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Welcome to the Gliden Longevity Podcast with Dr.
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Jeffrey Gladden, where our passion is helping you become an AJAX.
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On this show, we want to help you optimize your life energy, longevity, health, and human
performance with impactful and actionable information.
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By answering four questions, how good can we be?
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How do we make 100 the new 30?
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How do we live well beyond 120?
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And how do we live young for a lifetime?
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I'm Steve Ryder and Dr.
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Gladden.
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is February.
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Yeah.
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American heart month.
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Valentine's was just last weekend from the time that we're recording this.
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Any special plans with MOOC?
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yeah, we had a lovely time.
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Yeah, we, I've surprised her with a booking a hotel for Saturday night and a little
boutique hotel here in town.
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And, yeah.
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So we had, we had what we call a festival of joy where we just kind of hang out together
and yeah, just have a lot of really cool conversations, a lot of, sweet time together and
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that was good.
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yeah, super fun.
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How about you?
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I would just relaxed.
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made, I made some soup rather than go out.
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made some soup.
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is my girlfriend's favorite soups.
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Both of them one Friday night and one Saturday night.
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And that was our, Valentine's weekend.
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kind of relax and chill and hanging out with the boys and.
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Cool.
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Awesome.
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I love it.
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Yeah, no, all good.
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Yeah.
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So it's a birthday month for me too.
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I've got a birthday coming up a week from Friday.
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So that's cool.
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And my son and grandson are coming in town for the first grandfather, father, son weekend
together.
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He's six years old.
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So I'm really looking forward to kind of breaking the ice on the on the guys weekends kind
of scenario.
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So that'll be super fun.
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Nice.
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Nice.
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So American heart month and we have some articles and a paper.
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Let's start out with sweet taste receptors in the heart.
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A new pathway for cardiac regulation.
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Yeah.
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From what I, from what I gathered on this, it's, know, if you're drinking artificial
sweeteners, it can cause your heart to be a little irregular.
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Is that right?
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Well, not exactly.
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think what's interesting is we think that all heart rate response and strength of
contraction is controlled by, you know, either the nervous system, right?
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Putting more epinephrine down the sympathetic nervous system pathway to increase heart
rate and increase force of contraction or through hormones that are released from the
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adrenal glands, more adrenaline, you know, things epinephrine that do a similar kind of
thing, dopamine.
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What this is pointing out though, is that they found that when they gave an artificial
sweetener, spartamine, and I'm sure that it's probably true for sugar as well, that the
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heart actually responds directly to that molecule and increases heart rate and force of
contraction, which is interesting.
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So it's kind of like, you know, we've had this conversation before about, think that
eating is restorative, but it's actually has a stress component to it, right?
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Which is one of the reasons that
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Eating one meal a day has been associated with increased mortality, 80 % increased
mortality over eating three meals a day.
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And we know fasting is good, but we know that we've come to understand that eating is
actually stressful.
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So if you're eating sugar or sweets or even artificial sweeteners, it looks like you're
stimulating your heart to have an increased force of contraction and an increased heart
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rate.
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Right.
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So that can be a good thing.
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If you have underlying heart disease, right, like you've had bypass or a stent or you
haven't had those, but you've got a significant blockage or something like that.
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It's interesting to know that eating the sugar not only is destroying the glycocalyx in
your arteries, right?
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That keeps your arteries healthy and allows them to dilate appropriately and not develop
plaque and lower blood pressure, et cetera, improve sexual function, athletic performance,
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brain function.
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But it's also directly now.
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stimulating the heart and that's kind of new information that sugar would actually
directly stimulate the heart in terms of force of contraction and heart rate.
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So that's kind of cool.
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What would be your general recommendations about this?
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Well, you have an option, I would go for a run because your heart's ready to go.
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You know, I think if you're if your heart's healthy, it's just and you're and you're an
athlete.
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There was an interesting study that was done where if you took carbohydrate, let's just
say sugar and you didn't swallow it, you simply put it in your mouth and swished it around
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for, I don't know, 15 seconds or so and spit it out.
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And then rinse your mouth out with water.
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You actually had improved athletic performance just because the body perceived that it had
taken in carbohydrate.
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Yeah, that's crazy.
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Isn't that wild?
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So you didn't actually give your body more fuel.
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just sort of tricked it to thinking it got more fuel.
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And because of that, everything got better.
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So it just goes to show you in that case that the nervous system really is kind of.
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keeping the lid on everything, right?
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It won't let you, if it thinks you're overstressing your muscles, too much exercise, too
much oxidative stress, it'll shut things down.
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If it feels like you're depleting your nutrient resources, it shuts things down.
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If it thinks the force on the muscle in the bone is too great, right?
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It might break the bone or whatever, it shuts things down, right?
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So it won't really allow you to lift a weight that's.
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You know, heavy enough to kind of break a bone unless you've got really fragile bones.
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But anyway, the point is, you've got sort of the central nervous system control, over what
it allows your body to do.
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And when you proceed, when your central nervous system perceives that you've just gotten
carbohydrate says, okay.
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We're good to go.
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So it loosens things up and enables you to kind of, you know, run another three miles or
whatever.
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Right.
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So that's kind of, kind of interesting.
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So I remember when I got, when I tried out levels, the continuous glucose monitor, a post
meal walk or hike really helped to blunt that glucose response.
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And so I would assume you factor in the benefit of blood, of bringing that response down,
but the benefit of, you know, the, the increased cardio output, would that be
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Yeah.
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Something that you would recommend even more.
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There's a couple of things going on there.
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We know that after a meal, particularly after dinner, society has us still sort of
believing that dinner should be a big meal, right?
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Where we know from a health perspective, it probably shouldn't be a big meal.
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It should be something.
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Could be something.
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But the bigger meal should be lunch or even a mix between breakfast and lunch.
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But if you go out for that walk afterwards, number one, when you're exercising, you tend
to slow
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Food digestion and absorption, right?
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So that's one thing.
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The second thing is you're also sort of burning off some calories at the same time So you
kind of get kind of get a benefit for both and to your point since your body now Feels
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like it's replete with calories You know, it's kind of ready to go and your heart's kind
of ready to go anyway, so it's you just have to understand that if you have heart disease
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You're pushing blood into your gut
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to digest the food, which is one form of exercise for the heart.
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And then you're pushing blood to your muscles to be able to get you to exercise, which is
another form.
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So you're kind of doubling up on the exercise.
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So even though you're just going for a walk, you're kind of getting a more potent form of
exercise that way, which if you have heart disease could be too much, but if you're
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healthy, could be a really great way to go about it.
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So yeah, we like going for a walk after eating in the evening.
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So we have two articles about Takotsubo.
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Is how pronounce it?
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Yeah, it's Hakusubo.
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Takasubo syndrome.
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Broken heart.
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Talk about that because it looks like it's on the rise.
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Yeah.
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well, it's probably on the rise, for a couple of different reasons, but also, since it was
first described back in the nineties in Japan, it's now become more universally
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recognized.
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And I think a lot of it was not recognized previously.
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Right.
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So it's hard to know if it's an incidence in occurrence or an incidence in observation of
it.
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Right.
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Yeah.
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appreciation of it.
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So,
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But yeah, Takasubo is interesting.
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I saw a number of cases when I was, you know, doing interventional cardiology work and
basically boils down to what's referred to as broken heart syndrome, where the heart is
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exposed to stress and it could be psychological stress.
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Could be physical stress, could be a combination of the two.
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It seems to affect women about 90 % of the time, 10 % of the time in men, can occur in men
and it's sense to happen in women that are post-menopausal.
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And so my hypothesis is that the female heart is not structurally quite as strong as a
man's heart.
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Just, you know, just like their bicep isn't structurally quite as strong as a man's bicep.
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The sex is just kind of a hormonal effect, if you will.
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And then when women are post-menopausal and depleted of hormones, they lose muscle mass.
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Men do the same thing, but they have a little more to start with.
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And the heart becomes a little more vulnerable to the effects of high stress.
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So the high stress, you know, it's it's it's typically characterized as a psychological
stress, like, you know, the loss of a loved one or, you know, a tsunami hits a village or,
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you know, something that's, you know, heartbreaking, if you will.
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And all of the release of catecholamines into the system, the epinephrine, the dopamine,
norepinephrine, all that dumps in and it overwhelms the heart in terms of
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what it's asking the heart to do, right?
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Speeding it up, forcing it to contract more vigorously, things like that in response to
all those stress hormones and the nervous system as well.
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And the heart just kind of shuts down, right?
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And so what happens is it kind of balloons out and instead of going from pumping out about
60 % of the blood with each beat that it's been filled up with, it doesn't pump out every
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last drop, but pumps out about 55, 60, 65 % of the blood.
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It may drop down to pumping out 15%.
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Right.
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Yeah.
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What does that cause?
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heart failure causes heart failure where you're not pumping enough blood and the blood
backs up into your lungs and people get pulmonary edema and they can die from that.
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it's like acute heart failure.
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It's also associated, depending times, with chest pain.
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So there's kind of a pain response to it as well, kind of like a heart attack.
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it many times is diagnosed, somebody comes in with acute heart attack symptoms, but they
don't show
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some of the classic findings of heart attack on the EKG.
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It's different kind of EKG and I'm not going to the EKG details because we don't have
pictures to show people, but it can be determined that it's not an acute heart attack.
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And when you take them to the cath lab, you see that the arteries are typically clear.
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There's no clot, there's no plaque, but the heart muscle itself is very weak and it
balloons out.
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If you can imagine the body of an octopus, how it's kind of that big body now it has all
the eight
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legs coming off, tentacles coming off.
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The heart kind of looks like that.
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It just looks like it's ballooned out and hardly contracts.
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So that's how it got to name Takasubo.
