Transcrição completa de 882: Biohacking Your Mitochondria: How Carbon 60 Could Be the Ultimate Anti-Aging Antioxidant

safe? Have you removed some of the industrial elements and made it very like organic and more safe for the human system? That's a that's a great question. And and C60, right? The the chemical name is C60 or carbon 60, and the way we really think about it is that C 60 is for industrial applications, and there is peer-reviewed published research. If you proper improperly process it, it's harmful. ESS 60 is C 60 that's been processed for people and pets. Unknown Speaker 6:14 And when you think about, yes, it has the shape of benzene, but it doesn't have the same formula as benzene. So the scientific intuition just turned out to be wrong. Like they just thought, okay, this molecule is going to be toxic because there's that benzene shape, and that's never good. And then they throw it in this toxicity study, and instead of being toxic, the test subjects live 90% longer. I'm going to actually add to that. There's at one point my director of research came to me and said this particular research paper could have been five separate research papers because so much was covered in it, and one of the pieces is this, which is kind of amazing. So a typical Wistar rat will live out to 32 months and will have a known amount of tumor mass in its body. The longer it lives, the more tumor mass it gets in its body. Even though the MyBattle C rats lived out to 62 months, again 90% longer. None of them had any tumors, right? So they should have had twice as much. They had none, which is let's be realistic. That's probably a big reason that they lived so much longer. Now I tell that stories to some people, and they're like, "Oh, cure for cancer," and my immediate response is no. And then I like to add another no. Let's just be really clear. There's a big difference between dealing with a cancer that has metastasized and potentially being a cancer preventative. We actually know things as simple as good exercise, good nutrition, good sleep are cancer preventatives. That piece of the study just throws this molecule into that arena as a potential cancer preventative. Now, I do want to share one other study just because I think it's very relevant in this context. And the first thing I'm going to say about this study is it's a petri dish study, and this is the lowest level of biological study that you should ever. I would trust any testimonial over a petri dish study because the testimonial means they're still alive. Lots of stuff that happens in a petri dish doesn't do very well in living creatures, but in this petri dish, they had cancer cells and healthy cells, and they introduced an anti-cancer agent. And an anti-cancer agent is really a poison. You're trying to poison the cancer cells before the healthy cells. In the presence of the ESS60 molecule, there was increased efficacy against the cancer cells and protective effects for the healthy cells. So basically, with ESS60 present, more cancer cells died, less healthy cells Unknown Speaker 8:29 died. And and you might ask why is that? And our current theory is related to the Boss theory, which is fundamentally what we think this is doing in the mitochondria. And it is understood that, and it's actually defined as the Warburg effect. And in fact, Dr. Warburg won a Nobel Prize for coming to the understanding that cancer cells use energy very differently. Their mitochondria use energy very differently, and we don't know the specifics. But the fact that this ESS60 molecule is known to be in the mitochondria and what we think it's doing there is probably what's going on in in that context. So interesting. So so ESS 60 is thought to interact with free radicals. So is it acting directly as an antioxidant, or it boosts our own endogenous antioxidative systems, or how does it actually affect the mitochondria? Yeah. So I'm going to walk through because there's kind of I think the journey is always interesting, right? And and and so, in fact, I'm going to roll back because there's some fun stuff. In in 2012, this research paper comes out where the rats live 90% longer. In mid 2013, we started getting phone calls from this crazy wacky group of people called biohackers, and I can say that affectionately because I am I am now you're one of them. Yeah, Unknown Speaker 9:47 me too. Very affectionately, right? Unknown Speaker 9:50 And they were like, "Hey, that stuff in the rat study. How much of that stuff should we be taking?" And you have to imagine my business partner and I were carbon nanomaterial scientists, conservative carbon nano. Unknown Speaker 10:00 Material scientists, what we heard them asking was, "Hey, Chris, that stuff that you sell to research institutions around the world to put into inks, batteries, tires, and photocells, how much of that stuff should I be consuming on a daily basis?" And we actually thought the answer was zero. In we we added "not for human consumption" to our labeling in mid 2013. So think about that. From 1991 all the way to 2013, we don't have to have "not for human consumption" on the labeling. In 2013, we do add it now. And again, we knew it was safe in the literature, right? It was very clear not only safe, but these rats live 90% longer. So in other animal models, very safe. But we're conservative nanomaterial scientists, and this actually led to an interesting situation where we were getting two to three phone calls per week from this crazy, wacky group of people called biohackers, and those calls would sound something like this: A Joe would call, and Joe would say, "Hey, Chris, I got to share. My knee pain is gone," and I would say, "Joe, you mean the knee pain of your rat, right? Because it literally says not for human consumption on the labeling. And Joe would go, yeah, yeah, yeah. Hey, if my rat weighs 275 pounds and does HIT training on Wednesdays and Fridays, should I take? I mean, should my rat take more on Wednesdays and Fridays? And and again, so we knew the answer is yes, but but we knew what was going

