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Hi, my name is Chris Burris.
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I'm a longevity expert and the chief scientist at a lab focused on a longevity molecule.
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My primary focus is to help people live longer and better lives with science.
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Make sure to subscribe and share so you and your friends can live longer and better.
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Well, actually, so you and your friends can live beyond the norms.
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Hi, and welcome to the next episode of the Live Beyond the Norms Health and Longevity Podcast.
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You've been told aging is inevitable, but what if that is just not true?
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What if turning 60, 80, or even 100 did not have to mean weakness, disease, and decline?
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Our next guest, Dr. Jeffrey Gladden, is here to help us reframe our perspective on aging with his 40 plus years of experience as a medical doctor and longevity expert.
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A little bit about Dr. Gladden.
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Dr. Gladden is a pioneering longevity physician, interventional cardiologist, and founder of Gladden Longevity and Advanced Performance Center in Dallas, Texas.
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Go Texas, because I'm also in Texas.
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He is the author of the book, 100 is the New 30, How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime.
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He is also the host of the popular Gladden Longevity podcast.
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His mission is to give us the tools so we can live young for a lifetime.
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Hopefully, we can help him on that mission in this interview today.
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Dr. Gladden, thank you so much for joining us today.
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Yeah, Chris, great to be here.
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Thank you.
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So before we jump into your areas of expertise, I want to go further back.
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I want to go much further back.
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What was it like growing up little Jeffrey, or maybe it was Jeff?
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Where did you grow up?
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And what were your parents like?
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If there was some event or someone you could pinpoint as the reason you would ultimately become a longevity pioneer and champion for human optimization, what or who would that be?
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Yeah, that's a good question.
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Well, I was born in Michigan and moved to Philadelphia when I was seven or the suburbs of Philadelphia and kind of grew up there.
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I think, you know, my father was athletic.
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He played golf and fished and did some jogging and stuff like that.
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My mother also actually was a pretty good golfer, but her back always gave her a bit of trouble.
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Yeah.
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But they were both high-energy people, right?
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And they would Zoom around doing all kinds of stuff and traveled and did everything.
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I was very close to my mother's parents, and...
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My grandfather, maternal grandfather and I were very close.
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And my grandmother, she started to age, started this mantra of, Jeff, it's hell to get old.
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You don't ever want to get old.
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So I started hearing that, right?
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Even as a teenager, late teens, early 20s.
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Then later, my mom picked up that same mantra.
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Jeff, it's hell to get old.
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You don't want to get old.
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So, yeah.
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You know, I'd heard that.
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I also was athletic, played some soccer and basketball, a little bit of soccer in college, things like that.
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And, you know, I think like many of us, we leverage our health for the sake of building our businesses or that sort of thing.
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So that's what happened to me.
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Right.
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I.
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I basically went to medical school, did internal medicine, then did the International Cardiology Fellowship.
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So a decade after all of that training, I started my practice here down in Texas.
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Well, hold on a second.
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I want to kind of dwell in this space a little bit.
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One, played soccer.
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Awesome.
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Did you enjoy the World Cup?
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Were you catching any games?
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Yeah, I did.
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I caught most of them actually on YouTube so I could see the condensed version at 2x, right?
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That's how I watch soccer.
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It's too slow otherwise.
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Yes, what an amazing cup.
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My wife and I have been to Russia and then Qatar and then this one and basically the goal is to never miss one.
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Cool.
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That's awesome.
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And then the phrase, hell to get old, you don't ever want to get old.
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I always kind of describe it as, well, better than the alternative, right?
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Because the alternative of not getting old is not being around.
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I don't know.
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Go ahead.
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I think that's debatable.
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Well, yes, at some level of infirmment, yes, that's absolutely debatable.
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Anybody in your family in medicine?
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Was this like you were always destined?
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No, my mom wanted me to be a doctor.
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I had an older sister that had an anoxic birth and had brain damage from that.
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She was three and a half years older than I was.
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And so there was always sort of a medical, a special needs person in my family, which, you know, thinking about her brain and her brain injury and things like that, I think was also a stimulus for going into medicine.
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But, you know.
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You know, I've also kind of been on a spiritual path my entire life, ever since I was three years old, you know, walking down the street, coming back from a pond where I was catching frogs, debating the existence of God, and someday deciding I wanted to become wise.
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Wow.
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So at three, after catching frogs, that's a great three-year-old thing.
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You are also debating or thinking about the future of being wise.
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That's very cool.
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So do you continue to read lots of diverse books just outside of medicine as well?
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Yeah, so I did that, and my parents were, you know, in a Protestant Christian tradition, so they put me in Christian schools through kindergarten through 12, and I went to Wheaton College, and I actually didn't get accepted into medical school right away.
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I was the first person in my family to ever go to four years of college, and so I never studied for the MCAT.
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I just sat down and took it and, you know, stuff like that.
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I majored chemistry instead of biology, so I wasn't very smart about it, but, you know,
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Once I got into medical school at Temple, then I really excelled there.
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At Wheaton, you studied chemistry.
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Was the intent already to go for medical school, and you just weren't necessarily preparing properly?
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It was an interesting thing.
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I was really on the fence between...
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you know, doing something in the spiritual space or going to medical school.
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And so I majored in chemistry because I knew it would be a lot harder than biology.
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And I thought, well, if I'm going to get washed out, let me get washed out early.
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But I kept being good enough to stay in chemistry, but not good enough to have a 4.0, right?
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And this was...
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Back when I was applying, it was the highest applicant pool that they'd ever had in the U.S., right?
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So a lot of people competing for spots.
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And so, you know, it kind of worked out that way.
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But in the end, I was grateful for it because it enabled me to actually go to seminary for a couple of quarters when I didn't get in.
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Yeah.
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and figure out that I really didn't want to go down that path.
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I could always think about, you know, theology, philosophy, God, spirituality.
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I didn't have to have a degree to do that, but if I was going to do medicine, I needed a degree.
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So I went back and Temple had really liked me in the interview.
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but wanted me to boost my grades, so I did that.
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Took some more undergrad biology courses, worked in a research lab for a year, and then they say if you do that, you know, we'll take your early acceptance.
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So that's kind of how it worked.
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So, yeah.
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Very cool.
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So now you're off and running in medicine, getting your medical degree.
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You often have these kind of
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times to change your path into kind of different specialties.
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Did you consider a bunch of them?
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I think you ended up interventional cardiology.
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Yeah, I did.
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Yeah.
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And that's another interesting story.
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So I went into internal medicine because I liked the integrative –
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elements of internal medicine.
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It's interesting, when I was in medical school, a friend of mine and I would sometimes talk about the fact, wouldn't it be interesting if we could take all this technology, all these labs and everything, and work on optimizing a human being as opposed to just trying to treat them and pull them out of the fire, right?
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And that was the earliest...
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My earliest thoughts about, you know, optimizing human life really happened in medical school.
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But, of course, in your training, there's no focus on that.
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You're basically just training on taking care of sick people, helping sick people, which is admirable in and of itself.
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But I think that concept never really left me.
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I've been an optimizer my whole life, you know, whether it was my bicycle or...
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a dirt bike or the snowboard settings or a mountain bike or, you know, it's always like, how do you dial this in, right?
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So that the equipment is like, you know, working perfectly with you and you can kind of get into that flow state with it.
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So, I brought that and I did it when I was an interventional cardiologist.
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I would always be optimizing stuff too.
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So that mindset is there.
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But back to your question about how did I choose cardiology?
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Well, that was interesting because when I finished internal medicine, I knew I didn't want to be an internist.
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I didn't want to have those conversations.
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I think life is really about having the conversations you want to have, right?
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And so I went through all the different specialties, you know, pulmonary, GI, neurology, you know, dermatology, rheumatology, nephrology, you know, and I was like, no, no, no.
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Cardiology, well...
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I guess.
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So I applied for cardiology.
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Sounds like it was your passion when you put it that way.
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That's right.
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I guess, right?
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That's really what it was.
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I'm being very, very candid with you here.
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And then I got accepted into an interventional program at the University of Colorado.
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And so I went out there and I really kind of fell in love with it.
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You know, it had a really great blend of...
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intellectual problem solving, and also technical manual interventional skills, right?
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Placing, you know, balloons and ultimately stents and intravascular ultrasound and, you know, lots of different things.
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So it had a procedural basis to it.
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It also had lots of different testing, not only blood testing, but also biometric testing like stress tests and nuclear stress tests and things like that.
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So I ended up being board certified in internal medicine, cardiology, interventional cardiology, nuclear cardiology, right?
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So I ended up with all those certifications because, number one, I'm eternally curious, and number two, I like optimizing stuff.
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And number three, I really became very passionate about how do we
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take this field, which at that point was really exploding with technology and insight.
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You know, the first stents were placed just a few years before I got into it and things like that, right?
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The first balloon angioplasty rather were placed.
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So, and the stents didn't exist when I started.
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So, you know, all of that stuff's coming online.
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I was one of the first people to ever do intracorneal ultrasound in Texas.
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And
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And then I was training anesthesiologists on how to do transesophageal echoes.
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Instead of putting a probe on your chest to look at the heart, we'd go into the esophagus and look at it.
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So I learned how to do that.
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And, you know, then I started my own heart group.
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I started building cath labs.
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I, you know, co-founded a heart hospital, got involved with medical device companies.
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So, you know, it's kind of like eternal curiosity is really what it is.
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And how do we do it better?
