Pioneering the Future of Cardiovascular Treatment with Sekar Kathiresan
In this episode of IDEA Collider, host Mike Rea speaks with Dr. Sekar Kathiresan, founder of Verve Therapeutics and now part of Eli Lilly, about one of the boldest ideas in modern medicine: using one-time gene editing to permanently lower cholesterol and prevent heart disease.
Dr. Kathiresan shares…
Revitalizing Pharma Collaborations: The Reblozyl Case Study
In this episode of IDEA Collider, hosts Mike and Rick revisit a pivotal project from over a decade ago, the Reblozyl project, undertaken in collaboration with Acceleron and Celgene. Rick, the head of Growth and Innovation at IDEA, reminisces about the early days leading to the successful positionin…
Rewriting the Future of Rare Disease: Engineered tRNA and a New Therapeutic Paradigm with Michelle Werner
In this episode of IDEA Collider, host Mike Rea sits down with Michelle Werner, CEO of Alltrna, to explore a groundbreaking approach that could transform how we treat thousands of genetic diseases.
Michelle shares how engineered transfer RNA (tRNA) technology has the potential to address nonsense…
A Single Injection set to Eliminate Cancer? CEO of Candel Therapeutics - Paul Peter Tak
What if a single injection could teach the immune system to eliminate cancer, and keep it away?
This week, in another episode of Leading Beyond the Lab, Lawrence Rose sits down with Paul Peter Tak, MD, PhD, FMedSci, President & CEO of Candel Therapeutics, one of the most quietly compelling stories …
AI & Competitive Intelligence in Pharma: Smarter Decision-Making with SAI MedPartners
In this episode of the IDEA Collider podcast, industry experts explore the evolving role of AI in Competitive Intelligence (CI) in pharmaceutical and biotech strategy — and how organizations can move beyond data collection to drive smarter, more confident decision-making.
Featuring insights from …
Building the Future of Targeted Protein Degradation Medicines with Nello Mainolfi
In this episode of IDEA Collider, host Mike Rea sits down with Nello Mainolfi, founder and CEO of Kymera Therapeutics. Nello shares his journey from medicinal chemist to biotech founder and discusses the opportunities and lessons learned from building a company at the forefront targeted protein deg…
Scaling CAR-T for Autoimmune Disease: Warner Biddle on Kyverna’s Breakthrough Strategy
In this episode of the IDEA Collider, host Mike Rea sits down with Warner Biddle, CEO of Kyverna Therapeutics, to explore how CAR-T cell therapy is expanding beyond oncology into autoimmune disease—and what it takes to scale one of the most complex innovations in modern medicine.
Warner shares…
Vir Biotechnology: Marianne De Backer on Immuno-Oncology, Hepatitis Delta, and Biotech Turnarounds
In this episode of the IDEA Collider, host Mike Rea sits down with Marianne De Backer, CEO of Vir Biotechnology, to explore how she is leading one of biotech’s most complex transformations.
After the rapid rise and decline of COVID-19 revenues tied to sotrovimab, Marianne stepped into Vir Bio in …
Scaling TCR-T Therapies: Reagan Jarvis on Non-Viral Gene Editing and Target Mapping
In this episode of the IDEA Collider, host Mike Rea sits down with Reagan Jarvis, scientific founder and CEO of Anocca, to explore how TCR-T cell therapy could unlock the next frontier in cancer treatment—particularly for solid tumors.
While CAR-T therapy has transformed outcomes in hematologic c…
RI Gov Candidates Release TV Ads, Campaign Season Ramps Up: Mike Raia Joins. Inside Communications presented by Half Street Group
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In this episode, Mike Rea, president and founder of Half Street Group, shares insightful analysis of the current Rhode Island political landscape, focusing on campaign strategies, media influence, and voter engagement. Whether you're a political enthusiast, a strategy professional,…
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