on, and because it was clear in the literature that it was safe, we kept it going. But we still kept not for human consumption on our labeling. Every quarter, my business partner Robert and I would get together in the conference room, literally behind the room right behind this wall, Unknown Speaker 11:33 and decide: Do we want to get into this supplement space? Unknown Speaker 11:37 Part of me would say: I wish I was smarter and had done it sooner, but the other part is we're just conservative scientists, and honestly, you're in the space. It's is is it's generous to say that the supplement industry is challenged. It's a challenged industry, like maybe even very generous. In fact, I've had experiences in the last 30 days with people that I respect a lot that I'm like, yeah, this industry is very challenged, and so challenge is a good word. Unknown Speaker 12:05 Other words come to mind. Yeah, many other words, and some not appropriate even to any audience. Unknown Speaker 12:13 So every quarter we got together and like, no, we don't want to get into this industry. And in fact, in the time frame between 2013 and really this changed in 2018. I found a peer-reviewed published research paper that showed that 50% of the supplements that this research group had purchased off the market didn't have in them what they said they had in them. Right? This is a challenged market. That's why. Yeah, that's why we didn't want to get into it. And and some even have dangerous stuff in them. Like that's even scarier. Like okay, great. You say you have a you know whatever one gram of vitamin C, and you don't. Okay, but you have something else that's dangerous. That's even worse. So, all of that changed at the latter part of 2017. A guy with a big YouTube following, because that's how everything changes these days, started talking about all the benefits he was getting taking it on a daily basis, and our phone went from two to three calls per week to 10 calls a day. So at that quarterly meeting, we're like, okay, maybe we could have been smarter, and there was a bigger opportunity here. And then the other part of the conversation was we looked back at that peer-reviewed published research paper where 50% of the supplements on the market don't have in them what they say they have in them, and we're like, this is going to happen in this space. So we are the oldest and longest manufacturer of this molecule on the planet. We have the exacting standards. We've got the lab equipment. We've been delivering to the most stringent audience. That's scientists who can actually test what you ship them. Right, the average consumer cannot test what you ship them, and so we realized we needed to get into the industry. And really, our customers, you know, 10 calls a day were twisting our arm. And we asked ourselves two questions. The first question is a moral question: Are we comfortable selling it? So I take it. My wife takes it. Everybody on our team here takes it.

By the way, not a requirement. We don't. You don't clock in, and somebody makes sure you take my vital C. Really, everyone on our team has access to all the research, like anyone. But probably more importantly, they have access to the testimonials coming into because we handle customer service here. Those amazing testimonials that we actually really can't share. We're doing some research, and I'm sure we'll talk about the research that we're going to do relative to that, so that was the moral question. Yes, we're comfortable selling it. The next one is the legal. You got to cross with the FDA and the FTC. You got to cross the T's. You got to dot the I's. We're doing that, and so in 2018, we started bringing this to market. Now you asked a question. I went down a kind of fun rabbit hole. Now in 2018, my role as the chief scientist is to figure out what's going on here. Like, why are we getting these benefits? Why is Joe's rat's knee pain gone? Unknown Speaker 14:51 And the first place I hung my hat was the sleep. Again, if you can just improve sleep, you will improve mental, physical, and emotional well-being. Unknown Speaker 14:58 The next thing I. Unknown Speaker 15:00 Looked at is these rats live 90% longer. What does the medical community tend to think about aging? And they don't all agree, but they tend to think of it as an oxidation and an inflammation process. So, as an antioxidant, there's an ad hoc study on the web showing us to be 172 times more powerful than vitamin C. There's peer-reviewed, published research showing us to be 125 times more powerful than vitamin C. So I'm in Texas. We put a big old check mark next to antioxidant. The next is inflammation, and you probably know this. You have to be really careful when you're talking about inflammation, because the FDA equates conversations of inflammation with the diseases of inflammation, which are also the diseases of aging, so arthritis, Alzheimer's, cardiovascular disease, cancers. So if I come on your show and I say we address inflammation, what the FDA hears is me claiming we cure cancer, we cure cardiovascular disease. We are not making that claim. There is so much expensive research that needs to go into this product in order to be able to make that claim. What the FDA does allow us to say is that we address inflammation as it relates to exercise-induced inflammation, right? So we all had a tough workout, maybe just walked farther one day than normal and felt that sense of inflammation in our body. It does. The FDA allows us to say we address that type of inflammation, and then so that's a nice explanation, right? And we're kind of talking about this addressing this aging, but I like to roll up my sleeves even more and dig deeper. And here's where we've landed. It's called the Boss theory. It stands for Buffering Oxidative Stress System. And what gives credibility to this theory is there is peer-reviewed published research showing this ESS60 molecule inside of the mitochondria, and we also know from way back in the 90s that this molecule can hold on to up to six negatively charged particles on the exterior of the cage. So here, what's this? Here's what this looks like. Unknown Speaker 16:52 I'm I'm gonna I'll get a little geeky, and then I have a fun analogy. I think you you in the audience will appreciate it. But I'm about to get a little geeky and a little bit refresher here, right? So mitochondria, power source of every cell. There's between 50 and 5000 mitochondria in every cell in your body, except for your blood cells, which have zero, and your brain and neurons, which have 2 million. It is amazing how much energy our nervous system uses relative to our other systems. Like any power source, there is a negative byproduct. You think about your car going down the road. There's exhaust. You think about a power plant. There's a smokestack. In the case of mitochondria, it's reactive oxygen species. The way I picture these, they're like little bumper cars. If they're left to their own devices, they're running around the body, and everything they smack into, they rust. They cause oxidative stress and oxidative damage, and ultimately inflammaging, Unknown Speaker 17:45 and that's horrible. But like all so many biological systems in our bodies, there's a way to manage that internal to the mitochondria, and it's typically antioxidants like