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How do we have a better...
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understanding, a deeper understanding.
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And one of the things I learned as an interventionalist was that if I had a deeper understanding, that I could always get a better outcome for the individual.
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So armed with that, we actually started cath labs and would do interventional cases in hospitals with no surgical backup because we were so confident in our ability to select people who would
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be able to do that safely.
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And the technologies we applied in addition to what most people were doing allowed us to see and understand more deeply.
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We were doing genetics when nobody was doing genetics.
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We were doing intracorneal ultrasound to see what was inside the artery in the plaque before.
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Nobody was doing that or very few people.
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But we could get amazing results for people.
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And we're like, this is really cool.
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No, that's fascinating.
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So one question is, as you're kind of going through these, you know, potential specialties, your kind of, we'll say, passion for spirituality, did you ever think about kind of neurology and how that might tie into spirituality or that skipped in you?
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You know, you were like, oh, well, why not?
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I do now, but I didn't then.
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Interesting.
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Yeah.
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It's funny hindsight.
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So when you're testing from the inside, looking at the heart, are you looking at plaques and things?
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What is it that you're able to see better?
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Well, with transesophageal echo, we can look at the big structures of the heart, the chambers, the valves, all of that in much more detail than we can when we look through the chest.
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Because the heart sits right against the esophagus.
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And so when you're in the esophagus, you're looking straight into the heart.
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When you come through the chest wall, you've got to bypass the lungs, right, which air blocks ultrasound.
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So you've got to navigate that to try to get the images.
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So you actually get clearer, more detailed pictures, of course, when you come from the esophagus.
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You have to sedate the person like an upper endoscopy.
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But once you learn to do that, and it only took about 10 minutes to do the study because you could capture what you needed to quite quickly, right?
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Yeah, so anyway, that's one way to look at it from the inside out.
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The other was if you do a coronary angiogram, you know, you put a catheter into an artery and squirt some dye down there.
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But now you have to understand you're looking at a two-dimensional representation of a three-dimensional structure.
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So understanding that, what we would do is thread a little guide wire down the artery.
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And then we would put an ultrasound catheter over the wire so that now we're inside the artery looking at it 360 degrees from the inside out.
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And from that, we could actually see that the angiogram was misrepresenting what was happening a great deal of the time.
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Areas that looked normal were not normal.
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Areas that looked somewhat narrowed weren't actually very narrowed at all.
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Areas that didn't look that narrowed were actually very tight.
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And so I'm like, oh, my gosh, this is a revelation.
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And so we would go in and use the ultrasound and then map out where the stening needed to occur, if that's what we were going to do.
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And we would do that, and then we would inflate the stent, go back and look at it again to make sure that it was fully deployed, that the artery was at its natural size.
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And what we discovered was that many cardiologists were being fooled by the angiograms.
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They'd put stents in, but they would under-dilate them.
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And so then people would still be left with a restriction.
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So we had the technology, if you will, to actually map things and then get people the optimal results.
218
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And we used to high five at the end of cases.
219
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after we do these cases saying, you know, nobody in the world could have done this case better.
220
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And it was literally true.
221
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Nobody in the world could have done that case better with what we had to work with at the time.
222
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Because we were so meticulous about the deconstruction of what's really going on and then applying the therapies in the proper way.
223
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And that mindset is what I've carried into the longevity space.
224
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Yeah.
225
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It must have been incredibly exciting just to have stents as an option, right?
226
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And then your curiosity.
227
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So you're talking about, oh, technology.
228
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It's not just technology.
229
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It's also the curiosity of, like, is this really happening?
230
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That's right.
231
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I've worked in kind of oil and gas field as a mechanical engineer.
232
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And you get these pumps and they have this, well, pressure gauges and they have a calibration curve.
233
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And I confirm the calibration curve.
234
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is not accurate, right?
235
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You know, so a lot of engineers are just taking this calibration curve.
236
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They work.
237
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So you're like rolling up your, your, your sleeves and, and getting well, well in there.
238
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That's, that's pretty fascinating.
239
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Um, all right.
240
00:16:09.669 --> 00:16:13.592
So then you have this transition in the introduction to your book.
241
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You mentioned that we only get answers to the questions we ask in terms of longevity.
242
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What is the most important question we should be asking?
243
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Yeah.
244
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Yeah, I think, you know, that realization came out of my own story, as you know, from the book where I got sick and I was told, you're just getting older, why don't you take any antidepressant?
245
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And two and a half years later, after the whole going down the functional internal, you know, integrative medicine, age management medicine rabbit hole, I figured I had figured everything out.
246
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Of course, I had the help of other people.
247
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It was then that it dawned on me, you know, because I'm asking the question, geez, how do I fix this as opposed to how do I just treat it?
248
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And then when I started to feel really great again, I started to ask a question, geez, I wonder how good I can be.
249
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How good can I be?
250
00:17:00.445 --> 00:17:01.065
How fit?
251
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How strong?
252
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How mentally sharp?
253
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How many years and decades can we carry this forward?
254
00:17:05.648 --> 00:17:11.031
Because it was, I went from not being able to keep up with my kids to my kids couldn't keep up with me again, right?
255
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I mean, there was a lot in there.
256
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subclinical hypothyroidism, not being able to get out of bed to be bouncing out of bed again, you know, putting on weight to losing 20 pounds of fat and putting on 10 pounds of muscle, right?
257
00:17:22.800 --> 00:17:37.833
Getting anxious and depressed and not getting depressed at all or knowing exactly what to do if I do start to feel depressed, you know, all based on genetic, all based on thorough deconstruction and reconstruction of what my biology needs based on my genetics and my biochemistry.
258
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And so,
259
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Um, I'm like, wow, this is actually healthcare.
260
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I've been practicing sick care.
261
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I can't do it anymore.
262
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I don't want to have those conversations.
263
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I'm going to ask different questions.
264
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And the first one was, geez, I wonder how good we can be.
265
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Right.
266
00:17:51.773 --> 00:17:54.036
So now we're powered by five.
267
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You say that's healthcare, and that ties back to the conversations that you were having in medical school with your buddy.
268
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That's right.
269
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About, like, could we optimize, right?
270
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That's right.
271
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And so this is always on your mind.
272
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I don't know the kind of timing of functional medicine.
273
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Was it kind of always available but not on your radar, or did it come available and also on your radar at some point?
274
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It wasn't always available.
275
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It sort of started to come into vogue in the 90s, I would say.
276
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And, of course, I was busy doing cardiology.
277
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And one of the problems that physicians have is that we're all brainwashed when we're in medical school.
278
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We all get brainwashed because we go to good schools.
279
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You know, people are smart.
280
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We're learning interesting things.
281
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We're being taught by the best in the world.
282
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And then we go into training and everything else, and it's reinforced there.
283
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And you come out feeling like you've got all the answers that actually matter.
284
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And it wasn't until I got sick myself and realized that there was an entire universe of answers out there that I didn't know about that.
285
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that I then realized, oh, those guys over there that are doing quote-unquote functional medicine, they've got some interesting insights over there, right?
286
00:19:07.636 --> 00:19:09.517
Or the naturopaths or whomever else.
287
00:19:10.157 --> 00:19:15.220
It's like, and again, being eternally curious, I'm like, geez, I want to go see what they're doing, right?
288
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Now, most of my colleagues aren't like that.
289
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It's like, no, I wouldn't go over there.
290
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We have it all figured out.
291
00:19:20.703 --> 00:19:21.723
But I'm like, no, you don't.
292
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You couldn't fix me.
293
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I couldn't fix myself.
294
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I'm going to go see what's over there.
295
00:19:26.326 --> 00:19:27.987
So that's kind of how that went, yeah.
296
00:19:28.647 --> 00:19:30.128
And that may tie in here, right?
297
00:19:30.428 --> 00:19:37.693
So your book's title has the byline, how playing the symphony of longevity will enable us to live younger for a lifetime.
298
00:19:37.713 --> 00:19:42.856
In a symphony, timing, coordination, balance, all that matters more than any one instrument.
299
00:19:43.156 --> 00:19:52.242
How do you see that as a parallel for somebody's longevity journey or maybe somebody who's visiting you for a healthier health span for more longevity?
300
00:19:52.842 --> 00:19:53.083
Right.
301
00:19:53.223 --> 00:19:54.163
That's a great question.
302
00:19:54.704 --> 00:20:14.740
You know, what I've come to understand is that, and this will take a minute to explain, but, you know, medicine is really based on trying to fix disease and therefore, by default, helping people regain their quote unquote health, which they call wellness, right?
303
00:20:15.600 --> 00:20:19.844
So the positive side of sick care is wellness, right?
304
00:20:19.864 --> 00:20:20.084
Right.
305
00:20:21.398 --> 00:20:26.762
And I realized that that's a completely different question than how good can we be.
306
00:20:28.003 --> 00:20:37.111
And so in how good can we be, as I leaned into it, and there was a lot of random data coming around longevity back then.
307
00:20:37.131 --> 00:20:40.333
I left in 2012, so I've been doing this since 2012.
308
00:20:41.194 --> 00:20:43.996
It finally dawned on me how to integrate all this information.
309
00:20:45.397 --> 00:20:47.639
And so I developed a system.
310
00:20:48.278 --> 00:20:50.643
that consists of five circles.
311
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The first circle is the life energy circle, and it's really the one that binds all the other ones together.