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It can also happen with physical stress and it can also happen with, let's say you're an
inpatient and you just had your gallbladder out or you just had a major surgery and you're
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under a lot of physical stress as well as emotional stress.
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can occur in that setting as well.
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So yeah, Takasubo, it's an interesting thing.
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really only accounts for probably two, three, four, five percent of people that are seen
in an emergency room, probably more around two percent.
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Again, women more than men.
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yeah.
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Interesting.
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What's the treatment?
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the treatment, it tends to get better.
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Reduced.
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Yeah.
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In our world, reducing stress.
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When a heart is strong enough doing low dose beta blockade to block the beta receptors
that this is where the epinephrine, norepinephrine things are reacting, alpha and beta
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blockers like Corag, Corvetilol, kind of rest the heart, kind of remove that.
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stimulus from the heart, it allows it to regain strength.
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And then you can do regenerative things here too, right?
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This is a place where some of the regenerative factors, whether it's stem cells or
placental derived trophic factors and cord blood factors and things like that can all be
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beneficial.
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And then improving hormone levels can be helpful.
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You know, where you do get testosterone and estrogen back.
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which makes all the tissues more sturdy, you will, enables them to manage that stress.
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So there's two things here.
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One to try to prevent it.
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One, I would do hormone replacement therapy so that you're, you know, you don't lose the
muscle mass, both not only in your arms and your legs, but in your heart.
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the second is monitoring how your body manages stress.
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And we're really big, have become big fans of brain tap, which is a device that's a visor
and headphones that
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you know, uses binaural beats and photobiomodulation through the eyes and the ears to
actually entrain your brain into a particular waveform like alpha for meditation or theta
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for deep meditation or delta for sleep.
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And you can actually train your nervous system to receive a stressful quote unquote
stressful input and yet have more equanimity around it, not be as impacted by it.
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There's also some interesting cognitive insights about that too.
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in terms of how to manage stress.
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So one of them is, many times the reason we feel stress is because we are identified or
associated or attached to a particular outcome.
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Right.
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And if we, if we don't, if we unattach ourselves from the outcome, right.
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This is kind of a perspective shift.
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Yes.
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You see, then all of a sudden, stress can be decreased dramatically, particularly when our
identity is caught up in it.
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Like, I, know, I'm here to do this job and you know, I didn't get something done on time
or whatever.
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now it's like, there's a threat to me, my own identity.
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I'm attached to that outcome.
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Right.
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Yeah.
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And so.
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A lot of stress comes from that and the inside of realizing that, I will actually be a
free individual if I, it's, it's not a question of not caring.
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It's not a question of not connecting.
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It's not even a question of not loving or participating or really trying hard.
218
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It's just not identifying with the outcome and attaching our identity and our self-worth
and everything else to that outcome.
219
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Right.
220
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That's really important to learn to separate that.
221
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Right.
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And then that will really help.
223
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manage stress dramatically,
224
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It's massive.
225
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It's massive.
226
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Once I started to do that, I noticed my overall stress levels significantly decrease.
227
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Hey, whatever happens, happens.
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Yeah.
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And it's not even, yeah, I mean, it can be that, and it doesn't mean you don't even care
about the outcome.
230
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Like you want a good thing to happen, but if it doesn't happen, it's like, but it's not,
it's not me.
231
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It's like, well, what can I do to be helpful here?
232
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Right.
233
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And so you get away from that being caught up with your identity tied to it.
234
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I once heard this speaker in the Christian communities give this thought, and it's never
ask the why question because it'll never be answered.
235
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Instead, ask, what does this mean and what must I do?
236
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And changing that kind of perspective can be massive.
237
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Yeah.
238
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Yeah, that's right.
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What I find is that when you are not attached to an outcome, right, like in this podcast,
for example, I'm not attached to an outcome as much as I love this podcast and I love
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having these conversations and I care about the audience, right.
241
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But I'm not attached to the outcome.
242
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My identity is not attached to the outcome.
243
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Yeah.
244
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And what that does is it frees me up psychically to do the podcast and not be fatigued or
tired at the end of it.
245
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Right.
246
00:17:34,554 --> 00:17:42,836
Or it also frees me up to be more, either both thoughtful or creative in my responses, my
thoughts.
247
00:17:42,836 --> 00:17:47,478
So it actually it's, you know, we talk about freedom all the time, right?
248
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We talk about freedom and yet everybody signs up for indentured servitude, right?
249
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They tie themselves to a job and a salary and a, and, and for me to be a good person, I've
got to do this and perform at that.
250
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You see what I'm saying?
251
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We all sign ourselves up for indentured servitude.
252
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And yet we can free ourselves from all that.
253
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And this is how you do it, is by unattaching.
254
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And that decreases stress and that will protect you from Takasubo.
255
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So that's my take on Takasubo.
256
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Dr.
257
00:18:17,867 --> 00:18:20,570
Gladden dropping truth bombs.
258
00:18:20,711 --> 00:18:27,500
Next article we've got, if you can do this many pushups, your heart is healthier than you
think.
259
00:18:27,500 --> 00:18:27,870
Dr.
260
00:18:27,870 --> 00:18:30,283
Gladden, truth or myth?
261
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What do you do to improve your heart health?
262
00:18:35,554 --> 00:18:38,835
Well, there are many, many, many, many metrics like this, right?
263
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You could say the longer you can hold a plank, the longer you can hang from a bar, the
more pull-ups you can do, the higher your VO2 max, really the stronger your hand grip
264
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strength is, right?
265
00:18:50,220 --> 00:18:59,784
So all of these things are really similar measures, if you will, of just total overall
body fitness.
266
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And I think
267
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What we're saying here is something obvious.
268
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If you're fit, you do better, right?
269
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You have more physiologic reserve.
270
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So you have the ability to be more anti-fragile, which is a really important concept,
right?
271
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So fragility, of course, is when something unexpected happens, we're damaged by it.
272
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Strength is, resilience is the ability to actually absorb that and recover from it.
273
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And then basically being
274
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really sturdy, so to speak, or strong means that you're not even impacted in the first
place, right?
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anyway, I think when we think about the body and being in shape, you just want to be in
the best shape that you can.
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And I will tell you that some insights I've had are that you never can get in shape in a
gym.
277
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And you can never get in shape without a What I mean by that is that when you train,
you're not training your muscles.
278
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Everybody goes to the gym because they're going to train today.
279
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It's upper body today.
280
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It's legs today.
281
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It's this actually being fit.
282
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or whatever.
283
00:20:18,946 --> 00:20:30,095
Being fit is actually having a nervous system that is fast and responsive and agile and
quick and balanced and all those kinds of things and powerful and strong, right?
284
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And to generate all that force.
285
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And so you're really, if you focus on the fact that you're training your nervous system,
you'll realize that you can't sit on a machine or do a limited range of motion something
286
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and really train the nervous system to be fast, agile, strong, quick and balanced, right?
287
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It's not gonna happen.
288
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Even if you're doing
289
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you curls on one leg.
290
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You have to put yourself in an environment that's unpredictable.
291
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And the only way you get that is to get outside.
292
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You've got the wind, you've got the rain, you've got the boulder in front of you.
293
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You've got the tree that fell down in front of you, whatever it is, you've got to have
your skiing, your walking, your hiking, your running, whatever, biking, whatever it is,
294
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you got to have unpredictability to train your nervous system to be adaptable to these
things.
295
00:21:13,787 --> 00:21:17,309
And I think that's why you can never really get in shape in a gym.
296
00:21:18,336 --> 00:21:27,579
And I think you also need a gym because you do need to sit there and do some, some squats
and you do some leg presses and some other stuff to actually build up just pure strength,
297
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if you will, which is also a nervous system situation.
298
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But when you carry that strength into the unexpected environment of the outdoors, now you
have the fun of like, yeah, I'm strong.
299
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I can pedal up this hill.
300
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Right.
301
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But now I've got to dodge that and hop this and whatever else.
302
00:21:42,463 --> 00:21:44,520
So anyway, that's how I think about it.
303
00:21:44,520 --> 00:21:53,472
What's your normal ratio of strength training outside all of that and how has it evolved
over the last number of years?
304
00:21:53,484 --> 00:22:05,961
Yeah, well, it's a function of the weather to some extent, and it's a function of the
status of my body.
305
00:22:06,521 --> 00:22:10,984
So if I'm injured, it's a little harder for me to do certain things outside.
306
00:22:10,984 --> 00:22:18,468
So I'm a little bit more confined to a gym, but even in a gym, I'll try to make it
unpredictable and I'll get outside as soon as I can.
307
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If I have access to the outside,
308
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I will be outside probably five days a week and I'll be in a gym two days a week would be
about the right ratio.
309
00:22:30,814 --> 00:22:39,654
When the weather's bad or it's cold or this or, know, and it's, I can't get out and run
for either a scheduling reason or something, you know, in reality, it probably works out
310
00:22:39,654 --> 00:22:47,214
to where I get outside three days a week and I'm inside four days a week, but I'm still
outside as much as I can be.
311
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Yeah.
312
00:22:53,189 --> 00:22:57,030
GLP-1s are being used to treat heart disease.
313
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I can assume you have some thoughts about this.
314
00:23:00,098 --> 00:23:00,538
Yeah.
315
00:23:00,538 --> 00:23:12,083
Well, I JLP ones were basically, mimic, you know, the hormones that are secreted when we
eat that, you know, basically indicate that we're full.
316
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And so they decrease appetite.
317
00:23:13,884 --> 00:23:19,896
They, and so they've been used for controlling blood sugars in the sense of decreasing
appetite.
318
00:23:19,896 --> 00:23:28,220
Also, they do seem to improve insulin sensitivity and improve beta cell function and
things like that.
319
00:23:28,220 --> 00:23:29,068
And so.
320
00:23:29,068 --> 00:23:32,600
You know, they really were developed for diabetes.