glutathione and melatonin that will manage those reactive oxygen species. Now, melatonin is the sleep hormone. Our most consistent testimonial involves sleep, so there's some nice parallels happening right here in the mitochondria. So in a healthy mitochondria, it's producing the energy for the cell. It's producing these reactive oxygen species, and that glutathione and melatonin is bonding to them, so they can't run around like little bumper cars. But what happens if you stress a mitochondria. Of course, this begs the question: How do you stress a mitochondria? I like to point out: If you're alive in modern society, you have stressed mitochondria. Right? Smoking, drinking smog, EMF radiation off of your cell phone device. If you're alive in modern society, you have stress mitochondria, and that's when it starts producing more reactive oxygen species than the internal glutathione and melatonin can manage, and that's when they're left to their own devices. They'll run around and cause all that damage, and that's where the ESS60 molecule comes in. Remember, peer-reviewed published research shows it's in the mitochondria. We believe it's holding on to up to six negatively charged particles on the exterior of this cage, so they can't run around like little bumper cars and do damage, and then when that mitochondria can replenish the glutathione, replenish the melatonin, then it can manage them appropriately. So that's my geekiness. I need your your rating. I didn't go through medical school. I don't. I I feel like all biological analogies should start with Mardi Gras.

Unknown Speaker 19:22 Okay, let's hear Unknown Speaker 19:24 it. So, so I mean, let's be realistic. A lot of biology happens at Mardi Gras, so why not? Unknown Speaker 19:29 So, it's the end of Mardi Gras, and you have these drunk reactive oxygen species on Bourbon Street running around, spray painting walls, smashing windows, all this horrible stuff, and you've got the New Orleans Police Department, the glutathione and the melatonin coming onto Bourbon Street, handcuffing themselves to those reactive oxygen species and getting them off of Bourbon Street. But what does the New Orleans Police Department do when they get overwhelmed? They take those reactive oxygen species and they stick them in a paddy wagon. They attach them to the exterior of the ESS60 model. Unknown Speaker 20:00 So they can't run around and do damage, and then when the New Orleans Police Department can replenish the glutathione, replenish the melatonin, then they can handcuff themselves to those reactive oxygen species and get them off of Bourbon Street, where they've never done the damage that they would have done. And that is why we say the ESS60 molecule Unknown Speaker 20:18 is the boss buffering oxidative stress system, and this whole summary is: we believe we're reducing the negative impact of stress mitochondria, and if you reduce the negative impact of stress mitochondria, you really should have systemic benefits, and you should have what we have, which are head-to-toe testimonials. I'm sorry that was very long. Interesting. I want to know why you chose New Orleans. We can't have California analogy. Unknown Speaker 20:42 That's great. I don't. What's another? I guess you could choose kind of any. Maybe Disneyland. Like, oh yeah, festival. You could do like Burning Man. I think Burning Man. Yeah, I biohacking Burning Man. Yeah, yeah. There's less arresting happening at Disney World. Unknown Speaker 20:57 So Burning Man then. Yeah, Burning Man. I like that. Unknown Speaker 21:01 That's very good. Well, how does C 60 work together with other antioxidants we may be already taking, like coenzyme Q, or as we said, like N-acetyl cysteine, glutathione? Is it Unknown Speaker 21:13 all going to join in? And what part of the electron chain is kind of impacted most here? Yeah. So when you start thinking about the mitochondria, there are a number of people out, kind of, kind of in the biohacking space who think of a trifecta of mitochondria support being the ESS60 molecule, red light therapy, and methylene blue. And my understanding is that each of those works in a different part of the electron transport chain. We see the ESS60 molecule downstream from the electron transport chain, right? So as these reactive oxygen species are coming out, as they're, I mean, the mitochondria is really fascinating, right? Because, I mean, for so many reasons, right? It's it's the the main producer of pregnolone, the the kind of precursor hormone for our sex hormones, which is a lot of people don't think about that in terms of mitochondria, but one of the things it's responsible for providing the energy to the cell, and as we're used to, when you provide energy, there's this negative byproduct. But the mitochondria is able to produce more energy than it can handle of the negative byproduct, right? So you can produce a lot more energy, and that ends up producing a lot more of these reactive oxygen species. Why is that? Well, it kind of makes perfect sense from an evolutionary standpoint because if I need energy to get away from the lion, I don't care how much damage I'm going to do tomorrow, next week, next month because of this oxidative stress and this you know inflammaging. I just need the energy today, so it's got this ability to exceed its capability of handling the the negative byproduct in order to produce more energy. So we really do see it as synergistic, not a replacement for these antioxidants. Unknown Speaker 22:57 But I will I will add. So so we really see it giving breathing room to the mitochondria so that it can do its job, right? So in that situation, you're running from a lion. You need the extra energy. It's producing more reactive oxygen species. It's just kind of bucket. It's kind of a bucket that holds. I've got another analogy. Unknown Speaker 23:18 I like to picture our physiology like a prairie with beautiful prairie grasses and prairie flowers, and stress is good for us. Let me kind of belabor this point a little bit. If you don't think stress is good for us, just look at astronauts when they come back from space. They are a health dumpster fire. Their bone density is reduced. Their immune system is compromised. Like stress is good for us, but it needs to be the right stress. So I think like a gentle rain on this prairie is the right stress. But what happens when you over stress? When you get this deep dark cloud of stress pouring into one spot in the prairie, you're going to create a mud puddle, right? You're going to do damage, and this is where I kind of picture this ESS60 molecule as a sponge between that deep dark cloud and that prairie, absorbing that stress. Now it's important to note this is not some infinite miracle molecule. If you don't manage that deep dark cloud of stress, this sponge will fill up. It'll start to pour on the prairie, and you'll continue to do damage. So you've got to manage that stress at some point. But when you manage that stress, now I kind of picture you can gently squeeze this sponge across the prairie, and you don't end up with that mud puddle. So it is giving the breathing room to your mitochondria to do its job, Unknown Speaker 24:33 and I hopefully that answered your question. Unknown Speaker 24:37 Yeah, I think so. So it's okay to take other supplements along with it, and and and I'll make one more very interesting point. And actually, this was made to me by a bodybuilder, Chris Gethin. He's a natural bodybuilder. He was