312
00:20:59.287 --> 00:21:08.613
And then inside that circle is a Venn diagram of longevity, which is, you know, everybody and their brother now has a longevity clinic, right?
313
00:21:09.293 --> 00:21:16.518
It doesn't, it could be the spa, it could be the gym, it could be, you know, a doctor, it could be, you know, another practitioner of some variety.
314
00:21:18.339 --> 00:21:23.022
But the point is that most of these longevity clinics are focusing on health.
315
00:21:24.220 --> 00:21:29.442
And the comment that they make is, well, if you're healthier, you're going to live longer.
316
00:21:29.742 --> 00:21:30.422
Well, that's fine.
317
00:21:31.202 --> 00:21:31.682
It's true.
318
00:21:32.082 --> 00:21:33.983
But it's not really longevity medicine.
319
00:21:34.723 --> 00:21:40.945
Because longevity medicine is focused on the actual underlying biological drivers of aging.
320
00:21:41.815 --> 00:21:42.015
right?
321
00:21:42.495 --> 00:21:45.016
And that's a different set of things.
322
00:21:45.036 --> 00:21:46.417
They're called the hallmarks of aging.
323
00:21:46.437 --> 00:21:47.157
There are 12 of them.
324
00:21:47.737 --> 00:21:59.541
And it has to do with shortening telomeres and DNA repair mechanisms that don't work well and senescent cell accumulation and loss of stem cell function and immune cell decline and mitochondrial dysfunction.
325
00:21:59.601 --> 00:22:02.382
All these things that are kind of basic to many things, right?
326
00:22:02.442 --> 00:22:04.963
So, what I realized was that
327
00:22:06.328 --> 00:22:08.329
People are focusing on optimizing health.
328
00:22:08.730 --> 00:22:09.350
That's wonderful.
329
00:22:09.370 --> 00:22:16.535
But nobody's really going right at what's driving the current in the river that's taking us over the falls, which is the hallmarks of aging.
330
00:22:16.595 --> 00:22:17.896
So that's the longevity circle.
331
00:22:17.936 --> 00:22:18.796
We focus on that.
332
00:22:19.376 --> 00:22:21.918
Then, of course, there's health, every system and subsystem.
333
00:22:22.519 --> 00:22:27.422
And then for us, there's performance, because for us, the way we think about longevity is...
334
00:22:28.204 --> 00:22:36.582
is that longevity is actually the greatest opportunity humanity has ever had to upregulate or upgrade what the human experience is.
335
00:22:38.202 --> 00:22:44.583
And what I mean by that is that the target is not to live another 50 years so we can play golf and play with our great grandkids.
336
00:22:44.843 --> 00:22:45.944
I mean, we do want to do that.
337
00:22:45.984 --> 00:22:46.624
That's wonderful.
338
00:22:47.344 --> 00:23:00.106
The idea is when we're 100 and beyond and even before is to have a 30-year-old body or whatever age you choose, 18, 25, whatever you want, 42, pick your best age.
339
00:23:00.967 --> 00:23:02.687
So I picked 30.
340
00:23:03.067 --> 00:23:05.507
Have a 30-year-old body and develop a 300 or 3,000-year-old mind.
341
00:23:08.808 --> 00:23:09.048
Right.
342
00:23:09.769 --> 00:23:21.612
Because the world has never seen a group of people that are youthful with tremendous life experience that have developed this transcendent perspective.
343
00:23:21.652 --> 00:23:24.674
They've healed all the traumas that they've been living in reaction to.
344
00:23:25.334 --> 00:23:33.616
They've found ways to make themselves feel safe that's irrespective of anything external to themselves.
345
00:23:34.257 --> 00:23:37.538
They have come to the point of having unconditional love for themselves.
346
00:23:38.218 --> 00:23:42.999
They don't suffer with guilt and fear and anxiety and depression and things like this, right?
347
00:23:43.019 --> 00:23:44.160
They have great relationships.
348
00:23:44.180 --> 00:23:44.900
They have purpose.
349
00:23:44.920 --> 00:23:45.560
They have meaning.
350
00:23:46.420 --> 00:23:47.581
They have great wisdom.
351
00:23:48.061 --> 00:23:49.961
And they feel spiritually connected, right?
352
00:23:49.981 --> 00:23:54.863
Because every study ever done shows the people that are spiritually connected do better, live longer, recover faster.
353
00:23:55.687 --> 00:24:03.892
So the idea of having this 3,000-year-old mind and a 30-year-old body, it's like, wow, what would life be like then, right?
354
00:24:04.413 --> 00:24:08.595
It would be completely different than what we've come through, right?
355
00:24:08.615 --> 00:24:10.857
Because we spend a lot of time struggling, striving.
356
00:24:11.568 --> 00:24:16.153
trying to attain, trying to fend off, trying to defend, you know, who we think we are.
357
00:24:16.633 --> 00:24:25.262
And yet when you get to this point of more insight, you start to realize that we're going about it in kind of the wrong way, right?
358
00:24:25.843 --> 00:24:28.206
We get attached to outcomes, right?
359
00:24:28.226 --> 00:24:30.388
If the outcome doesn't occur, we stress about it.
360
00:24:32.007 --> 00:24:44.282
We don't realize that actually everything is going to work out for our benefit if we work from a flow state, right, where we're moving in sync with what's happening, not trying to overpower it all the time.
361
00:24:45.206 --> 00:24:49.248
And so I tell our clients that, you know, all of life really comes down to one thing.
362
00:24:50.409 --> 00:24:52.610
And everybody looks at me a little bit sideways, like, really?
363
00:24:52.750 --> 00:24:53.110
One thing?
364
00:24:53.290 --> 00:24:53.470
Yep.
365
00:24:53.891 --> 00:24:54.531
Just one thing.
366
00:24:55.231 --> 00:24:56.912
And it's optimizing our nervous system.
367
00:24:57.513 --> 00:25:09.319
How we think, what we believe, what we think is true, the stories we tell ourselves, what we're living in reaction to, what we think is possible, how we move, how we jump, how we run, how strong we are.
368
00:25:09.599 --> 00:25:11.280
All of it comes down to the nervous system.
369
00:25:12.347 --> 00:25:17.009
And so we spent a great deal of time in the life energy circle talking about the nervous system.
370
00:25:17.029 --> 00:25:19.850
It was just before I walked in here for the podcast.
371
00:25:19.930 --> 00:25:22.631
A client of ours just had a flare-up in a rheumatoid arthritis.
372
00:25:23.772 --> 00:25:27.613
So we went through the medical pieces, but we went to the life energy circle.
373
00:25:27.653 --> 00:25:30.494
It's like, oh, well, I've been on this book tour, and I've been doing this.
374
00:25:30.554 --> 00:25:33.636
I've been putting myself under a lot of physical stress, emotional stress.
375
00:25:33.716 --> 00:25:37.397
And, you know, I was committed to some outcomes and things like that.
376
00:25:37.417 --> 00:25:38.798
Well, let's deconstruct that.
377
00:25:39.198 --> 00:25:41.879
And all of a sudden, it's like, oh, yeah, I see it now.
378
00:25:43.140 --> 00:25:49.583
And so you can teach people how to actually go into flow states or into deep meditative states.
379
00:25:50.423 --> 00:25:53.585
And when they're able to do that, they calm the nervous system down.
380
00:25:53.985 --> 00:25:54.666
And guess what?
381
00:25:55.306 --> 00:25:59.228
When you calm the nervous system down, you slow down the aging process.
382
00:25:59.528 --> 00:26:08.393
Those 12 hallmarks of aging that drive the longevity circle all slow down when you are in more of a state of equilibrium, more of a Zen state.
383
00:26:09.073 --> 00:26:25.717
And even if you're going to get stem cells, exosomes, peptides, you know, all the things that, you know, we do a ton of all these things, people get a much better outcome if they're in a parasympathetic, calm, zen state than if they're stressed.
384
00:26:26.157 --> 00:26:27.997
The body can't heal when it's stressed.
385
00:26:28.678 --> 00:26:31.698
The body ages more rapidly when it's stressed, right?
386
00:26:31.758 --> 00:26:35.399
Blood sugar spike, cortisol spikes, you can't lose weight when you're stressed.
387
00:26:35.919 --> 00:26:38.780
That's why the life energy circle is the one that binds them all together.
388
00:26:39.500 --> 00:26:43.863
So performance is on there too, because we want to be fast, agile, strong, quick balance.
389
00:26:43.963 --> 00:26:45.864
I want to be able to do everything I want to do, right?
390
00:26:45.884 --> 00:26:46.685
I was born in 1954.
391
00:26:46.785 --> 00:26:52.328
I just got back from Vail this weekend on a little family get together.
392
00:26:52.489 --> 00:26:54.030
And my son and I were mountain biking.
393
00:26:54.590 --> 00:26:55.851
I live here at 600 feet.
394
00:26:57.352 --> 00:26:58.492
You know, we're mountain biking.
395
00:26:58.693 --> 00:27:01.654
We climbed 2,100 feet up to about 10,500.
396
00:27:01.694 --> 00:27:04.476
And then we're riding these trails up there, these downhill trails, right?
397
00:27:04.516 --> 00:27:07.318
We did a couple laps up there, did the rest of the mountain, right?
398
00:27:07.398 --> 00:27:08.939
went to a bike park in the afternoon.
399
00:27:09.619 --> 00:27:10.239
That's what I want.
400
00:27:10.259 --> 00:27:12.480
I want to be able to do anything I want to do, right?
