --> 30:10.030
[SPEAKER_03]: Does it help people detox also like say you have sluggish blood and your lymphatic system isn't really draining because like you said you're living a sedentary life or you're not exercising enough for all these environmental toxins and pollutants stress poor diet all these factors.
30:10.010 --> 30:16.762
[SPEAKER_00]: For sure, the purpose of the cardiovascular system is to deliver and oxygen nutrients to cells and then take out the waste products.
30:17.443 --> 30:22.792
[SPEAKER_00]: If you compromise and you have poor blood flow, poor circulation, poor vascular health, then neither that's happening.
30:22.812 --> 30:30.125
[SPEAKER_00]: You're not getting nutrients to cells and then they're building this metabolic waste products and then these cells become toxic and dysfunctional.
30:30.145 --> 30:33.891
[SPEAKER_00]: So we got to get the good stuff in, we got to take out the bad stuff.
30:33.871 --> 30:45.207
[SPEAKER_00]: And that occurs both in the cardiovascular system, the lymphatic system, the lymphatics, have their own endothelial cells that produce nitric oxide that kind of control lymphatic flow and, you know, they're removal of toxins.
30:45.908 --> 30:58.967
[SPEAKER_00]: But yeah, it's all we call foundational, you know, but there are also other things you have to incorporate in this, you know, nitric oxide is not a silver bullet, it's foundational, but it's not going to fix everything that's wrong with everyone, you still have to address other problems.
30:59.048 --> 31:13.729
[SPEAKER_03]: But do you find in your work that like we find in hours when you decrease stress in the body seemingly unrelated things resolve so when you restore this nitric oxide in the body do you find that seemingly unrelated issues resolve.
31:15.492 --> 31:17.715
[SPEAKER_00]: Yeah, we did there's a lot of things together.
31:18.151 --> 31:31.789
[SPEAKER_00]: Look, the body is an intricate system of different networks and organ systems, but what we find is that if you restore blood flow and improve oxygen delivery and mobilize stem cells and activate mitochondria, every cell in the body works.
31:32.670 --> 31:46.808
[SPEAKER_00]: But again, if you're not good at dealing with stress and you've got you know, sympathetic overdrive and dysautonomium, you still have to correct that, you know, because even though we're increasing blood flow, if you're not good at dealing with stress,
31:47.075 --> 32:03.058
[SPEAKER_00]: Well, what I've learned is, and this took me some time because there's, you know, we live in a stressful environment, a lot of stressful things happen to us, but, you know, I've just made it kind of a practice that I don't worry about anything I can't control, I can't control it, I don't worry about.
32:03.393 --> 32:11.606
[SPEAKER_00]: And when you start to think about it, how much can we actually control zero really little so you know what I don't worry about anything I wake up every morning with gratitude with the servant's hard.
32:11.626 --> 32:19.379
[SPEAKER_00]: I want to go out and do the best I can control what I can help and I don't stress there's cannot stress me and I've made it a practice.
32:20.882 --> 32:23.305
[SPEAKER_02]: That is the best advice.
32:23.967 --> 32:26.110
[SPEAKER_02]: Yeah, that you could give someone.
32:26.562 --> 32:51.169
[SPEAKER_02]: because when you're able to really remove yourself from that and realize you can't control anything, except for what you do and you have that power of knowing that, living that, breathing that, it changes your entire perspective on the way that you handle everything, everything.
32:52.043 --> 32:52.785
[SPEAKER_02]: takes a lot.
32:53.045 --> 32:55.209
[SPEAKER_02]: I mean, it takes a lot to be able to do that.
32:55.851 --> 32:57.915
[SPEAKER_02]: But it's practice.
32:58.015 --> 32:59.198
[SPEAKER_02]: It's mindfulness.
32:59.538 --> 33:02.504
[SPEAKER_02]: And that's what Lisa and I talk about all the time.
33:02.544 --> 33:04.088
[SPEAKER_02]: It's mindfulness.
33:04.749 --> 33:11.723
[SPEAKER_02]: Back to the original question of consciousness and how it's all interconnected.
33:11.703 --> 33:12.584
[SPEAKER_00]: For sure.
33:13.265 --> 33:38.571
[SPEAKER_00]: Yeah, and I like that's why I like hanging out with with with with you guys and like minded people who Who see the importance of intention and consciousness and manifesting things whether it's in our personal life from our professional life and you know We got a red red ourselves of people who are energy Steelers and who want to steal your dreams and tell you what you're doing It's impossible or stupid and it's never gonna work and you know, I just don't a lot of
33:38.551 --> 33:42.616
[SPEAKER_00]: You know, again, this has been a process of a journey that you have to eliminate those people.
33:42.716 --> 33:46.741
[SPEAKER_00]: And you know, as we all know, you, you are who you're surround yourself with.
33:46.761 --> 33:47.001
[SPEAKER_00]: Right.
33:47.342 --> 33:54.510
[SPEAKER_00]: Your stuff is so, you know, I'm very picky about who I allow into my space and, you know, my inner circle.
33:54.830 --> 34:02.740
[SPEAKER_00]: Because I've, you know, I've been around toxic people and, you know, get in business with a lot of toxic people that, you know, try to destroy my life.
34:02.760 --> 34:05.203
[SPEAKER_00]: And if I would have let them, they would have been successful.
34:05.263 --> 34:07.005
[SPEAKER_00]: But that's not happening anymore.
34:07.323 --> 34:08.486
[SPEAKER_02]: Yeah, I love that.
34:08.506 --> 34:12.336
[SPEAKER_02]: Well, thank you for allowing us to be in part of your inner circle.
34:12.356 --> 34:14.743
[SPEAKER_02]: We love that part of the heart inner circle.
34:14.803 --> 34:23.847
[SPEAKER_02]: And we do, we just cannot say enough about what you and Susan are doing.
34:23.827 --> 34:40.148
[SPEAKER_02]: Um, it is so important for people to really understand and I say this with with true integrity and a full heart really, there are so many products that are out there and it doesn't matter what.
34:40.128 --> 34:42.871
[SPEAKER_02]: supplement, or you can have anything out there.
34:42.911 --> 34:52.462
[SPEAKER_02]: There are great quality companies, and then there are just companies that are just trying to make a quick buck, and they're not doing it the right way.
34:53.063 --> 35:09.662
[SPEAKER_02]: And Lisa and I can really say you are doing it the right way, the research, the technology that has gone into this, even for someone to understand that there are so many other nitric
35:10.098 --> 35:13.054
[SPEAKER_02]: but if it's not being released.
35:13.507 --> 35:19.172
[SPEAKER_02]: in the proper way, it could literally be so damaging to an individual.
35:19.212 --> 35:40.712
[SPEAKER_02]: So just for our viewers and for the audience just really before, you know, not just with Dr. Nathan's N101 products, but with everything that you are looking to use, it is so important to know and understand what you are actually putting on and in your body.
35:40.692 --> 35:57.799
[SPEAKER_02]: because that one thing that you think is doing good for you because, you know, an influencer set it or because it's less expensive than something else can be doing the most harm and just thank you.
35:58.140 --> 36:07.915
[SPEAKER_00]: Thank you for saying because there's so many consumers are confused because I
36:07.895 --> 36:12.438
[SPEAKER_00]: And that's one of the biggest fraudulent, deceptive marketing campaigns out there.
36:12.458 --> 36:13.785
[SPEAKER_00]: Beats are not nitric oxide.
36:13.805 --> 36:16.096
[SPEAKER_00]: You don't get nitric oxide from the eats.
36:16.157 --> 36:16.639
[SPEAKER_00]: And so,
36:16.940 --> 36:18.743
[SPEAKER_00]: You know, there's, you met a good point.
36:18.763 --> 36:20.886
[SPEAKER_00]: There are a lot of good companies out there still in a lot of good products.
36:20.987 --> 36:24.593
[SPEAKER_00]: But this isn't a vitamin C or vitamin D. You could throw in a capsule.
36:24.613 --> 36:25.975
[SPEAKER_00]: This is nitric oxide gas.
36:26.636 --> 36:30.022
[SPEAKER_00]: And I just simply asked if you trust us as your nitric oxide product.
36:30.042 --> 36:34.970
[SPEAKER_00]: Because we spent the time in the lab doing the research, understanding the biochemistry and physiology.