the editor of like Muscle magazine. So you know, we we all kind of have a stereotype about a big muscly guy. This guy was also incredibly intellectual. I'm very. Unknown Speaker 25:00 Proud to call him a friend now. Unknown Speaker 25:02 At the first Dave Asprey Biohacking conference, he came by his booth. He was speaking the next day, and he said, "Oh, Chris, I'm going to be talking about your product tomorrow." And I thought, "Oh, he's going to be talking about anti-inflammatories in general or antioxidants in general." And literally, that's the only talk at day we've been to four of them now. That's the only talk I've ever attended, Unknown Speaker 25:22 and the last five minutes was about my vital C, and the reason is because this ES60 molecule is a selective antioxidant, very similar to hydrogen. Hydrogen is a selective antioxidant. Why is this so important? Well, it's the we have these things like I mentioned, stress is good, and then us having a hormetic response to that stress is what's really valuable. How do we increase our VO two max? How do we increase our strength? How do we create calluses? Like this is a hormetic response to the stress, Unknown Speaker 25:53 and antioxidants will dampen that hormetic response, but selective oxidants will not. Right. So this ESS60 molecule doesn't dampen that response. So if you're a bodybuilder, you you really should be very careful about how you time your your your vitamin C, your vitamin D, your vitamin E. But with the ESS60 molecule, you don't have to worry about that because it's not going to dampen that chromatic response. Interesting. So do we currently have any studies in humans or any placebo-controlled human trials talking about mitochondrial function or longevity, biologic age, levels of antioxidation? So, we are currently the only group that's pushing forward research in this space, and I'll tell you. I mean, the short answer Unknown Speaker 26:41 is, like placebo-controlled. I don't know that anybody, including us, because of how expensive they are, you know, double-blind placebo-controlled. That's really, if we were to decide that we want to take this in the direction of a medication, that's really the studies that that would happen. It's it's a probably Unknown Speaker 26:58 a unfortunate outcome of how the kind of how the system is laid out, right? Unknown Speaker 27:03 And there is no intellectual property, so all the patents on this have long since expired. And so, if we were to come out with a medication tomorrow, there would be you know a whole bunch of Unknown Speaker 27:16 generics on the market on day one, right? Right, right. But here's what we're doing, and in fact, I'm going to map this out Unknown Speaker 27:23 in because people ask, what is what you know what is the experience on the molecule look like, and and so I'll break this down. Month three is really when we get into the research that we're pushing forward. Really excited about that. In fact, I'm going to start this with, we are a very very weird supplement company, Unknown Speaker 27:39 and what I mean by that is most supplement companies do not do research. Even fewer publish that research. So we did publish in 2024, 2025. We're hoping to get one paper in under the wire in 2026, and we are pushing forward some studies on humans. And here's what that looks like. I'll map it out this way. We think of the experience on our product as a three-month experience, and it has a lot of parallels with the most consistent testimonial of people taking the product in the morning, reporting mental focus and energy during the day, and then better sleep that night. So month one really is about focus and energy, and there's one testimonial that that just resonates here. So we got some product to an influencer, she took the product in the morning, sent in her video that night, and in that video, she pointed out that she didn't finish her cup of coffee. Now, if you're a coffee drinker, to notice that you didn't finish your cup of coffee is a big deal. I'll share. I used to be a two to three cup of coffee per day person. I'm now a half a cup, one cup. In fact, I still have some. It's 12 o'clock, so I probably shouldn't have much after this. Unknown Speaker 28:46 But for me, it's the routine, right? I come in, I make my cup of coffee. It smells great, it tastes great, and then I go about my day. Unknown Speaker 28:53 So I'm not drinking two to three. So that's focus and energy. Month two is really sleep. Now we do think deeper sleep is happening in month one. It's supporting that focus and energy. But I think why it takes into month two is because everybody gets a little bit more or less sleep every day, right? An hour extra here, an hour less there, whatever. And so it can be very hard to say, oh, I started taking my vital C, and collectively my sleep has gotten better. the The way my business coach puts it, he says, for 50 years he needed an alarm clock. When he started taking this product, he wakes up before the alarm clock. Now he's a business coach, so it doesn't matter if he has a late night mixer or a late night dinner. Unknown Speaker 29:33 He wakes up before the alarm clock. With one caveat, if he doesn't get the product for 10 days, then he starts to need the alarm clock to wake up, and that coincides with the literature that this molecule clears out of your system in about 10 days, and then finally in month three, when you think about reducing the negative impact of stress mitochondria, you should have systemic benefits. And we honestly have testimonials that we can't share. We have to do the research to share them. So we're starting four studies. Unknown Speaker 30:00 One of them has already been started. It's a frequent and severe headache study. Unknown Speaker 30:05 I am the geeky guy that you see in front of you. I have a spreadsheet. You mean like migraines, probably? Unknown Speaker 30:12 Yeah.