401
00:27:13.940 --> 00:27:21.963
And that's a different concept of longevity than simply living a long time or living a long time so I can play more golf.
402
00:27:22.203 --> 00:27:26.205
I don't play golf, but if I did and I loved it, I would want to play more golf.
403
00:27:26.765 --> 00:27:35.034
But if you can have this really well-developed mind, right, and this youthful body, oh my gosh, it opens up just a complete new world of possibilities.
404
00:27:35.555 --> 00:27:39.879
And the fifth circle is the environments, right, architecting those to support the mission.
405
00:27:40.740 --> 00:27:42.362
So that means taking out the toxins.
406
00:27:43.543 --> 00:27:47.187
And also making it as easy as possible to stay on track, right?
407
00:27:47.207 --> 00:27:48.027
Where are your sneakers?
408
00:27:48.848 --> 00:27:49.509
That kind of thing.
409
00:27:49.529 --> 00:27:50.830
What are you going to do when it rains?
410
00:27:52.231 --> 00:27:55.194
And nobody has enough willpower to do this by willpower.
411
00:27:55.214 --> 00:27:58.638
So if I have chocolate ice cream in the fridge, I'm going to eat it at 8 o'clock at night.
412
00:27:58.698 --> 00:28:00.599
I don't have any more willpower than anybody else.
413
00:28:01.861 --> 00:28:06.385
But when you architect the environment so the chocolate ice cream isn't there, then you don't need it, right?
414
00:28:06.965 --> 00:28:08.346
So just things like that.
415
00:28:09.406 --> 00:28:17.049
But those five circles all interface, and that's how we get to that 3,300, 3,300 target.
416
00:28:17.790 --> 00:28:22.011
So longevity, health, performance, environment.
417
00:28:22.272 --> 00:28:23.292
I think I'm missing one.
418
00:28:23.772 --> 00:28:24.913
The life energy circle.
419
00:28:25.113 --> 00:28:25.993
Life energy circle.
420
00:28:26.153 --> 00:28:27.634
That's the one that binds them all together.
421
00:28:28.574 --> 00:28:30.575
So that's fantastic.
422
00:28:31.035 --> 00:28:35.137
Clearly in that description of the process and understanding
423
00:28:35.880 --> 00:28:39.363
is the spirituality that you've been talking since the beginning of the podcast, right?
424
00:28:39.383 --> 00:28:42.286
Like you just really, like that never went away.
425
00:28:42.306 --> 00:28:43.627
That never went away.
426
00:28:44.367 --> 00:28:53.115
And then, you know, 30-year body, 3,000-year mind, and kind of everything else you said, like that describes this symphony of coming together.
427
00:28:54.776 --> 00:28:57.078
Your book is 100 is the New 30.
428
00:28:57.698 --> 00:29:02.602
And I think a lot of that is, as you just described, optimizing the nervous system,
429
00:29:03.625 --> 00:29:05.228
some of these things interact, right?
430
00:29:05.648 --> 00:29:09.394
You're in a constant state of neuroinflammation.
431
00:29:09.454 --> 00:29:11.477
You're not going to be able to optimize your nervous system.
432
00:29:11.517 --> 00:29:17.026
If you don't have movement, you're not going to be able to like, so how do we optimize our nervous system?
433
00:29:17.872 --> 00:29:21.813
Well, it's, I'll tell you how we optimize the entire thing.
434
00:29:23.133 --> 00:29:25.174
And then I'll tell you how we optimize the nervous system.
435
00:29:25.314 --> 00:29:32.796
So, the way that medicine has been practiced is we've sliced and diced everybody up into 100 different parts, right?
436
00:29:32.816 --> 00:29:37.377
You've got a bone doctor, you've got a heart doctor, you've got a brain doctor, you've got a dermatologist, right?
437
00:29:38.397 --> 00:29:43.340
It's been a very slice and dice, and nobody's actually putting it all back together.
438
00:29:44.261 --> 00:29:50.705
You get a prescription here and one there and one there, and somebody can't figure it out, so they send you down the hall, and nobody's actually able to do it.
439
00:29:51.685 --> 00:29:59.129
So what we're doing now is deconstructing people very, very thoroughly across all five circles—
440
00:30:00.230 --> 00:30:04.631
And then we're creating a systems biology approach utilizing AI.
441
00:30:05.332 --> 00:30:12.734
So I sit on the board of an AI company that we're building, and sorry, integrated into our electronic medical record.
442
00:30:13.394 --> 00:30:25.078
We're building a systems biology to be able to look at all the circles and all the data from all the circles and weave it together in a way that creates what I call the elegant solution.
443
00:30:26.139 --> 00:30:35.615
so that we can actually have the least input into the system to push it back into its optimal state of function.
444
00:30:36.797 --> 00:30:39.402
And I'm super excited about this because...
445
00:30:40.489 --> 00:30:50.072
This is really, I think if you're listening to this and you're hearing about it, what I find when I speak with people about it is that they intuitively resonate with this.
446
00:30:50.252 --> 00:30:51.692
It's like, yeah, that's what it should be.
447
00:30:52.292 --> 00:30:53.633
You should understand me deeply.
448
00:30:54.253 --> 00:31:01.175
And then you should put it all together in an organized fashion to where one thing's not competing with another and this is counteracting that.
449
00:31:01.195 --> 00:31:01.355
Yeah.
450
00:31:02.155 --> 00:31:09.398
and I can come into harmony and into a state of, you know, real optimal function, right?
451
00:31:10.238 --> 00:31:12.299
So that's really how we're doing it.
452
00:31:12.339 --> 00:31:14.980
We're going about it with a systems biology approach.
453
00:31:15.280 --> 00:31:17.461
Hey, super quick break from the podcast.
454
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465
00:32:12.173 --> 00:32:13.034
And back to the show.
466
00:32:13.294 --> 00:32:13.714
So, yeah.
467
00:32:13.894 --> 00:32:18.836
Just kind of all the conversations that I've had, you think about this elegant solution.
468
00:32:21.797 --> 00:32:22.117
Great.
469
00:32:22.157 --> 00:32:23.477
Somebody has the elegant solution.
470
00:32:23.797 --> 00:32:29.559
How much do you have to spend with clients getting, getting them to implement it as in from the perspective of mindset?
471
00:32:30.079 --> 00:32:30.300
Yeah.
472
00:32:30.640 --> 00:32:35.241
So we, we only work with people that want to do the work, right?
473
00:32:35.261 --> 00:32:38.422
There are people that will write you a check and say, here, do it for me.
474
00:32:38.482 --> 00:32:40.043
But we know that that never works out.
475
00:32:40.543 --> 00:32:40.683
Um.
476
00:32:41.247 --> 00:32:41.487
Right?
477
00:32:41.847 --> 00:32:44.409
This is a participation game.
478
00:32:44.489 --> 00:32:45.970
Everybody's a player in this game.
479
00:32:46.650 --> 00:32:49.472
You can't just sit in the grandstands and watch it happen.
480
00:32:49.572 --> 00:32:49.792
Right?
481
00:32:49.852 --> 00:32:52.053
So we select people.
482
00:32:52.073 --> 00:32:58.517
We do personality profiles on everyone before they come in and we talk with them to make sure that they want to play.
483
00:32:58.897 --> 00:32:59.118
Right?
484
00:32:59.178 --> 00:33:01.439
If they want to play, then they're a good candidate.
485
00:33:01.479 --> 00:33:09.283
If they don't, if they just want it done for them, then we graciously decline because we know that that's never going to work out.
486
00:33:09.724 --> 00:33:09.984
So...
487
00:33:11.077 --> 00:33:11.458
Interesting.
488
00:33:11.518 --> 00:33:19.811
And then do you, I would imagine there's some supporting, uh, support for the mindset, whether, you know, techniques, processes.
489
00:33:19.831 --> 00:33:20.072
Yes.
490
00:33:20.918 --> 00:33:23.219
So back to your point about implementation.
491
00:33:23.279 --> 00:33:30.600
So when we get down to creating the elegant solution, then it's basically people that have different personalities.
492
00:33:31.260 --> 00:33:33.941
Some people want to implement a bunch of stuff all at once.
493
00:33:34.021 --> 00:33:37.042
Some people are like, no, let me just take smaller bites, right?
494
00:33:37.602 --> 00:33:43.363
So we set it up to where they can take smaller bites, and that seems to work out well for them.
495
00:33:43.755 --> 00:33:49.876
What therapies today do you think have the greatest potential to actually reverse aspects of biological aging?
496
00:33:50.756 --> 00:33:52.517
And would you call these biohacks?
497
00:33:52.737 --> 00:33:56.517
Well, I think the biohacking movement has added a lot.
498
00:33:57.277 --> 00:34:02.879
It's really brought to the forefront the idea that we can actually change the biology, right?
499
00:34:03.559 --> 00:34:05.119
So I think that's a very important piece.
500
00:34:05.559 --> 00:34:10.700
I think that biohacking is actually being superseded by systems biology.
501
00:34:11.818 --> 00:34:16.585
Because rather than trying something, trying to, oh, I'm going to hack into my brain.
502
00:34:17.126 --> 00:34:23.075
It's like, okay, well, we could try this and try that and try this combination of nootropics and whatever else.
503
00:34:23.976 --> 00:34:27.481
But the other way to do it is to have a systems biology approach that...