36:35.651 --> 36:41.901
[SPEAKER_00]: And all these other companies out there, they just want your money, they're trying to sell you a bill of goods, and they don't understand the science.
36:42.151 --> 36:49.020
[SPEAKER_00]: and the people, the companies who spend the most on advertising, obviously have the poorest sites to keep that in mind.
36:49.040 --> 36:49.660
[SPEAKER_02]: Very true.
36:50.121 --> 36:56.689
[SPEAKER_03]: I will say Wendy, yeah, I do have one more question because I know our time is coming to the end.
36:56.909 --> 37:03.418
[SPEAKER_03]: And you did discuss that the mouthwash is coming out soon, but give us the inside scoop.
37:03.458 --> 37:04.819
[SPEAKER_03]: What else is in the pipeline?
37:05.040 --> 37:07.703
[SPEAKER_03]: What are you moving towards in the future?
37:07.683 --> 37:10.828
[SPEAKER_00]: Like we have grant expectations and we're on a mission.
37:11.148 --> 37:15.134
[SPEAKER_00]: So we're going to, you know, we've got a supplement line and additional line.
37:15.855 --> 37:19.360
[SPEAKER_00]: We've got the skin care line with clean skin care line of products.
37:19.400 --> 37:21.724
[SPEAKER_00]: The N101 we're building out an oral line of products.
37:21.764 --> 37:24.688
[SPEAKER_00]: The toothpaste and the mouth rinse called breath of life.
37:25.329 --> 37:29.235
[SPEAKER_00]: You know, we're moving into animals for pets, you know, because.
37:29.215 --> 37:55.240
[SPEAKER_00]: You know, they're mammals as well and need nitric oxide, and so, you know, on several third-brad race horses, we're improving performance in our third-brad horses and, you know, preventing pulmonary beliefs, but so we'll move into veterinary space and then, you know, we're developing our drug therapy, where, you know, my goal was to develop dietary supplements, I could say that my goal was to understand the mechanism of disease to the extent we could develop rational drug therapy.
37:55.220 --> 37:57.483
[SPEAKER_00]: So we're moving our drug therapy through clinical trials.
37:57.523 --> 37:58.825
[SPEAKER_00]: I've got a drug for heart disease.
37:58.945 --> 37:59.926
[SPEAKER_00]: We mentioned the introduction.
37:59.966 --> 38:05.313
[SPEAKER_00]: We're making a drug for Alzheimer's, which, you know, I'm convinced we'll completely eradicate Alzheimer's and dementia.
38:05.894 --> 38:08.918
[SPEAKER_00]: And then we're making a topical drug for diabetic ulcers and non-healing wounds.
38:08.978 --> 38:10.420
[SPEAKER_00]: But those three are the beginning.
38:10.480 --> 38:13.924
[SPEAKER_00]: But, you know, we'll continue to develop drug therapy for things like heart failure.
38:13.944 --> 38:17.609
[SPEAKER_00]: You know, nitric oxide is extremely important for pulmonary infections.
38:18.250 --> 38:21.514
[SPEAKER_00]: And for things like migraines and acne.
38:21.494 --> 38:28.744
[SPEAKER_00]: What we're finding is there's not a single indication or nitric oxide at the right dose at the right time in the right patient, would not be beneficial.
38:28.764 --> 38:34.331
[SPEAKER_00]: So my job is to create the technology that addresses specific needs for specific indications.
38:34.712 --> 38:43.924
[SPEAKER_00]: It's not only safe, but effective without chemicals, synthetic compounds, as basically restorative physiology, given the body back what it needs so the body can heal.
38:44.579 --> 38:54.594
[SPEAKER_03]: love it and it's very synergistic with with what we do as well and a lot of the things that you mentioned sounds like very similar things that we have in our pipeline.
38:54.674 --> 39:07.212
[SPEAKER_02]: So I want to
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[SPEAKER_00]: Well, first, I will shamelessly plug my latest book called the Secret of Nitrocoxide, bring the science to life.
39:13.483 --> 39:23.565
[SPEAKER_00]: This tells the story of Nitrocoxide, but also my personal journey of discovering the kind of my early, early years and then through academia and then what led to the development of our product technology.
39:23.585 --> 39:25.048
[SPEAKER_00]: But yeah, it's a great thing.
39:25.028 --> 39:27.411
[SPEAKER_00]: Amazon Barnes and Noble Nathan's book.com.
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[SPEAKER_00]: There's a link, I encourage people to follow and subscribe to my YouTube channel, Dr. Nathan S. Brian, nitric oxide, my Instagram, Dr. Nathan S. Brian, same on LinkedIn, X, Dr. Nitric, and for those interested in our products, it's in101.com.
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[SPEAKER_00]: That's the letter
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[SPEAKER_03]: perfect.
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[SPEAKER_03]: Thank you so much for being with us today.
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[SPEAKER_03]: We really enjoyed this code conscious conversation.
39:57.301 --> 40:00.672
[SPEAKER_00]: We need to thank so much and look forward to seeing you soon.
41:25.921 --> 41:39.880
[SPEAKER_01]: Unconventionly dare to explore Breaking barriers open indoors With every step they lie the way I need
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[SPEAKER_01]: One mission, lighting away, transforming the future with love every day With science and spirit, their journey unfolds Restoring balance as the future unfolds
00:09.413 --> 00:14.726
[SPEAKER_03]: Hello, and welcome to the C3 Podcast Code Conscious Conversations.
00:15.006 --> 00:20.419
[SPEAKER_03]: I'm Dr. Lisa Piper, here with Wendy Cona's Born We Are The Founders of Code Health.
00:43.163 --> 00:45.427
[SPEAKER_02]: Welcome to the C3 Podcast.
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[SPEAKER_02]: Today we are here with our dear friend, Dr. Nathan Brian.
00:50.475 --> 00:58.748
[SPEAKER_02]: He is an international leader in molecular medicine and nitric oxide biochemistry with over 25 years of research.
00:59.309 --> 01:08.243
[SPEAKER_02]: He is the founder, chairman, and CEO of Brian Therapeutics Inc., a clinically stage biotechnology company.
01:08.223 --> 01:16.238
[SPEAKER_02]: with active drug development programs in heart disease, Alzheimer's disease, diabetic ulcers and non-healing wounds.
01:16.859 --> 01:31.547
[SPEAKER_02]: He also founded Numa Nitric Oxide N101 Nitric Oxide Innovations LLC and Brian Nitracutical's LLC, building a billion dollar enterprise value portfolio.
01:31.527 --> 01:45.481
[SPEAKER_02]: Dr. Brian was the first scientist to describe nitrite and nitrate as indispensable nutrients and discovered how nitric oxide functions as a critical cellular signaling system.
01:46.041 --> 01:59.695
[SPEAKER_02]: His patented technology validated in six clinical trials restores the body's natural ability to produce
01:59.675 --> 02:02.058
[SPEAKER_02]: with out pharmaceutical intervention.
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[SPEAKER_02]: Welcome to the C3 podcast, Dr. Brian.
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[SPEAKER_02]: We are so happy to have you here today.
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[SPEAKER_00]: Linda, Lisa, great to be with you.
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[SPEAKER_00]: And great to see you.
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[SPEAKER_03]: Yeah.
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[SPEAKER_03]: So, you know, we like to start our podcast with a question.
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[SPEAKER_03]: And it's a very special question.
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[SPEAKER_03]: So, tell us, when you hear the word consciousness, what does it mean to you?
02:23.021 --> 02:28.888
[SPEAKER_03]: And what is one daily habit that helps you stay more conscious in your life, health, or work?
02:29.189 --> 02:54.589
[SPEAKER_00]: interesting question, you know, consciousness to me means being aware of of your surroundings and and everything that's around you, but I think more as we learn more about this, it's also being aware of things that you otherwise previously weren't aware of because there's so much going on and opening up these neural circuits and understanding and what consciousness is and being able to manifest it and be aware and I think that's how we learn and grow.
02:54.940 --> 03:02.896
[SPEAKER_00]: And, you know, I've, I've started this, I've been being aware of this for the past couple of years and, you know, I'm a creature of habit, I wake up every morning, do the same things.
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[SPEAKER_00]: But, to answer your question on what I do is, you know, during my 30 minutes in my infrared sauna, I'm meditating, I'm prayer, I'm reading, in prayer, I'm reading scripture, I'm open my Hello app.
