# Eric Klann
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eric klann is an American neuroscientist who studies how molecular signaling, synaptic plasticity, and behavior are altered in developmental disability, autism, aging, psychiatric disorders, and Alzheimer's disease.His research is focused on the molecular mechanisms underlying activity-dependent, long-lasting changes in neuronal function and the role these mechanisms play in complex behaviors, including cognition.
As a postdoctoral fellow in David Sweatt's laboratory at Baylor College of Medicine, Klann was the first to demonstrate that persistent protein kinase activity was associated with long-lasting synaptic plasticity.
After becoming an independent investigator, his laboratory was the first to show that at low concentrations, reactive oxygen species (ROS), which are typically considered to be neurotoxic, are in fact signaling molecules that are required for synaptic plasticity and long-term memory.
Translational Control in Neurons with Dr. Eric Klann
Creating new proteins is necessary for neurons to change the strength of their connections with each other. This process, known as translation, is controlled by a complex system of molecules and signlaing pathways. Anthony spoke with Dr. Eric Klann (Professor, New York University) about how underst…
Eric Klann speaks at Brain Awareness Day 2012
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Dr. Eric Klann, Professor of Neural Science at New York University, speaks about the molecular basis of autism spectrum disorders at …
Eric Klann speaks at Brain Awareness Day 2012 (Audio)
If you experience any technical difficulties with this video or would like to make an accessibility-related request, please send a message to digicomm@uchicago.edu.
Dr. Eric Klann, Professor of Neural Science at New York University, speaks about the molecular basis of autism spectrum disorders at …
Eric Klann: Activity-Dependent Protein Synthesis: Roles in Memory, and Neurological Disorders
The molecular machinery that translates the messenger RNAs into protein is located in ribosomes. Ribosomes are present within neurons in or near synapses, where they are particularly abundant in postsynaptic sites. Evidence suggests that local protein synthesis is required for the 'strengthening' (…
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