504
00:34:28.234 --> 00:34:37.279
where it's like, let's deconstruct your brain, let's deconstruct your gut, let's look at your whole situation here, let's look at your nervous system for that matter, right, how stressed you are, etc.
505
00:34:38.079 --> 00:34:43.962
Once we break all that down, then the goal is, you know, how good can my brain be, right?
506
00:34:44.523 --> 00:34:51.046
But now we have many leverage points, right, to work with, not just let's try nootropic and see what it does, right?
507
00:34:52.036 --> 00:34:58.440
and sometimes we find that what the brain needs is actually more calming down, that it needs more stimulants per se, right?
508
00:34:59.040 --> 00:35:03.043
So it's the system's approach that will always win the day.
509
00:35:03.183 --> 00:35:09.848
We find a lot of people are hypothyroid, they don't know their hypothyroid, or they can't convert inactive thyroid to active thyroid in their brain.
510
00:35:09.948 --> 00:35:12.790
Once we get that fixed, the lights come on for them.
511
00:35:13.370 --> 00:35:20.154
So the problem with biohacking is that it's fascinated by interventions
512
00:35:21.836 --> 00:35:34.686
When in actual fact, the true fascination is in the deconstruction of the individual to actually understand who they are and what interventions are most likely to be the most helpful to them based on an integrated view of everything.
513
00:35:35.467 --> 00:35:40.671
And that we find much more deeply satisfying than say, hey, try this and see if it works for you.
514
00:35:41.231 --> 00:35:43.853
Or I've got this, oh, I know something that'll help that, you know.
515
00:35:44.473 --> 00:35:49.956
So it's a little bit of a function of medicine in general, right?
516
00:35:49.976 --> 00:35:52.838
There's a symptom, oh, here's the solution, right?
517
00:35:52.858 --> 00:35:54.659
A little bit of testing, but here's the solution.
518
00:35:54.739 --> 00:35:56.941
And there's just a quiver of, you know,
519
00:35:57.741 --> 00:35:58.941
finite number of solutions.
520
00:35:59.621 --> 00:36:02.802
So when you see your doctor, they've only got 10 things they can give you.
521
00:36:03.062 --> 00:36:03.922
Well, which one are we?
522
00:36:04.082 --> 00:36:06.563
Oh, well, based on that, we'll give you this, right?
523
00:36:07.283 --> 00:36:13.984
So in a systems approach, it's really the big deconstruction followed by the, oh, well, this is the reason you have that in the first place.
524
00:36:14.364 --> 00:36:19.745
And actually, genetically, if we modify the way these genes are expressed, this probably goes away in the first place.
525
00:36:19.966 --> 00:36:22.566
You don't even need anything else beyond that, right?
526
00:36:22.646 --> 00:36:26.107
So there's a certain elegance to the whole process here.
527
00:36:27.961 --> 00:36:34.063
The thing I like about it too is people get excited about it because they understand for the first time that they're being deeply understood.
528
00:36:34.203 --> 00:36:37.244
And people really, all of us want to be deeply understood.
529
00:36:37.904 --> 00:36:42.986
And it gives them confidence in the recommendations because they know the recommendations are custom fit to them.
530
00:36:44.186 --> 00:36:45.687
They're not generic recommendations.
531
00:36:46.627 --> 00:36:54.593
And that enables them to have, let's call it the willpower or the staying power to want to implement whatever we're asking them to do.
532
00:36:54.653 --> 00:36:59.477
And again, we, you know, sort of trickle that in or push that in at the rate at which they want to receive it.
533
00:37:00.217 --> 00:37:02.179
So, yeah, so that's kind of how that works.
534
00:37:02.199 --> 00:37:11.846
So I think biohacking has really served us well, but I think it's about to be superseded by systems biology, which AI is making possible.
535
00:37:12.066 --> 00:37:20.468
I think the therapies that are the most interesting are the ones that focus on the nervous system, because that ends up controlling so much of everything else.
536
00:37:21.228 --> 00:37:26.510
Then I think I'm also very intrigued by all the regenerative technologies we have at our disposal.
537
00:37:27.190 --> 00:37:33.592
And again, we know they work better, not as a standalone product, but as part of a process.
538
00:37:34.512 --> 00:37:41.698
And so understanding that stem cells may be great, but stem cells alone are not all that wonderful.
539
00:37:42.539 --> 00:37:47.683
It's kind of like if you're throwing magic seeds onto the sidewalk, they're not going to grow very well.
540
00:37:47.783 --> 00:37:49.244
You have to prepare the soil.
541
00:37:49.324 --> 00:37:49.825
You have to...
542
00:37:50.365 --> 00:37:51.886
prepare the seeds for that matter.
543
00:37:51.926 --> 00:37:53.727
Then you've got to support them afterwards.
544
00:37:53.787 --> 00:38:08.957
And so there's a whole process that we go through to actually cause regeneration for people where we're pruning senescent cells, getting rid of the inflammation that's in their system, putting in the regenerative factors, multiple types of regenerative factors that support
545
00:38:09.697 --> 00:38:25.801
what we're trying to accomplish, and then support it later on afterwards with peptides and red light and laser and energetics, things that will actually electrical stem, things that will actually get them better results than if they just got a particular product.
546
00:38:25.961 --> 00:38:28.221
You'd also ask about the symphony of longevity.
547
00:38:28.962 --> 00:38:32.302
Part of that particular is related to the longevity circle,
548
00:38:40.065 --> 00:38:49.440
you know, something needs to be pulled or activated to optimize it, there's actually a timing and a sequence, there's a frequency, intensity and duration with which those levers get pulled.
549
00:38:50.162 --> 00:38:52.926
And so therein lies the symphony of longevity.
550
00:38:52.966 --> 00:38:53.748
It's very musical.
551
00:38:54.103 --> 00:39:03.226
So I hear you talking about systems, and I think back to the kind of earlier part of this podcast where you're talking about interventional cardiologists, nuclear cardiologists.
552
00:39:03.246 --> 00:39:07.407
I think there was one other cardiologist where you just like the entire approach.
553
00:39:07.547 --> 00:39:14.650
You just have to be happy as a clam as you come in and work with clients on this broad-based systems experience.
554
00:39:14.670 --> 00:39:16.150
I can't imagine otherwise.
555
00:39:16.770 --> 00:39:17.951
Yeah, that's exactly right.
556
00:39:18.011 --> 00:39:18.991
It's exciting, right?
557
00:39:19.011 --> 00:39:20.972
Because when you're...
558
00:39:22.452 --> 00:39:26.974
When you're married to the questions and not the current answers, life is very exciting.
559
00:39:28.375 --> 00:39:32.756
So for us, I mentioned before that, you know, how good can we be is a question.
560
00:39:32.857 --> 00:39:34.337
How do we make 100 to new 30?
561
00:39:34.457 --> 00:39:37.238
How do we live well beyond 120 is another question.
562
00:39:37.919 --> 00:39:41.800
That's a theoretical limit for how long a human can live based on telomere shortening.
563
00:39:42.261 --> 00:39:44.562
How do we live young for a lifetime, right?
564
00:39:44.582 --> 00:39:47.443
That's how we stay youthful, enthusiastic, curious.
565
00:39:47.703 --> 00:39:48.723
You know, I want to try that.
566
00:39:48.883 --> 00:39:49.544
I want to do this.
567
00:39:50.944 --> 00:39:55.608
As people age, they tend to narrow their range of activities, right?
568
00:39:55.788 --> 00:39:57.089
And their friends and everything else.
569
00:39:57.109 --> 00:39:58.410
Like, no, let me meet new people.
570
00:39:58.430 --> 00:39:59.030
Let me try that.
571
00:39:59.050 --> 00:40:00.011
I've never did that before.
572
00:40:00.452 --> 00:40:01.512
I want to try that, right?
573
00:40:01.532 --> 00:40:03.154
That live young for a lifetime.
574
00:40:03.674 --> 00:40:05.675
And then how do we develop the 300, 3000-year-old mind
575
00:40:07.977 --> 00:40:09.258
which you had asked about earlier.
576
00:40:09.898 --> 00:40:12.799
And those five questions drive everything we do here.
577
00:40:12.819 --> 00:40:19.822
So even though we have thousands of answers here that I never knew as a traditional physician, we're not married to a single one.
578
00:40:20.322 --> 00:40:21.762
We're only married to the questions.
579
00:40:22.002 --> 00:40:33.247
And that gets us excited every day to come into work because we're learning stuff at such a pace and implementing things, new things at such a pace that it's just like, how much fun can you have?
580
00:40:34.067 --> 00:40:35.148
And we're helping so many people.
581
00:40:35.188 --> 00:40:35.848
It's really wonderful.
582
00:40:37.055 --> 00:40:44.466
How do you see, because you mentioned 120, right, kind of the theoretical from a telemere perspective, how do you see us manipulating that?
583
00:40:44.486 --> 00:40:45.848
Do you think we have the tools already?
584
00:40:46.048 --> 00:40:47.149
Are the tools around the corner?
585
00:40:47.169 --> 00:40:47.290
We do.
586
00:40:47.928 --> 00:40:52.231
We have tools right now that can help with that.
587
00:40:52.331 --> 00:41:07.159
Everything from genetic implants for optimizing telomere re-lengthening to some really interesting data on psilocybin, which has been shown to lengthen telomeres now, to different supplements.
588
00:41:07.459 --> 00:41:09.521
Decreasing stress is a massive driver.
589
00:41:09.681 --> 00:41:14.223
Remember, I said that stress is a massive driver of all 12 of those hallmarks of aging.