You can't say that, but I can say that. Yeah. Okay. Unknown Speaker 30:16 That's exactly what I said. Okay. Unknown Speaker 30:20 Yeah, I used to get frequent and severe headaches, the kinds that would stick you in a room, cold, dark, quiet room for a couple of hours to tolerate. And I would get four to five of these per year. And I was my spreadsheet was I'm the geeky guy trying to figure out what's going on. Maybe I drank too much. Maybe I exercised too much. I fought with my girth, whatever. Like because I just want these things to stop. When I started taking our product in 2018, I went 18 months without a single headache, and then I actually went off the product to join our sleep study, and I'll talk about that in a second because it was a crossover sleep study where you collect data on the product, data off the product, back on it. So I'd gone 18 months without a single one. I should have had six or seven by that time. I go off the product and I get my first one, and so that's why I'm not going to change my coffee routine because that's when I take my product and I don't want to forget to take my product. My wife, similar story. She used to get nine plus migraines a month when I finally. It's not easy to convince your spouse to do some stuff sometimes, so I finally convinced her to take the product. She went down to one or two a month, or even every other month. And then we have just other really powerful ones. So that's why we're doing that study. The next one is an hsCRP study. So that stands for high sensitivity C-reactive protein. It's an inflammatory marker typically associated with cardiovascular disease and cancers, Unknown Speaker 31:44 and we had a practitioner come to our booth at A4M. That's the American Academy of Anti-Aging. So big, big event in Vegas. We've been there last three years. We'll be there again this year in December. And he he came up and he said this, and then I was like, Dr. Young, I need to record this because this is so powerful. So I know what he said, right? He said, "Chris, I don't care if you're male, female, pre-surgery, post-surgery, cardiovascular disease, otherwise healthy. Your product is reducing elevated hsCRP numbers." And his example was nine down to point nine under one as normal ranges in four to eight weeks. Wow! Yeah, Unknown Speaker 32:20 and he said, additionally, they're seeing improvements in sleep and HRV between 20 and 60%. So we're doing this hsCRP study. There was a well, is a peer-reviewed published research paper that was studied published last year in Beagles that showed a reduction in hsCRP. So like we're really excited about that particular study. The next one is sleep. I mentioned me joining our own sleep study. We actually have completed two ad hoc sleep studies. There, there are small cohorts, but the most important piece of the study is 100% of participants reported improvements in sleep while they were taking the product. So, we're doing a more formalized version of that, so we can have data that we can publish, and then finally, we we actually have a cosmetic product. I you know you think about my business partner Robert and I getting together in the conference room once a quarter and saying we don't want to be in the supplement industry because it's a challenged industry. When one of our business partners came to us and said, "Hey, we should do a cosmetic. I was like, Yay! That sounds so amazing. Like that's why I woke up today. Unknown Speaker 33:26 We Unknown Speaker 33:27 bring this cosmetic, and at that time, my director of research comes to me and he said, "I found a peptide with 30 years of skin and hair improvement in peer-reviewed published research. I want you to look at it." So I looked at it and I'm like, "This is amazing. So we decided to bring. We call it UTH 29, which stands for Youth 29, the age we all want to stop aging at. Apparently, Unknown Speaker 33:50 that's funny. And the peptide is water soluble. Our ESS 60 molecule is oil soluble. We could have shoved these two together with an emulsifier, but emulsifiers don't sound healthy, and they're actually not. There's nothing good about emulsifiers, so you want to use as few as possible. And we decided to keep these separate. So basically, you do one squirt, one or two. I do two squirts of the UTH29 lotion, and then you do two drops per squirt. So four drops of the ESS60 activator. You activate it right there. Really, you're creating an emulsion right there in your hand. And because of the testimonials of that product, actually, because the peptide and the ESS60 molecule have research showing improvements in wrinkles and age spots in published research, we're doing a wrinkle and age spot study. Unknown Speaker 34:39 Okay, interesting. I think we should talk about that later. Unknown Speaker 34:43 We do a lot of those type of studies, but but I'm curious about what do we know about absorption, Unknown Speaker 34:51 metabolism, how it's eliminated, does it accumulate in Unknown Speaker 34:57 tissues? So I'll Unknown Speaker 34:58 share a typical survey. Unknown Speaker 35:00 Is one teaspoon, and it's a high-quality extra virgin olive oil with as much of the ESS60 molecule as we can get to dissolve in it. Because it's a high-quality extra virgin olive oil, it will leave a peppery flavor at the back of your throat. In fact, you know, every now and then, out of the blue, we get a call. Oh, it's burning my throat. Is it rancid? No, that's a sign of a high-quality extra virgin olive oil. In fact, you may have been to there's some chain Italian restaurants where they'll pour some oil in a little plate so that you can dip your bread in it, and they'll crack pepper into that oil. And the way they're cracking pepper is so that it tastes more expensive because the peppery flavor is a sign of an expensive olive oil. Unknown Speaker 35:40 In that one teaspoon, this is a pretty fantastic number. In one

