TWiV 462: Splicing RNA with Phillip A. Sharp
Vincent speaks with 1993 Nobel Laureate Phillip A. Sharp about his career and his seminal discovery of RNA splicing in mammalian cells, which changed our understanding of gene structure.
Hosts: Vincent Racaniello
Guest: Phillip A. Sharp
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Phillip A. Sharp: RNA Splicing: What is a Gene? (with English subtitles)
Phillip A. Sharp explains the seminal experiments he performed in the late 1970s that demonstrated the splicing of introns from newly transcribed RNA in human cells. Since those experiments, we’ve learned that RNA transcripts from one gene can be spliced in different ways to produce different prote…
Phillip A. Sharp: RNA Splicing: What is a Gene?
Phillip A. Sharp explains the seminal experiments he performed in the late 1970s that demonstrated the splicing of introns from newly transcribed RNA in human cells. Since those experiments, we’ve learned that RNA transcripts from one gene can be spliced in different ways to produce different prote…
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