03:15.460 --> 03:29.220
[SPEAKER_00]: But I'm becoming aware and manifesting things and planning my day and you know I got certain things I need to accomplish and how am I going to execute that strategy on a daily basis and I think more importantly is open my mind up to other possibilities.
03:30.062 --> 03:41.198
[SPEAKER_00]: And I think for me that's what and it's it's really we had a profound effect on my own if and in the success we've had and just being able to see it, plan it and execute these strategies and I think they're so important.
03:41.785 --> 04:01.221
[SPEAKER_03]: It's so important to be intentional and and then you know, once you set your intention and you put in your effort and you do all your work, it's like the divine grace wants to overflow your life and give you everything your heart desires so it's really beautiful to hear that explanation.
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[SPEAKER_03]: Thank you for sharing.
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[SPEAKER_00]: Yeah, you know, I think it's important to wake up every day with a gratitude because, you know, not every day is promised.
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[SPEAKER_00]: And so to wake up and people to experience this life we have is a blessing each day.
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[SPEAKER_02]: It really is.
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[SPEAKER_02]: Thank you so much for that.
04:15.108 --> 04:35.430
[SPEAKER_02]: And, you know, talking about gratitude, I'm really just going to say, we are so grateful that we met you and your partners who's in chief for everything that you both are doing is really revolutionary and you are bringing to the world.
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[SPEAKER_02]: The
04:37.152 --> 04:40.881
[SPEAKER_02]: understanding of what nitric oxide is.
04:40.941 --> 04:48.478
[SPEAKER_02]: And even before Lisa and I met you, at least for me, I did not even know I heard of nitric oxide.
04:48.498 --> 04:52.708
[SPEAKER_02]: You talk about it in chemistry class and the compound.
04:53.229 --> 04:55.735
[SPEAKER_02]: But I thought it was for car racing.
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[SPEAKER_02]: So can you explain to us and our viewers what nitric oxide is and why it is so important for our bodies?
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[SPEAKER_00]: Yeah, I know that that's a foundation of question.
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[SPEAKER_00]: And so nitric oxide is a gas.
05:16.276 --> 05:17.679
[SPEAKER_00]: It's what we call a signaling molecule.
05:17.739 --> 05:20.305
[SPEAKER_00]: It's naturally produced in the human body.
05:20.946 --> 05:25.996
[SPEAKER_00]: We're finding that the order we get the less we make and that's what's responsible for age-related chronic disease.
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[SPEAKER_00]: But when you understand, again, it once it's produced it's gone in less than a second.
05:31.220 --> 05:43.238
[SPEAKER_00]: And that's been the challenge on developing not only diagnostics, but also safe and effective drug therapy and product technology, because how do you deliver a gas in a product technology that's going in less than a second?
05:43.842 --> 05:51.472
[SPEAKER_00]: So what we had to do and I did this 25 years ago was when nitric oxide is produced, where does it go, what does it become and how does it signal?
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[SPEAKER_00]: And so that was my early work in academia, published over 100 peer-reviewed papers, kind of on that subject matter, but it dilates blood vessels, right?
05:59.462 --> 06:03.927
[SPEAKER_00]: So it's improved oxygen delivery and delivery of oxygen by hemoglobin.
06:03.947 --> 06:05.569
[SPEAKER_00]: It mobilizes our own stem cells.
06:06.210 --> 06:10.035
[SPEAKER_00]: It activates our mitochondria, the energy producing organelles of the cell.
06:10.015 --> 06:16.225
[SPEAKER_00]: It prevents, it activates an enzyme called telomerase and prevents the ends of our telomerase and chromosomes from getting shorter.
06:16.967 --> 06:27.665
[SPEAKER_00]: But I think in terms of mitigating chronic disease, it completely inhibits inflammation, it reduces oxidative stress, and it cracks the immune dysfunction that we see in chronic disease.
06:27.685 --> 06:33.795
[SPEAKER_00]: So when you look at chronic age-related disease, whether it's cardiovascular disease, Alzheimer's, diabetes, autoimmune disease,
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[SPEAKER_00]: There's always four underlying kind of common denominators.
06:37.064 --> 06:38.367
[SPEAKER_00]: There's always reduced blood flow.
06:39.029 --> 06:43.841
[SPEAKER_00]: There's runaway inflammation, excessive oxidative stress, and then immune dysfunction.
06:44.623 --> 06:49.135
[SPEAKER_00]: In nitric oxide, the deficiency of nitric oxide is what leads to all of this.
06:49.688 --> 06:58.345
[SPEAKER_00]: Now, if we can restore and recapitulate nitric oxide production and signaling, you basically address the root cause of all age-related chronic disease.
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[SPEAKER_00]: And so that's why this is so foundational in why these conversations are so important because, you know, you guys are perfectly simple, very well-informed, highly educated, but yet you didn't know about this very important topic in health and longevity.
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[SPEAKER_02]: That's right.
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[SPEAKER_02]: Yeah.
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[SPEAKER_02]: That's right.
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[SPEAKER_02]: And so, you know, we are fans of everything that you manufacture, as a matter of fact, at least, and I both take the laws in every day, two times a day, we use, I love the serum.
07:32.138 --> 07:36.823
[SPEAKER_02]: And that is actually how I learned about how the product worked.
07:36.803 --> 07:50.316
[SPEAKER_02]: because of that very simple, you know, demonstration that when the serum is put on a hand and you rub it into the hand, it changes color because the blood is flowing to that area.
07:50.897 --> 08:03.469
[SPEAKER_02]: And it was really at that moment that I thought to myself, well, if a drop of this nitric oxide serum is able to do that and it changes the color of the skin tone,
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[SPEAKER_02]: then what must it possibly do it be doing when you're taking it internally through the lozange.
08:11.320 --> 08:18.050
[SPEAKER_02]: So I'm just going to hold it up, but we have, you know, our podcast is audio, but we also sometimes show it.
08:18.170 --> 08:25.982
[SPEAKER_02]: So this is what it looks like and it's a simple lozange and it actually tastes really good.
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[SPEAKER_02]: And Lisa and we both keep it on our desk.
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[SPEAKER_02]: And so I guess by explaining what you did in the technology to get the nitric oxide in this lozenge, and then for it to work and to be stable, that is really what is and what you've done in a pioneering fashion.
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[SPEAKER_02]: And you know what?
08:54.682 --> 08:54.962
[SPEAKER_02]: Right?
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[UNKNOWN]: Yeah.
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[SPEAKER_00]: Now, like, I mean, how many products out there that people take that are sold and marketed, you can demonstrate an immediate effect, especially in skin care.
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[SPEAKER_00]: I mean, there's a lot of faith, hope, and really a lot of deception that occurs in marketing with a lot of products.
09:11.892 --> 09:17.919
[SPEAKER_00]: But, you know, nitric oxide, such a potent molecule, if your products produce it and release it, you see the effects.
09:17.939 --> 09:20.402
[SPEAKER_00]: Your body always responds to nitric oxide.
09:20.787 --> 09:27.878
[SPEAKER_00]: So the innovations on this was we had to figure out how do we make a shell stable form of nitric oxide gas?
09:27.942 --> 09:33.067
[SPEAKER_00]: So in the serum, we have to create two separate chambers to keep the active separate.
09:33.087 --> 09:37.432
[SPEAKER_00]: Then when you put the active skitties in right and left, and then the law's in, yeah, the same thing.
09:37.452 --> 09:41.156
[SPEAKER_00]: So there's a spatial random distribution of active in that law's.
09:41.176 --> 09:45.841
[SPEAKER_00]: And when you put it in your mouth, it's matrix falls apart and we start to produce nitric oxide gas.
09:45.941 --> 09:51.587
[SPEAKER_00]: So everything we do is predicate it on the fact that if your body can't make nitric oxide.
09:51.955 --> 09:56.164
[SPEAKER_00]: because of whatever reason that you live a poor diet, you have an unhealthy lifestyle.
09:56.685 --> 09:58.308
[SPEAKER_00]: Then we have to do it for you.
09:58.328 --> 10:03.018
[SPEAKER_00]: But if you're about to can make testosterone or women can make estrogen, then we have to give it to you.
10:03.419 --> 10:04.461
[SPEAKER_00]: Same thing with nitric oxide.
