# Jef Boeke
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Jef D. Boeke is an American geneticist who is currently the founding director of The Institute for Systems Genetics at NYU Langone Medical Center. From 1986 to 2014 he was on the faculty of The Johns Hopkins University School of Medicine, where he was the founding director of the High Throughput (HiT) Center. He is a member of the American Academy of Arts and Sciences as well as the National Academy of Sciences.Boeke received a Bachelor's degree summa cum laude in Biochemistry in 1976 from Bowdoin College.
Biocontainment safeguards
Jef Boeke explains how to safeguard against unauthorized growth of engineered microorganisms.
Synthetic Genomes, Climate Panel, Local Recycling. March 1, 2019, Part 1
DNA is the universal programming language for life, and the specific code to that program are the combination of the base pairs adenine, guanine, cytosine and thymine. But are those the only base pairs that could be used to create DNA? Scientists looking into this question were able to create 4 dif…
How to write a genome with Dr. Jef Boeke
Beer! Wine! Chocolate! Bread! Coffee?! You have yeast to thank for some of the best things in life and it hasn’t even gotten started. In this episode of Beer with a Scientist, Dr. Boeke will show us how it’s possible to literally write the future into this trusty little eukaryote’s DNA.
Jef Boeke …
Successful gene editing in yeast sheds light on chromosomal activity
Axios
Scientists from two teams reported Wednesday in Nature they were able to use CRISPR-Cas9 gene editing technology to dramatically restructure a yeast cell's complex genome that continued to live but was sometimes unable to reproduce in future generations.
Why it matters: Scientists seek a …
Covid vaccine boosters; why we don't have a tail; cassowary domestication; Royal Society Science book prize shortlist
Booster vaccines are now being offered to people in England most at risk of Covid, who had their second jab at least 6 months ago. Most people are getting an mRNA vaccine as a booster, mainly the Pfizer one. Dr Andrew Ustianowski, national clinical lead for the UK COVID Vaccine Research Programme,…
A Redesign for Yeast’s Genome, Chromosome by Chromosome - Jef Boeke, Weimin Zhang & Leslie Mitchell
To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked to replace yeast’s native chromosomes with synthetic versions. This project has turned out to be an international collaboration, with some ar…
31. Reimagining Genomes w/ Jef Boeke
In this episode, we’re joined by Prof. Jef Boeke, a pioneer in synthetic genomics. Jef shares his journey from uncovering retrotransposons in yeast to leading the ambitious Sc2.0 project, an international collaboration to design and build the world’s first fully synthetic Saccharomyces cerevisiae g…
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