321
00:23:33,521 --> 00:23:37,584
but then it was found that, people are actually losing weight on these drugs.
322
00:23:37,584 --> 00:23:39,525
So then it became weight loss.
323
00:23:40,286 --> 00:23:48,441
At the same time, people were realizing that when diabetics would take JLP once they had a
lower incidence of heart attacks, right.
324
00:23:48,441 --> 00:23:49,372
And strokes.
325
00:23:49,372 --> 00:23:52,694
And so there was been a cardiovascular benefit, right?
326
00:23:52,694 --> 00:23:57,897
There's an impact on lipid levels and, and, the way the heart responds to certain
stresses.
327
00:23:58,218 --> 00:23:59,078
So.
328
00:23:59,886 --> 00:24:06,849
It's really important to know that you're kind of enhancing a normal function in the body.
329
00:24:06,849 --> 00:24:10,431
The problem is that it's like anything.
330
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If you push it too hard, you start to get the negative effects.
331
00:24:13,122 --> 00:24:24,527
And so we see people that are, have become reliant on GLP-1s and GL1s to basically, you
know, lose weight.
332
00:24:24,527 --> 00:24:27,948
And what we find many times, because we measure everybody's
333
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body composition is that they're losing muscle instead of fat and they can be losing bone
density.
334
00:24:34,151 --> 00:24:36,553
Now there are papers published on this as well.
335
00:24:36,553 --> 00:24:50,184
So while it's useful, particularly for diabetics and for decreasing cardiovascular events
in diabetics and even in non-diabetics, and it's also good for preserving kidney function,
336
00:24:51,786 --> 00:24:55,549
they have to be used cautiously at the same time.
337
00:24:55,829 --> 00:24:56,970
And so
338
00:24:57,634 --> 00:25:02,378
We're fans of, of going about it a little bit differently.
339
00:25:02,378 --> 00:25:12,086
We'll use GLP once to kind of jumpstart a situation if somebody wants to lose weight, but
we actually think that a five day fast mimicking diet is really a great jumpstart.
340
00:25:14,129 --> 00:25:18,152
it resets the gut, bio resets or taste buds resets or appetite.
341
00:25:19,093 --> 00:25:21,465
and then from there you can use Mimeo.
342
00:25:21,465 --> 00:25:23,467
We've had a podcast on Mimeo, right?
343
00:25:23,467 --> 00:25:24,768
Which basically.
344
00:25:24,972 --> 00:25:29,544
has PEA and OEA and spermidine in it, a little bit of niacin.
345
00:25:29,645 --> 00:25:35,387
And the PEA and OEA, the OEA in particular, decreases appetite.
346
00:25:35,408 --> 00:25:44,873
So if you take three or four of those, now you're getting the benefits of appetite
suppression without loss of bone density or muscle mass.
347
00:25:45,593 --> 00:25:54,738
And you're getting spermidine, which is increasing basically autophagy in your cells and
you're increasing reverse cholesterol transport.
348
00:25:55,072 --> 00:25:58,965
So that's like a magical formula for keeping your arteries healthy.
349
00:25:58,965 --> 00:26:01,566
So we're big fans of that.
350
00:26:02,388 --> 00:26:10,293
And then there are also probiotics out there now that have GLP, that increased GLP-1
activity.
351
00:26:10,994 --> 00:26:15,037
And acromansia is one that is good for improving blood sugar control.
352
00:26:15,037 --> 00:26:21,982
So my point is if you're on a GLP-1 and you're listening to this, there are ways to get
you off of it.
353
00:26:22,164 --> 00:26:27,917
not lose ground and actually gain ground in terms of muscle mass, bone density and where
you really want to be.
354
00:26:29,419 --> 00:26:32,981
I think it's super important for people not to focus on the number on a scale.
355
00:26:32,981 --> 00:26:34,702
It's really body composition you want.
356
00:26:34,702 --> 00:26:39,385
And if you're serious about your health, get a scale that has a body composition component
to it.
357
00:26:39,385 --> 00:26:43,268
I think withings has one of those, I in body makes a scale.
358
00:26:43,268 --> 00:26:44,559
I think there's different ones out there.
359
00:26:44,559 --> 00:26:45,969
You can resource.
360
00:26:46,310 --> 00:26:46,894
but if you
361
00:26:46,894 --> 00:26:47,846
How accurate are those?
362
00:26:47,846 --> 00:26:49,719
Obviously it's not as...
363
00:26:49,721 --> 00:26:50,974
How accurate are those?
364
00:26:50,974 --> 00:26:51,946
Obviously it's not as...
365
00:26:51,946 --> 00:26:52,806
really matter.
366
00:26:52,806 --> 00:26:54,886
It doesn't really matter in a sense.
367
00:26:55,066 --> 00:26:56,206
It matters.
368
00:26:56,206 --> 00:26:57,826
Well, my point is it matters.
369
00:26:57,826 --> 00:27:00,446
They're not as accurate as the DEXA scan, right?
370
00:27:00,446 --> 00:27:06,666
But they're accurate enough that you can see changes in a positive direction.
371
00:27:06,666 --> 00:27:09,206
if muscle mass is going up, muscle mass is going up.
372
00:27:09,206 --> 00:27:12,586
If fat, percent body fat's going down, percent body fat's going down.
373
00:27:12,586 --> 00:27:16,226
It doesn't matter if it's 18 % or 22 % even.
374
00:27:16,226 --> 00:27:18,846
It's the fact that it's moving in the right direction.
375
00:27:19,286 --> 00:27:21,598
So yes, you want to try to get one that's been
376
00:27:21,598 --> 00:27:23,782
know, verified and accurate.
377
00:27:24,486 --> 00:27:27,113
But the point is it's really the change that you're looking for.
378
00:27:27,113 --> 00:27:27,784
So, yeah.
379
00:29:20,267 --> 00:29:30,028
Well, you mentioned artery health and our last article is dietary salt substitutes to
prevent heart attack, stroke and death.
380
00:29:30,028 --> 00:29:38,288
Basically it's talking about using potassium rich salt as a salt alternative.
381
00:29:38,288 --> 00:29:38,578
Dr.
382
00:29:38,578 --> 00:29:39,860
Gladden, what are your thoughts?
383
00:29:39,860 --> 00:29:41,281
I'd never heard of this.
384
00:29:41,281 --> 00:29:48,264
Yeah, well, it turns out that, yeah, there's some really interesting things around salt,
right?
385
00:29:48,264 --> 00:29:51,305
So we all grew up with, you know, Morton salt, iodide salt, right?
386
00:29:51,305 --> 00:29:59,029
And then we got away from that because everybody got infatuated with sea salt and Celtic
salt and things like that, which is great because it is many salts.
387
00:29:59,029 --> 00:30:00,269
It's not just sodium chloride.
388
00:30:00,269 --> 00:30:02,190
It's actually many different minerals.
389
00:30:02,250 --> 00:30:09,227
And having all those minerals is actually really good because a lot of the time in our
pasteurized world, we don't get all those minerals.
390
00:30:09,227 --> 00:30:11,999
So using those kinds of salts are helpful.
391
00:30:12,220 --> 00:30:19,245
What's also known though, is that potassium rich foods help lower blood pressure and raise
potassium.
392
00:30:19,346 --> 00:30:28,213
And likewise, if you put some potassium chloride into your sodium chloride, or even some
potassium chloride into your Celtic sea salt, to where you're getting some potassium, some
393
00:30:28,213 --> 00:30:37,480
extra potassium, that's been shown to actually relax tension in the arteries and lower
blood pressure, improve heart function and...
394
00:30:37,801 --> 00:30:39,202
improve arterial function.
395
00:30:39,202 --> 00:30:48,970
So you can get potassium from, you know, things like potatoes, or they're higher in
potassium than bananas, for example, sweet potatoes and white potatoes.
396
00:30:48,970 --> 00:30:55,316
And if you want to refrigerate a baked potato overnight and turn it into a resistant
starch, you don't get all the carbs from it.
397
00:30:55,316 --> 00:30:59,539
You get resistant starch that feeds your gut biome and you're still getting the potassium.
398
00:30:59,539 --> 00:31:02,322
So there are many ways to boost potassium.
399
00:31:02,322 --> 00:31:05,594
You don't have that necessarily get a salt substitute to boost potassium.
400
00:31:05,594 --> 00:31:06,835
You do it with food.
401
00:31:06,945 --> 00:31:12,227
But the idea of having more potassium is a smart idea for hard function.
402
00:31:12,227 --> 00:31:17,309
We know that too much sodium pushes us into higher blood pressure and things like that.
403
00:31:17,309 --> 00:31:29,073
So it's not that salt is bad, especially if you're getting all the minerals from like a
Celtic sea salt or something, but too much pure sodium chloride is not what you're after.
404
00:31:30,817 --> 00:31:31,098
Dr.
405
00:31:31,098 --> 00:31:34,486
Gladden, February, what's the latest?
406
00:31:34,486 --> 00:31:35,037
What's new?
407
00:31:35,037 --> 00:31:37,653
What are you excited for in the next month?
408
00:31:38,253 --> 00:31:46,133
Um, well, we're, we're basically, um, starting a new brain optimization program here.
409
00:31:46,233 --> 00:31:48,133
So we're super excited about that.
410
00:31:48,133 --> 00:31:54,933
We're, coupling many of the technologies that we have here, both diagnostically and
therapeutically.
411
00:31:55,053 --> 00:32:03,253
And we've always used a Dale Bredesen's protocol here in terms of, you know, fixing the 36
holes in the roof that are associated with dementia.
412
00:32:03,253 --> 00:32:04,153
Yeah.
413
00:32:04,153 --> 00:32:05,697
And so.
414
00:32:05,697 --> 00:32:14,304
We've been all over that, but now we have a number of things that actually are very
additive to that in terms of regenerative therapies, trans-cranial magnetic stimulation
415
00:32:14,304 --> 00:32:25,264
and peptides and no tropics and regenerative technologies like placental derived exosomes
and stem cells and things like that.