10:04.482 --> 10:10.875
[SPEAKER_00]: If you're about to can't produce nitric oxide, taking precursors, substrates, beat powder, originates.
10:10.855 --> 10:11.716
[SPEAKER_00]: doesn't work.
10:11.876 --> 10:14.620
[SPEAKER_00]: The reason you're deficient is your body's unable to utilize that.
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[SPEAKER_00]: So it's completely different way of thinking that, you know, because I spent 25 years in academia and science, I understand the biochemistry.
10:23.131 --> 10:26.095
[SPEAKER_00]: All these other companies out there are just marketing heads.
10:26.475 --> 10:33.825
[SPEAKER_00]: They have no idea about the science, and so they really have no business creating product technology in a field in which they don't understand.
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[SPEAKER_02]: I'd like to ask you a question.
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[SPEAKER_02]: So if someone, how would someone know if they were deficient in nitric oxide?
10:41.703 --> 10:42.845
[SPEAKER_00]: Now, look, it's a great question.
10:42.885 --> 10:44.567
[SPEAKER_00]: We've been trying to answer for 25 years.
10:44.607 --> 10:51.396
[SPEAKER_00]: And unfortunately, if you go to your doctor, primary care doc, and they do blood draw, it's not part of the standard labs.
10:51.456 --> 10:56.563
[SPEAKER_00]: And as you girls know, and conventional medicine, doctors think if you can't measure, it's not important.
10:57.083 --> 11:06.876
[SPEAKER_00]: So, something most important things for our health and wellness are not measured, whether it's energy and electron flow and conductance or nitric oxide.
11:07.437 --> 11:11.322
[SPEAKER_00]: That's the foundation for health.
11:11.707 --> 11:18.278
[SPEAKER_00]: So we understand today there's a hierarchy of symptoms that develop when your body gradually loses it's ability to make nitric oxide.
11:18.939 --> 11:22.144
[SPEAKER_00]: So number one, usually the first sign in symptom is a rectal dysfunction.
11:22.164 --> 11:24.909
[SPEAKER_00]: And again, this isn't just in men, this is in women.
11:24.949 --> 11:32.301
[SPEAKER_00]: We have to have an increase in blood flow to the sex organs in order from indigated interaction, from women to get interaction and women to have an organism.
11:32.321 --> 11:37.630
[SPEAKER_00]: So if you can't make nitric oxide, you can't dilate the blood vessels of sex organs that we call that rectal dysfunction.
11:37.610 --> 11:50.758
[SPEAKER_00]: Number two, your blood pressure starts to go up, because if you lose the main phase of dildectory molecule in hydrochoxide, your blood vessels constrict and you get the same volume of blood going through smaller pipes, simple laws of physics tell us pressure has to go up.
11:51.279 --> 11:53.965
[SPEAKER_00]: And two out of three Americans have an unsafe elevation of blood pressure.
11:53.945 --> 11:57.630
[SPEAKER_00]: Number three, you develop metabolic disease and insulin resistance.
11:57.650 --> 12:00.594
[SPEAKER_00]: In 2011, we published that nitric oxide is the pindor.
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[SPEAKER_00]: Insulin signaling is dependent upon nitric oxide production.
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[SPEAKER_00]: So insulin resistance is a symptom of nitric oxide deficiency.
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[SPEAKER_00]: And we now know that more than 90% of Americans are metabolically unfit.
12:11.809 --> 12:14.172
[SPEAKER_00]: Number four, you start to develop exercise intolerance.
12:14.192 --> 12:21.302
[SPEAKER_00]: So if you can't go out and walk briskly or walk up a five-step without getting short and breath and tightness in your chest,
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[SPEAKER_00]: then your nitric oxide deficient.
12:23.124 --> 12:31.652
[SPEAKER_00]: And then fifthly, which is kind of the latest stage, is you start to get brain fog, what we call mod cognitive impairment, vasculine mentioned, and eventually Alzheimer's.
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[SPEAKER_02]: I think these are all things that are so prevalent in most people.
12:39.480 --> 12:47.948
[SPEAKER_02]: And wouldn't it be incredible if the knowledge was out there and the information was received in a way where people just,
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[SPEAKER_02]: had the understanding that there could be this one simple molecule that they could be taking that could be preventative to so many things.
13:00.550 --> 13:07.118
[SPEAKER_00]: Yeah, that's our goal is to take it because look, you cannot ignore the data in the summit.
13:07.699 --> 13:12.986
[SPEAKER_00]: There's over 200,000 publications in the scientific literature on the effects of nitric oxide.
13:13.627 --> 13:27.064
[SPEAKER_00]: So my goal is to educate and form on the science and inform people, stop doing the things that we know are inhibiting the natural production of nitric oxide, and then start doing the things that you can naturally do to increase its production.
13:27.044 --> 13:36.420
[SPEAKER_00]: And then remarkably, and we've been doing this for a couple of decades now, blood pressure normalizes sexual function improves cognition improves human performance improves.
13:36.860 --> 13:41.248
[SPEAKER_00]: People can get off prescription medication for their blood pressure, for their diabetes, all these things.
13:41.288 --> 13:45.375
[SPEAKER_00]: And so it's the way medicine should be to get to the root cause.
13:45.795 --> 13:53.288
[SPEAKER_00]: And you know, I think even maybe hypocrisy said at the honours of years ago, that the physician of the future will prescribe no medications.
13:53.268 --> 14:00.998
[SPEAKER_00]: We've gotten so far away from that original principles of applied physiology in medicine.
14:01.038 --> 14:07.567
[SPEAKER_00]: And now it's applied pharmacology in medicine and look, it's making no one better right with a sickest people in the earth.
14:07.888 --> 14:10.912
[SPEAKER_00]: This is all we talk about.
14:10.932 --> 14:19.984
[SPEAKER_03]: So why do you think nitric oxide levels are depleted worldwide and what factors are interfering with the body's natural ability to produce it?
14:21.297 --> 14:22.319
[SPEAKER_00]: Well, there are a number of things.
14:22.519 --> 14:25.764
[SPEAKER_00]: We first had to understand how the human body makes nitric oxide.
14:25.824 --> 14:27.687
[SPEAKER_00]: We now understand both of those pathways.
14:27.707 --> 14:33.556
[SPEAKER_00]: There's an enzyme that becomes dysfunctional and then we have bacteria that live in and on our body that are naturally producing nitric oxide.
14:34.077 --> 14:36.080
[SPEAKER_00]: So, number one, it's the sedentary lifestyle.
14:36.301 --> 14:41.128
[SPEAKER_00]: We have to exercise if we don't exercise or not activating stimulating nitric oxide production.
14:41.689 --> 14:46.577
[SPEAKER_00]: Number two, the diet, especially the Western diet, things high in sugar, simple carbohydrates.
14:46.637 --> 14:49.161
[SPEAKER_00]: Anything that causes an increase in blood sugar,
14:49.141 --> 14:54.952
[SPEAKER_00]: both changes the oral microbiome and it sticks to the enzymes of sugar and glucose is sticky.
14:55.332 --> 14:58.398
[SPEAKER_00]: And it sticks to protein, sticks to enzymes, it sticks to hemoglobin.
14:58.719 --> 15:00.963
[SPEAKER_00]: And we can measure that and we call that hemoglobin A1C.
15:01.364 --> 15:05.952
[SPEAKER_00]: And so the sugar also sticks to other enzymes like the nitric oxide synthics.
15:05.932 --> 15:10.781
[SPEAKER_00]: In enzymes and biochemistry have to undergo conformational changes to train for these electrons.
15:11.282 --> 15:15.811
[SPEAKER_00]: But if glucose and glue is glued together, can't do its job.
15:15.831 --> 15:19.899
[SPEAKER_00]: So that's the biggest issue is a high sugar, high carbohydrate diet.
15:20.580 --> 15:25.189
[SPEAKER_00]: And then things like when we're looking at the microbiome, things like antiseptics.
15:25.169 --> 15:26.512
[SPEAKER_00]: mouthwash.
15:26.532 --> 15:30.723
[SPEAKER_00]: Two out of three Americans used mouthwash every day and two out of three Americans have a nice evaluation of blood pressure.