drop of that olive oil, there are more than 400 times as many of these ESS60 molecules as you have cells in your body. Unknown Speaker 35:53 So one drop, 400 times as many of the ESS60 as you have cells in your body. That seems maybe that seems extreme, but if you think about going after the mitochondria, trying to saturate the mitochondria, you have between 50 and 5000 mitochondria in every cell, 2 million in your brain cells. Like that's probably the right number. Unknown Speaker 36:10 We do believe that there's an accumulation. The literature suggests this molecule, and testimonials suggest this molecule clears out of your system in about 10 days, Unknown Speaker 36:19 and so you've got some some some sort of ramp up, and at about 10 days, if you continue to take a dose, that's going to be continually cycling through your body, so that no accumulation is is believed to occur. Unknown Speaker 36:30 So, are people waiting 10 days in between doses, or you're taking it daily? So, I I wouldn't if you you know you know Avogadro's number right is the number that you need to calculate how many how many ESS 60 molecules are in a drop? Right, it's a huge number, but it still doesn't get you to saturation of all your mitochondria. Right, that actually happens right at about the at the four ounce point. Right, so that would be at the 30 days, but some stuff's falling off. Like there is a very good argument that the serving size should probably be a tablespoon, Unknown Speaker 37:04 but this molecule is pretty expensive to make. And just to share the way we make it, well, first before we share this, it is a naturally occurring molecule. So everybody in your audience has already been exposed to it. The the proof that I'll offer is, if you take the soot from a candle, so right, if you put a cold steel plate over a candle flame, you'll get that deep dark soot on that cold steel plate. That deep dark soot has parts per million or parts per billion of the ESS 60 molecule in it, right? So everybody's been exposed to it. But to make quantities that are appreciable that you might be able to put into a supplement, you actually have to vaporize graphite rods in an inert environment, so no oxygen, at a slight vacuum. What turns out, graphite is one of the hardest materials on the planet to vaporize. You need local temperatures of the sun to vaporize the graphite, and that's the beginning process of a very long, expensive process. So, really, the teaspoon we get amazing testimonials. But I'll share this. I had a conversation with Unknown Speaker 38:07 his name is Anthony Kunkel. He's a two-time U.S. Ultra Running Champion. He won a U.S. Championship at 50 miles and at 100 k. Unknown Speaker 38:17 And my first conversation with him was fascinating. He first said, "Hey, I was taking one serving of your formula, and I didn't really notice anything." And then I joke, like all good biohackers, he tripled the servings. Unknown Speaker 38:30 By the way, there are things that you should not triple for sure. And he said when he tripled the serving, he felt like the product could be the difference between somebody having running as a hobby or running as a career, and the way he Unknown Speaker 38:44 put it is that on the he said, "I don't believe that your product speeds exercise recovery. I believe it prevents damage in the first place." The reason he said it is because on the last five miles of a 50-mile run, which is a phrase you may never hear again, Unknown Speaker 39:01 where strength and stability were previously a problem, they're no longer a problem, and that does coincide coincide with that that prairie, right? Like if anybody's got that deep dark cloud of stress, it's Anthony Kunkel while he's running 50 miles, and if that protection is is being offered by the ESS 60 molecule, according to that boss theory, this all fits into place, and so I think the argument of you know tripling the servings is not an unreasonable argument. Unknown Speaker 39:28 Interesting. What Unknown Speaker 39:30 you did a toxicology study, I think, in 2024. When did that show? And are there any Unknown Speaker 39:36 questions remaining about like human safety exposure? Yeah. At this point there isn't right. You start with this initial toxicity study because they assumed it would be toxic, and the rats live 90% longer than the control group. And then there are a collection of tests. Like say, if we wanted to take our product into Whole Foods, they have a particular collection of tests that they want to see. Unknown Speaker 40:00 We have no interest in going to Whole Foods. In fact, we wholeheartedly believe if our product was sitting in Whole Foods, no one would buy it because nobody knows what ESS60 is yet. Right? Like we have so much more education that we need to do. Unknown Speaker 40:13 Even though we're not going to get into Whole Foods, we opted to do all the studies that Whole Foods would require because we believe that's a fair standard, right? Hey, all of these tests should be done if you want to get into Whole Foods. Whole Foods has a reasonable standard, so that's one of the studies that we published in 2024. I think the other one you might be looking if you look for Fathy Unknown Speaker 40:34 in order to save some money on getting that publication done. Dr. Fathy Musa published it on his own name. We would have had to pay a couple of grand in order to do that. But it is our study. We're the ones who funded that and coordinated with Dr. Fati Musa. By the way, Dr. Fati Musa is the original researcher. So when you think back to that study where the rats lived 90% longer than the control group, that was out of the University of Paris. It's often called the Bati study, B A A T Unknown Speaker 41:03 I, and that's because the grad student who did all the work was Bati, but the the kind of chief scientist behind the scenes was actually Dr. Fati Musa. So we