416
00:32:25,264 --> 00:32:26,405
So you put all that together.
417
00:32:26,405 --> 00:32:32,900
It's pretty magical plasma freezes to kind of clear out the trash and the inflammation.
418
00:32:33,000 --> 00:32:34,273
And then we have.
419
00:32:34,273 --> 00:32:39,054
genetic testing to actually understand who's at risk for what kind of dementia, things
like that.
420
00:32:39,234 --> 00:32:49,717
And now we're just getting a hold of a new product called TB006, which is a monoclonal
antibody that binds a molecule called galectin 3.
421
00:32:49,717 --> 00:32:56,459
And galectin 3 is a major player in enhancing inflammation in the brain.
422
00:32:57,140 --> 00:33:02,901
It basically turns on the microglia in the brain, which are the immune cells in the brain.
423
00:33:03,371 --> 00:33:12,057
And it cross-links all these proteins that are in the brain also that kind of these
neurofibrillary tangles and things like that, that actually increase inflammation in the
424
00:33:12,057 --> 00:33:12,407
brain.
425
00:33:12,407 --> 00:33:22,094
And pretty much all neurodegenerative diseases have a common denominator of
neuroinflammation or brain inflammation, right?
426
00:33:22,094 --> 00:33:27,237
So hydrogen is great for decreasing the oxidative stress associated with
neuroinflammation.
427
00:33:27,418 --> 00:33:32,491
Using something like TB006 to bind up, collect in three and decrease
428
00:33:32,491 --> 00:33:35,903
the inflammatory response improves cognitive ability.
429
00:33:35,903 --> 00:33:42,967
So even somebody that has pretty profound dementia can improve 63%, which has never been
shown before.
430
00:33:42,967 --> 00:33:48,030
And people with milder forms of cognitive impairment can improve 240%.
431
00:33:48,030 --> 00:33:55,641
So it's like you start to put these things together, know, hormone optimization and
thyroid and all the things we know how to do here.
432
00:33:55,641 --> 00:34:00,976
I mean, we're at a point where, you know, I've thought for a long time that heart disease
is optional.
433
00:34:01,909 --> 00:34:04,430
And now we're thinking that dementia is optional.
434
00:34:04,631 --> 00:34:14,556
And the other thing that we're doing on the cardiovascular front is we have access because
cardiovascular disease does affect brains as well, both via strokes and, and multi-infarct
435
00:34:14,556 --> 00:34:21,079
dementia where there's little, little emboli that go into the brain and cause micro
infarcts, if you will, or micro strokes.
436
00:34:21,220 --> 00:34:28,424
We have access to something called Capodex, which is cyclodextrin that mines up
cholesterol and pulls it out of plaque.
437
00:34:28,424 --> 00:34:30,775
So, you can actually pull.
438
00:34:30,775 --> 00:34:35,929
cholesterol out of plaque for the first time, not just try to decrease cholesterol, but
actually pull it out.
439
00:34:36,550 --> 00:34:37,891
that's the exciting part.
440
00:34:37,891 --> 00:34:45,097
The less exciting part is the fact that you, you, use it as an enema, daily for, but it's
only about five or six CCs.
441
00:34:45,858 --> 00:34:48,461
but, we're super excited about that too, right?
442
00:34:48,461 --> 00:34:51,944
mean, if you have, if you had significant blockage, it'd be like, yeah, I'll do that.
443
00:34:51,944 --> 00:34:52,254
Right.
444
00:34:52,254 --> 00:34:53,585
I want to get rid of that.
445
00:34:53,585 --> 00:34:56,505
So we're, running trials on all these things.
446
00:34:56,505 --> 00:34:56,978
we're involved.
447
00:34:56,978 --> 00:34:58,239
These are all under.
448
00:34:58,379 --> 00:35:01,255
IRB approved trials to sort of collect data and see what happens.
449
00:35:01,255 --> 00:35:07,109
But we're very excited about the whole field around both brain and heart health.
450
00:35:07,109 --> 00:35:07,879
Yeah.
451
00:35:08,013 --> 00:35:11,413
Well, listeners, if you are interested in heart health, Dr.
452
00:35:11,413 --> 00:35:15,473
Gladden has a tincture called the blood vessel formula.
453
00:35:15,473 --> 00:35:21,253
Use podcast 10 to get 10 % off your order in the checkout.
454
00:35:22,013 --> 00:35:35,993
And listeners, if you are interested in fighting dementia, if you're interested in
understanding more heart health, if you're interested in getting better care of your heart
455
00:35:35,993 --> 00:35:37,113
with Dr.
456
00:35:37,113 --> 00:35:37,687
Gladden,
457
00:35:37,687 --> 00:35:43,445
Go to gladdenlonggevity.com, fill out the form, reach out, someone will call you.
458
00:35:43,445 --> 00:35:43,895
And Dr.
459
00:35:43,895 --> 00:35:46,689
Gladden, there are ways in which to help get this paid.
460
00:35:46,689 --> 00:35:50,013
You guys have creative ways to make sure that.
461
00:35:50,097 --> 00:35:50,587
yeah.
462
00:35:50,587 --> 00:35:50,817
Yeah.
463
00:35:50,817 --> 00:35:53,829
People, people invest in themselves, free tax and things like that.
464
00:35:53,829 --> 00:35:55,860
So there's lots of ways to do that.
465
00:35:56,120 --> 00:36:05,295
And, yeah, the blood vessel formula is really, way for you to get the benefits of all the
med training herbs without having to eat a bushel of basil and arugula every day.
466
00:36:05,295 --> 00:36:05,576
Right.
467
00:36:05,576 --> 00:36:09,338
So kind of regular per se, but, summer savory and things like that.
468
00:36:09,338 --> 00:36:11,528
Sometimes that are hard to get ahold of.
469
00:36:12,049 --> 00:36:19,773
and then we have a mushroom formula also that's, five different mushrooms as the tincture
that, all turn off inflammation.
470
00:36:19,893 --> 00:36:26,293
So we use this in general for inflammatory control, if you will, but those two together
work really well.
471
00:36:26,293 --> 00:36:27,108
yeah.
472
00:36:27,595 --> 00:36:30,707
Listeners also, if you have a question for Dr.
473
00:36:30,707 --> 00:36:32,388
Gladden, submit it.
474
00:36:32,388 --> 00:36:34,839
Podcast at gladdenlongevity.com.
475
00:36:34,839 --> 00:36:39,231
That's podcast at gladdenlongevity.com.
476
00:36:39,231 --> 00:36:39,541
Dr.
477
00:36:39,541 --> 00:36:40,552
Gladden.
478
00:36:40,632 --> 00:36:41,058
Yes, sir.
479
00:36:41,058 --> 00:36:42,701
I see you next month, my man.
480
00:36:42,701 --> 00:36:44,384
All right, great to see you, Steve.
481
00:36:46,029 --> 00:36:47,077
you
482
00:36:48,525 --> 00:36:51,888
Thank you for listening to this week's episode of the Gladden Longevity Podcast.
483
00:36:51,888 --> 00:36:59,835
If you would like more information on what we've discussed or other topics, please
reference the show notes or go to gladdenlongevitypodcast.com.
484
00:36:59,835 --> 00:37:04,218
You can also find us on Instagram, Facebook, and Twitter by searching Gladden Longevity.
485
00:37:04,218 --> 00:37:12,905
If you've enjoyed this podcast, please subscribe to get future episodes delivered to you
and share our podcast or this episode with someone in your life that may find benefit.
486
00:37:12,946 --> 00:37:13,927
Thank you for listening.
487
00:37:13,927 --> 00:37:17,149
We'll be back next week with another exciting episode.
488
00:37:19,469 --> 00:37:22,782
The Glide and Longevity podcast is provided for informational purposes only.
489
00:37:22,782 --> 00:37:24,894
It does not constitute medical advice.
490
00:37:24,894 --> 00:37:30,059
This content is not intended to be a substitute for professional medical advice,
diagnosis, or treatment.
491
00:37:30,059 --> 00:37:36,465
Always seek the advice of a physician or other qualified health provider with any
questions you may have regarding a medical condition.
492
00:37:36,465 --> 00:37:41,509
The use of any information and materials linked to this podcast is at the listener's own
risk.
00:00:02,594 --> 00:00:04,996
Welcome to the Gliden Longevity Podcast with Dr.
2
00:00:04,996 --> 00:00:09,200
Jeffrey Gladden, where our passion is helping you become an AJAX.
3
00:00:09,200 --> 00:00:17,767
On this show, we want to help you optimize your life energy, longevity, health, and human
performance with impactful and actionable information.
4
00:00:17,968 --> 00:00:20,950
By answering four questions, how good can we be?
5
00:00:20,952 --> 00:00:22,883
How do we make 100 the new 30?
6
00:00:22,883 --> 00:00:24,833
How do we live well beyond 120?
7
00:00:24,833 --> 00:00:27,566
And how do we live young for a lifetime?
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00:00:27,566 --> 00:00:28,737
I'm Steve Ryder and Dr.
9
00:00:28,737 --> 00:00:29,667
Gladden.
10
00:00:29,667 --> 00:00:31,118
is February.
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00:00:31,118 --> 00:00:32,009
Yeah.
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00:00:32,009 --> 00:00:33,629
American heart month.
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00:00:34,050 --> 00:00:38,413
Valentine's was just last weekend from the time that we're recording this.
14
00:00:38,413 --> 00:00:40,904
Any special plans with MOOC?
15
00:00:41,223 --> 00:00:42,884
yeah, we had a lovely time.
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00:00:43,445 --> 00:00:52,302
Yeah, we, I've surprised her with a booking a hotel for Saturday night and a little
boutique hotel here in town.