15:31.525 --> 15:40.647
[SPEAKER_00]: Number the big one is fluoride, you know, fluoride in toothpaste, fluoride in drinking water, they put fluoride in toothpaste in drinking water because it kills bacteria.
15:41.032 --> 15:43.394
[SPEAKER_00]: So when you bathe in it, it kills the bacteria on your skin.
15:43.454 --> 15:45.336
[SPEAKER_00]: When you drink it, it kills the bacteria in your gut.
15:46.578 --> 15:51.663
[SPEAKER_00]: When you brush with fluoride toothpaste, it completely sterilizes your mouth, causes dyspiosis.
15:51.723 --> 15:57.769
[SPEAKER_00]: And now we know that microbial dyspiosis is associated with every single chronic disease in humans.
15:58.910 --> 16:02.333
[SPEAKER_00]: So now we know antibiotics and overusing antibiotics.
16:02.954 --> 16:03.835
[SPEAKER_00]: Do you go to the doctor?
16:03.855 --> 16:05.016
[SPEAKER_00]: Do you get a viral infection?
16:05.036 --> 16:06.037
[SPEAKER_00]: They won't get it via antibiotics.
16:06.417 --> 16:08.119
[SPEAKER_00]: I mean, it makes no sense.
16:09.213 --> 16:13.260
[SPEAKER_00]: And then, you know, the other thing is proton pump inhibitors are anacids.
16:13.641 --> 16:16.946
[SPEAKER_00]: These drugs completely shut down nitric oxide production.
16:16.966 --> 16:21.554
[SPEAKER_00]: In the US, there were 200 million prescriptions written every year for anacids.
16:21.574 --> 16:28.606
[SPEAKER_00]: And now we're finding that two out of three Americans use anacids every day, even without a prescription because these are now over the camera drugs.
16:28.686 --> 16:34.596
[SPEAKER_00]: And the data are clear that people who have been using proton pump inhibitors for at least three years,
16:34.576 --> 16:38.002
[SPEAKER_00]: have a 40% greater incidence of heart attack stroke and Alzheimer's.
16:38.663 --> 16:43.531
[SPEAKER_00]: And you can explain that observation because it's completely inhibiting nitric oxide production.
16:43.551 --> 16:44.993
[SPEAKER_00]: And yet everybody's on these drugs.
16:45.174 --> 16:48.219
[SPEAKER_00]: You don't even have to have a prescription from and they're very they're not only dangerous.
16:48.259 --> 16:48.840
[SPEAKER_00]: They're deadly.
16:49.621 --> 16:52.907
[SPEAKER_03]: They think their doctor is the smarter than them.
16:53.287 --> 16:54.289
[SPEAKER_03]: They're not.
16:54.269 --> 17:12.345
[SPEAKER_03]: This isn't, you know, this hasn't become mainstream, so there's people like you, what you're doing, educating people, bringing it to their awareness, I think that's really what's been lacking, I mean, not drop if he used to be the natural way to do medicine and, you know,
17:12.325 --> 17:21.375
[SPEAKER_03]: Symptom management came a business of a greedy business at that Yeah, there's no money in cures right as we all know.
17:21.395 --> 17:36.392
[SPEAKER_00]: Yeah, there's money in treatment chronic treatment chronic They found it is the best in the history of the world at getting a customer keeping that cut for the rest of their life And it's it's a great financial model for those companies, but it's at the expense of our own health
17:36.659 --> 17:43.952
[SPEAKER_02]: You know, with code health, what we have as you know is an alternative to the over the counter in prescription medication.
17:44.573 --> 17:50.441
[SPEAKER_02]: And everyone asks us, do you have something that we could take instead of an an acid?
17:50.601 --> 17:52.484
[SPEAKER_02]: Do you have something for digestive issues?
17:53.205 --> 18:02.998
[SPEAKER_02]: And when we look into the future of our next formula, that is really where we're going because of the need for that.
18:03.679 --> 18:10.969
[SPEAKER_02]: And you mentioned something else, and I just want to touch upon it, and that is the oral microbiome, because besides,
18:10.949 --> 18:26.882
[SPEAKER_02]: the nitric oxide lozenge that you have and the skin care, you have a toothpaste and you are creating a mouthwash and we here, you know, Lisa and I here.
18:27.166 --> 18:34.094
[SPEAKER_02]: the importance of no fluoride and also the antiseptic aspect of it.
18:34.174 --> 18:40.062
[SPEAKER_02]: You can't kill all of the bacteria because you need those bacteria for certain things.
18:40.642 --> 18:45.849
[SPEAKER_02]: But you just said something that I didn't even know that it affects the nitric oxide.
18:46.589 --> 18:48.752
[SPEAKER_02]: So even something like that.
18:48.732 --> 19:07.838
[SPEAKER_02]: I just learned from you and the importance of not killing, you know, all of the bacteria on your body, we're all used to hand sanitizers and everything, you know, disinfecting things and whatnot and here it is, where it's the nitric oxide that is being depleted.
19:08.425 --> 19:08.725
[SPEAKER_00]: Yeah.
19:09.246 --> 19:10.167
[SPEAKER_00]: Now look, it wears me out.
19:10.207 --> 19:15.033
[SPEAKER_00]: I get on a plane every week and they're still given these anti-bacterial hand wipes.
19:15.854 --> 19:19.138
[SPEAKER_00]: And it's, it's look, there's no physician in the world.
19:20.079 --> 19:25.025
[SPEAKER_00]: I can tell you a story that would tell you it's a good idea to take an antibiotic every day for the rest of your life.
19:25.425 --> 19:30.111
[SPEAKER_00]: Because we know that, you know, a hundred years ago when this was discovered, we didn't know that there was a microbiome.
19:30.151 --> 19:32.314
[SPEAKER_00]: We thought all bacteria was bad.
19:32.414 --> 19:32.874
[SPEAKER_00]: Not today.
19:32.934 --> 19:35.918
[SPEAKER_00]: We know humans are 10 times more bacterial than we are humans.
19:35.898 --> 19:43.208
[SPEAKER_00]: So we have to support these bacteria resigned in and on our body to do important things and we as humans can't do and we kill them to our own demise.
19:43.849 --> 19:52.842
[SPEAKER_00]: So what we're finding is, and this was data from probably almost 30 years ago, that if you take, if you eradicate the bacteria, and we were part of some of these studies.
19:52.882 --> 19:57.949
[SPEAKER_00]: So we took, we found that people who have high blood pressure had the least diverse oral microbiome.
19:57.989 --> 20:05.820
[SPEAKER_00]: We published that in 2010, 2011, and then so that wasn't what we call association, right?
20:05.800 --> 20:14.748
[SPEAKER_00]: So then we did another study, we took normal tinted patients that had healthy blood pressure did a four oral exam period exam, and then we gave them mouth wash for seven days.
20:15.109 --> 20:21.795
[SPEAKER_00]: Twice a day for seven days, brought them back, did tongue scrapings, analyzed the bacteria, and then monitored blood pressure.
20:22.375 --> 20:26.779
[SPEAKER_00]: And what we found was these people had normal blood pressure, just simply giving mouth wash.
20:27.000 --> 20:32.905
[SPEAKER_00]: In some people, we saw a 26 millimeter increase in blood pressure in seven days.
20:33.087 --> 20:37.912
[SPEAKER_00]: So that's called, it's completely eradicating the nitric oxide producing bacteria.
20:38.593 --> 20:45.219
[SPEAKER_00]: So if you use mouthwash, you're killing the nitric oxide producing bacteria, your blood pressure goes up, you lose the cardiovascular benefits of exercise.
20:46.020 --> 20:55.189
[SPEAKER_00]: And it's a slippery slope to chronic disease because eye blood pressure is the number one driver of the number one killer of the mening women worldwide, which is cardiovascular disease.
20:55.209 --> 20:57.412
[SPEAKER_00]: So then the thought was, okay, how do we correct this?
20:58.413 --> 21:01.896
[SPEAKER_00]: And I've known about the dangers of fluoride for probably less 30 years.
21:01.994 --> 21:05.079
[SPEAKER_00]: Because Florence and Nero toxin, it lowers IQ and kids.
21:05.119 --> 21:07.362
[SPEAKER_00]: It's an antiseptic and it shuts down your thyroid function.
21:07.522 --> 21:11.308
[SPEAKER_00]: I mean, there's no way people should be using fluoride these days.