continue to have a relationship with him and continue to publish with him. Wonderful. How do you spell Fati Musa? Fati, F A T H I Moussa is M O U S S A. Okay, cool. I'm very nerdy. I like to read, so I'm gonna check it out. Unknown Speaker 41:31 I'll send you a PDF of all kind of the research associated with the molecule in general. So how it might whatever support joints, how it might support mitochondrial function. How it might support so many different things. So interesting. This has really ignited a lot of interest for me. I really feel mitochondrial aging is probably the most most important hallmark of aging. I think. Unknown Speaker 41:55 I think it's it's it's and and and really these are intertwined, right? The phrase inflamaging, right? Inflammation and aging, and mitochondrial health. Like I've done presentations on. Well, the fact that inflammation has a deleterious effect on mitochondria, and then your damaged mitochondria have a deleterious effect on your inflammation status. Like this is this is a it's a horrible aging spiral that that I think are intertwined. Yeah, are you doing other things that are important for your longevity? What else are you doing? I'm sure you exercise, but yes, yes. But what other supplements are you taking in terms of Unknown Speaker 42:32 what you think is scientifically beneficial? Yeah. Unknown Speaker 42:36 Well, so okay. So my focus is you've got to get. I'm gonna I'm gonna frame it this way. So I did do a longevity summit. I interviewed 57 experts in longevity, including like Dave Asprey, Ben Greenfield, Dr. Stephen Gundry, and I asked all of them for tips and tricks about longevity and a long health span. And then I kind of compiled the data. And this is pretty interesting because I'm kind of putting together the ideas of a presentation. And and they came out Unknown Speaker 43:03 the key things that everyone mentions, right? Like sleep, exercise, nutrition, mindset, and and community. Unknown Speaker 43:11 Sleep was at like 36, exercise and nutrition were both at 56, and then mindset was down. I don't know. We'll call it like 20% or something. And and when I first saw this data, I thought they got it wrong because sleep is so important, right? Like it's good for your mental, physical, and emotional well-being. And and you know, I obviously I have a little bit I have a proclivity for sleep because sleep my product you know testimonial is related to sleep, so I you know dive into sleep whenever I Unknown Speaker 43:40 can. And it's one of those things that I mulled over for a couple of days, and then I really did think they did get it wrong, Unknown Speaker 43:47 but not because of sleep, but because of mindset. Because if you need to change your sleep pattern, typically put the phone down, right? Not doom scroll in bed, and you don't have the mindset to do it, it's not going to happen. If you know you need to put the Twinkies down, and you don't have the mindset to do it. It's not going to happen. If you know you need to push your, I love the phrase, movement is life. Tough movement is freedom. Right? It's freedom from whatever aging is going to bring tomorrow. And you know you need to move yourself more tougher. I guess if you need more tough movement in your life and you have the mindset to do it, then you're not going to do it. And so that goes to mindset, and where I and I'll get to your question. But so so often people ask where should I start. That's where you should start, and you need to start on mindset. And I'll tell you, I actually do. You know, think about it. We have 2 million mitochondria in every brain cell. If we can support that, we're gonna be supporting your mindset. And I'll share one more testimonial and then get to your answer. I got some product to a lady in the UK. She sent her a video in, and the first part of her video, she said, "I'm in the middle of quitting smoking," and I was like, "This is a waste of money." I don't know if you, my parents used to smoke. They quit multiple times as growing up. It was never a pleasant experience. I mean, you're quitting an addiction. Unknown Speaker 45:00 And she went on to give a very good review about the product, and then she said something that I'll never forget, which is I find myself having a longer fuse with my toddler. Now I don't know if you've ever had a toddler, maybe that an adult who acts like a toddler, Unknown Speaker 45:17 and so to have a longer fuse goes to that mindset. The things that I focus on: exercise. I am. I love sprinting, and so I'm. How do I work on my VO2 max? I do resistance training. My belief is you should be sore two to three times per week. Now, Unknown Speaker 45:34 some people hear that and are like, "Oh, you need to be so sore you can't get off the toilet." No, you just need to know that you worked out yesterday. You need to be sore two to three times a week. You need to be working on flexibility, which I'm not doing a great job of. I actually did a good job this morning, and balance. Those are the kind of four movements. In terms of nutrition, I'll tell you, I had a DEXA scan 18 months apart. I added five pounds of lean muscle mass and dropped my percentage body fat by 2% in 18 months. I'm 57. Like that's not supposed to happen. And I can tell you, my workout it's changed since then. But my workout routine hadn't changed prior to you know the second DEXA scan. I ate more protein, and I ate significantly more protein. So my target, which I basically never hit, but my target, like to consume a lot of protein is one gram per pound of lean body mass, Unknown Speaker 46:25 and then I shove a lot of as many vegetables as my stomach can handle after that. And I know lots of people, well, not lots of people. There's a number of people would disagree with that. And then sleep, like like focus on that sleep. And then you asked about supplements. The key ones I'll take. I I will take a vitamin C. I