17
00:00:52,302 --> 00:00:53,293
And, yeah.
18
00:00:53,293 --> 00:01:05,663
So we had, we had what we call a festival of joy where we just kind of hang out together
and yeah, just have a lot of really cool conversations, a lot of, sweet time together and
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00:01:05,663 --> 00:01:06,834
that was good.
20
00:01:06,834 --> 00:01:08,345
yeah, super fun.
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How about you?
22
00:01:09,906 --> 00:01:11,548
I would just relaxed.
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made, I made some soup rather than go out.
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made some soup.
25
00:01:15,793 --> 00:01:17,716
is my girlfriend's favorite soups.
26
00:01:17,716 --> 00:01:19,848
Both of them one Friday night and one Saturday night.
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And that was our, Valentine's weekend.
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kind of relax and chill and hanging out with the boys and.
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Cool.
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Awesome.
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I love it.
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Yeah, no, all good.
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Yeah.
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00:01:31,494 --> 00:01:33,675
So it's a birthday month for me too.
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I've got a birthday coming up a week from Friday.
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So that's cool.
37
00:01:38,447 --> 00:01:45,270
And my son and grandson are coming in town for the first grandfather, father, son weekend
together.
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He's six years old.
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00:01:46,141 --> 00:01:52,094
So I'm really looking forward to kind of breaking the ice on the on the guys weekends kind
of scenario.
40
00:01:52,094 --> 00:01:53,514
So that'll be super fun.
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00:01:54,002 --> 00:01:55,543
Nice.
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00:01:55,543 --> 00:01:56,563
Nice.
43
00:01:56,784 --> 00:02:04,948
So American heart month and we have some articles and a paper.
44
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Let's start out with sweet taste receptors in the heart.
45
00:02:09,190 --> 00:02:13,593
A new pathway for cardiac regulation.
46
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Yeah.
47
00:02:14,798 --> 00:02:21,748
From what I, from what I gathered on this, it's, know, if you're drinking artificial
sweeteners, it can cause your heart to be a little irregular.
48
00:02:21,748 --> 00:02:23,028
Is that right?
49
00:02:24,010 --> 00:02:25,151
Well, not exactly.
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00:02:25,151 --> 00:02:36,267
think what's interesting is we think that all heart rate response and strength of
contraction is controlled by, you know, either the nervous system, right?
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Putting more epinephrine down the sympathetic nervous system pathway to increase heart
rate and increase force of contraction or through hormones that are released from the
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adrenal glands, more adrenaline, you know, things epinephrine that do a similar kind of
thing, dopamine.
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00:02:53,056 --> 00:03:05,149
What this is pointing out though, is that they found that when they gave an artificial
sweetener, spartamine, and I'm sure that it's probably true for sugar as well, that the
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heart actually responds directly to that molecule and increases heart rate and force of
contraction, which is interesting.
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00:03:11,661 --> 00:03:21,244
So it's kind of like, you know, we've had this conversation before about, think that
eating is restorative, but it's actually has a stress component to it, right?
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Which is one of the reasons that
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00:03:23,286 --> 00:03:30,009
Eating one meal a day has been associated with increased mortality, 80 % increased
mortality over eating three meals a day.
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And we know fasting is good, but we know that we've come to understand that eating is
actually stressful.
59
00:03:34,351 --> 00:03:48,067
So if you're eating sugar or sweets or even artificial sweeteners, it looks like you're
stimulating your heart to have an increased force of contraction and an increased heart
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rate.
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Right.
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So that can be a good thing.
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If you have underlying heart disease, right, like you've had bypass or a stent or you
haven't had those, but you've got a significant blockage or something like that.
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It's interesting to know that eating the sugar not only is destroying the glycocalyx in
your arteries, right?
65
00:04:06,899 --> 00:04:15,806
That keeps your arteries healthy and allows them to dilate appropriately and not develop
plaque and lower blood pressure, et cetera, improve sexual function, athletic performance,
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brain function.
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But it's also directly now.
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stimulating the heart and that's kind of new information that sugar would actually
directly stimulate the heart in terms of force of contraction and heart rate.
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00:04:28,278 --> 00:04:29,860
So that's kind of cool.
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00:04:29,954 --> 00:04:33,356
What would be your general recommendations about this?
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Well, you have an option, I would go for a run because your heart's ready to go.
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00:04:40,882 --> 00:04:46,882
You know, I think if you're if your heart's healthy, it's just and you're and you're an
athlete.
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00:04:47,082 --> 00:04:58,622
There was an interesting study that was done where if you took carbohydrate, let's just
say sugar and you didn't swallow it, you simply put it in your mouth and swished it around
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for, I don't know, 15 seconds or so and spit it out.
75
00:05:03,628 --> 00:05:05,899
And then rinse your mouth out with water.
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00:05:06,539 --> 00:05:14,142
You actually had improved athletic performance just because the body perceived that it had
taken in carbohydrate.
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Yeah, that's crazy.
78
00:05:17,098 --> 00:05:18,144
Isn't that wild?
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So you didn't actually give your body more fuel.
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just sort of tricked it to thinking it got more fuel.
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And because of that, everything got better.
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00:05:27,588 --> 00:05:32,024
So it just goes to show you in that case that the nervous system really is kind of.
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00:05:32,024 --> 00:05:33,766
keeping the lid on everything, right?
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00:05:33,766 --> 00:05:43,194
It won't let you, if it thinks you're overstressing your muscles, too much exercise, too
much oxidative stress, it'll shut things down.
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00:05:43,194 --> 00:05:47,488
If it feels like you're depleting your nutrient resources, it shuts things down.
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00:05:47,488 --> 00:05:51,262
If it thinks the force on the muscle in the bone is too great, right?
87
00:05:51,262 --> 00:05:54,144
It might break the bone or whatever, it shuts things down, right?
88
00:05:54,144 --> 00:05:58,348
So it won't really allow you to lift a weight that's.
89
00:05:58,434 --> 00:06:01,705
You know, heavy enough to kind of break a bone unless you've got really fragile bones.
90
00:06:01,705 --> 00:06:10,990
But anyway, the point is, you've got sort of the central nervous system control, over what
it allows your body to do.
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00:06:10,990 --> 00:06:16,592
And when you proceed, when your central nervous system perceives that you've just gotten
carbohydrate says, okay.
92
00:06:16,592 --> 00:06:17,143
We're good to go.
93
00:06:17,143 --> 00:06:22,725
So it loosens things up and enables you to kind of, you know, run another three miles or
whatever.
94
00:06:22,725 --> 00:06:23,015
Right.
95
00:06:23,015 --> 00:06:25,076
So that's kind of, kind of interesting.
96
00:06:25,674 --> 00:06:41,184
So I remember when I got, when I tried out levels, the continuous glucose monitor, a post
meal walk or hike really helped to blunt that glucose response.
97
00:06:41,305 --> 00:06:54,534
And so I would assume you factor in the benefit of blood, of bringing that response down,
but the benefit of, you know, the, the increased cardio output, would that be
98
00:06:54,796 --> 00:06:54,997
Yeah.
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00:06:54,997 --> 00:06:57,217
Something that you would recommend even more.
100
00:06:57,630 --> 00:06:59,771
There's a couple of things going on there.
101
00:06:59,771 --> 00:07:08,173
We know that after a meal, particularly after dinner, society has us still sort of
believing that dinner should be a big meal, right?
102
00:07:08,173 --> 00:07:11,134
Where we know from a health perspective, it probably shouldn't be a big meal.
103
00:07:11,134 --> 00:07:12,414
It should be something.
104
00:07:12,414 --> 00:07:13,224
Could be something.
105
00:07:13,224 --> 00:07:18,416
But the bigger meal should be lunch or even a mix between breakfast and lunch.
106
00:07:19,216 --> 00:07:25,498
But if you go out for that walk afterwards, number one, when you're exercising, you tend
to slow
107
00:07:25,894 --> 00:07:28,245
Food digestion and absorption, right?
108
00:07:28,245 --> 00:07:29,085
So that's one thing.
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00:07:29,085 --> 00:07:41,568
The second thing is you're also sort of burning off some calories at the same time So you
kind of get kind of get a benefit for both and to your point since your body now Feels
110
00:07:41,568 --> 00:07:52,621
like it's replete with calories You know, it's kind of ready to go and your heart's kind
of ready to go anyway, so it's you just have to understand that if you have heart disease
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00:07:53,021 --> 00:07:55,246
You're pushing blood into your gut
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00:07:55,246 --> 00:07:59,746
to digest the food, which is one form of exercise for the heart.
113
00:07:59,746 --> 00:08:05,166
And then you're pushing blood to your muscles to be able to get you to exercise, which is
another form.
114
00:08:05,166 --> 00:08:07,066
So you're kind of doubling up on the exercise.
115
00:08:07,066 --> 00:08:16,506
So even though you're just going for a walk, you're kind of getting a more potent form of
exercise that way, which if you have heart disease could be too much, but if you're
116
00:08:16,506 --> 00:08:20,386
healthy, could be a really great way to go about it.
117
00:08:20,386 --> 00:08:25,066
So yeah, we like going for a walk after eating in the evening.
118
00:08:25,390 --> 00:08:30,744
So we have two articles about Takotsubo.
119
00:08:30,744 --> 00:08:31,687
Is how pronounce it?
120
00:08:31,687 --> 00:08:33,090
Yeah, it's Hakusubo.
121
00:08:33,090 --> 00:08:35,274
Takasubo syndrome.
122
00:08:36,137 --> 00:08:37,438
Broken heart.
123
00:08:38,783 --> 00:08:42,309
Talk about that because it looks like it's on the rise.
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00:08:42,860 --> 00:08:43,790
Yeah.
