# John Maraganore
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john maraganore is an American scientist and life sciences industry leader.
== Education ==
John was born in Chicago, Illinois, U.S. in 1962 to Greek immigrant parents. In 1984, he completed his B.A. from University of Chicago in Division of Biological Sciences.
Episode 153 - September 5, 2025
On this week’s episode, hosts Paul Matteis, Sam Fazeli, John Maraganore, and Graig Suvannaveijh kick off the discussion with a more positive look at the sector and some of the fundamental factors at play. The group then shares an overview of Sanofi’s 10% stock fall on the back of positive Phase 3 e…
Episode 159 - October 17, 2025
On this week’s episode, Paul Matteis, John Maraganore, Eric Schmidt, and Graig Suvannavejh open with a look at biotech market sentiment, which has notably strengthened amid steady M&A and successful drug launches. The XBI is also up over 40% in six months, signaling optimism that the long “biotech …
What it Takes to Build a $50B Biotech Moonshot | John Maraganore, Founding CEO of Alnylam Therapeutics
In our latest episode, we sit down with Dr. John Maraganore, the legendary founding CEO of Alnylam Pharmaceuticals and one of the most influential voices in modern therapeutics. Raised in a Greek immigrant family in Chicago, John’s journey is a rare blend of scientific obsession, business acumen, a…
Episode 163 - November 14, 2025
On this week’s episode, John Maraganore, Yaron Werber, Ami Fadia, and special guests STAT’s Allison DeAngelis and Endpoints News’ Drew Armstrong kick things off with an overview of the latest FDA staffing changes, including long-time oncology chief Richard Pazdur’s appointment as the new CDER direc…
John Maraganore: The Importance of Being Unreasonable
Dr. John Maraganore, founding CEO of Alnylam Pharmaceuticals and co-founder of City Therapeutics, discusses his journey from a Greek immigrant household to pioneering RNA interference (RNAi) therapeutics. He highlights Alnylam’s growth from a startup to a major biotech company, leading to the first…
John Maraganore Reflects on the Long Game of RNAi and Drug Innovation
“I suspect that RNAi-based medicines will approach, rival, maybe even exceed what we’ve seen with monoclonal antibodies historically,” says John Maraganore, the CEO of JMM Innovations and founding CEO of Alnylam. He joins Bloomberg Intelligence’s senior pharmaceutical analyst Sam Fazeli to reflect …
Tim Harris: a Journey through 50 years of Biotechnology
Tim Harris is a molecular biologist, biochemist and geneticist. He is also a science and business leader with over 40 years of experience in a range of molecular research areas. Tim is currently an Operating Partner at SV Health Investors. Outside of SV, he holds a seat on the Board of Directors of…
Episode 5: John Maraganore has been a champion of innovation throughout his career. He discusses the road to success at Alnylam, today's environment, and keeping the U.S. on top
Reflecting on the decades-long journey at Alnylam, John Maraganore describes making it through lean times, and how far oligos and RNAi have come today. Matt asks him about championing true innovation, and what the word 'innovation' even means in today's environment. Plus, his thoughts on China, dru…
Episode 55: Alnylam
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From the discovery of RNA interference to the first FDA-approved gene-silencing therapy, this week on Petri Dish Perspectives, we dive into the story of Alnylam Pharmaceuticals, the company that turned one of biology’s most powerful mechanisms into an entirely new class of medicine…
Episode 189 - July 17, 2026
On today’s episode, Yaron Werber, John Maraganore, Sam Fazeli, and Matt Gline open with a discussion of biotech market volatility, with Matt noting that it often seems driven more by opaque factor dynamics than company-specific fundamentals. The group then turns to Eli Lilly’s continued “Amazonific…
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If I have seen further than others, it is by listening to podcasts and standing upon the shoulders of
giants.
‐ Isaac "Llamacorn" Newton