590
00:41:14.343 --> 00:41:16.225
And one of those, of course, is telomere shortening.
591
00:41:17.265 --> 00:41:23.068
And what happens when the telomeres get short, the cell is basically informed that it's now old and it should stop working.
592
00:41:23.108 --> 00:41:37.476
So, it just sits there and takes up space, but it gets worse because now it expands in size, so tissues get stiff, and that gets worse again because it starts to spew out these inflammatory cytokines that increase cancer risk and recruit other cells to become senescent.
593
00:41:37.896 --> 00:41:41.158
And so, this is an accelerating process.
594
00:41:41.879 --> 00:41:42.219
I think...
595
00:41:43.025 --> 00:41:46.627
It's really important for people to understand that aging is an exponential process.
596
00:41:47.548 --> 00:41:50.329
So you are in an exponential game, right?
597
00:41:50.809 --> 00:41:56.152
People age so much more between 70 and 80, 80 and 90 than between 20 and 30 and 30 and 40, right?
598
00:41:56.613 --> 00:41:57.333
We all know that.
599
00:41:57.473 --> 00:42:00.635
But if we ask ourselves, geez, what am I going to be like 20 years from now?
600
00:42:01.295 --> 00:42:05.738
Chris, if you ask yourself that or if you're listening, if you ask yourself, what am I going to be like 20 years from now?
601
00:42:07.355 --> 00:42:11.198
It's almost impossible to imagine you're going to be any different than you are today, right?
602
00:42:11.498 --> 00:42:11.718
Yeah.
603
00:42:12.158 --> 00:42:16.421
So we're in a game of exponential decline that we have a hard time relating to.
604
00:42:16.641 --> 00:42:22.685
And if you don't have an exponential strategy, you're biohacking, you're whatever you're doing.
605
00:42:22.745 --> 00:42:24.066
I'm getting hormone replacement.
606
00:42:24.086 --> 00:42:24.847
I'm doing peptides.
607
00:42:24.887 --> 00:42:25.707
Those are wonderful.
608
00:42:25.747 --> 00:42:26.428
We love all that.
609
00:42:26.488 --> 00:42:29.410
But those are linear responses to an exponential problem.
610
00:42:30.454 --> 00:42:37.436
What's required to have an exponential response to an exponential problem is a systems biology approach across all five of those circles.
611
00:42:38.556 --> 00:42:41.717
When you do that, now you actually have an exponential response.
612
00:42:42.157 --> 00:42:46.539
Now you're actually can make good on, you know, what you want to accomplish.
613
00:42:46.899 --> 00:42:49.600
And that's why that gets us excited as well.
614
00:42:49.960 --> 00:42:51.980
So, we talked early, right?
615
00:42:52.000 --> 00:42:57.402
Your maternal grandmother, your mom, it's hell to get old, you don't ever want to get old.
616
00:42:58.657 --> 00:43:08.105
Usually these are just phrases you hear and you internalize them and you don't process them, although you were processing things at three that normal people aren't necessarily processing.
617
00:43:08.706 --> 00:43:13.269
When did you really kind of settle in on this and understand, okay, that's not true.
618
00:43:13.370 --> 00:43:15.992
I just don't fundamentally believe it.
619
00:43:17.893 --> 00:43:20.976
Well, I think I always held it in my mind.
620
00:43:21.036 --> 00:43:25.340
And of course, my older sister with her brain damage, um...
621
00:43:26.424 --> 00:43:36.928
you know, was also seeing the impact of loss of health in someone that was, you know, my sibling, my peer, if you will, right?
622
00:43:38.008 --> 00:43:40.149
And I could see how she struggled, right?
623
00:43:40.309 --> 00:43:42.129
She ended up, her IQ was about 50.
624
00:43:42.209 --> 00:43:46.791
She was very gregarious, athletic, musical, wonderful.
625
00:43:46.851 --> 00:43:48.932
She probably knew more people than my parents did, right?
626
00:43:50.852 --> 00:43:54.614
Everybody loved Linda, but yet I saw her struggle.
627
00:43:54.994 --> 00:43:56.835
And then I heard my grandmother talking about this.
628
00:43:56.895 --> 00:44:02.057
And I started to realize from a young age that losing health capacity is a big deal.
629
00:44:03.252 --> 00:44:04.253
It's a really big deal.
630
00:44:04.513 --> 00:44:06.475
And now people are actually suffering from it.
631
00:44:06.875 --> 00:44:12.379
Because when she would say it's hell to get old, it's not because she just couldn't do what she used to.
632
00:44:12.419 --> 00:44:15.221
It's like she's suffering from things, right?
633
00:44:16.582 --> 00:44:17.803
And my mom, the same way.
634
00:44:17.983 --> 00:44:19.184
People actually suffer.
635
00:44:19.884 --> 00:44:24.408
So people talk about, well, the expense of staying youthful and healthy.
636
00:44:24.588 --> 00:44:24.948
Well, yeah.
637
00:44:26.135 --> 00:44:29.517
What we underestimate is the cost of not being healthy, right?
638
00:44:30.077 --> 00:44:40.402
Not only in terms of financial burden or loss of income potential or business opportunities, but also just the loss of, you know, being pain-free, right?
639
00:44:41.638 --> 00:44:48.264
Uh, it's, there's a big, there's a massive price to pay for going down that exponential decline of aging.
640
00:44:48.864 --> 00:44:57.551
And we think that the investment of time, attention, and resources into developing an exponential strategy is really the sanest thing that anybody could do.
641
00:44:58.071 --> 00:45:00.093
Um, and I don't fear death.
642
00:45:00.133 --> 00:45:04.737
Quite honestly, if I killed a day on the drive home from the office, it's been an incredible life.
643
00:45:04.777 --> 00:45:05.537
It's been amazing.
644
00:45:05.577 --> 00:45:05.838
Right.
645
00:45:06.518 --> 00:45:08.600
But I don't want to go into decline.
646
00:45:08.900 --> 00:45:09.140
Right.
647
00:45:09.380 --> 00:45:09.801
Uh, yeah.
648
00:45:10.321 --> 00:45:13.102
And even in decline, I would find the gift that was there.
649
00:45:13.342 --> 00:45:15.963
But I really enjoy being able to do whatever I want.
650
00:45:16.963 --> 00:45:18.444
And, you know, that's a good thing.
651
00:45:18.564 --> 00:45:19.784
Again, I was born in 54.
652
00:45:19.804 --> 00:45:21.165
I wake up 27 every day.
653
00:45:21.785 --> 00:45:22.525
So it's good.
654
00:45:23.485 --> 00:45:24.786
That's fantastic.
655
00:45:24.806 --> 00:45:27.327
So maybe the phrase, it's hell to get old.
656
00:45:27.387 --> 00:45:31.848
You don't ever want to get old is really actually being unhealthy as hell.
657
00:45:32.288 --> 00:45:34.289
You don't ever want to get unhealthy.
658
00:45:34.309 --> 00:45:36.349
That's well stated.
659
00:45:36.469 --> 00:45:36.910
That's right.
660
00:45:37.430 --> 00:45:37.870
That's right.
661
00:45:38.030 --> 00:45:38.250
All right.
662
00:45:39.135 --> 00:45:46.058
And that actually has a parallel of a product that's responsible for the single longest longevity experimental result on mammals in history.
663
00:45:46.659 --> 00:45:47.959
And I share the story.
664
00:45:48.019 --> 00:45:51.101
And often people were saying, why would I want to live longer?
665
00:45:51.121 --> 00:45:52.922
And that took me a while to process.
666
00:45:52.942 --> 00:45:54.802
I've always had like 125 in my head.
667
00:45:54.842 --> 00:45:55.523
I don't know why.
668
00:45:55.543 --> 00:45:58.284
I don't know where I got the number, but, you know, a nice round number.
669
00:45:58.824 --> 00:46:00.325
And so I didn't understand what they were saying.
670
00:46:00.365 --> 00:46:06.288
And it took me a while to understand if you ask somebody, and this goes back to the debatable comment you had earlier,
671
00:46:07.148 --> 00:46:12.912
if you ask somebody, hey, they can't separate living infirmed from living longer, right?
672
00:46:13.052 --> 00:46:21.278
And so you ask somebody to live longer, what they hear is how much longer in some state and potentially declining state of infirmed would you like to live?
673
00:46:21.399 --> 00:46:25.482
And yeah, the answer is absolutely debatable and often not that long.
674
00:46:25.822 --> 00:46:26.322
That's right.
675
00:46:26.943 --> 00:46:33.968
But you're changing the question to, Dr. Gladden, if you had the same mental capacity that you had today, actually at 30,
676
00:46:34.682 --> 00:46:40.667
And the same physical capacity that you have today, in your case, actually at 30, would you then be interested in living longer?
677
00:46:40.767 --> 00:46:43.049
And that's where things really start to change.
678
00:46:43.089 --> 00:46:44.611
I'm really excited about this.
679
00:46:44.651 --> 00:46:49.175
So your practice, I don't know if any of that resonated, if you wanted to make any comments.
680
00:46:49.315 --> 00:46:50.516
No, that's exactly right.
681
00:46:50.736 --> 00:46:51.417
Yeah, that's right.
682
00:46:52.077 --> 00:46:56.801
So your practices in Dallas, talk about your kind of typical clients, the results you're striving for.
683
00:46:56.841 --> 00:46:58.563
You've certainly touched on a lot of it.