125
00:08:44,692 --> 00:08:58,443
well, it's probably on the rise, for a couple of different reasons, but also, since it was
first described back in the nineties in Japan, it's now become more universally
126
00:08:58,443 --> 00:08:59,264
recognized.
127
00:08:59,264 --> 00:09:02,036
And I think a lot of it was not recognized previously.
128
00:09:02,036 --> 00:09:02,296
Right.
129
00:09:02,296 --> 00:09:07,401
So it's hard to know if it's an incidence in occurrence or an incidence in observation of
it.
130
00:09:07,401 --> 00:09:07,931
Right.
131
00:09:07,931 --> 00:09:08,782
Yeah.
132
00:09:08,782 --> 00:09:09,683
appreciation of it.
133
00:09:09,683 --> 00:09:10,513
So,
134
00:09:12,226 --> 00:09:14,066
But yeah, Takasubo is interesting.
135
00:09:14,066 --> 00:09:25,213
I saw a number of cases when I was, you know, doing interventional cardiology work and
basically boils down to what's referred to as broken heart syndrome, where the heart is
136
00:09:25,213 --> 00:09:28,555
exposed to stress and it could be psychological stress.
137
00:09:28,555 --> 00:09:31,586
Could be physical stress, could be a combination of the two.
138
00:09:31,586 --> 00:09:40,901
It seems to affect women about 90 % of the time, 10 % of the time in men, can occur in men
and it's sense to happen in women that are post-menopausal.
139
00:09:42,112 --> 00:09:51,335
And so my hypothesis is that the female heart is not structurally quite as strong as a
man's heart.
140
00:09:51,335 --> 00:09:55,656
Just, you know, just like their bicep isn't structurally quite as strong as a man's bicep.
141
00:09:55,656 --> 00:09:59,707
The sex is just kind of a hormonal effect, if you will.
142
00:09:59,747 --> 00:10:07,209
And then when women are post-menopausal and depleted of hormones, they lose muscle mass.
143
00:10:07,209 --> 00:10:10,490
Men do the same thing, but they have a little more to start with.
144
00:10:11,200 --> 00:10:16,174
And the heart becomes a little more vulnerable to the effects of high stress.
145
00:10:16,174 --> 00:10:27,131
So the high stress, you know, it's it's it's typically characterized as a psychological
stress, like, you know, the loss of a loved one or, you know, a tsunami hits a village or,
146
00:10:27,131 --> 00:10:30,103
you know, something that's, you know, heartbreaking, if you will.
147
00:10:30,464 --> 00:10:40,046
And all of the release of catecholamines into the system, the epinephrine, the dopamine,
norepinephrine, all that dumps in and it overwhelms the heart in terms of
148
00:10:40,046 --> 00:10:41,706
what it's asking the heart to do, right?
149
00:10:41,706 --> 00:10:50,226
Speeding it up, forcing it to contract more vigorously, things like that in response to
all those stress hormones and the nervous system as well.
150
00:10:50,506 --> 00:10:53,906
And the heart just kind of shuts down, right?
151
00:10:53,906 --> 00:11:03,146
And so what happens is it kind of balloons out and instead of going from pumping out about
60 % of the blood with each beat that it's been filled up with, it doesn't pump out every
152
00:11:03,146 --> 00:11:07,306
last drop, but pumps out about 55, 60, 65 % of the blood.
153
00:11:07,406 --> 00:11:10,182
It may drop down to pumping out 15%.
154
00:11:10,629 --> 00:11:11,255
Right.
155
00:11:11,255 --> 00:11:12,157
Yeah.
156
00:11:12,229 --> 00:11:13,496
What does that cause?
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heart failure causes heart failure where you're not pumping enough blood and the blood
backs up into your lungs and people get pulmonary edema and they can die from that.
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it's like acute heart failure.
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It's also associated, depending times, with chest pain.
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So there's kind of a pain response to it as well, kind of like a heart attack.
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it many times is diagnosed, somebody comes in with acute heart attack symptoms, but they
don't show
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some of the classic findings of heart attack on the EKG.
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It's different kind of EKG and I'm not going to the EKG details because we don't have
pictures to show people, but it can be determined that it's not an acute heart attack.
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And when you take them to the cath lab, you see that the arteries are typically clear.
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There's no clot, there's no plaque, but the heart muscle itself is very weak and it
balloons out.
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If you can imagine the body of an octopus, how it's kind of that big body now it has all
the eight
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legs coming off, tentacles coming off.
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The heart kind of looks like that.
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It just looks like it's ballooned out and hardly contracts.
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So that's how it got to name Takasubo.
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It can also happen with physical stress and it can also happen with, let's say you're an
inpatient and you just had your gallbladder out or you just had a major surgery and you're
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under a lot of physical stress as well as emotional stress.
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can occur in that setting as well.
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So yeah, Takasubo, it's an interesting thing.
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really only accounts for probably two, three, four, five percent of people that are seen
in an emergency room, probably more around two percent.
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Again, women more than men.
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yeah.
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Interesting.
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What's the treatment?
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the treatment, it tends to get better.
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Reduced.
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Yeah.
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In our world, reducing stress.
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When a heart is strong enough doing low dose beta blockade to block the beta receptors
that this is where the epinephrine, norepinephrine things are reacting, alpha and beta
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blockers like Corag, Corvetilol, kind of rest the heart, kind of remove that.
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stimulus from the heart, it allows it to regain strength.
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And then you can do regenerative things here too, right?
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This is a place where some of the regenerative factors, whether it's stem cells or
placental derived trophic factors and cord blood factors and things like that can all be
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beneficial.
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And then improving hormone levels can be helpful.
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You know, where you do get testosterone and estrogen back.
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which makes all the tissues more sturdy, you will, enables them to manage that stress.
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So there's two things here.
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One to try to prevent it.
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One, I would do hormone replacement therapy so that you're, you know, you don't lose the
muscle mass, both not only in your arms and your legs, but in your heart.
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the second is monitoring how your body manages stress.
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And we're really big, have become big fans of brain tap, which is a device that's a visor
and headphones that
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you know, uses binaural beats and photobiomodulation through the eyes and the ears to
actually entrain your brain into a particular waveform like alpha for meditation or theta
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for deep meditation or delta for sleep.
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And you can actually train your nervous system to receive a stressful quote unquote
stressful input and yet have more equanimity around it, not be as impacted by it.
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There's also some interesting cognitive insights about that too.
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in terms of how to manage stress.
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So one of them is, many times the reason we feel stress is because we are identified or
associated or attached to a particular outcome.
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Right.
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And if we, if we don't, if we unattach ourselves from the outcome, right.
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This is kind of a perspective shift.
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Yes.
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You see, then all of a sudden, stress can be decreased dramatically, particularly when our
identity is caught up in it.
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Like, I, know, I'm here to do this job and you know, I didn't get something done on time
or whatever.
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now it's like, there's a threat to me, my own identity.
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I'm attached to that outcome.
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Right.
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Yeah.
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And so.
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A lot of stress comes from that and the inside of realizing that, I will actually be a
free individual if I, it's, it's not a question of not caring.
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It's not a question of not connecting.
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It's not even a question of not loving or participating or really trying hard.
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It's just not identifying with the outcome and attaching our identity and our self-worth
and everything else to that outcome.
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Right.
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That's really important to learn to separate that.
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Right.
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And then that will really help.
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manage stress dramatically,
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It's massive.
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It's massive.
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Once I started to do that, I noticed my overall stress levels significantly decrease.
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Hey, whatever happens, happens.
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Yeah.
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And it's not even, yeah, I mean, it can be that, and it doesn't mean you don't even care
about the outcome.
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Like you want a good thing to happen, but if it doesn't happen, it's like, but it's not,
it's not me.
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It's like, well, what can I do to be helpful here?
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Right.
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And so you get away from that being caught up with your identity tied to it.
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I once heard this speaker in the Christian communities give this thought, and it's never
ask the why question because it'll never be answered.
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Instead, ask, what does this mean and what must I do?
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And changing that kind of perspective can be massive.
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Yeah.
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Yeah, that's right.
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What I find is that when you are not attached to an outcome, right, like in this podcast,
for example, I'm not attached to an outcome as much as I love this podcast and I love
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having these conversations and I care about the audience, right.
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But I'm not attached to the outcome.
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My identity is not attached to the outcome.
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Yeah.
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And what that does is it frees me up psychically to do the podcast and not be fatigued or
tired at the end of it.
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Right.
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Or it also frees me up to be more, either both thoughtful or creative in my responses, my
thoughts.
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So it actually it's, you know, we talk about freedom all the time, right?
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We talk about freedom and yet everybody signs up for indentured servitude, right?
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They tie themselves to a job and a salary and a, and, and for me to be a good person, I've
got to do this and perform at that.
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You see what I'm saying?
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We all sign ourselves up for indentured servitude.
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And yet we can free ourselves from all that.
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And this is how you do it, is by unattaching.
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And that decreases stress and that will protect you from Takasubo.
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So that's my take on Takasubo.
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Dr.
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Gladden dropping truth bombs.
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Next article we've got, if you can do this many pushups, your heart is healthier than you
think.
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Dr.
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Gladden, truth or myth?
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What do you do to improve your heart health?
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Well, there are many, many, many, many metrics like this, right?
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You could say the longer you can hold a plank, the longer you can hang from a bar, the
more pull-ups you can do, the higher your VO2 max, really the stronger your hand grip
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strength is, right?
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So all of these things are really similar measures, if you will, of just total overall
body fitness.
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And I think
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What we're saying here is something obvious.
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If you're fit, you do better, right?
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You have more physiologic reserve.
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So you have the ability to be more anti-fragile, which is a really important concept,
right?
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So fragility, of course, is when something unexpected happens, we're damaged by it.
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Strength is, resilience is the ability to actually absorb that and recover from it.
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And then basically being
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really sturdy, so to speak, or strong means that you're not even impacted in the first
place, right?