21:12.169 --> 21:22.264
[SPEAKER_00]: So I was looking for fluoride free toothpaste, but you know, I've been using these for 25, 30 years, but there were other things in there that were still detrimental to the oral microbiome.
21:22.244 --> 21:28.631
[SPEAKER_00]: It's like, okay, now we understand the ecologist, these bacteria, we've analyzed them, we've cultured them, we understand what they like.
21:28.671 --> 21:38.422
[SPEAKER_00]: Let's create a toothpaste in an oral line of products where we can support the oral microbiome, we can create an environment that's conducive to their growth and population.
21:39.223 --> 21:47.813
[SPEAKER_00]: And so that was the toothpaste, the cardiovascular smart toothpaste, hydroxy appetite base fluoride-free, we could prebiotics in there and completely change the ecology.
21:47.793 --> 22:02.454
[SPEAKER_00]: And now we're finding, so the next question was, if we take people with high blood pressure, that are non-responsive to anti-hypertensive therapy, which is 50% of population, and we target that oral microbiome, improve their nitric oxide production, can we bring their blood pressure down?
22:03.576 --> 22:05.599
[SPEAKER_00]: And the answer is remarkably yes.
22:06.490 --> 22:08.435
[SPEAKER_00]: and think about the global impact of that.
22:09.216 --> 22:18.959
[SPEAKER_00]: If you can change your oral hygienic practices, give me the fluoride, start using our toothpaste, target the oral microbiome, improve nitric oxide production, blood pressure comes down.
22:19.681 --> 22:25.174
[SPEAKER_00]: And high-predict, cardiovascular disease has been the number one killer of minimum from more than 100 years.
22:25.154 --> 22:26.457
[SPEAKER_00]: and it's not getting any better.
22:26.657 --> 22:27.739
[SPEAKER_00]: So I see the future.
22:27.759 --> 22:35.957
[SPEAKER_00]: I see us finally reducing addressing cardiovascular disease where it's no longer the number one killer because we know how to diagnose it.
22:36.317 --> 22:37.199
[SPEAKER_00]: We know what causes it.
22:37.279 --> 22:38.522
[SPEAKER_00]: We know how to treat it.
22:38.705 --> 22:56.578
[SPEAKER_00]: And then, you know, for those people who like to use a mouth wrench, which is two out of three Americans, we now have an obligation because we know better to give them an alternative to the antiseptics, where you can use a mouth wrench, support the microbiome, improve nitric oxide production, and actually improve your systemic health.
22:56.778 --> 23:04.171
[SPEAKER_00]: So this is going to be a game changer because and you're not everybody's looking for nitric oxide products, but everybody, well, hopefully everybody brushes their teeth every day.
23:04.712 --> 23:07.256
[SPEAKER_00]: And we know that two out of three Americans use mouthwash every day.
23:08.018 --> 23:12.205
[SPEAKER_00]: So let's give them a healthy alternative that's going to improve their health rather than make them sick.
23:13.484 --> 23:15.206
[SPEAKER_02]: Absolutely fantastic.
23:15.226 --> 23:25.640
[SPEAKER_02]: Yeah, it's absolutely fantastic because you know, it's exactly what you said and you hope, but let's just say everyone brushes their teeth, right?
23:27.843 --> 23:31.027
[SPEAKER_02]: So and and two times a day, AM and PM.
23:31.588 --> 23:35.273
[SPEAKER_02]: So just by changing your toothpaste.
23:36.215 --> 23:58.240
[SPEAKER_02]: which you're doing anyway, you're brushing your teeth, you're doing so many other positive things for your body and your system on a molecular level on a cellular level, which is preventative, and that's the angle, but how come so many dentists
23:58.220 --> 24:03.167
[SPEAKER_02]: are still giving out samples of toothpaste with fluoride.
24:03.567 --> 24:07.392
[SPEAKER_02]: I mean, this, this is not even being talked about.
24:08.394 --> 24:09.335
[SPEAKER_03]: It's their habit.
24:09.355 --> 24:10.216
[SPEAKER_03]: It's what they know.
24:10.236 --> 24:11.077
[SPEAKER_03]: It's what they do.
24:11.177 --> 24:13.621
[SPEAKER_03]: It's the companies that provide them with the samples.
24:14.502 --> 24:15.764
[SPEAKER_00]: And it's still fine.
24:16.004 --> 24:18.748
[SPEAKER_00]: It's, it's, it's Heather train, but we're making headway.
24:19.248 --> 24:22.793
[SPEAKER_00]: You know, I spoke in Chicago before the American Civil Association,
24:22.773 --> 24:43.431
[SPEAKER_00]: Last year maybe maybe a couple of years ago, but we're finally getting their attention because as you girls know the systemic health begins in the mouth And so we have to get rid of fluoride the risk benefit analysis on fluoride the jury's in there is no benefit and it's it's it's all risk and that's an easy quote You just eliminate your exposure to fluoride
24:44.778 --> 24:51.589
[SPEAKER_00]: But then, you know, we have to start understanding how to not just because like oral pathogens are bad, right?
24:51.609 --> 24:57.278
[SPEAKER_00]: We know there's translocation, a oral bacteria that can cause systemic inflammation and it caused plaque rupture and heart attack and it's true.
24:57.899 --> 25:05.571
[SPEAKER_00]: So the challenge in the dental community is how do you address the oral pathogens without throwing an atomic bomb in the mix and killing everything?
25:06.142 --> 25:16.838
[SPEAKER_00]: And so that's what we're coming in because what we're finding is that nitric oxide, pathogenes are selected or sensitive to nitric oxide, with a non-pathogenic commensals make nitric oxide.
25:17.759 --> 25:30.217
[SPEAKER_00]: So if you restore nitric oxide production or in the best examples the lawzons, we generate nitric oxide gas in the oral cavity, it's selectively kills the oral pathogens and it improves the diversity of the oral microbiome.
25:30.237 --> 25:33.482
[SPEAKER_00]: So just using what we're
25:33.462 --> 25:41.218
[SPEAKER_00]: You know, at the very minimum is going to dramatically transform your health because it's going to improve nitric oxide production.
25:41.238 --> 25:49.395
[SPEAKER_00]: It's going to recouple the enzyme and the lining of the blood vessels and it's going to restore the oral microbiome and improve the natural production of nitric oxide.
25:50.624 --> 26:10.782
[SPEAKER_02]: See, so even something like that, I take the laws and now I'm understanding even more so that by keeping the laws in my mouth and having it, you know, dissipate or dissolve in my mouth, that's adding another benefit to my entire system.
26:10.802 --> 26:14.986
[SPEAKER_00]: So that's how we designed that laws into like that because here's what I wanna do.
26:15.006 --> 26:18.589
[SPEAKER_00]: I never wanna give the body something that it's not used to see.
26:18.839 --> 26:26.701
[SPEAKER_00]: So we had to do a little bit of mathematics, but I understand how much nitric oxide gas is produced in a 24-hour period under optimal conditions.
26:27.303 --> 26:34.603
[SPEAKER_00]: Through dye and through the oral microbiome, through secretion of stomach acid, and through this enzyme nitric oxide synthase.
26:34.685 --> 26:42.698
[SPEAKER_00]: Then we had to do some calculations on how much of that is disturbed or missing in the American population, the global population.
26:43.399 --> 26:47.846
[SPEAKER_00]: And then to develop a dietary supplement, it's meant to supplement what's missing, right?
26:48.026 --> 26:53.976
[SPEAKER_00]: And so that's what we do in supplements, drug therapy is completely different, it's just average safety and efficacy.
26:53.956 --> 26:55.480
[SPEAKER_00]: So we want to create the delta.
26:55.981 --> 27:02.398
[SPEAKER_00]: But again, nitric oxide is a gas and we try to mimic the flux and rates of production that would normally occur.
27:03.020 --> 27:09.737
[SPEAKER_00]: So we had to design this only disintegrating tablet that releases a certain amount of nitric oxide over a certain period of time.
27:09.717 --> 27:20.595
[SPEAKER_00]: because you don't want to hit the system with a bolus of nitric oxide that would completely dilate all the blood vessels lead to a loss of blood pressure, profusion and then people get lightheaded, syncopy and pass out.
27:20.635 --> 27:22.899
[SPEAKER_00]: We have to slowly titrate this in.