684
00:46:59.624 --> 00:47:02.066
And then we'll get into our wrap-up questions.
685
00:47:02.086 --> 00:47:02.206
Yeah.
686
00:47:02.455 --> 00:47:08.177
Yeah, so typical clients are people that have a lot to live for, right?
687
00:47:08.377 --> 00:47:20.261
They may be a business owner, an entrepreneur, a family person, somebody that typically is not looking to retire from a job.
688
00:47:20.962 --> 00:47:24.183
If they are going to leave something, they're going to transition into the next thing.
689
00:47:25.650 --> 00:47:27.951
If they're going to sell a company, they're going to start two more.
690
00:47:29.692 --> 00:47:31.773
It's not really a strategy of slowing down.
691
00:47:32.473 --> 00:47:43.117
Because the interesting thing is that while aging is exponentially, is an exponential decline across the decades, our opportunities and our impact are.
692
00:47:44.207 --> 00:47:47.429
is increasing exponentially across the decades, right?
693
00:47:47.449 --> 00:47:50.591
You have more impact and opportunity now than you did 10 years ago.
694
00:47:50.891 --> 00:47:53.872
And you had 10 years ago more than you did 10 years prior to that, right?
695
00:47:54.553 --> 00:48:08.220
So if you extrapolate that curve, when the lines cross, decline and upswing of opportunity and impact, you know, you can carry on for a little bit, but then you kind of crater and people are coming to see you in a nursing home.
696
00:48:08.240 --> 00:48:09.401
That's the fate we don't want.
697
00:48:10.041 --> 00:48:12.803
But if you stay young, right, and...
698
00:48:13.483 --> 00:48:15.506
This is what resonates with the people that join us.
699
00:48:15.586 --> 00:48:27.719
If you live young at, let's say, 30 or whatever they want to be, that exponential increase in opportunity and impact continues to go up, particularly when you develop the 300, 3000-year-old mind.
700
00:48:27.760 --> 00:48:34.067
Now it expands out into all kinds of things that they only imagined could be possible, right?
701
00:48:34.427 --> 00:48:36.048
And that's very exciting to them.
702
00:48:36.509 --> 00:48:39.471
And so they double down on, oh, I want to invest in that, right?
703
00:48:39.491 --> 00:48:43.374
I invest in a lot of companies and people, but I'm going to invest in myself.
704
00:48:43.934 --> 00:48:45.516
I want to invest in that future.
705
00:48:46.706 --> 00:48:51.772
And we're a bargain, quite honestly, when you look at the return on investment for that.
706
00:48:52.413 --> 00:49:08.170
And so it's people that have the ability to see a different future and understand that they could be having more impact, opportunity, experiencing more love, more joy, having more fun than they've ever had.
707
00:49:09.560 --> 00:49:14.984
if they basically have the youthfulness to support it and they have this expanded perspective on how to live it.
708
00:49:15.664 --> 00:49:18.507
So that's, that's, those are the people that, that sign up.
709
00:49:18.967 --> 00:49:19.147
Yeah.
710
00:49:20.230 --> 00:49:30.053
That sounds like very, again, fulfilling for you to deliver and seems like a no-brainer from the – that's what people want to experience.
711
00:49:30.613 --> 00:49:33.314
Before we get into wrap-up, is there maybe something we didn't touch on?
712
00:49:33.354 --> 00:49:39.696
I think that's actually a pretty good summary, but I want to give you the opportunity if there's a summary or anything we didn't touch on that you were hoping to touch on.
713
00:49:39.716 --> 00:49:41.477
Yeah, I think –
714
00:49:43.250 --> 00:49:52.815
I think if you're listening to this, just ask yourself, you could actually do this as a mental exercise, what am I going to be like in 20 years from now?
715
00:49:53.215 --> 00:50:00.099
Actually map that out and base it on peer groups and your own family and all that kind of stuff.
716
00:50:00.139 --> 00:50:03.601
What happened to people when they were 20 years older than you are today?
717
00:50:04.061 --> 00:50:07.503
25, 10, 15, 30 years older than you are today, what did that look like?
718
00:50:08.483 --> 00:50:11.325
And then ask yourself, is that where I want to go?
719
00:50:12.487 --> 00:50:15.409
And if the answer is yes, then, you know, more power to you.
720
00:50:15.589 --> 00:50:25.314
But if the answer is no, I'd like a different future, then ask yourself, do I have an exponential strategy for the exponential problem of aging?
721
00:50:25.434 --> 00:50:26.475
Because it's not linear.
722
00:50:26.495 --> 00:50:29.416
Chronologically, it's linear, but biologically, it's exponential.
723
00:50:30.517 --> 00:50:37.861
And if you don't have an exponential strategy, then it's like, oh, well, maybe I need to rethink this and maybe...
724
00:50:39.722 --> 00:50:41.924
It's possible because I think we live in it.
725
00:50:42.084 --> 00:50:46.968
We're the luckiest generation of all time because we live in a day and age where actually aging is being solved.
726
00:50:47.768 --> 00:50:53.172
And it's going to be completely solved inside of a systems biology approach, not in a biohacking approach.
727
00:50:53.312 --> 00:50:54.373
God bless biohackers.
728
00:50:54.393 --> 00:50:55.274
They've done a lot of good.
729
00:50:55.814 --> 00:50:58.656
But it's going to be inside of a systems biology approach.
730
00:50:59.016 --> 00:51:01.839
And then ask yourself, is that what I have currently working for me?
731
00:51:02.139 --> 00:51:03.240
And if it is, great.
732
00:51:03.440 --> 00:51:05.942
If it isn't, then think about how you can get that.
733
00:51:06.262 --> 00:51:06.362
Yeah.
734
00:51:06.382 --> 00:51:06.482
Yeah.
735
00:51:07.604 --> 00:51:07.905
Excellent.
736
00:51:08.025 --> 00:51:08.286
All right.
737
00:51:08.526 --> 00:51:09.809
Time for our wrap up questions.
738
00:51:09.949 --> 00:51:12.654
Dr. Gladden, do you have a target age that you want to live to?
739
00:51:14.966 --> 00:51:16.487
You know, that's an interesting question.
740
00:51:16.547 --> 00:51:20.310
I have more of a target age of how I want to function.
741
00:51:21.331 --> 00:51:23.032
Like, I'm 27 now.
742
00:51:23.052 --> 00:51:27.256
I'll be 27 this decade, 28 the next, 29 the next, and 30 when I'm 100.
743
00:51:28.016 --> 00:51:37.083
So I'm more focused on maintaining youthfulness than I am looking forward to a particular age.
744
00:51:37.103 --> 00:51:37.944
And I'll tell you why.
745
00:51:38.224 --> 00:51:40.726
Because those ages are all abstract to me.
746
00:51:42.383 --> 00:51:45.784
I want to be 120, 150, 180, 300, 780.
747
00:51:45.824 --> 00:51:47.425
That's a complete abstraction.
748
00:51:47.865 --> 00:51:52.987
I don't even know what that would feel like, but I do know what it is to be 27, what it is to be 30.
749
00:51:53.668 --> 00:52:01.851
And if I can maintain that for a long time, I'm much more invested in that than I am the actual number that takes me to, if you will.
750
00:52:02.871 --> 00:52:03.351
Excellent.
751
00:52:03.451 --> 00:52:07.553
And you are constantly working on the solutions to aging.
752
00:52:08.709 --> 00:52:09.710
That opens the door.
753
00:52:10.371 --> 00:52:18.037
How long, and this may be a two, I always think of this, at least for myself, as a two-part answer, which is how long do you think humans can live?
754
00:52:18.057 --> 00:52:23.001
And I always give the answer like today numbers and then, you know, whatever, 10 year from now numbers.
755
00:52:23.982 --> 00:52:28.645
Yeah, I mean, I think death is, I'm not an immortalist, right?
756
00:52:28.665 --> 00:52:30.667
So it's not like I want to live forever.
757
00:52:32.048 --> 00:52:36.131
I do think that we're going to
758
00:52:37.383 --> 00:52:49.532
I think we're going to crack the code on aging within the next 12 months because really when you combine AI, quantum AI, when you combine systems biology, we're knocking on the door.
759
00:52:49.612 --> 00:52:54.715
The rate of which therapies are coming forward, I really believe it's going to be cracked in the next 12 months.
760
00:52:54.775 --> 00:52:58.017
I said two years ago it would be three years, and I think that's pretty much on target.
761
00:53:00.318 --> 00:53:10.080
So, once it's cracked, then the question is, well, initially, who can afford it, right, because it'll be expensive at first, and then it will become more and more affordable.
762
00:53:10.240 --> 00:53:11.721
And we're working to democratize it.
763
00:53:11.801 --> 00:53:13.781
Part of this is democratizing his thoughts.
764
00:53:14.601 --> 00:53:17.602
But then I think it becomes a question of how long you want to live.
765
00:53:17.882 --> 00:53:21.123
And I think we'll get to a point where you can actually choose.
766
00:53:21.963 --> 00:53:23.584
you know, pretty much how long you want to go.
767
00:53:24.925 --> 00:53:28.808
I don't think biology, I don't know if we're living a thousand years or 600 years.
768
00:53:28.868 --> 00:53:29.969
I don't know what that would mean.
769
00:53:31.150 --> 00:53:35.533
You know, there are lots of things that have to do with friends and sociability and purpose and meaning.
