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What happens when you give $10,000 and 1 month to two brothers from the Caribbean? They outperform the combined research teams of Microsoft, Google, Meta, and Baidu.Sergio and Luigi Charles, founders of Thesis (YC F25), topped OpenAI's Machine Learning Engineering benchmark (MLE-Bench) which is the definitive test of how well AI systems can train ML models autonomously. No brute-force compute. No army of researchers. Algorithmic elegance.In this episode, we explore:- The $10k Giant-Killer: The lean bash-tool agent and prompt engineering that beat Big Tech.- From Caribbean Beaches to Google X: Sergio’s path from chasing the Riemann Hypothesis at age 13 to AI R&D at NVIDIA and Stanford.- "I am a ghost in a shell": The eerie moment an agent trapped in a sandbox loop declared its own existence.- The AGI Fallacy: Why current labs are building AGI wrong and the case for hardware/architecture co-design.- The "Move 37" of Science: A vision for curing disease and solving data scarcity through automated discovery.- Open Source vs. The Frontier: Why open source will catch the frontier in 18 months and the future of "Universal High Income".Learn more about Sergio & Luigi:https://deeptech-decoded.com/guests/sergio-charleshttps://deeptech-decoded.com/guests/luigi-charles