27:22.939 --> 27:27.207
[SPEAKER_00]: So this laws and is designed to dissolve over five to six, seven minutes.
27:28.048 --> 27:32.215
[SPEAKER_00]: And so you just move it in your mouth and it's slowly dissolved with its releasing nitric oxide.
27:32.195 --> 27:34.418
[SPEAKER_00]: But it's changing the environment in the oral cavity.
27:34.438 --> 27:35.299
[SPEAKER_00]: It's vasoactive.
27:35.319 --> 27:38.263
[SPEAKER_00]: We see dilation of your crotties within 10 or 12 seconds.
27:38.924 --> 27:42.810
[SPEAKER_00]: We see a 20% improvement into the little nitric oxide production within 20 minutes.
27:43.330 --> 27:48.478
[SPEAKER_00]: You know, sexual function improves blood pressure, normalizes, increased number of stem cells in circulation.
27:48.518 --> 27:55.367
[SPEAKER_00]: Everything that nitric oxide is known to do, the law's inch does itself because it's producing nitric oxide.
27:56.073 --> 28:02.500
[SPEAKER_03]: You know, what you're doing sounds like in a different way because you're using actual ingredients.
28:03.101 --> 28:08.347
[SPEAKER_03]: But it sounds like this is very similar to what we do and it's information medicine.
28:08.827 --> 28:15.475
[SPEAKER_03]: You're feeling the body by restoring cellular signals or cellular communication without the chemicals.
28:16.476 --> 28:21.642
[SPEAKER_03]: So why are all the signals getting disrupted to begin with?
28:22.178 --> 28:29.345
[SPEAKER_00]: like there's so many disruptors in the environment in which we live, whether it's 5G or electromagnetic frequencies.
28:29.365 --> 28:35.772
[SPEAKER_00]: And you know, one of molecular, kind of a atomic scale, we have to, you know, there's all this energy flow.
28:35.792 --> 28:38.455
[SPEAKER_00]: There's electron flow and, you know, there's conductance.
28:38.515 --> 28:42.499
[SPEAKER_00]: You know, and, you know, we diagnose death by loss of electrical activity.
28:42.880 --> 28:47.224
[SPEAKER_00]: But, you know, humans aren't like a light switch where you turn it on and off or we're batteries.
28:47.204 --> 28:50.150
[SPEAKER_00]: And so, you know, in your fly side, if you're better, you get slow, you're like this.
28:50.771 --> 28:52.796
[SPEAKER_00]: And our light dims, right?
28:53.277 --> 28:54.800
[SPEAKER_00]: And our body always talks to us.
28:54.880 --> 28:59.871
[SPEAKER_00]: And that dimming of the light and the loss of electrical activity shows up as erectile dysfunction.
28:59.891 --> 29:03.458
[SPEAKER_00]: High blood pressure, autoimmune disease, illness, or disease.
29:03.438 --> 29:18.198
[SPEAKER_00]: And so we've got to get back to the fundamentals and restore these these circuits, the information, whether it's, you know, the nervous system and nerve conductance or whether it's the cardiovascular system delivering oxygen nutrients to every organ tissue and cell on the body.
29:18.599 --> 29:19.660
[SPEAKER_00]: I mean, that's where it all starts.
29:19.700 --> 29:24.687
[SPEAKER_00]: But as you say, we have to restore the flow of information and restore normal signaling.
29:24.667 --> 29:32.658
[SPEAKER_00]: in the signal transduction because since the outside environment can then change the expression of genes and proteins to adapt to that new environment.
29:33.079 --> 29:37.365
[SPEAKER_00]: But that's information that signal transduction that's lost in almost every disease.
29:37.385 --> 29:50.083
[SPEAKER_00]: So if we can restore that through through the code type technology or just improving nitric oxide and circulation and blood flow
29:50.654 --> 30:10.030
[SPEAKER_03]: Does it help people detox also like say you have sluggish blood and your lymphatic system isn't really draining because like you said you're living a sedentary life or you're not exercising enough for all these environmental toxins and pollutants stress poor diet all these factors.
30:10.010 --> 30:16.762
[SPEAKER_00]: For sure, the purpose of the cardiovascular system is to deliver and oxygen nutrients to cells and then take out the waste products.
30:17.443 --> 30:22.792
[SPEAKER_00]: If you compromise and you have poor blood flow, poor circulation, poor vascular health, then neither that's happening.
30:22.812 --> 30:30.125
[SPEAKER_00]: You're not getting nutrients to cells and then they're building this metabolic waste products and then these cells become toxic and dysfunctional.
30:30.145 --> 30:33.891
[SPEAKER_00]: So we got to get the good stuff in, we got to take out the bad stuff.
30:33.871 --> 30:45.207
[SPEAKER_00]: And that occurs both in the cardiovascular system, the lymphatic system, the lymphatics, have their own endothelial cells that produce nitric oxide that kind of control lymphatic flow and, you know, they're removal of toxins.
30:45.908 --> 30:58.967
[SPEAKER_00]: But yeah, it's all we call foundational, you know, but there are also other things you have to incorporate in this, you know, nitric oxide is not a silver bullet, it's foundational, but it's not going to fix everything that's wrong with everyone, you still have to address other problems.
30:59.048 --> 31:13.729
[SPEAKER_03]: But do you find in your work that like we find in hours when you decrease stress in the body seemingly unrelated things resolve so when you restore this nitric oxide in the body do you find that seemingly unrelated issues resolve.
31:15.492 --> 31:17.715
[SPEAKER_00]: Yeah, we did there's a lot of things together.
31:18.151 --> 31:31.789
[SPEAKER_00]: Look, the body is an intricate system of different networks and organ systems, but what we find is that if you restore blood flow and improve oxygen delivery and mobilize stem cells and activate mitochondria, every cell in the body works.
31:32.670 --> 31:46.808
[SPEAKER_00]: But again, if you're not good at dealing with stress and you've got you know, sympathetic overdrive and dysautonomium, you still have to correct that, you know, because even though we're increasing blood flow, if you're not good at dealing with stress,
31:47.075 --> 32:03.058
[SPEAKER_00]: Well, what I've learned is, and this took me some time because there's, you know, we live in a stressful environment, a lot of stressful things happen to us, but, you know, I've just made it kind of a practice that I don't worry about anything I can't control, I can't control it, I don't worry about.
32:03.393 --> 32:11.606
[SPEAKER_00]: And when you start to think about it, how much can we actually control zero really little so you know what I don't worry about anything I wake up every morning with gratitude with the servant's hard.
32:11.626 --> 32:19.379
[SPEAKER_00]: I want to go out and do the best I can control what I can help and I don't stress there's cannot stress me and I've made it a practice.
32:20.882 --> 32:23.305
[SPEAKER_02]: That is the best advice.
32:23.967 --> 32:26.110
[SPEAKER_02]: Yeah, that you could give someone.
32:26.562 --> 32:51.169
[SPEAKER_02]: because when you're able to really remove yourself from that and realize you can't control anything, except for what you do and you have that power of knowing that, living that, breathing that, it changes your entire perspective on the way that you handle everything, everything.
32:52.043 --> 32:52.785
[SPEAKER_02]: takes a lot.
32:53.045 --> 32:55.209
[SPEAKER_02]: I mean, it takes a lot to be able to do that.
32:55.851 --> 32:57.915
[SPEAKER_02]: But it's practice.
32:58.015 --> 32:59.198
[SPEAKER_02]: It's mindfulness.
32:59.538 --> 33:02.504
[SPEAKER_02]: And that's what Lisa and I talk about all the time.
33:02.544 --> 33:04.088
[SPEAKER_02]: It's mindfulness.
33:04.749 --> 33:11.723
[SPEAKER_02]: Back to the original question of consciousness and how it's all interconnected.
33:11.703 --> 33:12.584
[SPEAKER_00]: For sure.
33:13.265 --> 33:38.571
[SPEAKER_00]: Yeah, and I like that's why I like hanging out with with with with you guys and like minded people who Who see the importance of intention and consciousness and manifesting things whether it's in our personal life from our professional life and you know We got a red red ourselves of people who are energy Steelers and who want to steal your dreams and tell you what you're doing It's impossible or stupid and it's never gonna work and you know, I just don't a lot of
33:38.551 --> 33:42.616
[SPEAKER_00]: You know, again, this has been a process of a journey that you have to eliminate those people.