770
00:53:35.593 --> 00:53:39.276
And if that gets lost, you know, then people are going to lose their will to live.
771
00:53:40.918 --> 00:53:46.602
But I think we will have the option to live young for a lifetime.
772
00:53:47.162 --> 00:53:49.944
And I don't know what that takes us to, but I think it'll be, you know,
773
00:53:50.885 --> 00:53:52.326
selectable by each individual.
774
00:53:53.768 --> 00:53:54.088
Excellent.
775
00:53:54.328 --> 00:54:03.897
Dr. Gladden, what are two to three protocols, habits, mindsets, let's call them shortcuts because everybody likes shortcuts, to a long health span and longevity that you could share?
776
00:54:04.185 --> 00:54:06.728
Well, I think the number one thing is stress.
777
00:54:07.890 --> 00:54:15.199
Stress really sabotages everything from sleep to hormonal health to brain health to memory to gut health.
778
00:54:15.920 --> 00:54:21.567
And I think you'd asked earlier in the podcast about how we help people optimize the nervous system.
779
00:54:23.024 --> 00:54:26.285
I think one of the best ways to do that is to learn how to meditate.
780
00:54:27.845 --> 00:54:30.326
And meditation is a little bit like riding a bike, right?
781
00:54:30.386 --> 00:54:33.987
Because when you first try it, it's like, I'm not sure I can get in this.
782
00:54:34.047 --> 00:54:34.907
I keep falling off.
783
00:54:34.947 --> 00:54:38.828
I can't really clear my brain of thoughts and things like that, right?
784
00:54:39.368 --> 00:54:44.529
So even in that attempt, we realize that we don't really control our nervous system, right?
785
00:54:44.609 --> 00:54:46.930
Thoughts are coming in, whether we want them to or not.
786
00:54:46.970 --> 00:54:48.690
It's like, well, I don't really have control over that.
787
00:54:49.170 --> 00:54:51.431
Well, you can get control over that, right?
788
00:54:52.071 --> 00:54:57.076
And if you start learning how to meditate, and I think there are great ways to learn that.
789
00:54:57.096 --> 00:54:59.399
There are a lot of different haps that will coach people on things.
790
00:54:59.419 --> 00:55:05.745
There's binaural beach, which is a little different frequency in each year that will help push you into a meditative state.
791
00:55:05.805 --> 00:55:13.433
Things like brain tap that uses photobiomodulation along with binaural beats can really take you into a meditative space.
792
00:55:13.853 --> 00:55:15.214
But if you double down on...
793
00:55:15.775 --> 00:55:21.598
trying to put yourself into a theta state, that's a brainwave frequency, theta, T-H-E-T-A.
794
00:55:22.658 --> 00:55:32.063
If you do that twice a day for about 10 minutes, you'll be stunned that you actually start to develop a sense of control over your mind.
795
00:55:32.403 --> 00:55:40.707
And from there, then it's asking bigger questions like, how do I actually give myself safety if nothing external to me can ever make me feel safe, right?
796
00:55:41.608 --> 00:55:43.515
How do I give myself unconditional love?
797
00:55:43.635 --> 00:55:46.325
How do I heal the traumas that I'm living in reaction to?
798
00:55:47.305 --> 00:55:51.528
How do I transcend them and become grateful for everything that ever happened?
799
00:55:51.548 --> 00:55:57.271
Because everything is maybe a wiser, more loving, more empathetic human being.
800
00:55:58.112 --> 00:56:08.438
When you start to really transform that, and I write about this extensively in the book, 100 is the New 30, then all of a sudden you get a completely different perspective on life.
801
00:56:09.079 --> 00:56:13.001
And it's not that you get less done, you actually get more done, but you don't have to stress to do it.
802
00:56:13.852 --> 00:56:19.556
And when you take stress out of the system, that is probably the biggest hack that you can possibly make.
803
00:56:20.196 --> 00:56:26.400
Then all the usual things, you know, sleep, eating well, clean water, exercise, those are all givens, right?
804
00:56:26.640 --> 00:56:27.621
They're basically givens.
805
00:56:27.701 --> 00:56:30.122
It's table stakes.
806
00:56:30.503 --> 00:56:34.925
But to control the nervous system, that's the piece that a lot of people miss.
807
00:56:34.945 --> 00:56:37.107
Excellent.
808
00:56:37.127 --> 00:56:37.467
Excellent.
809
00:56:39.098 --> 00:56:45.137
Dr. Gladden, what are one or two things you think people get absolutely wrong regarding longevity in a long health span?
810
00:56:46.313 --> 00:56:55.979
I think one of the things that I see is people trying things because their neighbor tried it without understanding whether or not it's the right thing for them.
811
00:56:56.239 --> 00:56:57.200
I think that's one way.
812
00:56:58.160 --> 00:57:06.766
I think the other thing that people get wrong is that they look at a technology, let's call it stem cells, and they think, I'm going to go get stem cells because I've read that those are really good.
813
00:57:07.746 --> 00:57:12.609
And they don't realize that regeneration is not a product, it's a process.
814
00:57:12.629 --> 00:57:12.729
Yeah.
815
00:57:13.816 --> 00:57:19.661
And that in order for those stem cells to work, you have to go through the steps to prepare your body to receive them.
816
00:57:20.041 --> 00:57:29.809
Because if you put young stem cells into a Petri dish full of old plasma, right, that's full of inflammatory markers from these senescent cells, etc., they don't do much at all.
817
00:57:29.989 --> 00:57:30.670
They die out.
818
00:57:31.858 --> 00:57:35.640
And so you've got to clean up the environment before it's like a farmer.
819
00:57:35.660 --> 00:57:38.961
You've got to clean up the field before you plant the seeds.
820
00:57:39.021 --> 00:57:41.563
And then you've got to plant them along with other things, right?
821
00:57:41.623 --> 00:57:48.846
Like cord blood factors and placental factors and other very youthful factors that help those stem cells do what they're supposed to do.
822
00:57:49.486 --> 00:57:50.647
So they're signaled properly.
823
00:57:50.667 --> 00:57:58.090
And then you've got to support them with peptides and things like laser and red light and, you know, electrical fields that help stimulate growth.
824
00:57:58.150 --> 00:58:02.372
And all of a sudden, you can get remarkable results, but not just from the stem cells.
825
00:58:02.432 --> 00:58:05.673
It's the process, not the product that you need to focus on.
826
00:58:05.753 --> 00:58:12.176
And if you're going to see someone and they're only going to give you an injection of the product with no process,
827
00:58:13.336 --> 00:58:16.858
then you're only going to get one-tenth of the result that you could.
828
00:58:17.318 --> 00:58:25.143
And then if you layer on the nervous system on top of that, you can see how you can get very powerful results if you have your nervous system under control and you're doing the right process.
829
00:58:25.663 --> 00:58:27.445
So I see people get that run a lot.
830
00:58:28.505 --> 00:58:28.845
Excellent.
831
00:58:29.426 --> 00:58:31.387
Dr. Gladden, how can people contact you?
832
00:58:32.612 --> 00:58:36.035
They can get us through the website, gladinlongevity.com.
833
00:58:37.596 --> 00:58:39.398
All the social media things will be on there.
834
00:58:40.359 --> 00:58:42.841
The podcast is on there, Glad Longevity podcast.
835
00:58:42.861 --> 00:58:50.527
But if you just go to gladinlongevity.com, you can reach out to us if you want to have a conversation about any of this, or we'd be happy to chat.
836
00:58:50.987 --> 00:58:53.129
And yeah, that's the best way to go.
837
00:58:54.010 --> 00:58:54.290
Excellent.
838
00:58:54.330 --> 00:58:56.412
And what in the near future are you excited about?
839
00:58:57.797 --> 00:59:01.878
I'm excited about the AI that we're building right now with the systems biology in it.
840
00:59:02.139 --> 00:59:03.419
I'm so excited about that.
841
00:59:03.639 --> 00:59:06.420
It's like a dream come true, right?
842
00:59:06.520 --> 00:59:08.281
I've been thinking about this for a long time.
843
00:59:08.521 --> 00:59:23.046
And to actually have it and be able to apply it to individuals to find those elegant solutions and those really deeply well thought out solutions that are custom fit to the individual, that's super exciting to me, right?
844
00:59:24.226 --> 00:59:24.527
Excellent.
845
00:59:24.827 --> 00:59:34.414
You can find him, so his podcast on social media, just contacting him about his services, gladdenlongevity.com.
846
00:59:35.394 --> 00:59:37.796
Dr. Gladden, thank you so much for joining us today.
847
00:59:38.276 --> 00:59:39.197
Yeah, my pleasure, Chris.
848
00:59:39.497 --> 00:59:40.218
Great to chat with you.
849
00:59:41.323 --> 00:59:44.786
I hope you enjoyed this episode of the Live Beyond the Norms podcast.
850
00:59:45.326 --> 00:59:47.108
Make sure to subscribe and follow.
851
00:59:47.708 --> 00:59:55.094
Also, make sure not to be that guy, the guy sharing this podcast with people who are not interested in living beyond the norms.
852
00:59:55.815 --> 01:00:07.285
If you would like to learn more about the ESS60 molecule, the molecule responsible for the single longest longevity experimental result on mammals in history, a full 90% extension of life.
853
01:00:07.865 --> 01:00:09.968
visit myvitalc.com.
854
01:00:10.509 --> 01:00:13.653
That's myvitalc as in carbon.com.