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anyway, I think when we think about the body and being in shape, you just want to be in
the best shape that you can.
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And I will tell you that some insights I've had are that you never can get in shape in a
gym.
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And you can never get in shape without a What I mean by that is that when you train,
you're not training your muscles.
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Everybody goes to the gym because they're going to train today.
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It's upper body today.
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It's legs today.
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It's this actually being fit.
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or whatever.
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Being fit is actually having a nervous system that is fast and responsive and agile and
quick and balanced and all those kinds of things and powerful and strong, right?
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And to generate all that force.
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And so you're really, if you focus on the fact that you're training your nervous system,
you'll realize that you can't sit on a machine or do a limited range of motion something
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and really train the nervous system to be fast, agile, strong, quick and balanced, right?
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It's not gonna happen.
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Even if you're doing
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you curls on one leg.
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You have to put yourself in an environment that's unpredictable.
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And the only way you get that is to get outside.
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You've got the wind, you've got the rain, you've got the boulder in front of you.
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You've got the tree that fell down in front of you, whatever it is, you've got to have
your skiing, your walking, your hiking, your running, whatever, biking, whatever it is,
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you got to have unpredictability to train your nervous system to be adaptable to these
things.
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And I think that's why you can never really get in shape in a gym.
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And I think you also need a gym because you do need to sit there and do some, some squats
and you do some leg presses and some other stuff to actually build up just pure strength,
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if you will, which is also a nervous system situation.
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But when you carry that strength into the unexpected environment of the outdoors, now you
have the fun of like, yeah, I'm strong.
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I can pedal up this hill.
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Right.
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But now I've got to dodge that and hop this and whatever else.
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So anyway, that's how I think about it.
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What's your normal ratio of strength training outside all of that and how has it evolved
over the last number of years?
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Yeah, well, it's a function of the weather to some extent, and it's a function of the
status of my body.
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So if I'm injured, it's a little harder for me to do certain things outside.
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So I'm a little bit more confined to a gym, but even in a gym, I'll try to make it
unpredictable and I'll get outside as soon as I can.
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If I have access to the outside,
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I will be outside probably five days a week and I'll be in a gym two days a week would be
about the right ratio.
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When the weather's bad or it's cold or this or, know, and it's, I can't get out and run
for either a scheduling reason or something, you know, in reality, it probably works out
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to where I get outside three days a week and I'm inside four days a week, but I'm still
outside as much as I can be.
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Yeah.
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GLP-1s are being used to treat heart disease.
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I can assume you have some thoughts about this.
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Yeah.
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Well, I JLP ones were basically, mimic, you know, the hormones that are secreted when we
eat that, you know, basically indicate that we're full.
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And so they decrease appetite.
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They, and so they've been used for controlling blood sugars in the sense of decreasing
appetite.
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Also, they do seem to improve insulin sensitivity and improve beta cell function and
things like that.
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And so.
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You know, they really were developed for diabetes.
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but then it was found that, people are actually losing weight on these drugs.
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So then it became weight loss.
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At the same time, people were realizing that when diabetics would take JLP once they had a
lower incidence of heart attacks, right.
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And strokes.
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00:23:49,372 --> 00:23:52,694
And so there was been a cardiovascular benefit, right?
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There's an impact on lipid levels and, and, the way the heart responds to certain
stresses.
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So.
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It's really important to know that you're kind of enhancing a normal function in the body.
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The problem is that it's like anything.
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If you push it too hard, you start to get the negative effects.
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And so we see people that are, have become reliant on GLP-1s and GL1s to basically, you
know, lose weight.
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And what we find many times, because we measure everybody's
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body composition is that they're losing muscle instead of fat and they can be losing bone
density.
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00:24:34,151 --> 00:24:36,553
Now there are papers published on this as well.
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So while it's useful, particularly for diabetics and for decreasing cardiovascular events
in diabetics and even in non-diabetics, and it's also good for preserving kidney function,
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they have to be used cautiously at the same time.
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And so
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We're fans of, of going about it a little bit differently.
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We'll use GLP once to kind of jumpstart a situation if somebody wants to lose weight, but
we actually think that a five day fast mimicking diet is really a great jumpstart.
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it resets the gut, bio resets or taste buds resets or appetite.
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and then from there you can use Mimeo.
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We've had a podcast on Mimeo, right?
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00:25:23,467 --> 00:25:24,768
Which basically.
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has PEA and OEA and spermidine in it, a little bit of niacin.
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And the PEA and OEA, the OEA in particular, decreases appetite.
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So if you take three or four of those, now you're getting the benefits of appetite
suppression without loss of bone density or muscle mass.
347
00:25:45,593 --> 00:25:54,738
And you're getting spermidine, which is increasing basically autophagy in your cells and
you're increasing reverse cholesterol transport.
348
00:25:55,072 --> 00:25:58,965
So that's like a magical formula for keeping your arteries healthy.
349
00:25:58,965 --> 00:26:01,566
So we're big fans of that.
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And then there are also probiotics out there now that have GLP, that increased GLP-1
activity.
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And acromansia is one that is good for improving blood sugar control.
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So my point is if you're on a GLP-1 and you're listening to this, there are ways to get
you off of it.
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not lose ground and actually gain ground in terms of muscle mass, bone density and where
you really want to be.
354
00:26:29,419 --> 00:26:32,981
I think it's super important for people not to focus on the number on a scale.
355
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It's really body composition you want.
356
00:26:34,702 --> 00:26:39,385
And if you're serious about your health, get a scale that has a body composition component
to it.
357
00:26:39,385 --> 00:26:43,268
I think withings has one of those, I in body makes a scale.
358
00:26:43,268 --> 00:26:44,559
I think there's different ones out there.
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00:26:44,559 --> 00:26:45,969
You can resource.
360
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but if you
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00:26:46,894 --> 00:26:47,846
How accurate are those?
362
00:26:47,846 --> 00:26:49,719
Obviously it's not as...
363
00:26:49,721 --> 00:26:50,974
How accurate are those?
364
00:26:50,974 --> 00:26:51,946
Obviously it's not as...
365
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really matter.
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00:26:52,806 --> 00:26:54,886
It doesn't really matter in a sense.
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00:26:55,066 --> 00:26:56,206
It matters.
368
00:26:56,206 --> 00:26:57,826
Well, my point is it matters.
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They're not as accurate as the DEXA scan, right?
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00:27:00,446 --> 00:27:06,666
But they're accurate enough that you can see changes in a positive direction.
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00:27:06,666 --> 00:27:09,206
if muscle mass is going up, muscle mass is going up.
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00:27:09,206 --> 00:27:12,586
If fat, percent body fat's going down, percent body fat's going down.
373
00:27:12,586 --> 00:27:16,226
It doesn't matter if it's 18 % or 22 % even.
374
00:27:16,226 --> 00:27:18,846
It's the fact that it's moving in the right direction.
375
00:27:19,286 --> 00:27:21,598
So yes, you want to try to get one that's been
376
00:27:21,598 --> 00:27:23,782
know, verified and accurate.
377
00:27:24,486 --> 00:27:27,113
But the point is it's really the change that you're looking for.
378
00:27:27,113 --> 00:27:27,784
So, yeah.
379
00:29:20,267 --> 00:29:30,028
Well, you mentioned artery health and our last article is dietary salt substitutes to
prevent heart attack, stroke and death.
380
00:29:30,028 --> 00:29:38,288
Basically it's talking about using potassium rich salt as a salt alternative.
381
00:29:38,288 --> 00:29:38,578
Dr.
382
00:29:38,578 --> 00:29:39,860
Gladden, what are your thoughts?
383
00:29:39,860 --> 00:29:41,281
I'd never heard of this.
384
00:29:41,281 --> 00:29:48,264
Yeah, well, it turns out that, yeah, there's some really interesting things around salt,
right?
385
00:29:48,264 --> 00:29:51,305
So we all grew up with, you know, Morton salt, iodide salt, right?
386
00:29:51,305 --> 00:29:59,029
And then we got away from that because everybody got infatuated with sea salt and Celtic
salt and things like that, which is great because it is many salts.
387
00:29:59,029 --> 00:30:00,269
It's not just sodium chloride.
388
00:30:00,269 --> 00:30:02,190
It's actually many different minerals.
389
00:30:02,250 --> 00:30:09,227
And having all those minerals is actually really good because a lot of the time in our
pasteurized world, we don't get all those minerals.
390
00:30:09,227 --> 00:30:11,999
So using those kinds of salts are helpful.
391
00:30:12,220 --> 00:30:19,245
What's also known though, is that potassium rich foods help lower blood pressure and raise
potassium.
392
00:30:19,346 --> 00:30:28,213
And likewise, if you put some potassium chloride into your sodium chloride, or even some
potassium chloride into your Celtic sea salt, to where you're getting some potassium, some
393
00:30:28,213 --> 00:30:37,480
extra potassium, that's been shown to actually relax tension in the arteries and lower
blood pressure, improve heart function and...
394
00:30:37,801 --> 00:30:39,202
improve arterial function.
395
00:30:39,202 --> 00:30:48,970
So you can get potassium from, you know, things like potatoes, or they're higher in
potassium than bananas, for example, sweet potatoes and white potatoes.
396
00:30:48,970 --> 00:30:55,316
And if you want to refrigerate a baked potato overnight and turn it into a resistant
starch, you don't get all the carbs from it.
397
00:30:55,316 --> 00:30:59,539
You get resistant starch that feeds your gut biome and you're still getting the potassium.
398
00:30:59,539 --> 00:31:02,322
So there are many ways to boost potassium.
399
00:31:02,322 --> 00:31:05,594
You don't have that necessarily get a salt substitute to boost potassium.
400
00:31:05,594 --> 00:31:06,835
You do it with food.