think vitamin C is is a is a very valuable supplement. Creatine. Basically, I do four grams in creatine in everything I drink all day long. So my target is about 15 to 20 grams of creatine a day. Wow! I think the research on muscle and brain health is pretty solid. Unknown Speaker 46:59 Is there anything else that I of course my product in the morning and then if I have tough days I'll take more at conferences I'm taking five or 10 teaspoons because Unknown Speaker 47:09 really an energy Unknown Speaker 47:11 demanding experience I'm trying to think is there anything else I recently started taking NAC I took a toxicity a Zoomer toxicity test had some mold but I live in Houston, so there was no surprise there. And Unknown Speaker 47:24 barium as a weird Unknown Speaker 47:27 heavy metal, so so I'm working on detoxing that NAC glycine, and then last part of the day, a little bit of activated charcoal. Wow. Okay, that's so interesting. I feel like we could go on and on. Unknown Speaker 47:43 Yeah, I think that ES ESS 60 fits really very well into this broad longevity landscape of like rapamycin, NAD, stem cell therapy, senolytics, all the things that we're doing with mitochondria. So, I think that this sounds like a really interesting molecule to introduce to our audience. I hope everybody really digs into the literature and understands if it's right for them. Maybe starts taking it. I can't wait to try it. So I'm excited to see Unknown Speaker 48:14 that and also your other products. So, Unknown Speaker 48:17 what's coming up next for you? Are you lecturing at another? You said A4M, A4M in December. Yeah, so we'll have a booth at A4M, and then we're going to the Biohacker World Expo in Miami. I'll be on a panel over there. Okay, so excited about we'll have a booth and I'll be on a panel. Unknown Speaker 48:36 Yeah, so those are the the key things between now and I don't know February. So interesting. I think I want to talk to you more about skin and fibroblasts and how this product maybe could be used for wound healing and and what we do in surgery and lasers and things like that, as well as hair follicle stimulation. I have so many ideas, but that's going to be another podcast. I hope we could do one more, like part two. That's that sounds awesome. I I did make a URL for your audience, and and I'd love to walk through like what people can find on that. Yeah, the URL is myvitalc.com forward slash dr k. So d r k a y. When they go there, I mentioned I interviewed 57 experts in longevity. I compiled 18 biohacking tips, and it's in a PDF, and they can get that for free. Just need your name and email. There is a coupon code. You can only find it there. There are deals on this page that you can't find anywhere else. And the first one, as you scroll down, as you'll see our four-ounce bottle and our Reduo set all together, and you can buy two, three, or six. And the reason we think about six, the best discount is of course on six, as high as a 40% discount on six. So that's pretty amazing. The reason we think about six is you can buy six, keep three for yourself because it's a three-month experience. Maybe give three to somebody else, or I paid for it, so I would have I would have kept the whole six. Unknown Speaker 49:59 The first. Unknown Speaker 50:00 First option is subscription, and then there's a little bit higher price if you don't go on subscription. As you scroll down, you could just get a two, three, or six of the. By the way, the subscription is the two bottles is every two months, three bottles every three months, six bottles every six months. Scroll down, similar offer for just the olive oil, and then just Unknown Speaker 50:19 the the Skin Reduo set. And then the other piece that I'm super proud of, as you go down that page, is my book Live Longer and Better. You can buy it at Amazon for 1995. At the bottom of your page, it's 19.95. For 10 extra dollars, I will autograph that book. The whole $10 fee goes to Operation Underground Railroad. You may remember an amazing movie called *The Sound of Freedom*. Amazing movie about a horrible topic, which is child exploitation. Operation Underground Railroad is doing a great job getting that off of our planet, which it should have never been here. So, 100% of that fee goes to Operation Underground Railroad. Ah, that's so amazing. Well, thank you so much, Chris, for coming on the podcast, and what's your social handle where people can reach out on Instagram or Unknown Speaker 51:06 in social media? Yeah, we we throw out a lot of stuff on the gram. My Vital C is the place you can find it. We're on TikTok. We're on YouTube. Unknown Speaker 51:16 Yeah, connected. We're constantly putting out some amazing longevity and health tips and tricks. I love it. That's it for now, guys. Don't forget to find me on my Instagram. It's beauty by Dr. Kay D R K A Y. Doing amazing things with people spaces and the beauty and longevity space. We are here to teach you all about the things you do to maintain your inner longevity and your outer beauty. That's it for now, guys. Stay beautiful. Transcribed by https://otter.ai