33:42.716 --> 33:46.741
[SPEAKER_00]: And you know, as we all know, you, you are who you're surround yourself with.
33:46.761 --> 33:47.001
[SPEAKER_00]: Right.
33:47.342 --> 33:54.510
[SPEAKER_00]: Your stuff is so, you know, I'm very picky about who I allow into my space and, you know, my inner circle.
33:54.830 --> 34:02.740
[SPEAKER_00]: Because I've, you know, I've been around toxic people and, you know, get in business with a lot of toxic people that, you know, try to destroy my life.
34:02.760 --> 34:05.203
[SPEAKER_00]: And if I would have let them, they would have been successful.
34:05.263 --> 34:07.005
[SPEAKER_00]: But that's not happening anymore.
34:07.323 --> 34:08.486
[SPEAKER_02]: Yeah, I love that.
34:08.506 --> 34:12.336
[SPEAKER_02]: Well, thank you for allowing us to be in part of your inner circle.
34:12.356 --> 34:14.743
[SPEAKER_02]: We love that part of the heart inner circle.
34:14.803 --> 34:23.847
[SPEAKER_02]: And we do, we just cannot say enough about what you and Susan are doing.
34:23.827 --> 34:40.148
[SPEAKER_02]: Um, it is so important for people to really understand and I say this with with true integrity and a full heart really, there are so many products that are out there and it doesn't matter what.
34:40.128 --> 34:42.871
[SPEAKER_02]: supplement, or you can have anything out there.
34:42.911 --> 34:52.462
[SPEAKER_02]: There are great quality companies, and then there are just companies that are just trying to make a quick buck, and they're not doing it the right way.
34:53.063 --> 35:09.662
[SPEAKER_02]: And Lisa and I can really say you are doing it the right way, the research, the technology that has gone into this, even for someone to understand that there are so many other nitric
35:10.098 --> 35:13.054
[SPEAKER_02]: but if it's not being released.
35:13.507 --> 35:19.172
[SPEAKER_02]: in the proper way, it could literally be so damaging to an individual.
35:19.212 --> 35:40.712
[SPEAKER_02]: So just for our viewers and for the audience just really before, you know, not just with Dr. Nathan's N101 products, but with everything that you are looking to use, it is so important to know and understand what you are actually putting on and in your body.
35:40.692 --> 35:57.799
[SPEAKER_02]: because that one thing that you think is doing good for you because, you know, an influencer set it or because it's less expensive than something else can be doing the most harm and just thank you.
35:58.140 --> 36:07.915
[SPEAKER_00]: Thank you for saying because there's so many consumers are confused because I
36:07.895 --> 36:12.438
[SPEAKER_00]: And that's one of the biggest fraudulent, deceptive marketing campaigns out there.
36:12.458 --> 36:13.785
[SPEAKER_00]: Beats are not nitric oxide.
36:13.805 --> 36:16.096
[SPEAKER_00]: You don't get nitric oxide from the eats.
36:16.157 --> 36:16.639
[SPEAKER_00]: And so,
36:16.940 --> 36:18.743
[SPEAKER_00]: You know, there's, you met a good point.
36:18.763 --> 36:20.886
[SPEAKER_00]: There are a lot of good companies out there still in a lot of good products.
36:20.987 --> 36:24.593
[SPEAKER_00]: But this isn't a vitamin C or vitamin D. You could throw in a capsule.
36:24.613 --> 36:25.975
[SPEAKER_00]: This is nitric oxide gas.
36:26.636 --> 36:30.022
[SPEAKER_00]: And I just simply asked if you trust us as your nitric oxide product.
36:30.042 --> 36:34.970
[SPEAKER_00]: Because we spent the time in the lab doing the research, understanding the biochemistry and physiology.
36:35.651 --> 36:41.901
[SPEAKER_00]: And all these other companies out there, they just want your money, they're trying to sell you a bill of goods, and they don't understand the science.
36:42.151 --> 36:49.020
[SPEAKER_00]: and the people, the companies who spend the most on advertising, obviously have the poorest sites to keep that in mind.
36:49.040 --> 36:49.660
[SPEAKER_02]: Very true.
36:50.121 --> 36:56.689
[SPEAKER_03]: I will say Wendy, yeah, I do have one more question because I know our time is coming to the end.
36:56.909 --> 37:03.418
[SPEAKER_03]: And you did discuss that the mouthwash is coming out soon, but give us the inside scoop.
37:03.458 --> 37:04.819
[SPEAKER_03]: What else is in the pipeline?
37:05.040 --> 37:07.703
[SPEAKER_03]: What are you moving towards in the future?
37:07.683 --> 37:10.828
[SPEAKER_00]: Like we have grant expectations and we're on a mission.
37:11.148 --> 37:15.134
[SPEAKER_00]: So we're going to, you know, we've got a supplement line and additional line.
37:15.855 --> 37:19.360
[SPEAKER_00]: We've got the skin care line with clean skin care line of products.
37:19.400 --> 37:21.724
[SPEAKER_00]: The N101 we're building out an oral line of products.
37:21.764 --> 37:24.688
[SPEAKER_00]: The toothpaste and the mouth rinse called breath of life.
37:25.329 --> 37:29.235
[SPEAKER_00]: You know, we're moving into animals for pets, you know, because.
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[SPEAKER_00]: You know, they're mammals as well and need nitric oxide, and so, you know, on several third-brad race horses, we're improving performance in our third-brad horses and, you know, preventing pulmonary beliefs, but so we'll move into veterinary space and then, you know, we're developing our drug therapy, where, you know, my goal was to develop dietary supplements, I could say that my goal was to understand the mechanism of disease to the extent we could develop rational drug therapy.
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[SPEAKER_00]: So we're moving our drug therapy through clinical trials.
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[SPEAKER_00]: I've got a drug for heart disease.
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[SPEAKER_00]: We mentioned the introduction.
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[SPEAKER_00]: We're making a drug for Alzheimer's, which, you know, I'm convinced we'll completely eradicate Alzheimer's and dementia.
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[SPEAKER_00]: And then we're making a topical drug for diabetic ulcers and non-healing wounds.
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[SPEAKER_00]: But those three are the beginning.
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[SPEAKER_00]: But, you know, we'll continue to develop drug therapy for things like heart failure.
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[SPEAKER_00]: You know, nitric oxide is extremely important for pulmonary infections.
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[SPEAKER_00]: And for things like migraines and acne.
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[SPEAKER_00]: What we're finding is there's not a single indication or nitric oxide at the right dose at the right time in the right patient, would not be beneficial.
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[SPEAKER_00]: So my job is to create the technology that addresses specific needs for specific indications.
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[SPEAKER_00]: It's not only safe, but effective without chemicals, synthetic compounds, as basically restorative physiology, given the body back what it needs so the body can heal.
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[SPEAKER_03]: love it and it's very synergistic with with what we do as well and a lot of the things that you mentioned sounds like very similar things that we have in our pipeline.
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[SPEAKER_02]: So I want to
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[SPEAKER_00]: Well, first, I will shamelessly plug my latest book called the Secret of Nitrocoxide, bring the science to life.
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[SPEAKER_00]: This tells the story of Nitrocoxide, but also my personal journey of discovering the kind of my early, early years and then through academia and then what led to the development of our product technology.
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[SPEAKER_00]: But yeah, it's a great thing.
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[SPEAKER_00]: Amazon Barnes and Noble Nathan's book.com.
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[SPEAKER_00]: There's a link, I encourage people to follow and subscribe to my YouTube channel, Dr. Nathan S. Brian, nitric oxide, my Instagram, Dr. Nathan S. Brian, same on LinkedIn, X, Dr. Nitric, and for those interested in our products, it's in101.com.
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[SPEAKER_00]: That's the letter
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[SPEAKER_03]: perfect.
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[SPEAKER_03]: Thank you so much for being with us today.
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[SPEAKER_03]: We really enjoyed this code conscious conversation.
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[SPEAKER_00]: We need to thank so much and look forward to seeing you soon.
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[SPEAKER_01]: Unconventionly dare to explore Breaking barriers open indoors With every step they lie the way I need
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[SPEAKER_01]: One mission, lighting away, transforming the future with love every day With science and spirit, their journey unfolds Restoring balance as the future unfolds