401
00:31:06,945 --> 00:31:12,227
But the idea of having more potassium is a smart idea for hard function.
402
00:31:12,227 --> 00:31:17,309
We know that too much sodium pushes us into higher blood pressure and things like that.
403
00:31:17,309 --> 00:31:29,073
So it's not that salt is bad, especially if you're getting all the minerals from like a
Celtic sea salt or something, but too much pure sodium chloride is not what you're after.
404
00:31:30,817 --> 00:31:31,098
Dr.
405
00:31:31,098 --> 00:31:34,486
Gladden, February, what's the latest?
406
00:31:34,486 --> 00:31:35,037
What's new?
407
00:31:35,037 --> 00:31:37,653
What are you excited for in the next month?
408
00:31:38,253 --> 00:31:46,133
Um, well, we're, we're basically, um, starting a new brain optimization program here.
409
00:31:46,233 --> 00:31:48,133
So we're super excited about that.
410
00:31:48,133 --> 00:31:54,933
We're, coupling many of the technologies that we have here, both diagnostically and
therapeutically.
411
00:31:55,053 --> 00:32:03,253
And we've always used a Dale Bredesen's protocol here in terms of, you know, fixing the 36
holes in the roof that are associated with dementia.
412
00:32:03,253 --> 00:32:04,153
Yeah.
413
00:32:04,153 --> 00:32:05,697
And so.
414
00:32:05,697 --> 00:32:14,304
We've been all over that, but now we have a number of things that actually are very
additive to that in terms of regenerative therapies, trans-cranial magnetic stimulation
415
00:32:14,304 --> 00:32:25,264
and peptides and no tropics and regenerative technologies like placental derived exosomes
and stem cells and things like that.
416
00:32:25,264 --> 00:32:26,405
So you put all that together.
417
00:32:26,405 --> 00:32:32,900
It's pretty magical plasma freezes to kind of clear out the trash and the inflammation.
418
00:32:33,000 --> 00:32:34,273
And then we have.
419
00:32:34,273 --> 00:32:39,054
genetic testing to actually understand who's at risk for what kind of dementia, things
like that.
420
00:32:39,234 --> 00:32:49,717
And now we're just getting a hold of a new product called TB006, which is a monoclonal
antibody that binds a molecule called galectin 3.
421
00:32:49,717 --> 00:32:56,459
And galectin 3 is a major player in enhancing inflammation in the brain.
422
00:32:57,140 --> 00:33:02,901
It basically turns on the microglia in the brain, which are the immune cells in the brain.
423
00:33:03,371 --> 00:33:12,057
And it cross-links all these proteins that are in the brain also that kind of these
neurofibrillary tangles and things like that, that actually increase inflammation in the
424
00:33:12,057 --> 00:33:12,407
brain.
425
00:33:12,407 --> 00:33:22,094
And pretty much all neurodegenerative diseases have a common denominator of
neuroinflammation or brain inflammation, right?
426
00:33:22,094 --> 00:33:27,237
So hydrogen is great for decreasing the oxidative stress associated with
neuroinflammation.
427
00:33:27,418 --> 00:33:32,491
Using something like TB006 to bind up, collect in three and decrease
428
00:33:32,491 --> 00:33:35,903
the inflammatory response improves cognitive ability.
429
00:33:35,903 --> 00:33:42,967
So even somebody that has pretty profound dementia can improve 63%, which has never been
shown before.
430
00:33:42,967 --> 00:33:48,030
And people with milder forms of cognitive impairment can improve 240%.
431
00:33:48,030 --> 00:33:55,641
So it's like you start to put these things together, know, hormone optimization and
thyroid and all the things we know how to do here.
432
00:33:55,641 --> 00:34:00,976
I mean, we're at a point where, you know, I've thought for a long time that heart disease
is optional.
433
00:34:01,909 --> 00:34:04,430
And now we're thinking that dementia is optional.
434
00:34:04,631 --> 00:34:14,556
And the other thing that we're doing on the cardiovascular front is we have access because
cardiovascular disease does affect brains as well, both via strokes and, and multi-infarct
435
00:34:14,556 --> 00:34:21,079
dementia where there's little, little emboli that go into the brain and cause micro
infarcts, if you will, or micro strokes.
436
00:34:21,220 --> 00:34:28,424
We have access to something called Capodex, which is cyclodextrin that mines up
cholesterol and pulls it out of plaque.
437
00:34:28,424 --> 00:34:30,775
So, you can actually pull.
438
00:34:30,775 --> 00:34:35,929
cholesterol out of plaque for the first time, not just try to decrease cholesterol, but
actually pull it out.
439
00:34:36,550 --> 00:34:37,891
that's the exciting part.
440
00:34:37,891 --> 00:34:45,097
The less exciting part is the fact that you, you, use it as an enema, daily for, but it's
only about five or six CCs.
441
00:34:45,858 --> 00:34:48,461
but, we're super excited about that too, right?
442
00:34:48,461 --> 00:34:51,944
mean, if you have, if you had significant blockage, it'd be like, yeah, I'll do that.
443
00:34:51,944 --> 00:34:52,254
Right.
444
00:34:52,254 --> 00:34:53,585
I want to get rid of that.
445
00:34:53,585 --> 00:34:56,505
So we're, running trials on all these things.
446
00:34:56,505 --> 00:34:56,978
we're involved.
447
00:34:56,978 --> 00:34:58,239
These are all under.
448
00:34:58,379 --> 00:35:01,255
IRB approved trials to sort of collect data and see what happens.
449
00:35:01,255 --> 00:35:07,109
But we're very excited about the whole field around both brain and heart health.
450
00:35:07,109 --> 00:35:07,879
Yeah.
451
00:35:08,013 --> 00:35:11,413
Well, listeners, if you are interested in heart health, Dr.
452
00:35:11,413 --> 00:35:15,473
Gladden has a tincture called the blood vessel formula.
453
00:35:15,473 --> 00:35:21,253
Use podcast 10 to get 10 % off your order in the checkout.
454
00:35:22,013 --> 00:35:35,993
And listeners, if you are interested in fighting dementia, if you're interested in
understanding more heart health, if you're interested in getting better care of your heart
455
00:35:35,993 --> 00:35:37,113
with Dr.
456
00:35:37,113 --> 00:35:37,687
Gladden,
457
00:35:37,687 --> 00:35:43,445
Go to gladdenlonggevity.com, fill out the form, reach out, someone will call you.
458
00:35:43,445 --> 00:35:43,895
And Dr.
459
00:35:43,895 --> 00:35:46,689
Gladden, there are ways in which to help get this paid.
460
00:35:46,689 --> 00:35:50,013
You guys have creative ways to make sure that.
461
00:35:50,097 --> 00:35:50,587
yeah.
462
00:35:50,587 --> 00:35:50,817
Yeah.
463
00:35:50,817 --> 00:35:53,829
People, people invest in themselves, free tax and things like that.
464
00:35:53,829 --> 00:35:55,860
So there's lots of ways to do that.
465
00:35:56,120 --> 00:36:05,295
And, yeah, the blood vessel formula is really, way for you to get the benefits of all the
med training herbs without having to eat a bushel of basil and arugula every day.
466
00:36:05,295 --> 00:36:05,576
Right.
467
00:36:05,576 --> 00:36:09,338
So kind of regular per se, but, summer savory and things like that.
468
00:36:09,338 --> 00:36:11,528
Sometimes that are hard to get ahold of.
469
00:36:12,049 --> 00:36:19,773
and then we have a mushroom formula also that's, five different mushrooms as the tincture
that, all turn off inflammation.
470
00:36:19,893 --> 00:36:26,293
So we use this in general for inflammatory control, if you will, but those two together
work really well.
471
00:36:26,293 --> 00:36:27,108
yeah.
472
00:36:27,595 --> 00:36:30,707
Listeners also, if you have a question for Dr.
473
00:36:30,707 --> 00:36:32,388
Gladden, submit it.
474
00:36:32,388 --> 00:36:34,839
Podcast at gladdenlongevity.com.
475
00:36:34,839 --> 00:36:39,231
That's podcast at gladdenlongevity.com.
476
00:36:39,231 --> 00:36:39,541
Dr.
477
00:36:39,541 --> 00:36:40,552
Gladden.
478
00:36:40,632 --> 00:36:41,058
Yes, sir.
479
00:36:41,058 --> 00:36:42,701
I see you next month, my man.
480
00:36:42,701 --> 00:36:44,384
All right, great to see you, Steve.
481
00:36:46,029 --> 00:36:47,077
you
482
00:36:48,525 --> 00:36:51,888
Thank you for listening to this week's episode of the Gladden Longevity Podcast.
483
00:36:51,888 --> 00:36:59,835
If you would like more information on what we've discussed or other topics, please
reference the show notes or go to gladdenlongevitypodcast.com.
484
00:36:59,835 --> 00:37:04,218
You can also find us on Instagram, Facebook, and Twitter by searching Gladden Longevity.
485
00:37:04,218 --> 00:37:12,905
If you've enjoyed this podcast, please subscribe to get future episodes delivered to you
and share our podcast or this episode with someone in your life that may find benefit.
486
00:37:12,946 --> 00:37:13,927
Thank you for listening.
487
00:37:13,927 --> 00:37:17,149
We'll be back next week with another exciting episode.
488
00:37:19,469 --> 00:37:22,782
The Glide and Longevity podcast is provided for informational purposes only.
489
00:37:22,782 --> 00:37:24,894
It does not constitute medical advice.
490
00:37:24,894 --> 00:37:30,059
This content is not intended to be a substitute for professional medical advice,
diagnosis, or treatment.
491
00:37:30,059 --> 00:37:36,465
Always seek the advice of a physician or other qualified health provider with any
questions you may have regarding a medical condition.
492
00:37:36,465 --> 00:37:41,509
The use of any information and materials linked to this podcast is at the listener's own
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